alendronate has been researched along with Acroosteolysis with Osteoporosis and Changes in Skull and Mandible in 2 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hajdu-Cheney syndrome (HCS) is a rare autosomal-dominant disorder primarily characterized by acro-osteolysis and early-onset osteoporosis." | 1.48 | High Bone Turnover in Mice Carrying a Pathogenic Notch2 Mutation Causing Hajdu-Cheney Syndrome. ( Amling, M; Cornils, K; Fehse, B; Hermans-Borgmeyer, I; Jeschke, A; Oheim, R; Rolvien, T; Schinke, T; Triviai, I; Vollersen, N; Yorgan, TA, 2018) |
| "Hajdu-Cheney syndrome (HJCYS) is a rare, multisystem bone disease caused by heterozygous mutations in the NOTCH2 gene." | 1.46 | Bone Structural Characteristics and Response to Bisphosphonate Treatment in Children With Hajdu-Cheney Syndrome. ( Clarke, B; Davies, JH; Fratzl-Zelman, N; Gafni, RI; Högler, W; Klaushofer, K; Rauch, F; Roschger, P; Sakka, S; Samuels, M; Saraff, V; Tebben, P, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vollersen, N | 1 |
| Hermans-Borgmeyer, I | 1 |
| Cornils, K | 1 |
| Fehse, B | 1 |
| Rolvien, T | 1 |
| Triviai, I | 1 |
| Jeschke, A | 1 |
| Oheim, R | 1 |
| Amling, M | 1 |
| Schinke, T | 1 |
| Yorgan, TA | 1 |
| Sakka, S | 1 |
| Gafni, RI | 1 |
| Davies, JH | 1 |
| Clarke, B | 1 |
| Tebben, P | 1 |
| Samuels, M | 1 |
| Saraff, V | 1 |
| Klaushofer, K | 1 |
| Fratzl-Zelman, N | 1 |
| Roschger, P | 1 |
| Rauch, F | 1 |
| Högler, W | 1 |
2 other studies available for alendronate and Acroosteolysis with Osteoporosis and Changes in Skull and Mandible
| Article | Year |
|---|---|
High Bone Turnover in Mice Carrying a Pathogenic Notch2 Mutation Causing Hajdu-Cheney Syndrome.
Topics: Adult; Alendronate; Animals; Base Sequence; Bone Diseases, Metabolic; Bone Marrow Cells; Bone Remode | 2018 |
Bone Structural Characteristics and Response to Bisphosphonate Treatment in Children With Hajdu-Cheney Syndrome.
Topics: Adolescent; Alendronate; Bone and Bones; Bone Density; Bone Density Conservation Agents; Calcificati | 2017 |