albuterol has been researched along with Muscular Atrophy, Spinal in 7 studies
Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khirani, S | 1 |
| Dabaj, I | 1 |
| Amaddeo, A | 1 |
| Olmo Arroyo, J | 1 |
| Ropers, J | 1 |
| Tirolien, S | 1 |
| Coudert, V | 1 |
| Estournet, B | 1 |
| Fauroux, B | 1 |
| Quijano-Roy, S | 1 |
| Pera, MC | 1 |
| Luigetti, M | 1 |
| Sivo, S | 1 |
| Lapenta, L | 1 |
| Granata, G | 1 |
| Antonaci, L | 1 |
| Coratti, G | 1 |
| Forcina, N | 1 |
| Pane, M | 3 |
| Mercuri, E | 3 |
| Tiziano, FD | 3 |
| Lomastro, R | 2 |
| Abiusi, E | 1 |
| Pasanisi, MB | 2 |
| Di Pietro, L | 1 |
| Fiori, S | 2 |
| Baranello, G | 1 |
| Angelini, C | 1 |
| Sorarù, G | 1 |
| Gaiani, A | 1 |
| Mongini, T | 1 |
| Vercelli, L | 1 |
| Vasco, G | 1 |
| Vita, G | 2 |
| Messina, S | 2 |
| Petillo, R | 1 |
| Passamano, L | 1 |
| Politano, L | 1 |
| Campanella, A | 1 |
| Mantegazza, R | 1 |
| Morandi, L | 2 |
| Mack, SG | 1 |
| Cook, DJ | 1 |
| Dhurjati, P | 1 |
| Butchbach, ME | 1 |
| Giovannetti, AM | 1 |
| Černiauskaitė, M | 1 |
| Bussolino, C | 1 |
| Leonardi, M | 1 |
| Pinto, AM | 1 |
| D'Amico, A | 1 |
| Angelozzi, C | 2 |
| Bertini, E | 1 |
| Neri, G | 2 |
| Brahe, C | 2 |
| Borgo, F | 1 |
| Martella, A | 1 |
2 trials available for albuterol and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Longitudinal evaluation of SMN levels as biomarker for spinal muscular atrophy: results of a phase IIb double-blind study of salbutamol.
Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Biomarke | 2019 |
Salbutamol increases survival motor neuron (SMN) transcript levels in leucocytes of spinal muscular atrophy (SMA) patients: relevance for clinical trial design.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Child; Child, Preschool; Female; Gene Express | 2010 |
5 other studies available for albuterol and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Effect of Salbutamol on Respiratory Muscle Strength in Spinal Muscular Atrophy.
Topics: Administration, Oral; Albuterol; Bronchodilator Agents; Child; Child, Preschool; Female; Humans; Mal | 2017 |
Does albuterol have an effect on neuromuscular junction dysfunction in spinal muscular atrophy?
Topics: Albuterol; Child; Female; Humans; Male; Middle Aged; Muscular Atrophy, Spinal; Neuromuscular Agents; | 2018 |
Systems biology investigation of cAMP modulation to increase SMN levels for the treatment of spinal muscular atrophy.
Topics: Albuterol; Bucladesine; Colforsin; Cyclic AMP; Epinephrine; Fibroblasts; Fluorescent Antibody Techni | 2014 |
Perceived efficacy of salbutamol by persons with spinal muscular atrophy: A mixed methods study.
Topics: Adult; Albuterol; Bronchodilator Agents; Female; Humans; Longitudinal Studies; Male; Middle Aged; Mu | 2016 |
Salbutamol increases SMN mRNA and protein levels in spinal muscular atrophy cells.
Topics: Adrenergic beta-Agonists; Albuterol; Cyclic AMP Response Element-Binding Protein; Exons; Fibroblasts | 2008 |