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aldosterone and Compensatory Hyperinsulinemia

aldosterone has been researched along with Compensatory Hyperinsulinemia in 17 studies

Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.

Research Excerpts

ExcerptRelevanceReference
"Chronic HFD exposure further promoted hyperinsulinemia in ASKO mice that contributed to visceral fat accumulation accompanied by reduced lipolysis, thermogenic reprogramming, and the absence of weight-gain-related EE increases."5.48Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity. ( Faresse, N; Henneberg, M; Langhans, W; Liao, WH; Odermatt, A; Pacheco Lopez, G; Steuer, AE; Suendermann, C, 2018)
"To measure the effects of hyperinsulinemia on serum electrolyte status and associated hormones, and on serum free fatty acid (FFA) concentrations, in patients with essential hypertension."5.31Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension. ( Haenni, A; Lind, L; Lithell, H; Reneland, R, 2001)
"These results demonstrates that hypertension and insulin resistance induced by COC is associated with increased cardiac RAS and PAI-1 gene expression, which is likely to be through corticosterone-dependent but not aldosterone-dependent mechanism."3.85Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. ( Kim, IK; Olatunji, LA; Seok, YM; Usman, TO, 2017)
" Therefore, food intake and weight gain were measured in obese adrenalectomized VMH-lesioned rats given continuous infusion of various doses of either a type I-receptor agonist (aldosterone), a type II-receptor agonist (RU-28362), or several combination doses."3.69Relative contribution of type I and II corticosterone receptors in VMH lesion-induced obesity and hyperinsulinemia. ( Devenport, LD; Stith, RD; Thomas, TL, 1994)
"In both groups, hyperinsulinemia caused a decrease in blood volume (0."2.70Defective regulation and action of atrial natriuretic peptide in type 2 diabetes. ( Baldi, S; Catalano, C; Ferrannini, E; Nannipieri, M; Prontera, T; Seghieri, G, 2002)
"Obesity is strongly associated with hypertension and cardiovascular disease."2.43Obesity-associated hypertension: new insights into mechanisms. ( Correia, ML; Haynes, WG; Mark, AL; Rahmouni, K, 2005)
"Chronic HFD exposure further promoted hyperinsulinemia in ASKO mice that contributed to visceral fat accumulation accompanied by reduced lipolysis, thermogenic reprogramming, and the absence of weight-gain-related EE increases."1.48Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity. ( Faresse, N; Henneberg, M; Langhans, W; Liao, WH; Odermatt, A; Pacheco Lopez, G; Steuer, AE; Suendermann, C, 2018)
"(1) Within a normotensive range, hyperinsulinemia and/or insulin resistance influence daily BP variation more than obesity does, suggesting a pivotal role of insulin on BP control in PCOS; (2) altered insulinemic state and ABPM-derived higher nighttime BP and HR may represent early markers to identify PCOS subjects prone to high cardiovascular risk."1.46Hyperinsulinemia and obese phenotype differently influence blood pressure in young normotensive patients with polycystic ovary syndrome. ( Azzolini, S; Bleve, L; Cà, AD; Fallo, F; Maffei, P; Mioni, R; Turra, J; Vettor, R; Xamin, N, 2017)
"To measure the effects of hyperinsulinemia on serum electrolyte status and associated hormones, and on serum free fatty acid (FFA) concentrations, in patients with essential hypertension."1.31Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension. ( Haenni, A; Lind, L; Lithell, H; Reneland, R, 2001)
"Finally, the magnitude of hyperinsulinemia correlated directly with systolic (r = 0."1.28Changes in blood pressure, plasma triglyceride and aldosterone concentration, and red cell cation concentration in patients with hyperinsulinemia. ( Battezzati, M; Massarino, F; Mazza, S; Pontremoli, R; Reaven, GM; Tixianello, A; Zavaroni, I, 1991)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's6 (35.29)18.2507
2000's7 (41.18)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liao, WH1
Suendermann, C1
Steuer, AE1
Pacheco Lopez, G1
Odermatt, A1
Faresse, N1
Henneberg, M1
Langhans, W1
Olatunji, LA1
Usman, TO1
Seok, YM1
Kim, IK1
Mioni, R1
Cà, AD1
Turra, J1
Azzolini, S1
Xamin, N1
Bleve, L1
Maffei, P1
Vettor, R1
Fallo, F1
Rahmouni, K1
Correia, ML1
Haynes, WG1
Mark, AL1
Colussi, G1
Catena, C1
Lapenna, R1
Nadalini, E1
Chiuch, A1
Sechi, LA1
Perciaccante, A1
Fiorentini, A1
Valente, R1
Di Stefano, A1
Tubani, L1
Thomas, TL1
Devenport, LD1
Stith, RD1
Inoue, J1
Cappuccio, FP1
Sagnella, GA1
Markandu, ND1
Folkerd, EJ1
Sampson, B1
Miller, MA1
Blackwood, AM1
MacGregor, GA1
Petrie, JR1
Morris, AD1
Ueda, S1
Small, M1
Donnelly, R1
Connell, JM1
Elliott, HL1
Haenni, A1
Reneland, R1
Lind, L2
Lithell, H2
Andronico, G1
Cottone, S1
Mangano, MT1
Ferraro-Mortellaro, R1
Baiardi, G1
Grassi, N1
Ferrara, L1
Mulé, G1
Cerasola, G1
Nannipieri, M1
Seghieri, G1
Catalano, C1
Prontera, T1
Baldi, S1
Ferrannini, E1
Resnick, LM1
Wide, L1
Ljunghall, S1
Pontremoli, R1
Zavaroni, I1
Mazza, S1
Battezzati, M1
Massarino, F1
Tixianello, A1
Reaven, GM1
Ferriss, JB1
Rastogi, KS1
Campbell, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Aldosterone on Sympathetic Nerve Activity and Insulin Sensitivity[NCT02102243]Phase 40 participants (Actual)Interventional2010-11-30Withdrawn (stopped due to No longer interested in study topic)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aldosterone and Compensatory Hyperinsulinemia

ArticleYear
Obesity-associated hypertension: new insights into mechanisms.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:1

    Topics: Adiponectin; Aldosterone; Animals; Appetite; Endothelium, Vascular; Energy Metabolism; Ghrelin; Huma

2005
Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders.
    The American journal of medicine, 1992, Aug-31, Volume: 93, Issue:2A

    Topics: Aldosterone; Blood Glucose; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiomegaly; Diabete

1992
The causes of raised blood pressure in insulin-dependent and non-insulin-dependent diabetes.
    Journal of human hypertension, 1991, Volume: 5, Issue:4

    Topics: Aldosterone; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopat

1991

Trials

3 trials available for aldosterone and Compensatory Hyperinsulinemia

ArticleYear
Glucose load and renal sodium handling in mild essential hypertension on different sodium intakes.
    Journal of human hypertension, 1996, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Aldosterone; C-Peptide; Cross-Over Studies; Diet, Sodium-Restricted; Double-Blind

1996
Trandolapril does not improve insulin sensitivity in patients with hypertension and type 2 diabetes: a double-blind, placebo-controlled crossover trial.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; C

2000
Defective regulation and action of atrial natriuretic peptide in type 2 diabetes.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2002, Volume: 34, Issue:5

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Glucose; Blood Volume; Body Mass Index; D

2002

Other Studies

11 other studies available for aldosterone and Compensatory Hyperinsulinemia

ArticleYear
Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.
    JCI insight, 2018, 07-26, Volume: 3, Issue:14

    Topics: Adipocytes; Aldosterone; Animals; Cytochrome P-450 CYP11B2; Diet, High-Fat; Disease Models, Animal;

2018
Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder.
    Archives of physiology and biochemistry, 2017, Volume: 123, Issue:1

    Topics: Aldosterone; Animals; Ataxia Telangiectasia Mutated Proteins; Cardiovascular Diseases; Contraceptive

2017
Hyperinsulinemia and obese phenotype differently influence blood pressure in young normotensive patients with polycystic ovary syndrome.
    Endocrine, 2017, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Section

2017
Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients.
    Diabetes care, 2007, Volume: 30, Issue:9

    Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Glucose; Humans; Hyperinsulinism; Hypertension;

2007
Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients: response to Colussi et al.
    Diabetes care, 2007, Volume: 30, Issue:10

    Topics: Aldosterone; Humans; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Reproducibility of

2007
Relative contribution of type I and II corticosterone receptors in VMH lesion-induced obesity and hyperinsulinemia.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: Adrenalectomy; Aldosterone; Androstanols; Animals; Female; Hyperinsulinism; Hyperphagia; Insulin; Ob

1994
Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension.
    Journal of hypertension, 2001, Volume: 19, Issue:1

    Topics: Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium; Disease Progressio

2001
Insulin, renin-aldosterone system and blood pressure in obese people.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2001, Volume: 25, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperinsulinism; Hypert

2001
Metabolic cardiovascular risk factors and the renin-aldosterone system in essential hypertension.
    Journal of human hypertension, 1992, Volume: 6, Issue:1

    Topics: Adult; Aldosterone; Body Mass Index; Cardiovascular Diseases; Cholesterol, HDL; Creatine; Female; Gl

1992
Changes in blood pressure, plasma triglyceride and aldosterone concentration, and red cell cation concentration in patients with hyperinsulinemia.
    American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 1

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cations; Erythrocyte Count; Erythrocytes; Hu

1991
Effect of growth hormone on cortisone-induced hyperinsulinemia and reduction in pancreatic insulin in the mouse.
    Endocrinology, 1970, Volume: 87, Issue:2

    Topics: Adenoma, Islet Cell; Aldosterone; Animals; Blood Glucose; Body Weight; Cortisone; Drug Antagonism; E

1970