Page last updated: 2024-11-07

aldosterone and Inappropriate ADH Syndrome

aldosterone has been researched along with Inappropriate ADH Syndrome in 30 studies

Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.

Research Excerpts

ExcerptRelevanceReference
"The present study was undertaken to determine whether urinary excretion of aquaporin-2 (AQP-2) participates in the involvement of arginine vasopressin (AVP) in hyponatremia less than 130 mmol/L in 33 elderly subjects (> or =65 yr old) during the last 5-yr period."7.71Close association of urinary excretion of aquaporin-2 with appropriate and inappropriate arginine vasopressin-dependent antidiuresis in hyponatremia in elderly subjects. ( Fukagawa, A; Higashiyama, M; Honda, K; Kusaka, I; Nagasaka, S; Nakamura, T; Saito, T, 2001)
"The present study was undertaken to determine whether urinary excretion of aquaporin-2 (AQP-2) participates in the involvement of arginine vasopressin (AVP) in hyponatremia less than 130 mmol/L in 33 elderly subjects (> or =65 yr old) during the last 5-yr period."3.71Close association of urinary excretion of aquaporin-2 with appropriate and inappropriate arginine vasopressin-dependent antidiuresis in hyponatremia in elderly subjects. ( Fukagawa, A; Higashiyama, M; Honda, K; Kusaka, I; Nagasaka, S; Nakamura, T; Saito, T, 2001)
"Patients with brain injury admitted to the intensive care unit were included and had their BNP, aldosterone and vasopressin levels dosed on day 7."1.35Hyponatremia and brain injury: absence of alterations of serum brain natriuretic peptide and vasopressin. ( Casulari, LA; Cosme, Sde L; Costa, KN; Cruz, LR; Miranda, LS; Nakamura, HM; Santos-Neto, RC, 2009)
"Aldosterone levels were much lower in ACTH deficiency patients during the hyponatremic state (33 +/- 40 pg/ml) when compared with the nonendocrine SIADH (120 +/- 60 pg/ml; P < 0."1.32Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency. ( Decaux, G; Musch, W; Penninckx, R; Soupart, A, 2003)
"Aldosterone levels were variable."1.31Hyponatremia in the postoperative craniofacial pediatric patient population: a connection to cerebral salt wasting syndrome and management of the disorder. ( Bradley, JP; Levine, JP; McCarthy, JG; Stelnicki, E; Weiner, HL, 2001)
"Special treatment for hyponatremia was not given in 30 of the 58 cases (control group)."1.28[Mechanism and therapy of hyponatremia with central origin]. ( Morinaga, K; Ohkawara, S; Tabuse, H, 1989)
"Because hyponatremia is frequently associated with preceding diuretic treatment and unrestricted fluid intake--conditions which have not been addressed sufficiently in published literature--we studied the pathophysiology and the clinical setting of such hyponatremia in a large group of internal medicine patients."1.27Role of diuretics, hormonal derangements, and clinical setting of hyponatremia in medical patients. ( Gross, P; Hackenthal, E; Hausmann, C; Ketteler, M; Rascher, W; Reinhard, C; Ritz, E; Schömig, A, 1988)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199014 (46.67)18.7374
1990's6 (20.00)18.2507
2000's9 (30.00)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Refardt, J1
Winzeler, B1
Meienberg, F1
Christ-Crain, M1
Bitew, S1
Imbriano, L1
Miyawaki, N1
Fishbane, S1
Maesaka, JK1
Costa, KN1
Nakamura, HM1
Cruz, LR1
Miranda, LS1
Santos-Neto, RC1
Cosme, Sde L1
Casulari, LA1
Wong, F1
Blei, AT1
Blendis, LM1
Thuluvath, PJ1
Caksen, H1
Cesur, Y1
Akgün, C1
Odabaş, D1
DALMAU-CIRIA, M1
Decaux, G2
Musch, W2
Penninckx, R1
Soupart, A1
Song, J1
Hu, X1
Khan, O1
Tian, Y1
Verbalis, JG1
Ecelbarger, CA1
Salomez-Granier, F1
Lefebvre, J1
Racadot, A1
Dewailly, D1
Linquette, M1
Johnston, ID1
Heymans, G1
Telerman, A1
Deconinck, I1
Brauman, H1
Shiigai, T2
Tomita, K2
Shichiri, M2
Andou, R2
Shinoda, T2
Takeuchi, J2
Mirsattari, SM1
Power, C1
Fine, A1
McGinn, GS1
Ludwick, S1
Canvin, JM1
Saito, T3
Fukagawa, A1
Higashiyama, M1
Nakamura, T1
Kusaka, I1
Nagasaka, S1
Honda, K1
Levine, JP1
Stelnicki, E1
Weiner, HL1
Bradley, JP1
McCarthy, JG1
Cooke, CR1
Turin, MD1
Walker, WG1
Farese, RV1
Karsh, SJ1
Bidot-López, P1
Whitaker, MD1
McArthur, RG1
Corenblum, B1
Davidman, M1
Haslam, RH1
Lolin, Y1
Jackowski, A1
Radetti, G1
Rizza, F1
Mengarda, G1
Pittschieler, K1
Eadington, DW1
Cowan, FM1
Liu, X1
Yura, T1
Takamitsu, Y1
Yuasa, S1
Miki, S1
Takahashi, N1
Bandai, H1
Sumikura, T1
Uchida, K1
Kiyomoto, H1
Matsuo, H1
Morinaga, K1
Tabuse, H1
Ohkawara, S1
Kaneko, K1
Okada, K1
Ishikawa, S1
Kuzuya, T1
Gross, P1
Ketteler, M1
Hausmann, C1
Reinhard, C1
Schömig, A1
Hackenthal, E1
Ritz, E1
Rascher, W1
Weise, K1
Zaritsky, A1
Leititis, JU1
Burghard, R1
Gordjani, N1
Kaethner, T1
Brandis, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987]122 participants (Actual)Observational2019-07-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aldosterone and Inappropriate ADH Syndrome

ArticleYear
Effects of changes in endocrine function on water and electrolyte metabolism.
    World journal of surgery, 1983, Volume: 7, Issue:5

    Topics: Addison Disease; Aldosterone; Endocrine Glands; Glomerular Filtration Rate; Humans; Hydrocortisone;

1983
Endocrine manifestations of critical illness in the child.
    Pediatric clinics of North America, 1987, Volume: 34, Issue:1

    Topics: Aldosterone; Catecholamines; Child; Diabetes Insipidus; Endocrine Glands; Glucagon; Glucocorticoids;

1987

Trials

1 trial available for aldosterone and Inappropriate ADH Syndrome

ArticleYear
A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: a multicenter, randomized, placebo-controlled trial.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:1

    Topics: Aldosterone; Antidiuretic Hormone Receptor Antagonists; Ascites; Azepines; Benzamides; Edema; Female

2003

Other Studies

27 other studies available for aldosterone and Inappropriate ADH Syndrome

ArticleYear
Artificial Syndrome of Inappropriate Antidiuresis Model as Potential Use for Diagnostic and Therapeutic Strategies.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:9

    Topics: Adult; Aldosterone; Female; Glycopeptides; Humans; Inappropriate ADH Syndrome; Male; Models, Biologi

2017
More on renal salt wasting without cerebral disease: response to saline infusion.
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:2

    Topics: Aged; Aged, 80 and over; Aldosterone; Biomarkers; Blood Volume; Diagnosis, Differential; Female; Hum

2009
Hyponatremia and brain injury: absence of alterations of serum brain natriuretic peptide and vasopressin.
    Arquivos de neuro-psiquiatria, 2009, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Brain Diseases, Metabolic; Brain Injuries; Female; Humans; Hyponatre

2009
Very high serum aldesterone level in an infant who expired.
    The Journal of emergency medicine, 2003, Volume: 24, Issue:4

    Topics: Aldosterone; Diarrhea; Emergency Treatment; Fatal Outcome; Gastroenteritis; Humans; Hyperaldosteroni

2003
[HYPERNATRIURIA AND HYPONATREMIA WITH NORMAL HYDRATION: SCHWARTZ-BARTTER SYNDROME].
    Medicina clinica, 1963, Volume: 41

    Topics: Aldosterone; Brain Neoplasms; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lung Neoplasms; Natr

1963
Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Aldosterone; Bicarbonates; Carbon Dioxide; Dia

2003
Increased blood pressure, aldosterone activity, and regional differences in renal ENaC protein during vasopressin escape.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Blood Pressure; Blotting, Western

2004
[Antidiuretic hormone levels (arginine-vasopressin) in cases of peripheral hypothyroidism. 26 cases].
    Presse medicale (Paris, France : 1983), 1983, Apr-09, Volume: 12, Issue:16

    Topics: Aged; Aldosterone; Arginine Vasopressin; Female; Humans; Hyponatremia; Hypothyroidism; Inappropriate

1983
[Ionic disorders associated with heparin therapy].
    Acta clinica Belgica, 1984, Volume: 39, Issue:4

    Topics: Aged; Aldosterone; Female; Heparin; Humans; Inappropriate ADH Syndrome; Water-Electrolyte Imbalance

1984
Increased urinary kallikrein-like activity in the syndrome of inappropriate secretion of antidiuretic hormone.
    Advances in experimental medicine and biology, 1983, Volume: 156 (Pt B)

    Topics: Aged; Aldosterone; Drinking; Female; Humans; Inappropriate ADH Syndrome; Kallikreins; Male; Middle A

1983
Increased urinary kallikrein-like activity in the syndrome of inappropriate secretion of antidiuretic hormone.
    Nephron, 1983, Volume: 35, Issue:1

    Topics: Aged; Aldosterone; Female; Humans; Inappropriate ADH Syndrome; Kallikreins; Kinins; Male; Middle Age

1983
Neuropsychiatric systemic lupus erythematosus and the syndrome of inappropriate secretion of antidiuretic hormone: a case report with very late onset systemic lupus erythematosus.
    British journal of rheumatology, 1998, Volume: 37, Issue:10

    Topics: Aged; Aged, 80 and over; Aldosterone; Antibodies, Antinuclear; Brain; Complement C3; Complement C4;

1998
Close association of urinary excretion of aquaporin-2 with appropriate and inappropriate arginine vasopressin-dependent antidiuresis in hyponatremia in elderly subjects.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:4

    Topics: Aged; Aging; Aldosterone; Aquaporin 2; Aquaporin 6; Aquaporins; Arginine Vasopressin; Blood Volume;

2001
Utility and limitations of biochemical parameters in the evaluation of hyponatremia in the elderly.
    International urology and nephrology, 2001, Volume: 32, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Isot

2001
Hyponatremia in the postoperative craniofacial pediatric patient population: a connection to cerebral salt wasting syndrome and management of the disorder.
    Plastic and reconstructive surgery, 2001, Volume: 108, Issue:6

    Topics: Aldosterone; Atrial Natriuretic Factor; Child, Preschool; Craniosynostoses; Electrolytes; Female; Hu

2001
The syndrome of inappropriate antidiuretic hormone secretion (SIADH): pathophysiologic mechanisms in solute and volume regulation.
    Medicine, 1979, Volume: 58, Issue:3

    Topics: Adult; Aged; Aldosterone; Body Weight; Drinking; Female; Humans; Inappropriate ADH Syndrome; Kidney

1979
Acute intermittent porphyria associated with inappropriate antidiuretic hormone secretion, hypokalemic alkalosis, and secondary hyperaldosteronism.
    Southern medical journal, 1979, Volume: 72, Issue:9

    Topics: Acute Disease; Adult; Aldosterone; Alkalosis; Blood Urea Nitrogen; Female; Humans; Hyperaldosteronis

1979
Idiopathic, sustained, inappropriate secretion of ADH with associated hypertension and thirst.
    The American journal of medicine, 1979, Volume: 67, Issue:3

    Topics: Adolescent; Aldosterone; Diet; Drinking; Female; Humans; Hypertension; Inappropriate ADH Syndrome; O

1979
Hyponatraemia in neurosurgical patients: diagnosis using derived parameters of sodium and water homeostasis.
    British journal of neurosurgery, 1992, Volume: 6, Issue:5

    Topics: Aged; Aldosterone; Brain Diseases; Female; Homeostasis; Humans; Hyponatremia; Inappropriate ADH Synd

1992
Adipsic hypernatremia in two sisters.
    American journal of diseases of children (1960), 1991, Volume: 145, Issue:3

    Topics: Aldosterone; Blood Urea Nitrogen; Female; Humans; Hypernatremia; Hypothalamus; Inappropriate ADH Syn

1991
Dissociation between the secretion and renal action of endogenous atrial natriuretic peptide in the syndrome of inappropriate antidiuresis.
    Postgraduate medical journal, 1990, Volume: 66, Issue:771

    Topics: Aged; Aldosterone; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Volume; Female; Humans; In

1990
[Study on the metabolic changes of hormones regulating water and electrolytes before and after acute water loading in myxedematous patients].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1990, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Arginine Vasopressin; Atrial Natriuretic Factor; Female; Humans; Ina

1990
[Hyponatremia in isolated deficiency of adrenocorticotropic hormone: role of a decrease in aldosterone secretion independent of antidiuretic hormone excess].
    Nihon Jinzo Gakkai shi, 1990, Volume: 32, Issue:7

    Topics: Adrenocorticotropic Hormone; Aldosterone; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

1990
[Mechanism and therapy of hyponatremia with central origin].
    No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:6

    Topics: Aldosterone; Cerebrovascular Disorders; Craniocerebral Trauma; Glucose; Humans; Hydrocortisone; Hypo

1989
Role of atrial natriuretic peptide in natriuresis in volume-expanded rats.
    The American journal of physiology, 1987, Volume: 253, Issue:6 Pt 2

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Volume; Glomerular Filtration Rate; Inappropr

1987
Role of diuretics, hormonal derangements, and clinical setting of hyponatremia in medical patients.
    Klinische Wochenschrift, 1988, Aug-01, Volume: 66, Issue:15

    Topics: Aldosterone; Arginine Vasopressin; Diuretics; Electrolytes; Epinephrine; Furosemide; Heart Failure;

1988
[Developmental physiologic aspects of volume and sodium regulation in premature and mature newborn infants].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1987, Volume: 135, Issue:1

    Topics: Aldosterone; Birth Weight; Blood Volume; Gestational Age; Glomerular Filtration Rate; Humans; Inappr

1987