Page last updated: 2024-11-07

aldosterone and Vascular Diseases

aldosterone has been researched along with Vascular Diseases in 42 studies

Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
" Administration of angiotensin II and Nomega-nitro-L-arginine methyl ester (L-NAME; nitric oxide synthesis inhibitor) to male rats drinking 1% saline caused hypertension, severe biventricular myocardial necrosis, proteinuria, and fibrinoid necrosis of renal and cardiac vessels."7.70Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. ( Adler, GK; Kifor, I; Ochoa-Maya, MR; Rennke, HG; Rocha, R; Stier, CT; Williams, GH, 2000)
"Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study."6.42The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade. ( Davies, JI; Dawson, A; Struthers, AD, 2004)
"Primary aldosteronism not only results in hypertension but also stiffer arteries."5.43Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing adenoma after adrenalectomy: prospective study of 102 patients. ( Chang, YY; Ho, YL; Hung, CS; Liao, CW; Lin, LY; Lin, YH; Lin, YT; Satoh, F; Wang, SM; Wu, KD; Wu, VC, 2016)
"Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)."5.37Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. ( Chen, JW; Chen, YL; Huang, PH; Kuo, CC; Kuo, YS; Lee, BC; Liang, CJ; Lin, SJ; Lin, SL; Lin, YH; Lo, SC; Sun, YY; Tsai, CT; Wu, EL; Wu, KD; Wu, VC, 2011)
" Administration of angiotensin II and Nomega-nitro-L-arginine methyl ester (L-NAME; nitric oxide synthesis inhibitor) to male rats drinking 1% saline caused hypertension, severe biventricular myocardial necrosis, proteinuria, and fibrinoid necrosis of renal and cardiac vessels."3.70Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. ( Adler, GK; Kifor, I; Ochoa-Maya, MR; Rennke, HG; Rocha, R; Stier, CT; Williams, GH, 2000)
"Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study."2.42The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade. ( Davies, JI; Dawson, A; Struthers, AD, 2004)
"The pathophysiology of preeclampsia (PE) remains unclear."1.56An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction. ( Chan, HC; Chen, H; Guo, M; Huang, H; Jin, L; Lin, X; Liu, X; Rahman, TU; Ruan, Y; Sheng, J; Tang, L; Ullah, K; Wang, Y; Wu, D; Wu, Y; Xu, G; Yu, P; Yu, Y; Zhou, C, 2020)
"Microalbuminuria was determined from 24-hour urine collections."1.48Aldosterone as a mediator of microvascular and macrovascular damage in a population of normotensive to early-stage hypertensive individuals. ( Anyfanti, P; Douma, S; Gavriilaki, E; Gkaliagkousi, E; Lazaridis, A; Nikolaidou, B; Triantafyllou, A; Vamvakis, A, 2018)
"Primary aldosteronism not only results in hypertension but also stiffer arteries."1.43Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing adenoma after adrenalectomy: prospective study of 102 patients. ( Chang, YY; Ho, YL; Hung, CS; Liao, CW; Lin, LY; Lin, YH; Lin, YT; Satoh, F; Wang, SM; Wu, KD; Wu, VC, 2016)
"Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)."1.37Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. ( Chen, JW; Chen, YL; Huang, PH; Kuo, CC; Kuo, YS; Lee, BC; Liang, CJ; Lin, SJ; Lin, SL; Lin, YH; Lo, SC; Sun, YY; Tsai, CT; Wu, EL; Wu, KD; Wu, VC, 2011)
"Aldosterone is a steroid hormone that signals through renal mineralocorticoid receptors (MRs) to regulate blood pressure."1.36Placental growth factor mediates aldosterone-dependent vascular injury in mice. ( Aronovitz, M; Carmeliet, P; Ehsan, A; Jaffe, IZ; McGraw, AP; Mendelsohn, ME; Mohammad, NN; Newfell, BG; Perreault, RE, 2010)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199013 (30.95)18.7374
1990's2 (4.76)18.2507
2000's10 (23.81)29.6817
2010's13 (30.95)24.3611
2020's4 (9.52)2.80

Authors

AuthorsStudies
Rivera, A1
Vega, C1
Ramos-Rivera, A1
Maldonado, ER1
Prado, GN1
Karnes, HE1
Fesko, YA1
Snyder, LM1
Alper, SL1
Romero, JR1
Faulkner, JL2
Belin de Chantemèle, EJ2
Kumar, A1
Patel, DR1
Brennan, DM1
Wolski, KE1
Lincoff, AM1
Ruotolo, G1
McErlean, E1
Weerakkody, G1
Riesmeyer, JS1
Nicholls, SJ1
Nissen, SE1
Menon, V1
Lluch, E1
Kennard, S1
Antonova, G1
Jaffe, IZ4
Rodrigues, D1
Costa, TJ1
Silva, JF1
Neto, JTO1
Alves, JV1
Fedoce, AG1
Costa, RM1
Tostes, RC2
Harvey, AP1
Montezano, AC1
Hood, KY1
Lopes, RA1
Rios, F1
Ceravolo, G1
Graham, D1
Touyz, RM1
Gkaliagkousi, E1
Anyfanti, P1
Triantafyllou, A1
Gavriilaki, E1
Nikolaidou, B1
Lazaridis, A1
Vamvakis, A1
Douma, S1
Guo, M1
Zhou, C1
Xu, G1
Tang, L1
Ruan, Y1
Yu, Y1
Lin, X1
Wu, D1
Chen, H1
Yu, P1
Jin, L1
Wang, Y1
Wu, Y1
Ullah, K1
Rahman, TU1
Liu, X1
Sheng, J1
Chan, HC1
Huang, H1
McGraw, AP2
McCurley, A1
Preston, IR1
Lu, ZH1
Zhu, XX1
Tang, ZQ1
Yang, GQ1
Du, J1
Wang, XL1
Yang, JZ1
Gu, WJ1
Guo, QH1
Jin, N1
Yang, LJ1
Ba, JM1
Dou, JT1
Mu, YM1
Liao, CW1
Lin, LY1
Hung, CS1
Lin, YT1
Chang, YY1
Wang, SM1
Wu, VC2
Wu, KD2
Ho, YL1
Satoh, F1
Lin, YH2
Bruder-Nascimento, T1
Ferreira, NS1
Zanotto, CZ1
Ramalho, F1
Pequeno, IO1
Olivon, VC1
Neves, KB1
Alves-Lopes, R1
Campos, E1
Silva, CA1
Fazan, R1
Carlos, D1
Mestriner, FL1
Prado, D1
Pereira, FV1
Braga, T1
Luiz, JP1
Cau, SB1
Elias, PC1
Moreira, AC1
Câmara, NO1
Zamboni, DS1
Alves-Filho, JC1
González-Pérez, P1
Stiefel, P1
Min, LJ1
Mogi, M1
Iwai, M1
Horiuchi, M1
Newfell, BG2
Aronovitz, M1
Mohammad, NN1
Perreault, RE1
Carmeliet, P1
Ehsan, A1
Mendelsohn, ME2
Lo, SC1
Chen, YL1
Huang, PH1
Tsai, CT1
Liang, CJ1
Kuo, CC1
Kuo, YS1
Lee, BC1
Wu, EL1
Sun, YY1
Lin, SL1
Chen, JW1
Lin, SJ1
Luther, JM1
Luo, P1
Wang, Z1
Cohen, SE1
Kim, HS1
Fogo, AB1
Brown, NJ1
Hillaert, MA1
Lentjes, EG1
Kemperman, H1
van der Graaf, Y1
Nathoe, HM1
Beygui, F1
Montalescot, G1
Doevendans, PA1
Wassink, AM1
van Belle, E1
Brem, AS1
Fiebeler, A1
Haller, H1
DAVIS, JO1
PECHET, MM1
BALL, WC1
GOODKIND, MJ1
WARTER, J1
SCHWARTZ, J1
BLOCH, R1
CARA, U1
GIBERTI, A1
BIGLIERI, EG1
SILTANEN, P1
SIPILA, W1
MASSON, GM1
MIKASA, A1
YASUDA, H1
Dawson, A1
Davies, JI1
Struthers, AD2
Tintut, Y1
Demer, LL1
de Solís, AJ1
González-Pacheco, FR1
Deudero, JJ1
Neria, F1
Calabia, O1
Fernández-Sánchez, R1
Caramelo, C1
Xavier, FE1
Aras-López, R1
Arroyo-Villa, I1
del Campo, L1
Salaices, M1
Rossoni, LV1
Ferrer, M1
Balfagón, G1
Kirkendall, WM1
Overturf, ML1
Druilhet, RE1
Van Vliet, AA1
Kröger, R1
Dubbelman, R1
Ten Bokkel-Huinink, WW1
Lajemi, M1
Gautier, S1
Benetos, A1
Duprez, D1
De Buyzere, M1
Rietzschel, ER1
Clement, DL1
Rocha, R1
Stier, CT1
Kifor, I1
Ochoa-Maya, MR1
Rennke, HG1
Williams, GH1
Adler, GK1
Kostiuk, IF1
Suc, JM1
Perez-Stable, EC1
Materson, BJ1
Liddle, GW1
Sims, EA1
MacKay, BR1
Shirai, T1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition With Evacetrapib in Patients at a High-Risk for Vascular Outcomes[NCT01687998]Phase 312,092 participants (Actual)Interventional2012-10-31Terminated (stopped due to Study termination due to insufficient efficacy.)
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055]Phase 475 participants (Anticipated)Interventional2023-08-25Recruiting
A Randomised Open Label, Blinded End Point Trial to Compare the Effects of Spironolactone With Chlortalidone on LV Mass in Stage 3 Chronic Kidney Disease (SPIRO-CKD)[NCT02502981]Phase 4154 participants (Actual)Interventional2014-06-30Active, not recruiting
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?[NCT00291720]Phase 2120 participants (Actual)Interventional2005-04-30Completed
Usefulness of Spironolactone for the Prevention of Acute Kidney Injury in Critically Ill Patients With Invasive Mechanical Ventilation[NCT03206658]Phase 390 participants (Anticipated)Interventional2017-08-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Composite Endpoint of All-Cause Mortality, MI, Stroke, Coronary Revascularization, or Hospitalization for UA

For component endpoints, the number of participants includes those experiencing fatal events and account for all occurrences regardless of whether or not another component event occurred previously. (NCT01687998)
Timeframe: Baseline through End of Study (Up to 4 years)

InterventionParticipants (Count of Participants)
Evacetrapib857
Placebo867

Number of Participants With Composite Endpoint of CV Death, MI, or Coronary Revascularization

For component endpoints, the number of participants includes those experiencing fatal events and account for all occurrences regardless of whether or not another component event occurred previously. (NCT01687998)
Timeframe: Baseline through End of Study (Up to 4 years)

InterventionParticipants (Count of Participants)
Evacetrapib690
Placebo691

Number of Participants With Composite Endpoint of CV Death, MI, Stroke, or Hospitalization for UA

For component endpoints, the number of participants includes those experiencing fatal events and account for all occurrences regardless of whether or not another component event occurred previously. (NCT01687998)
Timeframe: Baseline through End of Study (Up to 4 years)

InterventionParticipants (Count of Participants)
Evacetrapib571
Placebo570

Number of Participants With Composite Primary Endpoint of Cardiovascular (CV) Death, Myocardial Infarction (MI), Stroke, Coronary Revascularization, or Hospitalization for Unstable Angina (UA)

For component endpoints, the number of participants includes those experiencing fatal events and account for all occurrences regardless of whether or not another component event occurred previously. (NCT01687998)
Timeframe: Baseline to Study Completion (Up to 4 years)

InterventionParticipants (Count of Participants)
Evacetrapib779
Placebo776

Number of Participants With Triple Composite Endpoint of CV Death, MI, or Stroke

For component endpoints, the number of participants includes those experiencing fatal events and account for all occurrences regardless of whether or not another component event occurred previously. (NCT01687998)
Timeframe: Baseline through End of Study (Up to 4 years)

InterventionParticipants (Count of Participants)
Evacetrapib437
Placebo453

Mean Percent Change From Baseline to 3 Months in Low-Density (LDL-C) and High-Density Lipoprotein Cholesterol (HDL-C) Levels

(NCT01687998)
Timeframe: Baseline, 3 Months

,
Interventionpercent (Mean)
LDL-CHDL-C
Evacetrapib-31.12133.18
Placebo5.991.63

Reviews

9 reviews available for aldosterone and Vascular Diseases

ArticleYear
Mineralocorticoid Receptor and Endothelial Dysfunction in Hypertension.
    Current hypertension reports, 2019, 09-04, Volume: 21, Issue:10

    Topics: Aldosterone; Animals; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Epithelial S

2019
Mineralocorticoid receptors in vascular disease: connecting molecular pathways to clinical implications.
    Current atherosclerosis reports, 2013, Volume: 15, Issue:7

    Topics: Aldosterone; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Disease Progression;

2013
Signaling mechanisms of angiotensin II in regulating vascular senescence.
    Ageing research reviews, 2009, Volume: 8, Issue:2

    Topics: Aging; Aldosterone; Angiotensin II; Animals; Humans; Receptor, Angiotensin, Type 1; Renin-Angiotensi

2009
Participation of the mineralocorticoid receptor in cardiac and vascular remodeling.
    Nephron. Physiology, 2003, Volume: 94, Issue:3

    Topics: Aldosterone; Animals; Heart Diseases; Humans; Kidney; Mice; Mineralocorticoid Receptor Antagonists;

2003
The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade.
    Expert review of cardiovascular therapy, 2004, Volume: 2, Issue:1

    Topics: Aldosterone; Autonomic Nervous System Diseases; Endomyocardial Fibrosis; Eplerenone; Heart Failure;

2004
Aldosterone-induced vasculopathy.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Aldosterone; Chronic Disease; Death, Sudden, Cardiac; Fibrosis; Heart Arrest; Heart Failure; Humans;

2004
[Rigidity of large arteries and cardiovascular risk. epidemiological aspects and genetic determinants].
    Pathologie-biologie, 1999, Volume: 47, Issue:6

    Topics: Aldosterone; Arteries; Cardiovascular Diseases; Elasticity; Humans; Renin-Angiotensin System; Risk F

1999
Aldosterone and vascular damage.
    Current hypertension reports, 2000, Volume: 2, Issue:3

    Topics: Adrenal Cortex; Aldosterone; Arteries; Autonomic Nervous System; Baroreflex; Body Water; Compliance;

2000
[Malignant arterial hypertension].
    La Nouvelle presse medicale, 1975, Mar-08, Volume: 4, Issue:10

    Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Endarteritis; Female; Humans; Hypertension, Ma

1975

Trials

3 trials available for aldosterone and Vascular Diseases

ArticleYear
Blockade of the mineralocorticoid receptor improves markers of human endothelial cell dysfunction and hematological indices in a mouse model of sickle cell disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:8

    Topics: Aldosterone; Anemia, Sickle Cell; Animals; Disease Models, Animal; Endothelial Cells; Endothelin-1;

2023
Plasma Aldosterone Levels Are Not Associated With Cardiovascular Events Among Patients With High-Risk Vascular Disease: Insights From the ACCELERATE Trial.
    Journal of the American Heart Association, 2019, 12-03, Volume: 8, Issue:23

    Topics: Aged; Aldosterone; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Double-Blind

2019
Treatment of patients with IVCS and gross oedema and ascites with diuretic combination and ACE-inhibitors: relation to baseline PRA and PAC.
    The Netherlands journal of medicine, 1995, Volume: 46, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Ascites; Captopril; Diuretics; D

1995

Other Studies

30 other studies available for aldosterone and Vascular Diseases

ArticleYear
Selective deletion of endothelial mineralocorticoid receptor protects from vascular dysfunction in sodium-restricted female mice.
    Biology of sex differences, 2020, 11-23, Volume: 11, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Cyclooxygenase 2; Cytochrome P-450 CYP11B2; Diet, Sodium-Restr

2020
Aldosterone Negatively Regulates Nrf2 Activity: An Additional Mechanism Contributing to Oxidative Stress and Vascular Dysfunction by Aldosterone.
    International journal of molecular sciences, 2021, Jun-07, Volume: 22, Issue:11

    Topics: Aldosterone; Animals; Endothelium, Vascular; Kelch-Like ECH-Associated Protein 1; Male; Mice; Mice,

2021
Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: The aldosterone-mineralocorticoid receptor-Nox1 axis.
    Life sciences, 2017, Jun-15, Volume: 179

    Topics: Acetylcholine; Aldosterone; Animals; Aorta; Blood Pressure; Galectin 3; Hypertension; Male; Mesenter

2017
Aldosterone as a mediator of microvascular and macrovascular damage in a population of normotensive to early-stage hypertensive individuals.
    Journal of the American Society of Hypertension : JASH, 2018, Volume: 12, Issue:1

    Topics: Adult; Albuminuria; Aldosterone; Blood Pressure; Correlation of Data; Female; Humans; Hypertension;

2018
An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction.
    Science China. Life sciences, 2020, Volume: 63, Issue:3

    Topics: Adult; Aldosterone; Alternative Splicing; Blood Pressure; DNA, Complementary; Endothelial Cells; Fem

2020
Female sex hormones are associated with the reduction of serum sodium and hypertension complications in patients with aldosterone-producing adenoma.
    Endocrine journal, 2013, Volume: 60, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Biomarkers; Cerebrovascular Disorders;

2013
Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing adenoma after adrenalectomy: prospective study of 102 patients.
    Scientific reports, 2016, Feb-17, Volume: 6

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Ankle Brachial Index; Female; Hemodynamics; Humans; Hype

2016
NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage.
    Circulation, 2016, Dec-06, Volume: 134, Issue:23

    Topics: Acetylcholine; Aldosterone; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Caspase 1; Huma

2016
Increased carotid intima-media thickness in hypertensive patients with a high aldosterone/plasma renin activity ratio and elevated aldosterone plasma concentration.
    Journal of hypertension, 2008, Volume: 26, Issue:7

    Topics: Aldosterone; Carotid Arteries; Humans; Hypertension; Renin; Tunica Intima; Tunica Media; Ultrasonogr

2008
Placental growth factor mediates aldosterone-dependent vascular injury in mice.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:11

    Topics: Aldosterone; Animals; Atherosclerosis; Blood Vessels; Clinical Trials as Topic; Humans; Male; Mice;

2010
Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10

    Topics: Adenoma; Adult; Aged; Aldosterone; Apoptosis; Arteries; Biomarkers; C-Reactive Protein; Cell Count;

2011
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.
    Kidney international, 2012, Volume: 82, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Aorta; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; D

2012
Aldosterone, atherosclerosis and vascular events in patients with stable coronary artery disease.
    International journal of cardiology, 2013, Sep-01, Volume: 167, Issue:5

    Topics: Aged; Aldosterone; Atherosclerosis; Biomarkers; Cohort Studies; Coronary Artery Disease; Female; Fol

2013
Targeting activated mineralocorticoid receptor: Occam's razor revisited.
    Kidney international, 2012, Volume: 82, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Heart Diseases; Kidney Diseases; Mineralocorticoid Receptor An

2012
Increased aldosterone secretion in dogs with right-sided congestive heart failure and in dogs with thoracic inferior vena cava constriction.
    The Journal of clinical investigation, 1957, Volume: 36, Issue:5

    Topics: Aldosterone; Animals; Constriction; Constriction, Pathologic; Dogs; Heart Failure; Vascular Diseases

1957
[Secondary hyperaldosteronism in the course of arterial hypertension].
    La Presse medicale, 1960, Jan-02, Volume: 68

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Vascular Diseases

1960
[Mineralo-corticoid activity in arteriopathic patients subjected to lumbar gangliectomy].
    Rivista di patologia e clinica, 1962, Volume: 17

    Topics: Adrenal Cortex Hormones; Aldosterone; Arteriosclerosis Obliterans; Humans; Lumbosacral Region; Sympa

1962
HYPOKALEMIC ALKALOSIS EDEMA WITH INCREASED DESOXYCORTICOSTERONE EXCRETION.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: Adrenalectomy; Aldosterone; Alkalosis; Angiotensins; Bartter Syndrome; Blood Volume; Cushing Syndrom

1965
Hypertension associated with hypokalemia and alkalosis simulating primary hyperaldosteronism: report of a case.
    Annales medicinae internae Fenniae, 1959, Volume: 48

    Topics: Aldosterone; Alkalosis; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Potassium; Vascular D

1959
Experimental vascular disease elicited by aldosterone and renin.
    Endocrinology, 1962, Volume: 71

    Topics: Aldosterone; Angiotensin Amide; Blood Vessels; Disease; Humans; Hypertension; Renin; Vascular Diseas

1962
Mineralocorticoid receptor activation promotes vascular cell calcification.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Aldosterone; Alkaline Phosphat

2007
[Aldosterone increases in vitro vascular calcification].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2008, Volume: 28, Issue:2

    Topics: Aldosterone; Calcinosis; Cells, Cultured; Humans; Muscle, Smooth, Vascular; Vascular Diseases

2008
Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A2 and prostacyclin.
    British journal of pharmacology, 2008, Volume: 154, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aldosterone; Animals; Blotting,

2008
Is renin a risk factor?
    Transactions of the American Clinical and Climatological Association, 1981, Volume: 92

    Topics: Aldosterone; Animals; Aortic Diseases; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Hy

1981
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibi

2000
[Humoral pressor and depressor factors in vibration disease].
    Gigiena truda i professional'nye zabolevaniia, 1976, Issue:4

    Topics: Adult; Aldosterone; Animals; Catecholamines; Circadian Rhythm; Humans; Kininogens; Middle Aged; Neur

1976
Workup of the newly discovered hypertensive patient.
    Postgraduate medicine, 1975, Volume: 57, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Cardiac Output; Cerebrovascular Disorders; Contraceptives, Oral;

1975
Idiopathic oedema.
    Lancet (London, England), 1972, Jun-24, Volume: 1, Issue:7765

    Topics: Adrenal Glands; Aldosterone; Diuretics; Edema; Female; Gonadal Steroid Hormones; Humans; Plasma Volu

1972
Proceedings: Blueprints for the solution of three endocrinological enigmas. The Sir Henry Dale Lecture for 1973.
    The Journal of endocrinology, 1973, Volume: 59, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Blood Glucose; Ca

1973
The relation of capillary angiopathy and diabetes mellitus to idiopathic edema.
    Annals of internal medicine, 1965, Volume: 63, Issue:6

    Topics: Adult; Aldosterone; Basement Membrane; Blood Chemical Analysis; Capillaries; Capillary Permeability;

1965