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aldosterone and Adrenal Cortex Cancer

aldosterone has been researched along with Adrenal Cortex Cancer in 601 studies

Research Excerpts

ExcerptRelevanceReference
"The objective of the study was to compare the sensitivity and specificity of (11)C-metomidate PET-computed tomography (CT) against the current gold standard of AVS."9.16Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas. ( Aigbirhio, F; Azizan, EA; Balan, K; Bird, N; Brown, MJ; Burton, TJ; Gurnell, M; Koo, B; Mackenzie, IS; Soloviev, DV, 2012)
"Imaging with [¹²³I]iodometomidate ([¹²³I]IMTO) has been shown to diagnose adrenocortical lesions with high sensitivity and specificity."7.79[¹²³I]Iodometomidate imaging in adrenocortical carcinoma. ( Allolio, B; Bock, S; Buck, AK; Fassnacht, M; Haenscheid, H; Hahner, S; Knoedler, P; Kreissl, MC; Reiners, C; Saeger, W; Schirbel, A; Verburg, FA, 2013)
" The purpose of the present study was to determine the effect of endothelin-1 (ET-1) and angiotensin II (Ang II), two potent vasoconstrictors that are also involved in heart failure, on aldosterone secretion by human adrenocortical carcinoma NCIH295R cells grown in 96-well plates."7.72Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II. ( Hu, CW; Jeng, AY; Webb, RL, 2004)
"The relation between serum cortisol, plasma renin activity, angiotensin II (Ang II), or aldosterone levels and peripheral blood cell (mononuclear leukocytes and platelets) angiotensin II type 1A (AT1A) and 1B (AT1B) receptor mRNA levels was examined in both patients with Cushing's syndrome (seven patients with Cushing's syndrome due to unilateral adrenal cortical adenoma) and control subjects (seven normotensive patients with renal cell carcinoma)."7.69Gene expression of angiotensin II receptor in blood cells of Cushing's syndrome. ( Maruyama, T; Saruta, T; Shibata, H; Suzuki, H, 1995)
" Nineteen out of 47 patients (40%) with confirmed unilateral aldosterone-producing adenoma (APA) were responsive to low-dose angiotensin II infusion (AII-R), as defined by an increase in plasma aldosterone concentration of > 50% over basal at 2 ng/kg per min for 60 min."7.68Angiotensin-responsive aldosterone-producing adenomas: postoperative disappearance of aldosterone response to angiotensin. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ, 1993)
" In vitro short-term production of cortisol by dispersed tumour and non-tumourous adrenal cortical cells was measured with and without added angiotensin II (AII) or adrenocorticotrophin (ACTH) in adrenals removed from five patients with primary aldosteronism."7.68Cortisol production by aldosterone-producing adenomas in vitro. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ, 1993)
"Urinary excretion of 18-hydroxycortisol (18-OHF), 18-hydroxycorticosterone (18-OHB) and aldosterone 18-glucuronide (Aldo-18-glu) was measured in 10 patients with primary aldosteronism; 5 with aldosterone-producing adenoma (APA) and 5 with idiopathic hyperaldosteronism (IHA), 10 patients with essential hypertension (EHT) and 11 normotensive subjects."7.68Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism. ( Iki, K; Itoh, Y; Miyamori, I; Takasaki, H; Takeda, R; Takeda, Y, 1992)
"The plasma aldosterone (A) and desoxycorticosterone (DOCS) levels were measured in 10 patients with primary aldosteronism and in 2 subgroups with low-renin hypertensive disease (LRHD): (1) those with normal adrenal glands++ (n - 11) and (2) those with structural changes in the cortex (n - 11)."7.68[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension]. ( Bulkina, OS; Gorbacheva, ON; Levitskaia, IuV; Obtrakht, NV; Sokolova, RI; Ustinova, SE, 1990)
" The present study evaluated plasma beta-endorphin, ACTH, cortisol, and aldosterone levels in patients with IHA (n = 10), aldosterone-producing adenomas (n = 4), essential hypertension (n = 11), and normal subjects (n = 10)."7.67Plasma beta-endorphin levels in primary aldosteronism. ( Berelowitz, B; Griffing, GT; Hudson, M; Manson, JA; McIntosh, T; Melby, JC; Salzman, R, 1985)
"An adrenal cortex adenoma, surgically removed from a female patient with primary aldosteronism, was used to examine the effect of ACTH, angiotensin II, gamma 3-MSH, and the N-terminal fragment of pro-opiomelanocortin purified from porcine anterior pituitaries on aldosterone release in vitro."7.66Effect of N-terminal portion of pro-opiomelanocortin on aldosterone release by human adrenal adenoma in vitro. ( Chrétien, M; Genest, J; Gutkowska, J; Hamet, P; Larivière, N; Lis, M; Maurice, G; Seidah, NG, 1981)
"In 31 patients with primary aldosteronism routine clinical and laboratory data, the effect of orthostasis on plasma aldosterone (PA), plasma renin activity (PRA) and cortisol (PC), effect of fludrocortisone or high sodium intake on basal PA and night-day fluctuations of basal PA and PC with and without suppression of pituitary ACTH by dexamethasone were determined to differentiate patients with a unilateral aldosterone producing tumour (adenoma, APA, n=20; carcinoma, CA, n=1) from those with idiopathic bilateral adrenal hyperplasia (IAH, n=10)."7.66Primary aldosteronism: inability to differentiate unilateral from bilateral adrenal lesions by various routine clinical and laboratory data and by peripheral plasma aldosterone. ( Furrer, J; Glänzer, K; Siebenschein, R; Siegenthaler, W; Studer, A; Vetter, H; Vetter, W; Witassek, F, 1978)
"Primary aldosteronism (PA) is the leading cause of secondary hypertension, accounting for over 10% of patients with high blood pressure."6.82Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas. ( Faucz, FR; Hannah-Shmouni, F; Pitsava, G; Stratakis, CA, 2022)
"Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension."6.72Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension. ( Azizan, EA; Pauzi, FA, 2021)
"Primary aldosteronism is the most common form of secondary hypertension."6.58Overview of aldosterone-related genetic syndromes and recent advances. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2018)
"Primary aldosteronism (PA) is caused by excessive production of aldosterone by the adrenal cortex and is determined by a benign aldosterone-producing adenoma (APA) in a significant proportion of cases."6.53Local Control of Aldosterone Production and Primary Aldosteronism. ( Barhanin, J; Lalli, E; Warth, R; Zennaro, MC, 2016)
"Primary aldosteronism is frequently caused by an adrenocortical aldosterone-producing adenoma (APA) carrying a somatic mutation that drives aldosterone overproduction."5.91Primary Aldosteronism: Spatial Multiomics Mapping of Genotype-Dependent Heterogeneity and Tumor Expansion of Aldosterone-Producing Adenomas. ( Blum, H; Gong, S; Koupourtidou, C; Krebs, S; Masserdotti, G; Meyer, LS; Rainey, WE; Reincke, M; Sun, N; Tetti, M; Walch, A; Williams, TA, 2023)
"His aldosterone/renin ratio was high and plasma renin activity was low."5.91[A Case of Aldosterone-Producing Adrenocortical Carcinoma]. ( Asai, S; Hashimoto, K; Ishihara, M; Kanamaru, S; Katsushima, H; Nakayasu, R; Oshiro, H; Shimizu, Y; Son, C; Tsuji, K; Utsunomiya, N, 2023)
"Primary aldosteronism (PA) is the most common form of endocrine hypertension and is characterized by inappropriately elevated aldosterone production via a renin-independent mechanism."5.91Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism. ( Bandulik, S; Blinder, AR; Else, T; Giordano, TJ; Kosmann, C; Kumar-Sinha, C; Lerario, AM; Nanba, K; Plain, A; Rainey, WE; Rege, J; Reincke, M; Sasano, H; Satoh, F; Turcu, AF; Udager, AM; Vats, P; Warth, R; Williams, TA; Yamazaki, Y, 2023)
"Primary aldosteronism (PA) is the most common type of secondary hypertension, and it is associated with a higher rate of cardiovascular complications."5.72KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma. ( Chang, CC; Chang, YY; Chen, ZW; Chiu, YW; Chou, CH; Huang, JZ; Hung, CS; Kang, VJ; Lee, BC; Liao, CW; Lin, YH; Lin, YL; Pan, CT; Tsai, CH; Wu, VC, 2022)
"In primary aldosteronism (PA), aldosterone secretion is relatively independent of the renin-angiotensin system, but can be regulated by several other stimuli."5.62Aldosterone is Aberrantly Regulated by Various Stimuli in a High Proportion of Patients with Primary Aldosteronism. ( Bourdeau, I; Lacroix, A; Martin, M; St-Jean, M, 2021)
"Accurate subtyping of the primary aldosteronism into aldosterone-producing adenoma (APA) and idiopathic adrenal hyperplasia (IAH) is important to direct for specific treatment modalities."5.56A clinical prediction score using age at diagnosis and saline infusion test parameters can predict aldosterone-producing adenoma from idiopathic adrenal hyperplasia. ( Chan, KW; Fong, CHY; Lau, EYF; Leung, HT; Leung, JYY; Tan, KCB; Woo, YC, 2020)
"In addition, primary aldosteronism (PA) is clinically associated with not only more frequent cardiovascular events but also secondary metabolic disorders including abnormal calcium metabolism, osteoporosis and others."5.51The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant "neoplastic" steroidogenesis in adrenals. ( Gao, X; Morimoto, R; Nakamura, Y; Ogata, H; Omata, K; Onodera, Y; Sasano, H; Satoh, F; Tezuka, Y; Yamazaki, Y, 2019)
"In patients with KCNJ5-mutated APA, left ventricular hypertrophy was significantly decreased by surgical treatment in patients from either Cured or Improved groups, although those patients with wild-type KCNJ5 showed no change."5.48KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma. ( Kitamoto, T; Nishikawa, T; Omura, M; Saito, J; Suematsu, S, 2018)
"The tumor was a benign adrenocortical adenoma composed predominantly of clear cells positive for 17α-hydroxylase, [hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerases], and aldosterone synthase."5.43Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism. ( Aizawa, T; Komatsu, M; Matsushita, T; Nakasone, Y; Nishikawa, T; Oguchi, K; Okubo, Y; Sasano, H; Sato, Y; Shirotori, K; Yamauchi, K; Yamazaki, Y, 2016)
"Aldosterone-producing adrenocortical carcinoma is a rare malignancy, which is usually diagnosed by histopathological examination of the excised tumor."5.43Aldosterone-producing adrenocortical carcinoma with prominent hepatic metastasis diagnosed by liver biopsy: a case report. ( Ebisawa, T; Hayashi, T; Iuchi, H; Ohashi, K; Sakamoto, M; Sasano, H; Suzuki, H; Tojo, K; Utsunomiya, K, 2016)
"Primary aldosteronism was confirmed by using the oral sodium-loading test."5.43Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation-Long-term Results and Recurrence Rate. ( Chiu, PW; Chow, FC; Chu, CC; Kong, AP; Liu, SY; Ng, EK; Tsui, TK; Wong, SK, 2016)
"Hyperkalemia was defined as serum potassium >5."5.42Clinical risk factors of postoperative hyperkalemia after adrenalectomy in patients with aldosterone-producing adenoma. ( Choi, SH; Hong, AR; Kim, JH; Kim, SW; Kim, SY; Ku, EJ; Moon, MK; Park, KS; Shin, CS, 2015)
"The molecular mechanisms of primary aldosteronism, a common cause of human hypertension, are unknown, but alterations of K(+) channels can play a key role."5.40Lower expression of the TWIK-related acid-sensitive K+ channel 2 (TASK-2) gene is a hallmark of aldosterone-producing adenoma causing human primary aldosteronism. ( Bader, M; Belloni, AS; Campos, AG; Caroccia, B; Fassina, A; Ferraro, S; Kuppusamy, M; Lenzini, L; Rainey, WE; Rossi, GP; Seccia, TM; Skander, G, 2014)
"Hyperkalemia is a potentially serious complication following adrenalectomy of aldosterone-producing adenomas (APA)."5.39Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma. ( Cheng, CJ; Chiang, WF; Lin, MY; Lin, SH; Sun, GH; Sung, CC; Wu, ST, 2013)
"Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases."5.38Aldosterone-producing adrenocortical carcinoma without hypertension. ( Bae, SB; Kim, SJ; Kim, YJ; Seo, SW; Song, MS, 2012)
"Normokalaemia does not exclude primary aldosteronism as the underlying cause of hypertension."5.35[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009]. ( Guthoff, M; Horger, M; Kirchhoff, K; Kurth, R; Müssig, K; Schnauder, G, 2009)
"Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia."5.35An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. ( Ahmetoğlu, A; Bahat, E; Imamoğlu, M; Karagüzel, G; Okten, A; Yildiz, K, 2009)
"Primary aldosteronism (PA) is a common curable disease of secondary hypertension."5.35Bilateral aldosterone-producing adenomas: differentiation from bilateral adrenal hyperplasia. ( Chang, HW; Chueh, SC; Hsieh, BS; Li, HY; Lin, WC; Lin, YH; Liu, KL; Wu, KD; Wu, VC, 2008)
"We report a rare case of adrenocortical carcinoma."5.32Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. ( Azizlerli, H; Kapran, Y; Kurtulmus, N; Yarman, S, 2004)
"The hypertension of Conn's syndrome is due to autonomous aldosterone production by a unilateral adrenocortical adenoma."5.31Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome). ( Connell, JM; Davies, E; Fraser, R; Friel, EC; Inglis, GC; Plouin, PF, 2001)
"Although primary aldosteronism is rare, especially during pregnancy, it should be always considered as one of etiologies of hypertension in pregnancy."5.30Primary aldosteronism with aldosterone-producing adrenal adenoma in a pregnant woman. ( Fujiyama, S; Inada, M; Iwasaka, T; Maruyama, K; Masaki, H; Matsubara, H; Matsuda, T; Mori, Y; Nagata, T; Okada, S; Umeda, Y; Yonemoto, T, 1999)
"We report a case of primary hyperaldosteronism due to unilateral diffuse hyperplasia."5.29Unilateral diffuse adrenal hyperplasia masquerading as aldosterone-producing adenoma in primary hyperaldosteronism. ( Hashimoto, T; Ishigooka, M; Kato, T; Kubota, Y; Nakada, T; Sasagawa, I; Suzuki, H, 1993)
"Aldosterone was secreted from the adrenal cortex in all patients and was increased by ACTH in 75% of the tissue specimens."5.28Basal and ACTH-stimulated cortisol and aldosterone release from adrenocortical adenomas in vitro. ( Grimelius, L; Gröndal, S; Hamberger, B; Thorén, M, 1991)
"A 7-year-old girl had hyperaldosteronism due to an adrenal cortical adenoma, a rare, surgically remediable cause of hypertension."5.27Hypertension caused by an aldosterone-secreting adenoma. Occurrence in a 7-year-old child. ( Bryer-Ash, M; Luetscher, JA; Rosenfeld, RG; Shochat, SJ; Tune, BM; Wilson, DM, 1984)
"A 50-year old female with primary aldosteronism and masked hyperaldosteronemia is reported."5.27A case report of aldosterone producing adenoma with masked hyperaldosteronemia. ( Arimori, S; Hiramatsu, K; Takahashi, K, 1986)
"Primary aldosteronism, when caused by an aldosterone-producing adenoma, is a surgically treatable condition."5.26An aldosterone-producing adrenal cortical adenoma. ( Hugo, JM; Shipton, EA, 1982)
"Aldosterone excretion was high, normal, or low in each of the three types of Cushing's syndrome."5.26Deoxycorticosterone and aldosterone excretion in Cushing's syndrome. ( Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K, 1980)
"These data show that patients with hyperaldosteronism from an adrenal adenoma or hyperplasia have a consistent and exaggerated response to ACTH."5.26Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kem, DC; Kramer, NJ; Weinberger, MH, 1978)
"Twenty patients suffering from primary hyperaldosteronism were studied."5.26[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977)
"The objective of the study was to compare the sensitivity and specificity of (11)C-metomidate PET-computed tomography (CT) against the current gold standard of AVS."5.16Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas. ( Aigbirhio, F; Azizan, EA; Balan, K; Bird, N; Brown, MJ; Burton, TJ; Gurnell, M; Koo, B; Mackenzie, IS; Soloviev, DV, 2012)
"Imaging with [¹²³I]iodometomidate ([¹²³I]IMTO) has been shown to diagnose adrenocortical lesions with high sensitivity and specificity."3.79[¹²³I]Iodometomidate imaging in adrenocortical carcinoma. ( Allolio, B; Bock, S; Buck, AK; Fassnacht, M; Haenscheid, H; Hahner, S; Knoedler, P; Kreissl, MC; Reiners, C; Saeger, W; Schirbel, A; Verburg, FA, 2013)
" The purpose of the present study was to determine the effect of endothelin-1 (ET-1) and angiotensin II (Ang II), two potent vasoconstrictors that are also involved in heart failure, on aldosterone secretion by human adrenocortical carcinoma NCIH295R cells grown in 96-well plates."3.72Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II. ( Hu, CW; Jeng, AY; Webb, RL, 2004)
"The relation between serum cortisol, plasma renin activity, angiotensin II (Ang II), or aldosterone levels and peripheral blood cell (mononuclear leukocytes and platelets) angiotensin II type 1A (AT1A) and 1B (AT1B) receptor mRNA levels was examined in both patients with Cushing's syndrome (seven patients with Cushing's syndrome due to unilateral adrenal cortical adenoma) and control subjects (seven normotensive patients with renal cell carcinoma)."3.69Gene expression of angiotensin II receptor in blood cells of Cushing's syndrome. ( Maruyama, T; Saruta, T; Shibata, H; Suzuki, H, 1995)
"To investigate the clinical significance of plasma dehydroepiandrosterone sulfate (DHEAS) measurements, 175 patients with histologically confirmed adrenal tumors, 10 cortisol-producing adenomas, 59 aldosterone-producing adenomas, 56 non-hyperfunctioning adenomas, 13 adrenocortical carcinomas, 13 adrenal cysts, and 24 adrenomedullary tumors were studied."3.69Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery. ( Adleff, V; Fútó, L; Gláz, E; Jakab, C; Kiss, R; Rácz, K; Tóth, M; Varga, I, 1997)
" Nineteen out of 47 patients (40%) with confirmed unilateral aldosterone-producing adenoma (APA) were responsive to low-dose angiotensin II infusion (AII-R), as defined by an increase in plasma aldosterone concentration of > 50% over basal at 2 ng/kg per min for 60 min."3.68Angiotensin-responsive aldosterone-producing adenomas: postoperative disappearance of aldosterone response to angiotensin. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ, 1993)
" In vitro short-term production of cortisol by dispersed tumour and non-tumourous adrenal cortical cells was measured with and without added angiotensin II (AII) or adrenocorticotrophin (ACTH) in adrenals removed from five patients with primary aldosteronism."3.68Cortisol production by aldosterone-producing adenomas in vitro. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ, 1993)
"In order to elucidate the steroidogenesis of clinically nonfunctioning adrenocortical adenoma, we studied the aldosterone, cortisol (F) and dehydroepiandrosterone (DHEA) content and the expression of mRNA of cytochrome P450 for side chain cleavage (P450scc), 17 alpha-hydroxylase (P450c17)."3.68Disordered expression of adrenal steroidogenic P450 mRNAs in incidentally discovered nonfunctioning adrenal adenoma. ( Haji, M; Nawata, H; Ogo, A; Ohashi, M; Takayanagi, R; Yanase, T, 1992)
"Urinary excretion of 18-hydroxycortisol (18-OHF), 18-hydroxycorticosterone (18-OHB) and aldosterone 18-glucuronide (Aldo-18-glu) was measured in 10 patients with primary aldosteronism; 5 with aldosterone-producing adenoma (APA) and 5 with idiopathic hyperaldosteronism (IHA), 10 patients with essential hypertension (EHT) and 11 normotensive subjects."3.68Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism. ( Iki, K; Itoh, Y; Miyamori, I; Takasaki, H; Takeda, R; Takeda, Y, 1992)
"The plasma aldosterone (A) and desoxycorticosterone (DOCS) levels were measured in 10 patients with primary aldosteronism and in 2 subgroups with low-renin hypertensive disease (LRHD): (1) those with normal adrenal glands++ (n - 11) and (2) those with structural changes in the cortex (n - 11)."3.68[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension]. ( Bulkina, OS; Gorbacheva, ON; Levitskaia, IuV; Obtrakht, NV; Sokolova, RI; Ustinova, SE, 1990)
"Low-dose angiotensin II (ANG II) infusion raised plasma atrial natriuretic peptide (ANP) levels only when endogenous renin-angiotensin levels were low, as in aldosterone-producing adenoma."3.67Atrial natriuretic peptide levels during angiotensin infusion and indomethacin administration are consistent with angiotensin-mediated regulation in man. ( Gordon, RD; Klemm, SA; Tunny, TJ, 1987)
" The present study evaluated plasma beta-endorphin, ACTH, cortisol, and aldosterone levels in patients with IHA (n = 10), aldosterone-producing adenomas (n = 4), essential hypertension (n = 11), and normal subjects (n = 10)."3.67Plasma beta-endorphin levels in primary aldosteronism. ( Berelowitz, B; Griffing, GT; Hudson, M; Manson, JA; McIntosh, T; Melby, JC; Salzman, R, 1985)
"Cells isolated from five aldosterone-producing adenomas were used to study glucocorticoid and aldosterone production in response to ACTH, angiotensin II (A II), and peptides derived from proopiomelanocortin (POMC), viz."3.67Effects of proopiomelanocortin peptides and angiotensin II on steroidogenesis in isolated aldosteronoma cells. ( Bogyo, A; de Smitter, N; Girard, F; Pham-Huu-Trung, MT, 1985)
"To determine the potential therapeutic effect of calcium entry blockade in primary aldosteronism, 10 patients (5 adenoma and 5 hyperplasia) documented by endocrine testing and/or surgery were given nifedipine (20 mg, sublingually) in the afternoon."3.67Therapeutic effect of calcium channel blockade in primary aldosteronism. ( Horton, R; Hsueh, W; Nadler, JL, 1985)
"An adrenal cortex adenoma, surgically removed from a female patient with primary aldosteronism, was used to examine the effect of ACTH, angiotensin II, gamma 3-MSH, and the N-terminal fragment of pro-opiomelanocortin purified from porcine anterior pituitaries on aldosterone release in vitro."3.66Effect of N-terminal portion of pro-opiomelanocortin on aldosterone release by human adrenal adenoma in vitro. ( Chrétien, M; Genest, J; Gutkowska, J; Hamet, P; Larivière, N; Lis, M; Maurice, G; Seidah, NG, 1981)
"Isolated adrenocortical cells from 6 patients with a 'normal' zona fasciculata, 4 patients with a 'normal' zona glomerulosa, and tumour cells from 1 adrenocortical adenoma and 1 carcinoma were incubated with and without increasing concentrations of ACTH 1-24 (10(-13) M to 10(-9) M) or Asp1-Ile5-angiotensin II (10(-11) M to 10(-7) M)."3.66Effects of angiotensin II and ACTH on normal and tumourous human adrenocortical cells. ( Belkien, L; Belmega, W; Fiedler, U; Häring, R; Oelkers, W; Shirpai, M, 1983)
" Materials in the organic extract from a pH-1 hydrolysate of pooled pregnancy urine, were located by their ability to bind with aldosterone and tetrahydroaldosterone antisera and exhibited similar chromatographic properties to the radioactive metabolites."3.66Characterisation of aldosterone metabolites cross reacting with aldosterone and tetrahydroaldosterone antibodies. ( Biglieri, EG; Haack, D; Honour, JW; Lichtwald, K; Vecsei, P, 1982)
"In 31 patients with primary aldosteronism routine clinical and laboratory data, the effect of orthostasis on plasma aldosterone (PA), plasma renin activity (PRA) and cortisol (PC), effect of fludrocortisone or high sodium intake on basal PA and night-day fluctuations of basal PA and PC with and without suppression of pituitary ACTH by dexamethasone were determined to differentiate patients with a unilateral aldosterone producing tumour (adenoma, APA, n=20; carcinoma, CA, n=1) from those with idiopathic bilateral adrenal hyperplasia (IAH, n=10)."3.66Primary aldosteronism: inability to differentiate unilateral from bilateral adrenal lesions by various routine clinical and laboratory data and by peripheral plasma aldosterone. ( Furrer, J; Glänzer, K; Siebenschein, R; Siegenthaler, W; Studer, A; Vetter, H; Vetter, W; Witassek, F, 1978)
"Primary aldosteronism (PA) is the leading cause of secondary hypertension, accounting for over 10% of patients with high blood pressure."2.82Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas. ( Faucz, FR; Hannah-Shmouni, F; Pitsava, G; Stratakis, CA, 2022)
"Primary aldosteronism affects up to 10% of hypertensive patients and is responsible for treatment resistance and increased cardiovascular risk."2.82Identification of risk loci for primary aldosteronism in genome-wide association studies. ( Abdellatif, AB; Amar, L; Baron, S; Beuschlein, F; Boulkroun, S; Chantalat, S; Cosentino, T; Cusi, D; De Sousa, K; Deleuze, JF; Deschasaux, M; Druesne-Pecollo, N; Empana, JP; Ferey, M; Fernandes-Rosa, FL; Frouin, A; Gieger, C; Giscos-Douriez, I; Jeunemaitre, X; Jouven, X; Larsen, CK; Le Floch, E; Lenzini, L; Meatchi, T; Meneton, P; Peters, A; Reincke, M; Rossi, GP; Saintpierre, B; Salvi, E; Touvier, M; Waldenberger, M; Zennaro, MC, 2022)
"Primary aldosteronism is the most common form of secondary arterial hypertension, due to excessive aldosterone production from the adrenal gland."2.82Vascular and hormonal interactions in the adrenal gland. ( Abdellatif, AB; Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2022)
"Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension."2.72Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension. ( Azizan, EA; Pauzi, FA, 2021)
"Primary aldosteronism (PA) is the most common form of secondary hypertension affecting 5%-10% of patients with arterial hypertension."2.66Old and new genes in primary aldosteronism. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2020)
"Primary aldosteronism (PA) is the most common form of endocrine hypertension."2.66Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism. ( Gong, S; Meyer, LS; Reincke, M; Williams, TA, 2020)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension."2.66The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease. ( Lim, JS; Rainey, WE, 2020)
"Hypokalemia is closely linked with the pathophysiology of primary aldosteronism (PA)."2.66Hypokalemia and the Prevalence of Primary Aldosteronism. ( Beuschlein, F; Gruber, S, 2020)
"Unilateral aldosteronism may also be due to multiple CYP11B2-expressing nodules of various sizes or a continuous band of hyperplastic ZG cells expressing CYP11B2."2.66Immunohistochemistry of the Human Adrenal CYP11B2 in Normal Individuals and in Patients with Primary Aldosteronism. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP; Nishimoto, K, 2020)
"Primary aldosteronism is the most common form of secondary hypertension with a prevalence of 5-10% in hypertensive patients."2.66The landscape of molecular mechanism for aldosterone production in aldosterone-producing adenoma. ( Gomez-Sanchez, CE; Oki, K, 2020)
"Primary aldosteronism, the excessive production of the steroid hormone aldosterone, is the most common cause of secondary hypertension."2.61[Primary aldosteronism : Genetics and pathology]. ( Scholl, U, 2019)
"The term 'idiopathic hyperaldosteronism' may soon become obsolete."2.61Immunohistochemistry for aldosterone synthase CYP11B2 and matrix-assisted laser desorption ionization imaging mass spectrometry for in-situ aldosterone detection. ( Mukai, K; Mune, T; Nishimoto, K; Nishiyama, M; Sugiura, Y; Terada, Y; Zhang, Z, 2019)
"Primary aldosteronism is the most common form of secondary hypertension."2.58Overview of aldosterone-related genetic syndromes and recent advances. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2018)
"Untreated patients with primary aldosteronism showed an impaired physical and mental HRQoL as compared to the general population."2.55Health-Related Quality of Life and Mental Health in Primary Aldosteronism: A Systematic Review. ( Burgers, VWG; de Nooijer, AH; Deinum, J; Hermus, ARMM; Husson, O; Lenders, JWM; Timmers, HJLM; Velema, MS, 2017)
"Primary aldosteronism (PA) significantly increases the risk of cardiovascular complications, and early diagnosis and targeted treatment based on its pathophysiology is warranted."2.55Aldosterone-Producing Cell Clusters in Normal and Pathological States. ( Omata, K; Rainey, WE; Tomlins, SA, 2017)
"Primary aldosteronism is the most common type of secondary hypertension affecting 6-10% of patients with primary hypertension."2.55Disordered CYP11B2 Expression in Primary Aldosteronism. ( Gomez-Sanchez, CE; Kuppusamy, M; Reincke, M; Williams, TA, 2017)
"Familial hyperaldosteronism has been with us for 50 years, and somatic mutations responsible for aldosterone producing adenomas for five."2.55Genetic disorders in primary aldosteronism-familial and somatic. ( Funder, JW, 2017)
"Hyperaldosteronism is the leading cause of secondary hypertension with up to 80% due to APA, statistically the most common functioning adrenal nodule."2.55Radiofrequency ablation treatment for aldosterone-producing adenomas. ( Faintuch, S; Sacks, AC; Sacks, BA, 2017)
"Primary aldosteronism (PA) is caused by excessive production of aldosterone by the adrenal cortex and is determined by a benign aldosterone-producing adenoma (APA) in a significant proportion of cases."2.53Local Control of Aldosterone Production and Primary Aldosteronism. ( Barhanin, J; Lalli, E; Warth, R; Zennaro, MC, 2016)
"Primary aldosteronism (PA), characterized by the inappropriate and abnormal adrenal secretion of aldosterone, is the most common cause of secondary hypertension."2.53Hyperaldosteronism: How to Discriminate Among Different Disease Forms? ( Buffolo, F; Burrello, J; Crudo, V; Monticone, S; Mulatero, P; Tetti, M; Veglio, F, 2016)
"Primary aldosteronism is the most common form of secondary hypertension and affects 8-13% of patients with hypertension."2.53Genetics of primary hyperaldosteronism. ( Dutta, RK; Gimm, O; Söderkvist, P, 2016)
"Primary aldosteronism (PA) is the most common and curable form of secondary hypertension."2.52An update on novel mechanisms of primary aldosteronism. ( Boulkroun, S; Fernandes-Rosa, F; Zennaro, MC, 2015)
"Primary aldosteronism is one of the commonly identified causes of hypertension and is treatable and/or potentially curable."2.52Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension. ( Ardhanari, S; Chaudhary, K; Kannuswamy, R; Lockette, W; Whaley-Connell, A, 2015)
"Primary aldosteronism (PA) is characterized by autonomic aldosterone production, usually leading to severe hypertension and hypokalaemia."2.52[Primary aldosteronism: new insights into familial forms]. ( Claahsen van der Grinten, HL; Danser, AH; Deinum, J; van den Meiracker, AH; van der Linde, AA, 2015)
"Aldosterone plays a major role in the regulation of sodium and potassium homeostasis and blood pressure."2.49Genetics of mineralocorticoid excess: an update for clinicians. ( Boulkroun, S; Rickard, AJ; Zennaro, MC, 2013)
"The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension."2.49Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism. ( Weiner, ID, 2013)
"Primary aldosteronism is the commonest form of hormone-related hypertension, with an estimated prevalence of 6-13% in the generalpopulation of hypertensive patients."2.49Primary aldosteronism - recent progress and current concepts. ( Januszewicz, A; Januszewicz, W; Kołodziejczyk-Kruk, S; Pęczkowska, M; Prejbisz, A; Zgliczyński, W, 2013)
"Primary hyperaldosteronism (PHA) is characterized by an increased Aldosterone synthesis which is independent of the Renin-Angiotensin-Aldosterone-System (RAAS)."2.48[Primay hyperaldosteronism--diagnostic and treatment]. ( Beuschlein, F; Potthoff, SA; Vonend, O, 2012)
"Primary Aldosteronism (PA) is a disorder of the adrenal zona glomerulosa (ZG) in which aldosterone secretion is increased and is relatively autonomous of normal regulatory mechanisms."2.46Progress in primary aldosteronism: present challenges and perspectives. ( Fallo, F; Gomez-Sanchez, CE; Mannelli, M; Rossi, GP, 2010)
"Primary hyperaldosteronism has historically been underdiagnosed as a cause of hypertension, but recent reports highlight its ubiquitous nature with a prevalence of 5%-10% in screened hypertensive patients."2.46Adrenal vein sampling. ( Angle, JF; Kahn, SL, 2010)
"Primary aldosteronism (PA) and, in particular, its two commonest subtypes (i."2.44Medical treatment as an alternative to adrenalectomy in patients with aldosterone-producing adenomas. ( Athyros, VG; Harsoulis, F; Kakafika, AI; Karagiannis, A; Mikhailidis, DP; Tziomalos, K, 2008)
"We present a case of oncocytic adrenocortical carcinoma in a 25-year-old man who presented with persistent hypertension, hypokalemia, and a large right adrenal mass."2.44Functional oncocytic adrenocortical carcinoma. ( Ali, AE; Raphael, SJ, 2007)
"Primary hyperaldosteronism (PHA), autonomic secretion of aldosterone by the adrenal gland, is rare."2.42[Primary hyperaldosteronism]. ( Deinum, J; van den Meiracker, AH, 2003)
"Primary aldosteronism is the most common form of secondary hypertension."2.42Recent advances in diagnosis and treatment of primary aldosteronism. ( Leotta, G; Morello, F; Mulatero, P; Rabbia, F; Veglio, F, 2003)
"Microscopically, a glucagonoma, measuring 2."2.40A rare combination consisting of primary hyperaldosteronism and glucagonoma. ( Abe, H; Kimura, W; Kubota, K; Makuuchi, M; Noie, T, 1999)
"Thus, primary aldosteronism represents one of a few potentially curable forms of hypertension."2.38Cellular origin of aldosteronomas. ( Ganguly, A, 1992)
"Primary aldosteronism is frequently caused by an adrenocortical aldosterone-producing adenoma (APA) carrying a somatic mutation that drives aldosterone overproduction."1.91Primary Aldosteronism: Spatial Multiomics Mapping of Genotype-Dependent Heterogeneity and Tumor Expansion of Aldosterone-Producing Adenomas. ( Blum, H; Gong, S; Koupourtidou, C; Krebs, S; Masserdotti, G; Meyer, LS; Rainey, WE; Reincke, M; Sun, N; Tetti, M; Walch, A; Williams, TA, 2023)
"His aldosterone/renin ratio was high and plasma renin activity was low."1.91[A Case of Aldosterone-Producing Adrenocortical Carcinoma]. ( Asai, S; Hashimoto, K; Ishihara, M; Kanamaru, S; Katsushima, H; Nakayasu, R; Oshiro, H; Shimizu, Y; Son, C; Tsuji, K; Utsunomiya, N, 2023)
"Primary aldosteronism (PA) is the most common form of endocrine hypertension and is characterized by inappropriately elevated aldosterone production via a renin-independent mechanism."1.91Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism. ( Bandulik, S; Blinder, AR; Else, T; Giordano, TJ; Kosmann, C; Kumar-Sinha, C; Lerario, AM; Nanba, K; Plain, A; Rainey, WE; Rege, J; Reincke, M; Sasano, H; Satoh, F; Turcu, AF; Udager, AM; Vats, P; Warth, R; Williams, TA; Yamazaki, Y, 2023)
"Aldosterone was positively associated with PTH levels (r = 0."1.72Association Between Aldosterone and Parathyroid Hormone Levels in Patients With Adrenocortical Tumors. ( Altieri, P; Balacchi, C; Borghi, C; Cosentino, ER; Di Cintio, I; Di Dalmazi, G; Golfieri, R; Malandra, J; Mosconi, C; Pagotto, U; Pelusi, C; Vicennati, V; Zavatta, G, 2022)
"Primary aldosteronism (PA) is the most common type of secondary hypertension, and it is associated with a higher rate of cardiovascular complications."1.72KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma. ( Chang, CC; Chang, YY; Chen, ZW; Chiu, YW; Chou, CH; Huang, JZ; Hung, CS; Kang, VJ; Lee, BC; Liao, CW; Lin, YH; Lin, YL; Pan, CT; Tsai, CH; Wu, VC, 2022)
"Adrenocortical carcinoma is a heterogeneous and aggressive cancer that originates from steroidogenic cells within the adrenal cortex."1.72A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma. ( Abate, A; Berruti, A; Bornstein, SR; Bothou, C; Cosentini, D; Hantel, C; Peitzsch, M; Penton, D; Sigala, S; Tiberio, GAM, 2022)
"Primary aldosteronism is mainly caused by APAs or idiopathic hyperaldosteronism (IHA)."1.72Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution. ( Gomez-Sanchez, CE; Horiuchi, Y; Iwahashi, N; Kosaka, T; Mukai, K; Nishimoto, K; Ogawa, Y; Oya, M; Seki, M; Seki, T; Suematsu, M; Suzuki, Y; Umakoshi, H; Umezawa, Y, 2022)
"However, adrenocortical carcinomas (ACC) and primary aldosteronism (PA) are rare in MEN1."1.72Genetic Dissection of Primary Aldosteronism in a Patient With MEN1 and Ipsilateral Adrenocortical Carcinoma and Adenoma. ( Bourdeau, I; Corbeil, G; Duranceau, C; El-Haffaf, Z; Karakiewicz, PI; Lacroix, A; Latour, M; Parisien-La Salle, S, 2022)
"In primary aldosteronism (PA), aldosterone secretion is relatively independent of the renin-angiotensin system, but can be regulated by several other stimuli."1.62Aldosterone is Aberrantly Regulated by Various Stimuli in a High Proportion of Patients with Primary Aldosteronism. ( Bourdeau, I; Lacroix, A; Martin, M; St-Jean, M, 2021)
"Accurate subtyping of the primary aldosteronism into aldosterone-producing adenoma (APA) and idiopathic adrenal hyperplasia (IAH) is important to direct for specific treatment modalities."1.56A clinical prediction score using age at diagnosis and saline infusion test parameters can predict aldosterone-producing adenoma from idiopathic adrenal hyperplasia. ( Chan, KW; Fong, CHY; Lau, EYF; Leung, HT; Leung, JYY; Tan, KCB; Woo, YC, 2020)
"Primary aldosteronism, which is usually caused by an aldosterone-producing tumour, affects glucose metabolism."1.56Insulin secretion and sensitivity before and after surgical treatment for aldosterone-producing adenoma. ( Fukuoka, H; Hirota, Y; Iguchi, G; Komada, H; Nakamura, T; Ogawa, W; Okuno, Y; Sakaguchi, K; So, A; Takahashi, Y, 2020)
"Aldosterone-producing adrenocortical adenomas (APAs) are mainly composed of clear (lipid rich) and compact (eosinophilic) tumor cells."1.56Histological Characterization of Aldosterone-producing Adrenocortical Adenomas with Different Somatic Mutations. ( Beuschlein, F; Carling, T; Else, T; Ito, S; Monticone, S; Mulatero, P; Omata, K; Ono, Y; Rainey, WE; Reincke, M; Rhayem, Y; Sasano, H; Satoh, F; Tomlins, SA; Williams, TA; Yamazaki, Y, 2020)
"Correct subtyping of primary aldosteronism (PA) is critical for guiding clinical management."1.56The Concordance Between Imaging and Adrenal Vein Sampling Varies With Aldosterone-Driver Somatic Mutation. ( Caoili, E; Nanba, A; Nanba, K; Rainey, WE; Shields, JJ; Turcu, AF; Wannachalee, T, 2020)
"Non-classic congenital adrenal hyperplasia was diagnosed initially; however, genetic testing revealed no 21-hydroxylase deficiency."1.56Adrenal Tumor Mimicking Non-Classic Congenital Adrenal Hyperplasia. ( Dai, SH; Tsai, CH; Tsai, WH; Wong, CH; Zeng, YH, 2020)
"Four out of 25 patients with primary hyperaldosteronism failed dexamethasone suppression tests."1.51The relevance of cortisol co-secretion from aldosterone-producing adenomas. ( Bhatt, PS; Meeran, KM; Salem, V; Sam, AH, 2019)
"APA cause primary aldosteronism (PA), which affect 3-10% of the hypertensive population."1.51Aldosterone-Producing Adenomas. ( Åkerström, T; Björklund, P; Hellman, P, 2019)
"The adrenal glands with adrenocortical adenomas from 79 black patients with primary aldosteronism were studied."1.51Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks. ( Barletta, JA; Cohen, DL; Demidowich, AP; Else, T; Gellert, L; Giordano, TJ; Gomez-Sanchez, CE; Luther, JM; Nanba, K; Omata, K; Rainey, WE; Stratakis, CA; Suzuki, M; Thompson, LDR; Tomlins, SA; Vaidya, A, 2019)
"In addition, primary aldosteronism (PA) is clinically associated with not only more frequent cardiovascular events but also secondary metabolic disorders including abnormal calcium metabolism, osteoporosis and others."1.51The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant "neoplastic" steroidogenesis in adrenals. ( Gao, X; Morimoto, R; Nakamura, Y; Ogata, H; Omata, K; Onodera, Y; Sasano, H; Satoh, F; Tezuka, Y; Yamazaki, Y, 2019)
"In patients with KCNJ5-mutated APA, left ventricular hypertrophy was significantly decreased by surgical treatment in patients from either Cured or Improved groups, although those patients with wild-type KCNJ5 showed no change."1.48KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma. ( Kitamoto, T; Nishikawa, T; Omura, M; Saito, J; Suematsu, S, 2018)
"Nonfunctioning adrenocortical adenoma (n = 12) and APA (n = 35) samples were analyzed."1.48Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma. ( Gomez-Sanchez, CE; Hattori, N; Itcho, K; Kobuke, K; Ohno, H; Oki, K; Yoneda, M; Yoshii, Y, 2018)
"The mechanism of aldosterone-producing adrenocortical adenoma (APA) pathogenesis and the role of microRNAs (miRNAs) in APA pathogenesis have not been completely clarified."1.48MiR-193a-3p functions as a tumour suppressor in human aldosterone-producing adrenocortical adenoma by down-regulating CYP11B2. ( Huang, R; Kang, H; Lai, C; Liu, Q; Xie, T; Zhang, G; Zhu, J; Zou, X, 2018)
"Primary aldosteronism (PA) represents the most frequent form of endocrine hypertension."1.48Cortisol Excess in Patients With Primary Aldosteronism Impacts Left Ventricular Hypertrophy. ( Adolf, C; Arlt, W; Beuschlein, F; Bidlingmaier, M; Franke, A; Heinrich, DA; Köhler, A; Ladurner, R; Lang, K; Löw, A; Reincke, M; Riester, A; Treitl, M, 2018)
"Primary aldosteronism is a common cause of hypertension, which becomes refractory if undiagnosed, but potentially curable when caused by an aldosterone-producing adenoma (APA)."1.46Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin). ( Brown, MJ; Garg, S; Gomez-Sanchez, CE; Gurnell, M; Johnson, TI; Teo, AE; Zhao, W; Zhou, J, 2017)
"Primary hyperaldosteronism is a common cause of hypertension in the adult population."1.46A case of confirmed primary hyperaldosteronism diagnosed despite normal screening investigations. ( Carroll, R; Feltham, J; Gould, A; Harper, S, 2017)
"Subclinical hypercortisolism (SH) occurs in 5% to 30% of adrenal incidentalomas (AIs)."1.46Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas. ( Annamalai, AK; Dennedy, MC; Freeman, N; Graggaber, J; Gurnell, M; Halsall, DJ; Koulouri, O; Powlson, AS; Prankerd-Smith, O; Shaw, A; Vengopal, K, 2017)
"The tumor was a benign adrenocortical adenoma composed predominantly of clear cells positive for 17α-hydroxylase, [hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerases], and aldosterone synthase."1.43Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism. ( Aizawa, T; Komatsu, M; Matsushita, T; Nakasone, Y; Nishikawa, T; Oguchi, K; Okubo, Y; Sasano, H; Sato, Y; Shirotori, K; Yamauchi, K; Yamazaki, Y, 2016)
"Aldosterone-producing adrenocortical carcinoma is a rare malignancy, which is usually diagnosed by histopathological examination of the excised tumor."1.43Aldosterone-producing adrenocortical carcinoma with prominent hepatic metastasis diagnosed by liver biopsy: a case report. ( Ebisawa, T; Hayashi, T; Iuchi, H; Ohashi, K; Sakamoto, M; Sasano, H; Suzuki, H; Tojo, K; Utsunomiya, K, 2016)
"Normotensive hyperaldosteronism is a rare disorder."1.43A Woman with Normotensive Primary Hyperaldosteronism. ( Amirbaigloo, A; Moradi, S; Shafiepour, M, 2016)
"Primary aldosteronism was confirmed by using the oral sodium-loading test."1.43Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation-Long-term Results and Recurrence Rate. ( Chiu, PW; Chow, FC; Chu, CC; Kong, AP; Liu, SY; Ng, EK; Tsui, TK; Wong, SK, 2016)
"Unilateral primary aldosteronism (PA) should have a contralaterally normal and therefore suppressed adrenal zona glomerulosa."1.42Defining contralateral adrenal suppression in primary aldosteronism: implications for diagnosis and outcome. ( Chin, A; Harvey, A; Kline, GA; Pasieka, JL; So, B, 2015)
"If detected in patients with primary aldosteronism could implicate prorenin in the development of primary aldosteronism."1.42Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism. ( Belloni, AS; Caroccia, B; Ceolotto, G; Gonzales-Campos, A; Lenzini, L; Nussberger, J; Petrelli, L; Rainey, WE; Recarti, C; Rossi, GP; Seccia, TM, 2015)
"Hyperkalemia was defined as serum potassium >5."1.42Clinical risk factors of postoperative hyperkalemia after adrenalectomy in patients with aldosterone-producing adenoma. ( Choi, SH; Hong, AR; Kim, JH; Kim, SW; Kim, SY; Ku, EJ; Moon, MK; Park, KS; Shin, CS, 2015)
"Although primary aldosteronism is associated with more prominent cardiac remodeling and diastolic dysfunction, the reversibility of diastolic function is unclear."1.42Circulating tissue inhibitor of matrix metalloproteinase-1 is associated with aldosterone-induced diastolic dysfunction. ( Chang, YS; Chang, YY; Chen, MF; Chen, YH; Chou, CH; Ho, YL; Hung, CS; Lin, YH; Su, MJ; Tsai, YC; Wu, KD; Wu, VC; Wu, XM, 2015)
"Primary aldosteronism affects 6% of hypertensive patients."1.42[Primary aldosteronism]. ( Amar, L, 2015)
"Primary aldosteronism is the most common form of secondary hypertension."1.42Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma. ( Amar, L; Boulkroun, S; Fernandes-Rosa, FL; Giscos-Douriez, I; Gomez-Sanchez, CE; Meatchi, T; Zennaro, MC, 2015)
"Primary aldosteronism (PA, also Conn syndrome) is a benign disease in majority of cases."1.40Predictors of malignancy in primary aldosteronism. ( Agha, A; Haneya, A; Hornung, M; Iesalnieks, I; Jung, EM; Schlitt, HJ; Schreyer, A, 2014)
"Primary aldosteronism (PA) is the main cause of secondary hypertension, resulting from adrenal aldosterone-producing adenomas (APA) or bilateral hyperplasia."1.40WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production. ( Amar, L; Assié, G; Batisse-Lignier, M; Bertherat, J; Berthon, A; Boulkroun, S; Drelon, C; Lefèbvre, H; Lefrançois-Martinez, AM; Martinez, A; Plateroti, M; Plouin, PF; Ragazzon, B; Sahut-Barnola, I; Samson-Couterie, B; Skah, S; Tissier, F; Val, P; Zennaro, MC, 2014)
"The molecular mechanisms of primary aldosteronism, a common cause of human hypertension, are unknown, but alterations of K(+) channels can play a key role."1.40Lower expression of the TWIK-related acid-sensitive K+ channel 2 (TASK-2) gene is a hallmark of aldosterone-producing adenoma causing human primary aldosteronism. ( Bader, M; Belloni, AS; Campos, AG; Caroccia, B; Fassina, A; Ferraro, S; Kuppusamy, M; Lenzini, L; Rainey, WE; Rossi, GP; Seccia, TM; Skander, G, 2014)
"Primary aldosteronism (autonomous aldosterone production with suppressed renin) plays an important pathophysiological role in what has been previously labeled as essential hypertension."1.40Role for germline mutations and a rare coding single nucleotide polymorphism within the KCNJ5 potassium channel in a large cohort of sporadic cases of primary aldosteronism. ( Gordon, RD; Massimo, G; Murthy, M; O'Shaughnessy, KM; Stowasser, M; Wolley, M; Xu, S, 2014)
"From 257 consecutive primary aldosteronism patients, we identified 176 who had both a diagnosis of APA by the 'four corners' criteria and high-quality echocardiographic data."1.40KCNJ5 gene somatic mutations affect cardiac remodelling but do not preclude cure of high blood pressure and regression of left ventricular hypertrophy in primary aldosteronism. ( Cesari, M; Cicala, MV; Iacobone, M; Kuppusamy, M; Letizia, C; Mantero, F; Mareso, S; Pessina, AC; Rossi, GP; Sciomer, S; Seccia, TM; Zinnamosca, L, 2014)
"Primary aldosteronism is the most common form of secondary hypertension."1.40Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma. ( Allolio, B; Amar, L; Bernini, G; Beuschlein, F; Boulkroun, S; Cicala, MV; Fallo, F; Fernandes-Rosa, FL; Giacchetti, G; Jeunemaitre, X; Maccario, M; Mantero, F; Meatchi, T; Monticone, S; Mulatero, P; Quinkler, M; Reincke, M; Riester, A; Steichen, O; Strom, TM; Williams, TA; Zennaro, MC, 2014)
"Although primary aldosteronism (PA) is the most common cause of endocrine hypertension, histopathological methods to reveal the presence and sites of aldosterone overproduction remain to be established."1.39Histopathological diagnosis of primary aldosteronism using CYP11B2 immunohistochemistry. ( Katabami, T; Kawa, G; Mukai, K; Nanba, K; Naruse, M; Nishimoto, K; Okumura, A; Okuno, H; Sawai, K; Shimatsu, A; Tagami, T; Tanabe, A; Tsuiki, M; Usui, T; Yamamoto, T, 2013)
"Hyperkalemia is a potentially serious complication following adrenalectomy of aldosterone-producing adenomas (APA)."1.39Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma. ( Cheng, CJ; Chiang, WF; Lin, MY; Lin, SH; Sun, GH; Sung, CC; Wu, ST, 2013)
"Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases."1.38Aldosterone-producing adrenocortical carcinoma without hypertension. ( Bae, SB; Kim, SJ; Kim, YJ; Seo, SW; Song, MS, 2012)
"Insulin resistance in primary aldosteronism might occur in compartments other than fat and/or depend on concurrent environmental factors."1.36Analysis of insulin sensitivity in adipose tissue of patients with primary aldosteronism. ( Calcagno, A; Fallo, F; Giacchetti, G; Giorgino, F; Gomez-Sanchez, C; Hubert, EL; Mulatero, P; Peschechera, A; Pilon, C; Sonino, N; Toffanin, M; Urbanet, R; Vettor, R; Zennaro, MC, 2010)
"Primary aldosteronism is the most common form of secondary hypertension with hypokalemia and suppressed renin-angiotensin system caused by autonomous aldosterone production."1.36Adrenal cortex remodeling and functional zona glomerulosa hyperplasia in primary aldosteronism. ( Amar, L; Benecke, A; Boulkroun, S; Dzib, JF; Jeunemaitre, X; Lalli, E; Lefebvre, H; Louiset, E; Meatchi, T; Plouin, PF; Samson-Couterie, B; Zennaro, MC, 2010)
"The diagnosis of primary hyperaldosteronism due to microadenoma or unilateral adrenal hyperplasia can be challenging, since hypokalaemic alkalosis, high plasma aldosterone and a definite adenoma on imaging may all be absent."1.35Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension. ( Appleton, DS; Brown, MJ; Coghill, S; Jamieson, N; Lomas, DJ; Myint, KS; Taylor, KP; Watts, M, 2008)
"Aldosterone secretion was stimulated by GIP in primary cultures of this patient's aldosteronoma."1.35Regulation of aldosterone secretion by several aberrant receptors including for glucose-dependent insulinotropic peptide in a patient with an aldosteronoma. ( Arjane, P; Bourdeau, I; Godbout, A; Hamet, P; Lacroix, A; Lampron, A; Oble, S; Schürch, W, 2009)
"Findings suggested that primary hyperaldosteronism should be considered as a possible cause in ferrets with hypokalemia, hypertension, and an adrenal gland mass."1.35Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma. ( Desmarchelier, M; Dunn, M; Lair, S; Langlois, I, 2008)
"Normokalaemia does not exclude primary aldosteronism as the underlying cause of hypertension."1.35[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009]. ( Guthoff, M; Horger, M; Kirchhoff, K; Kurth, R; Müssig, K; Schnauder, G, 2009)
"Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia."1.35An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. ( Ahmetoğlu, A; Bahat, E; Imamoğlu, M; Karagüzel, G; Okten, A; Yildiz, K, 2009)
"Laboratory data suggested primary aldosteronism (PA)."1.35Primary aldosteronism due to unilateral adrenal microadenoma in an elderly patient: efficacy of selective adrenal venous sampling. ( Adachi, J; Araki, A; Chiba, Y; Horiuchi, T; Ito, H; Kasuya, Y; Mori, S; Murayama, T; Sasano, H; Sawabe, M; Takeda, K; Tamura, Y, 2008)
"Primary aldosteronism (PA) is a common curable disease of secondary hypertension."1.35Bilateral aldosterone-producing adenomas: differentiation from bilateral adrenal hyperplasia. ( Chang, HW; Chueh, SC; Hsieh, BS; Li, HY; Lin, WC; Lin, YH; Liu, KL; Wu, KD; Wu, VC, 2008)
"Primary hyperaldosteronism is described in a 27-year-old Brazilian woman from an endemic area of schistosomiasis."1.34Clinics in diagnostic imaging (113). ( Costa, AF; dos Santos, VM; Resurreição, FM; Vieira, MT, 2007)
"Primary aldosteronism (PA) represents an important cause of secondary hypertension, potentially curable, and it has been receiving particular attention due to its increasing prevalence, after the beginning of the use of plasma aldosterone concentration to plasma renin activity ratio as a screening method."1.34[Primary aldosteronism caused by aldosteronoma: problems in the etiologic diagnosis]. ( Brandão Neto, RA; Danilovic, DL; Freire, DS; Lucon, AM; Paraíba, DB; Pereira, MA, 2007)
"There is a high prevalence for primary hyperaldosteronism (PHA) in hypertensive patients."1.34[Comparison of adrenal imaging and selective adrenal vein sampling in primary hyperaldosteronism]. ( Adams, S; Hahn, K; Kokulinsky, P; Liermann, D; Rump, LC; Stegbauer, J; Vonend, O, 2007)
"Treatment with mitotane was instituted and successful for a period of 4-months until the dog was euthanatized for neurologic problems that were most likely unrelated to endocrine disease."1.33Corticosterone- and aldosterone-secreting adrenocortical tumor in a dog. ( Behrend, EN; Kemppainen, RJ; Refsal, KR; Weigand, CM; Whitley, EM; Young, DW, 2005)
"Primary aldosteronism is the most common form of mineralocorticoid hypertension."1.33[Diagnosis and treatment outcome in primary aldosteronism based on a retrospective analysis of 187 cases]. ( Dabasi, G; Füto, L; Gláz, E; Horányi, J; Jakab, C; Járay, J; Kiss, R; Major, L; Molnár, F; Patócs, A; Perner, F; Rácz, K; Szücs, N; Tóth, M; Tulassay, Z; Varga, I, 2006)
"Primary aldosteronism is the most common endocrine form of secondary hypertension, but no single test or imaging method always identifies it."1.33The role of adrenal venous sampling in the surgical management of primary aldosteronism. ( Bernante, P; Pelizzo, MR; Rossi, GP; Toniato, A, 2006)
"Exploratory laparotomy revealed adrenocortical carcinoma."1.33Unusual visualization of an adrenal carcinoma on NP-59 scintiscan. ( Chang, YH; Pan, CC; Tu, DG; Wang, FF; Won, JG, 2006)
"The clinical data of 267 patients of primary hyperaldosteronism with adrenal adenoma confirmed by operation 1995 - 2005 were analyzed."1.33[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore]. ( Li, HZ; Pan, DL; Yan, QZ, 2006)
"The association of Conn's syndrome with Behcet's disease was thought to be coincidental."1.32Conn's syndrome associated with Behcet's disease. ( Kim, YA; Lee, SS, 2003)
"The aldosterone peak level was significantly higher in APAs [mean +/- SEM: 84."1.32Functional and nonfunctional adrenocortical tumors demonstrate a high responsiveness to low-dose adrenocorticotropin. ( Arnaldi, G; Kola, B; Mancini, T; Mantero, F, 2003)
"Aortic dissection is a rare but severe disease."1.32[Primary aldosteronism. A risk factor for aortic dissection?]. ( Blacher, J; Kesri, L; Mourad, JJ; Safar, M; Tartière, JM, 2003)
"We report a rare case of adrenocortical carcinoma."1.32Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. ( Azizlerli, H; Kapran, Y; Kurtulmus, N; Yarman, S, 2004)
"Patients with familial adenomatous polyposis (FAP) frequently have extracolonic manifestations of their disease."1.31Primary aldosteronism in a patient with familial adenomatous polyposis. ( Alexander, GL; Schwartz, DA; Thompson, GB, 2000)
"Metyrapone inhibition was associated with a concomitant increase in the formation of androgens (androstenedione and testosterone) from pregnenolone."1.31Biosynthesis and metabolism of steroid hormones by human adrenal carcinomas. ( Brown, JW; Fishman, LM, 2000)
"The hypertension of Conn's syndrome is due to autonomous aldosterone production by a unilateral adrenocortical adenoma."1.31Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome). ( Connell, JM; Davies, E; Fraser, R; Friel, EC; Inglis, GC; Plouin, PF, 2001)
"Primary aldosteronism is classified as aldosterone-producing adenoma (APA), idiopathic hyperaldosteronism (IHA), unilateral adrenal hyperplasia (UAH), primary adrenal hyperplasia (PAH), adrenal cancer, and glucocorticoid-remediable aldosteronism."1.31Unique cases of unilateral hyperaldosteronemia due to multiple adrenocortical micronodules, which can only be detected by selective adrenal venous sampling. ( Fujiwara, T; Nishikawa, T; Omura, M; Sasano, H; Yamaguchi, K, 2002)
"Primary aldosteronism very rarely develops to malignant hypertension, and even in that case ARC is suppressed."1.30Malignant hypertension in a patient with primary aldosteronism with elevated active renin concentration. ( Fujiwara, K; Hayashi, K; Nakazato, T; Oka, K; Saruta, T; Suzawa, T, 1997)
"Primary aldosteronism consists of a mixture of subgroups."1.30Adrenalectomy for primary aldosteronism: long-term follow-up study in 29 patients. ( Haapiainen, R; Huikuri, K; Sirén, J; Sivula, A; Välimäki, M; Voutilainen, P, 1998)
"By contrast, myelolipomas (23+/-20) ganglioneuromas (43+/-15) and a hemangioma (11 pg/mg cytosolic protein) had very low p53 protein content."1.30p53 protein and its messenger ribonucleic acid in human adrenal tumors. ( Adleff, V; Bezzegh, A; Gláz, E; Rácz, K; Tóth, M; Varga, I, 1998)
"Although primary aldosteronism is rare, especially during pregnancy, it should be always considered as one of etiologies of hypertension in pregnancy."1.30Primary aldosteronism with aldosterone-producing adrenal adenoma in a pregnant woman. ( Fujiyama, S; Inada, M; Iwasaka, T; Maruyama, K; Masaki, H; Matsubara, H; Matsuda, T; Mori, Y; Nagata, T; Okada, S; Umeda, Y; Yonemoto, T, 1999)
"Ventricular fibrillation has not previously been described as a presention of a biochemically and surgically proven aldosterone-producing adenoma."1.30Ventricular fibrillation: an extreme presentation of primary hyperaldosteronism. ( Abdo, A; Bebb, RA; Wilkins, GE, 1999)
"Dexamethasone-sensitive hyperaldosteronism is associated with early onset hypertension and primary hyperaldosteronism."1.29[Hyperaldosteronism sensitive to dexamethasone with adrenal adenoma. Clinical, biological and genetic study]. ( Aupetit-Faisant, B; Charru, A; Corvol, P; Guyene, TT; Jeunemaitre, X; Pascoe, L; Plouin, PF; Schambelan, M; Shackleton, CH, 1995)
"In patients with primary aldosteronism due to aldosterone producing adenoma (APA) (n = 21) and Cushing's disease or syndrome (Cushing's disease n = 13; adrenocortical adenoma n = 10), plasma 18oxoF level early in the morning following an overnight fast was evaluated as well as plasma cortisol and aldosterone levels."1.29Plasma 18-oxocortisol levels in the patients with adrenocortical disorders. ( Gomez-Sanchez, CE; Miura, K; Morita, H; Mune, T; Yamakita, N; Yasuda, K, 1994)
"The aldosterone content was significantly elevated, while the androstenedione content was significantly decreased in the tumour portion of the adenoma compared with that in the normal control adrenals."1.29Significance of steroidogenic enzymes in the pathogenesis of adrenal tumour. ( Ishimura, Y; Ogishima, T; Saruta, T; Shibata, H; Suzuki, H, 1993)
"We report a case of primary hyperaldosteronism due to unilateral diffuse hyperplasia."1.29Unilateral diffuse adrenal hyperplasia masquerading as aldosterone-producing adenoma in primary hyperaldosteronism. ( Hashimoto, T; Ishigooka, M; Kato, T; Kubota, Y; Nakada, T; Sasagawa, I; Suzuki, H, 1993)
"A small subgroup of primary aldosteronism due to aldosteronoma, named aldosterone-producing renin-responsive adenoma (AP-RA), has been reported to masquerade as idiopathic hyperaldosteronism (IHA) because of the responsiveness of the plasma aldosterone concentration (PAC) to upright posture (UP)."1.29Characteristics of aldosterone-producing adenoma responsive to upright posture. ( Aiba, M; Demura, H; Kikuchi, C; Kono, A; Nomura, K; Ogasawara, M; Toraya, S, 1995)
"Primary aldosteronism (PA) is caused by an adrenal aldosterone-producing tumor (A-APT) or adrenal hyperplasia."1.29Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients. ( Abdelhamid, S; Bönhof, JA; Müller-Lobeck, H; Pahl, S; Remberger, K; Röckel, A; Walb, D, 1996)
"In control subjects and patients with Conn's syndrome, the DOC:B ratio was not affected by ACTH."1.29Altered 11 beta-hydroxylase activity in glucocorticoid-suppressible hyperaldosteronism. ( Connell, JM; Davies, E; Fraser, R; Inglis, GC; Ingram, MC; Jamieson, A, 1996)
"Aldosterone was secreted from the adrenal cortex in all patients and was increased by ACTH in 75% of the tissue specimens."1.28Basal and ACTH-stimulated cortisol and aldosterone release from adrenocortical adenomas in vitro. ( Grimelius, L; Gröndal, S; Hamberger, B; Thorén, M, 1991)
"Twenty patients with primary hyperaldosteronism had endocrinologic and radiologic studies to distinguish aldosterone-producing adenoma from idiopathic hyperaldosteronism due to bilateral micro- or macronodular hyperplasia of the adrenal cortex."1.28Diagnosis of primary hyperaldosteronism: importance of correlating CT findings with endocrinologic studies. ( Manoogian, C; Nadler, JL; Radin, DR, 1992)
"The aldosterone content was significantly higher in adrenocortical adenomas than in normal adrenal glands, while F content in adenomas was similar to the level in normal adrenal glands."1.28Expression of cytochrome P-450 mRNAs in steroidogenesis of adrenocortical adenomas from patients with primary aldosteronism. ( Haji, M; Nawata, H; Ogo, A; Ohashi, M, 1991)
"A peculiar form of hyperaldosteronism is the glucocorticoid-remediable subtype."1.28New aspects of mineralocorticoid hypertension. ( Armanini, D; Biason, A; Boscaro, M; Carpenè, G; Fallo, F; Mantero, F; Opocher, G; Rocco, S; Scaroni, C; Sonino, N, 1990)
"We have reported a case of Conn's syndrome, with pain, tenderness, and swelling of the calf mimicking deep vein thrombophlebitis."1.28Conn's syndrome with rhabdomyolysis mimicking deep vein thrombophlebitis. ( Mahdyoon, H; Mermiges, DN; Wisgerhof, M, 1990)
"A male patient presenting with primary hyperaldosteronism after a three-year delay, was found to have an aldosterone producing adrenocortical carcinoma."1.27Carcinoma of the adrenal cortex causing primary hyperaldosteronism. A case report and review of the literature. ( Schaberg, A; Slee, PH; Van Brummelen, P, 1983)
"Although secondary hyperaldosteronism due to renal vein thrombosis may occur as a result of renal cell carcinoma or adrenal cortical carcinoma, primary hyperaldosteronism is rarely associated with the latter."1.27Adrenal cortical carcinoma: an unusual cause of hyperaldosteronism. ( Telner, AH, 1983)
"A definite diagnosis of primary aldosteronism cannot be made during toxemia of pregnancy, and it is necessary to do serial determinations of plasma renin activity and plasma aldosterone concentration after delivery to confirm the diagnosis."1.27Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism. ( Akahoshi, M; Aoi, W; Doi, Y; Hashiba, K; Kuramochi, M; Shimizu, A; Suzuki, S; Utsunomiya, T, 1983)
"A 7-year-old girl had hyperaldosteronism due to an adrenal cortical adenoma, a rare, surgically remediable cause of hypertension."1.27Hypertension caused by an aldosterone-secreting adenoma. Occurrence in a 7-year-old child. ( Bryer-Ash, M; Luetscher, JA; Rosenfeld, RG; Shochat, SJ; Tune, BM; Wilson, DM, 1984)
"Four patients with idiopathic aldosteronism all had an increase in plasma aldosterone levels after 5HTP administration, whereas the response in four patients with aldosterone-producing adenoma was variable."1.27Central serotonergic stimulation of aldosterone secretion. ( Grekin, RJ; Gross, MD; Shenker, Y, 1985)
"Cushing's syndrome is the consequence of a sustained overproduction of cortisol (hydrocortisone) by the adrenal cortex."1.27Diagnosis and pathophysiology of Cushing's syndrome. ( Gabrilove, JL; Krakoff, LR, 1986)
"Out of 100 cases of tumoral primary aldosteronism studied from 1977 to 1987, we observed 4 ACC and 96 Conn's adenomas (CONN)."1.27[Malignant adrenal cortex carcinoma revealed by an isolated picture of primary hyperaldosteronism]. ( Chatellier, G; Corvol, P; Farge, D; Pagny, JY; Plouin, PF, 1988)
"A 50-year old female with primary aldosteronism and masked hyperaldosteronemia is reported."1.27A case report of aldosterone producing adenoma with masked hyperaldosteronemia. ( Arimori, S; Hiramatsu, K; Takahashi, K, 1986)
"Hypertension is a common finding in patients with Cushing's syndrome (CS), but the cause is unknown."1.27Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome. ( Ehlers, ME; Griffing, GT; Melby, JC; Wilson, TE, 1987)
"A patient with primary aldosteronism had bilateral adrenal tumours on computed tomography."1.27False localization of an aldosteronoma by dexamethasone-suppressed adrenal scintigraphy. ( Davidson, JK; Fraser, R; Herd, GW; Hilditch, TE; Parker, D; Semple, PF, 1987)
"Primary aldosteronism, when caused by an aldosterone-producing adenoma, is a surgically treatable condition."1.26An aldosterone-producing adrenal cortical adenoma. ( Hugo, JM; Shipton, EA, 1982)
"Adrenocortical adenomas causing hyperaldosteronism in two women heterozygous at the X chromosome-linked glucose-6-phosphate dehydrogenase (G-6-PD) locus exhibited only one G-6-PD isoenzyme."1.26Probable clonal origin of aldosteronomas versus multicellular origin of parathyroid "adenomas". ( Block, MA; Cerny, JC; Fialkow, PJ; Jackson, CE, 1982)
"Aldosterone excretion was high, normal, or low in each of the three types of Cushing's syndrome."1.26Deoxycorticosterone and aldosterone excretion in Cushing's syndrome. ( Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K, 1980)
"In all of the 10 patients with primary aldosteronism, ACTH stimulated aldosterone secretion from the adenomas more significantly than did angiotensin II and III."1.26[Studies on the mechanism of secretion of adrenal steroid hormones from adenomas of primary aldosteronism and Cushing's syndrome (author's transl)]. ( Eguchi, T; Kondo, K; Matsuki, S; Murai, M; Nakamura, R; Oka, M; Okuno, T; Saito, I; Saruta, T; Yasui, T, 1980)
"These data show that patients with hyperaldosteronism from an adrenal adenoma or hyperplasia have a consistent and exaggerated response to ACTH."1.26Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kem, DC; Kramer, NJ; Weinberger, MH, 1978)
"The aldosterone production was normal and was produced solely by the adenoma."1.26Concurrent hypercortisolism and hypermineralocorticoidism. ( Biglieri, EG; Hogan, MJ; Schambelan, M, 1977)
"Twenty patients suffering from primary hyperaldosteronism were studied."1.26[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977)
"The probe continues."1.26A perspective on aldosterone abnormalities. ( Biglieri, EG, 1976)
"Hypokalemic hypertension is the leading symptome of the disease."1.26[Primary aldosteronism]. ( Beckerhoff, R; Braun, KP; Furrer, J; Nussberger, J; Pouliadis, G; Siegenthaler, W; Sobbe, A; Vetter, H; Vetter, W; Witassek, F, 1976)
"Two patient with primary aldosteronism, one with a solitary adrenal adenoma and the other with bilateral nodular hyperplasia, are described."1.25Primary aldosteronism. A study in contrasts. ( Espiner, EA; Hughes, H; Nicholls, MG; Ross, J; Stewart, DT, 1975)

Research

Studies (601)

TimeframeStudies, this research(%)All Research%
pre-1990144 (23.96)18.7374
1990's105 (17.47)18.2507
2000's106 (17.64)29.6817
2010's191 (31.78)24.3611
2020's55 (9.15)2.80

Authors

AuthorsStudies
Zavatta, G1
Di Dalmazi, G2
Altieri, P1
Pelusi, C1
Golfieri, R1
Mosconi, C1
Balacchi, C1
Borghi, C1
Cosentino, ER1
Di Cintio, I1
Malandra, J1
Pagotto, U3
Vicennati, V2
Wang, H1
Wang, F2
Zhang, Y5
Wen, J1
Dong, D1
Chang, X1
Sun, H1
Ma, X3
Cui, Y1
Chen, S1
Lu, L1
Ren, W1
Tong, A1
Li, Y1
De Sousa, K3
Abdellatif, AB4
Giscos-Douriez, I4
Meatchi, T8
Amar, L13
Fernandes-Rosa, FL11
Boulkroun, S19
Zennaro, MC22
Gao, X3
Li, F1
Liu, B1
Wang, Y6
Zhou, H1
Motomura, N2
Yamazaki, Y13
Tezuka, Y8
Omata, K11
Ono, Y9
Morimoto, R13
Satoh, F21
Nakamura, Y15
Shim, J1
Choi, MH2
Ito, A3
Sasano, H33
Lee, BC2
Kang, VJ1
Pan, CT1
Huang, JZ1
Lin, YL1
Chang, YY2
Tsai, CH2
Chou, CH2
Chen, ZW1
Liao, CW1
Chiu, YW1
Wu, VC9
Hung, CS2
Chang, CC3
Lin, YH7
Shu, Q1
Deng, M1
Chen, Y1
Liu, N1
Cai, L1
Harashima, S1
Suzuki, H7
Kwon, GE1
Sigala, S1
Bothou, C1
Penton, D2
Abate, A1
Peitzsch, M5
Cosentini, D1
Tiberio, GAM1
Bornstein, SR4
Berruti, A1
Hantel, C1
Nanba, K11
Baker, JE1
Blinder, AR4
Bick, NR1
Liu, CJ1
Lim, JS2
Wachtel, H2
Cohen, DL3
Williams, TA18
Reincke, M30
Lyden, ML1
Bancos, I1
Young, WF2
Else, T7
Giordano, TJ6
Udager, AM3
Rainey, WE26
Iwahashi, N1
Umakoshi, H1
Seki, T5
Gomez-Sanchez, CE27
Mukai, K8
Suematsu, M3
Umezawa, Y1
Oya, M2
Kosaka, T2
Seki, M1
Suzuki, Y1
Horiuchi, Y1
Ogawa, Y4
Nishimoto, K8
Pitsava, G1
Faucz, FR2
Stratakis, CA4
Hannah-Shmouni, F2
van Rooyen, D1
Baliga, R1
Le Floch, E1
Cosentino, T1
Larsen, CK1
Beuschlein, F23
Rossi, GP25
Baron, S2
Chantalat, S1
Saintpierre, B1
Lenzini, L7
Frouin, A1
Ferey, M1
Empana, JP1
Jouven, X1
Gieger, C1
Waldenberger, M1
Peters, A1
Cusi, D1
Salvi, E1
Meneton, P1
Touvier, M1
Deschasaux, M1
Druesne-Pecollo, N1
Deleuze, JF1
Jeunemaitre, X5
Porubayeva, EE1
Pachuashvili, NV1
Urusova, LS1
Parisien-La Salle, S1
Corbeil, G2
El-Haffaf, Z1
Duranceau, C1
Latour, M2
Karakiewicz, PI1
Lacroix, A4
Bourdeau, I4
Ali, Y1
Gomez-Sanchez, EP9
Gong, S5
Tetti, M5
Kemter, E3
Mulatero, P16
Bidlingmaier, M7
Eisenhofer, G5
Wolf, E3
Zhang, X4
Lyu, Q1
Ma, J1
Pan, X1
Wei, Q1
Li, J3
Zhu, Y2
Shen, S1
Ou, Y1
Tong, N1
Ma, L2
Yang, S3
Yang, Y2
Chen, X1
Yang, J2
He, Y2
Cheng, Q2
Kang, B1
Tang, S1
Zhang, A1
Shu, X1
Li, X2
Shen, H1
Jing, Y1
Song, Y2
Li, Q3
Hu, J3
Zhao, L1
Wan, J1
Yang, W1
Liang, Q1
Wang, J1
Jin, P1
Sun, N3
Meyer, LS3
Koupourtidou, C1
Krebs, S1
Masserdotti, G1
Blum, H1
Walch, A2
Wu, X2
Azizan, EAB2
Goodchild, E2
Garg, S3
Hagiyama, M1
Cabrera, CP2
Kuan, JL2
Tiang, Z2
David, A1
Murakami, M4
Mein, CA2
Wozniak, E2
Zhao, W2
Marker, A2
Buss, F1
Saleeb, RS1
Salsbury, J1
Oki, K9
King, PJ1
Drake, WM2
Gurnell, M5
Ceral, J1
Ryska, A1
Mustangin, M1
Wong, YP1
Tan, GC1
Solar, M1
Foo, RS1
Takaoka, Y1
Murray, SA1
Brown, MJ6
Caroccia, B10
Seccia, TM14
Pallafacchina, G2
Piazza, M3
Caputo, I1
Zamberlan, S1
Rizzuto, R2
Oshiro, H1
Shimizu, Y1
Nakayasu, R1
Utsunomiya, N1
Son, C1
Tsuji, K1
Asai, S1
Katsushima, H1
Ishihara, M2
Hashimoto, K5
Kanamaru, S1
Rege, J1
Bandulik, S2
Kosmann, C1
Plain, A1
Vats, P1
Kumar-Sinha, C1
Lerario, AM3
Turcu, AF4
Warth, R6
Bhatt, PS1
Sam, AH1
Meeran, KM1
Salem, V1
Rhayem, Y5
Kunzke, T2
Feuchtinger, A2
Ludwig, P1
Strom, TM4
Gomez-Sanchez, C5
Knösel, T2
Kirchner, T1
Walch, AK1
Leung, HT1
Woo, YC1
Fong, CHY1
Tan, KCB1
Lau, EYF1
Chan, KW1
Leung, JYY1
Komada, H1
Hirota, Y1
So, A1
Nakamura, T1
Okuno, Y1
Fukuoka, H1
Iguchi, G1
Takahashi, Y1
Sakaguchi, K1
Ogawa, W1
Ichijo, T1
Ueshiba, H1
Nawata, H7
Yanase, T3
Scholl, U1
Tomlins, SA5
Carling, T4
Monticone, S8
Ito, S10
Wack, M1
Rocha, A1
Travers, S1
Tömböl, Z1
Turai, PI1
Decmann, Á1
Igaz, P1
Gruber, S1
Kamilaris, CDC1
Guo, Z1
Udager, A1
McWhinney, BC1
Ungerer, JPJ1
Wolley, M2
Thuzar, M1
Gordon, RD9
Stowasser, M5
Wannachalee, T1
Caoili, E1
Nanba, A1
Shields, JJ1
Kishimoto, S2
Maruhashi, T2
Kajikawa, M1
Hashimoto, H1
Takaeko, Y1
Harada, T1
Yamaji, T2
Han, Y1
Kihara, Y2
Chayama, K1
Goto, C1
Yusoff, FM1
Nakashima, A1
Higashi, Y2
Morandi, L1
Rubin, B1
Pilon, C6
Asioli, S2
De Leo, A1
Ambrosi, F1
Santini, D1
Maffeis, V1
Fassina, A6
Fallo, F12
Hussain, ZS1
Rao, SS1
Hussain, WZ1
Puzhakkal, S1
Łebek-Szatańska, A1
Nowak, KM1
Papierska, L1
St-Jean, M1
Martin, M1
Tsai, WH1
Wong, CH1
Dai, SH1
Zeng, YH1
Zhang, C3
Wu, L1
Jiang, L3
Su, T3
Zhou, W3
Zhong, X1
Xie, J2
Sun, F1
Jiang, Y3
Wang, W5
Pauzi, FA1
Azizan, EA3
Chen, KM1
Chang, YL1
Wu, TH1
Chen, PT1
Liu, KL3
Hong, JS1
Zhou, J2
Argentesi, G1
Cottrell, E1
O'Toole, S1
Senanayake, R1
Åkerström, T5
Backman, S2
Jordan, S1
Polubothu, S1
Berney, DM1
Gluck, A1
Lines, KE1
Thakker, RV1
Tuthill, A1
Joyce, C1
Kaski, JP1
Karet Frankl, FE1
Metherell, LA1
Teo, AED1
Parvanta, L1
Klinzing, D1
Gomez Sanchez, CE1
Hellman, P8
Foo, RSY1
Kinsler, VA1
Björklund, P7
Storr, HL1
Teo, AE1
Johnson, TI1
Carroll, R1
Gould, A1
Feltham, J1
Harper, S1
Vanderriele, PE2
Rossitto, G3
Battistel, M2
Barbiero, G2
Bisogni, V1
Maiolino, G2
Diego, M1
Zheng, FF2
Zhu, LM2
Zhou, WL2
Li, MY1
Zhu, YC2
Wang, JG2
Zhu, DL2
Gao, PJ2
Kitamoto, T3
Omura, M9
Suematsu, S3
Saito, J5
Nishikawa, T12
Scholl, UI5
Inoue, K3
Tsurutani, Y2
Sugisawa, C2
Kobuke, K2
Ohno, H2
Itcho, K2
Yoshii, Y2
Yoneda, M2
Hattori, N2
Lei, J1
Zhang, S1
Wang, P1
Liao, Y1
Bian, J1
Yin, X1
Wu, Y1
Bai, L1
Yang, X1
Liu, H1
Wang, B3
Tang, L1
Chen, L1
Gu, L1
Zhang, F1
Ouyang, J3
Velema, MS1
de Nooijer, AH1
Burgers, VWG1
Hermus, ARMM1
Timmers, HJLM1
Lenders, JWM2
Husson, O1
Deinum, J6
Kuppusamy, M4
Funder, JW5
Prejbisz, A2
van der Wilt, GJ1
Heinze, B1
Fuss, CT1
Mustafa, M1
Schirbel, A2
Deutschbein, T1
Quinkler, M4
Rayes, N1
Wild, V1
Reis, AC2
Petersenn, S1
Wester, HJ1
Kropf, S1
Fassnacht, M4
Lang, K3
Herrmann, K1
Buck, AK2
Bluemel, C1
Hahner, S2
Kiseljak-Vassiliades, K1
Bagby, SM1
Kar, A1
Pozdeyev, N1
Xu, M1
Gowan, K1
Sharma, V1
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Clinical Trials (14)

Trial Overview

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The Prevalence and Characteristics of Adrenal Incidentaloma: A Prospective Study[NCT04682938]25,356 participants (Actual)Observational2020-11-20Completed
Macrolides for KCNJ5 - Mutated Aldosterone-Producing Adenoma (MAPA): A Study Of Personalized Diagnosis of Primary Aldosteronism With Implications For Treatment[NCT03414918]342 participants (Anticipated)Interventional2018-03-31Not yet recruiting
Clinical Study of Chemokine Receptor 4 (CXCR4)-Mediated Precision Targeting of 18F for the Diagnosis of Aldosteronism in Primary Aldosteronism[NCT05815069]20 participants (Anticipated)Interventional2023-01-07Recruiting
68Ga-Pentixafor PET/CT for the Subtyping Diagnosis of Primary Aldosteronism: A Prospective Diagnostic Accuracy Study[NCT05131061]100 participants (Actual)Observational2021-11-11Completed
Effects of Mineralocorticoid and AT-1 Receptor Antagonism on the Aldosterone-Renin Ratio (ARR) In Primary Aldosteronism Patients (EMIRA Study): Rationale and Design[NCT04185857]50 participants (Actual)Observational2018-01-01Completed
Postoperative Cardiovascular Index Change of Primary Aldosteronism[NCT00746070]300 participants (Actual)Observational2007-01-31Enrolling by invitation
Resident Doctor, Master Degree Candidate[NCT05991856]45 participants (Anticipated)Observational2020-01-01Recruiting
A Phase 1 Clinical Trial Evaluating the Safety and Efficacy of up to Two Administrations of the Adrenal PET Tracer [18F]CETO in Healthy Volunteers and Patients With Primary Aldosteronism[NCT04529018]11 participants (Anticipated)Interventional2020-08-03Recruiting
Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism[NCT01990560]Phase 48 participants (Actual)Interventional2013-11-30Completed
Usefulness of the Ipsilateral and Contralateral Index for the Interpretation of Adrenal Vein Sampling (AVS) in the Subtype Diagnosis of Primary Aldosteronism[NCT04378387]60 participants (Actual)Observational2005-01-01Completed
Prospective Cross-sectional Study on Prevalence of Primary Aldosteronism in Resistant Hypertension and Association With Cardiometabolic Complications[NCT04213963]100 participants (Anticipated)Observational2011-09-01Recruiting
The Intra-Procedural Cortisol Assay During Adrenal Vein Sampling: Rationale andDesign of A Randomized Study (I-PADUA)[NCT03449797]200 participants (Anticipated)Interventional2018-04-01Not yet recruiting
[NCT00451672]Phase 425 participants Interventional2007-01-31Recruiting
Multicenter Study on Use and Interpretation of Adrenal Vein Sampling[NCT01234220]2,604 participants (Actual)Observational2010-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

A1C Level

Change in hyperglycemia assessed by HbA1c, also known as glycated hemoglobin (NCT01990560)
Timeframe: Baseline, 3 months, and 6 months

Interventionpercentage of red blood cells (Mean)
Baseline3 months6 months
Mifepristone6.26.13756.125

Body Mass Index (BMI)

Change in metabolic syndrome as assessed by BMI (NCT01990560)
Timeframe: Baseline and 6 months

Interventionkg/m2 (Mean)
Baseline6 months
Mifepristone35.153834.5463

CushingQoL

Change in Quality of Life - as assessed by the Cushing's Quality of Life questionnaire (CushingQoL). Patient completed questionnaire, 12 items, each scored on a 5 point score, resulting in a score of 12 (worst) to 60 (best) where higher scores indicate more favorable QOL. (NCT01990560)
Timeframe: Baseline and 6 months

Interventionunits on a scale (Mean)
Baseline6 months
Mifepristone37.285738.7857

Fasting Lipid Profile

Change in metabolic syndrome as assessed by fasting lipid profile which includes Low-density lipoproteins ( LDL), High-density lipoproteins (HDL), and Triglycerides (Trigs) levels, and total cholesterol which is the sum of HDL plus LDL and 20% of trigs. (NCT01990560)
Timeframe: Baseline and 6 months

Interventionmg/dL (Mean)
Total Cholesterol BaselineTotal Cholesterol 6 monthsLDL baselineLDL 6 monthsHDL BaselineHDL 6 monthsTrigs BaselineTrigs 6 months
Mifepristone178.63171.4397.88104.3759.1346.86107.88100.29

HOMA-IR

Change in hyperglycemia assessed by Homeostatic Model Assessment of Insulin Resistance, HOMA-IR (a validated assessment of insulin resistance). HOMA-IR = fasting insulin (microU/L) x fasting glucose (nmol/L)/22.5. (NCT01990560)
Timeframe: Baseline and 6 months

InterventionHOMA-IR score (Mean)
Baseline6 months
Mifepristone2.4181.465

Hospital Anxiety and Depression Scale (HADS)

Change in Quality of Life as assessed by the Hospital Anxiety and Depression Scale (HADS). Questionnaire with 7 items for anxiety and 7 items for depression, each item is scored on a 4 point response 0 - 3, with full range from 0 to 42, with higher score indicating more severe anxiety or depression (NCT01990560)
Timeframe: Baseline and 6 months

Interventionunits on a scale (Mean)
Baseline6 months
Mifepristone16.285711.1667

Nottingham Health Profile (NHP)

Change in Quality of Life as assessed by the Nottingham Health Profile (NHP) which is a patient reported questionnaire to measure a patient's view of their own health status. There are 6 sections (Energy level, Pain, Emotional Reaction, Sleep, Social Isolation, and Physical Abilities. All questions have only yes/no answer options and each section score is weighted so that the possible score range for any section is 0-100. The higher the score, the greater the number and severity of problems. (NCT01990560)
Timeframe: Baseline and 6 months

Interventionunits on a scale (Mean)
Energy Level (EL) BaselineEL 6 monthsPain (P) BaselineP 6 monthsEmotional Reaction (ER) BaselineER 6 monthsSleep (S) BaselineS 6 monthsSocial Isolation (SI) BaselineSI 6 monthsPhysical Abilities (PA) BaselinePA 6 months
Mifepristone32.6045.4024.8832.0827.0335.0924.8731.1520.0931.1523.0627.49

Quality of Life

Change in Quality of Life as assessed by the Beck Depression Inventory. a 21-question multiple choice, self-report inventory that is used for measuring the severity of anxiety. Scoring is from a 0 (not at all) to 3 (severe) with a total score range of 0-63. Higher total scores indicate more severe anxiety symptoms. (NCT01990560)
Timeframe: Baseline and 6 months

Interventionunits on a scale (Mean)
Baseline6 months
Mifepristone16.142911.7143

State Trait Anxiety Inventory (STAI)

Change in Quality of Life - as assessed by the State Trait Anxiety Inventory (STAI). The State-Trait Anxiety Inventory both state and trait anxiety separately. Each type of anxiety has its own scale of 20 different questions that are scored and averaged. Total scores range from 20 to 80, with higher scores correlating with greater anxiety. (NCT01990560)
Timeframe: Baseline and 6 months

Interventionunits on a scale (Mean)
Baseline6 months
Mifepristone25.428628.8571

Waist Circumference

Change in metabolic syndrome as assessed by waist circumference (NCT01990560)
Timeframe: Baseline and 6 months

Interventioncm (Mean)
Baseline6 months
Mifepristone103.2599.3125

Weight

Change in metabolic syndrome as assessed by weight (NCT01990560)
Timeframe: Baseline and 6 months

Interventionkg (Mean)
Baseline6 months
Mifepristone99.5797.75

Reviews

70 reviews available for aldosterone and Adrenal Cortex Cancer

ArticleYear
Cellular Senescence in Adrenocortical Biology and Its Disorders.
    Cells, 2021, 12-09, Volume: 10, Issue:12

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aging; Aldosterone; Androgens; Cellular Senescence; Humans

2021
Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas.
    Current cardiology reports, 2022, Volume: 24, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; G P

2022
Identification of risk loci for primary aldosteronism in genome-wide association studies.
    Nature communications, 2022, 09-03, Volume: 13, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Animals; DNA-Binding P

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
[Primary aldosteronism : Genetics and pathology].
    Der Pathologe, 2019, Volume: 40, Issue:Suppl 3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Mutation;

2019
Old and new genes in primary aldosteronism.
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Genetic Association Studies; Genetic

2020
MicroRNAs and Adrenocortical Tumors: Where do we Stand on Primary Aldosteronism?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertens

2020
Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II Type 1 Receptor Blocke

2020
The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cytoc

2020
Hypokalemia and the Prevalence of Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Disease Progression; Humans; Hyperald

2020
Immunohistochemistry of the Human Adrenal CYP11B2 in Normal Individuals and in Patients with Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cytoc

2020
Adrenocortical tumorigenesis: Lessons from genetics.
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:3

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Carcinogenesis; DNA Mutational Analysis; Gene

2020
The landscape of molecular mechanism for aldosterone production in aldosterone-producing adenoma.
    Endocrine journal, 2020, Oct-28, Volume: 67, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Calcium Channels, L-Type; Calcium Sig

2020
Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Factors; Aging; Aldosterone; H

2021
Review of Markers of Zona Glomerulosa and Aldosterone-Producing Adenoma Cells.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Animals; Biomarkers; Humans; Hyperaldosteronism; Sig

2017
Unanswered Questions in the Genetic Basis of Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:12

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; DNA Copy Num

2017
Health-Related Quality of Life and Mental Health in Primary Aldosteronism: A Systematic Review.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:12

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Health Status; Humans; Hyperaldoster

2017
Aldosterone-Producing Cell Clusters in Normal and Pathological States.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:12

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Humans; Hyperaldoste

2017
Disordered CYP11B2 Expression in Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:12

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Cytochrome P-450 CYP11B2; Gene Expre

2017
Overview of aldosterone-related genetic syndromes and recent advances.
    Current opinion in endocrinology, diabetes, and obesity, 2018, Volume: 25, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Factors; Aging; Aldosterone; C

2018
The Biology of Normal Zona Glomerulosa and Aldosterone-Producing Adenoma: Pathological Implications.
    Endocrine reviews, 2018, 12-01, Volume: 39, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aging; Aldosterone; Humans; Hyperaldosteronism; Zo

2018
Immunohistochemistry for aldosterone synthase CYP11B2 and matrix-assisted laser desorption ionization imaging mass spectrometry for in-situ aldosterone detection.
    Current opinion in nephrology and hypertension, 2019, Volume: 28, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B

2019
Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; beta Catenin; Calcium Channels, L-Typ

2019
Genetics of mineralocorticoid excess: an update for clinicians.
    European journal of endocrinology, 2013, Volume: 169, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Disease Models, Animal; G Pr

2013
Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Cell Membrane; G Prot

2013
Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.
    Seminars in nephrology, 2013, Volume: 33, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Eplerenone; Humans; Hy

2013
Primary aldosteronism - recent progress and current concepts.
    Endokrynologia Polska, 2013, Volume: 64, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2013
Aldosterone-secreting adrenal cortical carcinoma. A case report and review of the literature.
    Endocrine pathology, 2014, Volume: 25, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aged; Aldosterone; Female; Humans; Hyperaldoster

2014
Novel genes in primary aldosteronism.
    Current opinion in endocrinology, diabetes, and obesity, 2014, Volume: 21, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Calcium Channels, L-Type; Female; G P

2014
[Primary hyperaldosteronism: boundaries of diagnostics and therapy].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:40

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hyperfunction; Aldos

2014
An update on novel mechanisms of primary aldosteronism.
    The Journal of endocrinology, 2015, Volume: 224, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Calcium Channels, L-Type; G

2015
Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension.
    Advances in chronic kidney disease, 2015, Volume: 22, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; Aldosterone; Drug

2015
[Genetic alterations in primary aldosteronism].
    Medecine sciences : M/S, 2015, Volume: 31, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Calcium Channels, L-Type; G

2015
Adrenal steroidogenesis and congenital adrenal hyperplasia.
    Endocrinology and metabolism clinics of North America, 2015, Volume: 44, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; Aldosterone; Andr

2015
Adrenal incidentalomas: a disease of modern technology offering opportunities for improved patient care.
    Endocrinology and metabolism clinics of North America, 2015, Volume: 44, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adrenocortical Carcinoma;

2015
Adrenocortical carcinoma: review of the pathologic features, production of adrenal steroids, and molecular pathogenesis.
    Endocrinology and metabolism clinics of North America, 2015, Volume: 44, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Androgens; Estrogens; Humans; Hydro

2015
A Meta-Analysis of Somatic KCNJ5 K(+) Channel Mutations In 1636 Patients With an Aldosterone-Producing Adenoma.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:8

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; G Protein-Coupled Inwardly-Rectifying

2015
[Primary aldosteronism: new insights into familial forms].
    Nederlands tijdschrift voor geneeskunde, 2015, Volume: 159

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; DNA Mutational Analysis; G Protein-Co

2015
Local Control of Aldosterone Production and Primary Aldosteronism.
    Trends in endocrinology and metabolism: TEM, 2016, Volume: 27, Issue:3

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Gene Express

2016
Genetic disorders in primary aldosteronism-familial and somatic.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 165, Issue:Pt A

    Topics: Adenoma; Adenosine Triphosphatases; Adrenal Cortex Neoplasms; Adult; Aldosterone; Chimera; Female; G

2017
Hyperaldosteronism: How to Discriminate Among Different Disease Forms?
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Aldosterone; Biomarkers; Diagnos

2016
Genetics of primary hyperaldosteronism.
    Endocrine-related cancer, 2016, Volume: 23, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Animals; Genetic Pred

2016
Radiofrequency ablation treatment for aldosterone-producing adenomas.
    Current opinion in endocrinology, diabetes, and obesity, 2017, Volume: 24, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Catheter Ablation; Hum

2017
Medical treatment as an alternative to adrenalectomy in patients with aldosterone-producing adenomas.
    Endocrine-related cancer, 2008, Volume: 15, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldostero

2008
Progress in primary aldosteronism: present challenges and perspectives.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Endocrinolog

2010
Adrenal vein sampling.
    Techniques in vascular and interventional radiology, 2010, Volume: 13, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocort

2010
[Primay hyperaldosteronism--diagnostic and treatment].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:48

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; A

2012
[Primary hyperaldosteronism].
    Nederlands tijdschrift voor geneeskunde, 2003, Aug-16, Volume: 147, Issue:33

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Antihypertensive Agent

2003
A case of normoreninemic aldosterone-producing adenoma associated with chronic renal failure: case report and literature review.
    Endocrine, 2003, Volume: 21, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Circadia

2003
Recent advances in diagnosis and treatment of primary aldosteronism.
    Minerva medica, 2003, Volume: 94, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Biomarkers; Glucocorticoids; Humans;

2003
The clinically inapparent adrenal mass: update in diagnosis and management.
    Endocrine reviews, 2004, Volume: 25, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Bioma

2004
From incidentaloma to adrenocortical carcinoma: the surgical management of adrenal tumors.
    Journal of surgical oncology, 2005, Mar-01, Volume: 89, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adrenoco

2005
[Adrenocortical adenoma].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Androgens; Biomarkers;

2006
[Normokalemic primary hyperaldosteronism].
    Deutsche medizinische Wochenschrift (1946), 2006, Volume: 131, Issue:46 Spec No

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hype

2006
Functional oncocytic adrenocortical carcinoma.
    Endocrine pathology, 2007,Fall, Volume: 18, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aldosterone; Humans; Hydrocortisone; Male

2007
[Diagnostic tests for endocrine hypertension].
    Rinsho byori. The Japanese journal of clinical pathology, 1984, Volume: Spec No 58

    Topics: Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; A

1984
[Aldosterone producing tumor].
    Ryoikibetsu shokogun shirizu, 1993, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldostero

1993
[Aldosterone producing adenoma].
    Ryoikibetsu shokogun shirizu, 1993, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism

1993
Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature.
    European journal of pediatrics, 1994, Volume: 153, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Child; Female; Humans; Magnetic Reson

1994
Aldosterone-producing adrenocortical adenoma complicated by chronic renal failure. Case report and review of the literature.
    American journal of nephrology, 1998, Volume: 18, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Female;

1998
Primary aldosteronism.
    The New England journal of medicine, 1998, Dec-17, Volume: 339, Issue:25

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Humans; Hype

1998
A rare combination consisting of primary hyperaldosteronism and glucagonoma.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Carcinoma, Renal Cell; Glucagonoma; H

1999
Primary aldosteronism.
    The Urologic clinics of North America, 1977, Volume: 4, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism;

1977
Significance of renin and angiotensin in hypertension.
    Cardiovascular clinics, 1978, Volume: 9, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin I; Angiotensin II; Female; Humans; Hyper

1978
[Primary aldosteronism--aldosterone-induced sodium storing hypertension--symptoms and differential diagnosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Volume: 37, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Alkalosis; Animals; Diagnosis, Differential; Dogs; F

1979
Cellular origin of aldosteronomas.
    The Clinical investigator, 1992, Volume: 70, Issue:5

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism

1992
[The therapy of primary aldosteronism].
    Deutsche medizinische Wochenschrift (1946), 1992, Jun-12, Volume: 117, Issue:24

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Carcinoma; Dexamethasone; Humans; Hy

1992
Aldosterone-producing tumors (Conn's syndrome).
    Seminars in surgical oncology, 1990, Volume: 6, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Male; Mid

1990
Cytophysiology of the adrenal cortex.
    International review of cytology, 1986, Volume: 98

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms;

1986
[Clinical course, diagnosis and treatment of primary hyperaldosteronism].
    Klinicheskaia meditsina, 1974, Volume: 52, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cushing Syndrome; Diagnosis, Differential; Fe

1974

Trials

5 trials available for aldosterone and Adrenal Cortex Cancer

ArticleYear
Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Con Side of the Argument.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Blood

2018
Effect of Treatment on Body Fluid in Patients with Unilateral Aldosterone Producing Adenoma: Adrenalectomy versus Spironolactone.
    Scientific reports, 2015, Oct-19, Volume: 5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aged; Aged, 80 and over; Aldosteron

2015
Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Carbon Radioisotopes; Etomidat

2012
Somatic mutations in the KCNJ5 gene raise the lateralization index: implications for the diagnosis of primary aldosteronism by adrenal vein sampling.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Female; Functional La

2012
Characterization of serotonin(4) receptors in adrenocortical aldosterone-producing adenomas: in vivo and in vitro studies.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cisapride; Female; Humans; In Vitro Technique

2002

Other Studies

526 other studies available for aldosterone and Adrenal Cortex Cancer

ArticleYear
Association Between Aldosterone and Parathyroid Hormone Levels in Patients With Adrenocortical Tumors.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2022, Volume: 28, Issue:1

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Calcium; Humans; Hyperaldosteronism; Parathyroid Hormone; Ret

2022
Surgical Outcomes of Aldosterone-Producing Adenoma on the Basis of the Histopathological Findings.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Femal

2021
Colocalization of Wnt/β-Catenin and ACTH Signaling Pathways and Paracrine Regulation in Aldosterone-producing Adenoma.
    The Journal of clinical endocrinology and metabolism, 2022, 01-18, Volume: 107, Issue:2

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aldos

2022
Visualization of calcium channel blockers in human adrenal tissues and their possible effects on steroidogenesis in the patients with primary aldosteronism (PA).
    The Journal of steroid biochemistry and molecular biology, 2022, Volume: 218

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Amlodipine; Calcium Channel Blockers;

2022
KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Aorta; Calcinosis; G Protein

2022
Imaging Aldosterone-Producing Adrenocortical Carcinoma With 68 Ga-Pentixafor PET/CT.
    Clinical nuclear medicine, 2022, Aug-01, Volume: 47, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Coordination Complexes; Humans; Pep

2022
Phenotype-genotype correlation in aldosterone-producing adenomas characterized by intracellular cholesterol metabolism.
    The Journal of steroid biochemistry and molecular biology, 2022, Volume: 221

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; G Protein-Coupled Inwardly-R

2022
A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma.
    Cells, 2022, 04-24, Volume: 11, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldoste

2022
Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults.
    The Journal of clinical endocrinology and metabolism, 2022, 08-18, Volume: 107, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Calcium Channels, L-T

2022
Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution.
    The Journal of clinical endocrinology and metabolism, 2022, 08-18, Volume: 107, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Hum

2022
Primary aldosteronism caused by a pI157S somatic
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Child; Female; G

2022
[Multifactorial assessment of prognostic features of adrenocortical cancer].
    Arkhiv patologii, 2022, Volume: 84, Issue:5

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aged, 80 and over; Aldo

2022
Genetic Dissection of Primary Aldosteronism in a Patient With MEN1 and Ipsilateral Adrenocortical Carcinoma and Adenoma.
    The Journal of clinical endocrinology and metabolism, 2022, 12-17, Volume: 108, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adrenocortical C

2022
Mammalian Target of Rapamycin Inhibition Decreases Angiotensin II-Induced Steroidogenesis in HAC15 Human Adrenocortical Carcinoma Cells.
    Endocrinology, 2022, 11-14, Volume: 164, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Angiotensin II; Humans; Hydrocortis

2022
TSPAN12 (Tetraspanin 12) Is a Novel Negative Regulator of Aldosterone Production in Adrenal Physiology and Aldosterone-Producing Adenomas.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Animals; Hum

2023
TSPAN12 (Tetraspanin 12) Is a Novel Negative Regulator of Aldosterone Production in Adrenal Physiology and Aldosterone-Producing Adenomas.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Animals; Hum

2023
TSPAN12 (Tetraspanin 12) Is a Novel Negative Regulator of Aldosterone Production in Adrenal Physiology and Aldosterone-Producing Adenomas.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Animals; Hum

2023
TSPAN12 (Tetraspanin 12) Is a Novel Negative Regulator of Aldosterone Production in Adrenal Physiology and Aldosterone-Producing Adenomas.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Animals; Hum

2023
Clinical characteristics and pre-surgery diagnostic criteria of aldosterone-producing adrenocortical carcinoma.
    Chinese medical journal, 2022, 10-20, Volume: 135, Issue:20

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Humans

2022
Phosphoproteomics Reveals the Wolframin-Calcium Axis as an Important Pathogenic Signaling Node in Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Calcium; Calcium Signaling;

2023
Different cell compositions and a novel somatic
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Cushing Syndrome; Cyt

2023
Primary Aldosteronism: Spatial Multiomics Mapping of Genotype-Dependent Heterogeneity and Tumor Expansion of Aldosterone-Producing Adenomas.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Antioxidants; Cytochrome P-4

2023
Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.
    Nature genetics, 2023, Volume: 55, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cell Adhesion Molecule-1; Cytochrome

2023
Aldosterone Biosynthesis Is Potently Stimulated by Perfluoroalkyl Acids: A Link between Common Environmental Pollutants and Arterial Hypertension.
    International journal of molecular sciences, 2023, May-27, Volume: 24, Issue:11

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Alkanesulfonic Acids; Cytochrome P-450 CYP11B2; Environmental

2023
[A Case of Aldosterone-Producing Adrenocortical Carcinoma].
    Hinyokika kiyo. Acta urologica Japonica, 2023, Volume: 69, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Humans; Male; Middle Aged; Mitotane

2023
Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism.
    Nature genetics, 2023, Volume: 55, Issue:10

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cation Transport Proteins; G

2023
The relevance of cortisol co-secretion from aldosterone-producing adenomas.
    Hormones (Athens, Greece), 2019, Volume: 18, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Dexamethasone; Diagnostic Tech

2019
In situ metabolomics of aldosterone-producing adenomas.
    JCI insight, 2019, 09-05, Volume: 4, Issue:17

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Calcium Channels, L-T

2019
A clinical prediction score using age at diagnosis and saline infusion test parameters can predict aldosterone-producing adenoma from idiopathic adrenal hyperplasia.
    Journal of endocrinological investigation, 2020, Volume: 43, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Age Factors; Aldosterone; Female; Humans; H

2020
Insulin secretion and sensitivity before and after surgical treatment for aldosterone-producing adenoma.
    Diabetes & metabolism, 2020, Volume: 46, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Blood Glucose; Female; G

2020
A nationwide survey of adrenal incidentalomas in Japan: the first report of clinical and epidemiological features.
    Endocrine journal, 2020, Feb-28, Volume: 67, Issue:2

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adrenocortica

2020
Histological Characterization of Aldosterone-producing Adrenocortical Adenomas with Different Somatic Mutations.
    The Journal of clinical endocrinology and metabolism, 2020, 03-01, Volume: 105, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Calcium Channels, L-Type; Fema

2020
Mass Spectrometry Imaging Establishes 2 Distinct Metabolic Phenotypes of Aldosterone-Producing Cell Clusters in Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Cell Division; Cytochrome P-450 CYP11B2; Fourier Ana

2020
Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cytochro

2020
Not All Hypertension Is a Lifelong Disease: A Teachable Moment.
    JAMA internal medicine, 2020, 05-01, Volume: 180, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agent

2020
Biochemical, Histopathological, and Genetic Characterization of Posture-Responsive and Unresponsive APAs.
    The Journal of clinical endocrinology and metabolism, 2020, 09-01, Volume: 105, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers, Tumor; Cohor

2020
The Concordance Between Imaging and Adrenal Vein Sampling Varies With Aldosterone-Driver Somatic Mutation.
    The Journal of clinical endocrinology and metabolism, 2020, 10-01, Volume: 105, Issue:10

    Topics: Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adu

2020
A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma.
    The Journal of clinical endocrinology and metabolism, 2020, 11-01, Volume: 105, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure;

2020
DNA Methylation of Steroidogenic Enzymes in Benign Adrenocortical Tumors: New Insights in Aldosterone-Producing Adenomas.
    The Journal of clinical endocrinology and metabolism, 2020, 12-01, Volume: 105, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cohort Studies; Cross-Se

2020
Potassium losing, aldosterone producing adrenocortical carcinoma: a rare presentation.
    BMJ case reports, 2020, Sep-09, Volume: 13, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosteron

2020
Pitfalls in the diagnostics of aldosterone-producing adrenocortical carcinoma.
    Endokrynologia Polska, 2020, Volume: 71, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Male; Middle Aged; Tomography

2020
Aldosterone is Aberrantly Regulated by Various Stimuli in a High Proportion of Patients with Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2021, 01-01, Volume: 106, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Diagnost

2021
Adrenal Tumor Mimicking Non-Classic Congenital Adrenal Hyperplasia.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocortical Adenoma; Ad

2020
KCNJ5 Mutation Contributes to Complete Clinical Success in Aldosterone-Producing Adenoma: A Study From a Single Center.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2021, Volume: 27, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Female; G Protein-Cou

2021
Aldosterone-producing adenoma-harbouring KCNJ5 mutations is associated with lower prevalence of metabolic disorders and abdominal obesity.
    Journal of hypertension, 2021, 12-01, Volume: 39, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; G Protein-Coupled Inwardly-Rectifying

2021
Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause.
    Nature genetics, 2021, Volume: 53, Issue:9

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; beta Catenin; Fema

2021
Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin).
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Cytochrome P-450 CYP11B2; Extracellular Matri

2017
A case of confirmed primary hyperaldosteronism diagnosed despite normal screening investigations.
    The New Zealand medical journal, 2017, May-12, Volume: 130, Issue:1455

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertens

2017
Aldosterone-Producing Adenomas: Genotypes and Phenotypes.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Genotype; Humans; Hyperaldosteronism; Phenotype

2017
The subtyping of primary aldosteronism by adrenal vein sampling: sequential blood sampling causes factitious lateralization.
    Journal of hypertension, 2018, Volume: 36, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2018
A novel somatic mutation 145-147delETEinsK in KCNJ5 increases aldosterone production.
    Journal of human hypertension, 2017, Volume: 31, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Biomarkers, Tumor; Calcium; Female; G

2017
KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma.
    Journal of hypertension, 2018, Volume: 36, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; G Prote

2018
Evaluation of Cortisol Production in Aldosterone-Producing Adenoma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Dexa

2017
Calneuron 1 Increased Ca
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocortical Carcinoma; Adult; Aldosterone; Anim

2018
Long-term presence of angiotensin II type 1 receptor autoantibody reduces aldosterone production by triggering Ca
    Immunologic research, 2018, Volume: 66, Issue:1

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Autoantibodies; Autoantigens; Calcium; Calcium Channels; Calc

2018
GSTA1 Expression Is Correlated With Aldosterone Level in KCNJ5-Mutated Adrenal Aldosterone-Producing Adenoma.
    The Journal of clinical endocrinology and metabolism, 2018, 03-01, Volume: 103, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Calcium; Cytochrome P-450 CYP1

2018
Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Pro Side of the Argument.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Austra

2018
Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:2

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldostero

2018
Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:2

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldostero

2018
Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:2

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldostero

2018
Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:2

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldostero

2018
Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma.
    The Journal of clinical endocrinology and metabolism, 2018, 03-01, Volume: 103, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Calcium Signaling; Calmodulin;

2018
Development of new preclinical models to advance adrenocortical carcinoma research.
    Endocrine-related cancer, 2018, Volume: 25, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Cell Line, Tumor; C

2018
The angiotensin type 2 receptor in the human adrenocortical zona glomerulosa and in aldosterone-producing adenoma: low expression and no functional role.
    Clinical science (London, England : 1979), 2018, 03-30, Volume: 132, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II Type 1 Receptor Blocke

2018
Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma.
    Human pathology, 2018, Volume: 77

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Female; Gene Expressi

2018
A Novel High-Resolution Magnetic Resonance Imaging Protocol Detects Aldosterone-Producing Adenomas in Patients With Negative Computed Tomography.
    American journal of hypertension, 2018, 07-16, Volume: 31, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers, Tumor; Diffu

2018
MiR-193a-3p functions as a tumour suppressor in human aldosterone-producing adrenocortical adenoma by down-regulating CYP11B2.
    International journal of experimental pathology, 2018, Volume: 99, Issue:2

    Topics: 3' Untranslated Regions; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Apoptosis; B

2018
Genetic Characterization of GnRH/LH-Responsive Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2018, 08-01, Volume: 103, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Case-Control Studies; DN

2018
Aldosterone Suppression by Dexamethasone in Patients With KCNJ5-Mutated Aldosterone-Producing Adenoma.
    The Journal of clinical endocrinology and metabolism, 2018, 09-01, Volume: 103, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; A

2018
Robot-assisted Partial Adrenalectomy for the Treatment of Conn's Syndrome: Surgical Technique, and Perioperative and Functional Outcomes.
    European urology, 2019, Volume: 75, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure;

2019
Targeted Molecular Characterization of Aldosterone-Producing Adenomas in White Americans.
    The Journal of clinical endocrinology and metabolism, 2018, 10-01, Volume: 103, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Calcium Channel

2018
miRNA-203 Modulates Aldosterone Levels and Cell Proliferation by Targeting Wnt5a in Aldosterone-Producing Adenomas.
    The Journal of clinical endocrinology and metabolism, 2018, 10-01, Volume: 103, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Apoptosis; Biomarkers, Tumor

2018
Cortisol Excess in Patients With Primary Aldosteronism Impacts Left Ventricular Hypertrophy.
    The Journal of clinical endocrinology and metabolism, 2018, 12-01, Volume: 103, Issue:12

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone;

2018
Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat.
    Veterinary clinical pathology, 2018, Volume: 47, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Animals; Biopsy; Ca

2018
Tumor Cell Subtypes Based on the Intracellular Hormonal Activity in KCNJ5-Mutated Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Fema

2018
Aldosterone-Producing Adenomas.
    Vitamins and hormones, 2019, Volume: 109

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Genetic Predisposition to Disease; Hu

2019
Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Black or African Amer

2019
Genetics of aldosterone-producing adenomas with pathogenic KCNJ5 variants.
    Endocrine-related cancer, 2019, 04-01, Volume: 26, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; G Protein-Couple

2019
The Key Role of CT for Success of Adrenal Venous Sampling Illustrated by a Unique Clinical Case.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2019, Volume: 26, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Biomar

2019
18-Oxocortisol Synthesis in Aldosterone-Producing Adrenocortical Adenoma and Significance of KCNJ5 Mutation Status.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; DNA Mutational Analysis; DNA, Neoplas

2019
CaseReport: Aldosterone-secreting adrenal carcinoma complicating longstanding hypertension.
    Journal of human hypertension, 2020, Volume: 34, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Carcinoma; Humans; H

2020
Aldosterone Stimulates Its Biosynthesis Via a Novel GPER-Mediated Mechanism.
    The Journal of clinical endocrinology and metabolism, 2019, 12-01, Volume: 104, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Benzodioxoles; Calcium; Canrenone; Cy

2019
Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency.
    Internal medicine (Tokyo, Japan), 2019, Nov-01, Volume: 58, Issue:21

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension, Mal

2019
H-score of 11β-hydroxylase and aldosterone synthase in the histopathological diagnosis of adrenocortical tumors.
    Endocrine, 2019, Volume: 65, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aldosterone; Cell Nucleus;

2019
The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant "neoplastic" steroidogenesis in adrenals.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 193

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Calcium;

2019
Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.
    Nature genetics, 2013, Volume: 45, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Calcium; Cells, Cultured; Electrophys

2013
Histopathological diagnosis of primary aldosteronism using CYP11B2 immunohistochemistry.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:4

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aged; Aldoste

2013
[¹²³I]Iodometomidate imaging in adrenocortical carcinoma.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:7

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aldosterone; Cohort

2013
Morphologic change in computed tomography of aldosterone-producing adenoma after radiofrequency ablation.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 2014, Volume: 65, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aged, 80 and over; Aldosterone; Catheter Ablation; C

2014
Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma.
    Clinica chimica acta; international journal of clinical chemistry, 2013, Sep-23, Volume: 424

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H

2013
MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:3

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Cell Line; Cytochrome P-450 CYP11B2;

2013
Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism.
    Nature genetics, 2013, Volume: 45, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Amino Acid Sequence; Calcium Channels

2013
Lack of influence of somatic mutations on steroid gradients during adrenal vein sampling in aldosterone-producing adenoma patients.
    European journal of endocrinology, 2013, Volume: 169, Issue:5

    Topics: Adenosine Triphosphatases; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Fac

2013
Predictors of malignancy in primary aldosteronism.
    Langenbeck's archives of surgery, 2014, Volume: 399, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Aged; Aldosterone; Cell Transformation, Neoplastic; Female;

2014
Somatic ATP1A1, ATP2B3, and KCNJ5 mutations in aldosterone-producing adenomas.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Fema

2014
Ins and outs of aldosterone-producing adenomas of the adrenal: from channelopathy to common curable cause of hypertension.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Female; G Protein-Coupled Inwardly-Re

2014
WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.
    Human molecular genetics, 2014, Feb-15, Volume: 23, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Animals; Cell Line, Tumor; Cyt

2014
Complementary somatic mutations of KCNJ5, ATP1A1, and ATP2B3 in sporadic aldosterone producing adrenal adenomas.
    Endocrine-related cancer, 2014, Volume: 21, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Base Sequence; Female; G

2014
A marked proportional rise in IVC aldosterone following cosyntropin administration during AVS is a signal to the presence of adrenal hyperplasia in primary aldosteronism.
    Journal of human hypertension, 2014, Volume: 28, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone;

2014
Lower expression of the TWIK-related acid-sensitive K+ channel 2 (TASK-2) gene is a hallmark of aldosterone-producing adenoma causing human primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Cells, Cultured; Down-Regulation; Gene Expression Pr

2014
PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues.
    Journal of molecular endocrinology, 2014, Volume: 52, Issue:2

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Blotting, Western; C

2014
Role for germline mutations and a rare coding single nucleotide polymorphism within the KCNJ5 potassium channel in a large cohort of sporadic cases of primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aldosterone; Amino Acid Sequence; Animals

2014
Integrated analysis of genome-wide methylation and gene expression shows epigenetic regulation of CYP11B2 in aldosteronomas.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; CpG Islands; Cytochrome

2014
MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas.
    European journal of endocrinology, 2014, Volume: 170, Issue:4

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aged, 80

2014
Channels and pumps in aldosterone-producing adenomas.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Potassium Channels, Tand

2014
Adrenal nodularity and somatic mutations in primary aldosteronism: one node is the culprit?
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aged; Aldosterone; DNA Muta

2014
KCNJ5 gene somatic mutations affect cardiac remodelling but do not preclude cure of high blood pressure and regression of left ventricular hypertrophy in primary aldosteronism.
    Journal of hypertension, 2014, Volume: 32, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Female; Follow-Up Studies; G Protein-

2014
Different expression of 11β-hydroxylase and aldosterone synthase between aldosterone-producing microadenomas and macroadenomas.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Blood Pressure; Cytochro

2014
Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Age Factors; Aldosterone; Calcium Channels,

2014
Adrenal cortical scintigraphy for lateralization of bilateral adrenal nodules in primary aldosteronism.
    Korean journal of urology, 2014, Volume: 55, Issue:8

    Topics: Adosterol; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aged; Al

2014
Aldosterone- and cortisol-co-producing adrenal adenoma without clinical features of Cushing syndrome.
    The Korean journal of internal medicine, 2014, Volume: 29, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Cushing Syndrom

2014
Defining contralateral adrenal suppression in primary aldosteronism: implications for diagnosis and outcome.
    Clinical endocrinology, 2015, Volume: 83, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Cohort Studies

2015
Activating transcription factor 3 (ATF3) in the human adrenal cortex: its possible involvement in aldosterone biosynthesis.
    The Tohoku journal of experimental medicine, 2014, Volume: 234, Issue:4

    Topics: Activating Transcription Factor 3; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; C

2014
Mast cell hyperplasia is associated with aldosterone hypersecretion in a subset of aldosterone-producing adenomas.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Cell Count; Cell Proliferation; Cells, Cultured; Gen

2015
KCNJ5 mutations are the most frequent genetic alteration in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Asian People; Female; Humans; Male; M

2015
Clinical characteristics of somatic mutations in Chinese patients with aldosterone-producing adenoma.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Asian People; Base Sequence; C

2015
Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism.
    Journal of hypertension, 2015, Volume: 33, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Animals; Case-Control Studies

2015
Diagnostic value of ACTH stimulation test in determining the subtypes of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotro

2015
PRKACA mutations in cortisol-producing adenomas and adrenal hyperplasia: a single-center study of 60 cases.
    European journal of endocrinology, 2015, Volume: 172, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocortical Adenoma; Ad

2015
Clinical risk factors of postoperative hyperkalemia after adrenalectomy in patients with aldosterone-producing adenoma.
    European journal of endocrinology, 2015, Volume: 172, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H

2015
Pre-B Lymphocyte Protein 3 (VPREB3) Expression in the Adrenal Cortex: Precedent for non-Immunological Roles in Normal and Neoplastic Human Tissues.
    Endocrine pathology, 2015, Volume: 26, Issue:2

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; G Protein-Coupled In

2015
Downregulation of miR-375 in aldosterone-producing adenomas promotes tumour cell growth via MTDH.
    Clinical endocrinology, 2015, Volume: 83, Issue:4

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Cell Adhesion Molecules; Cell Line,

2015
Circulating tissue inhibitor of matrix metalloproteinase-1 is associated with aldosterone-induced diastolic dysfunction.
    Journal of hypertension, 2015, Volume: 33, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diastole; Echoc

2015
Is there a role for segmental adrenal venous sampling and adrenal sparing surgery in patients with primary aldosteronism?
    European journal of endocrinology, 2015, Volume: 173, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Blood

2015
Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.
    Endocrine-related cancer, 2015, Volume: 22, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aged, 80 and over; Aldosterone; Bioma

2015
[Primary aldosteronism].
    La Revue du praticien, 2015, Volume: 65, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Algorithms; Antihypert

2015
Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone

2015
Pathogenesis of Adrenal Aldosterone-Producing Adenomas Carrying Mutations of the Na(+)/K(+)-ATPase.
    Endocrinology, 2015, Volume: 156, Issue:12

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocortical Carcinoma; Aldoster

2015
A Novel Somatic Deletion Mutation of ATP2B3 in Aldosterone-Producing Adenoma.
    Endocrine pathology, 2015, Volume: 26, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11

2015
A case of bilateral aldosterone-producing adenomas differentiated by segmental adrenal venous sampling for bilateral adrenal sparing surgery.
    Journal of human hypertension, 2016, Volume: 30, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Biomarkers, Tum

2016
Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism.
    Endocrine journal, 2016, Volume: 63, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Humans; Hyperaldosteronism; Ma

2016
Genotype-Specific Steroid Profiles Associated With Aldosterone-Producing Adenomas.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Chromatography, Liquid; DNA Mutationa

2016
Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Cytochrome P-450 CYP11B2; DNA;

2016
Adrenal Venous Sampling Is Useful for a Definitive Diagnosis in Cushing's Syndrome with Bilateral Adrenal Tumors.
    The Tokai journal of experimental and clinical medicine, 2015, Dec-20, Volume: 40, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; B

2015
GNAS mutations in adrenal aldosterone-producing adenomas.
    Endocrine journal, 2016, Volume: 63, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Chromogranins; Cohort St

2016
Aldosterone-producing adrenocortical carcinoma with prominent hepatic metastasis diagnosed by liver biopsy: a case report.
    BMC endocrine disorders, 2016, Jan-16, Volume: 16

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aged; Aldosterone; Biopsy; Female; Humans; Liver

2016
Genetics of Aldosterone-Producing Adenoma in Korean Patients.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Age Factors; Aldosterone; Calcium Channels,

2016
Activating mutations in CTNNB1 in aldosterone producing adenomas.
    Scientific reports, 2016, Jan-27, Volume: 6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; beta Catenin; Exons; Female; Humans;

2016
Adrenocortical cancer: mortality, hormone secretion, proliferation and urine steroids - experience from a single centre spanning three decades.
    BMC endocrine disorders, 2016, Mar-17, Volume: 16

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcino

2016
A Woman with Normotensive Primary Hyperaldosteronism.
    Acta medica Iranica, 2016, Volume: 54, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure;

2016
Genomic and proteomic analysis of the inhibition of synthesis and secretion of aldosterone hormone induced by quinocetone in NCI-H295R cells.
    Toxicology, 2016, 03-28, Volume: 350-352

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Apoptosis; Cell Line, Tumor; Dose-Response Re

2016
Double adrenocortical adenomas harboring independent KCNJ5 and PRKACA somatic mutations.
    European journal of endocrinology, 2016, Volume: 175, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cushing Syndrome; Cyclic AMP-Dependen

2016
Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation-Long-term Results and Recurrence Rate.
    Radiology, 2016, Volume: 281, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Biomarkers, Tumor; Catheter Ablation;

2016
Clinical Outcomes following Percutaneous Radiofrequency Ablation of Unilateral Aldosterone-Producing Adenoma: Comparison with Adrenalectomy.
    Journal of vascular and interventional radiology : JVIR, 2016, Volume: 27, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Bioma

2016
CACNA1H(M1549V) Mutant Calcium Channel Causes Autonomous Aldosterone Production in HAC15 Cells and Is Inhibited by Mibefradil.
    Endocrinology, 2016, Volume: 157, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Amino Acid Substitution; Calcium Ch

2016
PRKACA Somatic Mutations Are Rare Findings in Aldosterone-Producing Adenomas.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Amino Acid Substitution; Cells

2016
Expression of inflammation-related genes in aldosterone-producing adenomas with KCNJ5 mutation.
    Biochemical and biophysical research communications, 2016, 08-05, Volume: 476, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cytokines; Female; G Pro

2016
Comparison of radiofrequency ablation versus laparoscopic adrenalectomy for benign aldosterone-producing adenoma.
    La Radiologia medica, 2016, Volume: 121, Issue:10

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Catheter Ablation; Femal

2016
YPEL4 modulates HAC15 adrenal cell proliferation and is associated with tumor diameter.
    Molecular and cellular endocrinology, 2016, 10-15, Volume: 434

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Carrier Proteins; Cell L

2016
Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study.
    Endocrine pathology, 2017, Volume: 28, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aldosterone; Cushing Syndrome; Cytochrome

2017
Characteristics of Japanese aldosterone-producing adenomas with KCNJ5 mutations.
    Endocrine journal, 2017, Jan-30, Volume: 64, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; G Protein-Couple

2017
Long-term Results after CT-Guided Percutaneous Ethanol Ablation for the Treatment of Hyperfunctioning Adrenal Disorders.
    Clinics (Sao Paulo, Brazil), 2016, Oct-01, Volume: 71, Issue:10

    Topics: Ablation Techniques; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortica

2016
Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas.
    The Journal of clinical endocrinology and metabolism, 2017, Mar-01, Volume: 102, Issue:3

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Ad

2017
Aldosterone excess may inhibit insulin secretion: A comparative study on glucose metabolism pre- and post-adrenalectomy in patients with primary aldosteronism.
    Endocrine journal, 2017, Mar-31, Volume: 64, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Glucose;

2017
Optimization of left adrenal vein sampling in primary aldosteronism: Coping with asymmetrical cortisol secretion.
    Endocrine journal, 2017, Mar-31, Volume: 64, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Asymptomatic Diseases

2017
[Tetraparesis revealing Conn adenoma in a pregnant woman].
    The Pan African medical journal, 2016, Volume: 25

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure;

2016
A Late Diagnosis of Primary Aldosteronism.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2017, Volume: 24, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Antihypertensiv

2017
Accuracy of adrenal imaging and adrenal venous sampling in diagnosing unilateral primary aldosteronism.
    European journal of clinical investigation, 2017, Volume: 47, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged

2017
Primary aldosteronism and hypercortisolism due to bilateral functioning adrenocortical adenomas.
    Clinical and experimental nephrology, 2008, Volume: 12, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cushing Syndrome; Diagnosis, Differen

2008
Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2008, Volume: 9, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agents; Blood Pressu

2008
Development of an adrenocorticotropin-responsive human adrenocortical carcinoma cell line.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Cell Line, Tumor

2008
Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Cell Line, Tumor; Fluorescence; Gen

2008
Diagnosis of adrenocortical tumor in a neonate by detection of elevated blood 17-hydroxyprogesterone measured as a routine neonatal screening for congenital adrenal hyperplasia: a case report.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal Ins

2008
Coexistence of aldosterone-producing adrenocortical adenoma and pheochromocytoma in an ipsilateral adrenal gland.
    Endocrine journal, 2009, Volume: 56, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Al

2009
Regulation of aldosterone secretion by several aberrant receptors including for glucose-dependent insulinotropic peptide in a patient with an aldosteronoma.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Gastric

2009
Small tumor size as favorable prognostic factor after adrenalectomy in Conn's adenoma.
    European journal of endocrinology, 2009, Volume: 160, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Blood Pressure;

2009
Azelnidipine inhibits aldosterone synthesis and secretion in human adrenocortical cell line NCI-H295R.
    European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Angiotensin II; Azetidinecarboxylic

2009
Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma.
    Journal of the American Veterinary Medical Association, 2008, Oct-15, Volume: 233, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Fatal Outcome; Female; Ferre

2008
Primary aldosteronism with aldosterone-producing adenoma consisting of pure zona glomerulosa-type cells in a pregnant woman.
    Endocrine pathology, 2009,Spring, Volume: 20, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Estrogen Recept

2009
Factors determining cardiovascular and renal outcomes after adrenalectomy in patients with aldosterone-producing adrenal adenoma.
    The Tohoku journal of experimental medicine, 2009, Volume: 218, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cardiovas

2009
Aldosterone-producing adrenal cortical adenoma with oncocytic change and cytoplasmic eosinophilic globular inclusions.
    Endocrine pathology, 2009,Fall, Volume: 20, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Antihypertensive Agents; Female

2009
Increased ratio of mRNA expression of the genes CYP17 and CYP11B1 indicates autonomous cortisol production in adrenocortical tumors.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Adult;

2009
Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis.
    Cancer research, 2009, Jul-15, Volume: 69, Issue:14

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Blotting, Western; Bone Morphogenet

2009
Oxidative stress-related proteins in a Conn's adenoma tissue. Relevance for aldosterone's prooxidative and proinflammatory activity.
    Journal of endocrinological investigation, 2010, Volume: 33, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Female; Gene E

2010
Association of kidney function with residual hypertension after treatment of aldosterone-producing adenoma.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Creatinine; Fe

2009
[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:31-32

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diagnosis, Diff

2009
The dual role of the kidney in primary aldosteronism: key determinant in rescue from volume expansion and persistence of hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hyperten

2009
Isolation of human adrenocortical aldosterone-producing cells by a novel immunomagnetic beads method.
    Endocrinology, 2010, Volume: 151, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; CD56 Antigen; Humans; Immunohistochem

2010
An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis.
    Journal of pediatric endocrinology & metabolism : JPEM, 2009, Volume: 22, Issue:11

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldoste

2009
Aldosterone-producing adrenal adenoma and idiopathic intracranial hypertension--a pathogenetic link for aldosterone?
    QJM : monthly journal of the Association of Physicians, 2010, Volume: 103, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldostero

2010
Sporadic solitary aldosterone- and cortisol-co-secreting adenomas: endocrine, histological and genetic findings in a subtype of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Blotting, Western; Cytochrome P-450 C

2010
Licorice - or more?
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Glycyrrhiza;

2010
Salivary aldosterone as a diagnostic aid in primary aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:6

    Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aged, 80 and over; Aldos

2010
Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro.
    Cell and tissue research, 2010, Volume: 340, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocortical Carc

2010
Aldosterone-producing adenomas: mining for genes.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Genetic Predisposition to Disease; Genetic T

2010
Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Apoptosis; Biomarkers, T

2010
Case report: Coexistence of pheochromocytoma and bilateral aldosterone-producing adenomas in a 36-year-old woman.
    Journal of human hypertension, 2010, Volume: 24, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Femal

2010
[A 58-year-old hypertensive patient with primary hyperaldosteronism and renal artery stenosis].
    Medizinische Klinik (Munich, Germany : 1983), 2010, Volume: 105, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiography; Angioplasty, Balloon; Di

2010
Difficult-to-control hypertension due to bilateral aldosterone-producing adrenocortical microadenomas associated with a cortisol-producing adrenal macroadenoma.
    Journal of human hypertension, 2011, Volume: 25, Issue:2

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cushin

2011
Analysis of insulin sensitivity in adipose tissue of patients with primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:8

    Topics: Adiponectin; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldoster

2010
Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.
    Urology, 2010, Volume: 76, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; China; Cytochro

2010
Adrenal cortex remodeling and functional zona glomerulosa hyperplasia in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Fem

2010
Somatostatin receptor expression in adrenocortical tumors and effect of a new somatostatin analog SOM230 on hormone secretion in vitro and in ex vivo adrenal cells.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Apoptosis; Cell Cycle; Cell Prolifer

2011
Aldosterone producing adrenal adenomas are characterized by activation of calcium/calmodulin-dependent protein kinase (CaMK) dependent pathways.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2011, Volume: 43, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Base Sequence; Calcium-Calmodulin-Dep

2011
Medicine. The genetics of primary aldosteronism.
    Science (New York, N.Y.), 2011, Feb-11, Volume: 331, Issue:6018

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Animals; Disease Mode

2011
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension.
    Science (New York, N.Y.), 2011, Feb-11, Volume: 331, Issue:6018

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cell Line; Cell Proli

2011
[Primary hyperaldosteronism].
    Praxis, 2011, Mar-16, Volume: 100, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Aged; Aldosterone; Carcinoma; Di

2011
Cardiovascular changes in patients with primary aldosteronism after surgical or medical treatment.
    Journal of endocrinological investigation, 2012, Volume: 35, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aged; Aldosterone; Blood

2012
Insulin signaling in adipose tissue of patients with primary aldosteronism.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:2

    Topics: Adipocytes; Adipose Tissue; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult;

2011
The functional status of incidentally discovered bilateral adrenal lesions.
    Clinical endocrinology, 2011, Volume: 75, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hydr

2011
High prevalence of autonomous aldosterone secretion among patients with essential hypertension.
    European journal of clinical investigation, 2011, Volume: 41, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Blood Pressure; Case-Control St

2011
CD56 immunohistochemistry does not discriminate between cortisol-producing and aldosterone-producing adrenal cortical adenomas.
    Histopathology, 2011, Volume: 58, Issue:6

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Biomarkers, Tumor; CD56 Antigen; Dia

2011
[Flaccid paraplegia revealing an adenoma of Conn: a case report].
    Annales de cardiologie et d'angeiologie, 2012, Volume: 61, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Biomarkers; Fem

2012
Association of polymorphisms in angiotensin II receptor genes with aldosterone-producing adenoma.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2011, Volume: 31, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Case-Control Studies; China; Female; Humans;

2011
Significance of adrenocorticotropin stimulation test in the diagnosis of an aldosterone-producing adenoma.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Dexamethasone; Female;

2011
Clinical characteristics of primary hyperaldosteronism due to adrenal microadenoma.
    Steroids, 2011, Volume: 76, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Blood Pressure; Cytochrome P-450 CYP1

2011
The effect of treatment on monocyte and lymphocyte cytokine release in patients with aldosteronoma.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure;

2012
Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis.
    Endocrinology, 2012, Volume: 153, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Calcium; Calcium Channel Blockers;

2012
Pattern of adrenal hormonal secretion in patients with adrenal adenomas: the relevance of aldosterone in arterial hypertension.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenoco

2012
Morphological distinction of cortisol-producing and aldosterone-producing adrenal cortical adenomas: not only possible but a critical clinical responsibility.
    Histopathology, 2012, Volume: 60, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; CD56 Antigen; Humans; Hydrocortisone

2012
Visinin-like 1 is upregulated in aldosterone-producing adenomas with KCNJ5 mutations and protects from calcium-induced apoptosis.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Apoptosis; Calcium; Cell Line, Tumo

2012
Primary aldosteronism takes (KCNJ)five!
    Endocrinology, 2012, Volume: 153, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; G Protein-Coupled Inwardly-Rectifyi

2012
Polymorphic variation of CYP11B2 predicts postoperative resolution of hypertension in patients undergoing adrenalectomy for aldosterone-producing adenomas.
    International journal of urology : official journal of the Japanese Urological Association, 2012, Volume: 19, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11

2012
Aldosterone-producing adrenocortical carcinoma without hypertension.
    The Korean journal of internal medicine, 2012, Volume: 27, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosterone; Biopsy; Femal

2012
Hyperparathyroidism can be useful in the identification of primary aldosteronism due to aldosterone-producing adenoma.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Calcium; Comor

2012
Comprehensive re-sequencing of adrenal aldosterone producing lesions reveal three somatic mutations near the KCNJ5 potassium channel selectivity filter.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Base Sequenc

2012
KCNJ5 mutations in aldosterone- and cortisol-co-secreting adrenal adenomas.
    Endocrine journal, 2012, Volume: 59, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Dexamethasone; Female; G Protein-Coup

2012
A clinical prediction score to diagnose unilateral primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:10

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone;

2012
Characterization of NCI-H295R cells as an in vitro model of hyperaldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2013, Volume: 45, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Cell Adhesion; Cell Line, Tumor; Cy

2013
Elevation of angiotensin-II type-1-receptor autoantibodies titer in primary aldosteronism as a result of aldosterone-producing adenoma.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Autoantibodies; Autoimmunity; Diagnosis

2013
KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling.
    Molecular and cellular endocrinology, 2013, May-22, Volume: 371, Issue:1-2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cell Proliferation; Cytochrome P-450

2013
Dopaminergic modulation of aldosterone secretions on changes of sodium intake in aldosterone-producing adenoma.
    American journal of hypertension, 2002, Volume: 15, Issue:7 Pt 1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Diet, Sodium-R

2002
Thrombospondin expression in aldosterone-producing adenomas.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Female; Humans; Male; M

2002
Angiogenesis in human normal and pathologic adrenal cortex.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Antigens, CD34; Blood V

2002
Aldosterone-secreting adrenocortical carcinomas are associated with unique operative risks and outcomes.
    Surgery, 2002, Volume: 132, Issue:6

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Male; Middle Aged; R

2002
Conn's syndrome associated with Behcet's disease.
    Journal of Korean medical science, 2003, Volume: 18, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Behcet Syndrome; Female; Human

2003
Pathologic quiz case: a 57-year-old man with hypertension and hypokalemia.
    Archives of pathology & laboratory medicine, 2003, Volume: 127, Issue:4

    Topics: Adenocarcinoma, Clear Cell; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldoste

2003
Functional and nonfunctional adrenocortical tumors demonstrate a high responsiveness to low-dose adrenocorticotropin.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:5

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocorticotropic Hor

2003
Secretion of 6beta-hydroxycortisol by normal human adrenals and adrenocortical adenomas.
    Steroids, 2003, Volume: 68, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Dose-Response Re

2003
[Conns Syndrome].
    Nederlands tijdschrift voor geneeskunde, 1957, Jun-01, Volume: 101, Issue:22

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism

1957
Primary aldosteronism.
    The Quarterly journal of medicine, 1957, Volume: 26, Issue:103

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism

1957
A case of massive edema in association with an aldosterone-secreting adrenocortical adenoma.
    The American journal of medicine, 1958, Volume: 25, Issue:2

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Edema; Humans; Medica

1958
Conn's syndrome.
    Proceedings of the Royal Society of Medicine, 1958, Volume: 51, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism

1958
[Indications for surgery of adrenal cortex diseases].
    Medizinische Klinik, 1958, Oct-03, Volume: 53, Issue:40

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenogenital Syndrome; Aldostero

1958
[Hyperaldosteronism with adenomatous hyperplasia of the adrenals in a case of hypertension with refractory edema].
    Schweizerische medizinische Wochenschrift, 1959, Jan-24, Volume: 89, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Edema; Humans; Hyperaldostero

1959
Primary hyperaldosteronism and related hypertension. Surgical management.
    Archives of surgery (Chicago, Ill. : 1960), 1961, Volume: 82

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension

1961
Primary aldosteronism. The value of spironolactone in diagnosis.
    Lancet (London, England), 1961, Sep-16, Volume: 2, Issue:7203

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Lactones; Spirono

1961
Primary aldosteronism with severe hypertension relieved by adrenalectomy.
    The Medical journal of Australia, 1961, Aug-12, Volume: 48(2)

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hy

1961
Prominent peripheral edema associated with primary aldosteronism due to an adrenocortical adenoma.
    The Journal of clinical endocrinology and metabolism, 1960, Volume: 20

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Edema; Human

1960
Parallel biochemical and histochemical studies of an adrenocortical adenoma from a patient with primary aldosteronism.
    Acta endocrinologica, 1961, Volume: 38

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hype

1961
Primary aldosteronism.
    The Journal of urology, 1962, Volume: 88

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism

1962
[Conn's syndrome with adrenocortical adenoma. Action of spirolactone, SC-9420].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1962, Volume: 113

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diuretics; Humans; Hy

1962
Surgical treatment of hypertension -- primary aldosteronism. A review of 13 cases.
    The New England journal of medicine, 1962, 01-25, Volume: 266

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Essential Hypertension; Humans; Hyperaldoster

1962
[Primary hyperal-dosteronism. Clinical, biochemical and histochemical study in 2 cases].
    Revista medica de Chile, 1962, Volume: 90

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans

1962
Case records of the Massachusetts General Hospital. Case 44-1961.
    The New England journal of medicine, 1961, Jun-22, Volume: 264

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Hospitals, General; Humans; Massachu

1961
Primary hyperaldosteronism and renal disease. Report of a case and comments on differential diagnosis.
    Annales medicinae internae Fenniae, 1961, Volume: 50

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hyperaldoste

1961
Primary aldosteronism. Preoperative preparation with spironolactone.
    JAMA, 1962, Jun-23, Volume: 180

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid

1962
Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells.
    Endocrinology, 2004, Volume: 145, Issue:2

    Topics: Activins; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiot

2004
[Primary aldosteronism. A risk factor for aortic dissection?].
    Journal des maladies vasculaires, 2003, Volume: 28, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Aortic Aneurysm; Aortic Dissec

2003
Plasma aldosterone concentrations and plasma renin activity in healthy dogs and dogs with hyperadrenocorticism.
    The Veterinary record, 2003, Oct-25, Volume: 153, Issue:17

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; An

2003
Plasma cortisol and cortisone concentrations in normal subjects and patients with adrenocortical disorders.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adenoma; A

2004
Conn's syndrome (primary hyperaldosteronism) simulating polymyositis.
    Rheumatology international, 2005, Volume: 25, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diagnosis, Diff

2005
Primary hyperparathyroidism associatiated with aldosterone-producing adrenocortical adenoma and breast cancer: relation to MEN1 gene.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Breast Neoplasms; DNA

2004
Aldosterone regulation for 18 years in a case of primary aldosteronism.
    American journal of hypertension, 2004, Volume: 17, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Biomarkers; Calcium Channel Blockers; Humans; Hypera

2004
Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma.
    Hormone research, 2004, Volume: 62, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aldosterone; Diuretics; Female; Histocyto

2004
Serum interleukin-6 in patients with adrenal tumors.
    Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Case-Control S

2004
Retroperitoneal liposarcoma and aldosteronoma.
    Urology, 2004, Volume: 64, Issue:1

    Topics: Adipocytes; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Cell Differentiation; Humans; Lipo

2004
The expression of messenger RNA for ADP-ribosyl cyclase in aldosterone-producing adenomas.
    Clinical endocrinology, 2005, Volume: 62, Issue:4

    Topics: Adenoma; ADP-ribosyl Cyclase; Adrenal Cortex Neoplasms; Aldosterone; Angiotensins; Case-Control Stud

2005
Adrenocortical carcinoma producing 11-deoxycorticosterone: a rare cause of mineralocorticoid hypertension.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Catecholamines

2005
Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Angiotensin II; Cell Line, Tumor; D

2004
Inhibitory effects of digoxin and ouabain on aldosterone synthesis in human adrenocortical NCI-H295 cells.
    Journal of cellular physiology, 2005, Volume: 205, Issue:3

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Calcium Channel Blockers; Cell Line, Tumor; Cholesterol Side-

2005
Steroid profile in an adrenocortical carcinoma producing aldosterone.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2005, Volume: 113, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Middle Aged; Posture

2005
Corticosterone- and aldosterone-secreting adrenocortical tumor in a dog.
    Journal of the American Veterinary Medical Association, 2005, May-15, Volume: 226, Issue:10

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Animals; Antineoplastic Agents, Hormonal; Corticosterone; Dog

2005
Adrenocortical carcinoma with concomitant myelolipoma in a patient with hyperaldosteronism.
    Archives of pathology & laboratory medicine, 2005, Volume: 129, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosterone; Biomarkers, T

2005
Quiz page. Secondary hypertension with contralateral pheochromocytoma and aldosteronoma.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agent

2005
Expression profiles for steroidogenic enzymes in adrenocortical disease.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:9

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Aldosterone; Case-Control Studies; Compu

2005
Histopathological diagnosis and prognostic factors in adrenocortical carcinoma.
    Endocrine pathology, 2005,Spring, Volume: 16, Issue:1

    Topics: Adenoma, Oxyphilic; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aged, 80 and ov

2005
Primary aldosteronism combined with preclinical Cushing's syndrome in an elderly patient.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Aged, 80 and over; Aldosterone; Cushing Syn

2005
Expression profile of serotonin4 (5-HT4) receptors in adrenocortical aldosterone-producing adenomas.
    European journal of endocrinology, 2005, Volume: 153, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Gene Expression Profi

2005
Elevated expression of luteinizing hormone receptor in aldosterone-producing adenomas.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Corpus Luteum; DNA Primers; Female;

2006
Adrenocortical adenoma with rhabdoid features.
    Pathology, research and practice, 2006, Volume: 202, Issue:3

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Biomarkers

2006
Expression of telomerase (hTERT) in aldosterone-producing adrenocortical tumors.
    International journal of molecular medicine, 2006, Volume: 17, Issue:3

    Topics: Adrenal Cortex Neoplasms; Aged; Aldosterone; Anthropometry; Cell Nucleus; Gene Expression Regulation

2006
Long-term results of adrenalectomy in patients with aldosterone-producing adenomas: multivariate analysis of factors affecting unresolved hypertension and review of the literature.
    The American surgeon, 2005, Volume: 71, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H

2005
[Diagnosis and treatment outcome in primary aldosteronism based on a retrospective analysis of 187 cases].
    Orvosi hetilap, 2006, Jan-15, Volume: 147, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2

2006
Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumors.
    European journal of endocrinology, 2006, Volume: 154, Issue:4

    Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Female; Gen

2006
The role of adrenal venous sampling in the surgical management of primary aldosteronism.
    World journal of surgery, 2006, Volume: 30, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hype

2006
Unusual visualization of an adrenal carcinoma on NP-59 scintiscan.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2006, Volume: 105, Issue:4

    Topics: Adolescent; Adosterol; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Dehydroepian

2006
Adiponectin receptor expression in the human adrenal cortex and aldosterone-producing adenomas.
    International journal of molecular medicine, 2006, Volume: 17, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Base Sequence;

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
Clinics in diagnostic imaging (113).
    Singapore medical journal, 2007, Volume: 48, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Diagnosis, Differential; Femal

2007
[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore].
    Zhonghua yi xue za zhi, 2006, Nov-14, Volume: 86, Issue:42

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers, Tumor; Chymo

2006
Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Calcium; Cell Line, T

2007
Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Calcium; Cell Line, T

2007
Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Calcium; Cell Line, T

2007
Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Calcium; Cell Line, T

2007
Morning plasma aldosterone predicts the subtype of primary aldosteronism independent of sodium intake.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2007, Volume: 29, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers; Circadian Rh

2007
[Primary aldosteronism caused by aldosteronoma: problems in the etiologic diagnosis].
    Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Fem

2007
Tailored hormonal therapy in secretory adrenocortical cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang

2007
G-protein-coupled receptors in aldosterone-producing adenomas: a potential cause of hyperaldosteronism.
    The Journal of endocrinology, 2007, Volume: 195, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Base Sequence; Case-Control Studies;

2007
Heterogeneity of aldosterone-producing adenomas revealed by a whole transcriptome analysis.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Apoptosis; Calcium-Calmodulin-Dependent Protein Kina

2007
[Comparison of adrenal imaging and selective adrenal vein sampling in primary hyperaldosteronism].
    Deutsche medizinische Wochenschrift (1946), 2007, Volume: 132, Issue:46

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hydro

2007
D4 dopamine receptor enhances angiotensin II-stimulated aldosterone secretion through PKC-epsilon and calcium signaling.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 294, Issue:3

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Calcium; Cell Line, Tumor; Ce

2008
Primary aldosteronism due to unilateral adrenal microadenoma in an elderly patient: efficacy of selective adrenal venous sampling.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aged; Aldosterone; Humans; Hyperal

2008
Bilateral aldosterone-producing adenomas: differentiation from bilateral adrenal hyperplasia.
    QJM : monthly journal of the Association of Physicians, 2008, Volume: 101, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Case-Control Studies; F

2008
Adrenal venous sampling is absolutely requisite for definitively diagnosing primary aldosteronism as well as for detecting laterality of the adrenal lesion.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Blood S

2007
Localization of aldosterone-producing adrenocortical adenomas: significance of adrenal venous sampling.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Blood Spec

2007
[Complex study of the adrenal glands using angiography and radioimmunoassay of the hormone level in adrenal gland venous blood].
    Radiologia diagnostica, 1984, Volume: 25, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Cushing

1984
Endocrine characterization of the adrenal adenomas in a case of primary aldosteronism.
    The Tokai journal of experimental and clinical medicine, 1984, Volume: 9, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Cyclic

1984
[Malignant hypertension syndrome caused by aldosteroma-pheochromocytoma].
    Pediatriia, 1984, Issue:8

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hyperald

1984
Effect of N-terminal portion of pro-opiomelanocortin on aldosterone release by human adrenal adenoma in vitro.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals

1981
[Diagnosis and surgical treatment of adrenal cortical tumors].
    Klinicheskaia khirurgiia, 1982, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Androgens; Child; Diagnosis, Differenti

1982
Adrenal insufficiency secondary to carcinoma metastatic to the adrenal gland.
    Cancer, 1983, Oct-01, Volume: 52, Issue:7

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocort

1983
Effects of angiotensin II and ACTH on normal and tumourous human adrenocortical cells.
    Acta endocrinologica, 1983, Volume: 104, Issue:1

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone;

1983
[Diagnosis and treatment of adrenocortical tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:10

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angio

1983
Aging and aldosterone.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adult; Aged; Aging; Aldosterone; Blood Pressure; Diet

1983
Carcinoma of the adrenal cortex causing primary hyperaldosteronism. A case report and review of the literature.
    Cancer, 1983, Jun-15, Volume: 51, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiography; Carcinoma; Humans; Hydrocortisone; Hypera

1983
Adrenal cortical carcinoma: an unusual cause of hyperaldosteronism.
    Canadian Medical Association journal, 1983, Oct-01, Volume: 129, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Humans; Hyperaldosteronism; Hypertension; H

1983
Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism.
    Japanese heart journal, 1983, Volume: 24, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Aortic Dissection; Aortic Rupture; Female; Hu

1983
Hypertension caused by an aldosterone-secreting adenoma. Occurrence in a 7-year-old child.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Child; Female; Humans; Hyperaldosteronism; Renin; To

1984
Primary aldosteronism due to adrenal carcinomas.
    Klinische Wochenschrift, 1984, May-15, Volume: 62, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Combined Modality Therapy; Female; Foll

1984
[Localization of aldosteronoma by dynamic focusing ultrasonography].
    Zhonghua yi xue za zhi, 1983, Volume: 63, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Male; Middle Aged; Ultrasonography

1983
Real-time ultrasound of normal adrenal glands and small tumors.
    Journal of clinical ultrasound : JCU, 1984, Volume: 12, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital;

1984
[Ataractoanesthesia for removal of aldosterone producing tumor].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Fentanyl; Humans; Middle Aged; Neuroleptanal

1984
The diagnosis of primary hyperaldosteronism.
    Australian and New Zealand journal of medicine, 1984, Volume: 14, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Fludrocortisone; Glucocorti

1984
Surgical treatment of primary aldosteronism.
    Annales chirurgiae et gynaecologiae, 1983, Volume: 72, Issue:3

    Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hydrocortis

1983
Computed tomography and scintigraphy of aldosteronoma. A comparative study.
    Clinical nuclear medicine, 1983, Volume: 8, Issue:12

    Topics: 19-Iodocholesterol; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Evaluation Studies

1983
Solvent optimization of reversed-phase high-performance liquid chromatography for polar adrenal steroids using computer-predicted retentions.
    Journal of chromatography, 1984, Jan-13, Volume: 305, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Aldosterone; Chromatography, High Pressure Liquid

1984
[Radioimmunoassay for plasma aldosterone and its clinical application (author's transl)].
    Zhonghua yi xue za zhi, 1982, Volume: 62, Issue:3

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism;

1982
Clinical and biochemical features of patients with aldosterone-producing adenoma and idiopathic hyperaldosteronism.
    Klinische Wochenschrift, 1983, Jan-03, Volume: 61, Issue:1

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adenoma; Adrenal Cortex Neoplasms; Adult;

1983
Response of human aldosteronoma cells in culture to the N-terminal glycopeptide of pro-opiomelanocortin and gamma 3-MSH.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1983, Volume: 15, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Animals; Cells, Cultured; Female; Glycopeptides; Hum

1983
High plasma renin activities in primary aldosteronism with malignant hypertension. A case report.
    Japanese heart journal, 1980, Volume: 21, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension, Mal

1980
[Adrenal cortex transplantation. Animal experimental models for the human Cushing and Conn syndromes--clinical aspects of adrenal cortex transplantation].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1980, Volume: 51, Issue:10

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Animals; Corticosterone; Cushing Syndrome; Di

1980
Conn's syndrome in a patient with acromegaly.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1981, Volume: 13, Issue:3

    Topics: Acromegaly; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Female; Humans; Hyperten

1981
Primary aldosteronism associated with a primary double cancer of the thyroid and rectum: report of a case.
    Endocrinologia japonica, 1981, Volume: 28, Issue:6

    Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hyperten

1981
[Primary hyperaldosteronism: differentiation between aldosterone-producing adenoma and idiopathic adrenocortical hyperplasia (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1982, Jun-18, Volume: 107, Issue:24

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diet, Sodium-Restricted; Fema

1982
Characterisation of aldosterone metabolites cross reacting with aldosterone and tetrahydroaldosterone antibodies.
    Journal of steroid biochemistry, 1982, Volume: 17, Issue:2

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Antibodies; Antigen-Antibody Complex; Cross Reactions; Feces;

1982
An aldosterone-producing adrenal cortical adenoma.
    Anaesthesia, 1982, Volume: 37, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Anesthesia, General; Female; H

1982
Probable clonal origin of aldosteronomas versus multicellular origin of parathyroid "adenomas".
    Surgery, 1982, Volume: 92, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Genetic Linkage; Glucosephosphate Deh

1982
Hypermineralocorticism without excessive aldosterone secretion: an adrenal carcinoma producing deoxycorticosterone.
    Clinical endocrinology, 1982, Volume: 17, Issue:4

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Desoxycorticosterone; Female; Humans; Middle Aged

1982
[Diagnosis of aldosterone-secreting adenoma of the adrenal cortex].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Nov-15, Volume: 37, Issue:44

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Male; Middle Aged

1982
Primary aldosteronism caused by adrenal cortical carcinoma.
    Endocrinologia japonica, 1982, Volume: 29, Issue:6

    Topics: Adenoma; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Aldosterone; Glucocorticoids; Huma

1982
Spironolactone bodies in aldosteronomas and in the attached adrenals. Enzyme histochemical study of 19 cases of primary aldosteronism and a case of aldosteronism due to bilateral diffuse hyperplasia of the zona glomerulosa.
    The American journal of pathology, 1981, Volume: 103, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Animals; Female; Histocytochemistry; Humans;

1981
Adenylate cyclase of human aldosterone-producing adrenocortical adenoma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1981, Volume: 13, Issue:5

    Topics: Adenoma; Adenylyl Cyclases; Adrenal Cortex Neoplasms; Aldosterone; Humans

1981
[Diagnosis and therapy of hormonally active cancer of the adrenal cortex. Study of 5 cases].
    Schweizerische medizinische Wochenschrift, 1981, Jul-18, Volume: 111, Issue:29

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Aged; Aldosterone; Cushing Syndrom

1981
Hyperaldosteronism due to adrenocortical carcinoma 12 years after surgical removal of an aldosterone-producing adrenocortical adenoma.
    The Netherlands journal of medicine, 1981, Volume: 24, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Carcinoma; Female; Humans; Hyperaldosteronism; Middl

1981
[Anesthetic management of primary aldosteronism with extremely high plasma aldosterone level (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1981, Volume: 30, Issue:6

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Anesthesia; Female; Humans; Hyperaldosteronism; Middle Aged

1981
Deoxycorticosterone and aldosterone excretion in Cushing's syndrome.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Carcinoma;

1980
[Suppression of adrenal function by dexamethasone in radionuclide differential diagnosis of hyperaldosteronism].
    Meditsinskaia radiologiia, 1980, Volume: 25, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adult; Aldosterone; Depress

1980
[Studies on the mechanism of secretion of adrenal steroid hormones from adenomas of primary aldosteronism and Cushing's syndrome (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Jun-20, Volume: 56, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cushing Syndrome; Female; Humans; Hydrocortis

1980
[Preoperative diagnosis of the localization of primary aldosteronoma (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Oct-20, Volume: 56, Issue:10

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hydrocortison

1980
Gene expression of angiotensin II receptor in blood cells of Cushing's syndrome.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone;

1995
[Hyperaldosteronism sensitive to dexamethasone with adrenal adenoma. Clinical, biological and genetic study].
    Presse medicale (Paris, France : 1983), 1995, Sep-23, Volume: 24, Issue:27

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Dexamethasone; Fem

1995
Long-PCR of the ANP gene and PCR-SSCP analysis of the proximal promoter region of the ANP gene in patients with aldosterone producing adenoma.
    Biochemical and biophysical research communications, 1995, Oct-04, Volume: 215, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Atrial Natriuretic Factor; Base Sequence; Deoxyribon

1995
21-Deoxyaldosteronism is not a new syndrome.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:11

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Syndrome

1995
Renal and adrenal sparing surgery for patients with primary aldosteronism and primary reninoma.
    The Journal of urology, 1995, Volume: 153, Issue:6

    Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans

1995
Therapeutic outcome of primary aldosteronism: adrenalectomy versus enucleation of aldosterone-producing adenoma.
    The Journal of urology, 1995, Volume: 153, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Angiotensin II;

1995
Exaggerated blood pressure response to angiotensin II in patients with Cushing's syndrome due to adrenocortical adenoma.
    European journal of endocrinology, 1994, Volume: 131, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cu

1994
Percutaneous computed tomography-guided ethanol injection in aldosterone-producing adrenocortical adenoma.
    European journal of endocrinology, 1995, Volume: 132, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Ethanol; Humans; Injections, I

1995
Postural stimulation test in patients with aldosterone producing adenomas.
    Clinical endocrinology, 1994, Volume: 41, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hydrocortisone; Hyperal

1994
Different lipid contents between aldosterone-producing and nonhyperfunctioning adrenocortical adenomas: in vivo measurement using chemical-shift magnetic resonance imaging.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Lipid Metabolism; Magne

1994
Plasma 18-oxocortisol levels in the patients with adrenocortical disorders.
    Clinical endocrinology, 1994, Volume: 40, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cushing Syndrome; Female; Humans; Hydrocortis

1994
Primary hyperaldosteronism.
    The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Cushing Syndrome; Diagnosis, Differential; Female; H

1993
Angiotensin increases aldosterone synthase mRNA levels in human NCI-H295 cells.
    Molecular and cellular endocrinology, 1993, Volume: 94, Issue:2

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Colforsin; Cytochrome P-450 CYP11B2; Cytochro

1993
Detection of renin mRNA in aldosterone-producing adenomas by polymerase chain reaction.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Base Sequence; Elect

1993
Angiotensin-responsive aldosterone-producing adenomas: postoperative disappearance of aldosterone response to angiotensin.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Angiotensin II; Femal

1993
Primary aldosteronism in a patient with an aldosterone-producing adenoma.
    Clinical chemistry, 1993, Volume: 39, Issue:8

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Humans; Hyperaldosteronism; Ma

1993
Expression of steroidogenic enzyme messenger ribonucleic acids and corticosteroid production in aldosterone-producing and "nonfunctioning" adrenal adenomas.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:3

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenodoxin; Aldosterone; Cholesterol Si

1993
Cortisol production by aldosterone-producing adenomas in vitro.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiote

1993
Human NCI-H295 adrenocortical carcinoma cells: a model for angiotensin-II-responsive aldosterone secretion.
    Endocrinology, 1993, Volume: 133, Issue:4

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Calcium; Carcinoma; Cytochrome P-450 CYP11B2;

1993
Reduced response to metoclopramide and anomalous rising response to upright posture of plasma aldosterone concentration in Japanese patients with aldosterone-producing adenoma.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Chromatography

1993
[A rare case of primary aldosteronism due to bilateral functioning adrenocortical adenomas].
    Nihon Naibunpi Gakkai zasshi, 1993, Mar-20, Volume: 69, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diabetes Mellitus; Humans; Hyperaldosteronism

1993
The unique steroidogenesis of the aldosteronoma in the differential diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Corticosterone; Diagnosis, Differential; Female; Hum

1993
Significance of steroidogenic enzymes in the pathogenesis of adrenal tumour.
    Acta endocrinologica, 1993, Volume: 128, Issue:3

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Cush

1993
Unilateral diffuse adrenal hyperplasia masquerading as aldosterone-producing adenoma in primary hyperaldosteronism.
    Urologia internationalis, 1993, Volume: 50, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism;

1993
Combined Conn's and Cushing's syndrome: an unusual presentation of adrenal adenoma.
    Acta clinica Belgica, 1995, Volume: 50, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cushing Syndrome; Female; Humans; Hyd

1995
Alterations of calcium metabolism and of parathyroid function in primary aldosteronism, and their reversal by spironolactone or by surgical removal of aldosterone-producing adenomas.
    American journal of hypertension, 1995, Volume: 8, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Analysis

1995
Characteristics of aldosterone-producing adenoma responsive to upright posture.
    Endocrine journal, 1995, Volume: 42, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Diuretics; Female; Furosemide;

1995
[Dysfunction of the aldosterone synthesis pathway as a marker of malignity in symptomatic and asymptomatic adrenal masses].
    Bulletin de l'Academie nationale de medecine, 1995, Volume: 179, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone;

1995
Primary aldosteronism.
    Endocrinology and metabolism clinics of North America, 1995, Volume: 24, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldost

1995
Hyperaldosteronism: sampling the adrenal veins.
    Radiology, 1996, Volume: 198, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldos

1996
Adrenal androgen biosynthesis with special attention to P450c17.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Aldehyde-Lyases; Aldosterone; Base Sequen

1995
Differentiation of adrenal adenomas from nonadenomas using CT attenuation values.
    AJR. American journal of roentgenology, 1996, Volume: 166, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aged; Age

1996
Low dehydroepiandrosterone sulfate (DHEA-S) level is not a good predictor of hormonal activity in nonselected patients with incidentally detected adrenal tumors.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and ov

1996
Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients.
    Archives of internal medicine, 1996, Jun-10, Volume: 156, Issue:11

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism;

1996
[Evaluation of surgical treatment for patients with multiple aldosteronoma: analysis of 11 cases].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1995, Volume: 33, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Diagnosis, Differential; Femal

1995
The H295R human adrenocortical cell line contains functional atrial natriuretic peptide receptors that inhibit aldosterone biosynthesis.
    Molecular and cellular endocrinology, 1996, Apr-19, Volume: 118, Issue:1-2

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Atrial Natriuretic Factor; Biological Assay;

1996
Ultrastructural dynamics of mitochondrial morphology in varying functional forms of human adrenal cortical adenoma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1996, Volume: 28, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Endoplasmic Reticulum; Female; Humans;

1996
Ectopic aldosteronoma associated to another adrenocortical adenoma in the adrenal gland of the same side.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:10

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Paraneoplastic Endocrine Synd

1995
p53 mutations in adrenal tumors: Caucasian patients do not show the exon 4 "hot spot" found in Taiwan.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Ca

1996
[Adrenal cortex adenoma in Conn syndrome].
    Rontgenpraxis; Zeitschrift fur radiologische Technik, 1996, Volume: 49, Issue:7

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Diagnostic Ima

1996
Magnetic resonance imaging of adrenocortical adenomas in childhood: correlation with computed tomography and ultrasound.
    Pediatric radiology, 1996, Volume: 26, Issue:11

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hor

1996
Altered 11 beta-hydroxylase activity in glucocorticoid-suppressible hyperaldosteronism.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Corticosterone; Cortodoxone; Desoxycorticosterone; Glucocorti

1996
Effects of taxol on the human NCI-H295 adrenocortical carcinoma cell line.
    Endocrine research, 1996, Volume: 22, Issue:4

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Apoptosis; Cell Survival; Culture Media, Conditioned; Dehydro

1996
Comparative effect of pituitary adenylate cyclase-activating polypeptide on aldosterone secretion in normal bovine and human tumorous adrenal cells.
    Endocrinology, 1997, Volume: 138, Issue:2

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured;

1997
Scintigraphic assessment of therapeutic success in aldosteronomas treated by transcatheter arterial embolization using absolute ethanol.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:2

    Topics: Adosterol; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Chemoembolization,

1997
Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery.
    European journal of endocrinology, 1997, Volume: 136, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Medulla;

1997
Double adenomas with different pathological and hormonal features in the left adrenal gland of a patient with Cushing's syndrome.
    Clinical endocrinology, 1997, Volume: 46, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Culture Techniques; Cushing Syndrome; Cytochrome P-4

1997
Aldosterone-producing adrenocortical carcinoma metastases found seven years after adrenalectomy.
    International journal of urology : official journal of the Japanese Urological Association, 1997, Volume: 4, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Carcinoma; Combined Modality Therapy; Female;

1997
An ominously low potassium level.
    Medicine and health, Rhode Island, 1997, Volume: 80, Issue:9

    Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypokalemia; Male

1997
Malignant hypertension in a patient with primary aldosteronism with elevated active renin concentration.
    Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Antihypertensiv

1997
[Immunohistochemical study of endothelin-1 in adrenal tumors].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1996, Volume: 18, Issue:5

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aged;

1996
Incidentally discovered adrenal tumors: endocrine and scintigraphic correlates.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; 3-Iodobenzylguanidine; Adenoma; Adolescent; Adrenal Cortex Neoplasms;

1998
Aldosterone-producing adrenal cortical cancer: a case report and analysis of steroidogenic enzymes in the tumor.
    Endocrine journal, 1997, Volume: 44, Issue:4

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Cytochrome P-450 Enzyme System; Humans; Hydrocortisone; Male;

1997
The analysis of steroidogenic activity in non-hyperfunctioning adrenocortical adenoma.
    Endocrine journal, 1997, Volume: 44, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aldoste

1997
ACTH-induced cortisol secretion is mediated by cAMP and PKC in various adrenocortical adenomas.
    Endocrine journal, 1997, Volume: 44, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensi

1997
Adrenalectomy for primary aldosteronism: long-term follow-up study in 29 patients.
    World journal of surgery, 1998, Volume: 22, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Diagnosis

1998
Telomerase activity in adrenal cortical tumors and pheochromocytomas with reference to clinicopathologic features.
    Urological research, 1998, Volume: 26, Issue:1

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Hum

1998
Localization and expression of adrenocorticotropic hormone receptor mRNA in normal and neoplastic human adrenal cortex.
    The Journal of endocrinology, 1998, Volume: 156, Issue:3

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Blotting, Northern; Car

1998
Retroperitoneoscopic partial adrenalectomy for aldosterone-producing adenoma using an ultrasonically activated scalpel.
    British journal of urology, 1998, Volume: 82, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans;

1998
[Primary hyperaldosteronism and adenoma of the adrenal cortex. Suppression of aldosterone with dexamethasone].
    Annales d'endocrinologie, 1998, Volume: 59, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Cortisone; Dexamethasone; Hormones; Humans; Hyperald

1998
Gene expression and roles of angiotensin II type 1 and type 2 receptors in human adrenals.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1998, Volume: 30, Issue:8

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Blotting, S

1998
Aminoglutethimide suppresses adrenocorticotropin receptor expression in the NCI-h295 adrenocortical tumor cell line.
    The Journal of endocrinology, 1998, Volume: 159, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Analysis of V

1998
Human adrenocortical NCI-H295 cells express VIP receptors. Steroidogenic effect of vasoactive intestinal peptide (VIP).
    Peptides, 1998, Volume: 19, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Aldosterone; Dehydroepiandrostero

1998
High and non-suppressible plasma renin activity in a patient with aldosterone producing adenoma: pathophysiologic and diagnostic implications.
    Journal of human hypertension, 1999, Volume: 13, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Renin

1999
p53 protein and its messenger ribonucleic acid in human adrenal tumors.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Blotting, Northern; Cushing

1998
Primary aldosteronism with aldosterone-producing adrenal adenoma in a pregnant woman.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Cesarean Sectio

1999
Adrenal cancer with hypertension but low plasma renin and aldosterone.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Female; Humans; Hypertension; Renin

1999
Ventricular fibrillation: an extreme presentation of primary hyperaldosteronism.
    The Canadian journal of cardiology, 1999, Volume: 15, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Death, Sudden,

1999
Evidence for a potential role for HDL as an important source of cholesterol in human adrenocortical tumors via the CLA-1 pathway.
    Endocrine journal, 1999, Volume: 46, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocor

1999
[Woman with refractory hypertension and hypokalemia].
    Revista clinica espanola, 1999, Volume: 199, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adrenocorticotrop

1999
Mutations in CYP11B1 gene converting 11beta-hydroxylase into an aldosterone-producing enzyme are not present in aldosterone-producing adenomas.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Base Sequence; Blotting, Southern; Cytochrome

1999
[Case of primary aldosteronism caused by adrenal microadenoma that permitted clinical observation from onset].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Dec-10, Volume: 88, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Female; Hormones, Ectopic; Huma

1999
Recurrence of adrenal aldosterone-producing adenoma.
    Postgraduate medical journal, 2000, Volume: 76, Issue:893

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Female; Humans; Middle Aged; Neoplasm

2000
Multiple endocrine neoplasia type 1 gene expression is normal in sporadic adrenocortical tumors.
    European journal of endocrinology, 2000, Volume: 142, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Carcinoma; Gene Expression; Humans;

2000
Primary aldosteronism in a patient with familial adenomatous polyposis.
    Mayo Clinic proceedings, 2000, Volume: 75, Issue:6

    Topics: Adenomatous Polyposis Coli; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldos

2000
Outcome in patients with adrenal incidentaloma selected for surgery: an analysis of 88 cases investigated in a single clinical center.
    European journal of endocrinology, 2000, Volume: 143, Issue:1

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and ov

2000
Adrenal incidentalomas showing unilateral concordant visualization by adrenocortical scintigraphy: comparison with adenomas in Cushing's syndrome.
    Annals of nuclear medicine, 2000, Volume: 14, Issue:3

    Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adu

2000
CT-Guided acetic acid injection therapy for aldosterone-producing adrenocortical adenoma: a preliminary report of three cases.
    Endocrine journal, 2000, Volume: 47, Issue:2

    Topics: Acetic Acid; Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Blood Pressure; Ethanol; Female;

2000
Endothelin-1 stimulates aldosterone synthesis in Conn's adenomas via both A and B receptors coupled with the protein kinase C- and cyclooxygenase-dependent signaling pathways.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2000, Volume: 48, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone;

2000
Biosynthesis and metabolism of steroid hormones by human adrenal carcinomas.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2000, Volume: 33, Issue:10

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Buclade

2000
Computerized-tomography-guided percutaneous tumor ablation using acetic acid injection in an aldosterone-producing tumor--a novel therapy.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 2000, Volume: 63, Issue:11

    Topics: Acetic Acid; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Injections, Intralesional; Middl

2000
Hyperaldosteronism in a cat with metastasised adrenocortical tumour.
    The veterinary quarterly, 2001, Volume: 23, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Animals; Carcinoma; Cat Diseases; Cats; Const

2001
Angiotensin II type 1 receptor and ACTH receptor expression in human adrenocortical neoplasms.
    Clinical endocrinology, 2001, Volume: 54, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Autoradiography; Blotting,

2001
A case of aldosterone-producing adrenocortical adenoma associated with preclinical Cushing's syndrome and hypersecretion of parathyroid hormone.
    Endocrine journal, 2001, Volume: 48, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Calcium;

2001
Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome).
    Clinical endocrinology, 2001, Volume: 54, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Case-Control Studies; Chi-Square Distri

2001
[Renovascular hypertension coexisting with an aldosteronoma].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2001, Jun-10, Volume: 90, Issue:6

    Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hyp

2001
In vitro release of aldosterone and cortisol in human adrenal adenomas correlates to mRNA expression of steroidogenic enzymes for genes CYP11B2 and CYP17.
    World journal of surgery, 2001, Volume: 25, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cushing Syndrome; Cytoch

2001
Localization of the endothelin system in aldosterone-producing adenomas.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Aspartic Acid Endopep

2001
Expression and function of adrenomedullin and its receptors in Conn's adenoma cells.
    International journal of molecular medicine, 2001, Volume: 8, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenomedullin; Aldosterone; Angiotensin II; Gene Expression Regu

2001
[Aldosterone and cortisol-producing adrenal tumor].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2001, Nov-10, Volume: 90, Issue:11

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hydrocortisone; Middle Aged

2001
Test and teach. Surgically correctable hypertension. Conn's syndrome and spironolactone bodies.
    Pathology, 2001, Volume: 33, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertens

2001
Hypertension due to a giant aldosterone-secreting adenoma.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hypertension; Middle Aged; Tomograph

2001
Unique cases of unilateral hyperaldosteronemia due to multiple adrenocortical micronodules, which can only be detected by selective adrenal venous sampling.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:3

    Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Aldostero

2002
Morphometric analysis, at electron microscope level, combined with hormone assay of nonfunctioning adrenocortical adenomas: comparison with aldosterone-producing adenomas.
    Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan, 2001, Volume: 34, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Hormones

2001
Apoptosis control and proliferation marker in human normal and neoplastic adrenocortical tissues.
    British journal of cancer, 2002, May-20, Volume: 86, Issue:10

    Topics: Adenocarcinoma; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Antigen

2002
Primary aldosteronism. A study in contrasts.
    The American journal of medicine, 1975, Volume: 59, Issue:3

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy;

1975
[In vivo and in vitro studies on steroid production by aldosteronoma (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1978, Mar-20, Volume: 54, Issue:3

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenoco

1978
Primary aldosteronism: inability to differentiate unilateral from bilateral adrenal lesions by various routine clinical and laboratory data and by peripheral plasma aldosterone.
    Acta endocrinologica, 1978, Volume: 89, Issue:4

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone;

1978
ACTH-dependent aldosterone excess due to adrenocortical adenoma: a variant of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensi

1978
[Primary hyperaldosteronism syndrome].
    Minerva medica, 1979, Jun-08, Volume: 70, Issue:27

    Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone

1979
Cushing's syndrome due to adrenocortical carcinoma - a comphrensive clinical and biochemical study of patients treated by surgery and chemotherapy.
    Acta endocrinologica, 1979, Volume: 91, Issue:2

    Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Carcinoma; Cort

1979
Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldost

1978
Hyperaldosteronism with coexistence of adrenal cortical adenoma and pheochromocytoma.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1979, Volume: 78, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hydrocortisone; Hyp

1979
Aldosterone producing adenoma: fludrocortisone suppression and left adrenal vein catheterisation in definitive diagnosis and management.
    Australian and New Zealand journal of medicine, 1979, Volume: 9, Issue:6

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Catheteriza

1979
Concurrent hypersecretion of aldosterone and cortisol from the adrenal cortical adenoma.
    The American journal of medicine, 1979, Volume: 67, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hydrocortisone

1979
Hypertension and aldosterone overproduction without renin suppression in Cushing's syndrome from an adrenal adenoma.
    The American journal of medicine, 1979, Volume: 67, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Corticosterone; Cushing Syndrome; Desoxycorti

1979
[Plasma aldosterone and electrolytes in primary and secondard aldosteronism (author's transl)].
    Medizinische Klinik, 1979, Sep-14, Volume: 74, Issue:37

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Ascites; Electrolytes; Female; Humans; Hypera

1979
[Blood aldosterone level under the effect of posture change in patients with primary hyperaldosteronism].
    Polskie Archiwum Medycyny Wewnetrznej, 1979, Volume: 62, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hype

1979
[Androgen secreting adrenal cortex tumors].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Oct-15, Volume: 34, Issue:20

    Topics: Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Androgens; Estrogens; Female; Humans; Hydrocorti

1979
[Case of disappearance of skin papillomas and gastric polyp after removal of corticosteroma].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Glucocorticoids; Huma

1978
[A case report of primary adolsteronism caused by bilateral adrenal aldosteronomas (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hype

1978
[Difficulties of clinical diagnosis of Conn's disease and topical diagnosis of aldosteromas].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:5

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aldosterone; Diagnosis, Differ

1978
Histochemical investigation of aldosterone-secreting cells adenoma of the adrenal cortex.
    Endokrinologie, 1978, Volume: 72, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Histocytochemistry; Humans; Microscopy, Electron

1978
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-1977.
    The New England journal of medicine, 1977, Apr-28, Volume: 296, Issue:17

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aged; Aldosterone; Femal

1977
Concurrent hypercortisolism and hypermineralocorticoidism.
    The American journal of medicine, 1977, Volume: 62, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Cushing Syndrome; Desoxycorticosterone; Humans; Hydr

1977
[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism].
    La Nouvelle presse medicale, 1977, Sep-10, Volume: 6, Issue:29

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone; Blo

1977
Spironolactone-induced inhibition of aldosterone biosynthesis in primary aldosteronism: morphological and functional studies.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:12

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism;

1977
[Diagnosis of primary hyperaldosteronism. Diagnostic means for hospital and private practice].
    Fortschritte der Medizin, 1976, Jun-17, Volume: 94, Issue:18

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Family Practice; Female; Hosp

1976
A perspective on aldosterone abnormalities.
    Clinical endocrinology, 1976, Volume: 5, Issue:4

    Topics: Addison Disease; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Hy

1976
The dexamethasone-modified adrenal scintiscan in hyporeninemic aldosteronism (tumor versus hyperplasia). A comparison with adrenal venography and adrenal venous aldosterone.
    The Journal of laboratory and clinical medicine, 1976, Volume: 88, Issue:5

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; D

1976
[Neoplasms of the zona glomerulosa of the adrenal cortex].
    Nihon rinsho. Japanese journal of clinical medicine, 1976, Oct-10, Volume: 34, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone;

1976
[Enflurance anesthesia in primary aldosteronism, with special reference to its effects on serum aldosterone levels].
    Masui. The Japanese journal of anesthesiology, 1976, Volume: 25, Issue:13

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Anesthesia, Endotracheal; Enflurane; Female;

1976
Proceedings: Steroid production rates in two patients with corticosterone-producing adenomata.
    The Journal of endocrinology, 1975, Volume: 65, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Female; Hum

1975
Selective hypoaldosteronism despite prolonged pre- and postoperative hyperreninemia in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Paraneoplastic Endo

1975
Selection of patients and operative approach in primary aldosteronism.
    Annals of surgery, 1975, Volume: 182, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands;

1975
[Proceedings: Normal values and samples of findings in diseases of the hypophysis and the adrenal cortex].
    Medizinische Klinik, 1975, Jun-06, Volume: 70, Issue:23

    Topics: Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Hyperplasia, Cong

1975
[Primary aldosteronism: diagnosis, laterality and regulation of hormone secretion].
    Schweizerische medizinische Wochenschrift, 1975, Dec-13, Volume: 105, Issue:50

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Female; Functional Laterali

1975
[Physiopathology and clinical aspects of primary hyperaldosteronism].
    Recenti progressi in medicina, 1975, Volume: 59, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Proteinuri

1975
[Primary aldosteronism].
    Schweizerische medizinische Wochenschrift, 1976, Apr-03, Volume: 106, Issue:14

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Aldosterone; Antihyp

1976
Clinical and genetic features of adrenocortical lesions in multiple endocrine neoplasia type 1.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:1

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Chr

1992
Disordered expression of adrenal steroidogenic P450 mRNAs in incidentally discovered nonfunctioning adrenal adenoma.
    Endocrinologia japonica, 1992, Volume: 39, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aged; Aldosterone; Blotting, Northern; Cytochrome P-450 Enzyme Sy

1992
Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism.
    Journal of endocrinological investigation, 1992, Volume: 15, Issue:1

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis,

1992
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1992. A 52-year-old man with hypertension, hypokalemia, and an adrenal mass.
    The New England journal of medicine, 1992, Jun-11, Volume: 326, Issue:24

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemi

1992
Local renin-angiotensin system in human adrenals and aldosteronomas.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:6 Pt 2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; A

1992
Decreased binding capacity for alpha-human atrial natriuretic peptide in aldosterone-producing adrenocortical adenoma.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1991, Volume: 82, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Atrial Natriuretic Factor; Binding Sites; Humans; Re

1991
Diagnostic approach to patients with primary hyperaldosteronism.
    Acta clinica Belgica, 1991, Volume: 46, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertens

1991
Aldosterone-producing adenoma--variable serum aldosterone response to postural change: a case report.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1991, Volume: 48, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Posture

1991
Basal and ACTH-stimulated cortisol and aldosterone release from adrenocortical adenomas in vitro.
    The European journal of surgery = Acta chirurgica, 1991, Volume: 157, Issue:3

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldoste

1991
Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:12

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southe

1991
Diagnosis of primary hyperaldosteronism: importance of correlating CT findings with endocrinologic studies.
    AJR. American journal of roentgenology, 1992, Volume: 158, Issue:3

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosteron

1992
The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Animal

1991
[Aldosteroma (Conn's syndrome)].
    Kardiologiia, 1991, Volume: 31, Issue:12

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Fema

1991
Expression of cytochrome P-450 mRNAs in steroidogenesis of adrenocortical adenomas from patients with primary aldosteronism.
    Molecular and cellular endocrinology, 1991, Volume: 76, Issue:1-3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Blotting, Northern; Cytochrome P-450 En

1991
[Establishment of human adrenal gland and aldosterone-producing adenoma culture and the effect of alpha-human atrial natriuretic factor on aldosterone secretion in vitro].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1991, Volume: 13, Issue:3

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Atrial Natriuretic Factor; Cu

1991
In vitro responsiveness of aldosterone-producing adenoma to angiotensin II, K and ACTH.
    Endocrinologia japonica, 1990, Volume: 37, Issue:4

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone;

1990
New aspects of mineralocorticoid hypertension.
    Hormone research, 1990, Volume: 34, Issue:3-4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Atrial Natri

1990
An antioxidant drug, silibinin, modulates steroid secretion in human pathological adrenocortical cells.
    The Journal of endocrinology, 1990, Volume: 124, Issue:2

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex; Adrenal Cortex Diseases; Adrenal Cortex Hormones;

1990
High-renin malignant hypertension secondary to an aldosterone-producing adenoma.
    Nephron, 1990, Volume: 54, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension, Malignant; Reni

1990
[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension].
    Kardiologiia, 1990, Volume: 30, Issue:7

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Atrophy; Desoxycorticosterone; Humans; Hypera

1990
Feminizing adrenocortical tumor: steroid hormone response to ketoconazole.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:2

    Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Aldosterone; Androgen-Insensitivity Syndrome; Corticoster

1990
Conn's syndrome with rhabdomyolysis mimicking deep vein thrombophlebitis.
    Southern medical journal, 1990, Volume: 83, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hype

1990
[Effects of surgical treatment on circadian variations of arterial pressure in patients with primary aldosteronism and renovascular hypertension].
    Kardiologiia, 1990, Volume: 30, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Blood Pressure Determin

1990
Iodomethylnorcholesterol uptake in an aldosteronoma shown by dexamethasone-suppression scintigraphy: relationship to adenoma size and functional activity.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:4

    Topics: Adenoma; Adosterol; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Cholesterol; Dexame

1990
Idiopathic aldosteronism masquerading as discrete aldosterone-secreting adrenal cortical neoplasms among patients with primary aldosteronism.
    Surgery, 1989, Volume: 106, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Diagnos

1989
[Crisis of arterial hypertension in patients with primary aldosteronism].
    Kardiologiia, 1989, Volume: 29, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone;

1989
Hyperfunctioning and nonhyperfunctioning benign adrenal cortical lesions: characterization and comparison with MR imaging.
    Radiology, 1989, Volume: 171, Issue:3

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone;

1989
Immunohistochemical demonstration of cholesterol side-chain cleavage cytochrome P-450 in bovine and human adrenals.
    Pathology, research and practice, 1989, Volume: 184, Issue:3

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Animals; Cattle; Cus

1989
[Clinico-morphologic characteristics of 2 tumor forms of primary hyperaldosteronism].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hyperpla

1989
Angiotensin-responsive aldosterone-producing adenoma masquerades as idiopathic hyperaldosteronism (IHA: adrenal hyperplasia) or low-renin essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Dexamet

1987
Lack of atrial natriuretic peptide receptors in human aldosteronoma.
    Biochemical and biophysical research communications, 1988, Apr-15, Volume: 152, Issue:1

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Atrial

1988
Lack of inhibitory effect of alpha-human atrial natriuretic polypeptide on cortisol secretion in cultured adrenocortical adenoma cells from the patients with Cushing's syndrome.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Atrial Natriuretic Factor; Ce

1988
[Clinical use of magnetic resonance tomography for assessing adrenal function in patients with arterial hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1988, Volume: 11, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Diagnosis, Di

1988
Immunohistochemical study of cytochrome P-45017 alpha in human adrenocortical disorders.
    Human pathology, 1989, Volume: 20, Issue:2

    Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Animals; Ca

1989
Atrial natriuretic peptide levels during angiotensin infusion and indomethacin administration are consistent with angiotensin-mediated regulation in man.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Atrial Natriureti

1987
Plasma beta-endorphin levels in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:2

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Age

1985
Effects of proopiomelanocortin peptides and angiotensin II on steroidogenesis in isolated aldosteronoma cells.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:3

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone

1985
Central serotonergic stimulation of aldosterone secretion.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:4

    Topics: 5-Hydroxytryptophan; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone;

1985
Non-functioning adrenocortical adenoma in culture. Quantitative and morphological observations.
    Acta pathologica japonica, 1985, Volume: 35, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aged; Aldosterone; Angiotensin II; C

1985
[Morphological characteristics of aldosteronoma].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1985, Volume: 14, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Inclusion

1985
Diagnosis and pathophysiology of Cushing's syndrome.
    Comprehensive therapy, 1986, Volume: 12, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Cushing Syndrome; Femal

1986
Lack of inhibitory effect of alpha-human atrial natriuretic polypeptide on aldosteronogenesis in aldosterone-producing adenoma.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Atrial Natriuretic Factor; Autoradiography; C

1986
Adrenocortical adenoma with primary aldosteronism in culture.
    Acta pathologica japonica, 1986, Volume: 36, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone; Cells, Cultured;

1986
[A 54-year-old patient with muscle weakness, hypokalemia and arterial hypertension].
    Der Internist, 1988, Volume: 29, Issue:10

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Middle Ag

1988
[Radioimmunoassay of aldosterone in saliva and its preliminary clinical use].
    Zhonghua yi xue za zhi, 1986, Volume: 66, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hyperaldosteronism;

1986
[Malignant adrenal cortex carcinoma revealed by an isolated picture of primary hyperaldosteronism].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Adult; Aldosterone; Calcinosis; Female; Human

1988
Numerous mast cells in an 11-deoxycorticosterone-producing adrenocortical tumor. Histologic evaluation of benignancy and comparison with mast cell distribution in adrenal glands and neoplastic counterparts of 67 surgical specimens.
    Archives of pathology & laboratory medicine, 1985, Volume: 109, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Carcinoma, Renal Cell; Dehydroepiandro

1985
Primary aldosteronism by carcinoma of the adrenal cortex.
    Klinische Wochenschrift, 1987, May-04, Volume: 65, Issue:9

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Aldosterone; Combined Modality

1987
Preoperative lateralisation of aldosteronomas by aldosterone/cortisol ratios in adrenal venous plasma.
    Journal of human hypertension, 1987, Volume: 1, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperaldoster

1987
[Feminizing multi-secreting corticoadrenal carcinoma].
    Medicina clinica, 1988, Jan-30, Volume: 90, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Estrogens; Feminization; Humans; Male

1988
Adrenocortical carcinoma presenting as primary aldosteronism in a young man.
    Australian and New Zealand journal of medicine, 1987, Volume: 17, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Diagnosis, Differential; Humans; Hyperaldos

1987
New insights into the medical management of primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Fem

1986
A case report of aldosterone producing adenoma with masked hyperaldosteronemia.
    The Tokai journal of experimental and clinical medicine, 1986, Volume: 11, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Furosemide; Humans; Hyperaldosteronism; Midd

1986
Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Carcinoma; Cushing Syndrome; Desoxycort

1987
False localization of an aldosteronoma by dexamethasone-suppressed adrenal scintigraphy.
    Clinical endocrinology, 1987, Volume: 26, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cholesterol; Dexamethasone; Diagnostic Errors

1987
Calcium metabolism and parathyroid function in primary aldosteronism.
    The American journal of medicine, 1985, Volume: 78, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Calcium;

1985
Morphological changes in the adrenal cortex in different variants of low-renin hyperaldosteronism. Comparison with the functional state of certain hormonal systems.
    Cor et vasa, 1985, Volume: 27, Issue:2-3

    Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Hu

1985
Therapeutic effect of calcium channel blockade in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperal

1985
May a lymphocytic infiltration have a pathogenic role in an aldosterone-producing adrenal tumor?
    Medical hypotheses, 1985, Volume: 17, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Lymphocytes; Models, Biological

1985
Black (or brown) adrenal cortical adenoma: its characteristic features on computed tomography and endocrine data.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adult; Al

1985
Aldosterone-producing gigantic adrenocortical adenoma with calcifications and cysts.
    Urology, 1985, Volume: 26, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adult; Aldosterone; Calcinosis; Cysts; Hu

1985
[The effects of metoclopramide and dopamine on aldosterone secretion in cultured adrenocortical adenoma cells and adjacent non-adenoma cells from patients with primary aldosteronism].
    Nihon Naibunpi Gakkai zasshi, 1985, Jun-20, Volume: 61, Issue:6

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cells, Cultured; Chromatograp

1985
[Clinical picture, diagnosis and surgical treatment of aldosteromas].
    Klinicheskaia khirurgiia, 1985, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldoster

1985
[Renin-angiotensin-aldosterone system in pheochromocytoma].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Humans; Pheochromocy

1974
Malignant hypertension with aldosteronoma producing adenoma.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hype

1974
[Plasma renin activity and aldosterone excretion in patients with essential hypertension, with hypertension in bilateral adrenal cortex hyperplasia and with aldosterone-producing adrenal cortex adenomas following various sodium tolerance tests].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Adenoma; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldostero

1974