Page last updated: 2024-11-07

aldosterone and Alcohol Abuse

aldosterone has been researched along with Alcohol Abuse in 31 studies

Research Excerpts

ExcerptRelevanceReference
" A simple clinical method using the urinary Na/K ratio as a guide to spironolactone dosage is outlined."5.25Spironolactone diuresis in patients with cirrhosis and ascites. ( Eggert, RC, 1970)
"Chronic alcohol abuse causes severe and persistent alterations in the hormonal regulatory systems of electrolyte and water balance."1.32Persistent alterations of vasopressin and N-terminal proatrial natriuretic peptide plasma levels in long-term abstinent alcoholics. ( Döring, WK; Ehrenreich, H; Herzenstiel, MN; Jahn, H; Krampe, H; Poser, W; Pralle, L; Sieg, S; Wegerle, E, 2003)
"Aldosterone level was significantly increased on admission (319 ng/ml)."1.29Hormonal derangements in patients with severe alcohol intoxication. ( Bieglmayer, C; Derfler, K; Hirschl, MM; Laggner, AN; Röggla, H; Seidler, D; Zeiner, A, 1994)
"Blood pressure, alcohol withdrawal symptoms and plasma levels of cortisol, aldosterone and renin activity and serum dopamine beta-hydroxylase concentrations were measured in 65 alcoholics on the first and fourth days after admission for detoxification."1.27Blood pressure and pressor mechanisms during alcohol withdrawal. ( Bannan, LT; Beevers, DG; Ingram, MC; Potter, JF; Saunders, JB, 1983)
" A simple clinical method using the urinary Na/K ratio as a guide to spironolactone dosage is outlined."1.25Spironolactone diuresis in patients with cirrhosis and ascites. ( Eggert, RC, 1970)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199020 (64.52)18.7374
1990's6 (19.35)18.2507
2000's2 (6.45)29.6817
2010's2 (6.45)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Lékó, AH1
McGinn, MA1
Farokhnia, M2
Aoun, EG1
Jimenez, VA1
Vendruscolo, LF1
Walter, NAR1
Barbier, E1
Ferrulli, A2
Haass-Koffler, CL2
Darakjian, P1
Lee, MR1
Addolorato, G2
Heilig, M1
Hitzemann, R1
Koob, GF1
Grant, KA1
Leggio, L3
Long, VM1
Magill, M1
Kenna, GA2
Swift, RM2
Döring, WK1
Herzenstiel, MN1
Krampe, H1
Jahn, H1
Pralle, L1
Sieg, S1
Wegerle, E1
Poser, W1
Ehrenreich, H1
Cardone, S1
Miceli, A1
Gasbarrini, G1
Halberg, F1
Elias, AN1
Meshkinpour, H1
Valenta, LJ1
Grossman, MK1
Bannan, LT3
Potter, JF3
Beevers, DG3
Saunders, JB3
Walters, JR2
Ingram, MC2
Beevers, DB1
Paton, A1
Hirschl, MM1
Derfler, K1
Bieglmayer, C1
Röggla, H1
Zeiner, A1
Seidler, D1
Laggner, AN1
Veglio, F1
Rovera, L1
Molino, P1
Schiavone, D1
Chiandussi, L1
Farmer, RW3
Fabre, LF4
Kovács, GL1
Bezzegh, A1
Nyuli, L1
Akker, LV1
Abrikosova, SIu1
Piatnitskaia, IN1
Balabolkin, MI1
Laso, FJ1
González-Buitrago, JM1
Martin-Ruiz, C1
Vicens, E1
Moyano, JC1
Rachamin, G1
Luttge, WG1
Hunter, BE1
Walker, DW1
Borodulin, VG1
Zubovskiĭ, GA1
Avdienko, VN1
von Bardeleben, U1
Holsboer, F1
De Marchi, S2
Cecchin, E2
Regan, TJ1
Pathan, A1
Weisse, AB1
Eaddy, C1
Torres, R1
Roach, MK1
Fritchie, GE1
McIsaac, WM2
Shishov, VI1
Bel, A1
Rousset, H1
Fournier, G1
Ueda, Y1
Ogura, Y1
Hanaoka, H1
Ishida, M1
Okamoto, T1
Harris, RT1
Howard, PY1
Eggert, RC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Spironolactone in Alcohol Use Disorder (SAUD): A Double-Blind, Placebo-Controlled, Ascending Dose, Phase 1b Study[NCT05807139]Phase 120 participants (Anticipated)Interventional2024-01-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for aldosterone and Alcohol Abuse

ArticleYear
Quo vadis basic and clinical chronobiology: promise for health maintenance.
    The American journal of anatomy, 1983, Volume: 168, Issue:4

    Topics: Adrenal Cortex; Alcoholism; Aldosterone; Biological Clocks; Blood Pressure; Breast Neoplasms; Cardio

1983
Some endocrine aspects of alcoholism.
    Advances in experimental medicine and biology, 1975, Volume: 56

    Topics: 20-alpha-Dihydroprogesterone; Adrenal Cortex; Adult; Alcoholism; Alcohols; Aldosterone; Animals; Cir

1975
Human corticotropin releasing hormone: clinical studies in patients with affective disorders, alcoholism, panic disorder and in normal controls.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12 Suppl

    Topics: Adrenocorticotropic Hormone; Alcoholism; Aldosterone; Corticotropin-Releasing Hormone; Depression; D

1988
[Magnesium and the kidney].
    Saishin igaku. Modern medicine, 1968, Dec-10, Volume: 23, Issue:12

    Topics: Alcoholism; Aldosterone; Animals; Diuretics; Dogs; Humans; Kidney; Kidney Failure, Chronic; Magnesiu

1968

Trials

1 trial available for aldosterone and Alcohol Abuse

ArticleYear
Renin and aldosterone but not the natriuretic peptide correlate with obsessive craving in medium-term abstinent alcohol-dependent patients: a longitudinal study.
    Alcohol (Fayetteville, N.Y.), 2008, Volume: 42, Issue:5

    Topics: Alcoholism; Aldosterone; Baclofen; Behavior, Addictive; Counseling; Female; Humans; Longitudinal Stu

2008

Other Studies

26 other studies available for aldosterone and Alcohol Abuse

ArticleYear
The Mineralocorticoid Receptor: An Emerging Pharmacotherapeutic Target for Alcohol Use Disorder?
    ACS chemical neuroscience, 2022, 07-06, Volume: 13, Issue:13

    Topics: Alcohol Drinking; Alcoholism; Aldosterone; Humans; Mineralocorticoid Receptor Antagonists; Receptors

2022
A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans.
    Molecular psychiatry, 2018, Volume: 23, Issue:6

    Topics: Adult; Alcohol Drinking; Alcoholism; Aldosterone; Amygdala; Animals; Cytochrome P-450 CYP11B2; Disea

2018
Intravenous administration of ghrelin increases serum cortisol and aldosterone concentrations in heavy-drinking alcohol-dependent individuals: Results from a double-blind, placebo-controlled human laboratory study.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: Administration, Intravenous; Alcoholism; Aldosterone; Craving; Cues; Double-Blind Method; Ghrelin; H

2019
Persistent alterations of vasopressin and N-terminal proatrial natriuretic peptide plasma levels in long-term abstinent alcoholics.
    Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:5

    Topics: Adult; Alanine Transaminase; Alcoholism; Aldosterone; Angiotensin II; Aspartate Aminotransferases; A

2003
Pseudo-Cushing's syndrome: the role of alcohol.
    Journal of clinical gastroenterology, 1982, Volume: 4, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Aldosterone; Cushing Syndrome; Diagnosis, Differenti

1982
Effect of alcohol withdrawal on blood pressure, plasma renin activity, aldosterone, cortisol and dopamine beta-hydroxylase.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:6

    Topics: Adult; Aged; Alcoholism; Aldosterone; Blood Pressure; Dopamine beta-Hydroxylase; Ethanol; Female; Hu

1984
Blood pressure and pressor mechanisms during alcohol withdrawal.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:2

    Topics: Alcoholism; Aldosterone; Blood Pressure; Dopamine beta-Hydroxylase; Humans; Hydrocortisone; Metaneph

1983
Alcohol and hypertension.
    Contributions to nephrology, 1982, Volume: 30

    Topics: Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Aldosterone; Blood Pressure; Dopam

1982
Hormonal derangements in patients with severe alcohol intoxication.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Alcoholic Intoxication; Alcoholism; Aldosterone; Ethanol; Female; Humans; Kidney

1994
Bioelectric impedance analysis of body composition in alcohol-related essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Alcoholism; Aldosterone; Body Composition; Body Water; Electric Impedance; Extracellular Spac

1993
Disturbances of volume regulation in chronic alcoholics: a correlation with the excitability of the central nervous system.
    Progress in brain research, 1992, Volume: 91

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Aldosterone; Atrial Natriuretic Factor; Central Nerv

1992
[Hormonal changes and biologically active substances in alcoholic women in the reproductive age].
    Akusherstvo i ginekologiia, 1991, Issue:10

    Topics: Acetylcholine; Adolescent; Adult; Age Factors; Alcoholism; Aldosterone; Female; Gonadal Steroid Horm

1991
[The hypophyseal-adrenal system in chronic alcoholism].
    Sovetskaia meditsina, 1990, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Alcoholism; Aldosterone; Humans; Hydrocortisone;

1990
Inter-relationship between serum potassium and plasma catecholamines and 3':5' cyclic monophosphate in alcohol withdrawal.
    Drug and alcohol dependence, 1990, Volume: 26, Issue:2

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Aldosterone; Cyclic AMP; Epinephrine; Humans; Hypokalemia;

1990
Neither chronic exposure to ethanol nor aging affects type I or type II corticosteroid receptors in rat hippocampus.
    Experimental neurology, 1989, Volume: 106, Issue:2

    Topics: Adrenal Cortex Hormones; Aging; Alcoholism; Aldosterone; Animals; Corticosterone; Dexamethasone; Hip

1989
[Functional state of the hypophyseo-adrenal system in patients with chronic alcoholism and various degrees of liver damage].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988, Volume: 88, Issue:9

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Aldosterone; Humans; Hydrocortisone; Liver Diseases,

1988
Relation between plasma aldosterone concentration and renal handling of sodium and potassium in alcoholics during the withdrawal phase.
    Nephron, 1986, Volume: 42, Issue:2

    Topics: Alcoholism; Aldosterone; Humans; Kidney; Potassium; Renin; Sodium; Substance Withdrawal Syndrome

1986
Two possible mechanisms for alcohol associated hypertension.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1985, Volume: 176

    Topics: Adult; Alcohol Drinking; Alcoholism; Aldosterone; Blood Pressure; Double-Blind Method; Ethanol; Huma

1985
Alcohol withdrawal and hypertension: evidence for a kidney abnormality.
    Clinical science (London, England : 1979), 1985, Volume: 69, Issue:2

    Topics: Alcoholism; Aldosterone; Humans; Hydrocortisone; Hypertension; Kidney; Natriuresis; Renin; Substance

1985
The contribution of arterial pressure to the cardiac dysfunction of chronic alcoholism.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 703

    Topics: Adult; Alcoholism; Aldosterone; Blood Pressure; Catecholamines; Echocardiography; Electrolytes; Hear

1985
Biochemical and metabolic aspects of alcoholism.
    Annals of the New York Academy of Sciences, 1973, Apr-30, Volume: 215

    Topics: Adrenal Glands; Age Factors; Alcoholism; Aldosterone; Amino Acids; Androgens; Animals; Blood Glucose

1973
[The state of adrenal cortical function in chronic alcoholism].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: 11-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Alcoholism; Aldostero

1973
[Quadriplegia, severe hypokalemic alkalosis, tetany, arterial hypertension in relation to excessive licorice extract consumption in a chronic alcoholic].
    Lyon medical, 1972, Sep-10, Volume: 228, Issue:13

    Topics: Alcoholism; Aldosterone; Alkalosis; Chronic Disease; Diabetes Complications; Electrocardiography; Gl

1972
Research training in alcoholism.
    Annals of the New York Academy of Sciences, 1971, Mar-29, Volume: 178

    Topics: Alcoholism; Aldosterone; Animals; Behavior; Blood Glucose; Carbon Isotopes; Central Nervous System;

1971
Endocrine abnormalities in male alcoholic subjects.
    Texas medicine, 1972, Volume: 68, Issue:10

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Alcoholism; Aldosterone; Androgens; Glucose Toler

1972
Spironolactone diuresis in patients with cirrhosis and ascites.
    British medical journal, 1970, Nov-14, Volume: 4, Issue:5732

    Topics: Alcoholism; Aldosterone; Ascites; Humans; Liver Cirrhosis; Potassium; Sodium; Spironolactone

1970