alendronate and Arthralgia studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

Excerpt	Relevance	Reference
"A total of 140 postmenopausal women or men aged older than 50 years who met the indications for osteoporosis treatment were randomized to receive either generic (Bonmax®) or brand alendronate (Fosamax®) 70 mg/week over a 12-month period during the May 2014 to June 2015 study period."	9.24	Randomized clinical trial comparing efficacy and safety of brand versus generic alendronate (Bonmax®) for osteoporosis treatment. ( Jarusriwanna, A; Songcharoen, P; Unnanuntana, A, 2017)
"A total of 140 postmenopausal women or men aged older than 50 years who met the indications for osteoporosis treatment were randomized to receive either generic (Bonmax®) or brand alendronate (Fosamax®) 70 mg/week over a 12-month period during the May 2014 to June 2015 study period."	5.24	Randomized clinical trial comparing efficacy and safety of brand versus generic alendronate (Bonmax®) for osteoporosis treatment. ( Jarusriwanna, A; Songcharoen, P; Unnanuntana, A, 2017)
"Patients with symptoms of osteoporosis, prostate cancer, or breast cancer were surveyed to determine their knowledge of bisphosphonates."	1.38	Awareness and education of patients receiving bisphosphonates. ( Bauer, JS; Beck, N; Eitner, S; Kiefer, J; Stockmann, P; Wichmann, M, 2012)

Research

Studies (8)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Bone Mineral Density (BMD) at Lumbar Spine (L1-L4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (37.50)	29.6817
2010's	4 (50.00)	24.3611
2020's	1 (12.50)	2.80

Authors	Studies
Sifrig, B	1
Grozenski, A	1
Brown, L	1
Coleman, J	1
Unnanuntana, A	1
Jarusriwanna, A	1
Songcharoen, P	1
Basile, P	1
Falk, N	1
Vaishya, R	1
Vijay, V	1
Vaish, A	1
Bauer, JS	1
Beck, N	1
Kiefer, J	1
Stockmann, P	1
Wichmann, M	1
Eitner, S	1
Gerster, JH	1
Wysowski, DK	1
Chang, JT	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Randomized Trial Comparing Efficacy and Safety of Brand Versus Generic Alendronate for Osteoporosis Treatment[NCT02371252]	Phase 4	140 participants (Actual)	Interventional	2014-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Percent changes of bone mineral density at lumbar spine (L1-L4) from baseline to 1-year after treatment will be compared and analysed between 2 groups. (NCT02371252)
Timeframe: 1 year after treatment

Bone Mineral Density (BMD) at Total Hip

Intervention	percent (Mean)
Original Alendronate (Fosamax)	5.54
Generic Alendronate (Bonmax)	5.39

Percent changes of bone mineral density at total hip from baseline to 1-year after treatment will be compared and analysed between 2 groups. (NCT02371252)
Timeframe: 1 year after treatment

Article	Year
An Uncommon Cause of Debilitating Hip Pain in Pregnancy. Current sports medicine reports, 2021, Feb-01, Volume: 20, Issue:2 Topics: Adult; Alendronate; Arthralgia; Bed Rest; Bone Density Conservation Agents; Crutches; Female; Hip; H	2021
Anterolateral hip pain · no specific injury · Dx? The Journal of family practice, 2018, Volume: 67, Issue:8 Topics: Alendronate; Arthralgia; Athletes; Bone Density Conservation Agents; Glucocorticoids; Hip Joint; Hoc	2018
Spontaneous osteonecrosis of the knee: an unusual cause of knee pain. BMJ case reports, 2014, Apr-30, Volume: 2014 Topics: Acute Disease; Adult; Alendronate; Arthralgia; Diclofenac; Disease Progression; Humans; Knee Joint;	2014
Awareness and education of patients receiving bisphosphonates. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2012, Volume: 40, Issue:3 Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Arthralgia; Bisphosphonate-Associated Os	2012
Acute polyarthritis related to once-weekly alendronate in a woman with osteoporosis. The Journal of rheumatology, 2004, Volume: 31, Issue:4 Topics: Acute Disease; Alendronate; Arthralgia; Arthritis; Drug Administration Schedule; Female; Humans; Joi	2004
Alendronate and risedronate: reports of severe bone, joint, and muscle pain. Archives of internal medicine, 2005, Feb-14, Volume: 165, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alendronate; Arthralgia; Bone and Bones; Child; Etidroni	2005
Alendronic acid: synovitis, myalgia and arthralgia. Prescrire international, 2007, Volume: 16, Issue:88 Topics: Alendronate; Arthralgia; Diphosphonates; Female; Humans; Musculoskeletal Diseases; New Zealand; Syno	2007

Intervention	percent (Mean)
Original Alendronate (Fosamax)	2.48
Generic Alendronate (Bonmax)	2.52

alendronate and Arthralgia