Page last updated: 2024-11-07

aldosterone and Fasting Hypoglycemia

aldosterone has been researched along with Fasting Hypoglycemia in 41 studies

Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.

Research Excerpts

ExcerptRelevanceReference
"Treatment with bromocriptine resulted in a significant fall of systolic and diastolic blood pressure in supine and upright position accompanied by a marked reduction in plasma and urinary noradrenaline but without effect on adrenaline."5.26Effect of the dopamine agonist bromocriptine on blood pressure, catecholamines and renin activity in acromegalics at rest, following exercise and during insulin induced hypoglycemia. ( Hökfelt, B; Nilsson, A, 1978)
"Over 80% of Addison's disease is of the autoimmune type, though almost any systemic destructive process can cause similar steroid insufficiency."2.37Adrenocortical insufficiency. ( Burke, CW, 1985)
"Essential hypertension is associated with changes in central catecholaminergic pathways which might also be reflected in the pituitary response to stress stimuli."1.33Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertension. ( Cizmarova, E; Huckova, M; Koska, J; Kvetnansky, R; Penesova, A; Radikova, Z; Vigas, M, 2006)
" Thereafter, the dosage of cortisol was reduced to induce plasma values similar to normal late-gestation cortisol concentration in ewes (1 mg/kg per day), or to values in nonpregnant ewes (0."1.30Sheep model for study of maternal adrenal gland function during pregnancy. ( Caldwell, SM; Cudd, TA; Keller-Wood, M; Norman, W; Wood, CE, 1998)
"Aldosterone excretion was markedly reduced (0."1.26Adrenocorticotropin deficiency: correction of hyponatremia and hypoaldosteronism with chronic glucocorticoid therapy. ( Baer, L; Merriam, GR, 1980)
"Treatment with bromocriptine resulted in a significant fall of systolic and diastolic blood pressure in supine and upright position accompanied by a marked reduction in plasma and urinary noradrenaline but without effect on adrenaline."1.26Effect of the dopamine agonist bromocriptine on blood pressure, catecholamines and renin activity in acromegalics at rest, following exercise and during insulin induced hypoglycemia. ( Hökfelt, B; Nilsson, A, 1978)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199030 (73.17)18.7374
1990's3 (7.32)18.2507
2000's3 (7.32)29.6817
2010's3 (7.32)24.3611
2020's2 (4.88)2.80

Authors

AuthorsStudies
Kamenický, P1
Blanchard, A1
Lamaziere, A1
Piedvache, C1
Donadille, B1
Duranteau, L1
Bry, H1
Gautier, JF1
Salenave, S1
Raffin-Sanson, ML1
Genc, S1
Pietri, L1
Christin-Maitre, S1
Thomas, J1
Lorthioir, A1
Azizi, M1
Chanson, P1
Le Bouc, Y1
Brailly-Tabard, S1
Young, J1
Wils, J1
Duparc, C1
Cailleux, AF1
Lopez, AG1
Guiheneuf, C1
Boutelet, I1
Boyer, HG1
Dubessy, C1
Cherifi, S1
Cauliez, B1
Gobet, F1
Defortescu, G1
Ménard, JF1
Louiset, E1
Lefebvre, H1
Varga, J2
Ferenczi, S2
Kovács, KJ2
Garafova, A1
Jezova, D2
Zelena, D2
Csáno, Á1
Prokopova, B1
Adler, GK1
Bonyhay, I1
Curren, V1
Waring, E1
Freeman, R1
BERTHAUX, P1
RAVERA, JJ1
EYMONTT, MJ1
GWINUP, G1
KRUGER, FA1
MAYNARD, DE1
HAMWI, GJ1
Radikova, Z1
Penesova, A1
Cizmarova, E1
Huckova, M1
Kvetnansky, R1
Vigas, M1
Koska, J1
Lam, YY1
Lo, IF1
Shek, CC1
Tong, TM1
Ng, DK1
Tong, TF1
Choi, MS1
Lam, ST1
Ho, CS1
Huang, DY1
Boini, KM1
Osswald, H1
Friedrich, B1
Artunc, F1
Ullrich, S1
Rajamanickam, J1
Palmada, M1
Wulff, P1
Kuhl, D1
Vallon, V1
Lang, F1
Frier, BM1
Al-Dujaili, EA1
Corrall, RJ1
Pritchard, JL1
Edwards, CR1
Merriam, GR1
Baer, L1
Geffner, ME1
Lippe, BM1
Kaplan, SA1
Itami, RM1
Hochberg, Z1
Dickerman, Z1
Kaufman, H1
Laron, Z1
Hughes, IA1
Davies, PA1
Turinsky, J1
Loegering, DL1
Patterson, SA1
Shangraw, RE1
Lipinski, TL1
Wong, PY1
Mazzocchi, G1
Malendowicz, LK1
Gottardo, G1
Meneghelli, V1
Nussdorfer, GG1
Guivarc'h-Lévêque, A1
Vovan, JM1
Le Bervet, JY1
Broux, PL1
Giraud, JR1
Keller-Wood, M2
Cudd, TA1
Norman, W1
Caldwell, SM1
Wood, CE1
Moreau, L1
Servant, A1
Valcke, J1
Hata, S1
Kunita, H1
Okamoto, M1
Nilsson, A1
Hökfelt, B2
Ishimaru, K1
Saito, H1
Oshima, I1
Saito, S1
Susaki, S1
Matsuda, M1
Mori, H1
Pimstone, B1
Jungmann, E1
Konzok, C1
Höll, E1
Fassbinder, W1
Schöffling, K1
Guthrie, GP1
Kotchen, TA1
Van Loon, GR1
Trovati, M1
Massucco, P1
Cavalot, F1
Anfossi, G1
Mularoni, E1
Busca, G1
Orecchia, C1
Emanuelli, G1
Burke, CW1
Kimura, B1
Phillips, MI1
Bianchi, C1
di Natale, B1
Trifirò, G1
Weber, G1
Słowińska-Srzednicka, J1
Zgliczyński, S1
Lundberg, D1
Weille, FL1
Grant, JK1
Hall, PE1
Kershnar, AK1
Roe, TF1
Kogut, MD1
Vieweg, WV1
Reitz, RE1
Weinstein, RL1
Krieger, DT1
Hedeland, H1
Dymling, JF1
Ehrlich, RM1
Kooh, SW1
Klevit, HD1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Adrenocortical Functions by Insulin Tolerance Test and Sodium Depletion in Women With Nonclassical Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency in Comparison With Healthy Volunteers.[NCT01862380]41 participants (Actual)Interventional2013-02-28Active, not recruiting
Pilot Study of the Action of the Substance P Antagonist Aprepitant on Aldosterone and Cortisol Secretion in Healthy Volunteers.[NCT00977223]Phase 420 participants (Actual)Interventional2009-06-30Completed
Hypoglycemia and Autonomic Nervous System Function[NCT01816893]22 participants (Actual)Interventional2004-06-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Catecholamine Response to Lower-body Negative Pressure

Plasma norepinephrine response to lower body negative pressure (at the minus 40 mm Hg data point) on Day 3 about 16 to 20 hours after completion of the euglycemic or hypoglycemic clamp. (NCT01816893)
Timeframe: 16 hours after euglycemic and hypoglycemic clamps

Interventionnmol/L (Mean)
Euglycemic Clamp3.0
Hypoglycemic Clamp2.0

Change in Baroreflex Sensitivity

The change in baroreflex sensitivity (milliseconds/mm Hg) is calculated as baroreflex sensitivity (milliseconds/mm Hg) on day 3 [assessed 16 hours after the clamp] minus baroreflex sensitivity (milliseconds/mm Hg) on day 1 [baseline assessment on the day prior to the clamp]). Change in baroreflex sensitivity in euglycemic clamp arm is compared to change in baroreflex sensitivity in hypoglycemic arm. (NCT01816893)
Timeframe: 16 hours after euglycemic and hypoglycemic clamps as compared to baseline

Interventionms/mmHg (Mean)
Euglycemic Clamp2.3
Hypoglycemic Clamp-1.6

Muscle Sympathetic Nerve Activity

Muscle sympathetic nerve activity (MSNA), at rest and immediately after nitroprusside, was measured on Day 3 about 16 hours after the euglycemic and hypoglycemic clamps. (NCT01816893)
Timeframe: 16 hours after euglycemic and hypoglycemic clamps

,
Interventionbursts/ minute (Mean)
At restWith Nitroprusside
Euglycemic Clamp33.6453.4
Hypoglycemic Clamp26.440.1

Reviews

6 reviews available for aldosterone and Fasting Hypoglycemia

ArticleYear
[PROGRESS IN ENDOCRINOLOGY].
    Prensa medica argentina, 1963, May-10, Volume: 50

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Aldosterone; Cholesterol; Chromosome Aberrations; E

1963
Neonatal endocrine and metabolic emergencies.
    Clinics in endocrinology and metabolism, 1980, Volume: 9, Issue:3

    Topics: Adrenal Insufficiency; Aldosterone; Disorders of Sex Development; Emergencies; Female; Humans; Hyper

1980
[Anterior antehypaphyseal insufficiecency in the elderly].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1975, Jan-08, Volume: 51, Issue:2

    Topics: Aged; Aging; Aldosterone; Anemia; Arteriosclerosis; Autoantibodies; Autoimmune Diseases; Coma; Femal

1975
Endocrine function in protein-calorie malnutrition.
    Clinical endocrinology, 1976, Volume: 5, Issue:1

    Topics: Adrenal Medulla; Aldosterone; Amino Acids; Basal Metabolism; Bone Development; Follicle Stimulating

1976
Adrenocortical insufficiency.
    Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:4

    Topics: Addison Disease; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; A

1985
Laboratory investigation of the human hypothalamic-pituitary-adrenocortical system.
    Scottish medical journal, 1971, Volume: 16, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adre

1971

Trials

2 trials available for aldosterone and Fasting Hypoglycemia

ArticleYear
The neuropeptide substance P regulates aldosterone secretion in human adrenals.
    Nature communications, 2020, 05-29, Volume: 11, Issue:1

    Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Aprepitant; Cells, Cultured; Humans;

2020
Effect of human atrial natriuretic peptide on blood glucose concentrations and hormone stimulation during insulin-induced hypoglycaemia in healthy man.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Glucose; Double-Bl

1989

Other Studies

33 other studies available for aldosterone and Fasting Hypoglycemia

ArticleYear
Cortisol and Aldosterone Responses to Hypoglycemia and Na Depletion in Women With Non-Classic 21-Hydroxylase Deficiency.
    The Journal of clinical endocrinology and metabolism, 2020, 01-01, Volume: 105, Issue:1

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Biomarkers; Case-Control Studies; E

2020
Comparison of stress-induced changes in adults and pups: is aldosterone the main adrenocortical stress hormone during the perinatal period in rats?
    PloS one, 2013, Volume: 8, Issue:9

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Co

2013
Dissociation of adrenocorticotropin and corticosterone as well as aldosterone secretion during stress of hypoglycemia in vasopressin-deficient rats.
    Life sciences, 2016, Dec-01, Volume: 166

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Gene Deletion; Hypoglycemia; Male

2016
Hypoglycaemia increases aldosterone in a dose-dependent fashion.
    Diabetic medicine : a journal of the British Diabetic Association, 2010, Volume: 27, Issue:11

    Topics: Adult; Aldosterone; Blood Glucose; Dose-Response Relationship, Drug; Female; Glucose Clamp Technique

2010
[Critical review of ideas & facts].
    Bulletin medical, 1957, Volume: 71, Issue:11

    Topics: Aldosterone; Diabetes Mellitus; Electrolytes; Enzymes; Glucose Tolerance Test; Gout; Humans; Hypogly

1957
CUSHING'S SYNDROME WITH HYPOGLYCEMIA CAUSED BY ADRENOCORTICAL CARCINOMA.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Aldos

1965
Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertension.
    Journal of human hypertension, 2006, Volume: 20, Issue:7

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Case-Control Studies; Epinephrine; Growth Hormone

2006
Triple-A syndrome--the first Chinese patient with novel mutations in the AAAS gene.
    Journal of pediatric endocrinology & metabolism : JPEM, 2006, Volume: 19, Issue:5

    Topics: Adrenal Cortex Diseases; Adrenal Cortex Function Tests; Aldosterone; China; Epilepsy, Tonic-Clonic;

2006
Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:6

    Topics: Aldosterone; Animal Feed; Animals; Blood Pressure; Body Weight; Dietary Fats; Drinking; Eating; Elec

2006
Autonomic neural control mechanisms and the release of adrenal steroids after hypoglycaemia in man.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16 Suppl 1

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Atropine; Blood Glucose; C

1984
Adrenocorticotropin deficiency: correction of hyponatremia and hypoaldosteronism with chronic glucocorticoid therapy.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Glucose; Dexamethasone; Female; Fludrocortiso

1980
The use of theophylline as an in vivo probe of adrenocortical function.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:1

    Topics: Adrenal Cortex; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Autoimmune D

1982
Evaluation of the renin-aldosterone system during hypo- and hyperglycemia in children and adolescents.
    Hormone research, 1980, Volume: 12, Issue:1

    Topics: Adolescent; Aldosterone; Child; Female; Glucose; Humans; Hyperglycemia; Hypoglycemia; Insulin; Male;

1980
Energy metabolism of vascular smooth muscle and circulating vasoactive substances in hemorrhagic shock in the dog.
    Circulatory shock, 1980, Volume: 7, Issue:4

    Topics: Acidosis; Aldosterone; Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Bradykinin; Catec

1980
Pancreatic polypeptide enhances plasma glucocorticoid concentration in rats: possible role in hypoglycemic stress.
    Life sciences, 1995, Volume: 56, Issue:8

    Topics: Aldosterone; Animals; Corticosterone; Hypoglycemia; Male; Pancreatic Polypeptide; Rats; Rats, Wistar

1995
[Acute adrenal gland decompensation in the immediate postpartum].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1993, Volume: 22, Issue:8

    Topics: Acute Disease; Adrenal Insufficiency; Adult; Aldosterone; Blood Glucose; Cesarean Section; Coma; Fem

1993
Sheep model for study of maternal adrenal gland function during pregnancy.
    Laboratory animal science, 1998, Volume: 48, Issue:5

    Topics: Adrenal Glands; Adrenal Insufficiency; Adrenalectomy; Aldosterone; Animals; Disease Models, Animal;

1998
Aldosterone response to hypoglycemia: evidence of ACTH mediation.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Depression, Chemical; Humans; Hydro

1976
Effect of the dopamine agonist bromocriptine on blood pressure, catecholamines and renin activity in acromegalics at rest, following exercise and during insulin induced hypoglycemia.
    Acta endocrinologica. Supplementum, 1978, Volume: 216

    Topics: Acromegaly; Aldosterone; Blood Pressure; Bromocriptine; Catecholamines; Dose-Response Relationship,

1978
[Responses of renin-angiotensin-aldosterone system to insulin hypoglycemia in patients with essential hypertension (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:10

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypoglycemia; Insulin; Male;

1978
Effect of transdermal clonidine on the endocrine responses to insulin-induced hypoglycemia in essential hypertension.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:4

    Topics: Administration, Cutaneous; Adult; Aldosterone; Blood Glucose; Blood Pressure; Clonidine; Diabetes Co

1989
Alpha-adrenergic blockade with phentolamine increases the response of the renin-angiotensin-aldosterone system to insulin-induced hypoglycaemia in man.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:5

    Topics: Adult; Aldosterone; Angiotensin I; Blood Glucose; Humans; Hypoglycemia; Insulin; Male; Phentolamine;

1989
Angiotensin II does not alter ACTH responses to hypoglycemia in conscious dogs.
    The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Blood Pr

1987
Isolated glucocorticoid deficiency.
    Journal of endocrinological investigation, 1987, Volume: 10, Issue:6

    Topics: Aldosterone; Diagnosis, Differential; Fasting; Glucocorticoids; Humans; Hypoglycemia; Infant; Male;

1987
Effect of insulin-induced hypoglycemia on plasma renin activity and aldosterone and cortisol concentration in humans.
    Endokrynologia Polska, 1986, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Renin

1986
The pharmacological basis of treatment with high dose corticosteroids in circulatory shock.
    Acta chirurgica Scandinavica. Supplementum, 1985, Volume: 526

    Topics: Adrenal Cortex Hormones; Adult; Aldosterone; Animals; Dexamethasone; Drug Administration Schedule; H

1985
Hypoglycemia in Meniere's disease.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1968, Volume: 87, Issue:5

    Topics: Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Diet Therapy; Dietary Carbohydrates;

1968
Adrenocorticotropic hormone unresponsiveness: report of a girl with excessive growth and review of 16 reported cases.
    The Journal of pediatrics, 1972, Volume: 80, Issue:4

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Arginine; Child; Corticoster

1972
Addison's disease secondary to metastatic carcinoma: an example of adrenocortical and adrenomedullary insuffiency.
    Cancer, 1973, Volume: 31, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adenocarcinoma; Adrenal Glands; Adrenoc

1973
Glandular end organ deficiency associated with secretion of biologically inactive pituitary peptides.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 38, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Biological Assay; Circadian Rhythm; Dexamethasone;

1974
Catecholamines, renin and aldosterone in postural hypotension.
    Acta endocrinologica, 1969, Volume: 62, Issue:3

    Topics: Aldosterone; Catecholamines; Female; Humans; Hypoglycemia; Hypotension, Orthostatic; Insulin; Middle

1969
The use of chlorpropamide in diabetes insipidus in children.
    Pediatrics, 1970, Volume: 45, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adolescent; Aldosterone; Blood Glucose; Child; Child, Preschool; Chlorpro

1970
Corticosteroid therapy in the neonatal period.
    Pediatric clinics of North America, 1970, Volume: 17, Issue:4

    Topics: Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Aldosterone; Communi

1970