aldosterone has been researched along with Cardio-Renal Syndrome in 11 studies
Cardio-Renal Syndrome: Condition where a primary dysfunction of either heart or kidney results in failure of the other organ (e.g., HEART FAILURE with worsening RENAL INSUFFICIENCY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adverse events related to BAY 94-8862 were infrequent and mostly mild." | 2.78 | Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial. ( Filippatos, G; Gheorghiade, M; Kim, SY; Kober, L; Kolkhof, P; Krum, H; Nowack, C; Pitt, B; Ponikowski, P; Zannad, F, 2013) |
| "Heart failure is a complex syndrome that affects almost all organs and systems of the body." | 2.50 | [Organ damage and cardiorenal syndrome in acute heart failure]. ( Casado Cerrada, J; Pérez Calvo, JI, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 5 (45.45) | 2.80 |
| Authors | Studies |
|---|---|
| Junho, CVC | 1 |
| Trentin-Sonoda, M | 1 |
| Panico, K | 1 |
| Dos Santos, RSN | 1 |
| Abrahão, MV | 1 |
| Vernier, ICS | 1 |
| Fürstenau, CR | 1 |
| Carneiro-Ramos, MS | 1 |
| Bakris, GL | 1 |
| Jaisser, F | 1 |
| Han, Y | 3 |
| Xian, Y | 3 |
| Gao, X | 3 |
| Qiang, P | 3 |
| Hao, J | 3 |
| Yang, F | 3 |
| Shimosawa, T | 3 |
| Chang, Y | 3 |
| Xu, Q | 3 |
| Yamashita, K | 1 |
| Ito, K | 1 |
| Endo, J | 1 |
| Matsuhashi, T | 1 |
| Katsumata, Y | 1 |
| Yamamoto, T | 1 |
| Shirakawa, K | 1 |
| Isobe, S | 1 |
| Kataoka, M | 1 |
| Yoshida, N | 1 |
| Goto, S | 1 |
| Moriyama, H | 1 |
| Kitakata, H | 1 |
| Mitani, F | 1 |
| Fukuda, K | 1 |
| Goda, N | 1 |
| Ichihara, A | 1 |
| Sano, M | 1 |
| Valero-Muñoz, M | 1 |
| Oh, A | 1 |
| Faudoa, E | 1 |
| Bretón-Romero, R | 1 |
| El Adili, F | 1 |
| Bujor, A | 1 |
| Sam, F | 1 |
| Pitt, B | 2 |
| Kober, L | 1 |
| Ponikowski, P | 1 |
| Gheorghiade, M | 1 |
| Filippatos, G | 1 |
| Krum, H | 1 |
| Nowack, C | 1 |
| Kolkhof, P | 1 |
| Kim, SY | 1 |
| Zannad, F | 1 |
| Casado Cerrada, J | 1 |
| Pérez Calvo, JI | 1 |
| Buglioni, A | 1 |
| Cannone, V | 1 |
| Cataliotti, A | 1 |
| Sangaralingham, SJ | 1 |
| Heublein, DM | 1 |
| Scott, CG | 1 |
| Bailey, KR | 1 |
| Rodeheffer, RJ | 1 |
| Dessì-Fulgheri, P | 1 |
| Sarzani, R | 1 |
| Burnett, JC | 1 |
| Vemulapalli, S | 1 |
| Tyson, CC | 1 |
| Svetkey, LP | 1 |
| Senni, M | 1 |
| D'Elia, E | 1 |
| Emdin, M | 1 |
| Vergaro, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blind, Multi-center Study to Assess Safety and Tolerability of Different Oral Doses of BAY94-8862 in Subjects With Stable Chronic Heart Failure With Left Ventricular Systolic Dysfunction and Mild (Part A) or Moderate (Part B) Chronic [NCT01345656] | Phase 2 | 457 participants (Actual) | Interventional | 2011-05-09 | Completed | ||
| Pathophysiologic and Outcomes Impact of the Relation of Intravascular Volume Expansion to Neuroendocrine-Renal Function Profiles in Chronic Heart Failure - Pathway to More Individualized Therapy[NCT04156854] | 15 participants (Actual) | Interventional | 2020-01-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aldosterone and Cardio-Renal Syndrome
| Article | Year |
|---|---|
Cardiorenal syndrome: long road between kidney and heart.
Topics: Aldosterone; Angiotensins; Cardio-Renal Syndrome; Humans; Kidney; Renin | 2022 |
[Organ damage and cardiorenal syndrome in acute heart failure].
Topics: Aldosterone; Cardiac Output; Cardio-Renal Syndrome; Comorbidity; Endothelium, Vascular; Heart Failur | 2014 |
Apparent treatment-resistant hypertension and chronic kidney disease: another cardiovascular-renal syndrome?
Topics: Aldosterone; Antihypertensive Agents; Blood Volume; Cardio-Renal Syndrome; Coronary Vasospasm; Diure | 2014 |
Biomarkers of Heart Failure with Preserved and Reduced Ejection Fraction.
Topics: Adrenomedullin; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; beta-N-Acetyl-Galactosaminid | 2017 |
1 trial available for aldosterone and Cardio-Renal Syndrome
| Article | Year |
|---|---|
Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial.
Topics: Administration, Oral; Aged; Albuminuria; Aldosterone; Blood Pressure; Cardio-Renal Syndrome; Creatin | 2013 |
6 other studies available for aldosterone and Cardio-Renal Syndrome
| Article | Year |
|---|---|
Aldosterone excess and cardiorenal risk: more common than appreciated.
Topics: Aldosterone; Cardio-Renal Syndrome; Humans; Kidney; Mineralocorticoid Receptor Antagonists | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Topics: Aldosterone; Animals; Cardio-Renal Syndrome; Eplerenone; Fibrosis; Heart Diseases; Macrophages; Myof | 2022 |
Adrenal cortex hypoxia modulates aldosterone production in heart failure.
Topics: Adrenal Cortex; Aldosterone; Animals; Cardio-Renal Syndrome; Catecholamines; Cell Hypoxia; Cell Line | 2020 |
Endothelial-Mesenchymal Transition in Heart Failure With a Preserved Ejection Fraction: Insights Into the Cardiorenal Syndrome.
Topics: Aldosterone; Biomarkers; Cardio-Renal Syndrome; Endothelial Cells; Heart Failure; Humans; Myocardium | 2021 |
Mineralocorticoid receptor antagonists for the treatment of hypertension and the metabolic syndrome.
Topics: Aldosterone; Cardio-Renal Syndrome; Female; Humans; Male; Metabolic Diseases; Natriuretic Peptides | 2015 |
Circulating aldosterone and natriuretic peptides in the general community: relationship to cardiorenal and metabolic disease.
Topics: Aldosterone; Biomarkers; Body Mass Index; Cardio-Renal Syndrome; Female; Humans; Male; Metabolic Dis | 2015 |