Page last updated: 2024-11-07

aldosterone and Dyspnea

aldosterone has been researched along with Dyspnea in 4 studies

Dyspnea: Difficult or labored breathing.

Research Excerpts

ExcerptRelevanceReference
" In addition, the patient's BP decreased, proteinuria was reduced, diuretics could be discontinued, and his calcium channel blocker dosage was decreased."5.51Successful Depressor Effect Concomitant with Complete Normalization of High Renin and Aldosterone Profile by Percutaneous Transluminal Renal Angioplasty in a Patient with Acute Exacerbated Heart Failure with Preserved Ejection Fraction. ( Okamura, K; Shirai, K; Takamiya, Y; Urata, H, 2019)
"Furosemide remains the drug of choice for patients with the transurethral resection syndrome."5.06Furosemide-induced disturbances of renal function in patients undergoing TURP. ( Deshon, GE; Donatucci, CF; Hunt, M; Wade, CE, 1990)
" In addition, the patient's BP decreased, proteinuria was reduced, diuretics could be discontinued, and his calcium channel blocker dosage was decreased."1.51Successful Depressor Effect Concomitant with Complete Normalization of High Renin and Aldosterone Profile by Percutaneous Transluminal Renal Angioplasty in a Patient with Acute Exacerbated Heart Failure with Preserved Ejection Fraction. ( Okamura, K; Shirai, K; Takamiya, Y; Urata, H, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takamiya, Y1
Okamura, K1
Shirai, K1
Urata, H1
Boonen, L1
Verbrugge, FH1
Nijst, P1
Noyens, P1
De Vusser, P1
Verhaert, D1
Van Lierde, J1
Vrolix, M1
Dupont, M1
Mullens, W1
Oster, JR1
Perez, GO1
Rosen, MS1
Donatucci, CF1
Deshon, GE1
Wade, CE1
Hunt, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diuretic Efficiency in Patients With Stable Heart Failure: Ion Excretion Capacity of the Kidneys (DIPSTICK) Study[NCT02288819]50 participants (Actual)Interventional2014-09-30Terminated (stopped due to Slow recruitment and a lack of funding to complete further follow-up)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

All-cause Mortality

(NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

New York Heart Association (NYHA) Functional Class

"NYHA class is a semi-quantitative measurement of functional capacity on a scale from 1 to 4:~No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, dyspnea (shortness of breath).~Slight limitation of physical activity. Comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea (shortness of breath).~Marked limitation of physical activity. Comfortable at rest. Less than ordinary activity causes fatigue, palpitation, or dyspnea.~Unable to carry on any physical activity without discomfort. Symptoms of heart failure at rest. If any physical activity is undertaken, discomfort increases.~For the purpose of this outcome parameter, the patient is contacted by phone 30 days after baseline and NYHA functional class is assessed by a study investigator." (NCT02288819)
Timeframe: 30 days after baseline

Interventionunits on a scale from 1 to 4 (Mean)
Loop Diuretic Downtitration1.41

Number of Participants Rehospitalized for Heart Failure

Unplanned hospital admission for symptoms of congestion and/or low output heart failure requiring either intravenous therapy and/or increase of oral diuretics. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

Number of Participants Requiring a Dose Increase in Loop Diuretics

Dose increase of oral maintenance therapy with loop diuretics compared to the final dose achieved in the study 7 days after baseline. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

Number of Participants With Successful Downtitration of Loop Diuretics (no Weight Increase >1,5 kg)

After baseline evaluation, loop diuretics are temporarily downtitrated or stopped for 7 consecutive days. The patient is instructed to measure his/her weight in the morning of these days, immediately after waking up, on the same balance. In case of weight increase >1,5 kg, the original dose of diuretics is restored. To check this, patients are contacted by phone after 3 and 7 days. If the patient has not gained >1,5 kg of weight after 7 days, loop diuretics are considered to be successfully downtitrated. (NCT02288819)
Timeframe: 7 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration37

Self-reported Lower Leg Edema

The patient is contacted by phone 30 days after baseline and asked for self-reported presence of lower leg edema. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

Self-reported Orthopnea

The patient is contacted by phone 30 days after baseline and asked for self-reported orthopnea. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration5

Weight Change

Weight change [kg] 30 days after baseline compared to weight 7 days after baseline (after achieving the final dose of loop diuretics). (NCT02288819)
Timeframe: 30 days after baseline

Interventionkg (Mean)
Loop Diuretic Downtitration-0.261

Weight Change

Weight change [kg] 7 days after baseline compared to baseline weight. (NCT02288819)
Timeframe: 7 days after baseline

Interventionkg (Mean)
Loop Diuretic Downtitration0.502

Trials

1 trial available for aldosterone and Dyspnea

ArticleYear
Furosemide-induced disturbances of renal function in patients undergoing TURP.
    Urology, 1990, Volume: 35, Issue:4

    Topics: Aged; Aldosterone; Chlorides; Creatinine; Diuresis; Dyspnea; Furosemide; Humans; Hyponatremia; Male;

1990

Other Studies

3 other studies available for aldosterone and Dyspnea

ArticleYear
Successful Depressor Effect Concomitant with Complete Normalization of High Renin and Aldosterone Profile by Percutaneous Transluminal Renal Angioplasty in a Patient with Acute Exacerbated Heart Failure with Preserved Ejection Fraction.
    The American journal of case reports, 2019, Nov-16, Volume: 20

    Topics: Aldosterone; Angioplasty; Dyspnea; Heart Failure; Humans; Hypertension, Renovascular; Male; Middle A

2019
Subclinical volume overload in stable outpatients with chronic heart failure.
    Acta cardiologica, 2016, Volume: 71, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Asymptomatic Disease

2016
Hyporeninemic hypoaldosteronism after chronic sodium bicarbonate abuse.
    Archives of internal medicine, 1976, Volume: 136, Issue:10

    Topics: Aldosterone; Bicarbonates; Dose-Response Relationship, Drug; Dyspnea; Humans; Hyperkalemia; Hyponatr

1976