aldosterone has been researched along with Myocarditis in 10 studies
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, tempol failed to suppress cardiac hypertrophy, the formation of inflammatory lesions, and upregulation of cardiac MCP-1 and osteopontin by aldosterone, while N-acetylcysteine could inhibit all of them." | 5.33 | Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress. ( Iwao, H; Izumi, Y; Izumiya, Y; Kim-Mitsuyama, S; Ueda, M; Wake, R; Yoshida, K; Yoshiyama, M; Yukimura, T, 2005) |
| "However, tempol failed to suppress cardiac hypertrophy, the formation of inflammatory lesions, and upregulation of cardiac MCP-1 and osteopontin by aldosterone, while N-acetylcysteine could inhibit all of them." | 1.33 | Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress. ( Iwao, H; Izumi, Y; Izumiya, Y; Kim-Mitsuyama, S; Ueda, M; Wake, R; Yoshida, K; Yoshiyama, M; Yukimura, T, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cardona, A | 1 |
| Baker, P | 1 |
| Kahwash, R | 1 |
| Smart, S | 1 |
| Phay, JE | 1 |
| Basso, C | 1 |
| Raman, SV | 1 |
| Heier, CR | 1 |
| Yu, Q | 1 |
| Fiorillo, AA | 1 |
| Tully, CB | 1 |
| Tucker, A | 1 |
| Mazala, DA | 1 |
| Uaesoontrachoon, K | 1 |
| Srinivassane, S | 1 |
| Damsker, JM | 1 |
| Hoffman, EP | 1 |
| Nagaraju, K | 1 |
| Spurney, CF | 1 |
| Yasuoka, S | 1 |
| Kai, H | 1 |
| Kajimoto, H | 1 |
| Kudo, H | 1 |
| Takayama, N | 1 |
| Anegawa, T | 1 |
| Koga, M | 1 |
| Miyamoto, T | 1 |
| Mifune, H | 1 |
| Kage, M | 1 |
| Hirooka, Y | 1 |
| Imaizumi, T | 1 |
| Hattori, T | 1 |
| Murase, T | 1 |
| Sugiura, Y | 1 |
| Nagasawa, K | 1 |
| Takahashi, K | 1 |
| Ohtake, M | 2 |
| Miyachi, M | 1 |
| Murohara, T | 1 |
| Nagata, K | 1 |
| Rickard, AJ | 1 |
| Morgan, J | 1 |
| Chrissobolis, S | 1 |
| Miller, AA | 1 |
| Sobey, CG | 1 |
| Young, MJ | 1 |
| Westcott, KV | 1 |
| Huang, BS | 1 |
| Leenen, FH | 1 |
| SANDERS, LL | 1 |
| MELBY, JC | 1 |
| Yoshida, K | 1 |
| Kim-Mitsuyama, S | 1 |
| Wake, R | 1 |
| Izumiya, Y | 1 |
| Izumi, Y | 1 |
| Yukimura, T | 1 |
| Ueda, M | 1 |
| Yoshiyama, M | 1 |
| Iwao, H | 1 |
| Neves, MF | 1 |
| Amiri, F | 1 |
| Virdis, A | 1 |
| Diep, QN | 1 |
| Schiffrin, EL | 1 |
| Fraccarollo, D | 1 |
| Galuppo, P | 1 |
| Schraut, S | 1 |
| Kneitz, S | 1 |
| van Rooijen, N | 1 |
| Ertl, G | 1 |
| Bauersachs, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Open-Label, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy of Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)[NCT05185622] | Phase 2 | 54 participants (Anticipated) | Interventional | 2022-03-21 | Recruiting | ||
| A Phase II Pilot Trial of Vamorolone vs. Placebo for the Treatment of Becker Muscular Dystrophy[NCT05166109] | Phase 2 | 39 participants (Anticipated) | Interventional | 2022-07-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aldosterone and Myocarditis
| Article | Year |
|---|---|
Brain renin-angiotensin-aldosterone system and ventricular remodeling after myocardial infarct: a review.
Topics: Aldosterone; Animals; Apoptosis; Brain; Humans; Myocardial Infarction; Myocarditis; Myocytes, Cardia | 2009 |
9 other studies available for aldosterone and Myocarditis
| Article | Year |
|---|---|
Evidence of aldosterone synthesis in human myocardium in acute myocarditis.
Topics: Acute Disease; Adult; Aldosterone; Biomarkers; Biopsy; Female; Humans; Immunohistochemistry; Male; M | 2019 |
Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Cardiomyopathies; Computer Simulation; CRISPR-Associ | 2019 |
Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Cardiomyopathies; Computer Simulation; CRISPR-Associ | 2019 |
Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Cardiomyopathies; Computer Simulation; CRISPR-Associ | 2019 |
Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Cardiomyopathies; Computer Simulation; CRISPR-Associ | 2019 |
Blood pressure variability activates cardiac mineralocorticoid receptor and induces cardiac remodeling in hypertensive rats.
Topics: Active Transport, Cell Nucleus; Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cell Nucleus; Ep | 2013 |
Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Echocardiography; Endoth | 2014 |
Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure.
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cells, Cultured; Conne | 2014 |
ALDOSTERONE AND THE EDEMA OF CONGESTIVE HEART FAILURE.
Topics: Aldosterone; Chromatography; Diuretics; Edema; Geriatrics; Heart Diseases; Heart Failure; Hypertensi | 1964 |
Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress.
Topics: Acetylcysteine; Aldosterone; Animals; Blood Pressure; Cardiomegaly; Chemokine CCL2; Echocardiography | 2005 |
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Collagen; Ectodysplasins; Fibrosis; Heart; Hypertension | 2005 |
Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response.
Topics: Aldosterone; Animals; Clodronic Acid; Collagen; Cytokines; Eplerenone; Factor XIIIa; Heart Failure; | 2008 |