aldosterone has been researched along with Heart Diseases in 84 studies
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
Excerpt | Relevance | Reference |
---|---|---|
" Angiotensin II and aldosterone often collaborate in pathological situations to induce hypertrophy of cardiomyocytes, vascular inflammation, perivascular and interstitial fibrosis, and microvascular rarefaction." | 8.89 | Aldosterone mediates cardiac fibrosis in the setting of hypertension. ( Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL, 2013) |
"Leptin is a newly described regulator of aldosterone synthesis that acts directly on adrenal glomerulosa cells to increase CYP11B2 expression and enhance aldosterone production via calcium-dependent mechanisms." | 5.42 | Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis. ( Antonova, G; Belin de Chantemèle, EJ; Bollag, WB; Filosa, JA; Gomez-Sanchez, CE; Groenendyk, J; Huby, AC, 2015) |
"Telmisartan was administered to renovascular hypertensive rats at either a high dose (5 mg per kg per day; high-T group) or a low dose (0." | 5.35 | Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy, in renovascular hypertensive rats. ( Hongo, K; Kawai, M; Komukai, K; Mochizuki, S; Morimoto, S; Nagai, M; Seki, S; Taniguchi, I; Yoshimura, M, 2009) |
"Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations." | 5.34 | Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study. ( Agostinelli, L; Boscaro, M; Giacchetti, G; Mantero, F; Rilli, S; Ronconi, V; Turchi, F, 2007) |
" Angiotensin II and aldosterone often collaborate in pathological situations to induce hypertrophy of cardiomyocytes, vascular inflammation, perivascular and interstitial fibrosis, and microvascular rarefaction." | 4.89 | Aldosterone mediates cardiac fibrosis in the setting of hypertension. ( Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL, 2013) |
"Hypertension was induced by continuous angiotensin II (Ang II) infusion via osmotic mini-pumps over 4 weeks." | 3.77 | Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage. ( Cordasic, N; Daniel, C; Hartner, A; Heusinger-Ribeiro, J; Hilgers, KF; Klanke, B; Knier, B; Veelken, R, 2011) |
"Primary aldosteronism is common and contributes to adverse cardiovascular, kidney, and metabolic outcomes." | 2.66 | MANAGEMENT OF ENDOCRINE DISEASE: The role of surgical adrenalectomy in primary aldosteronism. ( Hundemer, GL; Vaidya, A, 2020) |
"Aldosterone is a mineralocorticoid hormone with various direct harmful effects on the myocardium, including increased reactive oxygen species (ROS) generation, which contributes significantly to cardiac mitochondrial dysfunction and cardiac aging." | 2.61 | Adrenal βarrestin1 targeting for tobacco-associated cardiac dysfunction treatment: Aldosterone production as the mechanistic link. ( Lymperopoulos, A; Mitaishvili, E; Solesio, ME, 2019) |
"Stroke is a severe and frequent complication of Fabry disease (FD), affecting both males and females." | 1.56 | Fabry disease patients have an increased risk of stroke in the COVID-19 ERA. A hypothesis. ( Bonardo, P; Reisin, RC; Rozenfeld, P, 2020) |
"Primary aldosteronism is characterized by excess aldosterone (ALDO) secretion independent of the renin-angiotensin system and accounts for approximately 10% of hypertension cases." | 1.46 | Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats. ( Ball, JP; Hall, ME; Kc, R; Marañon, RO; Reckelhoff, JF; Romero, DG; Syed, M; Yanes Cardozo, LL, 2017) |
"Leptin is a newly described regulator of aldosterone synthesis that acts directly on adrenal glomerulosa cells to increase CYP11B2 expression and enhance aldosterone production via calcium-dependent mechanisms." | 1.42 | Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis. ( Antonova, G; Belin de Chantemèle, EJ; Bollag, WB; Filosa, JA; Gomez-Sanchez, CE; Groenendyk, J; Huby, AC, 2015) |
"Primary hyperaldosteronism is the most common cause of secondary hypertension." | 1.39 | Hypertension caused by primary hyperaldosteronism: increased heart damage and cardiovascular risk. ( Abad-Cardiel, M; Alvarez-Álvarez, B; Fernández, C; Fernández-Cruz, A; Luque-Fernandez, L; Martell-Claros, N, 2013) |
"Primary aldosteronism (PA) is sometimes associated with the autonomous secretion of cortisol." | 1.37 | Cardiovascular complications of patients with aldosteronism associated with autonomous cortisol secretion. ( Hashimoto, K; Monden, T; Mori, M; Nakajima, Y; Okada, S; Ozawa, A; Satoh, T; Shibusawa, N; Taguchi, R; Yamada, M, 2011) |
"Both fibrinogen and PAI-1 were independent predictors of the presence of organ damage and their inclusion in a multivariate model eliminated PRA and aldosterone as independent predictors." | 1.35 | Relationship of plasma renin with a prothrombotic state in hypertension: relevance for organ damage. ( Casanova-Borca, A; Catena, C; Chiuch, A; Colussi, G; Di Fabio, A; Nadalini, E; Novello, M; Sechi, LA; Uzzau, A, 2008) |
"Telmisartan was administered to renovascular hypertensive rats at either a high dose (5 mg per kg per day; high-T group) or a low dose (0." | 1.35 | Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy, in renovascular hypertensive rats. ( Hongo, K; Kawai, M; Komukai, K; Mochizuki, S; Morimoto, S; Nagai, M; Seki, S; Taniguchi, I; Yoshimura, M, 2009) |
"Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations." | 1.34 | Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study. ( Agostinelli, L; Boscaro, M; Giacchetti, G; Mantero, F; Rilli, S; Ronconi, V; Turchi, F, 2007) |
"Aldosterone plays a key role in the pathogenesis of Ang II-induced organ damage." | 1.33 | Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage. ( Al-Saadi, N; Dechend, R; Fiebeler, A; Hilfenhaus, G; Jeng, AY; Luft, FC; Maser-Gluth, C; Meiners, S; Muller, DN; Nussberger, J; Rong, S; Shagdarsuren, E; Webb, RL; Wellner, M, 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 33 (39.29) | 18.7374 |
1990's | 3 (3.57) | 18.2507 |
2000's | 18 (21.43) | 29.6817 |
2010's | 25 (29.76) | 24.3611 |
2020's | 5 (5.95) | 2.80 |
Authors | Studies |
---|---|
Han, Y | 3 |
Xian, Y | 3 |
Gao, X | 3 |
Qiang, P | 3 |
Hao, J | 3 |
Yang, F | 3 |
Shimosawa, T | 3 |
Chang, Y | 3 |
Xu, Q | 3 |
Williams, GH | 2 |
Chapman, K | 1 |
Hundemer, GL | 1 |
Vaidya, A | 1 |
Hill, MA | 1 |
Jaisser, F | 2 |
Sowers, JR | 1 |
Reisin, RC | 1 |
Rozenfeld, P | 1 |
Bonardo, P | 1 |
Ball, JP | 1 |
Syed, M | 1 |
Marañon, RO | 1 |
Hall, ME | 1 |
Kc, R | 1 |
Reckelhoff, JF | 1 |
Yanes Cardozo, LL | 1 |
Romero, DG | 1 |
Zhang, YD | 1 |
Ding, XJ | 1 |
Dai, HY | 1 |
Peng, WS | 1 |
Guo, NF | 1 |
Zhang, Y | 2 |
Zhou, QL | 1 |
Chen, XL | 1 |
Kesireddy, V | 1 |
Tan, Y | 1 |
Kline, D | 1 |
Brock, G | 1 |
Odei, JB | 1 |
Kluwe, B | 1 |
Effoe, VS | 1 |
Echouffo Tcheugui, JB | 1 |
Kalyani, RR | 1 |
Sims, M | 1 |
Taylor, HA | 1 |
Mongraw-Chaffin, M | 1 |
Akhabue, E | 1 |
Joseph, JJ | 1 |
Solesio, ME | 1 |
Mitaishvili, E | 1 |
Lymperopoulos, A | 1 |
Ocello, A | 1 |
La Rosa, S | 1 |
Fiorini, F | 1 |
Randone, S | 1 |
Maccarrone, R | 1 |
Battaglia, G | 1 |
Granata, A | 1 |
Azibani, F | 1 |
Fazal, L | 1 |
Chatziantoniou, C | 1 |
Samuel, JL | 1 |
Delcayre, C | 1 |
Hattori, T | 1 |
Murase, T | 1 |
Sugiura, Y | 1 |
Nagasawa, K | 1 |
Takahashi, K | 1 |
Ohtake, M | 2 |
Miyachi, M | 1 |
Murohara, T | 1 |
Nagata, K | 1 |
Bauersachs, J | 1 |
Toto, R | 1 |
Huby, AC | 1 |
Antonova, G | 1 |
Groenendyk, J | 1 |
Gomez-Sanchez, CE | 1 |
Bollag, WB | 1 |
Filosa, JA | 1 |
Belin de Chantemèle, EJ | 1 |
Peng, W | 1 |
Ao, X | 1 |
Dai, H | 1 |
Yuan, L | 1 |
Huang, X | 1 |
Zhou, Q | 1 |
Cannavo, A | 1 |
Liccardo, D | 1 |
Eguchi, A | 1 |
Elliott, KJ | 1 |
Traynham, CJ | 1 |
Ibetti, J | 1 |
Eguchi, S | 1 |
Leosco, D | 1 |
Ferrara, N | 1 |
Rengo, G | 1 |
Koch, WJ | 1 |
Lother, A | 1 |
Hein, L | 1 |
Lasheen, NN | 1 |
Mohamed, GF | 1 |
Sechi, LA | 2 |
Novello, M | 1 |
Colussi, G | 2 |
Di Fabio, A | 1 |
Chiuch, A | 1 |
Nadalini, E | 1 |
Casanova-Borca, A | 1 |
Uzzau, A | 1 |
Catena, C | 2 |
Wu, R | 1 |
Zeng, Y | 1 |
Kawai, M | 1 |
Hongo, K | 1 |
Komukai, K | 1 |
Morimoto, S | 1 |
Nagai, M | 1 |
Seki, S | 1 |
Taniguchi, I | 1 |
Mochizuki, S | 1 |
Yoshimura, M | 1 |
Kubzansky, LD | 1 |
Adler, GK | 2 |
Cetrullo, S | 1 |
Facchini, A | 1 |
Stanic, I | 1 |
Tantini, B | 1 |
Pignatti, C | 1 |
Caldarera, CM | 1 |
Flamigni, F | 1 |
López, B | 1 |
González, A | 1 |
Díez, J | 1 |
Radović, M | 2 |
Damjanović, S | 1 |
Nale, D | 1 |
Mićić, S | 1 |
Vučović, D | 1 |
Nakajima, Y | 1 |
Yamada, M | 1 |
Taguchi, R | 1 |
Satoh, T | 1 |
Hashimoto, K | 1 |
Ozawa, A | 1 |
Shibusawa, N | 1 |
Okada, S | 1 |
Monden, T | 1 |
Mori, M | 1 |
Knier, B | 1 |
Cordasic, N | 1 |
Klanke, B | 1 |
Heusinger-Ribeiro, J | 1 |
Daniel, C | 1 |
Veelken, R | 1 |
Hartner, A | 1 |
Hilgers, KF | 1 |
Marzano, L | 1 |
Luther, JM | 1 |
Luo, P | 1 |
Wang, Z | 1 |
Cohen, SE | 1 |
Kim, HS | 1 |
Fogo, AB | 1 |
Brown, NJ | 1 |
Brem, AS | 1 |
Nagase, M | 1 |
Abad-Cardiel, M | 1 |
Alvarez-Álvarez, B | 1 |
Luque-Fernandez, L | 1 |
Fernández, C | 1 |
Fernández-Cruz, A | 1 |
Martell-Claros, N | 1 |
Firsov, D | 1 |
Muller, OG | 1 |
White, PC | 1 |
Pearce, D | 1 |
Bhargava, A | 1 |
Cole, TJ | 1 |
Fiebeler, A | 2 |
Haller, H | 1 |
Hostetter, TH | 1 |
Ibrahim, HN | 1 |
BUCHBORN, E | 3 |
KOCZOREK, KR | 3 |
KOHLER, M | 2 |
WOLFF, HP | 3 |
DI PERRI, T | 2 |
GUIDERI, R | 2 |
RAVENNI, G | 2 |
MONCIATTI, C | 1 |
BIANCHI, V | 2 |
SANDERS, LL | 1 |
MELBY, JC | 1 |
HANADA, M | 1 |
SAMBHI, MP | 1 |
VENNING, EH | 1 |
BECK, JC | 1 |
HALL, CE | 1 |
HALL, O | 1 |
Van Den Meiracker, AH | 1 |
Huizenga, AT | 1 |
Boomsma, F | 1 |
Mitka, M | 1 |
Nussberger, J | 1 |
Shagdarsuren, E | 1 |
Rong, S | 1 |
Hilfenhaus, G | 1 |
Al-Saadi, N | 1 |
Dechend, R | 1 |
Wellner, M | 1 |
Meiners, S | 1 |
Maser-Gluth, C | 1 |
Jeng, AY | 1 |
Webb, RL | 1 |
Luft, FC | 1 |
Muller, DN | 1 |
Sun, Y | 1 |
Weber, KT | 1 |
Lahera, V | 1 |
Cachofeiro, V | 1 |
Balfagon, G | 1 |
Rodicio, JL | 1 |
Giacchetti, G | 1 |
Ronconi, V | 1 |
Turchi, F | 1 |
Agostinelli, L | 1 |
Mantero, F | 1 |
Rilli, S | 1 |
Boscaro, M | 1 |
Kagiyama, S | 1 |
Matsumura, K | 1 |
Fukuhara, M | 1 |
Sakagami, K | 1 |
Fujii, K | 1 |
Iida, M | 1 |
Funder, JW | 1 |
Funck, RC | 1 |
Wilke, A | 1 |
Rupp, H | 1 |
Brilla, CG | 1 |
Lijnen, P | 1 |
Petrov, V | 1 |
Stowasser, M | 1 |
Martinez, DV | 1 |
Rocha, R | 1 |
Matsumura, M | 1 |
Oestreicher, E | 1 |
Ochoa-Maya, M | 1 |
Roubsanthisuk, W | 1 |
Knowlen, GG | 1 |
Kittleson, MD | 1 |
Nachreiner, RF | 1 |
Eyster, GE | 1 |
Zweifler, AJ | 1 |
Esler, M | 1 |
Shushliapin, OI | 1 |
Stimpel, M | 1 |
Kaufmann, W | 2 |
Wambach, G | 1 |
Grimaldi, A | 1 |
Pruszczynski, W | 1 |
Thervet, F | 1 |
Ardaillou, R | 1 |
Regan, TJ | 1 |
Pathan, A | 1 |
Weisse, AB | 1 |
Eaddy, C | 1 |
Torres, R | 1 |
Jayle, MF | 1 |
Legrand, JC | 1 |
Pasqualini, JR | 1 |
Cruz, IA | 1 |
Dillard, MG | 1 |
Hosten, AO | 1 |
Dioguardi, N | 1 |
Iimura, O | 2 |
Miyahara, M | 1 |
Kukuiri, T | 1 |
Abe, H | 1 |
Ueda, T | 1 |
Weil, MH | 1 |
Shubin, H | 1 |
Friedberg, CK | 1 |
Yoshida, H | 1 |
Mizukoshi, H | 1 |
Araki, Y | 1 |
Oelert, H | 1 |
Jick, H | 1 |
Müller, C | 2 |
Lutz, H | 2 |
Schmitz, W | 2 |
Reiss, F | 2 |
Ito, T | 1 |
Nakamura, K | 1 |
Kinouchi, T | 1 |
Kurosawa, T | 1 |
Oshima, M | 1 |
Manta, I | 1 |
Hodîrnău, A | 1 |
Proinov, I | 1 |
Băltescu, V | 1 |
Schneider, E | 1 |
Barbi, G | 1 |
Giocoli, G | 1 |
Cavina, G | 1 |
Sardini, D | 1 |
Vinogradov, AV | 1 |
Sycheva, IM | 1 |
Kiseleva, ZM | 1 |
Schaison, G | 1 |
Kinoshita, M | 1 |
Siegenthaler, W | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055] | Phase 4 | 75 participants (Anticipated) | Interventional | 2023-08-25 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
27 reviews available for aldosterone and Heart Diseases
Article | Year |
---|---|
MANAGEMENT OF ENDOCRINE DISEASE: The role of surgical adrenalectomy in primary aldosteronism.
Topics: Adrenalectomy; Aldosterone; Endocrine System Diseases; Heart Diseases; Humans; Hyperaldosteronism; K | 2020 |
Role of the vascular endothelial sodium channel activation in the genesis of pathologically increased cardiovascular stiffness.
Topics: Aldosterone; Coronary Circulation; Coronary Vessels; Endothelial Cells; Epithelial Sodium Channels; | 2022 |
Adrenal βarrestin1 targeting for tobacco-associated cardiac dysfunction treatment: Aldosterone production as the mechanistic link.
Topics: Adrenal Glands; Aldosterone; beta-Arrestin 1; Cotinine; Heart Diseases; Humans; Molecular Targeted T | 2019 |
[Antifibrotic renal role of mineralcorticoid receptor antagonists].
Topics: Aldosterone; Body Fluids; Cardiovascular Diseases; Clinical Trials as Topic; Cytokines; Diabetic Nep | 2019 |
Aldosterone mediates cardiac fibrosis in the setting of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Heart Diseases; Humans; Hy | 2013 |
Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Clinical Trials as Topi | 2015 |
Vascular Mineralocorticoid Receptors: Linking Risk Factors, Hypertension, and Heart Disease.
Topics: Aldosterone; Blood Vessels; Heart Diseases; Humans; Hypertension; Receptors, Mineralocorticoid; Risk | 2016 |
Aldosterone: a forgotten mediator of the relationship between psychological stress and heart disease.
Topics: Aldosterone; Animals; Brain; Heart Diseases; Humans; Models, Biological; Stress, Psychological | 2010 |
Aldosterone and the heart: from basic research to clinical evidence.
Topics: Aldosterone; Animals; Heart; Heart Diseases; Humans; Hyperaldosteronism | 2012 |
[Mineralocorticoid receptor: an update].
Topics: Aldosterone; Animals; Heart Diseases; Humans; Kidney Diseases; Mineralocorticoid Receptor Antagonist | 2012 |
Aldosterone action in the heart.
Topics: Aldosterone; Animals; Cardiovascular Physiological Phenomena; Heart; Heart Diseases; Humans | 2003 |
Aldosterone: direct effects on and production by the heart.
Topics: Aldosterone; Animals; Cardiovascular Physiological Phenomena; Cytochrome P-450 CYP11B2; Electrophysi | 2003 |
Aldosterone: its receptor, target genes, and actions.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Brain; Chromatin; Epithelium; Gen | 2003 |
Participation of the mineralocorticoid receptor in cardiac and vascular remodeling.
Topics: Aldosterone; Animals; Heart Diseases; Humans; Kidney; Mice; Mineralocorticoid Receptor Antagonists; | 2003 |
Aldosterone in chronic kidney and cardiac disease.
Topics: Aldosterone; Chronic Disease; Heart Diseases; Humans; Kidney Diseases | 2003 |
[Profibrotic effects of aldosterone].
Topics: Aldosterone; Animals; Fibrosis; Heart Diseases; Humans; Mineralocorticoid Receptor Antagonists; Myoc | 2004 |
Aldosterone and its blockade: a cardiovascular and renal perspective.
Topics: Aldosterone; Cardiovascular Physiological Phenomena; Heart Diseases; Humans; Kidney; Kidney Diseases | 2006 |
Mineralocorticoid receptors and hypertension.
Topics: Aldosterone; Animals; Epithelium; Heart Diseases; Hypertension; Rats; Receptors, Glucocorticoid; Rec | 1995 |
Regulation and role of myocardial collagen matrix remodeling in hypertensive heart disease.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Cells, Cultured; Collagen; Collagenases; Heart; Heart D | 1997 |
Induction of cardiac fibrosis by aldosterone.
Topics: Aldosterone; Animals; Collagen; Fibroblasts; Fibrosis; Heart; Heart Diseases; Humans; Mineralocortic | 2000 |
New perspectives on the role of aldosterone excess in cardiovascular disease.
Topics: Aldosterone; Animals; Heart Diseases; Humans; Hyperaldosteronism | 2001 |
[Recent data on the physiopathologic metabolism of aldosterone].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Aorta; Edema; Female; Heart Disea | 1967 |
[Heart diseases, hypertension and hormonal anomaly--with special reference to aldosterone and catecholamine].
Topics: Aldosterone; Catecholamines; Heart Diseases; Humans; Hypertension; Hyperthyroidism | 1967 |
Shock following acute myocardial infarction. Current understanding of hemodynamic mechanisms.
Topics: Acidosis; Aldosterone; Animals; Arrhythmias, Cardiac; Arteries; Blood Flow Velocity; Blood Pressure; | 1968 |
Edema and pulmonary edema: pathologic physiology and differential diagnosis.
Topics: Adrenal Glands; Aldosterone; Diagnosis, Differential; Edema; Extracellular Space; Female; Heart Dise | 1971 |
[The third factor].
Topics: Aldosterone; Animals; Biological Assay; Dogs; Extracorporeal Circulation; Female; Glomerular Filtrat | 1971 |
[Aldosterone and aldosterone antagonists in surgery].
Topics: Adult; Aldosterone; Blood Volume; Brain Edema; Cardiac Surgical Procedures; Child; Digitalis Glycosi | 1971 |
1 trial available for aldosterone and Heart Diseases
Article | Year |
---|---|
Modulation of aldosterone release by epidural analgesia impacts brain natriuretic peptide: a link to stress cardiomyopathy? Pilot study.
Topics: Aldosterone; Analgesia, Epidural; Anesthesia, General; Heart Diseases; Humans; Male; Middle Aged; Na | 2011 |
56 other studies available for aldosterone and Heart Diseases
Article | Year |
---|---|
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Aldosterone: The Missing Cardiorenal Link.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Heart Diseases; Humans; Kidney Diseases; Mine | 2019 |
Cardiac gluco- and mineralocorticoid receptors: From development to pathology.
Topics: Aldosterone; Heart Diseases; Humans; Hydrocortisone; Receptors, Glucocorticoid; Receptors, Mineraloc | 2021 |
Fabry disease patients have an increased risk of stroke in the COVID-19 ERA. A hypothesis.
Topics: Aldosterone; Angiotensin-Converting Enzyme 2; COVID-19; Endothelium, Vascular; Fabry Disease; Female | 2020 |
Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats.
Topics: Aldosterone; Animals; Gene Expression Regulation; Heart; Heart Diseases; Hyperaldosteronism; Hyperte | 2017 |
SB-216763, a GSK-3β inhibitor, protects against aldosterone-induced cardiac, and renal injury by activating autophagy.
Topics: Aldosterone; Animals; Autophagy; Cytokines; Fibrosis; Glycogen Synthase Kinase 3 beta; Heart Disease | 2018 |
The Association of Life's Simple 7 with Aldosterone among African Americans in the Jackson Heart Study.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Black or African American; Blood Glucose; Female; Heart | 2019 |
Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Echocardiography; Endoth | 2014 |
Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis.
Topics: Adipocytes; Adrenal Cortex; Aldosterone; Animals; Cell Line, Tumor; Cells, Cultured; Endothelium, Va | 2015 |
TAK-242, a Toll-Like Receptor 4 Antagonist, Protects against Aldosterone-Induced Cardiac and Renal Injury.
Topics: Acute Kidney Injury; Aldosterone; Animals; Cytokines; Heart Diseases; Hemodynamics; Inflammation; Ma | 2015 |
Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases.
Topics: Aldosterone; Animals; Arrestins; beta-Arrestins; Cell Culture Techniques; Cell Movement; G-Protein-C | 2016 |
Possible mechanisms of cardiac contractile dysfunction and electrical changes in ammonium chloride induced chronic metabolic acidosis in Wistar rats.
Topics: Acidosis; Aldosterone; Ammonium Chloride; Animals; Chronic Disease; Echocardiography; Electrocardiog | 2016 |
Relationship of plasma renin with a prothrombotic state in hypertension: relevance for organ damage.
Topics: Adult; Aldosterone; Algorithms; Analysis of Variance; Biomarkers; Cerebrovascular Disorders; Cross-S | 2008 |
Does angiotensin II-aldosterone have a role in radiation-induced heart disease?
Topics: Aldosterone; Angiotensin II; Animals; Dose-Response Relationship, Radiation; Heart Diseases; Myocard | 2009 |
Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy, in renovascular hypertensive rats.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Vess | 2009 |
Difluoromethylornithine inhibits hypertrophic, pro-fibrotic and pro-apoptotic actions of aldosterone in cardiac cells.
Topics: Aldosterone; Animals; Apoptosis; Biogenic Polyamines; Cells, Cultured; Eflornithine; Fibrosis; Gene | 2010 |
Circulating biomarkers of collagen metabolism in cardiac diseases.
Topics: Aldosterone; Biomarkers; Carrier Proteins; Collagen; Connective Tissue Growth Factor; Heart Diseases | 2010 |
Cardiovascular complications of patients with aldosteronism associated with autonomous cortisol secretion.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Circadian Rhythm; Cross-Sectional Studies; Female; Hear | 2011 |
Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrinolysin; Fibrosis | 2011 |
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; D | 2012 |
Targeting activated mineralocorticoid receptor: Occam's razor revisited.
Topics: Aldosterone; Angiotensin II; Animals; Heart Diseases; Kidney Diseases; Mineralocorticoid Receptor An | 2012 |
Hypertension caused by primary hyperaldosteronism: increased heart damage and cardiovascular risk.
Topics: Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Female; Heart Diseases; | 2013 |
[Aldosterone activity and sodium retention in heart disease and its pathophysiologic significance].
Topics: Aldosterone; Heart Diseases; Humans; Hypernatremia; Ions; Sodium; Sodium, Dietary | 1956 |
[Aldosterone activity and sodium retention in heart disease and its pathophysiologic significance].
Topics: Aldosterone; Heart Diseases; Humans; Hypernatremia; Ions; Sodium; Sodium, Dietary | 1956 |
[Aldosterone activity and sodium retention in heart disease and its pathophysiologic significance].
Topics: Aldosterone; Heart Diseases; Humans; Hypernatremia; Ions; Sodium; Sodium, Dietary | 1956 |
[Aldosterone activity and sodium retention in heart disease and its pathophysiologic significance].
Topics: Aldosterone; Heart Diseases; Humans; Hypernatremia; Ions; Sodium; Sodium, Dietary | 1956 |
Hyperaldosteronism in heart disease.
Topics: Aldosterone; Heart Diseases; Heart Failure; Humans; Hyperaldosteronism | 1957 |
[The pathogenesis of nyctohemeral variations in urinary aldosterone and in the elimination of water and sodium in heart disease patients].
Topics: Aldosterone; Biological Transport; Heart Diseases; Humans; Ions; Sodium; Sodium, Dietary; Water | 1958 |
[Nocturnal urination of cardiac patients; study of the pathogenesis as a function of aldosterone secretion].
Topics: Aldosterone; Heart Diseases; Humans; Posture; Urination | 1959 |
ALDOSTERONE AND THE EDEMA OF CONGESTIVE HEART FAILURE.
Topics: Aldosterone; Chromatography; Diuretics; Edema; Geriatrics; Heart Diseases; Heart Failure; Hypertensi | 1964 |
[ALDOSTERONE SECRETION RATE IN VARIOUS DISEASES].
Topics: Aldosterone; Cushing Syndrome; Diabetic Nephropathies; Heart Diseases; Humans; Hyperaldosteronism; H | 1963 |
ALDOSTERONE SECRETION RATE AND ELECTROLYTE BALANCE STUDIES ON THREE PATIENTS WITH HYPERTENSION. INFLUENCE OF GUANETHIDINE, HYDRALAZINE AND METHYCLOTHIAZIDE.
Topics: Aldosterone; Diet, Sodium-Restricted; Diuretics; Guanethidine; Heart Diseases; Humans; Hydralazine; | 1964 |
HYPERTENSION AND HYPERSALIMENTATION. I. ALDOSTERONE HYPERTENSION.
Topics: Adrenal Glands; Aldosterone; Arteritis; Diet; Heart Diseases; Hypertension; Kidney; Metabolism; Myoc | 1965 |
Scientists probe aldosterone's role in hypertension and heart disease.
Topics: Aldosterone; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Heart Diseases; Humans; | 2004 |
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Animals, Genet | 2005 |
Animal models of cardiac fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Diseases; | 2005 |
Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Glucose | 2007 |
Aldosterone-and-salt-induced cardiac fibrosis is independent from angiotensin II type 1a receptor signaling in mice.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blotting, Western; Ca | 2007 |
Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading.
Topics: Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Eplerenone; H | 2002 |
Comparison of plasma aldosterone concentration among clinical status groups of dogs with chronic heart failure.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; | 1983 |
Factors influencing the choice of antihypertensive agents.
Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications; | 1976 |
[Change of certain humoral and hemodynamic factors in chronic circulatory insufficiency].
Topics: Aldosterone; Blood Circulation; Female; Heart Diseases; Hemodynamics; Humans; Male; Renin | 1975 |
A symposium: International update--the important role of aldosterone and aldosterone antagonism in cardiovascular medicine. Based on symposia held in Brussels, Belgium and Newport Beach, California.
Topics: Aldosterone; Heart Diseases; Humans; Hypertension; Mineralocorticoid Receptor Antagonists | 1990 |
[Atrial natriuretic peptide (ANP) in essential hypertension: a humoral marker for salt sensitivity and hypertensive heart disease at a clinically asymptomatic stage?].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Female; Heart Disease | 1988 |
Antidiuretic hormone response to volume depletion in diabetic patients with cardiac autonomic dysfunction.
Topics: Adult; Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Blood Volume; Diabetic Neurop | 1985 |
The contribution of arterial pressure to the cardiac dysfunction of chronic alcoholism.
Topics: Adult; Alcoholism; Aldosterone; Blood Pressure; Catecholamines; Echocardiography; Electrolytes; Hear | 1985 |
Selective hypoaldosteronism: a case report and review of literature.
Topics: Adrenal Insufficiency; Adult; Aldosterone; Diabetes Complications; Heart Diseases; Humans; Hyperkale | 1974 |
[Edema in the patient with heart disease].
Topics: Aldosterone; Blood Pressure; Edema; Glomerular Filtration Rate; Heart Diseases; Heart Failure; Human | 1973 |
Actual incidence of secondary hypertension.
Topics: Adult; Aldosterone; Biopsy; Blood Pressure; Catecholamines; Cushing Syndrome; Diagnosis, Differentia | 1973 |
The use of glucocorticoids for diuresis in patients with fluid retention not resulting from renal disease.
Topics: Aldosterone; Chlorothiazide; Diuresis; Edema; Glomerular Filtration Rate; Glucocorticoids; Heart Dis | 1966 |
[Electrolyte changes in heart surgery with autogenous blood dilution perfusions].
Topics: Adolescent; Adult; Aldosterone; Child; Erythrocytes; Extracorporeal Circulation; Heart Defects, Cong | 1968 |
The role of aldosterone in the pathogenesis of congestive heart failure.
Topics: Aldosterone; Animals; Dogs; Edema; Female; Heart Diseases; Heart Failure; Humans; Mannitol; Potassiu | 1967 |
[Research on arterial hypertension. Significance of aldosterone, catecholamines, amino acids and some electrolytes in compensated and decompensated cardiac lesions].
Topics: Adult; Aged; Aldosterone; Amino Acids; Catecholamines; Coronary Disease; Electrolytes; Female; Heart | 1970 |
[Clinical evaluation of a new method for the determination of urinary aldosterone].
Topics: Aldosterone; Chromatography, Thin Layer; Edema; Female; Heart Diseases; Humans; Hyperaldosteronism; | 1971 |
[The significance of aldosterone in the pathogenesis of edema in cardiac insufficiency].
Topics: Adult; Aged; Aldosterone; Edema; Female; Heart Diseases; Heart Failure; Humans; Male; Middle Aged; P | 1967 |
[Physiopathology and treatment of hyponatremia (II)].
Topics: Adrenal Insufficiency; Aldosterone; Anesthesia; Diuretics; Heart Diseases; Humans; Hyperpituitarism; | 1968 |
[Electrolyte changes in heart surgery with autogenous blood dilution perfusions].
Topics: Adolescent; Adult; Aldosterone; Child; Erythrocytes; Extracorporeal Circulation; Heart Defects, Cong | 1968 |
Studies on cardiac output to blood volume, and renal circulation in chronic congestive heart failure.
Topics: Adult; Aged; Aldosterone; Arteriosclerosis; Blood Pressure; Blood Volume; Cardiac Output; Chronic Di | 1968 |
[Diuretic therapy of hydropic cardiac insufficiency].
Topics: Aldosterone; Diuretics; Edema; Heart Diseases; Humans; Sulfonamides; Sympatholytics | 1965 |