Page last updated: 2024-11-07

aldosterone and Acromegaly

aldosterone has been researched along with Acromegaly in 30 studies

Acromegaly: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)

Research Excerpts

ExcerptRelevanceReference
"In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations."5.28Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system. ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990)
"Treatment with bromocriptine resulted in a significant fall of systolic and diastolic blood pressure in supine and upright position accompanied by a marked reduction in plasma and urinary noradrenaline but without effect on adrenaline."5.26Effect of the dopamine agonist bromocriptine on blood pressure, catecholamines and renin activity in acromegalics at rest, following exercise and during insulin induced hypoglycemia. ( Hökfelt, B; Nilsson, A, 1978)
"Sixteen patients (five females, 11 males) with acromegaly were randomly assigned to receive 20 mg amiloride (an ENaC blocker) and 25 mg furosemide (a Na-K-2Cl cotransporter blocker) under a high-sodium diet to suppress endogenous renin and aldosterone."5.15Body fluid expansion in acromegaly is related to enhanced epithelial sodium channel (ENaC) activity. ( Azizi, M; Blanchard, A; Chanson, P; Frank, M; Kamenicky, P; Letierce, A; Lombès, M; Salenave, S, 2011)
"In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations."1.28Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system. ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990)
"Treatment with bromocriptine resulted in a significant fall of systolic and diastolic blood pressure in supine and upright position accompanied by a marked reduction in plasma and urinary noradrenaline but without effect on adrenaline."1.26Effect of the dopamine agonist bromocriptine on blood pressure, catecholamines and renin activity in acromegalics at rest, following exercise and during insulin induced hypoglycemia. ( Hökfelt, B; Nilsson, A, 1978)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199021 (70.00)18.7374
1990's5 (16.67)18.2507
2000's2 (6.67)29.6817
2010's2 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bielohuby, M1
Roemmler, J1
Manolopoulou, J1
Johnsen, I1
Sawitzky, M1
Schopohl, J1
Reincke, M1
Wolf, E1
Hoeflich, A1
Bidlingmaier, M1
Kamenicky, P1
Blanchard, A1
Frank, M1
Salenave, S1
Letierce, A1
Azizi, M1
Lombès, M1
Chanson, P1
Pappa, T1
Papanastasiou, L1
Koutmos, S1
Tsiavos, V1
Roussaki, P1
Zilos, A1
Ragkou, D1
Kaltsas, G1
Piaditis, G1
BENOIT, FL1
THEIL, GB1
WATTEN, RH1
Koga, Y1
Ohe, K1
Gondo, S1
Watanabe, T1
Sakamoto, R1
Nomura, M1
Okabe, T1
Kawazoe, N1
Sasano, K1
Yanase, T1
Molinatti, GM1
Limone, P1
Słowińska-Srzednicka, J2
Zgliczyński, S3
Puciłowska, J2
Strauch, G3
Moore, TJ1
Thein-Wai, W1
Dluhy, RG3
Dawson-Hughes, BF1
Hollenberg, NK1
Williams, GH3
Rioperez, E1
Botella, JM1
Valdivieso, L1
Ballesteros, D1
Diez, L1
Navas, J1
Karlberg, BE1
Ottosson, AM1
Bondanelli, M1
Ambrosio, MR1
Franceschetti, P1
Margutti, A1
Trasforini, G1
Degli Uberti, EC1
Nielson, KD1
Watts, C1
Clark, K1
Weitzman, ED1
Nilsson, A1
Hökfelt, B1
Ichikawa, S1
Sakamaki, T1
Tonooka, S1
Sugai, Y1
Soszyński, P1
Slowińska-Srzednicka, J1
Zacharieva, S2
Andreeva, M1
Andonova, K2
Kraatz, C1
Benker, G1
Weber, F1
Lüdecke, D1
Hirche, H1
Reinwein, D1
Stoeva, I1
Matrozov, P1
McKnight, JA1
McCance, DR1
Hadden, DR1
Kennedy, L1
Roberts, G1
Sheridan, B1
Atkinson, AB1
Czekalski, S1
Widecka, K1
Goździk, J1
Cain, JP1
Vallotton, MB2
Touitou, Y2
Bricaire, H2
Marek, J1
Horký, K1
Kopecká, J1
Mĕstan, J1
Srámková, J1
Ito, Y1
Werning, C1
Schweikert, HU1
Stiel, D1
Vetter, W1
Siegenthaler, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Physiopathology of Sodium Retention in Acromegaly[NCT00531908]12 participants (Actual)Interventional2007-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aldosterone and Acromegaly

ArticleYear
[The renin-angiotensin system. Physiopathological aspects and clinical implications of hypertensive syndromes. A survey].
    Minerva medica, 1981, Mar-31, Volume: 72, Issue:12

    Topics: Acromegaly; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Cushing Syndrome; Glycoproteins;

1981

Trials

1 trial available for aldosterone and Acromegaly

ArticleYear
Body fluid expansion in acromegaly is related to enhanced epithelial sodium channel (ENaC) activity.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:7

    Topics: Acromegaly; Aldosterone; Amiloride; Body Fluids; Cross-Over Studies; Diuretics; Edema; Epithelial So

2011

Other Studies

28 other studies available for aldosterone and Acromegaly

ArticleYear
Chronic growth hormone excess is associated with increased aldosterone: a study in patients with acromegaly and in growth hormone transgenic mice.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:8

    Topics: Acromegaly; Adrenal Glands; Aldosterone; Animals; Cattle; Cytochrome P-450 CYP11B2; Female; Human Gr

2009
Pattern of adrenal morphology and function in patients with acromegaly.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Female; Glucose Tolerance Test; Human Growth Hormone

2012
HYDROXYPROLINE EXCRETION IN ENDOCRINE DISEASE.
    Metabolism: clinical and experimental, 1963, Volume: 12

    Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Aldosterone; Anabolic Agents; Cushing Syndrome;

1963
[MEN type I presenting hypokalemia and hypertension, complicated with acromegaly, adrenal cortical tumor and rectal carcinoid tumor].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, Nov-10, Volume: 95, Issue:11

    Topics: Acromegaly; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Carcinoid Tumor; Female; Growt

2006
[Studies on the pathogenesis of arterial hypertension in acromegaly. I. The renin-angiotensin-aldosterone system].
    Polskie Archiwum Medycyny Wewnetrznej, 1983, Volume: 69, Issue:2

    Topics: Acromegaly; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Growth Hormone; Humans; Hydr

1983
[Strategy for hormonal study in the arterial hypertension of acromegaly].
    Annales de medecine interne, 1983, Volume: 134, Issue:3

    Topics: Acromegaly; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Body Fluid Compartments; Diet, Sodium-Res

1983
Abnormal adrenal and vascular responses to angiotensin II and an angiotensin antagonist in acromegaly.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:2

    Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restric

1980
Conn's syndrome in a patient with acromegaly.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1981, Volume: 13, Issue:3

    Topics: Acromegaly; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Female; Humans; Hyperten

1981
Acromegaly and hypertension: role of the renin-angiotensin-aldosterone system.
    Acta endocrinologica, 1982, Volume: 100, Issue:4

    Topics: Acromegaly; Adult; Aged; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male

1982
Diurnal rhythm of plasma catecholamines in acromegaly.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:7

    Topics: Acromegaly; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Epinephrine; Female; Heart Rate; H

1999
Transsphenoidal microsurgery for selective removal of functional pituitary microadenomas.
    World journal of surgery, 1977, Volume: 1, Issue:1

    Topics: Acromegaly; Adenoma; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aldosterone; Female;

1977
Biologic rhythms and hormone secretion patterns.
    Hospital practice, 1976, Volume: 11, Issue:8

    Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Amenorrhea; Child; Circadia

1976
Effect of the dopamine agonist bromocriptine on blood pressure, catecholamines and renin activity in acromegalics at rest, following exercise and during insulin induced hypoglycemia.
    Acta endocrinologica. Supplementum, 1978, Volume: 216

    Topics: Acromegaly; Aldosterone; Blood Pressure; Bromocriptine; Catecholamines; Dose-Response Relationship,

1978
The diurnal rhythm of plasma aldosterone, plasma renin activity, plasma cortisol and serum growth hormone and subnormal responsiveness of aldosterone to angiotensin-II in the patients with normotensive acromegaly.
    Endocrinologia japonica, 1976, Volume: 23, Issue:1

    Topics: Acromegaly; Adult; Aldosterone; Angiotensin II; Blood Pressure; Circadian Rhythm; Female; Growth Hor

1976
Plasma concentrations of atrial natriuretic hormone in acromegaly: relationship to hypertension.
    Acta endocrinologica, 1991, Volume: 125, Issue:3

    Topics: Acromegaly; Adult; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Fem

1991
Effect of sodium depletion on the renin-angiotensin-aldosterone system and renal prostaglandins in acromegalic patients.
    Experimental and clinical endocrinology, 1990, Volume: 96, Issue:2

    Topics: Acromegaly; Adult; Aldosterone; Blood Pressure; Dinoprostone; Female; Humans; Hyponatremia; Male; Mi

1990
Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system.
    Klinische Wochenschrift, 1990, Jun-19, Volume: 68, Issue:12

    Topics: Acromegaly; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Germany, West; Growth Horm

1990
Serum aldosterone response to metoclopramide in normal subjects and acromegalic patients.
    Experimental and clinical endocrinology, 1990, Volume: 95, Issue:3

    Topics: Acromegaly; Adult; Aldosterone; Dopamine; Female; Humans; Hypertension; Injections, Intravenous; Mal

1990
Basal and saline-stimulated levels of plasma atrial natriuretic factor in acromegaly.
    Clinical endocrinology, 1989, Volume: 31, Issue:4

    Topics: Acromegaly; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Male; Mid

1989
Plasma concentration of atrial natriuretic peptide (ANP) in patients with acromegaly.
    Endokrynologia Polska, 1989, Volume: 40, Issue:2

    Topics: Acromegaly; Adult; Aldosterone; Atrial Natriuretic Factor; Female; Growth Hormone; Humans; Male; Mid

1989
Arterial hypertension in acromegaly: altered dopaminergic control of aldosterone secretion.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:11

    Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Aldosterone; Cosyntropin; Female; Humans; Hypertensi

1987
Primary aldosteronism in a hypertensive acromegalic patient.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:10

    Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone

1969
Plasma renin activity and aldosterone secretion in patients with acromegaly.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:1

    Topics: Acromegaly; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Chlorides; Diet,

1972
The renin-angiotensin-aldosterone system in normotensive and hypertensive patients with acromegaly.
    The New England journal of medicine, 1972, Oct-19, Volume: 287, Issue:16

    Topics: Acromegaly; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Female; Growth Hormone; Hu

1972
Catecholamine excretion in acromegalics.
    Endokrinologie, 1974, Volume: 63, Issue:3

    Topics: 17-Hydroxycorticosteroids; Acromegaly; Adult; Aldosterone; Catecholamines; Chromatography, Paper; Ch

1974
The renin-aldosterone system in acromegaly: follow-up report.
    The New England journal of medicine, 1973, Oct-11, Volume: 289, Issue:15

    Topics: Acromegaly; Aldosterone; Follow-Up Studies; Humans; Renin

1973
[New method for the determination of 7 fractions of 17-deoxycorticosteroid (DOC, Comp. B, Comp. A, allo THB, THB, THA and aldosterone) and their urinary excretion. 2. Urinary excretion during normal menstrual cycle and in patients with various disease].
    Nihon Naibunpi Gakkai zasshi, 1972, Apr-20, Volume: 48, Issue:1

    Topics: 17-Hydroxycorticosteroids; Acromegaly; Adult; Aldosterone; Androgen-Insensitivity Syndrome; Collagen

1972
[Aldosterone and renin in acromegaly].
    Klinische Wochenschrift, 1970, Nov-15, Volume: 48, Issue:22

    Topics: Acromegaly; Adult; Aldosterone; Female; Humans; Male; Renin

1970