Page last updated: 2024-11-07

aldosterone and Asymptomatic Conditions

aldosterone has been researched along with Asymptomatic Conditions in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Primary aldosteronism (PA) may cause myocardial injury."1.51Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism. ( Chen, X; Chen, Y; Li, Y; Shao, S; Wang, D; Wang, JG; Xu, JZ; Xu, TY; Zhang, W; Zhu, LM, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Yamada, T1
Fukuoka, H1
Hosokawa, Y1
Odake, Y1
Yoshida, K1
Matsumoto, R1
Bando, H1
Okada, Y1
Hirota, Y1
Iguchi, G1
Ogawa, W1
Takahashi, Y1
Wang, D1
Xu, JZ1
Chen, X1
Chen, Y1
Shao, S1
Zhang, W1
Zhu, LM1
Xu, TY1
Li, Y1
Wang, JG1
Boonen, L1
Verbrugge, FH1
Nijst, P1
Noyens, P1
De Vusser, P1
Verhaert, D1
Van Lierde, J1
Vrolix, M1
Dupont, M1
Mullens, W1
Kishino, M1
Yoshimoto, T1
Nakadate, M1
Katada, Y1
Kanda, E1
Nakaminato, S1
Saida, Y1
Ogawa, Y1
Tateishi, U1
Cao, CX1
Yang, XC1
Gao, YX1
Zhuang, M1
Wang, KP1
Sun, LJ1
Wang, XS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diuretic Efficiency in Patients With Stable Heart Failure: Ion Excretion Capacity of the Kidneys (DIPSTICK) Study[NCT02288819]50 participants (Actual)Interventional2014-09-30Terminated (stopped due to Slow recruitment and a lack of funding to complete further follow-up)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

All-cause Mortality

(NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

New York Heart Association (NYHA) Functional Class

"NYHA class is a semi-quantitative measurement of functional capacity on a scale from 1 to 4:~No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, dyspnea (shortness of breath).~Slight limitation of physical activity. Comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea (shortness of breath).~Marked limitation of physical activity. Comfortable at rest. Less than ordinary activity causes fatigue, palpitation, or dyspnea.~Unable to carry on any physical activity without discomfort. Symptoms of heart failure at rest. If any physical activity is undertaken, discomfort increases.~For the purpose of this outcome parameter, the patient is contacted by phone 30 days after baseline and NYHA functional class is assessed by a study investigator." (NCT02288819)
Timeframe: 30 days after baseline

Interventionunits on a scale from 1 to 4 (Mean)
Loop Diuretic Downtitration1.41

Number of Participants Rehospitalized for Heart Failure

Unplanned hospital admission for symptoms of congestion and/or low output heart failure requiring either intravenous therapy and/or increase of oral diuretics. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

Number of Participants Requiring a Dose Increase in Loop Diuretics

Dose increase of oral maintenance therapy with loop diuretics compared to the final dose achieved in the study 7 days after baseline. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

Number of Participants With Successful Downtitration of Loop Diuretics (no Weight Increase >1,5 kg)

After baseline evaluation, loop diuretics are temporarily downtitrated or stopped for 7 consecutive days. The patient is instructed to measure his/her weight in the morning of these days, immediately after waking up, on the same balance. In case of weight increase >1,5 kg, the original dose of diuretics is restored. To check this, patients are contacted by phone after 3 and 7 days. If the patient has not gained >1,5 kg of weight after 7 days, loop diuretics are considered to be successfully downtitrated. (NCT02288819)
Timeframe: 7 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration37

Self-reported Lower Leg Edema

The patient is contacted by phone 30 days after baseline and asked for self-reported presence of lower leg edema. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration1

Self-reported Orthopnea

The patient is contacted by phone 30 days after baseline and asked for self-reported orthopnea. (NCT02288819)
Timeframe: 30 days after baseline

InterventionParticipants (Count of Participants)
Loop Diuretic Downtitration5

Weight Change

Weight change [kg] 30 days after baseline compared to weight 7 days after baseline (after achieving the final dose of loop diuretics). (NCT02288819)
Timeframe: 30 days after baseline

Interventionkg (Mean)
Loop Diuretic Downtitration-0.261

Weight Change

Weight change [kg] 7 days after baseline compared to baseline weight. (NCT02288819)
Timeframe: 7 days after baseline

Interventionkg (Mean)
Loop Diuretic Downtitration0.502

Other Studies

5 other studies available for aldosterone and Asymptomatic Conditions

ArticleYear
Patients with pheochromocytoma exhibit low aldosterone renin ratio-preliminary reports.
    BMC endocrine disorders, 2020, Sep-11, Volume: 20, Issue:1

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Asymptomatic Diseases; Cross-Sectional Studies; C

2020
Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism.
    American journal of hypertension, 2019, 01-15, Volume: 32, Issue:2

    Topics: Adult; Aged; Aldosterone; Asymptomatic Diseases; Biomarkers; Blood Pressure; Case-Control Studies; C

2019
Subclinical volume overload in stable outpatients with chronic heart failure.
    Acta cardiologica, 2016, Volume: 71, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Asymptomatic Disease

2016
Optimization of left adrenal vein sampling in primary aldosteronism: Coping with asymmetrical cortisol secretion.
    Endocrine journal, 2017, Mar-31, Volume: 64, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Asymptomatic Diseases

2017
Expression of aldosterone synthase and adrenocorticotropic hormone receptor in adrenal incidentalomas from normotensive and hypertensive patients: Distinguishing subclinical or atypical primary aldosteronism from adrenal incidental
    International journal of molecular medicine, 2012, Volume: 30, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Asymptomatic Diseases; Biomark

2012