aldosterone has been researched along with Angina, Unstable in 2 studies
Angina, Unstable: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To address this question, we examined data from the dal-OUTCOMES trial that compared the cholesteryl ester transfer protein inhibitor dalcetrapib with placebo, beginning 4 to 12 weeks after an index acute coronary syndrome." | 7.85 | Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. ( Ballantyne, CM; Barter, PJ; Gunzburger, E; Kallend, D; Kittelson, J; Leiter, LA; Leitersdorf, E; McMurray, JJ; Nicholls, SJ; Olsson, AG; Pitts, R; Schwartz, GG; Shah, PK; Tardif, JC, 2017) |
| "To address this question, we examined data from the dal-OUTCOMES trial that compared the cholesteryl ester transfer protein inhibitor dalcetrapib with placebo, beginning 4 to 12 weeks after an index acute coronary syndrome." | 3.85 | Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. ( Ballantyne, CM; Barter, PJ; Gunzburger, E; Kallend, D; Kittelson, J; Leiter, LA; Leitersdorf, E; McMurray, JJ; Nicholls, SJ; Olsson, AG; Pitts, R; Schwartz, GG; Shah, PK; Tardif, JC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pitts, R | 1 |
| Gunzburger, E | 1 |
| Ballantyne, CM | 1 |
| Barter, PJ | 1 |
| Kallend, D | 1 |
| Leiter, LA | 1 |
| Leitersdorf, E | 1 |
| Nicholls, SJ | 1 |
| Shah, PK | 1 |
| Tardif, JC | 1 |
| Olsson, AG | 1 |
| McMurray, JJ | 1 |
| Kittelson, J | 1 |
| Schwartz, GG | 1 |
| Mihailidou, AS | 1 |
| Loan Le, TY | 1 |
| Mardini, M | 1 |
| Funder, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blind, Placebo-controlled Study Assessing the Effect of RO4607381 on Cardiovascular Mortality and Morbidity in Clinically Stable Patients With a Recent Acute Coronary Syndrome[NCT00658515] | Phase 3 | 15,871 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00658515)
Timeframe: At 53 Months
| Intervention | mg/dL (Least Squares Mean) |
|---|---|
| Dalcetrapib (RO4607381) | 44.96 |
| Placebo | 15.60 |
(NCT00658515)
Timeframe: Throughout Study, up to 53 Months
| Intervention | Participants (Count of Participants) |
|---|---|
| Dalcetrapib (RO4607381) | 226 |
| Placebo | 229 |
Number of cardiovascular events per patient per year (NCT00658515)
Timeframe: From date of randomization to first event up to 48 months
| Intervention | Event per Patient Years of Followup (Number) |
|---|---|
| Dalcetrapib (RO4607381) | 0.034050 |
| Placebo | 0.032759 |
2 other studies available for aldosterone and Angina, Unstable
| Article | Year |
|---|---|
Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure.
Topics: Acute Coronary Syndrome; Aged; Aldosterone; Amides; Angina, Unstable; Anticholesteremic Agents; Card | 2017 |
Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction.
Topics: Aldosterone; Angina, Unstable; Animals; Apoptosis; Dexamethasone; Glucocorticoids; Hormone Antagonis | 2009 |