Page last updated: 2024-11-07

aldosterone and Mitral Valve Insufficiency

aldosterone has been researched along with Mitral Valve Insufficiency in 16 studies

Mitral Valve Insufficiency: Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.

Research Excerpts

ExcerptRelevanceReference
"The effects of sacubitril/valsartan (S/V) on the renin-angiotensin-aldosterone system (RAAS) in dogs with cardiomegaly secondary to myxomatous mitral valve disease (MMVD) are currently unknown."9.27A prospective, randomized, double-blind, placebo-controlled pilot study of sacubitril/valsartan (Entresto) in dogs with cardiomegaly secondary to myxomatous mitral valve disease. ( Duran, SH; Jung, S; Newhard, DK; Winter, RL, 2018)
"The effects of sacubitril/valsartan (S/V) on the renin-angiotensin-aldosterone system (RAAS) in dogs with cardiomegaly secondary to myxomatous mitral valve disease (MMVD) are currently unknown."5.27A prospective, randomized, double-blind, placebo-controlled pilot study of sacubitril/valsartan (Entresto) in dogs with cardiomegaly secondary to myxomatous mitral valve disease. ( Duran, SH; Jung, S; Newhard, DK; Winter, RL, 2018)
"Pimobendan has a dual mechanism of action: it increases myocardial contractility by increasing calcium sensitization to troponin C and it promotes vasodilation by inhibiting PDEIII."1.34Effects of pimobendan for mitral valve regurgitation in dogs. ( Hara, A; Kanno, N; Kano, R; Kawasaki, M; Kuse, H; Sasaki, Y, 2007)
"Furosemide was added after the 3-week examination, and at 6 months, dogs had received furosemide for at least 4 months."1.29Effects of long-term treatment with enalapril or hydralazine on the renin-angiotensin-aldosterone system and fluid balance in dogs with naturally acquired mitral valve regurgitation. ( Häggström, J; Hansson, K; Karlberg, BE; Kvart, C; Madej, A; Olsson, K, 1996)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Newhard, DK1
Jung, S1
Winter, RL1
Duran, SH1
Yata, M1
Kooistra, HS1
Beijerink, NJ1
Yiu, KH1
Ng, WS1
Chan, D1
Sit, KY1
Wong, A1
Lee, CW1
Chum, HL1
Cheng, WY1
Pun, CT1
Ho, KL1
Chen, Y1
Ho, LM1
Kumana, CR1
Cheung, HL1
Chung, MC1
Lau, CP1
Au, WK1
Tse, HF1
KUKES, VG1
BOJS, GE1
CONN, HL2
Kanno, N1
Kuse, H1
Kawasaki, M1
Hara, A1
Kano, R1
Sasaki, Y1
Pedersen, HD2
Häggström, J2
Hansson, K2
Karlberg, BE2
Kvart, C2
Madej, A1
Olsson, K2
Vuolteenaho, O1
Olsen, LH1
Mow, T1
Christensen, NJ1
Kopylova, VA1
Giliazutdinova, ZSh1
Novikov, VM1
Prachar, H1
Amano, Y1
Abe, T1
Matsui, N1
Genest, J1
Granger, P1
De Champlain, J1
Boucher, R1
Kinoshita, M1
Detweiler, DK1
McGiff, J1
Luchi, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Beneficio Del Bloqueo Del Sistema Renina-angiotensina Sobre la evolución clínica y el Remodelado Ventricular Tras la colocación de Una prótesis percutánea aórtica (RASTAVI)[NCT03201185]Phase 4194 participants (Actual)Interventional2018-02-10Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aldosterone and Mitral Valve Insufficiency

ArticleYear
Endocrine factors in congestive heart failure.
    The American journal of cardiology, 1968, Volume: 22, Issue:1

    Topics: Aged; Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Do

1968

Trials

1 trial available for aldosterone and Mitral Valve Insufficiency

ArticleYear
A prospective, randomized, double-blind, placebo-controlled pilot study of sacubitril/valsartan (Entresto) in dogs with cardiomegaly secondary to myxomatous mitral valve disease.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:5

    Topics: Aldosterone; Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pr

2018

Other Studies

14 other studies available for aldosterone and Mitral Valve Insufficiency

ArticleYear
Cardiorenal and endocrine effects of synthetic canine BNP1-32 in dogs with compensated congestive heart failure caused by myxomatous mitral valve disease.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:2

    Topics: Aldosterone; Animals; Cross-Over Studies; Dog Diseases; Dogs; Furosemide; Heart Failure; Heart Valve

2019
Improved prognosis following renin-angiotensin-aldosterone system blockade in patients undergoing concomitant aortic and mitral valve replacement.
    International journal of cardiology, 2014, Dec-15, Volume: 177, Issue:2

    Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aorti

2014
[ON USE OF THE BLOCKING AGENT ALDOSTERONE].
    Klinicheskaia meditsina, 1963, Volume: 41

    Topics: Aldosterone; Aortic Valve; Diuretics; Heart Failure; Humans; Hyperaldosteronism; Mitral Valve Insuff

1963
DISTRIBUTION OF BODY SODIUM, POTASSIUM, AND WATER AND THE EXCRETION OF ALDOSTERONE IN DOGS WITH SPONTANEOUS HEART FAILURE.
    American heart journal, 1965, Volume: 69

    Topics: Aldosterone; Animals; Ascites; Dog Diseases; Dogs; Edema; Heart Failure; Humans; Mitral Valve Insuff

1965
Effects of pimobendan for mitral valve regurgitation in dogs.
    The Journal of veterinary medical science, 2007, Volume: 69, Issue:4

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiotonic Agents; Catecholamines;

2007
Effects of mild mitral valve insufficiency, sodium intake, and place of blood sampling on the renin-angiotensin system in dogs.
    Acta veterinaria Scandinavica, 1996, Volume: 37, Issue:1

    Topics: Aldosterone; Animals; Controlled Clinical Trials as Topic; Diet, Sodium-Restricted; Dog Diseases; Do

1996
Effects of long-term treatment with enalapril or hydralazine on the renin-angiotensin-aldosterone system and fluid balance in dogs with naturally acquired mitral valve regurgitation.
    American journal of veterinary research, 1996, Volume: 57, Issue:11

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Dog Dis

1996
Effects of naturally acquired decompensated mitral valve regurgitation on the renin-angiotensin-aldosterone system and atrial natriuretic peptide concentration in dogs.
    American journal of veterinary research, 1997, Volume: 58, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Dog Dis

1997
Neuroendocrine changes in Dachshunds with mitral valve prolapse examined under different study conditions.
    Research in veterinary science, 1999, Volume: 66, Issue:1

    Topics: Aldosterone; Animals; Dog Diseases; Dogs; Eating; Epinephrine; Fasting; Humans; Hydrocortisone; Magn

1999
[Mineralocorticoid function of the adrenal cortex in pregnancies complicated by mitral valve disease and pulmonary edema].
    Akusherstvo i ginekologiia, 1979, Issue:11

    Topics: Adrenal Cortex; Adult; Aldosterone; Female; Humans; Mitral Valve Insufficiency; Pregnancy; Pregnancy

1979
[Changes in PTCA. A model of ischemia in humans].
    Acta medica Austriaca. Supplement, 1991, Volume: 42

    Topics: Adenosine Triphosphate; Adult; Aged; Aldosterone; Angina Pectoris; Angioplasty, Balloon, Coronary; A

1991
[Mitral valve disease and atrial natriuretic polypeptide].
    Nihon Geka Gakkai zasshi, 1987, Volume: 88, Issue:7

    Topics: Aldosterone; Atrial Natriuretic Factor; Extracorporeal Circulation; Heart Valve Prosthesis; Humans;

1987
Studies on cardiac output to blood volume, and renal circulation in chronic congestive heart failure.
    Japanese circulation journal, 1968, Volume: 32, Issue:3

    Topics: Adult; Aged; Aldosterone; Arteriosclerosis; Blood Pressure; Blood Volume; Cardiac Output; Chronic Di

1968
Why we have gone to the dogs.
    Transactions of the American Clinical and Climatological Association, 1966, Volume: 77

    Topics: Aldosterone; Animals; Cardiac Output; Dog Diseases; Dogs; Exercise Test; Guanethidine; Heart; Heart

1966