Page last updated: 2024-11-07

aldosterone and Hyperglycemia, Postprandial

aldosterone has been researched along with Hyperglycemia, Postprandial in 37 studies

Hyperglycemia, Postprandial: Abnormally high BLOOD GLUCOSE level after a meal.

Research Excerpts

ExcerptRelevanceReference
"The diagnosis of gestational diabetes mellitus (GDM) and impaired glucose tolerance during pregnancy were made according to the guidelines of the Chinese Society of Obstetrics."5.38Renin angiotensin aldosterone system and glycemia in pregnancy. ( Chen, GJ; Chen, YP; Gong, J; Hocher, B; Li, J; Pfab, T; Reichetzeder, C; Wang, ZN; Xiao, XM; Xu, H, 2012)
"Type 1 diabetes was induced in female Wistar rats by a single tail vein injection of streptozotocin (STZ), and SPL was administrated daily by gavage, from days 3-21."1.46Aldosterone signaling regulates the over-expression of claudin-4 and -8 at the distal nephron from type 1 diabetic rats. ( González-Ramírez, R; Molina-Jijón, E; Namorado-Tónix, C; Pedraza-Chaverri, J; Reyes, JL; Rodríguez-Muñoz, R, 2017)
"Dapagliflozin treatment showed beneficial effects on diabetic nephropathy, which might be via suppression of renal RAS component expression, oxidative stress and interstitial fibrosis in OLETF rats."1.43Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes. ( Ahn, YB; Chung, S; Kim, ES; Kim, JW; Kim, MJ; Kim, SJ; Ko, SH; Lee, EM; Moon, SD; Shin, SJ; Yoo, YH, 2016)
"Aldosterone plays a crucial role in cardiovascular disease."1.39Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity. ( Berger, S; Lohmann, C; Lüscher, TF; Matter, CM; Miranda, MX; Nussberger, J; Ruschitzka, F; Schäfer, N; van Tits, LJ; Vergopoulos, A; Verrey, F; Winnik, S, 2013)
"Patients with type 1 diabetes mellitus (DM) and renal hyperfiltration also exhibit systemic microvascular abnormalities, including endothelial dysfunction."1.39Renal hyperfiltration and systemic blood pressure in patients with uncomplicated type 1 diabetes mellitus. ( Cherney, DZ; Maahs, DM; Perkins, BA; Yang, GK, 2013)
"The diagnosis of gestational diabetes mellitus (GDM) and impaired glucose tolerance during pregnancy were made according to the guidelines of the Chinese Society of Obstetrics."1.38Renin angiotensin aldosterone system and glycemia in pregnancy. ( Chen, GJ; Chen, YP; Gong, J; Hocher, B; Li, J; Pfab, T; Reichetzeder, C; Wang, ZN; Xiao, XM; Xu, H, 2012)
"Thus, in insulin-resistant type 2 diabetes (T2D), oxidative stress generated by hyperglycemia and aldosterone would potentiate the oxidative destruction of tissue and important regulators of glucose metabolism like adiponectin and insulin."1.35The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways. ( Jadhav, A; Lane, N; Ndisang, JF, 2009)
"Aldosterone was reduced after the glucose load in all subjects studied, falling to 73% of basal at 60 min in diabetics (p less than 0."1.26Effect of acute hyperglycaemia on plasma potassium and aldosterone levels in type 2 (non-insulin-dependent) diabetes. ( Brajkovich, IE; Joplin, GF; Loizou, SA; Mashiter, K; Rosenstock, J, 1982)
"In thirteen patients with ketoacidosis, mean plasma renin activity (PRA) was 58 plus or minus 12 (S."1.25Plasma renin activity and blood volume in uncontrolled diabetes. Ketoacidosis, a state of secondary aldosteronism. ( Assal, JP; Christlieb, AR; Katsilambros, N; Kozak, GP; Suzuki, T; Williams, GH, 1975)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199017 (45.95)18.7374
1990's3 (8.11)18.2507
2000's4 (10.81)29.6817
2010's12 (32.43)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Gromotowicz-Poplawska, A1
Szoka, P1
Zakrzeska, A1
Kolodziejczyk, P1
Marcinczyk, N1
Szemraj, J1
Tutka, P1
Chabielska, E1
Molina-Jijón, E1
Rodríguez-Muñoz, R1
González-Ramírez, R1
Namorado-Tónix, C1
Pedraza-Chaverri, J1
Reyes, JL1
Takashi, Y1
Koga, M1
Matsuzawa, Y1
Saito, J1
Omura, M1
Nishikawa, T1
Schäfer, N1
Lohmann, C1
Winnik, S1
van Tits, LJ1
Miranda, MX1
Vergopoulos, A1
Ruschitzka, F1
Nussberger, J1
Berger, S1
Lüscher, TF1
Verrey, F1
Matter, CM1
Yang, GK1
Maahs, DM1
Perkins, BA1
Cherney, DZ1
Luther, JM2
Byrne, LM1
Yu, C1
Wang, TJ1
Brown, NJ1
Shin, SJ1
Chung, S1
Kim, SJ1
Lee, EM1
Yoo, YH1
Kim, JW1
Ahn, YB1
Kim, ES1
Moon, SD1
Kim, MJ1
Ko, SH1
Ndisang, JF1
Lane, N1
Jadhav, A1
Lian, M1
Hewitson, TD1
Wigg, B1
Samuel, CS1
Chow, F1
Becker, GJ1
Chen, YP1
Li, J1
Wang, ZN1
Reichetzeder, C1
Xu, H1
Gong, J1
Chen, GJ1
Pfab, T1
Xiao, XM1
Hocher, B1
Kuo, FC1
Hung, YJ1
Hsieh, CH1
Hsiao, FC1
Saha, S1
Schwarz, PE1
Bergmann, S1
Bornstein, SR1
Graessler, J1
Kopprasch, S1
Fouad, AA1
Al-Mulhim, AS1
Jresat, I1
Morsy, MA1
Luo, P1
Dematteo, A1
Wang, Z1
Zhu, L1
Wang, A1
Kim, HS1
Pozzi, A1
Stafford, JM1
Weekers, L1
Bouhanick, B1
Hadjadj, S1
Gallois, Y1
Roussel, R1
Pean, F1
Ankotche, A1
Chatellier, G1
Alhenc-Gelas, F1
Lefebvre, PJ1
Marre, M1
King, AJ1
Olivier, NB1
Mohankumar, PS1
Lee, JS1
Padmanabhan, V1
Fink, GD1
Nützi, D1
Beretta-Piccoli, C1
Ferrier, CP1
Link, L1
Gerber, A1
Weidmann, P1
Hochberg, Z1
Dickerman, Z1
Kaufman, H1
Laron, Z1
Sunderlin, FS1
Anderson, GH1
Streeten, DH1
Blumenthal, SA1
Hughes, IA1
Davies, PA1
Rosenstock, J1
Loizou, SA1
Brajkovich, IE1
Mashiter, K1
Joplin, GF1
Levine, DZ1
Iacovitti, M1
Burns, KD1
Waldhäusl, W1
Kleinberger, G1
Korn, A1
Dudczak, R1
Bratusch-Marrain, P1
Nowotny, P1
Belov, VA1
Vasil'ev, VI1
Gerasimov, GM1
Vishnevskaia, IG1
Blichert-Toft, M1
Christensen, V1
Engquist, A1
Fog-Moller, F1
Kehlet, H1
Madsen, SN1
Skovsted, L1
Thode, J1
Olgaard, K1
Goldfarb, S2
Cox, M1
Singer, I2
Goldberg, M2
Christlieb, AR1
Assal, JP1
Katsilambros, N1
Williams, GH1
Kozak, GP1
Suzuki, T1
Strunk, B1
Ilieva, G1
Tolekova, A1
Logofetov, A1
Andreis, PG1
Mazzocchi, G1
Cavallini, L1
Rebuffat, P1
Nussdorfer, GG1
Appiani, AC1
Assael, BM1
Tirelli, AS1
Cavanna, G1
Marra, G1
West, ML1
Magner, PO1
Richardson, RM1
Halperin, ML1
Serebrovskaia, IuA1
Kiseleva, ZM1
Speranskaia, NV1
Spivak, GL1
Paleeva, FM1
Hori, S2
Masumura, S2
Ono, K2
Sato, Y1
Thistlethwaite, D1
Darling, JA1
Fraser, R1
Rees, LH1
Harkness, RA1
Kolanowski, J1
Pizarro, MA1
De Gasparo, M1
Desmecht, P1
Harvengt, C1
Crabbé, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aldosterone and Glucose Homeostasis[NCT00732160]34 participants (Actual)Interventional2008-09-30Completed
Assessment of the Renin-angiotensin-aldosterone System (RAAS) and Antidiuretic Function in Patients With Type 2 Diabetes Before and During Treatment With Sodium-glucose Co-transporter 2 Inhibitors (SGLT2i): the GliRACo 1 Study[NCT03917758]30 participants (Anticipated)Interventional2018-10-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Insulin Secretion

Acute Insulin response during Hyperglycemic clamp (delta insulin uU/mL, t=0-10) (NCT00732160)
Timeframe: 3 hours

InterventionuU/mL (Mean)
Vehicle, HS48.9
Vehicle, LS37.6
Aldosterone, HS51.8
Aldosterone, LS34.4

Insulin Sensitivity

Insulin sensitivity index (ISI) was calculated by dividing the average glucose infusion rate (mg glucose infusion/kg body weight/min) by the average insulin concentration (uU/mL) from 90 to 120 minutes. This was multiplied by 100 (thus, x100 in units description), per reporting convention in literature. (NCT00732160)
Timeframe: 3 hours

Interventionmg/kg/min per uU/mL*100 (Mean)
Vehicle, HS25.2
Vehicle, LS24.8
Aldosterone, HS23.4
Aldosterone, LS24.7

Reviews

1 review available for aldosterone and Hyperglycemia, Postprandial

ArticleYear
Neonatal endocrine and metabolic emergencies.
    Clinics in endocrinology and metabolism, 1980, Volume: 9, Issue:3

    Topics: Adrenal Insufficiency; Aldosterone; Disorders of Sex Development; Emergencies; Female; Humans; Hyper

1980

Trials

3 trials available for aldosterone and Hyperglycemia, Postprandial

ArticleYear
Dietary sodium restriction decreases insulin secretion without affecting insulin sensitivity in humans.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:10

    Topics: Adult; Aldosterone; Blood Glucose; Cross-Over Studies; Diet, Sodium-Restricted; Double-Blind Method;

2014
Circulating very-low-density lipoprotein from subjects with impaired glucose tolerance accelerates adrenocortical cortisol and aldosterone synthesis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2013, Volume: 45, Issue:2

    Topics: Adrenal Cortex; Aged; Aldosterone; Cell Line; Glucose Intolerance; Glycated Hemoglobin; Humans; Hydr

2013
Acute hyperkalemia induced by hyperglycemia: hormonal mechanisms.
    Annals of internal medicine, 1976, Volume: 84, Issue:4

    Topics: Acute Disease; Adrenal Cortex Function Tests; Adult; Aldosterone; Clinical Trials as Topic; Desoxyco

1976

Other Studies

33 other studies available for aldosterone and Hyperglycemia, Postprandial

ArticleYear
Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model.
    Cells, 2021, 02-22, Volume: 10, Issue:2

    Topics: Aldosterone; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyperglycemia; Rats;

2021
Aldosterone signaling regulates the over-expression of claudin-4 and -8 at the distal nephron from type 1 diabetic rats.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Aldosterone; Animals; Claudin-4; Claudins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type

2017
Circulating pentraxin 3 is positively associated with chronic hyperglycemia but negatively associated with plasma aldosterone concentration.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Aldosterone; Biomarkers; C-Reactive Protein; Chronic Disease; Female; Humans; Hyperglycemia; Male; M

2018
Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity.
    European heart journal, 2013, Volume: 34, Issue:45

    Topics: Adipose Tissue; Aldosterone; Animals; Antioxidants; Aorta; Cyclooxygenase 1; Cyclooxygenase Inhibito

2013
Renal hyperfiltration and systemic blood pressure in patients with uncomplicated type 1 diabetes mellitus.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Diabetes Melli

2013
Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Aldosterone; Animals; Benzhydryl Compounds; Chymosin; Diabetes Mellitus, Type 2; Diabetic Nephropath

2016
The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways.
    Endocrinology, 2009, Volume: 150, Issue:5

    Topics: Aldosterone; Animals; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug E

2009
Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Blotting, Western; Collagen Type IV; Diabetes Mellitus, Experi

2012
Renin angiotensin aldosterone system and glycemia in pregnancy.
    Clinical laboratory, 2012, Volume: 58, Issue:5-6

    Topics: Adult; Aldosterone; Blood Glucose; Diabetes, Gestational; Female; Glucose Tolerance Test; Humans; Hy

2012
An occult aldosterone-producing adenoma initially presenting as hyperosmolar hyperglycaemic state.
    Annals of clinical biochemistry, 2012, Volume: 49, Issue:Pt 5

    Topics: Adenoma; Aldosterone; Diabetes Complications; Humans; Hyperglycemia; Male; Middle Aged

2012
Protective effects of captopril in diabetic rats exposed to ischemia/reperfusion renal injury.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Caspase 3; Creatinine; Di

2013
Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.
    Diabetologia, 2013, Volume: 56, Issue:4

    Topics: Adipocytes; Adiponectin; Adipose Tissue; Aldosterone; Animals; Blood Glucose; Body Composition; Cons

2013
Modulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients.
    Diabetes, 2005, Volume: 54, Issue:10

    Topics: Adult; Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes

2005
Hypertension caused by prenatal testosterone excess in female sheep.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Chlorides; Cholesterol; Disease Models, Animal; Dyslipidemias;

2007
Studies on acute glucose-induced aldosterone suppression: role of renin-angiotensin system.
    Klinische Wochenschrift, 1984, Mar-01, Volume: 62, Issue:5

    Topics: Adult; Aldosterone; Blood Glucose; Captopril; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperg

1984
Evaluation of the renin-aldosterone system during hypo- and hyperglycemia in children and adolescents.
    Hormone research, 1980, Volume: 12, Issue:1

    Topics: Adolescent; Aldosterone; Child; Female; Glucose; Humans; Hyperglycemia; Hypoglycemia; Insulin; Male;

1980
The renin-angiotensin-aldosterone system in diabetic patients with hyperkalemia.
    Diabetes, 1981, Volume: 30, Issue:4

    Topics: Adult; Aged; Aldosterone; Diabetes Complications; Female; Fludrocortisone; Humans; Hyperglycemia; Hy

1981
Effect of acute hyperglycaemia on plasma potassium and aldosterone levels in type 2 (non-insulin-dependent) diabetes.
    Diabetologia, 1982, Volume: 22, Issue:3

    Topics: Aldosterone; Blood Glucose; Desoxycorticosterone; Diabetes Mellitus; Glucose Tolerance Test; Homeost

1982
Distal tubule bicarbonate reabsorption in intact and remnant diabetic kidneys.
    Kidney international, 2000, Volume: 57, Issue:2

    Topics: Absorption; Acid-Base Equilibrium; Acidosis; Aldosterone; Animals; Bicarbonates; Biological Transpor

2000
Severe hyperglycemia: effects of rehydration on endocrine derangements and blood glucose concentration.
    Diabetes, 1979, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Glucose; C-Peptide; Dehydration; Diabetic Ketoacidosis;

1979
[Renin activity and functional status of the adrenal cortex in surgical intervention during ketamine anesthesia].
    Vestnik khirurgii imeni I. I. Grekova, 1979, Volume: 122, Issue:2

    Topics: 11-Hydroxycorticosteroids; Adolescent; Adrenal Cortex; Adrenal Cortex Hormones; Adult; Aged; Aldoste

1979
Influence of age on the endocrine-metabolic response to surgery.
    Annals of surgery, 1979, Volume: 190, Issue:6

    Topics: Adult; Age Factors; Aged; Aldosterone; Anesthesia, General; Electrolytes; Endocrine Glands; Hernia,

1979
Plasma renin activity and blood volume in uncontrolled diabetes. Ketoacidosis, a state of secondary aldosteronism.
    Diabetes, 1975, Volume: 24, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Blood Glucose; Blood Volume; Diabetic Ketoacidosis; Female; Huma

1975
Paradoxical glucose-induced hyperkalemia. Combined aldosterone-insulin deficiency.
    The American journal of medicine, 1975, Volume: 59, Issue:5

    Topics: Aldosterone; Desoxycorticosterone; Diabetes Complications; Diabetes Mellitus; Humans; Hyperglycemia;

1975
Plasma aldosterone concentration during hypoxia, stimulated hyperglycaemia and when protein synthesis is blocked with actinomycin D.
    Acta physiologica et pharmacologica Bulgarica, 1990, Volume: 16, Issue:4

    Topics: Aldosterone; Animals; Blood Glucose; Dactinomycin; Hyperglycemia; Hypoxia; Indicators and Reagents;

1990
Morphology and functional responses of isolated zona glomerulosa cells of streptozotocin-induced diabetic rats.
    Experimental pathology, 1990, Volume: 39, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Diabetes Mellitus

1990
Sodium excretion and hyperfiltration during glucose infusion in man.
    American journal of nephrology, 1990, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Blood Glucose; Blood Volume; Female; Glomerular Filtration Rate; Glu

1990
A renal mechanism limiting the degree of potassium loss in severely hyperglycemic patients.
    American journal of nephrology, 1988, Volume: 8, Issue:5

    Topics: Aldosterone; Diabetic Ketoacidosis; Humans; Hyperglycemia; Hyperglycemic Hyperosmolar Nonketotic Com

1988
[Renin activity in the blood plasma in pheochromocytoma].
    Kardiologiia, 1973, Volume: 13, Issue:4

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Cardiomegaly; Catecholamines; Chromatograph

1973
Effect of aldosterone on angiotensin-induced glycosuria.
    Mie medical journal, 1969, Volume: 19, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Glycosuria; Hyperglycemia; Injections, Intravenous; Rabbits; R

1969
Mechanism of angiotensin-induce glycosuria.
    Mie medical journal, 1969, Volume: 19, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Blood Glucose; Epinephrine; Glycosuria; Hyperglycemia; Injecti

1969
Proceedings: Familial glucocorticoid deficiency.
    The Journal of endocrinology, 1974, Volume: 63, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Corticosterone; Cortison

1974
Influence of fasting on adrenocortical and pancreatic islet response to glucose loads in the obese.
    European journal of clinical investigation, 1970, Volume: 1, Issue:1

    Topics: Acidosis, Renal Tubular; Adrenal Glands; Adult; Aldosterone; Bicarbonates; Body Weight; Fasting; Fat

1970