Page last updated: 2024-11-07

aldosterone and Hypovolemia

aldosterone has been researched along with Hypovolemia in 19 studies

Hypovolemia: An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).

Research Excerpts

ExcerptRelevanceReference
"Fifty patients with cirrhosis and tense refractory ascites were randomly assigned to be treated with either midodrine (n=25) (12."5.19Comparison of midodrine and albumin in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients: a randomized pilot study. ( ElBaz, AA; Hamdy, H; Hassan, A; Hassanin, O, 2014)
"Twenty-four patients with cirrhosis and ascites were randomly assigned to be treated with either midodrine (n=11) (12."5.13Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study. ( Appenrodt, B; Grünhage, F; Heller, J; Lammert, F; Rabe, C; Sauerbruch, T; Schepke, M; Trebicka, J; Wolf, A, 2008)
"Following dehydration, 2% of the fluid lost was replaced during the first 45 min of a 100-min rest period by one of three random Rehy treatments (0."2.73Rehydration with fluid of varying tonicities: effects on fluid regulatory hormones and exercise performance in the heat. ( Armstrong, LE; Castellani, JW; Echegaray, ME; Kenefick, RW; Maresh, CM; Riebe, D, 2007)
"Liver cirrhosis is associated to circulatory abnormalities leading to hypovolemia and stimulation of the renin-angiotensin-aldosterone system (RAAS)."1.91Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression. ( Alvarez de la Rosa, D; González-Alayón, C; Hernández, G; Hernández-Guerra, M; Porrini, E; Rodríguez-Rodríguez, AE; Serrano-Morillas, N; Vastola-Mascolo, A, 2023)
"Aldosterone was higher before than after fluid resuscitation in foals, and was higher in foals both before and after fluid resuscitation than in mature horses."1.35Plasma aldosterone, vasopressin and atrial natriuretic peptide in hypovolaemia: a preliminary comparative study of neonatal and mature horses. ( Boston, RC; Corley, KT; Hollis, AR, 2008)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's0 (0.00)18.2507
2000's10 (52.63)29.6817
2010's6 (31.58)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Serrano-Morillas, N1
González-Alayón, C1
Vastola-Mascolo, A1
Rodríguez-Rodríguez, AE1
Hernández, G1
Porrini, E1
Hernández-Guerra, M1
Alvarez de la Rosa, D1
Seeley, MC1
Thynne, TR1
Braund, WJ1
Worthley, DL1
Gallagher, C1
Sanders, P1
Lau, DH1
Pathare, G1
Anderegg, M1
Albano, G1
Lang, F1
Fuster, DG1
Hamdy, H1
ElBaz, AA1
Hassan, A1
Hassanin, O1
Thornton, SN1
Ropars, A1
Hoover, RS1
Samavat, S1
Ahmadpoor, P1
Samadian, F1
van der Lubbe, N1
Zietse, R1
Hoorn, EJ1
Andersen, RF1
Nørgaard, H1
Hagstrøm, S1
Bjerre, J1
Jespersen, B1
Rittig, S1
Donckerwolcke, RA1
France, A1
Raes, A1
Vande Walle, J1
FINE, D1
MEISELAS, LE1
AUERBACH, T1
White, PC1
Raj, SR1
Biaggioni, I1
Yamhure, PC1
Black, BK1
Paranjape, SY1
Byrne, DW1
Robertson, D1
Stewart, JM1
Glover, JL1
Medow, MS1
Kenefick, RW1
Maresh, CM1
Armstrong, LE1
Riebe, D1
Echegaray, ME1
Castellani, JW1
Markel, AL1
Redina, OE1
Gilinsky, MA1
Dymshits, GM1
Kalashnikova, EV1
Khvorostova, YV1
Fedoseeva, LA1
Jacobson, GS1
Hollis, AR1
Boston, RC1
Corley, KT1
Appenrodt, B1
Wolf, A1
Grünhage, F1
Trebicka, J1
Schepke, M1
Rabe, C1
Lammert, F1
Sauerbruch, T1
Heller, J1
Simma, B1
Burger, R1
Falk, M1
Sacher, P1
Torresani, T1
Fanconi, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Saline on Exercise Tolerance in Orthostatic Intolerance[NCT01000350]40 participants (Anticipated)Interventional2009-10-31Active, not recruiting
Efficacy of Terlipressin in Cirrhotic Patients With Recidivation Ascites Treated With Paracentesis and Albumin. A Multi-center Randomized Controlled Study[NCT00986817]Phase 382 participants (Actual)Interventional2009-11-30Completed
Vasoconstrictors as Alternatives to Albumin After Large Volume Paracentesis in Cirrhosis[NCT00108355]Phase 429 participants (Actual)Interventional2003-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Development of Post-paracentesis Circulatory Dysfunction (PCD)

Defined as an increase in Plasma Renin Activity (PRA) by >50% from baseline to a level > 4 ng/mL/h at post-paracentesis day (NCT00108355)
Timeframe: 6 days after paracentesis

Interventionparticipants (Number)
Albumin (Control Group)2
Vasoconstrictor (Treatment Group)2

Time to Recurrence of Ascites.

Comparison between Albumin (Control group) and Vasoconstrictor (Treatment group) (NCT00108355)
Timeframe: Variable depending on the patient, average 10 days

Interventiondays (Median)
Albumin (Control Group)10
Vasoconstrictor (Treatment Group)8

Reviews

3 reviews available for aldosterone and Hypovolemia

ArticleYear
Aldosterone, hypertension, and beyond.
    Iranian journal of kidney diseases, 2011, Volume: 5, Issue:2

    Topics: Aldosterone; Epigenomics; Epithelial Sodium Channels; Humans; Hyperaldosteronism; Hypertension; Hypo

2011
Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron.
    Current opinion in nephrology and hypertension, 2013, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Epithelial Sodium Channels; Humans; Hyperkalemia; Hypertension

2013
Aldosterone synthase deficiency and related disorders.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Cortisone; Cytochrome P-450 CYP11B2; Exons; Humans; Hy

2004

Trials

4 trials available for aldosterone and Hypovolemia

ArticleYear
Comparison of midodrine and albumin in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients: a randomized pilot study.
    Journal of clinical gastroenterology, 2014, Volume: 48, Issue:2

    Topics: Albumins; Aldosterone; Ascites; Creatinine; Female; Humans; Hypovolemia; Liver Cirrhosis; Male; Midd

2014
Rehydration with fluid of varying tonicities: effects on fluid regulatory hormones and exercise performance in the heat.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:5

    Topics: Administration, Oral; Adult; Aldosterone; Arginine Vasopressin; Body Temperature Regulation; Dehydra

2007
Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Adrenergic alpha-Agonists; Albumins; Aldosterone; Ascites; Double-Blind Method; Female; Humans; Hypo

2008
Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Adrenergic alpha-Agonists; Albumins; Aldosterone; Ascites; Double-Blind Method; Female; Humans; Hypo

2008
Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Adrenergic alpha-Agonists; Albumins; Aldosterone; Ascites; Double-Blind Method; Female; Humans; Hypo

2008
Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Adrenergic alpha-Agonists; Albumins; Aldosterone; Ascites; Double-Blind Method; Female; Humans; Hypo

2008
The release of antidiuretic hormone is appropriate in response to hypovolemia and/or sodium administration in children with severe head injury: a trial of lactated Ringer's solution versus hypertonic saline.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:3

    Topics: Adolescent; Aldosterone; Child; Child, Preschool; Craniocerebral Trauma; Humans; Hypovolemia; Infant

2001

Other Studies

12 other studies available for aldosterone and Hypovolemia

ArticleYear
Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Aldosterone; Animals; Colon; Epithelial Sodium Channels; Gene Expression; Hypovolemia; Kidney; Liver

2023
Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria.
    The American journal of medicine, 2021, Volume: 134, Issue:9

    Topics: Aldosterone; Antidiuretic Agents; Deamino Arginine Vasopressin; Diabetes Insipidus, Neurogenic; Fema

2021
Elevated FGF23 Levels in Mice Lacking the Thiazide-Sensitive NaCl cotransporter (NCC).
    Scientific reports, 2018, 02-26, Volume: 8, Issue:1

    Topics: Aldosterone; Analysis of Variance; Animals; Calcium; Disease Models, Animal; Eplerenone; Femur; Fibr

2018
Hypovolaemia-induced metabolic dysfunction, mediated in part by aldosterone and angiotensin.
    Journal of hypertension, 2009, Volume: 27, Issue:10

    Topics: Aldosterone; Angiotensins; Humans; Hypertension; Hypovolemia; Metabolic Syndrome; Renin-Angiotensin

2009
Angiotensin II: a candidate for an aldosterone-independent mediator of potassium preservation during volume depletion.
    Kidney international, 2011, Volume: 79, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; CSK Tyrosine-Protein Kinase; Diet, Sodium-Restricted; Humans;

2011
High plasma aldosterone is associated with a risk of reversible decreased eGFR in childhood idiopathic nephrotic syndrome.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:4

    Topics: Adolescent; Albuminuria; Aldosterone; Blood Volume; Child; Child, Preschool; Echocardiography; Femal

2013
Distal nephron sodium-potassium exchange in children with nephrotic syndrome.
    Clinical nephrology, 2003, Volume: 59, Issue:4

    Topics: Adolescent; Aldosterone; Child; Child, Preschool; Humans; Hypovolemia; Infant; Nephrons; Nephrotic S

2003
The effect of acute hypovolemia on the release of aldosterone and on the renal excretion of sodium.
    The Journal of clinical investigation, 1958, Volume: 37, Issue:2

    Topics: Aldosterone; Blood Volume; Body Fluids; Humans; Hypovolemia; Kidney; Renal Elimination; Sodium; Sodi

1958
Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome.
    Circulation, 2005, Apr-05, Volume: 111, Issue:13

    Topics: Adult; Aldosterone; Blood Volume; Case-Control Studies; Erythropoietin; Female; Hemodynamics; Humans

2005
Increased plasma angiotensin II in postural tachycardia syndrome (POTS) is related to reduced blood flow and blood volume.
    Clinical science (London, England : 1979), 2006, Volume: 110, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Analysis of Variance; Angiotensin II; Blood Volume; Case-Control Stu

2006
Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension.
    The Journal of endocrinology, 2007, Volume: 195, Issue:3

    Topics: Adrenal Cortex; Adrenal Medulla; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure;

2007
Plasma aldosterone, vasopressin and atrial natriuretic peptide in hypovolaemia: a preliminary comparative study of neonatal and mature horses.
    Equine veterinary journal, 2008, Volume: 40, Issue:1

    Topics: Aging; Aldosterone; Animals; Animals, Newborn; Atrial Natriuretic Factor; Body Fluids; Female; Fluid

2008