Page last updated: 2024-11-07

aldosterone and Kidney Failure

aldosterone has been researched along with Kidney Failure in 27 studies

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"Bradykinin (BK) is a potent vasoactive peptide that may also participate in this model."5.31Intrarenal angiotensin and bradykinin peptide levels in the remnant kidney model of renal insufficiency. ( Campbell, DJ; Mackie, FE; Meyer, TW, 2001)
"In the presence of renal insufficiency, the ARB valsartan did not raise serum [K(+)] to the same degree as the ACE inhibitor lisinopril."5.09ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group. ( Agarwal, R; Bakris, GL; Bolton, WK; Catanzaro, D; Hebert, L; Janssen, I; Richardson, D; Siomos, M, 2000)
"Treatment with midodrine and albumin was associated with a slight but significant decrease in plasma renin activity and aldosterone compared to placebo (renin -4."2.87Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial. ( Ariza, X; Castellote, J; Colmenero, J; Córdoba, J; de Prada, G; Fabrellas, N; Garcia-Martínez, R; Ginès, P; Graupera, I; Guevara, M; Huelin, P; Lopez Benaiges, E; Manríquez, M; Márquez, F; Martín-Llahí, M; Moreira, R; Navasa, M; Nazar, A; Pavesi, M; Pose, E; Simón-Talero, M; Solà, E; Solé, C; Suñé, P; Torrens, M; Vargas, V; Ventura, M; Xiol, X, 2018)
"Hypertension is a major risk factor for progressive renal disease."2.41Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift. ( Epstein, M, 2001)
"Liver cirrhosis is associated to circulatory abnormalities leading to hypovolemia and stimulation of the renin-angiotensin-aldosterone system (RAAS)."1.91Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression. ( Alvarez de la Rosa, D; González-Alayón, C; Hernández, G; Hernández-Guerra, M; Porrini, E; Rodríguez-Rodríguez, AE; Serrano-Morillas, N; Vastola-Mascolo, A, 2023)
"Aldosterone was 1."1.34The renin-angiotensin system in malignant hypertension revisited: plasma renin activity, microangiopathic hemolysis, and renal failure in malignant hypertension. ( Koopmans, RP; van den Born, BJ; van Montfrans, GA, 2007)
"Bradykinin (BK) is a potent vasoactive peptide that may also participate in this model."1.31Intrarenal angiotensin and bradykinin peptide levels in the remnant kidney model of renal insufficiency. ( Campbell, DJ; Mackie, FE; Meyer, TW, 2001)
"Hyperkalemia is widely viewed as a common complication of ACE inhibition in azotemic patients."1.31Hyperkalemia, renal failure, and converting-enzyme inhibition: an overrated connection. ( Baigorria, ST; García, NH; Juncos, LI, 2001)
"Aminoglycoside nephrotoxicity remains a common clinical problem and is the major cause of acute toxic renal failure in hospitalized patients."1.29Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits. ( Amirault, P; Blanchet, F; Carbon, C; Heudes, D; Lortholary, O; Nochy, D; Seta, N, 1993)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's3 (11.11)18.2507
2000's12 (44.44)29.6817
2010's9 (33.33)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Serrano-Morillas, N1
González-Alayón, C1
Vastola-Mascolo, A1
Rodríguez-Rodríguez, AE1
Hernández, G1
Porrini, E1
Hernández-Guerra, M1
Alvarez de la Rosa, D1
Solà, E2
Solé, C1
Simón-Talero, M1
Martín-Llahí, M1
Castellote, J1
Garcia-Martínez, R1
Moreira, R1
Torrens, M1
Márquez, F1
Fabrellas, N1
de Prada, G1
Huelin, P1
Lopez Benaiges, E1
Ventura, M1
Manríquez, M1
Nazar, A2
Ariza, X1
Suñé, P1
Graupera, I1
Pose, E1
Colmenero, J1
Pavesi, M2
Guevara, M2
Navasa, M1
Xiol, X1
Córdoba, J1
Vargas, V1
Ginès, P2
Maruhashi, T1
Amioka, M1
Kishimoto, S1
Ikenaga, H1
Oki, K1
Ishida, M1
Kihara, Y1
Higashi, Y1
Ichikawa, D1
Kamijo-Ikemori, A1
Sugaya, T1
Shibagaki, Y1
Yasuda, T1
Hoshino, S1
Katayama, K1
Igarashi-Migitaka, J1
Hirata, K1
Kimura, K1
Lam, L1
Chiu, WW1
Davidson, JS1
Wesson, DE2
Simoni, J2
Hunter, JD1
Ravert, PK1
Lassetter, JH1
Williams, M1
Toshboltaeva, SS1
Murtazina, EP1
Terra, C1
Fernández, J1
Arroyo, V1
Jo, CH1
Epstein, M3
COPE, CL1
PEARSON, J1
TODD, RS1
LAINE, JB1
SINGH, LM1
VEGA, RE1
HEIDER, C1
HOWARD, JM1
van den Born, BJ1
Koopmans, RP1
van Montfrans, GA1
Nishiyama, A1
Kusaka, T1
Kitajima, H1
Lortholary, O1
Blanchet, F1
Nochy, D1
Heudes, D1
Seta, N1
Amirault, P1
Carbon, C1
Kudoh, A1
Sakai, T1
Ishihara, H1
Matsuki, A1
Deschênes, M1
Dufresne, MP1
Bui, B1
Fenyves, D1
Spahr, L1
Roy, L1
Lafortune, M1
Pomier-Layrargues, G1
Sorooshian, M1
Olson, JL1
Meyer, TW2
Bakris, GL1
Siomos, M1
Richardson, D1
Janssen, I1
Bolton, WK1
Hebert, L1
Agarwal, R1
Catanzaro, D1
Hostetter, TH2
Rosenberg, ME2
Ibrahim, HN2
Juknevicius, I2
Mackie, FE1
Campbell, DJ1
Mayan, H1
Kantor, R1
Farfel, Z1
García, NH1
Baigorria, ST1
Juncos, LI1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Midodrine and Albumin for Cirrhotic Patients in the Waiting List for Liver Transplantation[NCT00839358]Phase 4199 participants (Actual)Interventional2008-08-31Completed
Albumin Administration in the Prevention of Hepatorenal Syndrome and Death in Patients With Cirrhosis, Bacterial Infections Other Than Spontaneous Bacterial Peritonitis and High Risk of Hospital Mortality[NCT02034279]Phase 4136 participants (Actual)Interventional2014-05-31Terminated (stopped due to Low recruitment rate and expiration of the study drug)
Effects of Intravenous Albumin Administration on Renal Function and Survival in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis. A Prospective, Stratified, Randomized and Controlled Study.[NCT00124228]Phase 3110 participants (Actual)Interventional2004-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for aldosterone and Kidney Failure

ArticleYear
Renal protection in diabetes.
    Advance for NPs & PAs, 2011, Volume: 2, Issue:1

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Press

2011
Aldosterone receptor blockade and the role of eplerenone: evolving perspectives.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:10

    Topics: Aldosterone; Cardiovascular Diseases; Controlled Clinical Trials as Topic; Dose-Response Relationshi

2003
Aldosterone blockade: an emerging strategy for abrogating progressive renal disease.
    The American journal of medicine, 2006, Volume: 119, Issue:11

    Topics: Aldosterone; Algorithms; Disease Progression; Disease Susceptibility; Drug Labeling; Eplerenone; Fib

2006
[Role of aldosterone in oxidative stress and renal injury].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:9

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Eplerenone; Humans; Mineralocorticoid Receptor Antago

2007
Aldosterone in renal disease.
    Current opinion in nephrology and hypertension, 2001, Volume: 10, Issue:1

    Topics: Aldosterone; Animals; Hyperaldosteronism; Kidney Diseases; Renal Insufficiency

2001
Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift.
    Journal of hypertension, 2001, Volume: 19, Issue:5

    Topics: Aldosterone; Animals; Disease Progression; Humans; Hypertension; Kidney; Kidney Diseases; Renal Insu

2001
Aldosterone in progressive renal disease.
    Seminars in nephrology, 2001, Volume: 21, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hyperaldoste

2001

Trials

3 trials available for aldosterone and Kidney Failure

ArticleYear
Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial.
    Journal of hepatology, 2018, Volume: 69, Issue:6

    Topics: Adult; Aged; Albumins; Aldosterone; Ascites; Double-Blind Method; Female; Follow-Up Studies; Humans;

2018
Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study.
    Journal of hepatology, 2012, Volume: 57, Issue:4

    Topics: Adult; Aged; Albumins; Aldosterone; Anti-Bacterial Agents; Atrial Natriuretic Factor; Bacterial Infe

2012
Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study.
    Journal of hepatology, 2012, Volume: 57, Issue:4

    Topics: Adult; Aged; Albumins; Aldosterone; Anti-Bacterial Agents; Atrial Natriuretic Factor; Bacterial Infe

2012
Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study.
    Journal of hepatology, 2012, Volume: 57, Issue:4

    Topics: Adult; Aged; Albumins; Aldosterone; Anti-Bacterial Agents; Atrial Natriuretic Factor; Bacterial Infe

2012
Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study.
    Journal of hepatology, 2012, Volume: 57, Issue:4

    Topics: Adult; Aged; Albumins; Aldosterone; Anti-Bacterial Agents; Atrial Natriuretic Factor; Bacterial Infe

2012
ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group.
    Kidney international, 2000, Volume: 58, Issue:5

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cross-Over

2000

Other Studies

17 other studies available for aldosterone and Kidney Failure

ArticleYear
Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Aldosterone; Animals; Colon; Epithelial Sodium Channels; Gene Expression; Hypovolemia; Kidney; Liver

2023
Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency.
    Internal medicine (Tokyo, Japan), 2019, Nov-01, Volume: 58, Issue:21

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension, Mal

2019
Human liver-type fatty acid-binding protein protects against tubulointerstitial injury in aldosterone-induced renal injury.
    American journal of physiology. Renal physiology, 2015, Jan-15, Volume: 308, Issue:2

    Topics: Aldosterone; Angiotensinogen; Animals; Blood Pressure; Chemokine CCL2; Collagen Type I; Collagen Typ

2015
Overestimation of Aldosterone by Immunoassay in Renal Impairment.
    Clinical chemistry, 2016, Volume: 62, Issue:6

    Topics: Aldosterone; Humans; Immunoassay; Reference Standards; Renal Insufficiency

2016
Acid retention during kidney failure induces endothelin and aldosterone production which lead to progressive GFR decline, a situation ameliorated by alkali diet.
    Kidney international, 2010, Volume: 78, Issue:11

    Topics: Acid-Base Equilibrium; Acidosis; Administration, Oral; Aldosterone; Animals; Bicarbonates; Calcium G

2010
Role of serum renin and aldosterone in animal adaptation to high-altitude conditions.
    Bulletin of experimental biology and medicine, 2011, Volume: 150, Issue:5

    Topics: Adaptation, Physiological; Aldosterone; Altitude; Angiotensins; Animals; Atmospheric Pressure; Blood

2011
Angiotensin II receptors mediate increased distal nephron acidification caused by acid retention.
    Kidney international, 2012, Volume: 82, Issue:11

    Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Aldosterone; Angiotensin II; Angiotensin Receptor An

2012
ALDOSTERONE SECRETION IN SEVERE RENAL FAILURE.
    Clinical science, 1963, Volume: 25

    Topics: Acute Kidney Injury; Aldosterone; Blood; Feces; Humans; Kidney; Renal Insufficiency; Tritium; Urea;

1963
EFFECTS OF ALDOSTERONE ON PROLONGATION OF RENAL HOMOTRANSPLANTS IN DOGS.
    Surgery, gynecology & obstetrics, 1964, Volume: 119

    Topics: Acute Kidney Injury; Aldosterone; Blood Urea Nitrogen; Dogs; Kidney; Kidney Function Tests; Kidney T

1964
The renin-angiotensin system in malignant hypertension revisited: plasma renin activity, microangiopathic hemolysis, and renal failure in malignant hypertension.
    American journal of hypertension, 2007, Volume: 20, Issue:8

    Topics: Adult; Aldosterone; Biomarkers; Creatinine; Female; Follow-Up Studies; Hemolysis; Humans; Hypertensi

2007
Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9

    Topics: Aldosterone; Animals; Blood Gas Analysis; Diltiazem; Gases; Inulin; Kidney; Kidney Function Tests; K

1993
Renin-aldosterone in elderly patients with hyperkalaemia under anaesthesia.
    European journal of anaesthesiology, 1999, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Anesthesia, General; Anesthetics, Inhalation; An

1999
Predictors of clinical response to transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients with refractory ascites.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Ascites; Creatinine; Female; Follow-Up Studies; Humans;

1999
Effect of angiotensin II blockade on renal injury in mineralocorticoid-salt hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals

2000
Intrarenal angiotensin and bradykinin peptide levels in the remnant kidney model of renal insufficiency.
    Kidney international, 2001, Volume: 59, Issue:4

    Topics: Aldosterone; Angiotensinogen; Angiotensins; Animals; Bradykinin; Infarction; Ischemia; Kidney; Male;

2001
Trans-tubular potassium gradient in patients with drug-induced hyperkalemia.
    Nephron, 2001, Volume: 89, Issue:1

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Creatinin

2001
Hyperkalemia, renal failure, and converting-enzyme inhibition: an overrated connection.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; A

2001