Page last updated: 2024-11-07

aldosterone and Calcinosis

aldosterone has been researched along with Calcinosis in 11 studies

Calcinosis: Pathologic deposition of calcium salts in tissues.

Research Excerpts

ExcerptRelevanceReference
"Primary aldosteronism (PA) is the most common type of secondary hypertension, and it is associated with a higher rate of cardiovascular complications."5.72KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma. ( Chang, CC; Chang, YY; Chen, ZW; Chiu, YW; Chou, CH; Huang, JZ; Hung, CS; Kang, VJ; Lee, BC; Liao, CW; Lin, YH; Lin, YL; Pan, CT; Tsai, CH; Wu, VC, 2022)
"Aldosterone (Aldo) promotes proteoglycan synthesis in valve interstitial cells (VICs) from mitral valves via the mineralocorticoid receptor (MR)."5.72Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis. ( Álvarez de la Rosa, D; Álvarez, V; Arrieta, V; Fernández-Celis, A; Gainza, A; Garaikoetxea, M; García-Peña, A; Jaisser, F; Jover, E; López-Andrés, N; Martín-Nuñez, E; Matilla, L; Navarro, A; Sádaba, R, 2022)
"Primary aldosteronism (PA) is the most common type of secondary hypertension, and it is associated with a higher rate of cardiovascular complications."1.72KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma. ( Chang, CC; Chang, YY; Chen, ZW; Chiu, YW; Chou, CH; Huang, JZ; Hung, CS; Kang, VJ; Lee, BC; Liao, CW; Lin, YH; Lin, YL; Pan, CT; Tsai, CH; Wu, VC, 2022)
"Aldosterone (Aldo) promotes proteoglycan synthesis in valve interstitial cells (VICs) from mitral valves via the mineralocorticoid receptor (MR)."1.72Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis. ( Álvarez de la Rosa, D; Álvarez, V; Arrieta, V; Fernández-Celis, A; Gainza, A; Garaikoetxea, M; García-Peña, A; Jaisser, F; Jover, E; López-Andrés, N; Martín-Nuñez, E; Matilla, L; Navarro, A; Sádaba, R, 2022)
"Aldosterone is a steroid hormone regulating fluid and electrolyte homeostasis and is known to increase the risk of atherosclerosis."1.56Serum Aldosterone Concentration, Blood Pressure, and Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis. ( Allison, M; Goldwater, D; Inoue, K; Kestenbaum, BR; Seeman, T; Watson, KE, 2020)
"Out of 100 cases of tumoral primary aldosteronism studied from 1977 to 1987, we observed 4 ACC and 96 Conn's adenomas (CONN)."1.27[Malignant adrenal cortex carcinoma revealed by an isolated picture of primary hyperaldosteronism]. ( Chatellier, G; Corvol, P; Farge, D; Pagny, JY; Plouin, PF, 1988)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Lee, BC1
Kang, VJ1
Pan, CT1
Huang, JZ1
Lin, YL1
Chang, YY1
Tsai, CH1
Chou, CH1
Chen, ZW1
Liao, CW1
Chiu, YW1
Wu, VC1
Hung, CS1
Chang, CC1
Lin, YH1
Matilla, L1
Jover, E1
Garaikoetxea, M1
Martín-Nuñez, E1
Arrieta, V1
García-Peña, A1
Navarro, A1
Fernández-Celis, A1
Gainza, A1
Álvarez, V1
Álvarez de la Rosa, D1
Sádaba, R1
Jaisser, F1
López-Andrés, N1
Inoue, K1
Goldwater, D1
Allison, M1
Seeman, T1
Kestenbaum, BR1
Watson, KE1
Leibrock, CB1
Voelkl, J1
Kohlhofer, U1
Quintanilla-Martinez, L1
Kuro-O, M1
Lang, F1
KRUCK, F1
Jaffe, IZ1
Tintut, Y1
Newfell, BG1
Demer, LL1
Mendelsohn, ME1
de Solís, AJ1
González-Pacheco, FR1
Deudero, JJ1
Neria, F1
Calabia, O1
Fernández-Sánchez, R1
Caramelo, C1
Paillard, J1
Baviera, E1
Agarwal, MK1
Farge, D1
Pagny, JY1
Chatellier, G1
Plouin, PF1
Corvol, P1
Yoshida, M1
Yano, S1
Tsuruta, K1
Ueda, S1
Ikegami, K1
Kelch, RP1
Connors, MH1
Kaplan, SL1
Biglieri, EG1
Grumbach, MM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Mineralcorticoid Recept Antagonist on Cardiovascular Disease in Patients With Hypertension and Hyperaldosteronemia:A Multicenter Randomized Controlled Study[NCT05688579]Phase 48,000 participants (Anticipated)Interventional2023-04-16Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for aldosterone and Calcinosis

ArticleYear
KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Aorta; Calcinosis; G Protein

2022
Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:8

    Topics: Aldosterone; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Female; Fibrosis; Hum

2022
Serum Aldosterone Concentration, Blood Pressure, and Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:1

    Topics: Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Calcinosis; Calcium; Computed Tomography Angio

2020
Bicarbonate-sensitive calcification and lifespan of klotho-deficient mice.
    American journal of physiology. Renal physiology, 2016, Jan-01, Volume: 310, Issue:1

    Topics: Acidosis; Aldosterone; Animals; Calcinosis; Calcitriol; Calcium; Genotype; Glucuronidase; Hyperaldos

2016
[Extrarenal electrolyte shifts after administration of aldosterone].
    Klinische Wochenschrift, 1959, Jun-15, Volume: 37, Issue:12

    Topics: Adrenalectomy; Aldosterone; Calcinosis; Electrolytes; Medical Records; Nephrectomy

1959
Mineralocorticoid receptor activation promotes vascular cell calcification.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Aldosterone; Alkaline Phosphat

2007
[Aldosterone increases in vitro vascular calcification].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2008, Volume: 28, Issue:2

    Topics: Aldosterone; Calcinosis; Cells, Cultured; Humans; Muscle, Smooth, Vascular; Vascular Diseases

2008
Gluco- and mineralocorticoid receptors in human liver and kidney.
    Biochemical medicine, 1980, Volume: 24, Issue:2

    Topics: Adenocarcinoma; Aged; Aldosterone; Animals; Calcinosis; Desoxycorticosterone; Female; Humans; Hydron

1980
[Malignant adrenal cortex carcinoma revealed by an isolated picture of primary hyperaldosteronism].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Adult; Aldosterone; Calcinosis; Female; Human

1988
Aldosterone-producing gigantic adrenocortical adenoma with calcifications and cysts.
    Urology, 1985, Volume: 26, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adult; Aldosterone; Calcinosis; Cysts; Hu

1985
A calcified aldosterone-producing tumor in a hypertensive, normokalemic, prepubertal girl.
    The Journal of pediatrics, 1973, Volume: 83, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Calcinosis; Child; Child Behavior Disorders; Desoxyco

1973