aldosterone has been researched along with Focal Segmental Glomerulosclerosis in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aldosterone has pro-fibrotic properties and is a potential target for additional intervention in patients with chronic renal disease showing resistance to therapy during treatment with angiotensin-converting enzyme inhibitors (ACEi)." | 5.34 | Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis. ( Hamming, I; Kramer, AB; Navis, G; van der Meulen, EF; van Goor, H, 2007) |
| "Treatment with rotenone, an inhibitor of mitochondrial complex I, significantly attenuated oxidative stress, mitochondrial dysfunction, and inflammasome response in aldosterone-infused rats." | 1.42 | Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation. ( Ding, W; Wang, B; Xu, C; Zhang, M, 2015) |
| "Aldosterone has pro-fibrotic properties and is a potential target for additional intervention in patients with chronic renal disease showing resistance to therapy during treatment with angiotensin-converting enzyme inhibitors (ACEi)." | 1.34 | Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis. ( Hamming, I; Kramer, AB; Navis, G; van der Meulen, EF; van Goor, H, 2007) |
| "Aldosterone promotes nephrosclerosis in several rat models, whereas aldosterone receptor antagonism blunts the effect of activation of the renin-angiotensin-aldosterone system (RAAS) on nephrosclerosis, independent of effects on blood pressure." | 1.31 | Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo. ( Brown, NJ; Donnert, E; Fogo, AB; Freeman, M; Ma, L; Nakamura, I; Nakamura, S; Vaughan, DE, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, W | 1 |
| Xu, C | 1 |
| Wang, B | 1 |
| Zhang, M | 1 |
| Manger, WM | 1 |
| Simchon, S | 1 |
| Stokes, MB | 1 |
| Reidy, JJ | 1 |
| Kumar, AR | 1 |
| Baer, L | 1 |
| Gallo, G | 1 |
| Haddy, FJ | 1 |
| Lahmer, T | 1 |
| Hermans, R | 1 |
| Schmaderer, C | 1 |
| Chang, J | 1 |
| Stock, K | 1 |
| Lutz, J | 1 |
| Heemann, U | 1 |
| Baumann, M | 1 |
| Kramer, AB | 1 |
| van der Meulen, EF | 1 |
| Hamming, I | 1 |
| van Goor, H | 1 |
| Navis, G | 1 |
| Peters, B | 1 |
| Grisk, O | 1 |
| Becher, B | 1 |
| Wanka, H | 1 |
| Kuttler, B | 1 |
| Lüdemann, J | 1 |
| Lorenz, G | 1 |
| Rettig, R | 1 |
| Mullins, JJ | 1 |
| Peters, J | 1 |
| Stoian, M | 1 |
| Radulian, G | 1 |
| Chiţac, D | 1 |
| Simion, E | 1 |
| Stoica, V | 1 |
| Geers, AB | 1 |
| Koomans, HA | 1 |
| Roos, JC | 1 |
| Boer, P | 1 |
| Dorhout Mees, EJ | 1 |
| Stalnikowicz, R | 1 |
| Shalev, O | 1 |
| Rosenmann, E | 1 |
| Ben-Ishay, D | 1 |
| Brown, NJ | 1 |
| Nakamura, S | 1 |
| Ma, L | 2 |
| Nakamura, I | 1 |
| Donnert, E | 1 |
| Freeman, M | 1 |
| Vaughan, DE | 1 |
| Fogo, AB | 2 |
| Swainson, CP | 1 |
| Nicholls, MG | 1 |
| Espiner, EA | 1 |
| Nakamoto, Y | 1 |
| Imai, H | 1 |
| Hamanaka, S | 1 |
| Yoshida, K | 1 |
| Akihama, T | 1 |
| Miura, AB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Crossover Pilot Study of the Effect of Amiloride on Proteinuria in Patients With Proteinuric Kidney Disease[NCT02522650] | Phase 4 | 30 participants (Anticipated) | Interventional | 2013-07-31 | Recruiting | ||
| [NCT00005757] | 293 participants (Actual) | Observational | 1997-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aldosterone and Focal Segmental Glomerulosclerosis
| Article | Year |
|---|---|
A clinical approach in regression of glomerulosclerosis.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2007 |
Role of angiotensin II in glomerular injury.
Topics: Aldosterone; Angiotensin II; Animals; Glomerulosclerosis, Focal Segmental; Humans; Kidney Glomerulus | 2001 |
10 other studies available for aldosterone and Focal Segmental Glomerulosclerosis
| Article | Year |
|---|---|
Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Carrier Proteins; DNA, Mitochondrial; Glomeruloscleros | 2015 |
Renal functional, not morphological, abnormalities account for salt sensitivity in Dahl rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Diastole; Dose-Response Relationsh | 2009 |
Mineralocorticoid receptor antagonism and aldosterone synthesis inhibition do not improve glomerulosclerosis and renal interstitial fibrosis in a model of chronic kidney allograft injury.
Topics: Aldosterone; Animals; Disease Models, Animal; Extracellular Fluid; Fibrosis; Glomerulosclerosis, Foc | 2012 |
Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis.
Topics: Actins; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Blood Pressure; | 2007 |
Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis.
Topics: Administration, Oral; Aldosterone; Animals; Animals, Genetically Modified; Blood Pressure; Cytochrom | 2008 |
Functional relationships in the nephrotic syndrome.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Blood Volume; Creatinine; Diet, Sodium-Restric | 1984 |
Hyporeninemic hypoaldosteronism associated with focal glomerular sclerosis in a patient with chronic lymphocytic leukemia.
Topics: Aged; Aldosterone; Fludrocortisone; Furosemide; Glomerulonephritis; Glomerulosclerosis, Focal Segmen | 1982 |
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blotting, Northern; Creatinine; Disease Progre | 2000 |
No evidence of failure of the renin-angiotensin system in focal glomerulosclerosis in man.
Topics: Aldosterone; Blood Pressure; Female; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Humans | 1986 |
IgM monoclonal gammopathy accompanied by nodular glomerulosclerosis, urine-concentrating defect, and hyporeninemic hypoaldosteronism.
Topics: Aldosterone; Biopsy; Cyclophosphamide; Drug Therapy, Combination; Fluorescent Antibody Technique; Gl | 1985 |