Page last updated: 2024-10-22

alendronate and Adjuvant Arthritis

alendronate has been researched along with Adjuvant Arthritis in 9 studies

alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.

Research Excerpts

ExcerptRelevanceReference
"To employ elemental Strontium as a tracer of bone turnover, in the presence (or absence) of the bisphosphonate drug Alendronate, in order to spatially map osteophytogenesis and other bone turnover in rats developing post-traumatic secondary osteoarthritis (PTOA)."7.78Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium as a molecular tracer of bone formation. ( Doschak, MR; Maksymowych, WP; Panahifar, A, 2012)
"To employ elemental Strontium as a tracer of bone turnover, in the presence (or absence) of the bisphosphonate drug Alendronate, in order to spatially map osteophytogenesis and other bone turnover in rats developing post-traumatic secondary osteoarthritis (PTOA)."3.78Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium as a molecular tracer of bone formation. ( Doschak, MR; Maksymowych, WP; Panahifar, A, 2012)
"In the rats with adjuvant arthritis, BMD of either end of the tibia was lower than in normal rats."1.33Differences in osteoclast formation between proximal and distal tibial osteoporosis in rats with adjuvant arthritis: inhibitory effects of bisphosphonates on osteoclasts. ( Nagashima, M; Shu, G; Yamamoto, K, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xie, Z1
Liu, G1
Tang, P1
Sun, X1
Chen, S1
Qin, A1
Zhu, P1
Zhang, J1
Fan, S1
Mohan, G1
Perilli, E1
Parkinson, IH1
Humphries, JM1
Fazzalari, NL1
Kuliwaba, JS1
Panahifar, A1
Maksymowych, WP1
Doschak, MR1
Netsu, T1
Kondo, N1
Arai, K1
Ogose, A1
Endo, N1
Harada, H1
Nakayama, T1
Nanaka, T1
Katsumata, T1
Itoh, F1
Aoyagi, S1
Kusama, H1
Kojima, M1
Kogo, H1
Zhang, Q1
Badell, IR1
Schwarz, EM1
Boulukos, KE1
Yao, Z1
Boyce, BF1
Xing, L1
Kawabata, A1
Kawao, N1
Hironaka, Y1
Ishiki, T1
Matsunami, M1
Sekiguchi, F1
Shu, G1
Yamamoto, K1
Nagashima, M1

Other Studies

9 other studies available for alendronate and Adjuvant Arthritis

ArticleYear
Bone-targeted methotrexate-alendronate conjugate inhibits osteoclastogenesis in vitro and prevents bone loss and inflammation of collagen-induced arthritis in vivo.
    Drug delivery, 2018, Volume: 25, Issue:1

    Topics: Alendronate; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Bone and Bones; Bone Resorptio

2018
Pre-emptive, early, and delayed alendronate treatment in a rat model of knee osteoarthritis: effect on subchondral trabecular bone microarchitecture and cartilage degradation of the tibia, bone/cartilage turnover, and joint discomfort.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:10

    Topics: Alendronate; Animals; Arthritis, Experimental; Bone Density Conservation Agents; Cartilage Oligomeri

2013
Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium as a molecular tracer of bone formation.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:7

    Topics: Alendronate; Animals; Arthritis, Experimental; Bone Density Conservation Agents; Drug Evaluation, Pr

2012
Osteoconductive action of alendronate after implantation of beta tricalcium phosphate in rat adjuvant-induced arthritis.
    Journal of bone and mineral metabolism, 2012, Volume: 30, Issue:6

    Topics: Acid Phosphatase; Alendronate; Animals; Arthritis, Experimental; Calcification, Physiologic; Calcium

2012
Effects of bisphosphonates on joint damage and bone loss in rat adjuvant-induced arthritis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:2

    Topics: Alendronate; Animals; Arthritis, Experimental; Bone Density; Bone Resorption; Diphosphonates; Etidro

2004
Effects of clodronate and alendronate on local and systemic changes in bone metabolism in rats with adjuvant arthritis.
    Inflammation, 2004, Volume: 28, Issue:1

    Topics: Alendronate; Animals; Arthritis, Experimental; Bone and Bones; Clodronic Acid; Male; Osteogenesis; R

2004
Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:9

    Topics: Alendronate; Animals; Apoptosis; Arthritis, Experimental; bcl-X Protein; Bone Marrow Cells; Cell Sur

2005
Antiallodynic effect of etidronate, a bisphosphonate, in rats with adjuvant-induced arthritis: involvement of ATP-sensitive K+ channels.
    Neuropharmacology, 2006, Volume: 51, Issue:2

    Topics: Adenosine Triphosphate; Alendronate; Analgesics; Animals; Arthritis, Experimental; Bone Density Cons

2006
Differences in osteoclast formation between proximal and distal tibial osteoporosis in rats with adjuvant arthritis: inhibitory effects of bisphosphonates on osteoclasts.
    Modern rheumatology, 2006, Volume: 16, Issue:6

    Topics: Absorptiometry, Photon; Acid Phosphatase; Alendronate; Animals; Arthritis, Experimental; Bone Densit

2006