aldosterone has been researched along with Edema-Proteinuria-Hypertension Gestosis in 155 studies
Excerpt | Relevance | Reference |
---|---|---|
"To study the relationship between somatostatin (SS), atrial natriuretic peptide (ANP), beta-endorphin (beta-EP), aldosterone (Aldo) and pregnancy induced hypertension (PIH), blood was collected from 69 cases, including non-pregnant women, normal pregnant women, patients with PIH and their newborns (umbilical arteries) and plasma levels of ANP, SS, beta-EP, Aldo were measured by radioimmunoassay." | 7.68 | [Relation between somatostatin, atrial natriuretic peptide, beta-endorphin, aldosterone and pregnancy induced hypertension]. ( Dai, LT, 1993) |
"Plasma concentrations of arginine vasopressin (AVP), angiotensin II (A II), aldosterone (Aldo), serum osmolality (Sosm), urine volume (V), and free water clearance (CH2O) were determined in the third trimester of pregnancy, and 5 days and 3 months after delivery in pre-eclampsia (group I), in normotensive pregnancy (group II), and in non-pregnant control subjects (group III)." | 7.67 | The osmoregulatory system and the renin-angiotensin-aldosterone system in pre-eclampsia and normotensive pregnancy. ( Danielsen, H; Johannesen, P; Pedersen, EB; Rasmussen, AB, 1985) |
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group." | 6.65 | Prostaglandins, renin, aldosterone, and catecholamines in preeclampsia. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1983) |
"Preeclampsia is a hypertensive disorder unique to pregnancy and remains the leading cause of maternal and fetal morbidity and mortality." | 6.44 | Role of aldosterone availability in preeclampsia. ( Escher, G; Mohaupt, M, 2007) |
"Preeclampsia is a life-threatening disorder of pregnancy unique to humans." | 5.72 | Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. ( Dimitriadis, E; Menkhorst, E; Santos, L; St-Pierre, Y; Young, MJ; Zhang, JG; Zhou, W, 2022) |
"Aldosterone levels were not associated to preeclampsia incidence." | 5.51 | Aldosterone, Salt, and Potassium Intakes as Predictors of Pregnancy Outcome, Including Preeclampsia. ( Andersen, LB; Andersen, MS; Birukov, A; Dechend, R; Golic, M; Haase, N; Herse, F; Jensen, BL; Jørgensen, JS; Kitlen, G; Kräker, K; Kyhl, HB; Müller, DN; Rakova, N, 2019) |
"Preeclampsia is associated with alterations in the maternal renin-angiotensin-aldosterone system (RAAS), increased blood pressure (BP), and cardiovascular risk in the offspring." | 5.42 | The renin-angiotensin-aldosterone system in adolescent offspring born prematurely to mothers with preeclampsia. ( Brosnihan, KB; Chappell, MC; Diz, DI; Gwathmey, TM; Nixon, PA; O'Shea, TM; Russell, GB; Snively, BM; Washburn, LK, 2015) |
"However, these values in preeclampsia are decreased to nearly that of a nonpregnant subject, and vascular sensitivity to angiotensin II is increased." | 5.35 | The relationship between aldosterone to renin ratio and RI value of the uterine artery in the preeclamptic patient vs. normal pregnancy. ( Kim, EH; Kim, YH; Lim, JH; Park, YW, 2008) |
"Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified." | 5.31 | The renin-aldosterone system during normal and hypertensive pregnancy. ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001) |
"Furthermore, in preeclampsia, a particularly low ratio seemed to be typical of the patients who showed poorer placental flows and fetal outcomes." | 5.28 | Ratio between aldosterone and atrial natriuretic peptide in pregnancy. ( Canavese, C; Fianchino, O; Gagliardi, L; Gurioli, L; Mattone, GC; Porcu, M; Stratta, P; Todros, T; Vercellone, A, 1989) |
"The aldosterone levels were significantly greater in umbilical veins and artery than in maternal peripheral veins." | 5.28 | [Dopaminergic control of aldosterone and prolactin secretion during normal pregnancy and toxemia of pregnancy]. ( Niibe, T, 1989) |
"Experimental toxemia of pregnancy was induced in 8 pregnant monkeys (Macacamulatta) by reducing the abdomiinal aorta to one-third of its original diameter during the last month of gestation." | 5.26 | Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone. ( Abitbol, MM; Driscoll, SG; Gallo, GR; Ober, MB; Pirani, CL, 1977) |
"2) PRA and PA in toxemia of pregnancy were obviously lower in comparison with normal pregnancy in the corresponding period." | 5.26 | [Renin and aldosterone during pregnancy (author's transl)]. ( Mochizuki, M; Motoyama, S; Tojo, S, 1980) |
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group." | 5.26 | Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1982) |
"To study the relationship between somatostatin (SS), atrial natriuretic peptide (ANP), beta-endorphin (beta-EP), aldosterone (Aldo) and pregnancy induced hypertension (PIH), blood was collected from 69 cases, including non-pregnant women, normal pregnant women, patients with PIH and their newborns (umbilical arteries) and plasma levels of ANP, SS, beta-EP, Aldo were measured by radioimmunoassay." | 3.68 | [Relation between somatostatin, atrial natriuretic peptide, beta-endorphin, aldosterone and pregnancy induced hypertension]. ( Dai, LT, 1993) |
"Plasma concentrations of arginine vasopressin (AVP), angiotensin II (A II), aldosterone (Aldo), serum osmolality (Sosm), urine volume (V), and free water clearance (CH2O) were determined in the third trimester of pregnancy, and 5 days and 3 months after delivery in pre-eclampsia (group I), in normotensive pregnancy (group II), and in non-pregnant control subjects (group III)." | 3.67 | The osmoregulatory system and the renin-angiotensin-aldosterone system in pre-eclampsia and normotensive pregnancy. ( Danielsen, H; Johannesen, P; Pedersen, EB; Rasmussen, AB, 1985) |
"The role of the renin-angiotensin system in the development of hypertension was studied by infusing an angiotensin II analog, 1-Sar, 8-Ile angiotensin II, in women with toxemia and women on estrogen-containing oral contraceptives or estrogen treatment." | 3.66 | Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia. ( Kondo, K; Nagahama, S; Nakamura, R; Saruta, T; Suzuki, H, 1981) |
"Emerging antenatal risk factors such as preeclampsia appear to increase the risk of hypertension and cardiovascular disease across the life course in both the offspring and women after pregnancy." | 3.01 | Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American ( Alexander, BT; August, P; Bertagnolli, M; Ferranti, EP; Grobe, JL; Jones, EJ; Loria, AS; Safdar, B; Sequeira-Lopez, MLS; South, AM, 2023) |
"Superimposed preeclampsia complicates about 20% of pregnancies in women with chronic hypertension and is associated with increased maternal and perinatal morbidity compared with preeclampsia alone." | 2.82 | Chronic hypertension and superimposed preeclampsia: screening and diagnosis. ( Kametas, NA; Nicolaides, KH; Nzelu, D, 2022) |
"Primary aldosteronism (PA) is the most common form of endocrine hypertension." | 2.66 | Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism. ( Gong, S; Meyer, LS; Reincke, M; Williams, TA, 2020) |
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group." | 2.65 | Prostaglandins, renin, aldosterone, and catecholamines in preeclampsia. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1983) |
"Preeclampsia is a hypertensive disorder unique to pregnancy and remains the leading cause of maternal and fetal morbidity and mortality." | 2.44 | Role of aldosterone availability in preeclampsia. ( Escher, G; Mohaupt, M, 2007) |
"Preeclampsia was modeled by transient sFlt1 expression in pregnant mice." | 1.91 | Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia. ( Biwer, LA; Camarda, ND; Carvajal, BV; Ibarrola, J; Jaffe, IZ; Karumanchi, SA; Lu, Q; Man, JJ; Seely, EW; Skurnik, G; Stepanian, A; Zsengeller, Z, 2023) |
"Preeclampsia is a life-threatening disorder of pregnancy unique to humans." | 1.72 | Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. ( Dimitriadis, E; Menkhorst, E; Santos, L; St-Pierre, Y; Young, MJ; Zhang, JG; Zhou, W, 2022) |
"The pathophysiology of preeclampsia (PE) remains unclear." | 1.56 | An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction. ( Chan, HC; Chen, H; Guo, M; Huang, H; Jin, L; Lin, X; Liu, X; Rahman, TU; Ruan, Y; Sheng, J; Tang, L; Ullah, K; Wang, Y; Wu, D; Wu, Y; Xu, G; Yu, P; Yu, Y; Zhou, C, 2020) |
"Aldosterone levels were not associated to preeclampsia incidence." | 1.51 | Aldosterone, Salt, and Potassium Intakes as Predictors of Pregnancy Outcome, Including Preeclampsia. ( Andersen, LB; Andersen, MS; Birukov, A; Dechend, R; Golic, M; Haase, N; Herse, F; Jensen, BL; Jørgensen, JS; Kitlen, G; Kräker, K; Kyhl, HB; Müller, DN; Rakova, N, 2019) |
"We hypothesized that preeclampsia is associated with low prostasin expression in placenta and spillover of prostasin into urine across the defect glomerular barrier." | 1.43 | Prostasin and matriptase (ST14) in placenta from preeclamptic and healthy pregnant women. ( Andersen, LB; Frederiksen-Møller, B; Hansen, MR; Jensen, BL; Jørgensen, JS; Krigslund, O; Vogel, LK, 2016) |
"Preeclampsia is associated with alterations in the maternal renin-angiotensin-aldosterone system (RAAS), increased blood pressure (BP), and cardiovascular risk in the offspring." | 1.42 | The renin-angiotensin-aldosterone system in adolescent offspring born prematurely to mothers with preeclampsia. ( Brosnihan, KB; Chappell, MC; Diz, DI; Gwathmey, TM; Nixon, PA; O'Shea, TM; Russell, GB; Snively, BM; Washburn, LK, 2015) |
"Hyponatremia in the setting of preeclampsia is an indicator of severity, and requires the understanding of the etiologic mechanisms to initiate an appropriate treatment." | 1.40 | [Electrolyte disorders in preeclampsia. A case report]. ( Bodenmann Gobin, P; Ducry, J; Gobin, N; Portmann, L; Vial, Y; Vogt, B, 2014) |
"Preeclampsia is associated with urinary excretion of plasmin(ogen) and plasmin-dependent activation of ENaC by urine." | 1.38 | Urinary plasmin activates collecting duct ENaC current in preeclampsia. ( Bistrup, C; Buhl, KB; Frederiksen-Møller, B; Friis, UG; Gulaveerasingam, A; Jensen, BL; Jespersen, B; Ovesen, P; Svenningsen, P, 2012) |
"However, these values in preeclampsia are decreased to nearly that of a nonpregnant subject, and vascular sensitivity to angiotensin II is increased." | 1.35 | The relationship between aldosterone to renin ratio and RI value of the uterine artery in the preeclamptic patient vs. normal pregnancy. ( Kim, EH; Kim, YH; Lim, JH; Park, YW, 2008) |
"Pregnant women with preeclampsia have increased serotonin levels, suggesting a possible role of this amine in abnormal pregnancy." | 1.34 | Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels. ( Aranda, E; Downey, P; Giacaman, A; Mezzano, D; Romero, W; Salas, SP; Vío, CP, 2007) |
"Aldosterone values were lower in PE from week 26 to 29 onwards and in FGR after week 34." | 1.33 | Time course of maternal plasma volume and hormonal changes in women with preeclampsia or fetal growth restriction. ( Gutiérrez, BL; Marshall, G; Rosso, P; Salas, SP, 2006) |
"In preeclamptic patients without intrauterine growth retardation (IUGR) the mean histological index H score was significantly higher, but significantly decreased in patients with preeclampsia complicated by IUGR in comparison with the control group." | 1.32 | Comparative analysis of the angiotensin-II receptor in placental vascular endothelial cells in preeclamptic and normotensive patients. ( Laskowska, K; Laskowska, M; Leszczyńska-Gorzelak, B; Oleszczuk, J; Szumiło, J; Vinson, GP, 2003) |
"Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified." | 1.31 | The renin-aldosterone system during normal and hypertensive pregnancy. ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001) |
"Pregnant patients with preeclampsia showed adaptation to the increase in systemic blood pressure, with significant modification of left ventricular structure and function related to the plasma levels of both atrial natriuretic peptide and brain natriuretic peptide." | 1.31 | Relationship of systemic hemodynamics, left ventricular structure and function, and plasma natriuretic peptide concentrations during pregnancy complicated by preeclampsia. ( Ambrosioni, E; Borghi, C; Boschi, S; Bovicelli, L; Cassani, A; Esposti, DD; Immordino, V, 2000) |
"Our studies revealed selective hypoaldosteronism with normal adrenoglucocorticoid functions." | 1.31 | Selective hypoaldosteronism due to combined defects of the conversion from inactive renin to active renin and the aldosterone biosynthesis from corticosterone. ( Akai, Y; Asano, Y; Kusano, E; Muto, S; Ono, S, 2001) |
"Primary aldosteronism rarely complicates pregnancy." | 1.31 | Diagnosis and management of primary aldosteronism in pregnancy: case report and review of the literature. ( Asano, K; Fujimori, K; Hashimoto, T; Okawa, T; Sato, A; Yanagida, K, 2002) |
"Animal models for preeclampsia are no alternative to clinical studies, but they are furthering our understanding of pathophysiology in many fields." | 1.30 | [Animal experiment models of hypertension in pregnancy--an alternative to clinical studies?]. ( Casper, F; Hropot, M; Leiser, R; Seufert, R, 1999) |
"We conclude that mild preeclampsia is associated with elevated plasma norepinephrine levels, lower systemic daytime production of prostacyclin, and blunting of the normal diurnal variation for a number of indices including plasma levels of BNP, ANP, norepinephrine, and aldosterone, and urinary prostacyclin metabolites." | 1.30 | Blood pressure and vasoactive hormones in mild preeclampsia and normal pregnancy. ( Frampton, CM; Kaaja, RJ; Moore, MP; Nicholls, MG; Yandle, TG; Ylikorkala, O, 1999) |
"Preeclampsia is accompanied by amplification of the sodium retention that is a feature of normal pregnancy." | 1.29 | 11 beta-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy. ( Brown, MA; Edwards, CR; Honour, JW; Walker, BR; Whitworth, JA; Williamson, PM, 1995) |
"The aldosterone levels were significantly greater in umbilical veins and artery than in maternal peripheral veins." | 1.28 | [Dopaminergic control of aldosterone and prolactin secretion during normal pregnancy and toxemia of pregnancy]. ( Niibe, T, 1989) |
"Furthermore, in preeclampsia, a particularly low ratio seemed to be typical of the patients who showed poorer placental flows and fetal outcomes." | 1.28 | Ratio between aldosterone and atrial natriuretic peptide in pregnancy. ( Canavese, C; Fianchino, O; Gagliardi, L; Gurioli, L; Mattone, GC; Porcu, M; Stratta, P; Todros, T; Vercellone, A, 1989) |
"A definite diagnosis of primary aldosteronism cannot be made during toxemia of pregnancy, and it is necessary to do serial determinations of plasma renin activity and plasma aldosterone concentration after delivery to confirm the diagnosis." | 1.27 | Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism. ( Akahoshi, M; Aoi, W; Doi, Y; Hashiba, K; Kuramochi, M; Shimizu, A; Suzuki, S; Utsunomiya, T, 1983) |
"In cases of severe preeclampsia, levels of atrial natriuretic peptide were significantly higher than in the other subjects, but aldosterone levels decreased to nearly those seen in the nonpregnant subjects." | 1.27 | Circadian rhythm of plasma atrial natriuretic peptide, aldosterone, and blood pressure during the third trimester in normal and preeclamptic pregnancies. ( Miyamoto, S; Nakano, H; Shimokawa, H; Sumioki, H; Touno, A, 1988) |
"Experimental toxemia of pregnancy was induced in 8 pregnant monkeys (Macacamulatta) by reducing the abdomiinal aorta to one-third of its original diameter during the last month of gestation." | 1.26 | Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone. ( Abitbol, MM; Driscoll, SG; Gallo, GR; Ober, MB; Pirani, CL, 1977) |
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group." | 1.26 | Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1982) |
"2) PRA and PA in toxemia of pregnancy were obviously lower in comparison with normal pregnancy in the corresponding period." | 1.26 | [Renin and aldosterone during pregnancy (author's transl)]. ( Mochizuki, M; Motoyama, S; Tojo, S, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 90 (58.06) | 18.7374 |
1990's | 17 (10.97) | 18.2507 |
2000's | 16 (10.32) | 29.6817 |
2010's | 24 (15.48) | 24.3611 |
2020's | 8 (5.16) | 2.80 |
Authors | Studies |
---|---|
Kametas, NA | 1 |
Nzelu, D | 1 |
Nicolaides, KH | 1 |
Menkhorst, E | 1 |
Zhou, W | 1 |
Santos, L | 1 |
Zhang, JG | 1 |
St-Pierre, Y | 1 |
Young, MJ | 1 |
Dimitriadis, E | 1 |
Biwer, LA | 1 |
Lu, Q | 1 |
Ibarrola, J | 1 |
Stepanian, A | 1 |
Man, JJ | 1 |
Carvajal, BV | 1 |
Camarda, ND | 1 |
Zsengeller, Z | 1 |
Skurnik, G | 1 |
Seely, EW | 1 |
Karumanchi, SA | 3 |
Jaffe, IZ | 1 |
Zitouni, H | 2 |
Chayeb, V | 1 |
Ben Ali Gannoun, M | 1 |
Raguema, N | 2 |
Bendhaher, S | 1 |
Zouari, I | 2 |
Ben Abdennebi, H | 1 |
Guibourdenche, J | 2 |
Mahjoub, T | 2 |
Gaddour, K | 1 |
Almawi, WY | 2 |
Alexander, BT | 1 |
South, AM | 1 |
August, P | 2 |
Bertagnolli, M | 1 |
Ferranti, EP | 1 |
Grobe, JL | 1 |
Jones, EJ | 1 |
Loria, AS | 1 |
Safdar, B | 1 |
Sequeira-Lopez, MLS | 1 |
Shoemaker, R | 1 |
Poglitsch, M | 1 |
Huang, H | 2 |
Vignes, K | 1 |
Srinivasan, A | 1 |
Cockerham, C | 1 |
Schadler, A | 1 |
Bauer, JA | 1 |
O'Brien, JM | 1 |
Meyer, LS | 1 |
Gong, S | 1 |
Reincke, M | 1 |
Williams, TA | 1 |
Nielsen, MR | 1 |
Frederiksen-Møller, B | 3 |
Zachar, R | 1 |
Jørgensen, JS | 3 |
Hansen, MR | 3 |
Ydegaard, R | 1 |
Svenningsen, P | 2 |
Buhl, K | 1 |
Jensen, BL | 5 |
Lei, J | 1 |
Zhang, S | 2 |
Wang, P | 1 |
Liao, Y | 1 |
Bian, J | 1 |
Yin, X | 1 |
Wu, Y | 2 |
Bai, L | 1 |
Wang, F | 1 |
Yang, X | 1 |
Liu, H | 2 |
Gannoun, MBA | 1 |
Hebert-Stutter, M | 1 |
Maleh, W | 1 |
Faleh, R | 1 |
Letaifa, DB | 1 |
Fournier, T | 1 |
Birukov, A | 1 |
Andersen, LB | 2 |
Herse, F | 1 |
Rakova, N | 1 |
Kitlen, G | 1 |
Kyhl, HB | 1 |
Golic, M | 1 |
Haase, N | 1 |
Kräker, K | 1 |
Müller, DN | 1 |
Andersen, MS | 1 |
Dechend, R | 1 |
Guo, M | 1 |
Zhou, C | 1 |
Xu, G | 1 |
Tang, L | 1 |
Ruan, Y | 1 |
Yu, Y | 1 |
Lin, X | 1 |
Wu, D | 1 |
Chen, H | 1 |
Yu, P | 1 |
Jin, L | 1 |
Wang, Y | 1 |
Ullah, K | 1 |
Rahman, TU | 1 |
Liu, X | 1 |
Sheng, J | 1 |
Chan, HC | 1 |
Gennari-Moser, C | 2 |
Khankin, EV | 2 |
Escher, G | 4 |
Burkhard, F | 2 |
Frey, BM | 2 |
Frey, FJ | 3 |
Mohaupt, MG | 4 |
Delles, C | 1 |
Freel, EM | 1 |
Radkov, OV | 1 |
Kalinkin, MN | 1 |
Zavarin, VV | 1 |
Verdonk, K | 2 |
Visser, W | 2 |
van den Meiracker, AH | 2 |
Danser, AH | 2 |
Bodenmann Gobin, P | 1 |
Gobin, N | 1 |
Ducry, J | 1 |
Portmann, L | 1 |
Vial, Y | 1 |
Vogt, B | 1 |
Washburn, LK | 1 |
Brosnihan, KB | 1 |
Chappell, MC | 1 |
Diz, DI | 1 |
Gwathmey, TM | 1 |
Nixon, PA | 1 |
Russell, GB | 1 |
Snively, BM | 1 |
O'Shea, TM | 1 |
Yang, J | 2 |
Li, L | 1 |
Shang, JY | 1 |
Cai, L | 1 |
Song, L | 1 |
Zhang, SL | 1 |
Li, H | 2 |
Li, X | 1 |
Lau, WB | 1 |
Ma, XL | 1 |
Liu, HR | 1 |
Armanini, D | 3 |
Sabbadin, C | 1 |
Donà, G | 1 |
Andrisani, A | 1 |
Ambrosini, G | 1 |
Bordin, L | 1 |
Krigslund, O | 1 |
Vogel, LK | 1 |
Umazume, T | 1 |
Morikawa, M | 1 |
Yamada, T | 1 |
Minakami, H | 1 |
Nielsen, LH | 1 |
Ovesen, P | 2 |
Brantlov, S | 1 |
Jespersen, B | 2 |
Bie, P | 1 |
Scaife, PJ | 1 |
Del Mónaco, SM | 1 |
Marino, G | 1 |
Assef, Y | 1 |
Kotsias, BA | 2 |
Cristiano, M | 1 |
Causevic, M | 1 |
Baumann, M | 1 |
Surbek, D | 1 |
Lindheimer, MD | 7 |
Todkar, A | 1 |
Di Chiara, M | 1 |
Loffing-Cueni, D | 1 |
Bettoni, C | 1 |
Mohaupt, M | 2 |
Loffing, J | 1 |
Wagner, CA | 1 |
Buhl, KB | 1 |
Friis, UG | 1 |
Gulaveerasingam, A | 1 |
Bistrup, C | 1 |
Marino, GI | 1 |
Rossitto, G | 1 |
Regolisti, G | 1 |
Rossi, E | 1 |
Negro, A | 1 |
Nicoli, D | 1 |
Casali, B | 1 |
Toniato, A | 1 |
Caroccia, B | 1 |
Seccia, TM | 1 |
Walther, T | 1 |
Rossi, GP | 1 |
Siddiqui, AH | 1 |
Irani, RA | 1 |
Zhang, W | 1 |
Wang, W | 2 |
Blackwell, SC | 1 |
Kellems, RE | 1 |
Xia, Y | 1 |
Shang, J | 1 |
Laskowska, M | 2 |
Vinson, GP | 1 |
Szumiło, J | 1 |
Laskowska, K | 2 |
Leszczyńska-Gorzelak, B | 2 |
Oleszczuk, J | 2 |
KOCZOREK, KR | 1 |
WOLFF, HP | 1 |
BEER, ML | 1 |
SCHUURMANS, R | 1 |
BUCKINGHAM, JC | 1 |
BARNES, AC | 2 |
KUMAR, D | 2 |
FELTHAM, LA | 1 |
GORNALL, AG | 1 |
de BRUINE, T | 1 |
STARK, G | 4 |
SKALICKY, J | 1 |
THOMAS, JP | 1 |
FLYNN, TG | 1 |
FERREIRA, AC | 1 |
LOUROS, NC | 1 |
MIRAS, K | 1 |
FRANGIADAKIS, L | 1 |
RAVENNI, G | 1 |
RUBEGNI, M | 1 |
BOCCI, F | 1 |
RICHTER, RH | 1 |
ARNOLD, M | 1 |
Calò, LA | 1 |
Salas, SP | 2 |
Marshall, G | 1 |
Gutiérrez, BL | 1 |
Rosso, P | 1 |
Giacaman, A | 1 |
Romero, W | 1 |
Downey, P | 1 |
Aranda, E | 1 |
Mezzano, D | 1 |
Vío, CP | 1 |
Kim, EH | 1 |
Lim, JH | 1 |
Kim, YH | 1 |
Park, YW | 1 |
Kokot, F | 3 |
Ulman, J | 2 |
Cekański, A | 3 |
Pedersen, EB | 5 |
Christensen, NJ | 3 |
Christensen, P | 3 |
Johannesen, P | 5 |
Kornerup, HJ | 4 |
Kristensen, S | 3 |
Lauritsen, JG | 3 |
Leyssac, PP | 3 |
Rasmussen, AB | 5 |
Wohlert, M | 3 |
Shimizu, A | 1 |
Aoi, W | 1 |
Akahoshi, M | 1 |
Utsunomiya, T | 1 |
Doi, Y | 1 |
Suzuki, S | 1 |
Kuramochi, M | 1 |
Hashiba, K | 1 |
Barron, WM | 1 |
Aalkjaer, C | 1 |
Danielsen, H | 2 |
Mulvany, M | 1 |
Enhorning, G | 1 |
Fisher, KA | 1 |
Katz, AI | 4 |
Motoyama, S | 1 |
Mochizuki, M | 1 |
Tojo, S | 1 |
Saruta, T | 2 |
Nakamura, R | 3 |
Nagahama, S | 1 |
Suzuki, H | 1 |
Kondo, K | 2 |
Poreba, R | 1 |
Ayuk Mbu, J | 1 |
Mühlbach, F | 2 |
Bellée, H | 2 |
Hubl, W | 2 |
Büchner, M | 2 |
Den, K | 1 |
Tomita, M | 1 |
Miyake, Y | 1 |
Yamaguchi, N | 1 |
Fukasawa, M | 1 |
Teramoto, K | 1 |
Takagi, S | 2 |
Walker, BR | 1 |
Williamson, PM | 1 |
Brown, MA | 3 |
Honour, JW | 1 |
Edwards, CR | 1 |
Whitworth, JA | 3 |
Thou, ST | 1 |
Dai, LT | 1 |
Reiter, L | 1 |
Rodger, A | 1 |
Tsai, YL | 1 |
Wu, SJ | 1 |
Chen, YM | 1 |
Hsieh, BS | 1 |
Stratta, P | 2 |
Canavese, C | 2 |
Piccoli, G | 1 |
Todros, T | 2 |
Benedetto, C | 1 |
Bussen, SS | 1 |
Sütterlin, MW | 1 |
Steck, T | 1 |
Kaaja, RJ | 1 |
Moore, MP | 1 |
Yandle, TG | 1 |
Ylikorkala, O | 1 |
Frampton, CM | 1 |
Nicholls, MG | 1 |
Hennessy, A | 1 |
Gillin, AG | 1 |
Duggin, GG | 1 |
Horvath, JS | 1 |
Tiller, DJ | 1 |
Seufert, R | 2 |
Hropot, M | 1 |
Casper, F | 2 |
Leiser, R | 1 |
Pollow, K | 1 |
Schäfer, W | 1 |
Zahradnik, HP | 1 |
Hassan, E | 1 |
Creatsas, G | 2 |
Mastorakos, G | 2 |
Michalas, S | 2 |
Borghi, C | 1 |
Esposti, DD | 1 |
Immordino, V | 1 |
Cassani, A | 1 |
Boschi, S | 1 |
Bovicelli, L | 1 |
Ambrosioni, E | 1 |
Elsheikh, A | 1 |
Milingos, S | 1 |
Loutradis, D | 1 |
Muto, S | 1 |
Akai, Y | 1 |
Ono, S | 1 |
Kusano, E | 1 |
Asano, Y | 1 |
Long, W | 1 |
Li, G | 1 |
Yang, H | 1 |
Okawa, T | 1 |
Asano, K | 1 |
Hashimoto, T | 1 |
Fujimori, K | 1 |
Yanagida, K | 1 |
Sato, A | 1 |
Takeda, Y | 1 |
Yoneda, T | 1 |
Demura, M | 1 |
Furukawa, K | 1 |
Usukura, M | 1 |
Mabuchi, H | 1 |
Nolten, WE | 1 |
Oparil, S | 1 |
Ehrlich, EN | 2 |
Shekhtman, MM | 2 |
Ober, WB | 1 |
Lindberg, BS | 1 |
Hayashi, M | 1 |
Saito, I | 1 |
Kato, E | 1 |
Sann, L | 1 |
Coiffet, J | 1 |
Bethenod, M | 1 |
Abitbol, MM | 1 |
Ober, MB | 1 |
Gallo, GR | 1 |
Driscoll, SG | 1 |
Pirani, CL | 1 |
Dörner, G | 1 |
Brod, J | 2 |
Annat, G | 1 |
Raudrant, D | 1 |
Chappe, J | 1 |
Vincent, M | 1 |
Thoulon, J | 1 |
Dumont, M | 1 |
Sassard, J | 1 |
Tochigi, T | 1 |
Yoshida, T | 1 |
Makino, T | 1 |
Kanbegawa, A | 1 |
Kyank, H | 1 |
Neumayer, E | 1 |
During, R | 1 |
Weinberger, MH | 1 |
Kramer, NJ | 1 |
Petersen, LP | 1 |
Cleary, RE | 1 |
Young, PC | 1 |
Egorova, IA | 1 |
Vinogradova, LA | 1 |
Baehler, RW | 1 |
Copeland, WE | 1 |
Stein, JH | 1 |
Ferris, TF | 1 |
Riemer, WD | 1 |
Prott, V | 1 |
Zennaro, CM | 1 |
Martella, L | 1 |
Scali, M | 1 |
Pratesi, C | 1 |
Grella, PV | 1 |
Mantero, F | 1 |
Vokaer, A | 1 |
Clark, BA | 1 |
Halvorson, L | 1 |
Sachs, B | 1 |
Epstein, FH | 1 |
de Jong, CL | 1 |
Dekker, GA | 1 |
Sibai, BM | 1 |
Mikkelsen, AL | 1 |
Schütten, G | 1 |
Asping, U | 1 |
Schütten, HJ | 1 |
Gurioli, L | 1 |
Porcu, M | 1 |
Mattone, GC | 1 |
Fianchino, O | 1 |
Gagliardi, L | 1 |
Vercellone, A | 1 |
Ferrazzani, S | 1 |
Leardi, P | 1 |
Magnotti, DL | 1 |
De Carolis, S | 1 |
Moneta, E | 1 |
Porcelli, G | 1 |
Volpe, AR | 1 |
Menini, E | 1 |
Liberale, I | 1 |
Niibe, T | 1 |
Gregoire, I | 1 |
Roth, D | 1 |
Siegenthaler, G | 1 |
Fievet, P | 1 |
el Esper, N | 1 |
Favre, H | 1 |
Fournier, A | 1 |
Stevens, KJ | 1 |
Paintin, DB | 1 |
Few, JD | 1 |
Miyamoto, S | 1 |
Shimokawa, H | 1 |
Sumioki, H | 1 |
Touno, A | 1 |
Nakano, H | 1 |
D'Anna, R | 1 |
Sciarrone, A | 1 |
Mantov, S | 1 |
Lin'ova, V | 1 |
Maleeva, A | 1 |
Kozhukharova, M | 1 |
Mirkov, K | 1 |
Oian, P | 1 |
Kjeldsen, SE | 1 |
Eide, I | 1 |
Norman, N | 1 |
Montoneri, C | 1 |
Lo Presti, L | 1 |
Giardinella, S | 1 |
Garofalo, A | 1 |
Panella, M | 1 |
Del Greco, F | 1 |
Krumlovsky, FA | 1 |
Hartog, M | 1 |
Gross, F | 2 |
Vedra, B | 2 |
Tanaka, T | 1 |
Kobayashi, H | 1 |
Honda, H | 1 |
Fukuda, T | 1 |
Miyama, S | 1 |
Sims, EA | 2 |
Laragh, JH | 1 |
Robertson, JI | 1 |
Weir, RJ | 1 |
Düsterdieck, GO | 1 |
Fraser, R | 1 |
Tree, M | 1 |
Mukherjee, K | 1 |
Swyer, GI | 1 |
Atkinson, SM | 1 |
Speroff, L | 1 |
Ménard, J | 1 |
Corvol, P | 1 |
London, H | 1 |
Tcherdakoff, P | 1 |
Chesley, LC | 1 |
Vick, H | 1 |
Gray, MJ | 2 |
Friedberg, CK | 1 |
Yoshida, H | 1 |
Mizukoshi, H | 1 |
Araki, Y | 1 |
Salvadori, B | 1 |
Speranskaia, NV | 1 |
Iureva, ZL | 1 |
Baksheev, NS | 1 |
Kavunets, GP | 2 |
Horská, S | 1 |
Lloyd, IJ | 1 |
Burstyn, PG | 1 |
Horrobin, DF | 1 |
Kahuho, SK | 1 |
Mulimba, O | 1 |
Webala, GS | 1 |
Ivanova, AS | 1 |
Watanabe, M | 1 |
Meeker, CI | 1 |
Solomon, S | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Increased Activity of the Epithelial Sodium Channel (ENaC) in Diabetic Nephropathy[NCT01918488] | 80 participants (Anticipated) | Interventional | 2013-10-31 | Enrolling by invitation | |||
Prospective Cohort Evaluation of Cardiac Function With Echocardiography and Serum B-type Natriuretic Peptide (BNP) in Obstetrical Patients With and Without a History of Cardiac Disease[NCT00759733] | 0 participants (Actual) | Observational | 2008-07-31 | Withdrawn (stopped due to No participants enrolled) | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
31 reviews available for aldosterone and Edema-Proteinuria-Hypertension Gestosis
Article | Year |
---|---|
Chronic hypertension and superimposed preeclampsia: screening and diagnosis.
Topics: Aldosterone; Angiogenic Proteins; Biomarkers; Chronic Disease; Cytokines; Female; Humans; Hypertensi | 2022 |
Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American
Topics: Aldosterone; American Heart Association; Cardiovascular Diseases; Female; Humans; Hypertension; Moth | 2023 |
Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II Type 1 Receptor Blocke | 2020 |
The renin-angiotensin-aldosterone system in pre-eclampsia: the delicate balance between good and bad.
Topics: Aldosterone; Animals; Female; Humans; Pre-Eclampsia; Pregnancy; Receptor, Angiotensin, Type 1; Renin | 2014 |
Salt, aldosterone and extrarenal Na
Topics: Aldosterone; Animals; Blood Pressure; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Sodium | 2017 |
Aldosterone, maternal volume status and healthy pregnancies: a cycle of differing views.
Topics: Aldosterone; Blood Volume; Female; Humans; Models, Biological; Pre-Eclampsia; Pregnancy; Renin-Angio | 2009 |
The role of the renin-angiotensin-aldosterone system in preeclampsia: genetic polymorphisms and microRNA.
Topics: Aldosterone; Angiotensinogen; Female; Gene Expression Regulation; Humans; MicroRNAs; Mutation; Pepti | 2013 |
Role of aldosterone availability in preeclampsia.
Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Humans; Models, Biological; Pre-Eclam | 2007 |
Renal sodium and water handling in pregnancy.
Topics: Aldosterone; Body Weight; Desoxycorticosterone; Diuretics; Female; Glomerular Filtration Rate; Homeo | 1984 |
Hypertension in pregnancy.
Topics: Aldosterone; Angiotensins; Female; Humans; Hypertension; Kidney; Pre-Eclampsia; Pregnancy; Pregnancy | 1980 |
Clinical implications of the ovarian/endometrial renin-angiotensin-aldosterone system.
Topics: Aldosterone; Animals; Endometrium; Female; Humans; Hypertension; Male; Menstrual Cycle; Ovary; Pre-E | 2000 |
Sodium and mineralocorticoids in normal and abnormal pregnancy.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Animals; Blood Volume; Body Weight; Circadian Rhyth | 1977 |
[Pathogenesis of edema in pregnant women].
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Volume; Edema; Extracellular Space; Female; Glomerul | 1978 |
Experimental toxemia of pregnancy: review and speculation.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Dogs; Endocrine Glands; Female; Humans | 1977 |
Salt, diuretics and pregnancy.
Topics: Aldosterone; Angiotensin II; Animals; Benzothiadiazines; Diuretics; Female; Glomerular Filtration Ra | 1979 |
The renin-angiotensin-aldosterone system in preeclampsia. A review.
Topics: Aldosterone; Angiotensin II; Biochemical Phenomena; Biochemistry; Female; Hemodynamics; Humans; Kall | 1991 |
[Vasoactive substances in normal pregnancy and in pregnancy complicated by gestosis].
Topics: Aldosterone; Female; Humans; Hypertension; Kallikreins; Pre-Eclampsia; Pregnancy; Pregnancy Complica | 1988 |
The renal pressor system in human pregnancy.
Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Ju | 1972 |
Human chorionic somatomammotrophin and its clinical significance.
Topics: Abortion, Threatened; Aldosterone; Animals; Carbohydrate Metabolism; Choriocarcinoma; Diabetes Melli | 1972 |
[The renin-angiotensin-aldosterone system in late gestosis].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Pre-Eclampsia; | 1968 |
[Experimental bases of the pathophysiology of the renin-angiotensin system].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hyperaldosteronism; Hypertensi | 1968 |
[Renovascular hypertension in pregnancy].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Chronic Disease; Female; Humans; Hypertension, Renal; K | 1969 |
Pre-eclampsia and related complications of pregnancy.
Topics: Adult; Aldosterone; Angiotensin II; Blood Coagulation Disorders; Catecholamines; Diagnosis, Differen | 1970 |
Renin, angiotensin and aldosterone in human pregnancy and the menstrual cycle.
Topics: Adult; Aldosterone; Amniotic Fluid; Angiotensin II; Endopeptidases; Estrogens; Extraembryonic Membra | 1971 |
Salt, water, and rest as a preventative for toxemia of pregnancy. A commentary and review.
Topics: Aldosterone; Angiotensin II; Blood Volume; Body Weight; Diabetes Insipidus; Diuresis; Diuretics; Ede | 1972 |
Renin, angiotensin, and aldosterone.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Endopeptidases; Female; Glomer | 1974 |
Sodium metabolism, aldosterone and the hypertensive disorders of pregnancy.
Topics: Aldosterone; Diuretics; Estrogens; Female; Humans; Hypertension; Posture; Pre-Eclampsia; Pregnancy; | 1972 |
Sodium and diuretics in pregnancy.
Topics: Aldosterone; Animals; Body Water; Body Weight; Diuretics; Edema; Female; Homeostasis; Humans; Kidney | 1973 |
Use and abuse of thiazides in pregnancy.
Topics: Aldosterone; Diabetes Mellitus; Diuretics; Edema; Female; Hematologic Diseases; Humans; Hypokalemia; | 1968 |
Edema and pulmonary edema: pathologic physiology and differential diagnosis.
Topics: Adrenal Glands; Aldosterone; Diagnosis, Differential; Edema; Extracellular Space; Female; Heart Dise | 1971 |
[The third factor].
Topics: Aldosterone; Animals; Biological Assay; Dogs; Extracorporeal Circulation; Female; Glomerular Filtrat | 1971 |
3 trials available for aldosterone and Edema-Proteinuria-Hypertension Gestosis
Article | Year |
---|---|
Changes in the renin-angiotensin-aldosterone system in response to dietary salt intake in normal and hypertensive pregnancy. A randomized trial.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure Determination; Creatinine; Diet, Sodium-Restricte | 2016 |
Prostaglandins, renin, aldosterone, and catecholamines in preeclampsia.
Topics: Aldosterone; Blood Pressure; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Norepinephrine; P | 1983 |
Stimulation of aldosterone by ACTH in normal and hypertensive pregnancy.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Pre-E | 1995 |
121 other studies available for aldosterone and Edema-Proteinuria-Hypertension Gestosis
Article | Year |
---|---|
Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia.
Topics: Aldosterone; Angiotensins; Animals; Female; Galectins; Humans; Hypertension; Mice; NADP; NADPH Oxida | 2022 |
Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia.
Topics: Aldosterone; Animals; Female; Humans; Hypertension; Mice; Muscle, Smooth; Pre-Eclampsia; Pregnancy; | 2023 |
Preeclampsia is associated with reduced renin, aldosterone, and PlGF levels, and increased sFlt-1/PlGF ratio, and specific angiotensin-converting enzyme Ins-Del gene variants.
Topics: Aldosterone; Angiotensins; Biomarkers; Birth Weight; Female; Humans; Placenta Growth Factor; Pre-Ecl | 2023 |
Activation of the Renin-Angiotensin-Aldosterone System Is Attenuated in Hypertensive Compared with Normotensive Pregnancy.
Topics: Aldosterone; Angiotensin II; Chromatography, Liquid; Female; Humans; Hypertension, Pregnancy-Induced | 2023 |
Urine exosomes from healthy and hypertensive pregnancies display elevated level of α-subunit and cleaved α- and γ-subunits of the epithelial sodium channel-ENaC.
Topics: Adult; Aldosterone; Epithelial Sodium Channels; Exosomes; Female; Fibrinolysin; Humans; Hypertension | 2017 |
Long-term presence of angiotensin II type 1 receptor autoantibody reduces aldosterone production by triggering Ca
Topics: Adrenal Cortex Neoplasms; Aldosterone; Autoantibodies; Autoantigens; Calcium; Calcium Channels; Calc | 2018 |
Impact of obesity on the association of active renin and plasma aldosterone concentrations, and aldosterone-to-renin ratio with preeclampsia.
Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Female; Humans; Obesity; Pre-Eclampsia; Pr | 2018 |
Aldosterone, Salt, and Potassium Intakes as Predictors of Pregnancy Outcome, Including Preeclampsia.
Topics: Adult; Aldosterone; Cohort Studies; Denmark; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inci | 2019 |
An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction.
Topics: Adult; Aldosterone; Alternative Splicing; Blood Pressure; DNA, Complementary; Endothelial Cells; Fem | 2020 |
Vascular endothelial growth factor-A and aldosterone: relevance to normal pregnancy and preeclampsia.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Cell Line; Cells, Cultured; Cytochrome P-450 C | 2013 |
Aldosterone, vascular endothelial growth factor, and preeclampsia: a mystery solved?
Topics: Aldosterone; Animals; Female; Humans; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System; Vascular E | 2013 |
Genophenotypic analysis of angiotensinogen gene M235T polymorphism and preeclampsia.
Topics: Aldosterone; Alleles; Angiotensinogen; Blood Pressure; Female; Gene Frequency; Genotype; Humans; Phe | 2013 |
Are aldosterone levels inappropriately low in preeclampsia?
Topics: Aldosterone; Animals; Female; Humans; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System; Vascular E | 2013 |
Response to "Are aldosterone levels inappropriately low in preeclampsia"?
Topics: Aldosterone; Animals; Female; Humans; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System; Vascular E | 2013 |
[Electrolyte disorders in preeclampsia. A case report].
Topics: Adult; Aldosterone; Antihypertensive Agents; Capillary Leak Syndrome; Cesarean Section; Emergencies; | 2014 |
The renin-angiotensin-aldosterone system in adolescent offspring born prematurely to mothers with preeclampsia.
Topics: Adolescent; Aldosterone; Female; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Male; Mothe | 2015 |
Angiotensin II type 1 receptor autoantibody as a novel regulator of aldosterone independent of preeclampsia.
Topics: Adrenal Cortex; Adult; Aldosterone; Animals; Autoantibodies; Blood Pressure; Case-Control Studies; C | 2015 |
Maternal and Fetal Outcomes in Preeclampsia: Interrelations Between Insulin Resistance, Aldosterone, Metabolic Syndrome, and Polycystic Ovary Syndrome.
Topics: Aldosterone; Female; Humans; Hypertension; Insulin; Insulin Resistance; Metabolic Syndrome; Polycyst | 2015 |
Prostasin and matriptase (ST14) in placenta from preeclamptic and healthy pregnant women.
Topics: Adult; Aldosterone; Animals; Case-Control Studies; Cross-Sectional Studies; Epithelial Sodium Channe | 2016 |
Changes in echocardiography and blood variables during and after development of Ballantyne syndrome.
Topics: Adult; Aldosterone; Biomarkers; Echocardiography; Female; Fibrinolytic Agents; Furosemide; Heparin; | 2016 |
[Preeclampsia, cellular migration and ion channels].
Topics: Aldosterone; Cell Line; Cell Movement; Epithelial Sodium Channels; Female; Humans; Placenta; Pre-Ecl | 2008 |
High aldosterone-to-renin variants of CYP11B2 and pregnancy outcome.
Topics: Adult; Aldosterone; Base Sequence; Blood Pressure; Case-Control Studies; Cytochrome P-450 CYP11B2; D | 2009 |
Aldosterone deficiency adversely affects pregnancy outcome in mice.
Topics: Aldosterone; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Diet; Disease Models, Animal; Female | 2012 |
Urinary plasmin activates collecting duct ENaC current in preeclampsia.
Topics: Adult; Albuminuria; Aldosterone; Blotting, Western; Creatinine; Cross-Sectional Studies; Epithelial | 2012 |
Expression of the epithelial sodium channel sensitive to amiloride (ENaC) in normal and preeclamptic human placenta.
Topics: Aldosterone; Amiloride; Case-Control Studies; Epithelial Sodium Channel Blockers; Epithelial Sodium | 2013 |
Elevation of angiotensin-II type-1-receptor autoantibodies titer in primary aldosteronism as a result of aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Autoantibodies; Autoimmunity; Diagnosis | 2013 |
Angiotensin receptor agonistic autoantibody-mediated soluble fms-like tyrosine kinase-1 induction contributes to impaired adrenal vasculature and decreased aldosterone production in preeclampsia.
Topics: Adoptive Transfer; Adrenal Glands; Adult; Aldosterone; Animals; Autoantibodies; Disease Models, Anim | 2013 |
Comparative analysis of the angiotensin-II receptor in placental vascular endothelial cells in preeclamptic and normotensive patients.
Topics: Aldosterone; Angiotensin II; Apgar Score; Birth Weight; Blood Pressure; Endothelial Cells; Female; F | 2003 |
[Aldosterone excretion in pregnancy and in pregnancy toxicosis].
Topics: Aldosterone; Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy | 1957 |
[Aldosterone and pregnancy toxicoses].
Topics: Aldosterone; Female; Humans; Pre-Eclampsia; Pregnancy | 1957 |
Electrolyte balance studies with a new aldosterone antagonist in the toxemias of pregnancy.
Topics: Aldosterone; Antihypertensive Agents; Diuretics; Female; Hormone Antagonists; Humans; Mineralocortic | 1958 |
Aldosterone excretion and tissue electrolytes in normal pregnancy and pre-eclampsia.
Topics: Aldosterone; Eclampsia; Electrolytes; Female; Humans; Pre-Eclampsia; Pregnancy | 1959 |
Aldosterone in normal and abnormal pregnancy.
Topics: Aldosterone; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications | 1960 |
[Urinary aldosterone at the end of normal and pathological pregnancies].
Topics: Aldosterone; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy | 1961 |
[Our experiences with the aldosterone blocking agent, aldactone in obstetrics].
Topics: Aldosterone; Body Fluids; Diuretics; Female; Humans; Mineralocorticoid Receptor Antagonists; Obstetr | 1962 |
[ADRENAL CORTEX HORMONES IN SOME GESTOSES].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aldosterone; Blood Chemical Analysis; Blood Pressure Deter | 1963 |
ADRENAL FUNCTION IN NORMAL PREGNANCY AND TOXAEMIA.
Topics: Aldosterone; Bacterial Infections; Calcium Isotopes; Female; Humans; Pituitary-Adrenal Function Test | 1964 |
[ALDOSTERONE IN PREGNANCY].
Topics: Aldosterone; Body Fluids; Female; Humans; Metabolism; Pre-Eclampsia; Pregnancy; Sodium; Sodium, Diet | 1964 |
[Aldosterone- and pregnanediol excretion in the urine in normal pregnancy and in pregnancy toxemias (preliminary report)].
Topics: Aldosterone; Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnanedi | 1960 |
[Aldosterone during normal and pathological pregnancy].
Topics: Aldosterone; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy | 1959 |
[Observations on the effect of the aldosterone antagonist spironolactone (aldactone) in normal and toxemic pregnancy (preliminary report)].
Topics: Aldosterone; Antihypertensive Agents; Diuretics; Female; Hormone Antagonists; Humans; Mineralocortic | 1961 |
Aldosterone, inflammation, and preeclampsia.
Topics: Aldosterone; Female; Humans; Inflammation; Pre-Eclampsia; Pregnancy | 2005 |
Evaluation of the renin-angiotensin-aldosterone system in pregnancy complicated by preeclampsia with and without intrauterine growth retardation.
Topics: Aldosterone; Angiotensin II; Birth Weight; Female; Fetal Growth Retardation; Humans; Infant, Newborn | 2004 |
Time course of maternal plasma volume and hormonal changes in women with preeclampsia or fetal growth restriction.
Topics: Adult; Aldosterone; Case-Control Studies; Estradiol; Female; Fetal Growth Retardation; Hormones; Hum | 2006 |
Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels.
Topics: 5-Hydroxytryptophan; Aldosterone; Animals; Blood Pressure; Creatinine; Disease Models, Animal; Femal | 2007 |
The relationship between aldosterone to renin ratio and RI value of the uterine artery in the preeclamptic patient vs. normal pregnancy.
Topics: Adult; Aldosterone; Arteries; Case-Control Studies; Female; Gestational Age; Health; Humans; Pre-Ecl | 2008 |
[On aldosterone and electrolyte metabolism in pregnancy].
Topics: Adult; Aldosterone; Eclampsia; Female; Humans; Injections, Intravenous; Potassium; Pre-Eclampsia; Pr | 1966 |
Influence of head-out water immersion on plasma renin activity, aldosterone, vasopressin and blood pressure in late pregnancy toxaemia.
Topics: Adult; Aldosterone; Arginine Vasopressin; Blood Pressure; Female; Humans; Immersion; Osmolar Concent | 1983 |
Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Aortic Dissection; Aortic Rupture; Female; Hu | 1983 |
Renin, angiotensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancy.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female; Humans | 1984 |
Pre-eclampsia: a hypothesis for its pathogenesis.
Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Posture; Pre-Eclampsia; Pregn | 1984 |
The renin-aldosterone system in pre-eclampsia, essential and transient hypertension during pregnancy, and normotensive pregnant and non-pregnant control subjects.
Topics: Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Potassium; Pre-Eclampsia; Pre | 1982 |
Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy.
Topics: Aldosterone; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pre | 1982 |
[Renin and aldosterone during pregnancy (author's transl)].
Topics: Adult; Aldosterone; Birth Weight; Female; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnan | 1980 |
Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contrac | 1981 |
[Renin activity and plasma aldosterone levels in ulnar and uterine veins and in cord blood in normal pregnancy and pregnancy toxemias].
Topics: Aldosterone; Female; Fetal Blood; Forearm; Humans; Pre-Eclampsia; Pregnancy; Renin; Uterus; Veins | 1981 |
[Plasma aldosterone in pregnancy, during labor and in the newborn infant].
Topics: Aldosterone; Cesarean Section; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; Mater | 1982 |
Studies of maternal and fetal 11-deoxycorticosterone, corticosterone,18-hydroxycorticosterone and aldosterone in normal and toxemic pregnancy.
Topics: 18-Hydroxycorticosterone; Aldosterone; Animals; Corticosterone; Desoxycorticosterone; Female; Fetal | 1980 |
11 beta-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Blood Pressure; Female; Humans; Hydrocort | 1995 |
[Relation between somatostatin, atrial natriuretic peptide, beta-endorphin, aldosterone and pregnancy induced hypertension].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; beta-Endorphin; Biomarkers; Female; Fetal Blood; Huma | 1993 |
Impaired renin stimulation in pre-eclampsia.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Female; Furosemide; Hematocrit; Humans; Pre-Eclampsia; Pr | 1994 |
Changes in renin activity, aldosterone level and electrolytes in pregnancy-induced hypertension.
Topics: Adult; Aldosterone; Electrolytes; Female; Humans; Pre-Eclampsia; Pregnancy; Prospective Studies; Ren | 1993 |
Early prediction of pre-eclampsia by measurement of kallikrein and creatinine on a random urine sample.
Topics: Aldosterone; Atrial Natriuretic Factor; Creatinine; Female; Humans; Kallikreins; Pre-Eclampsia; Pred | 1997 |
Plasma renin activity and aldosterone serum concentration are decreased in severe preeclampsia but not in the HELLP-syndrome.
Topics: Adult; Aldosterone; Estradiol; Estriol; Female; HELLP Syndrome; Humans; Infant, Newborn; Pre-Eclamps | 1998 |
Blood pressure and vasoactive hormones in mild preeclampsia and normal pregnancy.
Topics: Adult; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Chromatography, High Pressure L | 1999 |
Low-dose nitro-L-arginine administration in baboon (Papio hamadryas) pregnancy.
Topics: Aldosterone; Animals; Body Weight; Endothelins; Enzyme Inhibitors; Female; Hemodynamics; Male; Nitri | 1999 |
[Animal experiment models of hypertension in pregnancy--an alternative to clinical studies?].
Topics: Aldosterone; Animals; Disease Models, Animal; Female; Hematocrit; Humans; Hypertension; Infant, Newb | 1999 |
[Epidemiology, risk factors and predictors of pre-eclampsia].
Topics: Adult; Aldosterone; Cross-Sectional Studies; Dinoprostone; Female; Humans; Incidence; Infant, Newbor | 1999 |
Relationship of systemic hemodynamics, left ventricular structure and function, and plasma natriuretic peptide concentrations during pregnancy complicated by preeclampsia.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Echocardiography; Female; Gestational | 2000 |
The renin-aldosterone system during normal and hypertensive pregnancy.
Topics: Adult; Aldosterone; Birth Weight; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy | 2001 |
Selective hypoaldosteronism due to combined defects of the conversion from inactive renin to active renin and the aldosterone biosynthesis from corticosterone.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Fem | 2001 |
Primary aldosteronism in pregnancy: review of cases.
Topics: Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Pre-Eclampsia; Preg | 1999 |
Diagnosis and management of primary aldosteronism in pregnancy: case report and review of the literature.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Cesarean Section; Female; Human | 2002 |
19-Noraldosterone in pregnancy-induced hypertension.
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Mineralocorticoids; Pre-Eclampsia; Pregnancy; Recept | 2002 |
Active and inactive renin in pregnancy and in women on estrogen-containing oral contraceptives.
Topics: Adult; Aldosterone; Angiotensinogen; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Estradio | 1979 |
[Neonatal hyponatremia from maternal origin. Three cases (author's transl)].
Topics: Adult; Aldosterone; Female; Hemodilution; Humans; Hyponatremia; Infant, Newborn; Infant, Newborn, Di | 1979 |
Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone.
Topics: Aldosterone; Animals; Aorta; Constriction; Disease Models, Animal; Female; Haplorhini; Hypertension; | 1977 |
Study of plasma aldosterone in normal pregnancy, in pre-eclamptic women and in cord plasma of newborns.
Topics: Aldosterone; Female; Fetal Blood; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy Trime | 1979 |
[A nephrologist's thoughts on pregnancy toxemia].
Topics: Aldosterone; Angiotensins; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Hy | 1979 |
Maternal and fetal plasma renin and dopamine-beta-hydroxylase activities in toxemic pregnancy.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Dopamine beta-Hydroxylase; Estradiol; Female; Fe | 1978 |
[Radioimmunoassay of plasma aldosterone and its clinical application].
Topics: Adult; Aldosterone; Female; Humans; Male; Pre-Eclampsia; Pregnancy; Radioimmunoassay | 1976 |
[A critical review of hypothetical causes of EPH-gestosis].
Topics: Aldosterone; Angiotensin II; Animals; Biogenic Amines; Blood Volume; Body Fluids; Edema; Female; Fib | 1976 |
Sequential changes in the renin--angiotensin--aldosterone systems and plasma progesterone concentration in normal and abnormal human pregnancy.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy | 1976 |
[Renin-angiotensin-aldosterone system in physiological pregnancy and pregnancy complications].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy | 1975 |
Plasma renin and aldosterone in an abdominal pregnancy with toxemia.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Ischemia; Placenta; Pre-Eclampsia; Pregnancy; Preg | 1975 |
[Behavior of blood pressure during oral hormonal anticonception].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Contraceptives | 1975 |
Mineralocorticoid effector mechanism in preeclampsia.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Leukocytes, Mononuclear; Mineralocorticoids; Pre | 1992 |
[Biological prediction of pre-eclampsia: the vasoactive substances].
Topics: Aldosterone; Atrial Natriuretic Factor; Biomarkers; Catecholamines; Endothelium, Vascular; Female; H | 1992 |
Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairment.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Endothelins; Female; Humans; Kidney; Pre-Eclampsia; P | 1992 |
Changes in plasmaconcentration of ANP and aldosterone in normal pregnancy and pregnancy complicated by pre-eclampsia.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy T | 1991 |
Ratio between aldosterone and atrial natriuretic peptide in pregnancy.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Natriuresis; Pre-Eclampsia; Pregnancy | 1989 |
Aldosterone, kallikrein, kininase I and II in normal and hypertension complicated pregnancy.
Topics: Aldosterone; Carboxypeptidases; Female; Humans; Hypertension; Kallikreins; Lysine Carboxypeptidase; | 1989 |
[Dopaminergic control of aldosterone and prolactin secretion during normal pregnancy and toxemia of pregnancy].
Topics: Aldosterone; Chorionic Gonadotropin; Dopamine; Dopamine Antagonists; Estradiol; Female; Fetal Blood; | 1989 |
A ouabain-displacing factor in normal pregnancy, pregnancy-induced hypertension and pre-eclampsia.
Topics: Adult; Aldosterone; Cardenolides; Catecholamines; Digoxin; Female; Humans; Hypertension; Natriuretic | 1988 |
Aldosterone is secreted intermittently during pregnancy.
Topics: Aldosterone; Circadian Rhythm; Female; Glucocorticoids; Half-Life; Humans; Pre-Eclampsia; Pregnancy; | 1989 |
Circadian rhythm of plasma atrial natriuretic peptide, aldosterone, and blood pressure during the third trimester in normal and preeclamptic pregnancies.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Circadian Rhythm; Female; Humans; Pre | 1988 |
[Endocrine changes induced by water immersion in women with normal pregnancy and pregnancy complicated by EPH gestosis. I. Effect of water immersion on changes in the renin-angiotensin-aldosterone system in normal pregnancy and EPH gestosis].
Topics: Aldosterone; Angiotensin II; Female; Humans; Immersion; Pre-Eclampsia; Pregnancy; Renin; Temperature | 1988 |
[Hormonal studies of women with a normal pregnancy and in EPH gestosis].
Topics: Adult; Aldosterone; Estradiol; Female; Hormones; Humans; Hydrocortisone; Pre-Eclampsia; Pregnancy; P | 1988 |
Adrenaline and preeclampsia.
Topics: Adult; Aldosterone; Dopamine; Epinephrine; Female; Humans; Pre-Eclampsia; Pregnancy; Renin | 1985 |
Serum aldosterone and plasma renin activity in normal and toxaemic pregnancies.
Topics: Aldosterone; Female; Humans; Pre-Eclampsia; Pregnancy; Renin | 1985 |
The osmoregulatory system and the renin-angiotensin-aldosterone system in pre-eclampsia and normotensive pregnancy.
Topics: Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Body Water; Female; Humans; Osmol | 1985 |
Progress in pre-eclampsia.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hydrocortisone; Pre-Eclampsia; Pregnancy; Renin | 1973 |
[Activity of renin/angiotensin system and secretion of aldosterone during pregnancy].
Topics: Aldosterone; Amniotic Fluid; Angiotensin II; Animals; Blood Volume; Female; Humans; Hyperaldosteroni | 1966 |
The pill, hypertension, and the toxemias of pregnancy.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Edema; Estrogens; Female; Humans; Hypernatremia; | 1971 |
Plasma cortisol and adrenocorticotrophic hormone in normal men and non-pregnant women, normal pregnant women and women with pre-eclampsia.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood; Cesarean Section; Circadian | 1972 |
An essay: prostaglandins and toxemia of pregnancy.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cats; Dogs; Female; Humans; Ischemia; Kidney; | 1973 |
[Metabolism of water and sodium during normal pregnancy and pregnancy toxemia].
Topics: Aldosterone; Angiotensin II; Female; Humans; Pre-Eclampsia; Pregnancy; Renin; Sodium; Uric Acid; Vas | 1972 |
Renal function in pregnancy.
Topics: Aldosterone; Angiotensin II; Catecholamines; Estrogens; Female; Glomerular Filtration Rate; Glycosur | 1972 |
[Pregnancy toxemia. Recent data].
Topics: Aldosterone; Angiotensin II; Disseminated Intravascular Coagulation; Estriol; Female; Fetal Death; F | 1974 |
[Nephrologic aspects of late gestosis (author's transl)].
Topics: Aldosterone; Edema; Female; Hemodynamics; Humans; Hypertension; Kidney Diseases; Pre-Eclampsia; Preg | 1974 |
[Pharmacological and clinical bases for the use of diuretics in pregnancy].
Topics: Adult; Aldosterone; Blood Pressure; Carbohydrate Metabolism; Diuretics; Edema; Female; Fetus; Hormon | 1971 |
[The importance of aldosterone in the pathogenesis of late toxemias of pregnancy].
Topics: Adult; Aldosterone; Female; Humans; Potassium; Pre-Eclampsia; Pregnancy; Sodium | 1971 |
[Aldosterone excretion in normal pregnancy and in late toxemia of pregnancy (literature review)].
Topics: Adrenal Glands; Aldosterone; Cortisone; Female; Humans; Hydrocortisone; Pre-Eclampsia; Pregnancy | 1969 |
[Day- and night-rhythm of alterations of body-weight and electrolyte excretion in physiologic pregnancy and in late toxemia].
Topics: Aldosterone; Blood Volume; Body Weight; Diuresis; Female; Glomerular Filtration Rate; Humans; Postur | 1969 |
The effects of progesterone on the responses of the cardiovascular system to intravenous infusions of aldosterone.
Topics: Aldosterone; Animals; Blood Pressure; Contraceptives, Oral; Drug Synergism; Female; Femoral Artery; | 1970 |
[Treatment of late pregnancy toxemias with aldactone].
Topics: Adolescent; Adult; Aldosterone; Colorimetry; Female; Humans; Potassium; Pre-Eclampsia; Pregnancy; So | 1971 |
[Aldosterone and electrolyte metabolism in normal and pathological pregnancy].
Topics: Aldosterone; Female; Humans; Natriuresis; Potassium; Pre-Eclampsia; Pregnancy; Pregnancy Complicatio | 1971 |
[Aldosterone concentrations in the urine and plasma of normal and pathological pregnancies].
Topics: Adult; Aldosterone; Edema; Female; Humans; Pre-Eclampsia; Pregnancy; Water-Electrolyte Balance | 1967 |
[Excretion dynamics of aldosterone and potassium and sodium content in blood plasma and urine in early pregnancy toxicoses].
Topics: Aldosterone; Female; Humans; Potassium; Pre-Eclampsia; Pregnancy; Sodium | 1968 |
[Changes in aldosterone at the time of utero-renal reflex and pregnancy].
Topics: Adult; Aldosterone; Animals; Female; Gestational Age; Humans; Kidney; Potassium; Pre-Eclampsia; Preg | 1968 |
Aldosterone secretion rates in abnormal pregnancy.
Topics: Adrenal Glands; Aldosterone; Female; Fetal Death; Humans; Pre-Eclampsia; Pregnancy; Progesterone; Ur | 1965 |