aldosterone has been researched along with ANS (Autonomic Nervous System) Diseases in 22 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study." | 6.42 | The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade. ( Davies, JI; Dawson, A; Struthers, AD, 2004) |
| "Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study." | 2.42 | The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade. ( Davies, JI; Dawson, A; Struthers, AD, 2004) |
| "Aldosterone has several deleterious properties." | 2.41 | Aldosterone: cardiovascular assault. ( Struthers, AD, 2002) |
| "Polyuria has been observed in a severe case of GBS occurring in a 16-year-old boy." | 1.28 | Polyuria during Guillain-Barré syndrome. ( De Coninck, B; Hantson, P; Horn, JL; Ketelslegers, JM; Mahieu, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grübler, MR | 1 |
| Kienreich, K | 1 |
| Gaksch, M | 1 |
| Verheyen, N | 1 |
| Hartaigh, BÓ | 1 |
| Fahrleitner-Pammer, A | 1 |
| März, W | 1 |
| Schmid, J | 1 |
| Oberreither, EM | 1 |
| Wetzel, J | 1 |
| Catena, C | 1 |
| Sechi, LA | 1 |
| Pieske, B | 1 |
| Tomaschitz, A | 1 |
| Pilz, S | 1 |
| Struthers, AD | 2 |
| Jarmuzewska, EA | 1 |
| Ghidoni, A | 1 |
| Mangoni, AA | 1 |
| VOELLM, KR | 1 |
| SCHAUB, F | 1 |
| DONOCIK, A | 1 |
| Dawson, A | 1 |
| Davies, JI | 1 |
| Garland, EM | 1 |
| Raj, SR | 1 |
| Black, BK | 1 |
| Harris, PA | 1 |
| Robertson, D | 1 |
| Sasaki, K | 1 |
| Murabayashi, S | 1 |
| Baba, T | 1 |
| Aoyagi, K | 1 |
| Matsunaga, M | 1 |
| Takebe, K | 1 |
| Nigawara, K | 1 |
| Stewart, AG | 1 |
| Waterhouse, JC | 1 |
| Billings, CG | 1 |
| Baylis, PH | 1 |
| Howard, P | 1 |
| Biaggioni, I | 1 |
| Garcia, F | 1 |
| Inagami, T | 1 |
| Haile, V | 1 |
| Salas-Ramírez, M | 1 |
| Ariza Andraca, R | 1 |
| Frati Munari, A | 1 |
| Muñoz, H | 1 |
| Altamirano, P | 1 |
| Tanaka, M | 1 |
| Shimizu, H | 1 |
| Monden, T | 1 |
| Mori, M | 1 |
| van Lieshout, JJ | 1 |
| ten Harkel, AD | 1 |
| Wieling, W | 1 |
| Monteagudo, PT | 1 |
| Gavras, H | 1 |
| Gavras, I | 1 |
| Kohlmann, O | 1 |
| Ribeiro, AB | 1 |
| Zanella, MT | 1 |
| Hantson, P | 1 |
| De Coninck, B | 1 |
| Horn, JL | 1 |
| Ketelslegers, JM | 1 |
| Mahieu, P | 1 |
| Voci, P | 1 |
| Bilotta, F | 1 |
| Viola, R | 1 |
| Haak, T | 1 |
| Jungmann, E | 1 |
| Neumann, M | 1 |
| Zeuzem, S | 1 |
| Schwietzer, G | 1 |
| Reschke, B | 1 |
| Althoff, PH | 1 |
| Schöffling, K | 1 |
| O'Hare, JP | 1 |
| Anderson, JV | 1 |
| Millar, ND | 1 |
| Dalton, N | 1 |
| Tymms, DJ | 1 |
| Bloom, SR | 1 |
| Corrall, RJ | 1 |
| Kikuchi, N | 1 |
| Nanno, M | 1 |
| Kurahachi, H | 1 |
| Yoshimi, T | 1 |
| Grimaldi, A | 1 |
| Pruszczynski, W | 1 |
| Thervet, F | 1 |
| Ardaillou, R | 1 |
| Coccagna, G | 1 |
| Martinelli, P | 1 |
| Zucconi, M | 1 |
| Cirignotta, F | 1 |
| Ambrosetto, G | 1 |
| Schalekamp, MA | 1 |
| Man in't Veld, AJ | 1 |
| Wenting, GJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Open Label, Blinded End Point Trial to Compare the Effects of Spironolactone With Chlortalidone on LV Mass in Stage 3 Chronic Kidney Disease (SPIRO-CKD)[NCT02502981] | Phase 4 | 154 participants (Actual) | Interventional | 2014-06-30 | Active, not recruiting | ||
| Estimating the Frequency and Neuro-Hormonal Characteristics of Acute Hepatic Porphyria in Postural Tachycardia Syndrome[NCT05344599] | 50 participants (Anticipated) | Observational | 2022-01-19 | Recruiting | |||
| Effect of Nebivolol on Blood Pressure in a Model of Hypertension Sensitive to Potentiation of Nitric Oxide Bioactivity[NCT01044693] | 20 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change from baseline (8 pm) in heart rate at the time of maximal BP-lowering effect (NCT01044693)
Timeframe: 8 pm - 8 am
| Intervention | bpm (Mean) |
|---|---|
| Placebo Capsule | -3 |
| Nebivolol 5 mg | -6 |
| Metoprolol Tartrate 50 mg | -6 |
| Sildenafil 25 mg | 0 |
Nocturnal sodium excretion was defined as the ratio of urinary sodium to urinary creatinine. (NCT01044693)
Timeframe: 8 pm - 8 am
| Intervention | mEq/mg (Mean) |
|---|---|
| Placebo Capsule | 0.145 |
| Nebivolol 5 mg | 0.127 |
| Metoprolol Tartrate 50 mg | 0.139 |
| Sildenafil 25 mg | 0.125 |
Orthostatic tolerance was defined as the area under the curve of standing systolic blood pressure calculated by the trapezoidal rule (upright systolic blood pressure multiplied by standing time) during a 10-minute standing test (NCT01044693)
Timeframe: 10 min standing
| Intervention | mm Hg*min (Mean) |
|---|---|
| Placebo Capsule | 594 |
| Nebivolol 5 mg | 675 |
| Metoprolol Tartrate 50 mg | 696 |
| Sildenafil 25 mg | 575 |
Maximal change from baseline in systolic blood pressure, measured from 8 pm to 8 am, after a single dose of the intervention (NCT01044693)
Timeframe: 8 pm - 8 am
| Intervention | mm Hg (Mean) | |
|---|---|---|
| Baseline supine at 8 pm | Change in systolic BP | |
| Metoprolol Tartrate 50 mg | 157 | -7 |
| Nebivolol 5 mg | 162 | -24 |
| Placebo Capsule | 154 | 1 |
| Sildenafil 25 mg | 158 | -20 |
4 reviews available for aldosterone and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Aldosterone: cardiovascular assault.
Topics: Aldosterone; Autonomic Nervous System Diseases; Cardiomegaly; Endothelium, Vascular; Fibrinolysis; F | 2002 |
[ON SO-CALLED "POSTURAL HYPOTENSION." HYPOTENSION DEPENDENT ON POSTURE IN IDIOPATHIC DISORDERS OF THE AUTONOMIC REGULATION OF CIRCULATION].
Topics: Aldosterone; Angiotensins; Autonomic Nervous System; Autonomic Nervous System Diseases; Desoxycortic | 1964 |
[METABOLIC DATA ON HYPERTENSION (ESSENTIAL HYPERTENSION)].
Topics: Adrenal Glands; Aldosterone; Angiotensins; Arteriosclerosis; Autonomic Nervous System Diseases; Cate | 1964 |
The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade.
Topics: Aldosterone; Autonomic Nervous System Diseases; Endomyocardial Fibrosis; Eplerenone; Heart Failure; | 2004 |
2 trials available for aldosterone and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
The hemodynamic and neurohumoral phenotype of postural tachycardia syndrome.
Topics: Adolescent; Adult; Aldosterone; Autonomic Nervous System Diseases; Biomarkers; Blood Pressure; Catec | 2007 |
Role of vasopressin in 24-hour blood pressure regulation in diabetic patients with autonomic neuropathy.
Topics: Adult; Aldosterone; Arginine Vasopressin; Autonomic Nervous System Diseases; Blood Pressure; Circadi | 2002 |
16 other studies available for aldosterone and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Aldosterone-to-Renin Ratio Is Associated With Reduced 24-Hour Heart Rate Variability and QTc Prolongation in Hypertensive Patients.
Topics: Adult; Aged; Aldosterone; Austria; Autonomic Nervous System Diseases; Blood Pressure; Blood Pressure | 2016 |
Relative preservation of the renin-angiotensin-aldosterone system response to active orthostatism in type 2 diabetic patients with autonomic neuropathy and postural hypotension.
Topics: Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Catecholamines; Diabetes Mellitus, T | 2003 |
The mechanism of aldosterone response to furosemide test in patients with Shy-Drager syndrome.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Autonomic Nervous System Diseases; Blood Pressure; Dexamet | 1983 |
Hormonal, renal, and autonomic nerve factors involved in the excretion of sodium and water during dynamic salt and water loading in hypoxaemic chronic obstructive pulmonary disease.
Topics: Aged; Aldosterone; Autonomic Nervous System Diseases; Glomerular Filtration Rate; Humans; Hypoxia; L | 1995 |
Hyporeninemic normoaldosteronism in severe autonomic failure.
Topics: Aged; Aldosterone; Autonomic Nervous System Diseases; Dopamine beta-Hydroxylase; Female; Humans; Imm | 1993 |
Effect of plasma volume expansion on auricular natriuretic peptide in non-dependent insulin diabetic patients with autonomic neuropathy.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Autonomic Nervous System Diseases; Diabetes Mellitus, | 1995 |
Edema due to altered sweating function.
Topics: Adult; Aldosterone; Autonomic Nervous System; Autonomic Nervous System Diseases; Baths; Body Weight; | 1993 |
Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failure.
Topics: Adult; Aged; Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Blood Volume; Cardiac O | 2000 |
Polyuria during Guillain-Barré syndrome.
Topics: Adolescent; Aldosterone; Atrial Natriuretic Factor; Autonomic Nervous System Diseases; Critical Care | 1992 |
Aldosterone-secreting adenoma and dysautonomic failure: the challenging association of 2 extreme conditions.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Autonomic Nervous System Diseases; Chronic Disease; H | 1991 |
[The influence of autonomic diabetic neuropathy and human atrial natriuretic peptide on adrenal gland function in postural changes].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Autonomic Nervous System Diseases; Diabetic Neuropath | 1991 |
Hormonal response to blood volume expansion in diabetic subjects with and without autonomic neuropathy.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Autonomic Nervous System Diseases; Blood Volume; Cate | 1989 |
[Autonomic neuropathy in diabetics--autonomic function and plasma catecholamines].
Topics: Adult; Aldosterone; Autonomic Nervous System; Autonomic Nervous System Diseases; Blood Pressure; Cat | 1988 |
Antidiuretic hormone response to volume depletion in diabetic patients with cardiac autonomic dysfunction.
Topics: Adult; Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Blood Volume; Diabetic Neurop | 1985 |
Sleep-related respiratory and haemodynamic changes in Shy-Drager syndrome: a case report.
Topics: Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Heart Rate; Humans; Male; Middle Age | 1985 |
The second Sir George Pickering memorial lecture. What regulates whole body autoregulation? Clinical observations.
Topics: Adult; Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Body Fluids; Cardiac Output; | 1985 |