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aldosterone and Myocardial Infarction

aldosterone has been researched along with Myocardial Infarction in 192 studies

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
"Of patients with acute myocardial infarction eligible for the International Study of Infarct Survival-4, randomized to captopril (n = 30) or placebo (n = 33), the captopril group had a significant decrease in blood adrenaline on day 3 compared with baseline values."9.08Effect of early captopril treatment on blood adrenaline levels in acute myocardial infarction (the substudy of ISIS-4). International Study of Infarct Survival-4. ( Budaj, A; Ceremuzyński, L; Herbaczyńska-Cedro, K; Kokot, F, 1998)
"A 12 week randomised, double blind, placebo controlled study on the effect of enalapril (5-20 mg daily) on the concentration of plasma atrial natriuretic peptide level and activity of the sympathetic nervous system and renin angiotensin system was done on 27 patients who had suffered an uncomplicated acute myocardial infarction two to six months earlier."9.07Effect of enalapril on plasma atrial natriuretic peptide in late recovery phase of acute myocardial infarction. ( Hirvonen, T; Mustonen, J; Pyörälä, K; Remes, J; Tenhunen, M; Tikkanen, I, 1991)
"Plasma neurohormones were sequentially analysed in 98 patients with acute myocardial infarction randomized to treatment with enalapril or placebo for 4-6 months."9.07Neurohormonal effects of early treatment with enalapril after acute myocardial infarction and the impact on left ventricular remodelling. ( Held, P; Sigurdsson, A; Swedberg, K; Wall, B, 1993)
" More recently, the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study has provided firm support for the use of eplerenone (Inspra, Pfizer) in heart failure following acute myocardial infarction in addition to neurohormonal blockade with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and beta-blockers."8.82Eplerenone in the treatment of chronic heart failure. ( Krum, H; Liew, D, 2004)
"Both aldosterone and arginine vasopressin (AVP) are produced in the heart and may participate in cardiac fibrosis."8.12Phosphorylation of CaMK and CREB-Mediated Cardiac Aldosterone Synthesis Induced by Arginine Vasopressin in Rats with Myocardial Infarction. ( Gao, X; Li, J; Lu, G; Peng, L; Zhai, YS, 2022)
"To address this question, we examined data from the dal-OUTCOMES trial that compared the cholesteryl ester transfer protein inhibitor dalcetrapib with placebo, beginning 4 to 12 weeks after an index acute coronary syndrome."7.85Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. ( Ballantyne, CM; Barter, PJ; Gunzburger, E; Kallend, D; Kittelson, J; Leiter, LA; Leitersdorf, E; McMurray, JJ; Nicholls, SJ; Olsson, AG; Pitts, R; Schwartz, GG; Shah, PK; Tardif, JC, 2017)
" We investigated the effects of adding the direct renin inhibitor (DRI), aliskiren, to an ACEI or an ARB on monocyte subsets and myocardial salvage in patients with primary acute myocardial infarction (AMI)."7.78Effect of direct renin inhibitor, aliskiren, on peripheral blood monocyte subsets and myocardial salvage in patients with primary acute myocardial infarction. ( Akasaka, T; Imanishi, T; Ino, Y; Ishibashi, K; Kashiwagi, M; Kitabata, H; Komukai, K; Orii, M; Ozaki, Y; Shimamura, K; Shiono, Y; Sougawa, H; Tanimoto, T; Tsujioka, H, 2012)
"Losartan may reduce reactive fibrosis not only by attenuating the Ald signaling pathway but also by decreasing the expression of MR."7.74[Mechanisms of losartan for inhibition of myocardial fibrosis following myocardial infarction in rats]. ( Bai, SC; Deng, LH; Huang, P; Su, L; Wen, YW; Wu, ZL; Xu, DL, 2008)
"Eplerenone, a selective aldosterone blocker, has been shown to attenuate cardiac fibrosis and decrease cardiovascular events in both experimental and clinical studies."7.73Effects of eplerenone and salt intake on left ventricular remodeling after myocardial infarction in rats. ( Abe, Y; Izumi, T; Mochizuki, S; Taniguchi, I; Urabe, A, 2006)
" The aim of the present study was to evaluate the role of aldosterone and angiotensin II on formation of left ventricular fibrosis induced by chronic beta-adrenergic stimulation with isoproterenol (iso) in the rat heart failure model induced by myocardial infarction (MI)."7.73Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist. ( Bos, R; Findji, L; Lechat, P; Médiani, O; Mougenot, N; Vanhoutte, PM, 2005)
"The aim of this study was to assess the effects of the Na+-H+ exchange inhibitor cariporide on left ventricular (LV) morphology and function as well as inflammation in rabbits with heart failure."7.72Inhibition of Na+-H+ exchange by cariporide reduces inflammation and heart failure in rabbits with myocardial infarction. ( Busch, AE; Gerl, M; Licher, T; Ruetten, H; Rungwerth, K; Schäfer, S; Schindler, U, 2004)
"Adrenomedullin (AM) is expressed in cardiac tissue, and plasma AM levels increase in patients with acute myocardial infarction (MI)."7.72Adrenomedullin administration immediately after myocardial infarction ameliorates progression of heart failure in rats. ( Asada, Y; Cao, Y; Eto, T; Imamura, T; Kangawa, K; Kato, J; Kitamura, K; Marutsuka, K; Nakamura, R; Onitsuka, H, 2004)
"Oral administration of spironolactone improves cardiac remodeling and its central infusion prevents the increase in sympathetic drive post-myocardial infarction (MI)."7.72Critical role of CNS effects of aldosterone in cardiac remodeling post-myocardial infarction in rats. ( Lal, A; Leenen, FH; Veinot, JP, 2004)
"Canrenone attenuates LV interstitial remodeling and reduces filling pressures in rats with postinfarction heart failure."7.71Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. ( Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M, 2002)
" This increase is mediated primarily by cardiac angiotensin II via AT1-subtype receptor and may be involved in post-MI ventricular fibrosis and in control of tissue norepinephrine concentration."7.70Activation of cardiac aldosterone production in rat myocardial infarction: effect of angiotensin II receptor blockade and role in cardiac fibrosis. ( Aupetit-Faisant, B; Carayon, A; Delcayre, C; Heymes, C; Oubénaïssa, A; Robert, V; Silvestre, JS; Swynghedauw, B, 1999)
"The effect of enalapril during healing between 1 day and 6 weeks after myocardial infarction on in vivo changes in ventricular size, shape, mass, and function (asynergy, or akinesis and dyskinesis, and ejection fraction), as determined by serial two-dimensional echocardiography, hemodynamics, postmortem topography (planimetered short- and long-axis ventricular contours), and collagen content (determined by levels of hydroxyproline, a marker for collagen), was measured in 25 instrumented dogs."7.69Effect of enalapril on ventricular remodeling and function during healing after anterior myocardial infarction in the dog. ( Blinston, GE; Jugdutt, BI; Jugdutt, SJ; Khan, MI, 1995)
"Plasma atrial natriuretic factor (ANF), renin activity (PRA), aldosterone and antidiuretic hormone (ADH) were determined in 16 patients with uncomplicated acute myocardial infarction (AMI) for 7 days in all patients and in six patients for 8 more days."7.68Plasma atrial natriuretic factor in patients with acute myocardial infarction. ( Bernardi, P; Capelli, M; Fontana, F; Spagnolo, N, 1990)
"Plasma atrial natriuretic factor, aldosterone, renin activity, and antidiuretic hormone were studied in low output heart failure syndromes: cardiogenic shock in ten patients with acute myocardial infarction of the anterior wall (first group), hypovolemic shock after melena from peptic ulcer in ten subjects (second group), and hypotension with bradycardia syndrome in ten patients with acute myocardial infarction of the inferior wall (third group)."7.68Plasma atrial natriuretic factor in low output heart failure syndromes. ( Bernardi, P; Capelli, M; Fontana, F; Spagnolo, N, 1990)
"A serial measurements of plasma renin activity (PRA), serum angiotensin converting enzyme activity (ACE), concentrations of plasma angiotensin II (AII) and plasma aldosterone (Ald) in 38 consecutive patients with acute myocardial infarction (AMI) or suspected AMI showed that PRA, AII and Ald levels increased in patients with AMI, especially within first week after onset, and were significantly higher in those cases with severe complications."7.68[The changes in renin-angiotensin-aldosterone system in acute myocardial infarction and the effects of converting enzyme inhibitor-captopril]. ( Jiang, M, 1991)
"Plasma atrial natriuretic factor (ANF) levels were measured in 29 patients who had normal atrial hemodynamics on days 4 and 8 after an uncomplicated acute myocardial infarction (AMI)."7.68Plasma atrial natriuretic factor in uncomplicated acute myocardial infarction. ( Antonopoulos, A; Aspiotis, N; Kyriakidis, M; Marakas, S; Petropoulakis, P; Toutouzas, P; Tselika, C, 1993)
"The aim of this paper was to study plasma atrial natriuretic factor, renin activity, aldosterone and antidiuretic hormone in low-output heart failure syndromes such as cardiogenic shock, hypovolemic shock and hypotension with bradycardia syndrome."7.67[Atrial natriuretic factor in cardiogenic shock, in hypovolemic shock and in the bradycardia-hypotension syndrome following acute myocardial infarction]. ( Bernardi, P; Capelli, M; Fontana, F; Spagnolo, N, 1989)
"The angiotensin-converting enzyme inhibitor, captopril, was given to 19 patients with severe heart failure."7.66Effects of captopril in acute and chronic heart failure. Correlations with plasma levels of noradrenaline, renin, and aldosterone. ( Boomsma, F; Hugenholtz, PG; Laird-Meeter, K; Man in't veld, AJ; Schalekamp, MA; Simoons, ML; Wenting, GJ; Woittiez, AJ, 1983)
"Right ventricular dysfunction was defined as CMR RV ejection fraction < 50%."6.80Usefulness of Speckle-Tracking Imaging for Right Ventricular Assessment after Acute Myocardial Infarction: A Magnetic Resonance Imaging/Echocardiographic Comparison within the Relation between Aldosterone and Cardiac Remodeling after Myocardial Infarction ( Beaumont, M; Girerd, N; Huttin, O; Juillière, Y; Lemarié, J; Lemoine, S; Mandry, D; Marie, PY; Moulin, F; Selton-Suty, C, 2015)
"Non-culprit intermediate coronary atherosclerosis was assessed on intravascular ultrasound."6.77Effects of valsartan, an angiotensin II receptor blocker, on coronary atherosclerosis in patients with acute myocardial infarction who receive an angiotensin-converting enzyme inhibitor. ( Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kusama, I; Morita, S; Nozawa, N; Okuda, J; Ozaki, H; Tsukahara, K; Umemura, S; Yano, H, 2012)
"Smoking and dyslipidemia are more potent risk factors for nonfatal MI in males who have the -344C allele of CYP11B2."6.69Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction. ( Hautanen, A; Kayes, KM; Kupari, M; Manninen, V; Mänttäri, M; Rosenfeld, S; Tenkanen, L; Toivanen, P; White, PC, 1999)
" All patients received three dosing regimens administered in random order: (a) intravenous frusemide: 40 mg bolus then 40 mg h-1 for 3 h, (b) captopril: two 12."6.68The renin angiotensin aldosterone system and frusemide response in congestive heart failure. ( Cerimele, B; Greene, P; Reed, S; Ryan, T; Schwertschlag, U; Voelker, J; Weinberger, M, 1995)
"Aldosterone is an important mediator of the renin-angiotensin-aldosterone system (RAAS) that plays a major role in the pathophysiology of cardiovascular disease as well as regulation of extracellular fluid volume and potassium."6.43Cardiovascular effects of aldosterone and post-acute myocardial infarction pathophysiology. ( Cohn, JN; Colucci, W, 2006)
"Aldosterone blockade has been shown to be effective in reducing total mortality as well as hospitalization for heart failure in patients with systolic left ventricular dysfunction (SLVD) due to chronic heart failure and in patients with SLVD post acute myocardial infarction."6.42Effect of aldosterone blockade in patients with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies. ( Pitt, B, 2004)
"Aldosterone appears to be a main marker of adverse clinical outcome, in accordance with the literature."5.40Prognostic role of aldosterone in patients with acute coronary syndrome: short and medium term follow-up. ( Arnone, G; Arnone, MT; Assennato, P; Corrado, E; Mignano, A; Novo, G; Novo, S; Pitruzzella, V; Rotolo, A, 2014)
"Cardiac rupture is a catastrophic complication that occurs after acute myocardial infarction (MI) and, at present, there are no effective pharmacological strategies for preventing this condition."5.40Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53. ( Bin, J; Cao, S; Chen, B; Fu, Y; Huang, Q; Huang, X; Kitakaze, M; Liao, Y; Lu, D; Xu, D; Zhang, J, 2014)
"Aldosterone levels were assayed in plasma taken from 583 patients within 24-96 h following acute myocardial infarction (MI)."5.35Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction. ( Frampton, CM; Nicholls, MG; Palmer, BR; Pilbrow, AP; Richards, AM; Skelton, L; Yandle, TG, 2008)
"Aldosterone was increased markedly in both the LV and RV at 8 weeks post-MI."5.33Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen. ( Ganten, D; Lal, A; Leenen, FH; Veinot, JP, 2005)
"High aldosterone levels were associated with an almost stepwise increase in rates of in-hospital death (P=0."5.33High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction. ( Barthélémy, O; Benoliel, JJ; Beygui, F; Collet, JP; Dumaine, R; Montalescot, G; Vignolles, N, 2006)
"Aldosterone values were highly correlated with the urine potassium/sodium ratio."5.27The renin-angiotensin--aldosterone system and the clinical course of acute myocardial infarction. ( Ceremuzyński, L; Michorowski, B, 1983)
"This was a double-blind, randomized comparison of isosorbide-5-mononitrate (IS-5-MN), 60 mg given orally, once daily for 11 months to patients (n = 47) with left ventricular (LV) dysfunction following acute myocardial infarction (AMI)."5.12Neurohumoral changes in patients with left ventricular dysfunction following acute myocardial infarction and the effect of nitrate therapy: a randomized, double-blind, placebo-controlled long-term study. ( Ohlin, H; Roijer, A; Thilen, U; Tingberg, E, 2006)
"In RALES, low doses of the mineralocorticoid receptor (MR) antagonist spironolactone, added to standard of care for severe heart failure, improved survival by 30% and lowered hospitalization by 35%."5.11RALES, EPHESUS and redox. ( Funder, JW, 2005)
"Of patients with acute myocardial infarction eligible for the International Study of Infarct Survival-4, randomized to captopril (n = 30) or placebo (n = 33), the captopril group had a significant decrease in blood adrenaline on day 3 compared with baseline values."5.08Effect of early captopril treatment on blood adrenaline levels in acute myocardial infarction (the substudy of ISIS-4). International Study of Infarct Survival-4. ( Budaj, A; Ceremuzyński, L; Herbaczyńska-Cedro, K; Kokot, F, 1998)
"Plasma neurohormones were sequentially analysed in 98 patients with acute myocardial infarction randomized to treatment with enalapril or placebo for 4-6 months."5.07Neurohormonal effects of early treatment with enalapril after acute myocardial infarction and the impact on left ventricular remodelling. ( Held, P; Sigurdsson, A; Swedberg, K; Wall, B, 1993)
"A 12 week randomised, double blind, placebo controlled study on the effect of enalapril (5-20 mg daily) on the concentration of plasma atrial natriuretic peptide level and activity of the sympathetic nervous system and renin angiotensin system was done on 27 patients who had suffered an uncomplicated acute myocardial infarction two to six months earlier."5.07Effect of enalapril on plasma atrial natriuretic peptide in late recovery phase of acute myocardial infarction. ( Hirvonen, T; Mustonen, J; Pyörälä, K; Remes, J; Tenhunen, M; Tikkanen, I, 1991)
" The selective aldosterone blocker, eplerenone (Inspra), is under development for human therapeutic use for treatment of hypertension and heart failure post-myocardial infarction (MI)."4.82Aldosterone target organ protection by eplerenone. ( McMahon, EG; Rocha, R; Rudolph, AE, 2004)
" More recently, the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study has provided firm support for the use of eplerenone (Inspra, Pfizer) in heart failure following acute myocardial infarction in addition to neurohormonal blockade with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and beta-blockers."4.82Eplerenone in the treatment of chronic heart failure. ( Krum, H; Liew, D, 2004)
"Both aldosterone and arginine vasopressin (AVP) are produced in the heart and may participate in cardiac fibrosis."4.12Phosphorylation of CaMK and CREB-Mediated Cardiac Aldosterone Synthesis Induced by Arginine Vasopressin in Rats with Myocardial Infarction. ( Gao, X; Li, J; Lu, G; Peng, L; Zhai, YS, 2022)
"To address this question, we examined data from the dal-OUTCOMES trial that compared the cholesteryl ester transfer protein inhibitor dalcetrapib with placebo, beginning 4 to 12 weeks after an index acute coronary syndrome."3.85Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. ( Ballantyne, CM; Barter, PJ; Gunzburger, E; Kallend, D; Kittelson, J; Leiter, LA; Leitersdorf, E; McMurray, JJ; Nicholls, SJ; Olsson, AG; Pitts, R; Schwartz, GG; Shah, PK; Tardif, JC, 2017)
" We investigated the effects of adding the direct renin inhibitor (DRI), aliskiren, to an ACEI or an ARB on monocyte subsets and myocardial salvage in patients with primary acute myocardial infarction (AMI)."3.78Effect of direct renin inhibitor, aliskiren, on peripheral blood monocyte subsets and myocardial salvage in patients with primary acute myocardial infarction. ( Akasaka, T; Imanishi, T; Ino, Y; Ishibashi, K; Kashiwagi, M; Kitabata, H; Komukai, K; Orii, M; Ozaki, Y; Shimamura, K; Shiono, Y; Sougawa, H; Tanimoto, T; Tsujioka, H, 2012)
"Losartan may reduce reactive fibrosis not only by attenuating the Ald signaling pathway but also by decreasing the expression of MR."3.74[Mechanisms of losartan for inhibition of myocardial fibrosis following myocardial infarction in rats]. ( Bai, SC; Deng, LH; Huang, P; Su, L; Wen, YW; Wu, ZL; Xu, DL, 2008)
"Eplerenone, a selective aldosterone blocker, has been shown to attenuate cardiac fibrosis and decrease cardiovascular events in both experimental and clinical studies."3.73Effects of eplerenone and salt intake on left ventricular remodeling after myocardial infarction in rats. ( Abe, Y; Izumi, T; Mochizuki, S; Taniguchi, I; Urabe, A, 2006)
" The aim of the present study was to evaluate the role of aldosterone and angiotensin II on formation of left ventricular fibrosis induced by chronic beta-adrenergic stimulation with isoproterenol (iso) in the rat heart failure model induced by myocardial infarction (MI)."3.73Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist. ( Bos, R; Findji, L; Lechat, P; Médiani, O; Mougenot, N; Vanhoutte, PM, 2005)
"Oral administration of spironolactone improves cardiac remodeling and its central infusion prevents the increase in sympathetic drive post-myocardial infarction (MI)."3.72Critical role of CNS effects of aldosterone in cardiac remodeling post-myocardial infarction in rats. ( Lal, A; Leenen, FH; Veinot, JP, 2004)
"Adrenomedullin (AM) is expressed in cardiac tissue, and plasma AM levels increase in patients with acute myocardial infarction (MI)."3.72Adrenomedullin administration immediately after myocardial infarction ameliorates progression of heart failure in rats. ( Asada, Y; Cao, Y; Eto, T; Imamura, T; Kangawa, K; Kato, J; Kitamura, K; Marutsuka, K; Nakamura, R; Onitsuka, H, 2004)
"The aim of this study was to assess the effects of the Na+-H+ exchange inhibitor cariporide on left ventricular (LV) morphology and function as well as inflammation in rabbits with heart failure."3.72Inhibition of Na+-H+ exchange by cariporide reduces inflammation and heart failure in rabbits with myocardial infarction. ( Busch, AE; Gerl, M; Licher, T; Ruetten, H; Rungwerth, K; Schäfer, S; Schindler, U, 2004)
"Canrenone attenuates LV interstitial remodeling and reduces filling pressures in rats with postinfarction heart failure."3.71Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. ( Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M, 2002)
" This increase is mediated primarily by cardiac angiotensin II via AT1-subtype receptor and may be involved in post-MI ventricular fibrosis and in control of tissue norepinephrine concentration."3.70Activation of cardiac aldosterone production in rat myocardial infarction: effect of angiotensin II receptor blockade and role in cardiac fibrosis. ( Aupetit-Faisant, B; Carayon, A; Delcayre, C; Heymes, C; Oubénaïssa, A; Robert, V; Silvestre, JS; Swynghedauw, B, 1999)
"The effect of enalapril during healing between 1 day and 6 weeks after myocardial infarction on in vivo changes in ventricular size, shape, mass, and function (asynergy, or akinesis and dyskinesis, and ejection fraction), as determined by serial two-dimensional echocardiography, hemodynamics, postmortem topography (planimetered short- and long-axis ventricular contours), and collagen content (determined by levels of hydroxyproline, a marker for collagen), was measured in 25 instrumented dogs."3.69Effect of enalapril on ventricular remodeling and function during healing after anterior myocardial infarction in the dog. ( Blinston, GE; Jugdutt, BI; Jugdutt, SJ; Khan, MI, 1995)
"Plasma atrial natriuretic factor (ANF), renin activity (PRA), aldosterone and antidiuretic hormone (ADH) were determined in 16 patients with uncomplicated acute myocardial infarction (AMI) for 7 days in all patients and in six patients for 8 more days."3.68Plasma atrial natriuretic factor in patients with acute myocardial infarction. ( Bernardi, P; Capelli, M; Fontana, F; Spagnolo, N, 1990)
"Plasma atrial natriuretic factor, aldosterone, renin activity, and antidiuretic hormone were studied in low output heart failure syndromes: cardiogenic shock in ten patients with acute myocardial infarction of the anterior wall (first group), hypovolemic shock after melena from peptic ulcer in ten subjects (second group), and hypotension with bradycardia syndrome in ten patients with acute myocardial infarction of the inferior wall (third group)."3.68Plasma atrial natriuretic factor in low output heart failure syndromes. ( Bernardi, P; Capelli, M; Fontana, F; Spagnolo, N, 1990)
"Plasma levels of atrial natriuretic peptide (ANP), angiotensin II, aldosterone, and catecholamines were followed for 1 month and then for 4 to 6 months in 55 patients with acute myocardial infarction."3.68Short- and long-term neurohormonal activation following acute myocardial infarction. ( Held, P; Sigurdsson, A; Swedberg, K, 1993)
"Plasma atrial natriuretic factor (ANF) levels were measured in 29 patients who had normal atrial hemodynamics on days 4 and 8 after an uncomplicated acute myocardial infarction (AMI)."3.68Plasma atrial natriuretic factor in uncomplicated acute myocardial infarction. ( Antonopoulos, A; Aspiotis, N; Kyriakidis, M; Marakas, S; Petropoulakis, P; Toutouzas, P; Tselika, C, 1993)
"A serial measurements of plasma renin activity (PRA), serum angiotensin converting enzyme activity (ACE), concentrations of plasma angiotensin II (AII) and plasma aldosterone (Ald) in 38 consecutive patients with acute myocardial infarction (AMI) or suspected AMI showed that PRA, AII and Ald levels increased in patients with AMI, especially within first week after onset, and were significantly higher in those cases with severe complications."3.68[The changes in renin-angiotensin-aldosterone system in acute myocardial infarction and the effects of converting enzyme inhibitor-captopril]. ( Jiang, M, 1991)
"Acute myocardial infarction is associated with complex neuroendocrine changes, including release of arginine vasopressin, norepinephrine, and epinephrine, and activation of the renin-angiotensin system."3.67Neuroendocrine changes in acute myocardial infarction. ( Cobbe, SM; McAlpine, HM, 1988)
"The aim of this paper was to study plasma atrial natriuretic factor, renin activity, aldosterone and antidiuretic hormone in low-output heart failure syndromes such as cardiogenic shock, hypovolemic shock and hypotension with bradycardia syndrome."3.67[Atrial natriuretic factor in cardiogenic shock, in hypovolemic shock and in the bradycardia-hypotension syndrome following acute myocardial infarction]. ( Bernardi, P; Capelli, M; Fontana, F; Spagnolo, N, 1989)
"In patients with mild hypertension, flurbiprofen in a dose of 100 mg daily for 7 days attenuated the hypotensive effect of a single dose of propranolol 80 mg but not of atenolol 100 mg."3.67Flurbiprofen interaction with single doses of atenolol and propranolol. ( Hawksworth, GM; McLean, I; Petrie, JC; Webster, J, 1984)
"The angiotensin-converting enzyme inhibitor, captopril, was given to 19 patients with severe heart failure."3.66Effects of captopril in acute and chronic heart failure. Correlations with plasma levels of noradrenaline, renin, and aldosterone. ( Boomsma, F; Hugenholtz, PG; Laird-Meeter, K; Man in't veld, AJ; Schalekamp, MA; Simoons, ML; Wenting, GJ; Woittiez, AJ, 1983)
"Early detection of adverse effects of novel therapies and understanding of their mechanisms could improve the safety and efficiency of drug development."2.87Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib. ( DeLisle, RK; Ganz, P; Hyde, C; Malarstig, A; Murthy, AC; Ostroff, R; Segal, MR; Weiss, SJ; Williams, SA, 2018)
"Right ventricular dysfunction was defined as CMR RV ejection fraction < 50%."2.80Usefulness of Speckle-Tracking Imaging for Right Ventricular Assessment after Acute Myocardial Infarction: A Magnetic Resonance Imaging/Echocardiographic Comparison within the Relation between Aldosterone and Cardiac Remodeling after Myocardial Infarction ( Beaumont, M; Girerd, N; Huttin, O; Juillière, Y; Lemarié, J; Lemoine, S; Mandry, D; Marie, PY; Moulin, F; Selton-Suty, C, 2015)
"Non-culprit intermediate coronary atherosclerosis was assessed on intravascular ultrasound."2.77Effects of valsartan, an angiotensin II receptor blocker, on coronary atherosclerosis in patients with acute myocardial infarction who receive an angiotensin-converting enzyme inhibitor. ( Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kusama, I; Morita, S; Nozawa, N; Okuda, J; Ozaki, H; Tsukahara, K; Umemura, S; Yano, H, 2012)
"Heart failure is associated with many comorbidities and among them, cancer has stood out as a contributor of death in these patients."2.72RAAS: A Convergent Player in Ischemic Heart Failure and Cancer. ( Cambrón-Mora, D; Garcia-Garduño, TC; Padilla-Gutierrez, JR; Valle, Y, 2021)
"Treatment with captopril affected only plasma renin activity (increase) and aldosterone (decrease)."2.69Two-year time course and significance of neurohumoral activation in the Survival and Ventricular Enlargement (SAVE) Study. ( Bichet, D; Ciampi, A; de Champlain, J; Harel, F; Moyé, LA; Pfeffer, M; Rouleau, JL; Vantrimpont, P, 1998)
"Smoking and dyslipidemia are more potent risk factors for nonfatal MI in males who have the -344C allele of CYP11B2."2.69Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction. ( Hautanen, A; Kayes, KM; Kupari, M; Manninen, V; Mänttäri, M; Rosenfeld, S; Tenkanen, L; Toivanen, P; White, PC, 1999)
" All patients received three dosing regimens administered in random order: (a) intravenous frusemide: 40 mg bolus then 40 mg h-1 for 3 h, (b) captopril: two 12."2.68The renin angiotensin aldosterone system and frusemide response in congestive heart failure. ( Cerimele, B; Greene, P; Reed, S; Ryan, T; Schwertschlag, U; Voelker, J; Weinberger, M, 1995)
"Treatment with prazosin for one month also reduced systemic vascular resistance by 8%, renal vascular resistance increased by 20%, and renal blood flow and the percentage of the cardiac output going to the kidney fell by 14% and 26%."2.66The renal response to neuroendocrine inhibition in chronic heart failure: double-blind comparison of captopril and prazosin. ( Bayliss, J; Canepa-Anson, R; Norell, M; Poole-Wilson, P; Sutton, G, 1986)
"Aldosterone is an important mediator of the renin-angiotensin-aldosterone system (RAAS) that plays a major role in the pathophysiology of cardiovascular disease as well as regulation of extracellular fluid volume and potassium."2.43Cardiovascular effects of aldosterone and post-acute myocardial infarction pathophysiology. ( Cohn, JN; Colucci, W, 2006)
"Aldosterone blockade has been shown to be effective in reducing total mortality as well as hospitalization for heart failure in patients with systolic left ventricular dysfunction (SLVD) due to chronic heart failure and in patients with SLVD post acute myocardial infarction."2.42Effect of aldosterone blockade in patients with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies. ( Pitt, B, 2004)
"Primary aldosteronism is now recognized as the most common cause of secondary hypertension."1.72Primary aldosteronism presenting as embolic myocardial infarction. ( Jin, HY; Kim, YJ; Lee, HW; Lee, KA, 2022)
"A rat model of ventricular remodeling after myocardial infarction was established by left coronary artery ligation."1.42Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats. ( Chen, C; Gao, J; Gao, Y; Guo, J; Wang, H; Wu, R, 2015)
"Cardiac rupture is a catastrophic complication that occurs after acute myocardial infarction (MI) and, at present, there are no effective pharmacological strategies for preventing this condition."1.40Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53. ( Bin, J; Cao, S; Chen, B; Fu, Y; Huang, Q; Huang, X; Kitakaze, M; Liao, Y; Lu, D; Xu, D; Zhang, J, 2014)
"Aldosterone appears to be a main marker of adverse clinical outcome, in accordance with the literature."1.40Prognostic role of aldosterone in patients with acute coronary syndrome: short and medium term follow-up. ( Arnone, G; Arnone, MT; Assennato, P; Corrado, E; Mignano, A; Novo, G; Novo, S; Pitruzzella, V; Rotolo, A, 2014)
" Here we show that aldosterone exerts direct toxic actions on myocardium by oxidative activation of CaMKII, causing cardiac rupture and increased mortality in mice after myocardial infarction."1.37Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. ( Allamargot, C; Anderson, ME; Blankesteijn, WM; Grumbach, IM; Guan, X; He, BJ; Heymans, S; Joiner, ML; Koval, OM; Kutschke, W; Luczak, ED; Mohler, PJ; Sigmund, CD; Singh, MV; Spitz, DR; Swaminathan, PD; Weiss, RM; Yang, J; Zimmerman, K, 2011)
"Aldosterone levels were assayed in plasma taken from 583 patients within 24-96 h following acute myocardial infarction (MI)."1.35Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction. ( Frampton, CM; Nicholls, MG; Palmer, BR; Pilbrow, AP; Richards, AM; Skelton, L; Yandle, TG, 2008)
"High aldosterone levels were associated with an almost stepwise increase in rates of in-hospital death (P=0."1.33High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction. ( Barthélémy, O; Benoliel, JJ; Beygui, F; Collet, JP; Dumaine, R; Montalescot, G; Vignolles, N, 2006)
"Aldosterone was increased markedly in both the LV and RV at 8 weeks post-MI."1.33Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen. ( Ganten, D; Lal, A; Leenen, FH; Veinot, JP, 2005)
"The study was made in 45 patients with congestive heart failure treated in the Department of Cardiology."1.32[Cytokines and remodeling of the heart in patients with congestive heart failure]. ( Jołda-Mydłowska, B; Salomon, P, 2003)
"Collagen scar formation was evaluated by measurement of serum concentrations of the aminoterminal propeptide of type III procollagen (PIIINP), the aminoterminal propeptide of type I procollagen (intact PINP), and the carboxyterminal propeptide of type I procollagen (PICP)."1.30Collagen scar formation after acute myocardial infarction: relationships to infarct size, left ventricular function, and coronary artery patency. ( Ikäheimo, M; Jounela, A; Lumme, J; Niemelä, M; Peuhkurinen, K; Risteli, J; Uusimaa, P, 1997)
"Aldosterone values were highly correlated with the urine potassium/sodium ratio."1.27The renin-angiotensin--aldosterone system and the clinical course of acute myocardial infarction. ( Ceremuzyński, L; Michorowski, B, 1983)

Research

Studies (192)

TimeframeStudies, this research(%)All Research%
pre-199045 (23.44)18.7374
1990's42 (21.88)18.2507
2000's56 (29.17)29.6817
2010's35 (18.23)24.3611
2020's14 (7.29)2.80

Authors

AuthorsStudies
Parksook, WW1
Williams, GH1
Lee, HW1
Kim, YJ1
Jin, HY1
Lee, KA1
Salama, ABM1
Abouleisa, RRE1
Ou, Q1
Tang, XL1
Alhariry, N1
Hassan, S1
Gebreil, A1
Dastagir, M1
Abdulwali, F1
Bolli, R1
Mohamed, TMA1
Zhai, YS2
Li, J3
Peng, L2
Lu, G2
Gao, X2
Lee, SH1
Rhee, TM1
Shin, D1
Hong, D1
Choi, KH1
Kim, HK1
Park, TK1
Yang, JH1
Song, YB1
Hahn, JY1
Choi, SH1
Chae, SC1
Cho, MC1
Kim, CJ1
Kim, JH1
Kim, HS1
Gwon, HC1
Jeong, MH1
Lee, JM1
Monzo, L1
Huttin, O2
Ferreira, JP1
Lamiral, Z1
Bozec, E1
Beaumont, M2
Micard, E1
Baudry, G1
Marie, PY2
Eschalier, R1
Rossignol, P1
Zannad, F3
Girerd, N2
Klapper-Goldstein, H2
Murninkas, M2
Gillis, R2
Mulla, W1
Levanon, E1
Elyagon, S2
Schuster, R1
Danan, D1
Cohen, H1
Etzion, Y2
Azizi, M1
Dragasevic, N1
Jakovljevic, V1
Zivkovic, V1
Draginic, N1
Andjic, M1
Bolevich, S1
Jovic, S1
Verma, A1
Pittala, S1
Paul, A1
Shoshan-Barmatz, V1
Zhang, X1
Shao, C1
Cheng, S2
Zhu, Y1
Liang, B1
Gu, N1
Guitart-Mampel, M1
Urquiza, P1
Borges, JI1
Lymperopoulos, A4
Solesio, ME1
Garcia-Garduño, TC1
Padilla-Gutierrez, JR1
Cambrón-Mora, D1
Valle, Y1
Mandal, R1
Kaur, S1
Gupta, VK1
Joshi, A1
Joseph, JJ1
Echouffo-Tcheugui, JB1
Kalyani, RR1
Yeh, HC1
Bertoni, AG1
Effoe, VS1
Casanova, R1
Sims, M1
Wu, WC1
Wand, GS1
Correa, A1
Golden, SH1
Williams, SA1
Murthy, AC1
DeLisle, RK1
Hyde, C1
Malarstig, A1
Ostroff, R1
Weiss, SJ1
Segal, MR1
Ganz, P1
Hillaert, MA2
den Ruijter, HM1
Hoefer, IE1
Lentjes, EG1
de Borst, GJ1
de Vries, JPM1
Doevendans, PA2
Pasterkamp, G1
Timmers, L1
Docherty, KF1
Jhund, PS1
Cannone, V1
Buglioni, A1
Sangaralingham, SJ1
Scott, C1
Bailey, KR1
Rodeheffer, R1
Redfield, MM1
Sarzani, R1
Burnett, JC1
Resic, N1
Durak-Nalbantic, A1
Dzubur, A1
Begic, A1
Begic, E1
Mignano, A1
Pitruzzella, V1
Arnone, G1
Arnone, MT1
Rotolo, A1
Assennato, P1
Novo, G1
Corrado, E1
Novo, S1
Bathgate-Siryk, A2
Dabul, S2
Pandya, K1
Walklett, K2
Rengo, G3
Cannavo, A1
De Lucia, C1
Liccardo, D1
Gao, E1
Leosco, D1
Koch, WJ3
Ozaki, Y2
Imanishi, T2
Tanimoto, T2
Teraguchi, I1
Nishiguchi, T1
Orii, M2
Shiono, Y2
Shimamura, K2
Yamano, T1
Ino, Y2
Yamaguchi, T1
Kubo, T1
Akasaka, T2
Chen, B1
Lu, D1
Fu, Y1
Zhang, J1
Huang, X1
Cao, S1
Xu, D1
Bin, J1
Kitakaze, M1
Huang, Q1
Liao, Y1
Hu, J1
Li, Y1
Cheng, W1
Yang, Z1
Wang, F1
Lv, P1
Niu, C1
Hou, Y1
Yan, Y1
Ge, J1
Rafatian, N1
Westcott, KV2
White, RA3
Leenen, FH6
Sturchler, E1
Garcia, D1
McDonald, P1
Lemarié, J1
Mandry, D1
Juillière, Y1
Moulin, F1
Lemoine, S1
Selton-Suty, C1
Gao, Y1
Gao, J1
Chen, C1
Wang, H1
Guo, J1
Wu, R1
Alexandre, J1
Hof, T1
Puddu, PE1
Rouet, R1
Guinamard, R1
Manrique, A1
Beygui, F5
Sallé, L1
Milliez, P1
Xanthakis, V1
Enserro, DM1
Larson, MG1
Wollert, KC1
Januzzi, JL1
Levy, D1
Aragam, J1
Benjamin, EJ1
Wang, TJ1
Mitchell, GF1
Vasan, RS1
Pitts, R1
Gunzburger, E1
Ballantyne, CM1
Barter, PJ1
Kallend, D1
Leiter, LA1
Leitersdorf, E1
Nicholls, SJ1
Shah, PK1
Tardif, JC2
Olsson, AG1
McMurray, JJ2
Kittelson, J1
Schwartz, GG1
Huang, BS3
Ahmad, M2
Tan, J1
Jeng, AY1
Palmer, BR2
Pilbrow, AP2
Frampton, CM2
Yandle, TG2
Skelton, L2
Nicholls, MG2
Richards, AM3
Pitt, B4
Wu, ZL1
Xu, DL1
Deng, LH1
Wen, YW1
Huang, P1
Bai, SC1
Su, L1
Montalescot, G4
Vicaut, E2
Rouanet, S1
Van Belle, E3
Baulac, C1
Degrandsart, A1
Dallongeville, J2
Mihailidou, AS1
Loan Le, TY1
Mardini, M1
Funder, JW2
Martinez, FA1
Ecollan, P1
Machecourt, J1
Zincarelli, C1
Kim, J1
Vergaro, G1
Emdin, M1
Iervasi, A1
Zyw, L1
Gabutti, A1
Poletti, R1
Mammini, C1
Giannoni, A1
Fontana, M1
Passino, C1
Boccanelli, A1
Agostoni, P1
Ivanes, F1
Susen, S1
Mouquet, F1
Pigny, P1
Cuilleret, F1
Sautière, K1
Collet, JP2
Hennache, B1
Ennezat, PV1
Juthier, F1
Richard, F1
Jude, B1
Bertrand, M1
Mill, JG1
Stefanon, I1
dos Santos, L1
Baldo, MP1
Weir, RA1
Tsorlalis, IK1
Steedman, T1
Dargie, HJ1
Fraser, R1
Connell, JM1
He, BJ1
Joiner, ML1
Singh, MV1
Luczak, ED1
Swaminathan, PD1
Koval, OM1
Kutschke, W1
Allamargot, C1
Yang, J1
Guan, X1
Zimmerman, K1
Grumbach, IM1
Weiss, RM1
Spitz, DR1
Sigmund, CD1
Blankesteijn, WM1
Heymans, S1
Mohler, PJ1
Anderson, ME1
Ohtani, K1
Usui, S1
Kaneko, S1
Takashima, S1
Kitano, K1
Yamamoto, K1
Okajima, M1
Furusho, H1
Takamura, M1
Chabot, A1
Jiang, BH1
Shi, Y1
Dupuis, J1
Kashiwagi, M1
Tsujioka, H1
Sougawa, H1
Ishibashi, K1
Komukai, K1
Kitabata, H1
Butler, J1
Ezekowitz, JA1
Collins, SP1
Givertz, MM1
Teerlink, JR1
Walsh, MN1
Albert, NM1
Westlake Canary, CA1
Carson, PE1
Colvin-Adams, M1
Fang, JC1
Hernandez, AF1
Hershberger, RE1
Katz, SD1
Rogers, JG1
Spertus, JA1
Stevenson, WG1
Sweitzer, NK1
Tang, WH1
Stough, WG1
Starling, RC1
Yano, H1
Hibi, K1
Nozawa, N1
Ozaki, H1
Kusama, I1
Ebina, T1
Kosuge, M1
Tsukahara, K1
Okuda, J1
Morita, S1
Umemura, S1
Kimura, K1
Galuppo, P2
Bauersachs, J2
Noda, K1
Kobara, M1
Hamada, J1
Yoshifuji, Y1
Shiraishi, T1
Tanaka, T1
Wang, J1
Toba, H1
Nakata, T1
Marc, Y1
Llorens-Cortes, C1
Sanderson, JE1
Cittadini, A1
Casaburi, C1
Monti, MG1
Di Gianni, A1
Serpico, R1
Scherillo, G1
Saldamarco, L1
Vanasia, M1
Saccà, L1
Jessup, M1
Casal, AJ1
Silvestre, JS4
Delcayre, C4
Capponi, AM1
Sheppard, KE1
Jołda-Mydłowska, B1
Salomon, P1
GARAGNANI, A2
SURIANI, L3
BRILLANTE, C3
RAPINO, P1
RAVENNI, G1
RUBEGNI, M1
DI PERRI, T1
CHIERICI, F1
MANZINI, E1
WEXLER, BC3
KITTINGER, GW1
Yakobson, GS1
Antonov, AR2
Efremov, AV2
Makhanova, NA1
Shmerling, MD1
Maksimov, VF1
Korostyshevskaya, IM1
Yakobson, MG1
Christ, M1
Grimm, W1
Maisch, B2
Rebsamen, MC1
Perrier, E1
Gerber-Wicht, C1
Benitah, JP1
Lang, U1
Rudolph, AE1
Rocha, R1
McMahon, EG2
Lacour, C1
Roccon, A1
Galindo, G1
Canals, F1
Hogie, M1
Segondy, D1
Briand, D1
Roque, C1
Herbert, JM1
Nisato, D1
Krum, H1
Liew, D1
Rungwerth, K1
Schindler, U1
Gerl, M1
Schäfer, S1
Licher, T1
Busch, AE1
Ruetten, H1
Nakamura, R1
Kato, J1
Kitamura, K1
Onitsuka, H1
Imamura, T1
Cao, Y1
Marutsuka, K1
Asada, Y1
Kangawa, K1
Eto, T1
Tan, LB1
Schlosshan, D1
Barker, D1
Saito, Y1
Lal, A2
Veinot, JP2
Bos, R1
Mougenot, N1
Findji, L1
Médiani, O1
Vanhoutte, PM1
Lechat, P1
Heinzl, S1
Struthers, AD1
Katada, J1
Meguro, T1
Saito, H1
Ohashi, A1
Anzai, T1
Ogawa, S1
Yoshikawa, T1
Ganten, D1
Westendorp, B2
Schoemaker, RG2
Buikema, H2
Boomsma, F2
van Veldhuisen, DJ1
van Gilst, WH2
Sun, Y4
Weber, KT5
Kessler-Icekson, G1
Schlesinger, H1
Freimann, S1
Kessler, E1
Chai, W1
Garrelds, IM1
de Vries, R1
Danser, AH1
Kalantarinia, K1
Okusa, MD1
Cohn, JN1
Colucci, W1
Collins, RP1
Troughton, RW1
Cameron, VA2
Tingberg, E1
Roijer, A1
Thilen, U1
Ohlin, H1
Benoliel, JJ1
Vignolles, N1
Dumaine, R1
Barthélémy, O1
Urabe, A1
Izumi, T1
Abe, Y1
Taniguchi, I1
Mochizuki, S1
Calhoun, DA1
Brandes, RP1
Fraccarollo, D1
Schraut, S1
Kneitz, S1
van Rooijen, N1
Ertl, G1
Wenting, GJ1
Man in't veld, AJ1
Woittiez, AJ1
Laird-Meeter, K1
Simoons, ML1
Hugenholtz, PG1
Schalekamp, MA1
Michorowski, B1
Ceremuzyński, L3
Prys-Roberts, C1
Webster, J1
Petrie, JC1
McLean, I1
Hawksworth, GM1
Iakobson, MG3
Kuimov, AD3
Sorokin, AS2
Gizatulin, ZIa1
Golikov, AP3
Ivleva, VI2
Malaev, MG2
Laragh, JH2
Raman, VK1
Lee, YA1
Lindpaintner, K1
Reed, S1
Greene, P1
Ryan, T1
Cerimele, B1
Schwertschlag, U1
Weinberger, M1
Voelker, J1
Brilla, CG1
Rupp, H1
Funck, R1
Zhou, G1
Jugdutt, BI1
Khan, MI1
Jugdutt, SJ1
Blinston, GE1
Rouleau, JL3
Packer, M2
Moyé, L2
de Champlain, J3
Bichet, D3
Klein, M2
Rouleau, JR1
Sussex, B2
Arnold, JM2
Sestier, F2
Dagenais, GR1
Bellone, P2
Derchi, G2
Tommasini, G2
Biorci, ML2
Randazzo, M2
Primarolo, P2
Vecchio, C2
Pouleur, H1
Sigurdsson, A2
Held, P2
Swedberg, K2
Kyriakidis, M1
Petropoulakis, P1
Aspiotis, N1
Tselika, C1
Antonopoulos, A1
Marakas, S1
Toutouzas, P1
Wall, B1
Borghi, C1
Boschi, S1
Ambrosioni, E1
Melandri, G1
Branzi, A1
Magnani, B1
González-Fernández, RA1
Altieri, PI1
Lugo, JE1
Fernández-Martínez, J1
Fujiwara, M1
Asakuma, S1
Nakamura, T1
Nakamura, K1
Iwasaki, T1
Cleutjens, JP1
Tanabe, K1
Suzuki, N1
Osada, N1
Yamamoto, A1
Nakayama, M1
Yokoyama, Y1
Sakakibara, M1
Itoh, H1
Murayama, M1
Yamada, S1
Yamasaki, H1
Uusimaa, P1
Risteli, J1
Niemelä, M1
Lumme, J1
Ikäheimo, M1
Jounela, A1
Peuhkurinen, K1
Budaj, A1
Herbaczyńska-Cedro, K1
Kokot, F1
Vantrimpont, P1
Ciampi, A1
Harel, F1
Moyé, LA1
Pfeffer, M1
Harrington, JL1
Farley, DR1
van Heerden, JA1
Ramin, KD1
Heymes, C2
Oubénaïssa, A3
Robert, V3
Aupetit-Faisant, B2
Carayon, A2
Swynghedauw, B3
Hautanen, A1
Toivanen, P1
Mänttäri, M1
Tenkanen, L1
Kupari, M1
Manninen, V1
Kayes, KM1
Rosenfeld, S1
White, PC1
Rademaker, MT1
Charles, CJ1
Espiner, EA1
Pemberton, CJ1
Markel', AL1
Petrova, GV1
Iakobson, GS2
Garnier, A1
Cailmail, S1
Tatara, E1
Pasquale, PD1
Stefano, GD1
Paterna, S1
Williams, G1
Remme, W1
Martinez, F1
Lopez-Sendon, J1
Neaton, J1
Roniker, B1
Hurley, S1
Burns, D1
Bittman, R1
Kleiman, J1
Kikuchi, M1
Nakamura, M2
Suzuki, T1
Sato, M1
Takino, T1
Hiramori, K1
Hayashi, M1
Tsutamoto, T1
Wada, A1
Maeda, K1
Mabuchi, N1
Tsutsui, T1
Matsui, T1
Fujii, M1
Matsumoto, T1
Yamamoto, T1
Horie, H1
Ohnishi, M1
Kinoshita, M1
Remme, WJ1
Xiu, JC1
Wu, P1
Xu, JP1
Guo, Z1
Lai, W1
Zhang, Y1
Li, S1
Liu, Y1
Abenhaim, L1
Kuchel, O1
Drozdova, ES2
Salem, S1
Rossel's, AN1
Orlov, AI1
Bogdanovich, NK1
Bobkov, AI1
Zysko, AP1
Belianin, VI1
Stepanova, IP1
Mrochek, AG1
Sytyĭ, VP1
Livshits, IB1
Sherstiuk, GV1
Alekseeva, DD1
Ivanchikov, VI1
Kripskaia, NE1
Jiang, M1
Volpe, M1
Lembo, G1
De Luca, N1
Lamenza, F1
Tritto, C1
Ricciardelli, B1
Molaro, M1
De Campora, P1
Condorelli, G1
Rendina, V1
Gutierrez-Marcos, FM1
Fernandez-Cruz, A1
Gutkowska, J1
Herrero, C1
Blesa, A1
Estrada, V1
Loscos, C1
López-Novoa, JM1
Prachar, H1
Hirvonen, T1
Remes, J1
Mustonen, J1
Tikkanen, I1
Tenhunen, M1
Pyörälä, K1
De Marzio, P1
Morelli, S1
Ferri, C1
Cacciafesta, M1
Bellini, C1
Perrone, A1
Aguglia, F1
Santucci, A1
Balsano, F1
Kageyama, Y1
Suzuki, H1
Saruta, T1
Markuljak, I1
Kvĕtenský, J1
Funiak, S1
Záhradný, V1
Vladár, L1
Vaughan, DE1
Lamas, GA1
Pfeffer, MA1
Fontana, F3
Bernardi, P5
Spagnolo, N3
Capelli, M3
Arakawa, N1
Kato, M1
Zhao, L1
Meissner, D1
Hubl, W1
Schmidt, PK1
Zabello, IN1
Hodsman, GP1
Kohzuki, M1
Howes, LG1
Sumithran, E1
Tsunoda, K1
Johnston, CI1
McAlpine, HM1
Cobbe, SM1
Bayliss, J1
Canepa-Anson, R1
Norell, M1
Poole-Wilson, P1
Sutton, G1
Leor, R1
Stalnikowicz, R1
Koshu, M1
Sugimoto, T1
Terada, Y1
Uraoka, T1
Malaia, IT1
Lazareva, SA1
Brunner, HR1
Baer, L1
Newton, MA1
Goodwin, FT1
Krakoff, LR1
Bard, RH1
Bühler, FR1
Wood, JE1
Arora, RB4
Judd, JT2
Lutmer, RJ1
Saroff, J2
Omel'chenko, AP1
Goncharova, DN1
Weil, MH1
Shubin, H1
Gupta, SK1
Sharma, RC1
Siddiqui, HH2
Lutmer, RF1
Korochkin, IM1
Matveeva, IV1
Korolova, SA1
Lenzi, S1
Descovich, GC2
Siemon, G1
Chazov, EI1
Gritti, FM1
Montini, T1
Perrini, M1
Piliego, N1
Rossini, P1
Del Zotti, G1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Mineralcorticoid Recept Antagonist on Cardiovascular Disease in Patients With Hypertension and Hyperaldosteronemia:A Multicenter Randomized Controlled Study[NCT05688579]Phase 48,000 participants (Anticipated)Interventional2023-04-16Enrolling by invitation
Evaluating the Impact of SomaSignal Tests on Medical Management and Change in Risk in Patients at Higher Risk of Cardiovascular Disease: A Feasibility and an Adaptive Implementation Study (SomaSignal Study)[NCT04836117]200 participants (Anticipated)Interventional2021-08-12Recruiting
Phase 3 Multi Center, Double Blind, Randomized, Parallel Group Evaluation Of The Fixed Combination Torcetrapib/Atorvastatin, Administered Orally, Once Daily (Qd), Compared With Atorvastatin Alone, On The Occurrence Of Major Cardiovascular Events In Subjec[NCT00134264]Phase 315,067 participants (Actual)Interventional2004-07-31Terminated
A Safety and Feasibility Study of Water-only Fasting and Refeeding for Treatment of Stage 1 and 2 Hypertensive Patients[NCT04515095]30 participants (Actual)Interventional2020-08-16Completed
Multiparametric Study of Cardiac Remodeling After Myocardial Infarction Revascularized in Acute Phase : Relation With the Serum Concentrations in Aldosterone[NCT01109225]145 participants (Actual)Interventional2010-04-27Completed
A Randomized, Double-blind, Placebo-controlled Study Assessing the Effect of RO4607381 on Cardiovascular Mortality and Morbidity in Clinically Stable Patients With a Recent Acute Coronary Syndrome[NCT00658515]Phase 315,871 participants (Actual)Interventional2008-04-30Completed
Aldosterone Lethal Effects Blocked in AMI Treated With or Without Reperfusion to Improve Outcome and Survival at Six Months Follow-up: THE ALBATROSS TRIAL[NCT01059136]Phase 31,603 participants (Actual)Interventional2010-02-28Completed
The Effects of Eplerenone on Left Ventricular Remodelling Post-Acute Myocardial Infarction: a Double-Blind Placebo-Controlled Cardiac MR-Based Study[NCT00132093]Phase 4100 participants Interventional2005-04-30Completed
Cardiac Allograft Remodeling and Effects of Sirolimus on Its Progression[NCT01889992]Phase 142 participants (Actual)Interventional2013-04-24Terminated (stopped due to PI left University and project not continued)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline for HDL Cholesterol

(NCT00658515)
Timeframe: At 53 Months

Interventionmg/dL (Least Squares Mean)
Dalcetrapib (RO4607381)44.96
Placebo15.60

Composite Endpoint:All Cause Mortality

(NCT00658515)
Timeframe: Throughout Study, up to 53 Months

InterventionParticipants (Count of Participants)
Dalcetrapib (RO4607381)226
Placebo229

Incidence of Cardiovascular Mortality and Morbidity

Number of cardiovascular events per patient per year (NCT00658515)
Timeframe: From date of randomization to first event up to 48 months

InterventionEvent per Patient Years of Followup (Number)
Dalcetrapib (RO4607381)0.034050
Placebo0.032759

Reviews

34 reviews available for aldosterone and Myocardial Infarction

ArticleYear
Aldosterone and cardiovascular diseases.
    Cardiovascular research, 2023, 03-17, Volume: 119, Issue:1

    Topics: Aldosterone; Atherosclerosis; Atrial Fibrillation; Cardiovascular Diseases; Heart Failure; Humans; H

2023
Aldosterone receptor antagonists.
    Annales d'endocrinologie, 2021, Volume: 82, Issue:3-4

    Topics: Aldosterone; Blood Pressure; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Antagon

2021
The role of aldosterone inhibitors in cardiac ischemia-reperfusion injury.
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:1

    Topics: Aldosterone; Animals; Cardiotonic Agents; Clinical Trials as Topic; Disease Models, Animal; Heart Ve

2021
Impact of Aldosterone on the Failing Myocardium: Insights from Mitochondria and Adrenergic Receptors Signaling and Function.
    Cells, 2021, 06-19, Volume: 10, Issue:6

    Topics: Aldosterone; Animals; Heart Failure; Humans; Mitochondria, Heart; Myocardial Infarction; Myocardium;

2021
RAAS: A Convergent Player in Ischemic Heart Failure and Cancer.
    International journal of molecular sciences, 2021, Jul-01, Volume: 22, Issue:13

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Myocar

2021
Brain renin-angiotensin-aldosterone system and ventricular remodeling after myocardial infarct: a review.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:12

    Topics: Aldosterone; Animals; Apoptosis; Brain; Humans; Myocardial Infarction; Myocarditis; Myocytes, Cardia

2009
Remodeling in the ischemic heart: the stepwise progression for heart failure.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2011, Volume: 44, Issue:9

    Topics: Adrenergic Neurons; Aldosterone; Angiotensins; Apoptosis; Arrhythmias, Cardiac; Heart; Heart Failure

2011
Mineralocorticoid receptor activation in myocardial infarction and failure: recent advances.
    European journal of clinical investigation, 2012, Volume: 42, Issue:10

    Topics: Aldosterone; Genetic Techniques; Heart Failure; Humans; Hyperkalemia; Mineralocorticoid Receptor Ant

2012
Corticosteroid receptors, 11 beta-hydroxysteroid dehydrogenase, and the heart.
    Vitamins and hormones, 2003, Volume: 66

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aldosterone; Animals; Binding Sites;

2003
Aldosterone blockade in patients with systolic left ventricular dysfunction.
    Circulation, 2003, Oct-14, Volume: 108, Issue:15

    Topics: Aldosterone; Eplerenone; Forecasting; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Mal

2003
[Significance of aldosterone antagonist therapy].
    Der Internist, 2004, Volume: 45, Issue:3

    Topics: Aldosterone; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dr

2004
Effect of aldosterone blockade in patients with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Digoxin; Enzyme Inhibitors; Eplerenone; Female; Human

2004
Aldosterone target organ protection by eplerenone.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Aldosterone; Blood Vessels; Brain; Clinical Trials as Topic; Eplerenone; Heart Failure; Humans; Hype

2004
Eplerenone in the treatment of chronic heart failure.
    Expert review of cardiovascular therapy, 2004, Volume: 2, Issue:3

    Topics: Aldosterone; Chronic Disease; Clinical Trials as Topic; Eplerenone; Heart Failure; Humans; Mineraloc

2004
Fiftieth anniversary of aldosterone: from discovery to cardiovascular therapy.
    International journal of cardiology, 2004, Volume: 96, Issue:3

    Topics: Aldosterone; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; R

2004
[Therapeutic application of ANP: past and future].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Cardiopulmonary Bypass; Chronic Disease; Cyclic GMP

2004
Pathophysiology of heart failure following myocardial infarction.
    Heart (British Cardiac Society), 2005, Volume: 91 Suppl 2

    Topics: Aldosterone; Angiotensins; Fibrosis; Heart Failure; Humans; Hypertrophy, Left Ventricular; Myocardia

2005
The renin-angiotensin system and its blockade in diabetic renal and cardiovascular disease.
    Current diabetes reports, 2006, Volume: 6, Issue:1

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiovascu

2006
Cardiovascular effects of aldosterone and post-acute myocardial infarction pathophysiology.
    The American journal of cardiology, 2006, May-22, Volume: 97, Issue:10A

    Topics: Aldosterone; Animals; Humans; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Ventric

2006
Pathophysiology of hypertension and ischemic heart disease.
    International anesthesiology clinics, 1980,Winter, Volume: 18, Issue:4

    Topics: Adult; Aldosterone; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Endocardium; Hear

1980
Hormonal and metabolic reactions evoked by acute myocardial infarction.
    Circulation research, 1981, Volume: 48, Issue:6 Pt 1

    Topics: Acute Disease; Adrenergic Fibers; Aldosterone; Angina Pectoris, Variant; Animals; Catecholamines; Ca

1981
Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke).
    Journal of human hypertension, 1995, Volume: 9, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disorders; Electrolyt

1995
The cardiac renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy.
    The American journal of cardiology, 1995, Nov-02, Volume: 76, Issue:13

    Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; An

1995
Pharmacological modulation of cardiac fibroblast function.
    Herz, 1995, Volume: 20, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomyopathy, Dilated; Collagen; E

1995
Role of neurohormones in ventricular adaptation and failure.
    The American journal of cardiology, 1994, Apr-07, Volume: 73, Issue:10

    Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Cardiomegaly; Disease Models, Anima

1994
Tissue angiotensin II and myocardial infarction.
    EXS, 1996, Volume: 76

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Col

1996
Structural remodeling of the infarcted rat heart.
    EXS, 1996, Volume: 76

    Topics: Aldosterone; Angiotensin II; Animals; Collagen; Fibrosis; Humans; Metalloendopeptidases; Myocardial

1996
Cardiac remodelling by fibrous tissue: role of local factors and circulating hormones.
    Annals of medicine, 1998, Volume: 30 Suppl 1

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Endomyocardial Fibro

1998
Cardiac aldosterone production and ventricular remodeling.
    Kidney international, 2000, Volume: 57, Issue:4

    Topics: Aldosterone; Animals; Fibrosis; Humans; Myocardial Infarction; Myocardium; Ventricular Remodeling

2000
Mineralocorticoids and cardiovascular diseases. Status of knowledge from experimental and clinical studies.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:9

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Blood Vessels; Cardiovasc

2000
Recent studies with eplerenone, a novel selective aldosterone receptor antagonist.
    Current opinion in pharmacology, 2001, Volume: 1, Issue:2

    Topics: Aldosterone; Animals; Cardiovascular System; Clinical Trials as Topic; Endothelium, Vascular; Eplere

2001
[Prostaglandins, kallikrein-kinin and dopamine. Practical implications of this vasodilator-natriuretic system].
    L'union medicale du Canada, 1979, Volume: 108, Issue:6

    Topics: Aldosterone; Angiotensin II; Anti-Inflammatory Agents; Arachidonic Acids; Bartter Syndrome; Bradykin

1979
The cardiovascular effects of oral contraceptives.
    Modern concepts of cardiovascular disease, 1972, Volume: 41, Issue:8

    Topics: Aldosterone; Angiotensin II; Blood Coagulation; Blood Flow Velocity; Blood Vessels; Cardiovascular S

1972
Shock following acute myocardial infarction. Current understanding of hemodynamic mechanisms.
    Progress in cardiovascular diseases, 1968, Volume: 11, Issue:1

    Topics: Acidosis; Aldosterone; Animals; Arrhythmias, Cardiac; Arteries; Blood Flow Velocity; Blood Pressure;

1968

Trials

21 trials available for aldosterone and Myocardial Infarction

ArticleYear
Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.
    Circulation, 2018, 03-06, Volume: 137, Issue:10

    Topics: Aged; Aldosterone; Anticholesteremic Agents; Biomarkers, Pharmacological; Case-Control Studies; Chol

2018
Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.
    Circulation, 2018, 03-06, Volume: 137, Issue:10

    Topics: Aged; Aldosterone; Anticholesteremic Agents; Biomarkers, Pharmacological; Case-Control Studies; Chol

2018
Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.
    Circulation, 2018, 03-06, Volume: 137, Issue:10

    Topics: Aged; Aldosterone; Anticholesteremic Agents; Biomarkers, Pharmacological; Case-Control Studies; Chol

2018
Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.
    Circulation, 2018, 03-06, Volume: 137, Issue:10

    Topics: Aged; Aldosterone; Anticholesteremic Agents; Biomarkers, Pharmacological; Case-Control Studies; Chol

2018
Effect of direct renin inhibitor on left ventricular remodeling in patients with primary acute myocardial infarction.
    International heart journal, 2014, Volume: 55, Issue:1

    Topics: Aged; Aldosterone; Amides; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme In

2014
Usefulness of Speckle-Tracking Imaging for Right Ventricular Assessment after Acute Myocardial Infarction: A Magnetic Resonance Imaging/Echocardiographic Comparison within the Relation between Aldosterone and Cardiac Remodeling after Myocardial Infarction
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2015, Volume: 28, Issue:7

    Topics: Aldosterone; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Humans; Magnetic Reso

2015
Rationale for an early aldosterone blockade in acute myocardial infarction and design of the ALBATROSS trial.
    American heart journal, 2010, Volume: 160, Issue:4

    Topics: Aged; Aldosterone; Canrenoic Acid; Dose-Response Relationship, Drug; Electrocardiography; Female; Fo

2010
Aldosterone and cortisol predict medium-term left ventricular remodelling following myocardial infarction.
    European journal of heart failure, 2011, Volume: 13, Issue:12

    Topics: Aldosterone; Biomarkers; Double-Blind Method; Echocardiography; Electrocardiography; Eplerenone; Fem

2011
Effects of valsartan, an angiotensin II receptor blocker, on coronary atherosclerosis in patients with acute myocardial infarction who receive an angiotensin-converting enzyme inhibitor.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:6

    Topics: Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors

2012
RALES, EPHESUS and redox.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 93, Issue:2-5

    Topics: Aldosterone; Animals; Heart Failure; Humans; Inflammation; Mineralocorticoid Receptor Antagonists; M

2005
Neurohumoral changes in patients with left ventricular dysfunction following acute myocardial infarction and the effect of nitrate therapy: a randomized, double-blind, placebo-controlled long-term study.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:4

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Double-Blind Method; Echocardiography; Female;

2006
The renin angiotensin aldosterone system and frusemide response in congestive heart failure.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:1

    Topics: Administration, Oral; Aged; Aldosterone; Captopril; Cross-Over Studies; Drug Therapy, Combination; F

1995
Prognostic value of neurohumoral activation in patients with an acute myocardial infarction: effect of captopril.
    Journal of the American College of Cardiology, 1994, Volume: 24, Issue:3

    Topics: Aged; Aldosterone; Analysis of Variance; Arginine Vasopressin; Atrial Natriuretic Factor; Canada; Ca

1994
Activation of neurohumoral systems in postinfarction left ventricular dysfunction.
    Journal of the American College of Cardiology, 1993, Volume: 22, Issue:2

    Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Cardiac Output, Low; Dopamine; Female; Humans; Male; M

1993
Neurohormonal effects of early treatment with enalapril after acute myocardial infarction and the impact on left ventricular remodelling.
    European heart journal, 1993, Volume: 14, Issue:8

    Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Dopamine; Double-Blind Method; Enalapril; Ep

1993
Evidence of a partial escape of renin-angiotensin-aldosterone blockade in patients with acute myocardial infarction treated with ACE inhibitors.
    Journal of clinical pharmacology, 1993, Volume: 33, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dose-Response Rela

1993
Effects of enalapril on ventricular volumes and neurohumoral status after inferior wall myocardial infarction.
    The American journal of the medical sciences, 1993, Volume: 305, Issue:4

    Topics: Aged; Aldosterone; Angiotensin II; Cardiac Volume; Double-Blind Method; Enalapril; Female; Humans; M

1993
Effects of cilazapril on exercise tolerance in the chronic phase of acute myocardial infarction.
    Japanese circulation journal, 1996, Volume: 60, Issue:11

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Ca

1996
Effect of early captopril treatment on blood adrenaline levels in acute myocardial infarction (the substudy of ISIS-4). International Study of Infarct Survival-4.
    The American journal of cardiology, 1998, Feb-01, Volume: 81, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Epinephrine; Female; Humans; Male;

1998
Two-year time course and significance of neurohumoral activation in the Survival and Ventricular Enlargement (SAVE) Study.
    European heart journal, 1998, Volume: 19, Issue:10

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Female;

1998
Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction.
    Circulation, 1999, Nov-30, Volume: 100, Issue:22

    Topics: Adult; Aldosterone; Alleles; Baroreflex; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; C

1999
Effect of enalapril on plasma atrial natriuretic peptide in late recovery phase of acute myocardial infarction.
    Annals of medicine, 1991, Volume: 23, Issue:3

    Topics: Aldosterone; Atrial Natriuretic Factor; Double-Blind Method; Enalapril; Epinephrine; Female; Humans;

1991
Renal, hormonal, and hemodynamic effects of low-dose infusion of atrial natriuretic factor in acute myocardial infarction.
    American heart journal, 1990, Volume: 120, Issue:5

    Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Diuretics; Female; Hemodynamics; Humans; Infusions, In

1990
The renal response to neuroendocrine inhibition in chronic heart failure: double-blind comparison of captopril and prazosin.
    European heart journal, 1986, Volume: 7, Issue:10

    Topics: Aged; Aldosterone; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Coronary Disease; Double-Blin

1986

Other Studies

137 other studies available for aldosterone and Myocardial Infarction

ArticleYear
Primary aldosteronism presenting as embolic myocardial infarction.
    Neuro endocrinology letters, 2022, Sep-16, Volume: 43, Issue:3

    Topics: Adrenal Glands; Aldosterone; Arrhythmias, Cardiac; Embolism; Female; Humans; Hyperaldosteronism; Hyp

2022
Transient gene therapy using cell cycle factors reverses renin-angiotensin-aldosterone system activation in heart failure rat model.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:6

    Topics: Aldosterone; Animals; Cell Cycle; Heart Failure; Kidney; Myocardial Infarction; Rats; Renin; Renin-A

2023
Phosphorylation of CaMK and CREB-Mediated Cardiac Aldosterone Synthesis Induced by Arginine Vasopressin in Rats with Myocardial Infarction.
    International journal of molecular sciences, 2022, Dec-01, Volume: 23, Issue:23

    Topics: Aldosterone; Animals; Arginine Vasopressin; Collagen Type I; Endothelial Cells; Fibrosis; Heart; Myo

2022
Phosphorylation of CaMK and CREB-Mediated Cardiac Aldosterone Synthesis Induced by Arginine Vasopressin in Rats with Myocardial Infarction.
    International journal of molecular sciences, 2022, Dec-01, Volume: 23, Issue:23

    Topics: Aldosterone; Animals; Arginine Vasopressin; Collagen Type I; Endothelial Cells; Fibrosis; Heart; Myo

2022
Phosphorylation of CaMK and CREB-Mediated Cardiac Aldosterone Synthesis Induced by Arginine Vasopressin in Rats with Myocardial Infarction.
    International journal of molecular sciences, 2022, Dec-01, Volume: 23, Issue:23

    Topics: Aldosterone; Animals; Arginine Vasopressin; Collagen Type I; Endothelial Cells; Fibrosis; Heart; Myo

2022
Phosphorylation of CaMK and CREB-Mediated Cardiac Aldosterone Synthesis Induced by Arginine Vasopressin in Rats with Myocardial Infarction.
    International journal of molecular sciences, 2022, Dec-01, Volume: 23, Issue:23

    Topics: Aldosterone; Animals; Arginine Vasopressin; Collagen Type I; Endothelial Cells; Fibrosis; Heart; Myo

2022
Prognosis after discontinuing renin angiotensin aldosterone system inhibitor for heart failure with restored ejection fraction after acute myocardial infarction.
    Scientific reports, 2023, 03-02, Volume: 13, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Enzyme Inhibitors; Heart Failure; Humans; Myocardial Infarctio

2023
Role of aldosterone in mid- and long-term left ventricular remodelling after acute myocardial infarction: The REMI study.
    European journal of heart failure, 2023, Volume: 25, Issue:10

    Topics: Aldosterone; Heart Failure; Humans; Myocardial Infarction; ST Elevation Myocardial Infarction; Strok

2023
An implantable system for long-term assessment of atrial fibrillation substrate in unanesthetized rats exposed to underlying pathological conditions.
    Scientific reports, 2020, 01-17, Volume: 10, Issue:1

    Topics: Aldosterone; Animals; Atrial Fibrillation; Disease Models, Animal; Electrodes, Implanted; Fibrosis;

2020
VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism.
    Scientific reports, 2020, 12-16, Volume: 10, Issue:1

    Topics: Aldosterone; Animals; Apoptosis; Calcium Signaling; Cytochromes c; Disease Models, Animal; Fibrosis;

2020
Effect of Guanxin V in animal model of acute myocardial infarction.
    BMC complementary medicine and therapies, 2021, Feb-22, Volume: 21, Issue:1

    Topics: Aldosterone; Animals; Apoptosis; Cricetinae; Disease Models, Animal; Drugs, Chinese Herbal; Humans;

2021
Heavy metals controlling cardiovascular diseases risk factors in myocardial infarction patients in critically environmentally heavy metal-polluted steel industrial town Mandi-Gobindgarh (India).
    Environmental geochemistry and health, 2022, Volume: 44, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; C-Reactive Protein; Cardiovascular Diseases; China; Choles

2022
Aldosterone, Renin, Cardiovascular Events, and All-Cause Mortality Among African Americans: The Jackson Heart Study.
    JACC. Heart failure, 2017, Volume: 5, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Black or African American; Body Mass Index; Cardiovascu

2017
Renin and aldosterone are not associated with vulnerable plaque characteristics in patients with carotid artery disease.
    Journal of vascular surgery, 2018, Volume: 68, Issue:1

    Topics: Aged; Aldosterone; Biomarkers; Carotid Artery Diseases; Chi-Square Distribution; Endarterectomy, Car

2018
Early use of mineralocorticoid receptor antagonists in ST-elevation myocardial infarction: is it ever too early?
    Heart (British Cardiac Society), 2018, Volume: 104, Issue:22

    Topics: Aldosterone; Data Analysis; Humans; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; S

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Serum Aldosterone as Predictor of Progression of Coronary Heart Disease in Patients Without Signs of Heart Failure After Acute Myocardial Infarction.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2018, Volume: 72, Issue:6

    Topics: Aged; Aldosterone; Biomarkers; Coronary Disease; Disease Progression; Female; Follow-Up Studies; Hum

2018
Prognostic role of aldosterone in patients with acute coronary syndrome: short and medium term follow-up.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2014, Volume: 15, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aldosterone; Arrhythmias, Cardiac; Biomarkers; Chi

2014
Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; Apoptosis; Arrestins; beta-Arrestin 1; beta-Arrestin 2; beta-A

2014
Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53.
    British journal of pharmacology, 2014, Volume: 171, Issue:15

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Cells, Cul

2014
A comparison of the efficacy of surgical renal denervation and pharmacologic therapies in post-myocardial infarction heart failure.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angioten

2014
Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Oct-01, Volume: 307, Issue:7

    Topics: Aldosterone; Animals; Apoptosis; Caspase 3; Disease Models, Animal; Eplerenone; Macrophages; Male; M

2014
Different potencies of angiotensin receptor blockers at suppressing adrenal β-Arrestin1-dependent post-myocardial infarction hyperaldosteronism.
    Journal of the American College of Cardiology, 2014, Dec-30, Volume: 64, Issue:25

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; H

2014
Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats.
    Planta medica, 2015, Volume: 81, Issue:7

    Topics: Aldosterone; Animals; Antioxidants; Captopril; Collagen; Coronary Occlusion; Coronary Vessels; Endot

2015
Rapid and MR-Independent IK1 Activation by Aldosterone during Ischemia-Reperfusion.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Aldosterone; Animals; Female; Heart Ventricles; Male; Membrane Potentials; Myocardial Contraction; M

2015
Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community.
    JACC. Heart failure, 2016, Volume: 4, Issue:10

    Topics: Adult; Aged; Aldosterone; C-Reactive Protein; Coronary Artery Disease; Diabetes Mellitus; Female; He

2016
Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure.
    Journal of the American Heart Association, 2017, 01-10, Volume: 6, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Aldosterone; Amides; Angina, Unstable; Anticholesteremic Agents; Card

2017
Central infusion of aldosterone synthase inhibitor attenuates left ventricular dysfunction and remodelling in rats after myocardial infarction.
    Cardiovascular research, 2009, Feb-15, Volume: 81, Issue:3

    Topics: Aldosterone; Animals; Cardiac Catheterization; Corticosterone; Cytochrome P-450 CYP11B2; Disease Mod

2009
Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction.
    European heart journal, 2008, Volume: 29, Issue:20

    Topics: Aldosterone; Atrial Natriuretic Factor; Biomarkers; Female; Follow-Up Studies; Hospital Mortality; H

2008
The measurement of plasma aldosterone in patients post-myocardial infarction.
    European heart journal, 2008, Volume: 29, Issue:20

    Topics: Aldosterone; Biomarkers; Humans; Myocardial Infarction; Potassium; Receptors, Mineralocorticoid

2008
[Mechanisms of losartan for inhibition of myocardial fibrosis following myocardial infarction in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:12

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Fibrosis; Losartan; M

2008
Aldosterone and long-term outcome after myocardial infarction: A substudy of the french nationwide Observatoire sur la Prise en charge hospitalière, l'Evolution à un an et les caRactéristiques de patients présentant un infArctus du myocarde avec ou sans o
    American heart journal, 2009, Volume: 157, Issue:4

    Topics: Aldosterone; Female; Follow-Up Studies; France; Humans; Male; Middle Aged; Myocardial Infarction; Pr

2009
Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:6

    Topics: Aldosterone; Angina, Unstable; Animals; Apoptosis; Dexamethasone; Glucocorticoids; Hormone Antagonis

2009
Aldosterone inhibition and cardiovascular protection: more important than it once appeared.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:4

    Topics: Aldosterone; Atherosclerosis; Blood Vessels; Cardiomegaly; Cardiotonic Agents; Endothelium; Heart Fa

2010
Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.
    Journal of the American College of Cardiology, 2011, Jan-18, Volume: 57, Issue:3

    Topics: Adrenal Glands; Aldosterone; Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Cell Line; Disease

2011
Prognostic value of plasma renin activity in heart failure.
    The American journal of cardiology, 2011, Jul-15, Volume: 108, Issue:2

    Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bioma

2011
[The EMPHASIS-HF study].
    Giornale italiano di cardiologia (2006), 2011, Volume: 12, Issue:5

    Topics: Aldosterone; Biomarkers; Canrenone; Cause of Death; Double-Blind Method; Early Termination of Clinic

2011
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure.
    European heart journal, 2012, Volume: 33, Issue:2

    Topics: Age Factors; Aged; Aldosterone; Angioplasty, Balloon, Coronary; Body Mass Index; Brain Ischemia; C-R

2012
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
    Nature medicine, 2011, Nov-13, Volume: 17, Issue:12

    Topics: Aldosterone; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiotoxins; Cells, Cultu

2011
Benidipine reduces ischemia reperfusion-induced systemic oxidative stress through suppression of aldosterone production in mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:3

    Topics: Aldosterone; Animals; Apoptosis; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal;

2012
Role of aldosterone on lung structural remodelling and right ventricular function in congestive heart failure.
    BMC cardiovascular disorders, 2011, Dec-02, Volume: 11

    Topics: Aldosterone; Animals; Cell Proliferation; Echocardiography; Heart Failure; Hypertension, Pulmonary;

2011
Effect of direct renin inhibitor, aliskiren, on peripheral blood monocyte subsets and myocardial salvage in patients with primary acute myocardial infarction.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:6

    Topics: Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In

2012
Update on aldosterone antagonists use in heart failure with reduced left ventricular ejection fraction. Heart Failure Society of America Guidelines Committee.
    Journal of cardiac failure, 2012, Volume: 18, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Eplerenone; Heart; Heart Failure; Ho

2012
Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cel

2012
Inhibition of brain angiotensin III attenuates sympathetic hyperactivity and cardiac dysfunction in rats post-myocardial infarction.
    Cardiovascular research, 2013, Mar-01, Volume: 97, Issue:3

    Topics: Aldosterone; Angiotensin III; Animals; Baroreflex; Blood Pressure; Brain; Disease Models, Animal; Di

2013
New treatments for myocardial fibrosis.
    Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Canrenone; Clinical Trials as Topic;

2002
Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure.
    Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3

    Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Collagen; Cyclodextrins; Disease Models, Anim

2002
Aldosterone blockade and heart failure.
    The New England journal of medicine, 2003, Apr-03, Volume: 348, Issue:14

    Topics: Aldosterone; Eplerenone; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Myocardial I

2003
Expression and modulation of steroidogenic acute regulatory protein messenger ribonucleic acid in rat cardiocytes and after myocardial infarction.
    Endocrinology, 2003, Volume: 144, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Cells, Cultured; Dexamethasone; Gene Expression; Glucocorticoi

2003
[Cytokines and remodeling of the heart in patients with congestive heart failure].
    Polskie Archiwum Medycyny Wewnetrznej, 2003, Volume: 109, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Cardiomyopathy, Dilated; Catecholam

2003
[Aldosteronuria and blood and urinary electrolyte balance in myocardial infarct in its recent phase].
    Bollettino della Societa italiana di cardiologia, 1962, Volume: 7

    Topics: Aldosterone; Humans; Myocardial Infarction; Urinary Tract; Water-Electrolyte Balance

1962
[Effect of aldosterone loading on natriuresis in normal subjects and in the post-infarct period].
    Atti della Societa italiana di cardiologia, 1962, Volume: 22(2)

    Topics: Aldosterone; Humans; Myocardial Infarction; Natriuresis

1962
[Behavior of aldosteronuria and natriuria in the immediate post-infarct period].
    Atti della Societa italiana di cardiologia, 1962, Volume: 22(2)

    Topics: Aldosterone; Humans; Myocardial Infarction; Natriuresis

1962
[Pressure of the tissues in various post-infarct complications and under the influence of aldosterone, spirolactone and saline administration].
    Atti della Societa italiana di cardiologia, 1962, Volume: 22(2)

    Topics: Aldosterone; Heart Failure; Humans; Myocardial Infarction; Sodium Chloride; Spironolactone

1962
STEROIDS PRODUCED IN VITRO BY ADRENAL GLANDS OF NORMAL AND ARTERIOSCLEROTIC RATS DURING AND AFTER DRUG-INDUCED MYOCARDIAL NECROSIS.
    Circulation research, 1965, Volume: 16

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Arteriosclerosis; Heart Failure; In Vitro Tech

1965
Pathophysiological aspects of experimental myocardial infarction during arterial hypertension.
    Bulletin of experimental biology and medicine, 2003, Volume: 136, Issue:5

    Topics: Adult; Aldosterone; Animals; Blood Pressure; Case-Control Studies; Disease Models, Animal; Humans; H

2003
Direct and indirect effects of aldosterone on cyclooxygenase-2 and interleukin-6 expression in rat cardiac cells in culture and after myocardial infarction.
    Endocrinology, 2004, Volume: 145, Issue:7

    Topics: Aldosterone; Animals; Biomarkers; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Gene

2004
Effects of differential blockade of the renin-angiotensin system in postinfarcted rats.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:3

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim

2004
Inhibition of Na+-H+ exchange by cariporide reduces inflammation and heart failure in rabbits with myocardial infarction.
    British journal of pharmacology, 2004, Volume: 142, Issue:7

    Topics: Aldosterone; Animals; C-Reactive Protein; Electrocardiography; Guanidines; Heart Failure; Inflammati

2004
Adrenomedullin administration immediately after myocardial infarction ameliorates progression of heart failure in rats.
    Circulation, 2004, Jul-27, Volume: 110, Issue:4

    Topics: Adrenomedullin; Aldosterone; Animals; Body Weight; Dinoprost; Disease Progression; Drug Evaluation,

2004
Critical role of CNS effects of aldosterone in cardiac remodeling post-myocardial infarction in rats.
    Cardiovascular research, 2004, Dec-01, Volume: 64, Issue:3

    Topics: Administration, Oral; Aldosterone; Animals; Central Nervous System; Collagen; Epinephrine; Injection

2004
Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist.
    Journal of cardiovascular pharmacology, 2005, Volume: 45, Issue:1

    Topics: Adrenergic beta-Agonists; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anim

2005
[Aldosterone and aldosterone antagonists. Eplerenone in cardiac insufficiency after myocardial infarction].
    Medizinische Monatsschrift fur Pharmazeuten, 2005, Volume: 28, Issue:3

    Topics: Aldosterone; Cardiac Output, Low; Eplerenone; Humans; Mineralocorticoid Receptor Antagonists; Myocar

2005
Persistent cardiac aldosterone synthesis in angiotensin II type 1A receptor-knockout mice after myocardial infarction.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Gene Expression Regulation; Male; Mice; Mice, Knocko

2005
Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
    Journal of molecular and cellular cardiology, 2005, Volume: 39, Issue:3

    Topics: Aldosterone; Angiotensinogen; Animals; Animals, Genetically Modified; Brain; Cell Size; Fibronectins

2005
Progressive left ventricular hypertrophy after withdrawal of long-term ACE inhibition following experimental myocardial infarction.
    European journal of heart failure, 2006, Volume: 8, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Endothelium, Vascular; Hypertrophy,

2006
Animal models of cardiac fibrosis.
    Methods in molecular medicine, 2005, Volume: 117

    Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Diseases;

2005
Expression of procollagen C-proteinase enhancer-1 in the remodeling rat heart is stimulated by aldosterone.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:3

    Topics: Aldosterone; Animals; Body Weight; Collagen Type I; Glycoproteins; Heart; In Situ Hybridization; Int

2006
Improvement of EDHF by chronic ACE inhibition declines rapidly after withdrawal in rats with myocardial infarction.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:6

    Topics: Acetylcholine; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Factors; E

2005
Cardioprotective effects of eplerenone in the rat heart: interaction with locally synthesized or blood-derived aldosterone?
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:4

    Topics: Aldosterone; Animals; Cardiotonic Agents; Drug Interactions; Eplerenone; Heart; Hemodynamics; In Vit

2006
Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients.
    American heart journal, 2006, Volume: 152, Issue:2

    Topics: Aged; Aldosterone; AMP Deaminase; Angiotensin II; Atrial Natriuretic Factor; Endothelin-1; Epinephri

2006
High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction.
    Circulation, 2006, Dec-12, Volume: 114, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Electrocardiography; Female; Follow-Up Studies; Humans;

2006
Effects of eplerenone and salt intake on left ventricular remodeling after myocardial infarction in rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:8

    Topics: Aldosterone; Animals; Cardiomegaly; Diet, Sodium-Restricted; Echocardiography; Eplerenone; Fibrosis;

2006
Aldosterone and cardiovascular disease: smoke and fire.
    Circulation, 2006, Dec-12, Volume: 114, Issue:24

    Topics: Aldosterone; Cardiovascular Diseases; Electrocardiography; Humans; Hyperaldosteronism; Hypertension;

2006
Avoiding vicious circles: mineralocorticoid receptor antagonism prevents vascular oxidative stress early after myocardial infarction.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Endothelium, Vascular; Eplerenone; Humans; Mice; Mineralocorti

2007
Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:4

    Topics: Aldosterone; Animals; Clodronic Acid; Collagen; Cytokines; Eplerenone; Factor XIIIa; Heart Failure;

2008
Effects of captopril in acute and chronic heart failure. Correlations with plasma levels of noradrenaline, renin, and aldosterone.
    British heart journal, 1983, Volume: 49, Issue:1

    Topics: Aged; Aldosterone; Captopril; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Male; Mi

1983
The renin-angiotensin--aldosterone system and the clinical course of acute myocardial infarction.
    European heart journal, 1983, Volume: 4, Issue:4

    Topics: Adult; Aged; Aldosterone; Arrhythmias, Cardiac; Epinephrine; Female; Heart Failure; Humans; Male; Mi

1983
Flurbiprofen interaction with single doses of atenolol and propranolol.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:6

    Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Body Weight; Female; Flurbiprofen; Heart Rate; Humans;

1984
[Aldosterone, sodium and potassium concentrations in the blood of patients with myocardial infarction after acute hydrocortisone load].
    Kardiologiia, 1983, Volume: 23, Issue:9

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hydrocortisone; Male; Middle Aged; Myocardial Infarction;

1983
Humoral mechanisms of arterial hypertension in patients in the acute phase of myocardial infarction.
    Cor et vasa, 1982, Volume: 24, Issue:5

    Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Hemodynamics; Humans; Hydrocortisone; Hypertension

1982
Effect of enalapril on ventricular remodeling and function during healing after anterior myocardial infarction in the dog.
    Circulation, 1995, Feb-01, Volume: 91, Issue:3

    Topics: Aldosterone; Animals; Collagen; Dogs; Enalapril; Female; Hemodynamics; Male; Myocardial Infarction;

1995
Selective activation of atrial natriuretic peptide in patients with myocardial infarction and mild left ventricular dysfunction.
    International journal of cardiology, 1993, Dec-15, Volume: 42, Issue:2

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Male; Middle Aged; Myocardial I

1993
Atrial natriuretic peptide response is blunted in patients with acute myocardial infarction and mild left ventricular dysfunction.
    Cardiology, 1994, Volume: 84, Issue:2

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output, Low; Female; He

1994
Short- and long-term neurohormonal activation following acute myocardial infarction.
    American heart journal, 1993, Volume: 126, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Case-Control

1993
Plasma atrial natriuretic factor in uncomplicated acute myocardial infarction.
    Cardiology, 1993, Volume: 83, Issue:3

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Female; Hemodynamics; Humans; Male; Middle Aged

1993
[Effect of cilazapril on exercise tolerance and neurohumoral factors in patients with asymptomatic chronic heart failure after myocardial infarction].
    Journal of cardiology, 1995, Volume: 26, Issue:5

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Fact

1995
Collagen scar formation after acute myocardial infarction: relationships to infarct size, left ventricular function, and coronary artery patency.
    Circulation, 1997, Oct-21, Volume: 96, Issue:8

    Topics: Adult; Aged; Aldosterone; Cicatrix; Cineangiography; Collagen; Coronary Angiography; Coronary Vessel

1997
Adrenal tumors and pregnancy.
    World journal of surgery, 1999, Volume: 23, Issue:2

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Fatal Outc

1999
Activation of cardiac aldosterone production in rat myocardial infarction: effect of angiotensin II receptor blockade and role in cardiac fibrosis.
    Circulation, 1999, May-25, Volume: 99, Issue:20

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; C

1999
[Role of cardiac aldosterone in post-infarction ventricular remodeling in rats].
    Archives des maladies du coeur et des vaisseaux, 1999, Volume: 92, Issue:8

    Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Myocardial Infarction; Rats; Reverse Transcriptase P

1999
Neurohormones in an ovine model of compensated postinfarction left ventricular dysfunction.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:3

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Coronary Vessels; Disease Models, Animal; Endotheli

2000
[Changes in gluco- and mineralocorticoid adrenal functions in rats with inherited arterial hypertension during experimental myocardial infarction].
    Biulleten' eksperimental'noi biologii i meditsiny, 2000, Volume: 129, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Corticosterone; Hypertension; Male; Myocardial Infarction; Rat

2000
The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study.
    Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:1

    Topics: Aldosterone; Double-Blind Method; Eplerenone; Heart Failure; Humans; Mineralocorticoid Receptor Anta

2001
Usefulness of carperitide for the treatment of refractory heart failure due to severe acute myocardial infarction.
    Japanese heart journal, 2001, Volume: 42, Issue:3

    Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Bronchodilator Agents; Female; Heart F

2001
Relationship between transcardiac extraction of aldosterone and left ventricular remodeling in patients with first acute myocardial infarction: extracting aldosterone through the heart promotes ventricular remodeling after acute myocardial infarction.
    Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5

    Topics: Acute Disease; Aged; Aldosterone; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhi

2001
Aldosterone and myocardial infarction--are aldosterone antagonists needed to prevent remodelling or does ACE inhibition suffice?
    Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Canrenoic Acid; Captopril; Cardiomegaly; Huma

2001
Effects of long-term enalapril and losartan therapy of heart failure on cardiovascular aldosterone.
    Journal of endocrinological investigation, 2002, Volume: 25, Issue:5

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low;

2002
[Disorder of the mineralocorticoid function of the adrenals in the acute period of myocardial infarct and the ways for its correction].
    Sovetskaia meditsina, 1979, Issue:1

    Topics: Acute Disease; Adrenal Gland Diseases; Adult; Aged; Aldosterone; Chronic Disease; Coronary Disease;

1979
[Renin and various factors of its regulation in acute myocardial infarct].
    Kardiologiia, 1978, Volume: 18, Issue:5

    Topics: Acute Disease; Adult; Aged; Aldosterone; Angiotensin II; Homeostasis; Humans; Hypokalemia; Male; Mid

1978
[Activity of adrenal hormones and kallikrein-kinin blood system in acute disorders of the heart rhythm in patients with myocardial infarct].
    Sovetskaia meditsina, 1978, Issue:9

    Topics: 11-Hydroxycorticosteroids; Acute Disease; Adult; Aged; Aldosterone; Arrhythmias, Cardiac; Epinephrin

1978
[Functional morphology of the hypothalamo-hypophyseal neurosecretory system and adrenal cortex in myocardial infarct].
    Arkhiv patologii, 1977, Volume: 39, Issue:8

    Topics: Adrenal Cortex; Aldosterone; Cell Nucleus; Dihydrolipoamide Dehydrogenase; Glutamate Dehydrogenase;

1977
[Evaluation of the adrenal cortex function in patients with acute myocardial infarct by means of radioisotope micromethods].
    Kardiologiia, 1976, Volume: 16, Issue:4

    Topics: Acute Disease; Adrenal Cortex; Adrenal Glands; Aldosterone; Binding, Competitive; Humans; Hydrocorti

1976
[Certain humoral factors in acute myocardial infarct complicated by cardiogenic shock].
    Kardiologiia, 1975, Volume: 15, Issue:4

    Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Humans; Male; Middle Aged; Myocardial Infarction;

1975
[Changes in the levels of atrial natriuretic factor, aldosterone, cyclic nucleotides and beta 2-microglobulin in patients with myocardial infarction after ultrasonic therapy].
    Kardiologiia, 1991, Volume: 31, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; beta 2-Microglobulin; Cardiomyopathy, Dilated; Cyclic

1991
[The changes in renin-angiotensin-aldosterone system in acute myocardial infarction and the effects of converting enzyme inhibitor-captopril].
    Zhonghua xin xue guan bing za zhi, 1991, Volume: 19, Issue:6

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Captopril; Female; Humans; Male; Middle Aged; Myocardial I

1991
Abnormal hormonal and renal responses to saline load in hypertensive patients with parental history of cardiovascular accidents.
    Circulation, 1991, Volume: 84, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cerebrovascular Disorders; Family Hea

1991
Atrial natriuretic peptide in patients with acute myocardial infarction without functional heart failure.
    European heart journal, 1991, Volume: 12, Issue:4

    Topics: Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Catecholamines; Female; Heart Failure;

1991
[Changes in PTCA. A model of ischemia in humans].
    Acta medica Austriaca. Supplement, 1991, Volume: 42

    Topics: Adenosine Triphosphate; Adult; Aged; Aldosterone; Angina Pectoris; Angioplasty, Balloon, Coronary; A

1991
Transient acute myocardial ischemia increases atrial natriuretic peptide release in men.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Exercise Test; Humans; Male; Middle Aged; Myocardial

1991
Effects of routine heparin therapy on plasma aldosterone concentration.
    Acta endocrinologica, 1991, Volume: 124, Issue:3

    Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Embolism; Female; Heparin; Humans; Male; Myocardial

1991
[Renin and aldosterone in the first 24 hours after acute myocardial infarct].
    Vnitrni lekarstvi, 1991, Volume: 37, Issue:6

    Topics: Aldosterone; Female; Humans; Male; Middle Aged; Myocardial Infarction; Renin; Time Factors

1991
Role of left ventricular dysfunction in selective neurohumoral activation in the recovery phase of anterior wall acute myocardial infarction.
    The American journal of cardiology, 1990, Sep-01, Volume: 66, Issue:5

    Topics: Aged; Aldosterone; Angiotensin II; Cardiac Catheterization; Diuretics; Female; Hemodynamics; Humans;

1990
Plasma atrial natriuretic factor in low output heart failure syndromes.
    Klinische Wochenschrift, 1990, Mar-16, Volume: 68, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Bradycardia; Cardiac Output, Low; Femal

1990
Plasma atrial natriuretic factor in patients with acute myocardial infarction.
    European heart journal, 1990, Volume: 11, Issue:9

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Humans; Male; Middle Aged; Myocardial Contraction; My

1990
[Changes in renin activity in patients with acute myocardial infarction].
    Zhonghua xin xue guan bing za zhi, 1990, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Male; Middle Aged; Myocardial Infarctio

1990
Trace element-hormone-relations in the early course of myocardial infarction.
    Zeitschrift fur medizinische Laboratoriumsdiagnostik, 1990, Volume: 31, Issue:3

    Topics: Aldosterone; Copper; Humans; Hydrocortisone; Myocardial Infarction; Trace Elements; Triiodothyronine

1990
[Atrial natriuretic factor in cardiogenic shock, in hypovolemic shock and in the bradycardia-hypotension syndrome following acute myocardial infarction].
    Giornale italiano di cardiologia, 1989, Volume: 19, Issue:8

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Bradycardia; Cardiac Output, Low; Female; Hemod

1989
[Effect of an early single physical load on hemodynamics and plasma aldosterone level in patients with acute myocardial infarction].
    Kardiologiia, 1989, Volume: 29, Issue:4

    Topics: Adult; Aldosterone; Exercise Therapy; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction

1989
Neurohumoral responses to chronic myocardial infarction in rats.
    Circulation, 1988, Volume: 78, Issue:2

    Topics: Aldosterone; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Catecholamines; Chronic Disea

1988
Neuroendocrine changes in acute myocardial infarction.
    The American journal of medicine, 1988, Mar-11, Volume: 84, Issue:3A

    Topics: Aldosterone; Arginine Vasopressin; Captopril; Catecholamines; Humans; Myocardial Infarction; Neurose

1988
[Determination of the cortisol, insulin and aldosterone content of the blood as possible indices of the course and prognosis of myocardial infarct].
    Kardiologiia, 1986, Volume: 26, Issue:7

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Myocardial Inf

1986
Hyperkalemic left bundle branch block and hyporeninemic hypoaldosteronism (hyperkalemic left bundle branch block).
    Journal of electrocardiology, 1986, Volume: 19, Issue:1

    Topics: Aged; Aldosterone; Bundle-Branch Block; Diagnosis, Differential; Female; Humans; Hyperkalemia; Kidne

1986
Effect of dilazep on hemoglobin-oxygen affinity in patients with ischemic heart disease.
    Japanese heart journal, 1985, Volume: 26, Issue:4

    Topics: 2,3-Diphosphoglycerate; Administration, Oral; Adult; Aged; Aldosterone; Angina Pectoris; Azepines; C

1985
[Neurohumoral aspects of myocardial infarct and its complications].
    Kardiologiia, 1974, Volume: 14, Issue:4

    Topics: 17-Ketosteroids; Adrenal Glands; Adult; Aged; Aldosterone; Epinephrine; Female; Heart Failure; Hemod

1974
Essential hypertension: renin and aldosterone, heart attack and stroke.
    The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9

    Topics: Adult; Aldosterone; Cardiomegaly; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Mid

1972
Role of catecholamines, aldosterone, potassium and lipids in pathophysiology and severity of myocardial infarction-a clinical and experimental study.
    The Journal of the Association of Physicians of India, 1974, Volume: 22, Issue:8

    Topics: Aldosterone; Animals; Arteriosclerosis; Catecholamines; Coronary Disease; Dogs; Humans; Lipids; Myoc

1974
Pathophysiologic changes in arteriosclerotic and nonarteriosclerotic rats, following isoproterenol-induced myocardial infarction.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Adrenal Glands; Alanine Transaminase; Aldosterone; Animals; Arteriosclerosis; Aspartate Aminotransfe

1972
[Activity of plasma renin and aldosterone excretion in patients with macrofocal myocardial infarct and its complications].
    Kardiologiia, 1973, Volume: 13, Issue:6

    Topics: Adult; Aged; Aldosterone; Arrhythmias, Cardiac; Female; Humans; Juxtaglomerular Apparatus; Male; Mid

1973
[Biosynthesis of glucocorticoids and mineralocorticoids in dogs' adrenals in experimental myocardial infarct].
    Kardiologiia, 1973, Volume: 13, Issue:6

    Topics: Adrenal Glands; Aldosterone; Animals; Coronary Vessels; Corticosterone; Cortisone; Desoxycorticoster

1973
Isolation and characterization of a sodium retaining substance from pig heart muscle and its role in myocardial infarction.
    The Indian journal of medical research, 1971, Volume: 59, Issue:3

    Topics: Aldosterone; Animals; Diuresis; Myocardial Infarction; Myocardium; Potassium; Sodium; Swine

1971
Metabolic and histopathological consequences of a fatty liver during the acute stages of myocardial infarction in rats.
    British journal of experimental pathology, 1971, Volume: 52, Issue:5

    Topics: Acute Disease; Adrenal Glands; Alanine Transaminase; Aldosterone; Animals; Aspartate Aminotransferas

1971
[Hormonal activity of the adrenals in congestive circulatory insufficiency].
    Kardiologiia, 1971, Volume: 11, Issue:12

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult; Aged; Aldosterone; Cortis

1971
[Some hormonal parameters in the course of myocardial infarct].
    Bollettino della Societa italiana di cardiologia, 1971, Volume: 16, Issue:7

    Topics: Adrenal Glands; Adrenal Medulla; Adult; Aged; Aldosterone; Catecholamines; Humans; Hydrocortisone; M

1971
Role of aldosterone in myocardial infarction.
    Annals of the New York Academy of Sciences, 1965, Jan-20, Volume: 118, Issue:11

    Topics: Adult; Aldosterone; Animals; Chromatography; Diet, Sodium-Restricted; Dogs; Humans; Male; Myocardial

1965
[Blood gas and acid-base equilibrium in myocardial infarct].
    Die Medizinische Welt, 1970, Oct-24, Volume: 43

    Topics: Acid-Base Equilibrium; Aldosterone; Alkalosis; Carbon Dioxide; Humans; Myocardial Infarction; Oxygen

1970
[Characteristics of hormonal disorders in myocardial infarct].
    Klinicheskaia meditsina, 1970, Volume: 48, Issue:8

    Topics: 17-Hydroxycorticosteroids; Aldosterone; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Hydro

1970
Role of sodium-retaining hormones in cardiac control.
    Indian journal of experimental biology, 1970, Volume: 8, Issue:4

    Topics: Aldosterone; Animals; Dogs; Myocardial Infarction; Myocardium; Sodium; Stress, Physiological; Swine;

1970
[Changes of aldosteronuria and tetrahydroaldosteronuria in the post-infarct period].
    Minerva medica, 1968, Jun-23, Volume: 59, Issue:50

    Topics: Adult; Aged; Aldosterone; Female; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis

1968
[The increase of aldosterone in vascular shock].
    Folia endocrinologica, 1966, Volume: 19, Issue:1

    Topics: Adult; Aged; Aldosterone; Cerebral Hemorrhage; Female; Humans; Intracranial Embolism and Thrombosis;

1966