Page last updated: 2024-11-07

aldosterone and Aortic Valve Stenosis

aldosterone has been researched along with Aortic Valve Stenosis in 9 studies

Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.

Research Excerpts

ExcerptRelevanceReference
" We evaluated the effects of aldosterone antagonist spironolactone on cardiac remodeling in rats with ascending aortic stenosis (AS)."7.83Effects of early aldosterone antagonism on cardiac remodeling in rats with aortic stenosis-induced pressure overload. ( Campos, DHS; Cezar, MDM; Cicogna, AC; Costa, LCO; Damatto, RL; Iyomasa, RM; Martinez, PF; Minicucci, MF; Okoshi, K; Okoshi, MP; Silva, MB, 2016)
" This study determined whether myocardial aldosterone and angiotensin II release occurs in patients with aortic stenosis (AS) and/or coronary heart disease (CHD) with normal left ventricular ejection fractions and no clinical heart failure."7.73Coronary sinus and ascending aortic levels of aldosterone, angiotensin II, and B-type natriuretic peptide in patients with aortic stenosis and in patients with coronary heart disease. ( Richards, AM; Stewart, RA; Wasywich, CA; Webster, MW, 2006)
"Aldosterone (Aldo) promotes proteoglycan synthesis in valve interstitial cells (VICs) from mitral valves via the mineralocorticoid receptor (MR)."5.72Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis. ( Álvarez de la Rosa, D; Álvarez, V; Arrieta, V; Fernández-Celis, A; Gainza, A; Garaikoetxea, M; García-Peña, A; Jaisser, F; Jover, E; López-Andrés, N; Martín-Nuñez, E; Matilla, L; Navarro, A; Sádaba, R, 2022)
" We evaluated the effects of aldosterone antagonist spironolactone on cardiac remodeling in rats with ascending aortic stenosis (AS)."3.83Effects of early aldosterone antagonism on cardiac remodeling in rats with aortic stenosis-induced pressure overload. ( Campos, DHS; Cezar, MDM; Cicogna, AC; Costa, LCO; Damatto, RL; Iyomasa, RM; Martinez, PF; Minicucci, MF; Okoshi, K; Okoshi, MP; Silva, MB, 2016)
" This study determined whether myocardial aldosterone and angiotensin II release occurs in patients with aortic stenosis (AS) and/or coronary heart disease (CHD) with normal left ventricular ejection fractions and no clinical heart failure."3.73Coronary sinus and ascending aortic levels of aldosterone, angiotensin II, and B-type natriuretic peptide in patients with aortic stenosis and in patients with coronary heart disease. ( Richards, AM; Stewart, RA; Wasywich, CA; Webster, MW, 2006)
"Aldosterone (Aldo) promotes proteoglycan synthesis in valve interstitial cells (VICs) from mitral valves via the mineralocorticoid receptor (MR)."1.72Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis. ( Álvarez de la Rosa, D; Álvarez, V; Arrieta, V; Fernández-Celis, A; Gainza, A; Garaikoetxea, M; García-Peña, A; Jaisser, F; Jover, E; López-Andrés, N; Martín-Nuñez, E; Matilla, L; Navarro, A; Sádaba, R, 2022)
"Thirteen aortic stenosis and/or aortic regurgitation patients were matched with 13 control subjects."1.29Twenty-four-hour ambulatory blood pressure and vasoactive hormones in valvular aortic disease. ( Bagger, JP; Jensen, LW; Pedersen, EB, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Matilla, L1
Jover, E1
Garaikoetxea, M1
Martín-Nuñez, E1
Arrieta, V2
García-Peña, A2
Navarro, A1
Fernández-Celis, A2
Gainza, A2
Álvarez, V2
Álvarez de la Rosa, D1
Sádaba, R2
Jaisser, F2
López-Andrés, N2
Ibarrola, J1
Martinez-Martinez, E1
Cachofeiro, V1
Santamaria, E1
Fernandez-Irigoyen, J1
Okoshi, MP1
Cezar, MDM1
Iyomasa, RM1
Silva, MB1
Costa, LCO1
Martinez, PF1
Campos, DHS1
Damatto, RL1
Minicucci, MF1
Cicogna, AC1
Okoshi, K1
Wasywich, CA1
Webster, MW1
Richards, AM1
Stewart, RA1
Szafranek, A1
Jasinski, M1
Kolowca, M1
Gemel, M1
Wos, S1
Jensen, LW1
Bagger, JP1
Pedersen, EB1
Beckerhoff, R1
Lewin, RF1
Raff, H1
Findling, JW1
Skelton, MM1
Cowley, AW1
King, JF1
Dorros, G1
Renner, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055]Phase 475 participants (Anticipated)Interventional2023-08-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aldosterone and Aortic Valve Stenosis

ArticleYear
[The effect of an angiotensin antagonist on blood pressure, renin and aldosterone secretion and its pathogenetic importance].
    Schweizerische medizinische Wochenschrift. Supplementum, 1978, Issue:7

    Topics: Aldosterone; Angiotensin II; Aortic Valve Stenosis; Bartter Syndrome; Binding, Competitive; Blood Pr

1978

Other Studies

8 other studies available for aldosterone and Aortic Valve Stenosis

ArticleYear
Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:8

    Topics: Aldosterone; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Female; Fibrosis; Hum

2022
Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12.
    Scientific reports, 2018, 05-01, Volume: 8, Issue:1

    Topics: A Kinase Anchor Proteins; Aged; Aged, 80 and over; Aldosterone; Animals; Aortic Valve Stenosis; Case

2018
Effects of early aldosterone antagonism on cardiac remodeling in rats with aortic stenosis-induced pressure overload.
    International journal of cardiology, 2016, Nov-01, Volume: 222

    Topics: Aldosterone; Animals; Aortic Valve Stenosis; Cardiomegaly; Electrocardiography; Male; Mineralocortic

2016
Coronary sinus and ascending aortic levels of aldosterone, angiotensin II, and B-type natriuretic peptide in patients with aortic stenosis and in patients with coronary heart disease.
    The American journal of cardiology, 2006, Apr-01, Volume: 97, Issue:7

    Topics: Aged; Aldosterone; Angiotensin II; Aorta; Aortic Valve Stenosis; Coronary Disease; Female; Humans; M

2006
Plasma ANP and renin-angiotensin-aldosterone system as new parameters describing the hemodynamics of the circulatory system after implantation of stented or stentless aortic valves.
    The Journal of heart valve disease, 2006, Volume: 15, Issue:5

    Topics: Aged; Aldosterone; Angiotensins; Aortic Valve Stenosis; Atrial Natriuretic Factor; Biomarkers; Biopr

2006
Twenty-four-hour ambulatory blood pressure and vasoactive hormones in valvular aortic disease.
    Blood pressure, 1996, Volume: 5, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Aortic Valve Insufficiency; Aortic Valve Stenosis; Arginin

1996
Stimulation of atrial natriuretic peptide and vasopressin during percutaneous transluminal aortic valvuloplasty.
    American heart journal, 1989, Volume: 118, Issue:2

    Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Aortic Valve Stenosis; Arginine Vasopressin; Atrial

1989
[Diagnosis of arterial hypertension].
    Munchener medizinische Wochenschrift (1950), 1970, Oct-09, Volume: 112, Issue:41

    Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiography; Aortic Valve Stenosis; Arteries; Catecholamines

1970