aldosterone has been researched along with Genetic Predisposition in 65 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Functional changes in the kidneys of healthy men with (FH+) (n = 15) and without (FH-) (n = 15) family history of primary arterial hypertension were examined during administration of low-dose exogenous angiotensin II (A2) (1 ng/kg per min) before and after acute (1 mg intravenous enalaprilat) and chronic (7 days oral enalapril, 30 mg/day) angiotensin-converting enzyme (ACE) inhibition." | 7.72 | Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. ( Bock, A; Dieterle, T; Drewe, J; Gyr, K; Haberthür, C; Huber, PR; Martina, B; Schächinger, H, 2004) |
| "Smoking and dyslipidemia are more potent risk factors for nonfatal MI in males who have the -344C allele of CYP11B2." | 6.69 | Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction. ( Hautanen, A; Kayes, KM; Kupari, M; Manninen, V; Mänttäri, M; Rosenfeld, S; Tenkanen, L; Toivanen, P; White, PC, 1999) |
| "In the setting of primary aldosteronism, elevated aldosterone levels are associated with increased blood pressure." | 6.46 | Aldosterone and arterial hypertension. ( Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Ritz, E; Tomaschitz, A, 2010) |
| "Aldosterone treatment increased lipid content of plaques (2." | 5.39 | Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism. ( Armani, A; Bagley, J; Caprio, M; Carmeliet, P; Chen, WS; Galayda, C; Jaffe, IZ; McGraw, AP; Nickerson, H, 2013) |
| "1." | 5.37 | Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. ( Chen, HY; Gao, X; Li, XM; Ling, Y; Liu, Y; Lu, DR; Lu, ZQ; Yi, QL, 2011) |
| "The aldosterone level was comparable in both groups." | 5.35 | Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families. ( Poredos, P; Trojar, A; Zeljko, T; Zizek, B, 2008) |
| "Essential hypertension is a disease multifactorially triggered by genetic and environmental factors." | 5.34 | Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007) |
| "Aldosterone is a risk factor for stroke, and the literature suggests it may play a role in increasing the expression of the receptor for EGF (EGFR)." | 5.31 | Spironolactone reduces cerebral infarct size and EGF-receptor mRNA in stroke-prone rats. ( Dorrance, AM; Grekin, R; Osborn, HL; Webb, RC, 2001) |
| "Functional changes in the kidneys of healthy men with (FH+) (n = 15) and without (FH-) (n = 15) family history of primary arterial hypertension were examined during administration of low-dose exogenous angiotensin II (A2) (1 ng/kg per min) before and after acute (1 mg intravenous enalaprilat) and chronic (7 days oral enalapril, 30 mg/day) angiotensin-converting enzyme (ACE) inhibition." | 3.72 | Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. ( Bock, A; Dieterle, T; Drewe, J; Gyr, K; Haberthür, C; Huber, PR; Martina, B; Schächinger, H, 2004) |
| "Elevations in plasma aldosterone enhance stroke development within captopril-treated SHRSP through mechanisms that do not involve stimulation of mineralocorticoid receptors or the enhancement of hypertension." | 3.69 | The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. ( MacLeod, AB; Smeda, JS; Vasdev, S, 1997) |
| "Smoking and dyslipidemia are more potent risk factors for nonfatal MI in males who have the -344C allele of CYP11B2." | 2.69 | Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction. ( Hautanen, A; Kayes, KM; Kupari, M; Manninen, V; Mänttäri, M; Rosenfeld, S; Tenkanen, L; Toivanen, P; White, PC, 1999) |
| "Primary aldosteronism (PA) is the most common form of secondary hypertension affecting 5%-10% of patients with arterial hypertension." | 2.66 | Old and new genes in primary aldosteronism. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2020) |
| "Pseudohyperaldosteronism is characterized by a clinical picture of hyperaldosteronism with suppression of renin and aldosterone." | 2.53 | Syndromes that Mimic an Excess of Mineralocorticoids. ( Armanini, D; Sabbadin, C, 2016) |
| "Primary aldosteronism is the most common form of secondary hypertension and affects 8-13% of patients with hypertension." | 2.53 | Genetics of primary hyperaldosteronism. ( Dutta, RK; Gimm, O; Söderkvist, P, 2016) |
| "In the setting of primary aldosteronism, elevated aldosterone levels are associated with increased blood pressure." | 2.46 | Aldosterone and arterial hypertension. ( Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Ritz, E; Tomaschitz, A, 2010) |
| "Human hypertension affects affects more than 20% of the adult population in industrialized countries, and it is implicated in millions of deaths worldwide each year from stroke, heart failure and ischemic heart disease." | 2.44 | Genetics of arterial hypertension and hypotension. ( Rimmbach, C; Rosskopf, D; Schäfers, R; Schürks, M, 2007) |
| "APA cause primary aldosteronism (PA), which affect 3-10% of the hypertensive population." | 1.51 | Aldosterone-Producing Adenomas. ( Åkerström, T; Björklund, P; Hellman, P, 2019) |
| "The adrenal glands with adrenocortical adenomas from 79 black patients with primary aldosteronism were studied." | 1.51 | Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks. ( Barletta, JA; Cohen, DL; Demidowich, AP; Else, T; Gellert, L; Giordano, TJ; Gomez-Sanchez, CE; Luther, JM; Nanba, K; Omata, K; Rainey, WE; Stratakis, CA; Suzuki, M; Thompson, LDR; Tomlins, SA; Vaidya, A, 2019) |
| "Aldosterone values were significantly higher in animals carrying mutations in four different genes (Sspo, Dguok, Hoxaas2 and Clstn3) and associated statistically significant adrenal Cyp11b2 overexpression as well as increased ARR was present only in mice with Sspo mutation." | 1.46 | Genetic characterization of a mouse line with primary aldosteronism. ( Beuschlein, F; Hantel, C; Hrabě de Angelis, M; Perez-Rivas, LG; Rathkolb, B; Reincke, M; Rhayem, Y; Sabrautzki, S; Spyroglou, A, 2017) |
| "Primary aldosteronism is the most common form of secondary hypertension." | 1.40 | Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma. ( Allolio, B; Amar, L; Bernini, G; Beuschlein, F; Boulkroun, S; Cicala, MV; Fallo, F; Fernandes-Rosa, FL; Giacchetti, G; Jeunemaitre, X; Maccario, M; Mantero, F; Meatchi, T; Monticone, S; Mulatero, P; Quinkler, M; Reincke, M; Riester, A; Steichen, O; Strom, TM; Williams, TA; Zennaro, MC, 2014) |
| "Aldosterone treatment increased lipid content of plaques (2." | 1.39 | Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism. ( Armani, A; Bagley, J; Caprio, M; Carmeliet, P; Chen, WS; Galayda, C; Jaffe, IZ; McGraw, AP; Nickerson, H, 2013) |
| "Primary hyperaldosteronism, one cause of which is aldosterone-producing adenomas (APAs), may account for ≤5% to 10% of cases of essential hypertension." | 1.38 | Somatic mutations affecting the selectivity filter of KCNJ5 are frequent in 2 large unselected collections of adrenal aldosteronomas. ( Azizan, EA; Brown, MJ; Gordon, R; Kowalski, B; Murthy, M; O'Shaughnessy, KM; Stowasser, M; Xu, S, 2012) |
| "1." | 1.37 | Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. ( Chen, HY; Gao, X; Li, XM; Ling, Y; Liu, Y; Lu, DR; Lu, ZQ; Yi, QL, 2011) |
| "Metabolic syndrome was defined according to ATPIII criteria." | 1.36 | Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants. ( Agostinelli, L; Boscaro, M; Di Mattia, D; Giacchetti, G; Rilli, S; Ronconi, V; Turchi, F, 2010) |
| "The aldosterone level was comparable in both groups." | 1.35 | Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families. ( Poredos, P; Trojar, A; Zeljko, T; Zizek, B, 2008) |
| "Essential hypertension is a disease multifactorially triggered by genetic and environmental factors." | 1.34 | Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007) |
| "Aldosterone is a risk factor for stroke, and the literature suggests it may play a role in increasing the expression of the receptor for EGF (EGFR)." | 1.31 | Spironolactone reduces cerebral infarct size and EGF-receptor mRNA in stroke-prone rats. ( Dorrance, AM; Grekin, R; Osborn, HL; Webb, RC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (4.62) | 18.2507 |
| 2000's | 25 (38.46) | 29.6817 |
| 2010's | 33 (50.77) | 24.3611 |
| 2020's | 4 (6.15) | 2.80 |
| Authors | Studies |
|---|---|
| Boulkroun, S | 2 |
| Fernandes-Rosa, FL | 2 |
| Zennaro, MC | 2 |
| Sydorchuk, L | 1 |
| Dzhuryak, V | 1 |
| Sydorchuk, A | 1 |
| Levytska, S | 1 |
| Petrynych, V | 1 |
| Knut, R | 1 |
| Kshanovska, A | 1 |
| Iftoda, O | 1 |
| Tkachuk, O | 1 |
| Kyfiak, P | 1 |
| Popovich, A | 1 |
| Khomko, O | 1 |
| Sydorchuk, R | 1 |
| Stone, IB | 1 |
| Green, JAEM | 1 |
| Koefoed, AW | 1 |
| Hornik, ES | 1 |
| Williams, JS | 1 |
| Adler, GK | 2 |
| Williams, GH | 3 |
| Dutta, RK | 2 |
| Larsson, M | 1 |
| Arnesen, T | 1 |
| Heie, A | 1 |
| Walz, M | 1 |
| Alesina, P | 1 |
| Gimm, O | 2 |
| Söderkvist, P | 2 |
| Armanini, D | 2 |
| Andrisani, A | 1 |
| Donà, G | 1 |
| Bordin, L | 1 |
| Ambrosini, G | 1 |
| Sabbadin, C | 2 |
| Zheng, FF | 1 |
| Zhu, LM | 1 |
| Zhou, WL | 1 |
| Zhang, Y | 1 |
| Li, MY | 1 |
| Zhu, YC | 1 |
| Wang, JG | 1 |
| Zhu, DL | 1 |
| Gao, PJ | 1 |
| Scholl, UI | 1 |
| Hellman, P | 1 |
| Björklund, P | 1 |
| Åkerström, T | 1 |
| Nanba, K | 1 |
| Omata, K | 1 |
| Gomez-Sanchez, CE | 2 |
| Stratakis, CA | 1 |
| Demidowich, AP | 1 |
| Suzuki, M | 1 |
| Thompson, LDR | 1 |
| Cohen, DL | 1 |
| Luther, JM | 1 |
| Gellert, L | 1 |
| Vaidya, A | 1 |
| Barletta, JA | 1 |
| Else, T | 1 |
| Giordano, TJ | 1 |
| Tomlins, SA | 1 |
| Rainey, WE | 1 |
| Funder, JW | 2 |
| McGraw, AP | 1 |
| Bagley, J | 1 |
| Chen, WS | 1 |
| Galayda, C | 1 |
| Nickerson, H | 1 |
| Armani, A | 1 |
| Caprio, M | 1 |
| Carmeliet, P | 1 |
| Jaffe, IZ | 1 |
| Shlipak, MG | 1 |
| Day, EC | 1 |
| Orenes-Piñero, E | 1 |
| Hernández-Romero, D | 1 |
| Romero-Aniorte, AI | 1 |
| Martínez, M | 1 |
| García-Honrubia, A | 1 |
| Caballero, L | 1 |
| Garrigos-Gómez, N | 1 |
| Andreu-Cayuelas, JM | 1 |
| González, J | 1 |
| Feliu, E | 1 |
| Climent, V | 1 |
| Nicolás-Ruiz, F | 1 |
| De La Morena, G | 1 |
| Valdés, M | 1 |
| Lip, GY | 1 |
| Marín, F | 1 |
| Fischer, E | 1 |
| Beuschlein, F | 3 |
| Williams, TA | 1 |
| Riester, A | 1 |
| Steichen, O | 1 |
| Strom, TM | 1 |
| Monticone, S | 1 |
| Amar, L | 1 |
| Meatchi, T | 1 |
| Mantero, F | 1 |
| Cicala, MV | 1 |
| Quinkler, M | 1 |
| Fallo, F | 1 |
| Allolio, B | 1 |
| Bernini, G | 1 |
| Maccario, M | 1 |
| Giacchetti, G | 2 |
| Jeunemaitre, X | 3 |
| Mulatero, P | 1 |
| Reincke, M | 2 |
| Verwoert, GC | 1 |
| Hofland, J | 1 |
| Amin, N | 1 |
| Mattace-Raso, FU | 1 |
| Sijbrands, EJ | 1 |
| Hofman, A | 1 |
| van den Meiracker, AH | 1 |
| Uitterlinden, AG | 1 |
| van Duijn, CM | 1 |
| de Jong, FH | 1 |
| Danser, AH | 1 |
| Richards, J | 1 |
| Diaz, AN | 1 |
| Gumz, ML | 1 |
| Johnson, AK | 1 |
| Zhang, Z | 1 |
| Clayton, SC | 1 |
| Beltz, TG | 1 |
| Hurley, SW | 1 |
| Thunhorst, RL | 1 |
| Xue, B | 1 |
| Manichaikul, A | 1 |
| Rich, SS | 1 |
| Allison, MA | 1 |
| Guagliardo, NA | 1 |
| Bayliss, DA | 1 |
| Carey, RM | 2 |
| Barrett, PQ | 1 |
| Perez-Rivas, LG | 1 |
| Rhayem, Y | 1 |
| Sabrautzki, S | 1 |
| Hantel, C | 1 |
| Rathkolb, B | 1 |
| Hrabě de Angelis, M | 1 |
| Spyroglou, A | 1 |
| Jones, ES | 1 |
| Spence, JD | 1 |
| Mcintyre, AD | 1 |
| Nondi, J | 1 |
| Gogo, K | 1 |
| Akintunde, A | 1 |
| Hackam, DG | 1 |
| Rayner, BL | 2 |
| MacKenzie, SM | 2 |
| Freel, EM | 1 |
| Connell, JM | 2 |
| Fraser, R | 3 |
| Davies, E | 2 |
| Escher, G | 1 |
| Cristiano, M | 1 |
| Causevic, M | 1 |
| Baumann, M | 1 |
| Frey, FJ | 1 |
| Surbek, D | 1 |
| Mohaupt, MG | 1 |
| Kidambi, S | 1 |
| Kotchen, JM | 1 |
| Krishnaswami, S | 1 |
| Grim, CE | 2 |
| Kotchen, TA | 1 |
| Ronconi, V | 1 |
| Turchi, F | 1 |
| Rilli, S | 1 |
| Di Mattia, D | 1 |
| Agostinelli, L | 1 |
| Boscaro, M | 1 |
| Nejatizadeh, A | 2 |
| Kumar, R | 3 |
| Stobdan, T | 1 |
| Goyal, AK | 1 |
| Gupta, M | 2 |
| Tyagi, S | 2 |
| Jain, SK | 2 |
| Pasha, MA | 2 |
| Tomaschitz, A | 1 |
| Pilz, S | 1 |
| Ritz, E | 1 |
| Obermayer-Pietsch, B | 1 |
| Pieber, TR | 1 |
| Gomez-Sanchez, EP | 1 |
| Cheng, X | 1 |
| Xu, G | 1 |
| Wang, B | 1 |
| Zhang, G | 1 |
| Ouyang, J | 1 |
| Deng, X | 1 |
| Shi, T | 1 |
| Ma, X | 1 |
| Li, H | 1 |
| Ju, Z | 1 |
| Wang, C | 1 |
| Wu, Z | 1 |
| Liu, S | 1 |
| Zhang, X | 1 |
| Somekh, NN | 1 |
| Finkielstein, D | 1 |
| Hiura, Y | 1 |
| Tabara, Y | 1 |
| Kokubo, Y | 1 |
| Okamura, T | 1 |
| Miki, T | 1 |
| Tomoike, H | 1 |
| Iwai, N | 1 |
| Brown, MB | 1 |
| Haack, KK | 1 |
| Pollack, BP | 1 |
| Millard-Stafford, M | 1 |
| McCarty, NA | 1 |
| Li, XM | 1 |
| Ling, Y | 1 |
| Lu, DR | 1 |
| Lu, ZQ | 1 |
| Yi, QL | 1 |
| Liu, Y | 1 |
| Chen, HY | 1 |
| Gao, X | 1 |
| Markan, A | 1 |
| Azizan, EA | 1 |
| Murthy, M | 1 |
| Stowasser, M | 1 |
| Gordon, R | 1 |
| Kowalski, B | 1 |
| Xu, S | 1 |
| Brown, MJ | 1 |
| O'Shaughnessy, KM | 1 |
| Schoeffel, CD | 1 |
| Gildea, JJ | 1 |
| Jones, JE | 1 |
| McGrath, HE | 1 |
| Gordon, LN | 1 |
| Park, MJ | 1 |
| Sobota, RS | 1 |
| Underwood, PC | 1 |
| Williams, J | 1 |
| Sun, B | 1 |
| Raby, B | 1 |
| Lasky-Su, J | 1 |
| Hopkins, PN | 2 |
| Williams, SM | 1 |
| Jose, PA | 1 |
| Felder, RA | 1 |
| Pratt, JH | 2 |
| Ambrosius, WT | 2 |
| Agarwal, R | 1 |
| Eckert, GJ | 1 |
| Newman, S | 1 |
| Persu, A | 1 |
| Owen, EP | 1 |
| King, JA | 1 |
| Soule, SG | 1 |
| Vreede, H | 1 |
| Opie, LH | 1 |
| Marais, D | 1 |
| Davidson, JS | 1 |
| Qadar Pasha, MA | 1 |
| Khan, AP | 1 |
| Gupta, V | 1 |
| Grover, SK | 1 |
| Norboo, T | 1 |
| Srivastava, KK | 1 |
| Selvamurthy, W | 1 |
| Brahamchari, SK | 1 |
| Okano, H | 1 |
| Ohkubo, C | 1 |
| Kosachunhanun, N | 1 |
| Hunt, SC | 1 |
| Williams, RR | 1 |
| Corvol, P | 2 |
| Ferri, C | 1 |
| Mortensen, RM | 1 |
| Hollenberg, NK | 1 |
| El-Atat, F | 1 |
| Aneja, A | 1 |
| Mcfarlane, S | 1 |
| Sowers, J | 1 |
| Schächinger, H | 1 |
| Dieterle, T | 1 |
| Martina, B | 1 |
| Haberthür, C | 1 |
| Huber, PR | 1 |
| Bock, A | 1 |
| Drewe, J | 1 |
| Gyr, K | 1 |
| Friel, EC | 1 |
| Ingram, MC | 1 |
| Holloway, CD | 1 |
| Kamide, K | 1 |
| Tanaka, C | 1 |
| Takiuchi, S | 1 |
| Miwa, Y | 1 |
| Yoshii, M | 1 |
| Horio, T | 1 |
| Kawano, Y | 1 |
| Miyata, T | 1 |
| Hannila-Handelberg, T | 1 |
| Kontula, K | 1 |
| Tikkanen, I | 1 |
| Tikkanen, T | 1 |
| Fyhrquist, F | 1 |
| Helin, K | 1 |
| Fodstad, H | 1 |
| Piippo, K | 1 |
| Miettinen, HE | 1 |
| Virtamo, J | 1 |
| Krusius, T | 1 |
| Sarna, S | 1 |
| Gautschi, I | 1 |
| Schild, L | 1 |
| Hiltunen, TP | 1 |
| Achard, JM | 1 |
| Hadchouel, J | 1 |
| Faure, S | 1 |
| Sookoian, S | 1 |
| Gianotti, TF | 1 |
| González, CD | 1 |
| Pirola, CJ | 1 |
| Rosskopf, D | 1 |
| Schürks, M | 1 |
| Rimmbach, C | 1 |
| Schäfers, R | 1 |
| Freitas, SR | 1 |
| Cabello, PH | 1 |
| Moura-Neto, RS | 1 |
| Dolinsky, LC | 1 |
| Lima, AB | 1 |
| Barros, M | 1 |
| Bittencourt, I | 1 |
| Cordovil, IL | 1 |
| Zizek, B | 1 |
| Poredos, P | 1 |
| Trojar, A | 1 |
| Zeljko, T | 1 |
| Harrap, SB | 1 |
| Davidson, HR | 1 |
| Connor, JM | 1 |
| Soubrier, F | 1 |
| Foy, CJ | 1 |
| Watt, GC | 1 |
| MacLeod, AB | 1 |
| Vasdev, S | 1 |
| Smeda, JS | 1 |
| Hautanen, A | 1 |
| Toivanen, P | 1 |
| Mänttäri, M | 1 |
| Tenkanen, L | 1 |
| Kupari, M | 1 |
| Manninen, V | 1 |
| Kayes, KM | 1 |
| Rosenfeld, S | 1 |
| White, PC | 1 |
| Wagner, MA | 1 |
| Maharry, K | 1 |
| Poch, E | 1 |
| González, D | 1 |
| de la Sierra, A | 1 |
| Giner, V | 1 |
| Bragulat, E | 1 |
| Botey, A | 1 |
| Coca, A | 1 |
| Rivera, F | 1 |
| Takeda, Y | 1 |
| Yoneda, T | 1 |
| Demura, M | 1 |
| Furukawa, K | 1 |
| Miyamori, I | 1 |
| Mabuchi, H | 1 |
| Dorrance, AM | 1 |
| Osborn, HL | 1 |
| Grekin, R | 1 |
| Webb, RC | 1 |
| Campese, VM | 1 |
| Lasseter, KC | 1 |
| Ferrario, CM | 1 |
| Smith, WB | 1 |
| Ruddy, MC | 1 |
| Smith, RD | 1 |
| Vargas, R | 1 |
| Habashy, MF | 1 |
| Vesterqvist, O | 1 |
| Delaney, CL | 1 |
| Liao, WC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055] | Phase 4 | 75 participants (Anticipated) | Interventional | 2023-08-25 | Recruiting | ||
| Salt Sensitive Hypertension and Striatin[NCT03683069] | Phase 4 | 400 participants (Actual) | Interventional | 2019-01-15 | Active, not recruiting | ||
| [NCT00005181] | 0 participants | Observational | 2000-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
18 reviews available for aldosterone and Genetic Predisposition
| Article | Year |
|---|---|
Old and new genes in primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Genetic Association Studies; Genetic | 2020 |
Unanswered Questions in the Genetic Basis of Primary Aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; DNA Copy Num | 2017 |
Primary Aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; beta Catenin; Calcium Channels, L-Typ | 2019 |
Biomarkers for incident CKD: a new framework for interpreting the literature.
Topics: Acute-Phase Proteins; Aldosterone; Biomarkers; Connective Tissue Growth Factor; Creatinine; Cystatin | 2013 |
Novel genes in primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Calcium Channels, L-Type; Female; G P | 2014 |
Expression and gene variation studies deny association of human HSD3B1 gene with aldosterone production or blood pressure.
Topics: Adrenal Cortex; Aged; Aldosterone; Blood Pressure; Cells, Cultured; Female; Gene Expression Regulati | 2015 |
Clock genes in hypertension: novel insights from rodent models.
Topics: Aldosterone; Animals; ARNTL Transcription Factors; Blood Vessels; Circadian Rhythm; CLOCK Proteins; | 2014 |
The roles of sensitization and neuroplasticity in the long-term regulation of blood pressure and hypertension.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular Syst | 2015 |
Syndromes that Mimic an Excess of Mineralocorticoids.
Topics: Aldosterone; Biomarkers; Cushing Syndrome; Dexamethasone; Diet; Genetic Predisposition to Disease; G | 2016 |
Genetics of primary hyperaldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Animals; Genetic Pred | 2016 |
ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Genetic | 2017 |
Aldosterone and arterial hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Brain; Cytochrome P-45 | 2010 |
A systemic review of the relationship between aldosterone synthase - 344 C/T polymorphism and hypertension in Han.
Topics: Aldosterone; China; Female; Genetic Predisposition to Disease; Humans; Hypertension; Male; Polymorph | 2010 |
Obesity and hypertension.
Topics: Adipose Tissue; Aldosterone; Body Mass Index; Cardiovascular System; Genetic Predisposition to Disea | 2003 |
The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Cortodoxone; Cytochrome P-450 CYP11B2; Gen | 2004 |
Inherited sodium avid states.
Topics: Aldosterone; Genetic Predisposition to Disease; Humans; Hypertension; Nephrons; Renin; Sodium; Sodiu | 2006 |
Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis.
Topics: Aldosterone; Blood Pressure; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Cytochro | 2007 |
Genetics of arterial hypertension and hypotension.
Topics: Aldosterone; Blood Pressure; Genetic Predisposition to Disease; Humans; Hydrocortisone; Hypertension | 2007 |
6 trials available for aldosterone and Genetic Predisposition
| Article | Year |
|---|---|
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.
Topics: Adult; Aldosterone; Blood Pressure; Body Mass Index; Diet; Dose-Response Relationship, Drug; Female; | 2012 |
Racial difference in the activity of the amiloride-sensitive epithelial sodium channel.
Topics: Adolescent; Adult; Aldosterone; Amiloride; Black People; Blood Pressure; Body Mass Index; Cohort Stu | 2002 |
Genetic factors associated with volume-sensitive hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Blood Volume; Calmodulin-Binding Proteins | 2004 |
Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction.
Topics: Adult; Aldosterone; Alleles; Baroreflex; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; C | 1999 |
Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood | 2001 |
41 other studies available for aldosterone and Genetic Predisposition
| Article | Year |
|---|---|
The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Case-Control Studies; Cytochrome P-450 CYP11B2; Diabetes M | 2020 |
X-chromosome variants are associated with aldosterone producing adenomas.
Topics: Adenoma; Aldosterone; Carrier Proteins; Case-Control Studies; Chromosomes, Human, X; Cohort Studies; | 2021 |
Hypothesis on a relationship between hyperaldosteronism, inflammation, somatic mutations, and autoimmunity.
Topics: Aldosterone; Autoimmunity; Desoxycorticosterone; Genetic Predisposition to Disease; Humans; Hyperald | 2017 |
A novel somatic mutation 145-147delETEinsK in KCNJ5 increases aldosterone production.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Biomarkers, Tumor; Calcium; Female; G | 2017 |
Aldosterone-Producing Adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Genetic Predisposition to Disease; Hu | 2019 |
Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Black or African Amer | 2019 |
Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.
Topics: Aldosterone; Animals; Aorta, Abdominal; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Chemoki | 2013 |
Prognostic value of two polymorphisms in non-sarcomeric genes for the development of atrial fibrillation in patients with hypertrophic cardiomyopathy.
Topics: Adult; Aged; Aldosterone; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Case-Control Studies; C | 2014 |
Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Age Factors; Aldosterone; Calcium Channels, | 2014 |
KCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; California; Ethnicity; Female; Genetic Pr | 2016 |
Genetic characterization of a mouse line with primary aldosteronism.
Topics: Aldosterone; Animals; Biomarkers; Disease Models, Animal; Exome; Female; Genetic Association Studies | 2017 |
High Frequency of Variants of Candidate Genes in Black Africans with Low Renin-Resistant Hypertension.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Cytochrome P-450 | 2017 |
High aldosterone-to-renin variants of CYP11B2 and pregnancy outcome.
Topics: Adult; Aldosterone; Base Sequence; Blood Pressure; Case-Control Studies; Cytochrome P-450 CYP11B2; D | 2009 |
Hypertension, insulin resistance, and aldosterone: sex-specific relationships.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Anthropometry; Black or African American; Blood Glucose | 2009 |
Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants.
Topics: Adiponectin; Aldosterone; Biomarkers; Blood Glucose; Chi-Square Distribution; Cross-Sectional Studie | 2010 |
CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension.
Topics: Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2; Genetic Predisposition to Disease; Haplotypes; H | 2010 |
Aldosterone-producing adenomas: mining for genes.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Genetic Predisposition to Disease; Genetic T | 2010 |
Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; China; Cytochro | 2010 |
A mother/daughter case of familial hyperaldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Biomarkers; Blo | 2010 |
A genome-wide association study of hypertension-related phenotypes in a Japanese population.
Topics: Adult; Aged; Alcohol Drinking; Aldosterone; Asian People; Biomarkers; Blood Pressure; Body Mass Inde | 2010 |
Low abundance of sweat duct Cl- channel CFTR in both healthy and cystic fibrosis athletes with exceptionally salty sweat during exercise.
Topics: Adult; Aldosterone; Aquaporin 5; Bicycling; Biopsy; Case-Control Studies; Cystic Fibrosis; Cystic Fi | 2011 |
Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population.
Topics: Aldosterone; Asian People; Blood Glucose; Blood Pressure; Case-Control Studies; China; Cytochrome P- | 2011 |
The epistasis between vascular homeostasis genes is apparent in essential hypertension.
Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Case-Control Studies; Chi-Square Distribut | 2012 |
Somatic mutations affecting the selectivity filter of KCNJ5 are frequent in 2 large unselected collections of adrenal aldosteronomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; DNA, Neoplasm; Female; G Protein-Coup | 2012 |
The epithelial Na+ channel: progressing from Liddle's syndrome to essential hypertension.
Topics: Aldosterone; Black People; Disease Progression; Genetic Predisposition to Disease; Humans; Hypertens | 2003 |
A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.
Topics: Adult; Aged; Aldosterone; Amino Acid Sequence; Biomarkers; Black People; Female; Genetic Predisposit | 2003 |
Association of high-altitude systemic hypertension with the deletion allele-of the angiotensin-converting enzyme (ACE) gene.
Topics: Adaptation, Physiological; Adult; Aldosterone; Altitude; Case-Control Studies; Gene Deletion; Geneti | 2003 |
Effects of static magnetic fields on plasma levels of angiotensin II and aldosterone associated with arterial blood pressure in genetically hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electro | 2003 |
Genetic determinants of nonmodulating hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Epistasis, Genetic; Family Health; Female | 2003 |
Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers | 2004 |
Six missense mutations of the epithelial sodium channel beta and gamma subunits in Japanese hypertensives.
Topics: Aged; Aldosterone; Asian People; Epithelial Sodium Channels; Exons; Female; Genetic Predisposition t | 2004 |
Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension.
Topics: Adult; Aged; Aldosterone; Alleles; Epithelial Sodium Channels; Female; Genetic Predisposition to Dis | 2005 |
Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension.
Topics: Aldosterone; Brazil; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease | 2007 |
Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families.
Topics: Adult; Aldosterone; Case-Control Studies; Female; Genetic Predisposition to Disease; Heart Failure, | 2008 |
Translational research goes both ways: lessons from clinical studies.
Topics: Aldosterone; Amino Acid Sequence; Antihypertensive Agents; Biomedical Research; Clinical Trials as T | 2008 |
The angiotensin I converting enzyme gene and predisposition to high blood pressure.
Topics: Adult; Aldosterone; Alleles; Angiotensin II; Blood Pressure; Diastole; Family; Female; Genetic Predi | 1993 |
The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cerebral | 1997 |
Molecular variations in the calcium-sensing receptor in relation to sodium balance and presence of hypertension in blacks and whites.
Topics: Adolescent; Adult; Aldosterone; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; | 2000 |
Genetic variation of the gamma subunit of the epithelial Na+ channel and essential hypertension. Relationship with salt sensitivity.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; DNA; DNA Primers; Epithel | 2000 |
Effects of high sodium intake on cardiovascular aldosterone synthesis in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Cardiovascular System; Diet; Genetic Predisposition to Disease; Hypertension; | 2001 |
Spironolactone reduces cerebral infarct size and EGF-receptor mRNA in stroke-prone rats.
Topics: Aldosterone; Animals; Aorta; Basal Ganglia; Blood Pressure; Body Weight; Cerebral Cortex; Cerebral I | 2001 |