alendronate has been researched along with Acquired Immunodeficiency Syndrome in 1 studies
alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Bisphosphonates such as alendronate potently inhibit bone resorption and are effective against osteoporosis." | 9.16 | Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120). ( Bentata, M; Costagliola, D; Darasteanu, I; Kolta, S; Lanoy, E; Missy, P; Roux, C; Rozenberg, S; Valantin, MA; Viard, JP, 2012) |
| " Bisphosphonates such as alendronate potently inhibit bone resorption and are effective against osteoporosis." | 5.16 | Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120). ( Bentata, M; Costagliola, D; Darasteanu, I; Kolta, S; Lanoy, E; Missy, P; Roux, C; Rozenberg, S; Valantin, MA; Viard, JP, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rozenberg, S | 1 |
| Lanoy, E | 1 |
| Bentata, M | 1 |
| Viard, JP | 1 |
| Valantin, MA | 1 |
| Missy, P | 1 |
| Darasteanu, I | 1 |
| Roux, C | 1 |
| Kolta, S | 1 |
| Costagliola, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Alendronate Versus Placebo in the Treatment of HIV-1 Associated Osteoporosis, a Multicenter, Randomized, Controlled Trial. ANRS 120 Fosivir[NCT00120757] | Phase 3 | 140 participants | Interventional | 2004-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for alendronate and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120).
Topics: Absorptiometry, Photon; Acquired Immunodeficiency Syndrome; Adult; Alendronate; Anti-HIV Agents; Bon | 2012 |