Page last updated: 2024-11-07

aldosterone and Syncope

aldosterone has been researched along with Syncope in 11 studies

Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Research Excerpts

ExcerptRelevanceReference
"Rates of presyncope were 38% with no drug; 0% with midodrine alone; 100% with promethazine alone; and 63% with both drugs."3.77Effects of promethazine and midodrine on orthostatic tolerance. ( Meck, JV; Platts, SH; Shi, SJ; Ziegler, MG, 2011)
"Using passive 4-min 70° head-up tilt followed by 4-min sequences of additional lower body negative pressure of increasing intensity (15 mmHg steps), presyncope occurred after 11·6 ± 2·8 min, at which time plasma volume was reduced by 15·5 ± 7·4%, aldosterone increased by 37%, ACTH by 75%, PRA by 187% and AVP about 16-fold in average (all P < 0·01); no significant changes in adrenomedullin were seen."3.77Hormonal and plasma volume changes after presyncope. ( Goswami, N; Hinghofer-Szalkay, H; Jantscher, A; Lackner, HK; Narath, B; Rössler, A, 2011)
"Cases of PA with malignant arrhythmia as the first symptom have been reported."1.48Aldosteronism with mild hypokalemia presenting as life-threatening ventricular arrhythmias: A case report. ( Cai, Q; Li, H; Shao, D; Wang, S; Zhang, R; Zhang, Z; Zheng, Y; Zhou, S, 2018)
"Patients with vasodepressor syncope had a significant rise in renin (9."1.30Different humoral responses during head-up tilt testing among patients with neurocardiogenic syncope. ( Andries, E; Brugada, P; Goethals, M; Nellens, P; Vanderheyden, M, 1998)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shao, D1
Wang, S1
Zhou, S1
Cai, Q1
Zhang, R1
Li, H1
Zheng, Y1
Zhang, Z1
Wagoner, AL1
Shaltout, HA1
Fortunato, JE1
Diz, DI1
Shi, SJ1
Platts, SH1
Ziegler, MG1
Meck, JV1
Hinghofer-Szalkay, H1
Lackner, HK1
Rössler, A2
Narath, B1
Jantscher, A1
Goswami, N1
LAMBREW, CT1
CARVER, ST1
PETERSON, RE1
HORWITH, M1
BOTTICELLI, JT1
LANGE, RL1
KELLY, OA1
Garland, EM1
Raj, SR1
Black, BK1
Harris, PA1
Robertson, D1
Vanderheyden, M1
Goethals, M1
Nellens, P1
Andries, E1
Brugada, P1
László, Z1
Hinghofer-Szalkay, HG1
Wolthuis, RA1
Bergman, SA1
Nicogossian, AE1
Marek, J1
Horký, K1
Küchel, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Estimating the Frequency and Neuro-Hormonal Characteristics of Acute Hepatic Porphyria in Postural Tachycardia Syndrome[NCT05344599]50 participants (Anticipated)Observational2022-01-19Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aldosterone and Syncope

ArticleYear
Physiological effects of locally applied reduced pressure in man.
    Physiological reviews, 1974, Volume: 54, Issue:3

    Topics: Aldosterone; Atmospheric Pressure; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Output; Cen

1974

Trials

1 trial available for aldosterone and Syncope

ArticleYear
The hemodynamic and neurohumoral phenotype of postural tachycardia syndrome.
    Neurology, 2007, Aug-21, Volume: 69, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Autonomic Nervous System Diseases; Biomarkers; Blood Pressure; Catec

2007

Other Studies

9 other studies available for aldosterone and Syncope

ArticleYear
Aldosteronism with mild hypokalemia presenting as life-threatening ventricular arrhythmias: A case report.
    Medicine, 2018, Volume: 97, Issue:50

    Topics: Aged; Aldosterone; Arrhythmias, Cardiac; China; Electrocardiography; Humans; Hyperaldosteronism; Hyp

2018
Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options.
    American journal of physiology. Heart and circulatory physiology, 2016, Feb-01, Volume: 310, Issue:3

    Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Arterial Pressure; Blood Press

2016
Effects of promethazine and midodrine on orthostatic tolerance.
    Aviation, space, and environmental medicine, 2011, Volume: 82, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adult; Aldosterone; Blood Pressure; Cardiac Output; Diastole;

2011
Hormonal and plasma volume changes after presyncope.
    European journal of clinical investigation, 2011, Volume: 41, Issue:11

    Topics: Adrenocorticotropic Hormone; Adrenomedullin; Adult; Aldosterone; Head-Down Tilt; Humans; Male; Plasm

2011
Hypoaldosteronism as a cause of hyperkalemia and syncopal attacks in a patient with complete heart block.
    The American journal of medicine, 1961, Volume: 31

    Topics: Aldosterone; Atrioventricular Block; Cardiovascular Diseases; Heart Block; Humans; Hyperkalemia; Hyp

1961
POSTURAL HYPOTENSION WITH DECREASED CENTRAL BLOOD VOLUME AND IMPAIRED ALDOSTERONE RESPONSE.
    The American journal of medicine, 1964, Volume: 37

    Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Blood Pressure Determination; Blood Volume; Bloo

1964
Different humoral responses during head-up tilt testing among patients with neurocardiogenic syncope.
    American heart journal, 1998, Volume: 135, Issue:1

    Topics: Adult; Aldosterone; Epinephrine; Female; Hemodynamics; Humans; Male; Middle Aged; Norepinephrine; Re

1998
Cardiovascular and humoral readjustment after different levels of head-up tilt in humans.
    Aviation, space, and environmental medicine, 2001, Volume: 72, Issue:3

    Topics: Adult; Aldosterone; Dizziness; Epinephrine; Gravitation; Hemodynamics; Humans; Hydrocortisone; Lower

2001
[Orthostatic reaction disorders in the etiopathogenesis of various pathologic conditions].
    Casopis lekaru ceskych, 1970, Mar-06, Volume: 109, Issue:11

    Topics: Addison Disease; Aldosterone; Edema; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Hypote

1970