aldosterone has been researched along with Coronary Artery Disease in 26 studies
Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Non-culprit intermediate coronary atherosclerosis was assessed on intravascular ultrasound." | 6.77 | Effects of valsartan, an angiotensin II receptor blocker, on coronary atherosclerosis in patients with acute myocardial infarction who receive an angiotensin-converting enzyme inhibitor. ( Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kusama, I; Morita, S; Nozawa, N; Okuda, J; Ozaki, H; Tsukahara, K; Umemura, S; Yano, H, 2012) |
| "Two large trials in heart failure have clearly demonstrated that blocking aldosterone improves mortality and that this benefit occurs over and above standard therapy with angiotensin-converting enzyme (ACE) inhibitors." | 6.43 | Aldosterone blockade over and above ACE-inhibitors in patients with coronary artery disease but without heart failure. ( Pringle, S; Shah, NC; Struthers, A, 2006) |
| "Concern about hyperkalemia is thought to contribute to this lack of evidence-based therapy." | 5.91 | Outcomes in patients with cardiometabolic disease who develop hyperkalemia while treated with a renin-angiotensin-aldosterone system inhibitor. ( Johnson, M; McMahon, G; Morrison, FJ; Su, M; Turchin, A, 2023) |
| "Aldosterone plays a key role in maintaining the homeostasis of the whole organism." | 5.48 | Aldosterone modulates blood homocysteine and cholesterol in coronary artery disease patients - a possible impact on atherothrombosis? ( Glowacki, R; Karolczak, K; Kubalczyk, P; Pietruszynski, R; Watala, C, 2018) |
| "Non-culprit intermediate coronary atherosclerosis was assessed on intravascular ultrasound." | 2.77 | Effects of valsartan, an angiotensin II receptor blocker, on coronary atherosclerosis in patients with acute myocardial infarction who receive an angiotensin-converting enzyme inhibitor. ( Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kusama, I; Morita, S; Nozawa, N; Okuda, J; Ozaki, H; Tsukahara, K; Umemura, S; Yano, H, 2012) |
| "Two large trials in heart failure have clearly demonstrated that blocking aldosterone improves mortality and that this benefit occurs over and above standard therapy with angiotensin-converting enzyme (ACE) inhibitors." | 2.43 | Aldosterone blockade over and above ACE-inhibitors in patients with coronary artery disease but without heart failure. ( Pringle, S; Shah, NC; Struthers, A, 2006) |
| "Concern about hyperkalemia is thought to contribute to this lack of evidence-based therapy." | 1.91 | Outcomes in patients with cardiometabolic disease who develop hyperkalemia while treated with a renin-angiotensin-aldosterone system inhibitor. ( Johnson, M; McMahon, G; Morrison, FJ; Su, M; Turchin, A, 2023) |
| "Aldosterone is a steroid hormone regulating fluid and electrolyte homeostasis and is known to increase the risk of atherosclerosis." | 1.56 | Serum Aldosterone Concentration, Blood Pressure, and Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis. ( Allison, M; Goldwater, D; Inoue, K; Kestenbaum, BR; Seeman, T; Watson, KE, 2020) |
| "Aldosterone plays a key role in maintaining the homeostasis of the whole organism." | 1.48 | Aldosterone modulates blood homocysteine and cholesterol in coronary artery disease patients - a possible impact on atherothrombosis? ( Glowacki, R; Karolczak, K; Kubalczyk, P; Pietruszynski, R; Watala, C, 2018) |
| "Spironolactone treatment decreased PAI-1 immunoreactivity and reduced in a dose-dependent fashion cardiac and renal damage." | 1.32 | Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury. ( Adler, GK; Jonasson, L; Martinez-Vasquez, D; Mukasa, K; Oestreicher, EM; Roubsanthisuk, W; Stone, JR, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 7 (26.92) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, M | 1 |
| Morrison, FJ | 1 |
| McMahon, G | 1 |
| Su, M | 1 |
| Turchin, A | 1 |
| Williams, C | 1 |
| Han, D | 1 |
| Takagi, H | 1 |
| Fordyce, CB | 1 |
| Sellers, S | 1 |
| Blanke, P | 1 |
| Lin, FY | 1 |
| Shaw, LJ | 1 |
| Lee, SE | 1 |
| Andreini, D | 1 |
| Al-Mallah, MH | 1 |
| Budoff, MJ | 1 |
| Cademartiri, F | 1 |
| Chinnaiyan, K | 1 |
| Choi, JH | 1 |
| Conte, E | 1 |
| Marques, H | 1 |
| de Araújo Gonçalves, P | 1 |
| Gottlieb, I | 1 |
| Hadamitzky, M | 1 |
| Maffei, E | 1 |
| Pontone, G | 1 |
| Shin, S | 1 |
| Kim, YJ | 1 |
| Lee, BK | 1 |
| Chun, EJ | 1 |
| Sung, JM | 1 |
| Virmani, R | 1 |
| Samady, H | 1 |
| Stone, PH | 1 |
| Berman, DS | 1 |
| Narula, J | 1 |
| Bax, JJ | 1 |
| Leipsic, JA | 1 |
| Chang, HJ | 1 |
| Unkart, JT | 1 |
| Allison, MA | 1 |
| Abdelmalek, JA | 1 |
| Jenny, NS | 1 |
| McClelland, RL | 1 |
| Budoff, M | 1 |
| Ix, JH | 1 |
| Rifkin, DE | 1 |
| Inoue, K | 1 |
| Goldwater, D | 1 |
| Allison, M | 1 |
| Seeman, T | 1 |
| Kestenbaum, BR | 1 |
| Watson, KE | 1 |
| Grübler, MR | 1 |
| Delgado, G | 1 |
| Kleber, M | 1 |
| Hartaigh, BÓ | 1 |
| de Boer, RA | 1 |
| Verheyen, N | 1 |
| Keppel, M | 1 |
| Schmid, J | 1 |
| Siontis, GC | 1 |
| Räber, L | 1 |
| Pieske, B | 1 |
| Pilz, S | 1 |
| Tomaschitz, A | 1 |
| März, W | 1 |
| Srinivasa, S | 1 |
| Thomas, TS | 1 |
| Feldpausch, MN | 1 |
| Adler, GK | 2 |
| Grinspoon, SK | 1 |
| Goodwill, AG | 1 |
| Baker, HE | 1 |
| Dick, GM | 1 |
| McCallinhart, PE | 1 |
| Bailey, CA | 1 |
| Brown, SM | 1 |
| Man, JJ | 1 |
| Tharp, DL | 1 |
| Clark, HE | 1 |
| Blaettner, BS | 1 |
| Jaffe, IZ | 1 |
| Bowles, DK | 1 |
| Trask, AJ | 1 |
| Tune, JD | 1 |
| Bender, SB | 1 |
| Karolczak, K | 1 |
| Kubalczyk, P | 1 |
| Glowacki, R | 1 |
| Pietruszynski, R | 1 |
| Watala, C | 1 |
| Cannone, V | 1 |
| Buglioni, A | 1 |
| Sangaralingham, SJ | 1 |
| Scott, C | 1 |
| Bailey, KR | 1 |
| Rodeheffer, R | 1 |
| Redfield, MM | 1 |
| Sarzani, R | 1 |
| Burnett, JC | 1 |
| Jia, EZ | 1 |
| Chen, ZH | 1 |
| An, FH | 1 |
| Li, LH | 1 |
| Guo, CY | 1 |
| Gu, Y | 1 |
| Liu, Z | 1 |
| Li, ZY | 1 |
| Zhu, TB | 1 |
| Wang, LS | 1 |
| Li, CJ | 1 |
| Kong, XQ | 1 |
| Ma, WZ | 1 |
| Yang, ZJ | 1 |
| Lee, MY | 1 |
| Lai, WT | 1 |
| Xanthakis, V | 1 |
| Enserro, DM | 1 |
| Larson, MG | 1 |
| Wollert, KC | 1 |
| Januzzi, JL | 1 |
| Levy, D | 1 |
| Aragam, J | 1 |
| Benjamin, EJ | 1 |
| Cheng, S | 1 |
| Wang, TJ | 1 |
| Mitchell, GF | 1 |
| Vasan, RS | 1 |
| Adamzik, M | 1 |
| Frey, UH | 1 |
| Bitzer, K | 1 |
| Jakob, H | 1 |
| Baba, HA | 1 |
| Schmieder, RE | 1 |
| Schneider, MP | 1 |
| Heusch, G | 1 |
| Peters, J | 1 |
| Siffert, W | 1 |
| Ivanes, F | 1 |
| Susen, S | 1 |
| Mouquet, F | 1 |
| Pigny, P | 1 |
| Cuilleret, F | 1 |
| Sautière, K | 1 |
| Collet, JP | 1 |
| Beygui, F | 2 |
| Hennache, B | 1 |
| Ennezat, PV | 1 |
| Juthier, F | 1 |
| Richard, F | 1 |
| Dallongeville, J | 1 |
| Hillaert, MA | 2 |
| Doevendans, PA | 2 |
| Jude, B | 1 |
| Bertrand, M | 1 |
| Montalescot, G | 2 |
| Van Belle, E | 2 |
| Pitt, B | 1 |
| Yano, H | 1 |
| Hibi, K | 1 |
| Nozawa, N | 1 |
| Ozaki, H | 1 |
| Kusama, I | 1 |
| Ebina, T | 1 |
| Kosuge, M | 1 |
| Tsukahara, K | 1 |
| Okuda, J | 1 |
| Morita, S | 1 |
| Umemura, S | 1 |
| Kimura, K | 1 |
| Lentjes, EG | 1 |
| Kemperman, H | 1 |
| van der Graaf, Y | 1 |
| Nathoe, HM | 1 |
| Wassink, AM | 1 |
| Donner, KM | 1 |
| Hiltunen, TP | 1 |
| Jänne, OA | 1 |
| Sane, T | 1 |
| Kontula, K | 1 |
| Mezősi, E | 1 |
| Bajnok, L | 1 |
| Tóth, K | 1 |
| Oestreicher, EM | 1 |
| Martinez-Vasquez, D | 1 |
| Stone, JR | 1 |
| Jonasson, L | 1 |
| Roubsanthisuk, W | 1 |
| Mukasa, K | 1 |
| Kürüm, T | 1 |
| Yüksel, M | 1 |
| Ozbay, G | 1 |
| Söyük, S | 1 |
| Türe, M | 1 |
| Donderski, R | 1 |
| Grajewska, M | 1 |
| Manitius, J | 1 |
| Sezai, A | 1 |
| Hata, M | 1 |
| Wakui, S | 1 |
| Shiono, M | 1 |
| Negishi, N | 1 |
| Kasamaki, Y | 1 |
| Saito, S | 1 |
| Kato, J | 1 |
| Minami, K | 1 |
| Shah, NC | 1 |
| Pringle, S | 1 |
| Struthers, A | 1 |
| Krakoff, LR | 1 |
| Struthers, AD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Mineralcorticoid Recept Antagonist on Cardiovascular Disease in Patients With Hypertension and Hyperaldosteronemia：A Multicenter Randomized Controlled Study[NCT05688579] | Phase 4 | 8,000 participants (Anticipated) | Interventional | 2023-04-16 | Enrolling by invitation | ||
| A Safety and Feasibility Study of Water-only Fasting and Refeeding for Treatment of Stage 1 and 2 Hypertensive Patients[NCT04515095] | 30 participants (Actual) | Interventional | 2020-08-16 | Completed | |||
| Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055] | Phase 4 | 75 participants (Anticipated) | Interventional | 2023-08-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for aldosterone and Coronary Artery Disease
| Article | Year |
|---|---|
Coronary Vasculature and Myocardial Structure in HIV: Physiologic Insights From the Renin-Angiotensin-Aldosterone System.
Topics: Aldosterone; Cardiovascular Diseases; Coronary Artery Disease; HIV; HIV Infections; Humans; Myocardi | 2021 |
[The heart as an endocrine organ].
Topics: Adipocytes; Adipokines; Aldosterone; Biomarkers; Cardiomegaly; Coronary Artery Disease; Cytokines; H | 2012 |
[The role of aldosterone in cardiovascular alterations in patients with chronic kidney disease].
Topics: Aldosterone; Coronary Artery Disease; Heart Failure; Humans; Kidney Failure, Chronic | 2006 |
Aldosterone blockade over and above ACE-inhibitors in patients with coronary artery disease but without heart failure.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2006 |
Aldosterone-induced vasculopathy: a new reversible cause of cardiac death.
Topics: Aldosterone; Coronary Artery Disease; Death, Sudden, Cardiac; Humans | 2001 |
2 trials available for aldosterone and Coronary Artery Disease
| Article | Year |
|---|---|
Effects of valsartan, an angiotensin II receptor blocker, on coronary atherosclerosis in patients with acute myocardial infarction who receive an angiotensin-converting enzyme inhibitor.
Topics: Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors | 2012 |
Efficacy of low-dose continuous infusion of alpha-human atrial natriuretic peptide (hANP) during cardiac surgery: possibility of postoperative left ventricular remodeling effect.
Topics: Aged; Aldosterone; Arrhythmias, Cardiac; Atrial Natriuretic Factor; Blood Pressure; Cardiopulmonary | 2006 |
19 other studies available for aldosterone and Coronary Artery Disease
| Article | Year |
|---|---|
Outcomes in patients with cardiometabolic disease who develop hyperkalemia while treated with a renin-angiotensin-aldosterone system inhibitor.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Arte | 2023 |
Effects of renin-angiotensin-aldosterone-system inhibitors on coronary atherosclerotic plaques: The PARADIGM registry.
Topics: Aldosterone; Angiotensins; Computed Tomography Angiography; Coronary Angiography; Coronary Artery Di | 2023 |
Relation of Plasma Renin Activity to Subclinical Peripheral and Coronary Artery Disease (from the Multiethnic Study of Atherosclerosis).
Topics: Aldosterone; Ankle Brachial Index; Atherosclerosis; Biomarkers; Coronary Artery Disease; Female; Hum | 2020 |
Serum Aldosterone Concentration, Blood Pressure, and Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis.
Topics: Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Calcinosis; Calcium; Computed Tomography Angio | 2020 |
Effect of Galectin 3 on Aldosterone-Associated Risk of Cardiovascular Mortality in Patients Undergoing Coronary Angiography.
Topics: Aged; Aldosterone; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Female; F | 2020 |
Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in K
Topics: Aldosterone; Animals; Arterioles; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; D | 2021 |
Aldosterone modulates blood homocysteine and cholesterol in coronary artery disease patients - a possible impact on atherothrombosis?
Topics: Adrenal Glands; Aged; Aldosterone; Animals; Arachidonic Acid; Cholesterol; Collagen; Coronary Artery | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Relationship of renin-angiotensin-aldosterone system polymorphisms and phenotypes to mortality in Chinese coronary atherosclerosis patients.
Topics: Aged; Aldosterone; Alleles; Angiotensin II; Asian People; China; Coronary Artery Disease; Female; Fo | 2014 |
Plasma renin level and aldosterone to renin ratio are associated with presence of carotid plaques in patients with stable coronary artery disease.
Topics: Aged; Aldosterone; Carotid Intima-Media Thickness; Carotid Stenosis; Coronary Artery Disease; Female | 2015 |
Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community.
Topics: Adult; Aged; Aldosterone; C-Reactive Protein; Coronary Artery Disease; Diabetes Mellitus; Female; He | 2016 |
A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men.
Topics: Adult; Aged; Aldosterone; Alleles; Angiotensin II; Aquaporin 5; Blood Pressure; Case-Control Studies | 2008 |
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure.
Topics: Age Factors; Aged; Aldosterone; Angioplasty, Balloon, Coronary; Body Mass Index; Brain Ischemia; C-R | 2012 |
Plasma aldosterone levels in patients with coronary artery disease without heart failure or myocardial infarction: implications for pathophsiology, prognosis, and therapy.
Topics: Aldosterone; Coronary Artery Disease; Female; Humans; Male | 2012 |
Aldosterone, atherosclerosis and vascular events in patients with stable coronary artery disease.
Topics: Aged; Aldosterone; Atherosclerosis; Biomarkers; Cohort Studies; Coronary Artery Disease; Female; Fol | 2013 |
Generalized glucocorticoid resistance caused by a novel two-nucleotide deletion in the hormone-binding domain of the glucocorticoid receptor gene NR3C1.
Topics: Adult; Aldosterone; Animals; Base Sequence; Coronary Artery Disease; COS Cells; Female; Frameshift M | 2013 |
Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury.
Topics: Aldosterone; Angiotensin II; Animals; Cardiovascular Diseases; Coronary Artery Disease; Disease Mode | 2003 |
Relationship with plasma neurohormones and dyssynchrony detected by Doppler echocardiography in patients undergoing permanent pacemaker implantation.
Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Flow Velocity; Cardiac Pacing, Artif | 2003 |
Is aldosterone a pro-arrhythmic hormone?
Topics: Aldosterone; Arrhythmias, Cardiac; Coronary Artery Disease; Humans; Peptide Fragments; Procollagen; | 2007 |