alendronate has been researched along with Adenocarcinoma in 4 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we have characterized the cytotoxic reactivity of gammadelta T cell lines established from healthy donors by stimulation with aminobisphosphonate alendronate toward melanoma MeWo and pancreatic adenocarcinomas Colo357 and PancTu1 lines in vitro and in vivo upon adoptive transfer into SCID mice." | 3.72 | Characterization of tumor reactivity of human V gamma 9V delta 2 gamma delta T cells in vitro and in SCID mice in vivo. ( Kabelitz, D; Pitters, E; Wesch, D; Zöller, M, 2004) |
| "Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood." | 1.35 | Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice. ( Härkönen, PL; Tuomela, JM; Väänänen, K; Valta, MP, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinreich, J | 1 |
| Schott, TC | 1 |
| Königsrainer, I | 1 |
| Küper, M | 1 |
| Königsrainer, A | 1 |
| Schott, H | 1 |
| Kabelitz, D | 1 |
| Wesch, D | 1 |
| Pitters, E | 1 |
| Zöller, M | 1 |
| Tuomela, JM | 1 |
| Valta, MP | 1 |
| Väänänen, K | 1 |
| Härkönen, PL | 1 |
| Nemoto, R | 1 |
| Sato, S | 1 |
| Nishijima, Y | 1 |
| Miyakawa, I | 1 |
| Koiso, K | 1 |
| Harada, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420] | Phase 1 | 4 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for alendronate and Adenocarcinoma
| Article | Year |
|---|---|
Cytostatic activity of a 5-fluoro-2'-deoxyuridine-alendronate conjugate against gastric adenocarcinoma and non-malignant intestinal and fibroblast cell lines.
Topics: Adenocarcinoma; Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Cell Line; Cell Line, | 2012 |
Characterization of tumor reactivity of human V gamma 9V delta 2 gamma delta T cells in vitro and in SCID mice in vivo.
Topics: Adenocarcinoma; Adoptive Transfer; Adult; Alendronate; Animals; Cell Line; Cell Line, Tumor; Cell Pr | 2004 |
Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice.
Topics: Adenocarcinoma; Alendronate; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Divi | 2008 |
Effects of a new bisphosphonate (AHBuBP) on osteolysis induced by human prostate cancer cells in nude mice.
Topics: Adenocarcinoma; Alendronate; Animals; Diphosphonates; Etidronic Acid; Humans; Male; Mice; Mice, Nude | 1990 |