alendronate has been researched along with Aseptic Necrosis of Femur Head in 28 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a retrospective study in our facility for comparing the pharmacological effects of teriparatide and alendronate on 32 NOFH patients diagnosed with osteoporosis." | 3.85 | Efficacy of teriparatide in the treatment of nontraumatic osteonecrosis of the femoral head: a retrospective comparative study with alendronate. ( Arai, R; Asano, T; Inoue, M; Irie, T; Iwasaki, N; Kondo, E; Konno, T; Onodera, T; Takahashi, D; Terkawi, MA, 2017) |
| "Alendronate reduces pain, improves function and retards AVN progression." | 3.73 | Efficacy of alendronate, a bisphosphonate, in the treatment of AVN of the hip. A prospective open-label study. ( Agarwala, S; Jain, D; Joshi, VR; Sule, A, 2005) |
| "Alendronate has no obvious effect on preventing the necessity for THA, reducing disease progression, or improving life quality." | 2.77 | Alendronate in the prevention of collapse of the femoral head in nontraumatic osteonecrosis: a two-year multicenter, prospective, randomized, double-blind, placebo-controlled study. ( Chang, CH; Chang, JK; Chen, CH; Hou, SM; Lai, KA; Wang, GJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (42.86) | 29.6817 |
| 2010's | 14 (50.00) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, H | 1 |
| Lao, Y | 1 |
| Zhang, S | 1 |
| Ding, W | 1 |
| Lu, D | 1 |
| Xu, B | 1 |
| Rong, K | 1 |
| Li, X | 1 |
| Jiang, W | 1 |
| Wu, X | 1 |
| Xia, Q | 1 |
| Chen, J | 1 |
| Yin, X | 1 |
| Yu, X | 1 |
| Zhang, D | 1 |
| Chen, X | 1 |
| Yang, J | 2 |
| Shi, L | 1 |
| Pang, Q | 1 |
| Wang, W | 1 |
| Zhang, N | 1 |
| Guo, W | 1 |
| Gao, F | 1 |
| Peled, E | 3 |
| Bejar, J | 2 |
| Barak, M | 1 |
| Orion, E | 1 |
| Norman, D | 3 |
| Luo, RB | 1 |
| Lin, T | 1 |
| Zhong, HM | 1 |
| Yan, SG | 1 |
| Wang, JA | 1 |
| Wang, CJ | 3 |
| Cheng, JH | 1 |
| Huang, CC | 3 |
| Yip, HK | 1 |
| Russo, S | 1 |
| Roth, A | 2 |
| Beckmann, J | 2 |
| Smolenski, U | 2 |
| Fischer, A | 2 |
| Jäger, M | 2 |
| Tingart, M | 2 |
| Rader, C | 2 |
| Peters, KM | 2 |
| Reppenhagen, S | 2 |
| Nöth, U | 2 |
| Heiss, C | 1 |
| Maus, U | 2 |
| Bohndorf, K | 1 |
| Heiß, C | 1 |
| Kenn, W | 1 |
| Kopp, I | 1 |
| Sirotin, I | 1 |
| Breusch, SJ | 1 |
| Arai, R | 1 |
| Takahashi, D | 1 |
| Inoue, M | 1 |
| Irie, T | 1 |
| Asano, T | 1 |
| Konno, T | 1 |
| Terkawi, MA | 1 |
| Onodera, T | 1 |
| Kondo, E | 1 |
| Iwasaki, N | 1 |
| Zinman, C | 1 |
| Boss, JH | 1 |
| Reis, DN | 1 |
| Hofstaetter, JG | 1 |
| Wang, J | 1 |
| Yan, J | 1 |
| Glimcher, MJ | 1 |
| Hsu, SL | 1 |
| Lee, MS | 2 |
| Chan, YS | 2 |
| Yang, KD | 2 |
| Agarwala, S | 5 |
| Shah, S | 1 |
| Joshi, VR | 4 |
| Shah, SB | 1 |
| Kang, P | 1 |
| Pei, F | 1 |
| Shen, B | 1 |
| Zhou, Z | 1 |
| Cheon, SH | 1 |
| Oh, CW | 1 |
| Park, SK | 1 |
| Chen, CH | 1 |
| Chang, JK | 1 |
| Lai, KA | 2 |
| Hou, SM | 1 |
| Chang, CH | 1 |
| Wang, GJ | 1 |
| Davis, M | 1 |
| Axelman, E | 1 |
| Nadir, Y | 1 |
| Jain, D | 1 |
| Sule, A | 3 |
| Bowers, JR | 1 |
| Dailiana, ZH | 1 |
| McCarthy, EF | 1 |
| Urbaniak, JR | 1 |
| Desai, MM | 1 |
| Sonone, S | 1 |
| Bhasme, V | 1 |
| Shen, WJ | 1 |
| Yang, CY | 1 |
| Shao, CJ | 1 |
| Hsu, JT | 1 |
| Lin, RM | 1 |
| Nishii, T | 2 |
| Sugano, N | 2 |
| Miki, H | 2 |
| Hashimoto, J | 2 |
| Yoshikawa, H | 2 |
| Wang, FS | 1 |
| Wang, JW | 1 |
| Ko, JY | 1 |
| Pai, BU | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alendronate in the Prevention of Collapse of Femoral Head in Non-Traumatic Osteonecrosis[NCT00265252] | Phase 4 | 60 participants | Interventional | 2005-06-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for alendronate and Aseptic Necrosis of Femur Head
| Article | Year |
|---|---|
Effectiveness of various hip preservation treatments for non-traumatic osteonecrosis of the femoral head: A network meta-analysis of randomized controlled trials.
Topics: Alendronate; Conservative Treatment; Female; Femur Head Necrosis; High-Energy Shock Waves; Humans; M | 2018 |
Evidence for using alendronate to treat adult avascular necrosis of the femoral head: a systematic review.
Topics: Adolescent; Adult; Aged; Alendronate; Demography; Female; Femur Head Necrosis; Humans; Male; Middle | 2014 |
Extracorporeal shockwave therapy for avascular necrosis of femoral head.
Topics: Alendronate; Bone Density Conservation Agents; Combined Modality Therapy; Femur Head Necrosis; High- | 2015 |
S3-Guideline non-traumatic adult femoral head necrosis.
Topics: Adult; Alendronate; Arthroplasty, Replacement, Hip; Bone Density Conservation Agents; Decompression, | 2016 |
[Bisphosphonate treatment in osteonecrosis of the femoral head].
Topics: Alendronate; Animals; Bone Density Conservation Agents; Clinical Trials as Topic; Diphosphonates; Di | 2007 |
5 trials available for alendronate and Aseptic Necrosis of Femur Head
| Article | Year |
|---|---|
Cocktail therapy for femoral head necrosis of the hip.
Topics: Adolescent; Adult; Aged; Alendronate; Chi-Square Distribution; Combined Modality Therapy; Female; Fe | 2010 |
Are the results of multiple drilling and alendronate for osteonecrosis of the femoral head better than those of multiple drilling? A pilot study.
Topics: Adult; Alendronate; Bone Density Conservation Agents; Combined Modality Therapy; Decompression, Surg | 2012 |
Alendronate in the prevention of collapse of the femoral head in nontraumatic osteonecrosis: a two-year multicenter, prospective, randomized, double-blind, placebo-controlled study.
Topics: Adult; Alendronate; Arthroplasty, Replacement, Hip; Bone Density Conservation Agents; Double-Blind M | 2012 |
The use of alendronate to prevent early collapse of the femoral head in patients with nontraumatic osteonecrosis. A randomized clinical study.
Topics: Adult; Aged; Alendronate; Bone Diseases; Diphosphonates; Disease Progression; Female; Femur Head Nec | 2005 |
Treatment of osteonecrosis of the hip: comparison of extracorporeal shockwave with shockwave and alendronate.
Topics: Administration, Oral; Adolescent; Adult; Alendronate; Bone Density Conservation Agents; Combined Mod | 2008 |
18 other studies available for alendronate and Aseptic Necrosis of Femur Head
| Article | Year |
|---|---|
Combined Pharmacotherapy with Alendronate and Desferoxamine Regulate the Bone Resorption and Bone Regeneration for Preventing Glucocorticoids-Induced Osteonecrosis of the Femoral Head.
Topics: Alendronate; Animals; beta Catenin; Bone Regeneration; Bone Resorption; Deferoxamine; Drug Therapy, | 2020 |
Alendronate Alleviated Femoral Head Necrosis and Upregulated BMP2/EIF2AK3/EIF2A/ATF4 Pathway in Liquid Nitrogen Treated Rats.
Topics: Activating Transcription Factor 4; Alendronate; Animals; Bone Morphogenetic Protein 2; eIF-2 Kinase; | 2021 |
Combined pharmacotherapy for osteonecrosis of the femoral head after severe acute respiratory syndrome and interstitial pneumonia: two and a half to fourteen year follow-up.
Topics: Adult; Alendronate; Alprostadil; Bone Density Conservation Agents; Drug Therapy, Combination; Enoxap | 2018 |
Core decompression and alendronate treatment of the osteonecrotic rat femoral head: computer-assisted analysis.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Combined Modality Therapy; Decompression, Su | 2013 |
[S3 guideline. Part 2: Non-Traumatic Avascular Femoral Head Necrosis in Adults - Untreated Course and Conservative Treatment].
Topics: Alendronate; Bone Density Conservation Agents; Evidence-Based Medicine; Female; Femoral Fractures; F | 2015 |
Efficacy of teriparatide in the treatment of nontraumatic osteonecrosis of the femoral head: a retrospective comparative study with alendronate.
Topics: Adult; Alendronate; Bone Density Conservation Agents; Bone Resorption; Disease Progression; Drug Eva | 2017 |
Prevention of distortion of vascular deprivation-induced osteonecrosis of the rat femoral head by treatment with alendronate.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Female; Femur Head; Femur Head Necrosis; Rat | 2009 |
The effects of alendronate in the treatment of experimental osteonecrosis of the hip in adult rabbits.
Topics: Acetabulum; Adult; Alendronate; Animals; Bone Density; Bone Density Conservation Agents; Bone Remode | 2009 |
The use of alendronate in the treatment of avascular necrosis of the femoral head: follow-up to eight years.
Topics: Administration, Oral; Adult; Alendronate; Bone Density Conservation Agents; Female; Femoral Fracture | 2009 |
Ten-year follow-up of avascular necrosis of femoral head treated with alendronate for 3 years.
Topics: Adult; Alendronate; Bone Density Conservation Agents; Disease Progression; Female; Femur Head Necros | 2011 |
Osteonecrosis of femoral head treated with alendronate in a 14-year-old boy: a case report.
Topics: Adolescent; Alendronate; Bone Density Conservation Agents; Femur Head Necrosis; Humans; Male; Treatm | 2012 |
Heparanase role in the treatment of avascular necrosis of femur head.
Topics: Alendronate; Animals; Bone Density Conservation Agents; Combined Modality Therapy; Decompression, Su | 2013 |
Efficacy of alendronate, a bisphosphonate, in the treatment of AVN of the hip. A prospective open-label study.
Topics: Adolescent; Adult; Aged; Alendronate; Bone Resorption; Disability Evaluation; Female; Femur Head Nec | 2005 |
Drug therapy increases bone density in osteonecrosis of the femoral head in canines.
Topics: Alendronate; Animals; Bone Density; Dogs; Femur Head Necrosis; Hydroxymethylglutaryl-CoA Reductase I | 2004 |
Efficacy of alendronate in the treatment of avascular necrosis of the hip.
Topics: Alendronate; Disease Progression; Femur Head Necrosis; Humans; Magnetic Resonance Imaging; Treatment | 2005 |
Does alendronate prevent collapse in osteonecrosis of the femoral head?
Topics: Adolescent; Adult; Aged; Alendronate; Alkaline Phosphatase; Biomarkers; Bone Density Conservation Ag | 2006 |
Study of alendronate in avascular necrosis of bone.
Topics: Alendronate; Femur Head Necrosis; Follow-Up Studies; Humans; Lupus Erythematosus, Systemic; Male; Ra | 2001 |
Alendronate in the treatment of avascular necrosis of the hip.
Topics: Adult; Alendronate; Disability Evaluation; Female; Femur Head Necrosis; Gait; Hip Joint; Humans; Mal | 2002 |