aldosterone has been researched along with Hepatorenal Syndrome in 9 studies
Hepatorenal Syndrome: Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Midodrine and octreotide were dosed to obtain a stable increase of at least 15 mm Hg of mean arterial pressure." | 6.69 | Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide. ( Amodio, P; Angeli, P; Caregaro, L; Craighero, R; Gatta, A; Gerunda, G; Maffei-Faccioli, A; Merenda, R; Roner, P; Sticca, A; Volpin, R, 1999) |
| "The adrenergic agonist midodrine improved circulatory and renal dysfunction when acutely administered in nonazotemic cirrhotic patients with ascites while its combination with octreotide has recently been proposed as an effective treatment of type 1 hepatorenal syndrome (HRS)." | 5.11 | The effects of chronic treatment with octreotide versus octreotide plus midodrine on systemic hemodynamics and renal hemodynamics and function in nonazotemic cirrhotic patients with ascites. ( Al Bokharhii, J; Economou, M; Fotopoulos, A; Kalambokis, G; Katsaraki, A; Pappas, C; Tsianos, EV, 2005) |
| " Midodrine and octreotide were dosed to obtain a stable increase of at least 15 mm Hg of mean arterial pressure." | 2.69 | Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide. ( Amodio, P; Angeli, P; Caregaro, L; Craighero, R; Gatta, A; Gerunda, G; Maffei-Faccioli, A; Merenda, R; Roner, P; Sticca, A; Volpin, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wong, F | 2 |
| Raina, N | 1 |
| Richardson, R | 1 |
| Pantea, L | 1 |
| Sniderman, K | 1 |
| Kalambokis, G | 1 |
| Economou, M | 1 |
| Fotopoulos, A | 1 |
| Al Bokharhii, J | 1 |
| Pappas, C | 1 |
| Katsaraki, A | 1 |
| Tsianos, EV | 1 |
| Green, J | 1 |
| Better, OS | 1 |
| Pasqualetti, P | 1 |
| Festuccia, V | 1 |
| Collacciani, A | 1 |
| Di Lauro, G | 1 |
| Casale, R | 1 |
| Saló, J | 1 |
| Fernández-Esparrach, G | 1 |
| Ginès, P | 1 |
| Ginès, A | 1 |
| Guevara, M | 1 |
| Sort, P | 1 |
| Jiménez, W | 1 |
| Arroyo, V | 1 |
| Rivera, F | 1 |
| Rodés, J | 1 |
| Angeli, P | 1 |
| Volpin, R | 1 |
| Gerunda, G | 1 |
| Craighero, R | 1 |
| Roner, P | 1 |
| Merenda, R | 1 |
| Amodio, P | 1 |
| Sticca, A | 1 |
| Caregaro, L | 1 |
| Maffei-Faccioli, A | 1 |
| Gatta, A | 1 |
| Knotek, M | 1 |
| Rogachev, B | 1 |
| Schrier, RW | 1 |
| Fernandez-Seara, J | 1 |
| Prieto, J | 1 |
| Quiroga, J | 1 |
| Zozaya, JM | 1 |
| Cobos, MA | 1 |
| Rodriguez-Eire, JL | 1 |
| Garcia-Plaza, A | 1 |
| Leal, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Midodrine and Albumin for Cirrhotic Patients in the Waiting List for Liver Transplantation[NCT00839358] | Phase 4 | 199 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| Vasoconstrictors as Alternatives to Albumin After Large Volume Paracentesis in Cirrhosis[NCT00108355] | Phase 4 | 29 participants (Actual) | Interventional | 2003-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Defined as an increase in Plasma Renin Activity (PRA) by >50% from baseline to a level > 4 ng/mL/h at post-paracentesis day (NCT00108355)
Timeframe: 6 days after paracentesis
| Intervention | participants (Number) |
|---|---|
| Albumin (Control Group) | 2 |
| Vasoconstrictor (Treatment Group) | 2 |
Comparison between Albumin (Control group) and Vasoconstrictor (Treatment group) (NCT00108355)
Timeframe: Variable depending on the patient, average 10 days
| Intervention | days (Median) |
|---|---|
| Albumin (Control Group) | 10 |
| Vasoconstrictor (Treatment Group) | 8 |
2 reviews available for aldosterone and Hepatorenal Syndrome
| Article | Year |
|---|---|
Circulatory disturbance and renal dysfunction in liver disease and in obstructive jaundice.
Topics: Adult; Aldosterone; Algorithms; Blood Circulation; Cholestasis; Diagnosis, Differential; Glomerular | 1994 |
Update on peripheral arterial vasodilation, ascites and hepatorenal syndrome in cirrhosis.
Topics: Aldosterone; Animals; Ascites; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Nitric Oxide; Peritoni | 2000 |
3 trials available for aldosterone and Hepatorenal Syndrome
| Article | Year |
|---|---|
Midodrine, octreotide, albumin, and TIPS in selected patients with cirrhosis and type 1 hepatorenal syndrome.
Topics: Adrenergic alpha-Agonists; Albumins; Aldosterone; Ascites; Blood Volume; Creatinine; Drug Therapy, C | 2004 |
The effects of chronic treatment with octreotide versus octreotide plus midodrine on systemic hemodynamics and renal hemodynamics and function in nonazotemic cirrhotic patients with ascites.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Aged; Aldosterone; Blood Flow Velocity; Drug | 2005 |
Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide.
Topics: Aldosterone; Ascites; Blood Pressure; Diuresis; Electrolytes; Gastrointestinal Agents; Glomerular Fi | 1999 |
4 other studies available for aldosterone and Hepatorenal Syndrome
| Article | Year |
|---|---|
Molecular adsorbent recirculating system is ineffective in the management of type 1 hepatorenal syndrome in patients with cirrhosis with ascites who have failed vasoconstrictor treatment.
Topics: Adult; Aged; Aldosterone; Female; Glomerular Filtration Rate; Hemodynamics; Hepatorenal Syndrome; Hu | 2010 |
Circadian rhythms of plasma atriopeptin, plasma renin activity and plasma aldosterone in patients with hepatorenal syndrome.
Topics: Aldosterone; Atrial Natriuretic Factor; Circadian Rhythm; Female; Hepatorenal Syndrome; Humans; Line | 1997 |
Urinary endothelin-like immunoreactivity in patients with cirrhosis.
Topics: Adult; Aldosterone; Ascites; Atrial Natriuretic Factor; Endothelins; Female; Hepatorenal Syndrome; H | 1997 |
Systemic and regional hemodynamics in patients with liver cirrhosis and ascites with and without functional renal failure.
Topics: Aldosterone; Female; Hemodynamics; Hepatorenal Syndrome; Humans; Kidney Diseases; Kidney Function Te | 1989 |