alendronate has been researched along with Angiogenesis, Pathologic in 5 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that a self-suspendable nanoparticulate dosage form, with a minimum amount of expients, could be formulated by complexing the negatively charged alendronate with gallium or gadolinium." | 5.34 | Nanosuspensions of alendronate with gallium or gadolinium attenuate neointimal hyperplasia in rats. ( Berger, V; Eisenberg, G; Epstein, H; Gao, J; Golomb, G; Koroukhov, N; Levi, I, 2007) |
| "Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood." | 1.35 | Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice. ( Härkönen, PL; Tuomela, JM; Väänänen, K; Valta, MP, 2008) |
| " We hypothesized that a self-suspendable nanoparticulate dosage form, with a minimum amount of expients, could be formulated by complexing the negatively charged alendronate with gallium or gadolinium." | 1.34 | Nanosuspensions of alendronate with gallium or gadolinium attenuate neointimal hyperplasia in rats. ( Berger, V; Eisenberg, G; Epstein, H; Gao, J; Golomb, G; Koroukhov, N; Levi, I, 2007) |
| "Alendronate treatment reduced the intra-tumor neoangiogenesis compared with that in the non-treated mice, although tumor-derived VEGF expression was not altered." | 1.34 | Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells. ( Hashimoto, K; Kimura, T; Morishige, K; Ogata, S; Sakata, M; Sawada, K; Shimizu, S; Tahara, M; Tasaka, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Zhao, Y | 1 |
| Zhang, D | 1 |
| Qi, B | 1 |
| Xiao, W | 1 |
| Hu, X | 1 |
| Yu, A | 1 |
| Epstein, H | 1 |
| Berger, V | 1 |
| Levi, I | 1 |
| Eisenberg, G | 1 |
| Koroukhov, N | 1 |
| Gao, J | 1 |
| Golomb, G | 1 |
| Hashimoto, K | 1 |
| Morishige, K | 2 |
| Sawada, K | 2 |
| Tahara, M | 1 |
| Shimizu, S | 1 |
| Ogata, S | 2 |
| Sakata, M | 2 |
| Tasaka, K | 1 |
| Kimura, T | 2 |
| Tuomela, JM | 1 |
| Valta, MP | 1 |
| Väänänen, K | 1 |
| Härkönen, PL | 1 |
| Mabuchi, S | 1 |
| Kawase, C | 1 |
5 other studies available for alendronate and Angiogenesis, Pathologic
| Article | Year |
|---|---|
A novel hybrid compound LLP2A-alendronate accelerates open fracture healing in a rabbit model.
Topics: Alendronate; Animals; Dipeptides; Disease Models, Animal; Female; Fracture Healing; Male; Neovascula | 2019 |
Nanosuspensions of alendronate with gallium or gadolinium attenuate neointimal hyperplasia in rats.
Topics: Alendronate; Angiogenesis Inhibitors; Animals; Cell Line; Cell Proliferation; Chemistry, Pharmaceuti | 2007 |
Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells.
Topics: Alendronate; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Cells, Cultured; End | 2007 |
Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice.
Topics: Adenocarcinoma; Alendronate; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Divi | 2008 |
In vitro and in vivo assays to analyze the contribution of Rho kinase in angiogenesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alendronate; Animals; Cell Culture Techniques; Cell M | 2008 |