Page last updated: 2024-10-22

alendronate and Arthropathy, Neurogenic

alendronate has been researched along with Arthropathy, Neurogenic in 4 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Arthropathy, Neurogenic: Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" They differed markedly in study type, pharmacological agent used, dosing regimen, disease, aetiology/stage/location, concurrent off-loading regimen, outcomes and, follow-up."2.49A Surgeon's guide to advances in the pharmacological management of acute Charcot neuroarthropathy. ( Afsie, S; Al-Nammari, SS; Timothy, T, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Nammari, SS1
Timothy, T1
Afsie, S1
Molines, L1
Darmon, P1
Raccah, D1
Pitocco, D2
Ruotolo, V2
Caputo, S2
Mancini, L2
Collina, CM1
Manto, A2
Caradonna, P2
Ghirlanda, G2
Collina, MC1
Musella, T1
Galli, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Treatment With DENOsumab of an Acute CHARCOT Foot in Patients With Diabetes. A Multicenter, Double-blind, Randomized, Placebo-controlled Trial.[NCT04547348]Phase 338 participants (Anticipated)Interventional2020-11-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for alendronate and Arthropathy, Neurogenic

ArticleYear
A Surgeon's guide to advances in the pharmacological management of acute Charcot neuroarthropathy.
    Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 2013, Volume: 19, Issue:4

    Topics: Alendronate; Alkaline Phosphatase; Arthropathy, Neurogenic; Bone Density Conservation Agents; Calcit

2013
Charcot's foot: newest findings on its pathophysiology, diagnosis and treatment.
    Diabetes & metabolism, 2010, Volume: 36, Issue:4

    Topics: Alendronate; Arthropathy, Neurogenic; Biomarkers; Bone Density Conservation Agents; Calcitonin; Diab

2010
Interaction between IGF-1, inflammation, and neuropathy in the pathogenesis of acute charcot neuroarthropathy: lessons from alendronate therapy and future perspectives of medical therapy.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2008, Volume: 40, Issue:3

    Topics: Acute Disease; Alendronate; Arthropathy, Neurogenic; Bone Density Conservation Agents; Bone Resorpti

2008

Trials

1 trial available for alendronate and Arthropathy, Neurogenic

ArticleYear
Six-month treatment with alendronate in acute Charcot neuroarthropathy: a randomized controlled trial.
    Diabetes care, 2005, Volume: 28, Issue:5

    Topics: Acute Disease; Alendronate; Arthropathy, Neurogenic; Bone Resorption; Diabetic Neuropathies; Disabil

2005