Page last updated: 2024-11-07

aldosterone and Nephrosclerosis

aldosterone has been researched along with Nephrosclerosis in 16 studies

Nephrosclerosis: Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
" In this study, we conducted an open-label and randomized trial to compare the effects of benidipine with those of amlodipine on blood pressure (BP), albuminuria and aldosterone concentration in hypertensive patients with mild-to-moderate stage chronic kidney disease (CKD)."9.15Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria. ( Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M, 2011)
" In this study, we conducted an open-label and randomized trial to compare the effects of benidipine with those of amlodipine on blood pressure (BP), albuminuria and aldosterone concentration in hypertensive patients with mild-to-moderate stage chronic kidney disease (CKD)."5.15Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria. ( Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M, 2011)
"Hypertensive nephrosclerosis is characterized by activation of the renin-angiotensin-aldosterone system in combination with an inflammatory response characterized by an infiltration of T-cells and mononuclear cells, which release proinflammatory cytokines like IL-1beta/TNFalpha."1.35Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells. ( Gauer, S; Geiger, H; Goppelt-Struebe, M; Hauser, IA; Holzmann, Y; Obermüller, N, 2008)
"Aldosterone levels were unresponsive to variations in dietary salt intake and plasma renin activity was suppressed."1.26Dexamethasone suppressible hyperaldosteronism in a child with nephrosclerosis. ( Lee, SM; Levine, L; Lightner, E; New, MI; Oberfield, S; Witte, M, 1982)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Sawamura, M1
Sawa, N1
Oshima, Y1
Ikuma, D1
Yamanouchi, M1
Hayami, N1
Sekine, A1
Mizuno, H1
Hasegawa, E1
Suwabe, T1
Hoshino, J1
Kono, K1
Kinowaki, K1
Ohashi, K1
Ubara, Y1
Zhou, X1
Fukuda, N1
Matsuda, H1
Endo, M1
Wang, X1
Saito, K1
Ueno, T1
Matsumoto, T1
Matsumoto, K2
Soma, M2
Kobayashi, N1
Nishiyama, A1
Remuzzi, G1
Cattaneo, D1
Perico, N1
Abe, M1
Okada, K1
Maruyama, N1
Matsumoto, S1
Maruyama, T1
Fujita, T1
Lee, JH1
Kim, JH1
Kim, JS1
Chang, JW1
Kim, SB1
Park, JS1
Lee, SK1
LARAGH, JH2
CANNON, PJ1
AMES, RP1
KELLY, WG1
HALL, CE1
HALL, O1
Van Den Meiracker, AH1
Huizenga, AT1
Boomsma, F1
Gauer, S1
Hauser, IA1
Obermüller, N1
Holzmann, Y1
Geiger, H1
Goppelt-Struebe, M1
Muller, DN1
Klanke, B1
Feldt, S1
Cordasic, N1
Hartner, A1
Schmieder, RE1
Luft, FC1
Hilgers, KF1
Lee, SM1
Lightner, E1
Witte, M1
Oberfield, S1
Levine, L1
New, MI1
Sparano, F1
Sciarra, F1
Sulon, J1
Giaquinto, G1
Mercuri, MA1
Odoardi, A1
Tosticroce, C1
Genard, P1
Conti, C1
Girndt, J1
Berman, LB1
Vertes, V1
Castleman, B1
Scully, RE1
McNeely, BU1

Reviews

3 reviews available for aldosterone and Nephrosclerosis

ArticleYear
ALDOSTERONE: ITS BIOCHEMISTRY AND PHYSIOLOGY.
    Advances in metabolic disorders, 1964, Volume: 15

    Topics: Aldosterone; Angiotensins; Biochemical Phenomena; Biochemistry; Blood; Edema; Female; Homeostasis; H

1964
[Profibrotic effects of aldosterone].
    Nederlands tijdschrift voor geneeskunde, 2004, Jul-31, Volume: 148, Issue:31

    Topics: Aldosterone; Animals; Fibrosis; Heart Diseases; Humans; Mineralocorticoid Receptor Antagonists; Myoc

2004
The pathophysiology of renin.
    Clinical symposia (Summit, N.J. : 1957), 1973, Volume: 25, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal;

1973

Trials

1 trial available for aldosterone and Nephrosclerosis

ArticleYear
Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:2

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calciu

2011

Other Studies

12 other studies available for aldosterone and Nephrosclerosis

ArticleYear
A case of malignant nephrosclerosis occurring with serum renin in the normal range.
    CEN case reports, 2023, Volume: 12, Issue:1

    Topics: Adult; Aldosterone; Humans; Hypertension; Male; Nephrosclerosis; Reference Values; Renin

2023
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice.
    American journal of physiology. Renal physiology, 2013, Oct-01, Volume: 305, Issue:7

    Topics: Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Complement C3; Epithelial-Mes

2013
The aggravating mechanisms of aldosterone on kidney fibrosis.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:8

    Topics: Aldosterone; Fibrosis; Humans; Kidney; Nephrosclerosis; Renin-Angiotensin System

2008
AMP-activated protein kinase inhibits TGF-β-, angiotensin II-, aldosterone-, high glucose-, and albumin-induced epithelial-mesenchymal transition.
    American journal of physiology. Renal physiology, 2013, Mar-15, Volume: 304, Issue:6

    Topics: Albumins; Aldosterone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Ce

2013
INTERACTION BETWEEN ALDOSTERONE SECRETION, SODIUM AND POTASSIUM BALANCE, AND ANGIOTENSIN ACTIVITY IN MAN: STUDIES IN HYPERTENSION AND CIRRHOSIS.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Blood Pressure; Edema; Humans; Hyperaldosteronism; Hypert

1964
HYPERTENSION AND HYPERSALIMENTATION. I. ALDOSTERONE HYPERTENSION.
    Laboratory investigation; a journal of technical methods and pathology, 1965, Volume: 14

    Topics: Adrenal Glands; Aldosterone; Arteritis; Diet; Heart Diseases; Hypertension; Kidney; Metabolism; Myoc

1965
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Aldosterone; Animals; Chemotaxis, Leukocyte; Drug Synergism; Hypertension; Interleukin-1beta; Mesang

2008
(Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Renovascul

2008
Dexamethasone suppressible hyperaldosteronism in a child with nephrosclerosis.
    Acta endocrinologica, 1982, Volume: 99, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Dexamethasone; Glomerulonephritis; Humans; Hyperald

1982
Diurnal 18-hydroxy-11-deoxycorticosterone pattern in human stable hypertension.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adult; Aldosterone; Circadian Rhythm; Cushing Syndrome;

1978
[Oral contraceptives, hypertension and nephrosclerosis].
    Fortschritte der Medizin, 1978, Feb-16, Volume: 96, Issue:7

    Topics: Adult; Aldosterone; Animals; Blood Coagulation; Contraceptives, Oral; Estrogens; Female; Humans; Hyp

1978
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1972.
    The New England journal of medicine, 1972, Sep-28, Volume: 287, Issue:13

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis, Di

1972