Page last updated: 2024-11-07

aldosterone and Glucose Intolerance

aldosterone has been researched along with Glucose Intolerance in 12 studies

Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.

Research Excerpts

ExcerptRelevanceReference
"Impaired glucose tolerance (IGT) is associated with cardiovascular risk factors, but the effects of pioglitazone and metformin on IGT are not well described."9.12Comparison of the effects of pioglitazone and metformin on insulin resistance and hormonal markers in patients with impaired glucose tolerance and early diabetes. ( Eguchi, K; Fukuda, T; Hoshide, S; Ishikawa, J; Kario, K; Numao, T; Shimada, K; Tomizawa, H, 2007)
"After the treatment of primary aldosteronism, glucose intolerance was improved in 66."5.56Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone-producing adenoma and idiopathic hyperaldosteronism. ( Fukuda, I; Moriya, A; Nagao, M; Oikawa, S; Okazaki-Hada, M; Sugihara, H, 2020)
"Impaired glucose tolerance (IGT) is associated with cardiovascular risk factors, but the effects of pioglitazone and metformin on IGT are not well described."5.12Comparison of the effects of pioglitazone and metformin on insulin resistance and hormonal markers in patients with impaired glucose tolerance and early diabetes. ( Eguchi, K; Fukuda, T; Hoshide, S; Ishikawa, J; Kario, K; Numao, T; Shimada, K; Tomizawa, H, 2007)
"These results demonstrates that hypertension and insulin resistance induced by COC is associated with increased cardiac RAS and PAI-1 gene expression, which is likely to be through corticosterone-dependent but not aldosterone-dependent mechanism."3.85Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. ( Kim, IK; Olatunji, LA; Seok, YM; Usman, TO, 2017)
"Patients with primary aldosteronism can have impaired pancreatic insulin release and reduction in insulin sensitivity."2.42The effect of aldosterone on glucose metabolism. ( Corry, DB; Tuck, ML, 2003)
"After the treatment of primary aldosteronism, glucose intolerance was improved in 66."1.56Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone-producing adenoma and idiopathic hyperaldosteronism. ( Fukuda, I; Moriya, A; Nagao, M; Oikawa, S; Okazaki-Hada, M; Sugihara, H, 2020)
"Aldosterone treatment impaired the rate of glucose uptake, oxidation, and insulin signal transduction in the gastrocnemius muscle through defective expression of IR, IRS-1, Akt, AS160, and GLUT4 genes."1.39Excess aldosterone-induced changes in insulin signaling molecules and glucose oxidation in gastrocnemius muscle of adult male rat. ( Balasubramanian, K; Mayilvanan, C; Sathish, S; Selvaraj, J, 2013)
"Primary hyperaldosteronism (PH), resulting in hypokalaemic hypertension, may be due to an aldosterone-producing adenoma (APA) or bilateral zona glomerulosa hyperplasia."1.34Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism. ( Boyne, MS; McKenzie, CA; Wright-Pascoe, R, 2007)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's6 (50.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Adegoke, TE1
Sabinari, IW1
Usman, TO2
Abdulkareem, TO1
Michael, OS1
Adeyanju, OA1
Dibia, C1
Omotoye, OO1
Oyabambi, AO1
Olatunji, LA2
Okazaki-Hada, M1
Moriya, A1
Nagao, M1
Oikawa, S1
Fukuda, I1
Sugihara, H1
Sherajee, SJ1
Rafiq, K1
Nakano, D1
Mori, H1
Kobara, H1
Hitomi, H1
Fujisawa, Y1
Kobori, H1
Masaki, T1
Nishiyama, A1
Armani, A1
Cinti, F1
Marzolla, V1
Morgan, J1
Cranston, GA1
Antelmi, A1
Carpinelli, G1
Canese, R1
Pagotto, U1
Quarta, C1
Malorni, W1
Matarrese, P1
Marconi, M1
Fabbri, A1
Rosano, G1
Cinti, S1
Young, MJ1
Caprio, M1
Seok, YM1
Kim, IK1
Mendez, N1
Halabi, D1
Spichiger, C1
Salazar, ER1
Vergara, K1
Alonso-Vasquez, P1
Carmona, P1
Sarmiento, JM1
Richter, HG1
Seron-Ferre, M1
Torres-Farfan, C1
Michailidou, Z1
Carter, RN1
Marshall, E1
Sutherland, HG1
Brownstein, DG1
Owen, E1
Cockett, K1
Kelly, V1
Ramage, L1
Al-Dujaili, EA1
Ross, M1
Maraki, I1
Newton, K1
Holmes, MC1
Seckl, JR1
Morton, NM1
Kenyon, CJ1
Chapman, KE1
Selvaraj, J1
Sathish, S1
Mayilvanan, C1
Balasubramanian, K1
Saha, S1
Schwarz, PE1
Bergmann, S1
Bornstein, SR1
Graessler, J1
Kopprasch, S1
Corry, DB1
Tuck, ML1
Eguchi, K1
Tomizawa, H1
Ishikawa, J1
Hoshide, S1
Numao, T1
Fukuda, T1
Shimada, K1
Kario, K1
McKenzie, CA1
Wright-Pascoe, R1
Boyne, MS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Metabolic Syndrome and Insulin Resistance in Primary Aldosteronism[NCT00173082]100 participants (Anticipated)Observational2005-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aldosterone and Glucose Intolerance

ArticleYear
The effect of aldosterone on glucose metabolism.
    Current hypertension reports, 2003, Volume: 5, Issue:2

    Topics: Aldosterone; Diabetes Mellitus; Glucose; Glucose Intolerance; Humans; Hyperaldosteronism; Insulin Re

2003

Trials

2 trials available for aldosterone and Glucose Intolerance

ArticleYear
Circulating very-low-density lipoprotein from subjects with impaired glucose tolerance accelerates adrenocortical cortisol and aldosterone synthesis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2013, Volume: 45, Issue:2

    Topics: Adrenal Cortex; Aged; Aldosterone; Cell Line; Glucose Intolerance; Glycated Hemoglobin; Humans; Hydr

2013
Comparison of the effects of pioglitazone and metformin on insulin resistance and hormonal markers in patients with impaired glucose tolerance and early diabetes.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:1

    Topics: Adiponectin; Aged; Aldosterone; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus; Fa

2007

Other Studies

9 other studies available for aldosterone and Glucose Intolerance

ArticleYear
Allopurinol and valproic acid improve cardiac triglyceride and Na
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:5

    Topics: Adenosine Triphosphatases; Aldosterone; Allopurinol; Animals; Contraceptives, Oral, Combined; Female

2022
Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone-producing adenoma and idiopathic hyperaldosteronism.
    Journal of diabetes investigation, 2020, Volume: 11, Issue:6

    Topics: Adenoma; Aldosterone; Biomarkers; Female; Follow-Up Studies; Glucose Intolerance; Humans; Hyperaldos

2020
Aldosterone aggravates glucose intolerance induced by high fructose.
    European journal of pharmacology, 2013, Nov-15, Volume: 720, Issue:1-3

    Topics: Aldosterone; Animals; Blood Glucose; Fructose; Glucose Intolerance; Glucose Tolerance Test; Immediat

2013
Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high-fat-diet-fed mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:8

    Topics: Adipocytes; Adipogenesis; Adipose Tissue, Brown; Adipose Tissue, White; Aldosterone; Androstenes; An

2014
Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder.
    Archives of physiology and biochemistry, 2017, Volume: 123, Issue:1

    Topics: Aldosterone; Animals; Ataxia Telangiectasia Mutated Proteins; Cardiovascular Diseases; Contraceptive

2017
Gestational Chronodisruption Impairs Circadian Physiology in Rat Male Offspring, Increasing the Risk of Chronic Disease.
    Endocrinology, 2016, Volume: 157, Issue:12

    Topics: Aldosterone; Animals; Blood Pressure; Body Temperature; Chronic Disease; Circadian Rhythm; CLOCK Pro

2016
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:11

    Topics: Adiposity; Aldosterone; Angiotensins; Animals; Blood Glucose; Blood Pressure; Cell Line; Diet; Dieta

2008
Excess aldosterone-induced changes in insulin signaling molecules and glucose oxidation in gastrocnemius muscle of adult male rat.
    Molecular and cellular biochemistry, 2013, Volume: 372, Issue:1-2

    Topics: Aldosterone; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Blood Glucose; CSK Tyrosine-Protei

2013
Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism.
    The West Indian medical journal, 2007, Volume: 56, Issue:3

    Topics: Adult; Aldosterone; Body Mass Index; Female; Glucose Intolerance; Humans; Hyperaldosteronism; Hypert

2007