albuterol has been researched along with Muscle Relaxation in 125 studies
Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
Excerpt | Relevance | Reference |
---|---|---|
"Tremor was recorded with a 3-dimensional accelerometer during three different states of hand extensor muscle activity: relaxed, lightly and maximally contracted." | 6.66 | Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol. ( Reeh, PW; Schaffler, K, 1987) |
" Their airway smooth muscle relaxant potencies and effect on histamine contraction in human bronchi in vitro were compared with their effects on airway calibre and histamine reactivity in asthmatic subjects in vivo." | 5.07 | Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo. ( Baldwin, DR; Knox, AJ; Pavord, ID; Sivardeen, Z, 1994) |
" Smooth muscle relaxation was obtained by salbutamol and l-phenylephrine, whereas contraction was achieved by carbachol and 1-(3-chlorophenyl)-biguanide." | 3.72 | Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis. ( Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ, 2003) |
"We examined the effects of four beta 2-agonists, clenbuterol, metaproterenol, procaterol, and albuterol, on the contractility of fatigued canine diaphragm." | 3.68 | Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo. ( Miyashita, A; Numata, H; Okubo, T; Suzuki, M; Suzuki, S, 1993) |
"Pre-treatment with propranolol totally inhibited the effect of both drugs." | 2.68 | Airway effects of salmeterol in healthy individuals. ( Bake, B; Bergendal, A; Johansson, A; Löfdahl, CG; Lötvall, J; Skoogh, BE, 1995) |
"Tremor was recorded with a 3-dimensional accelerometer during three different states of hand extensor muscle activity: relaxed, lightly and maximally contracted." | 2.66 | Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol. ( Reeh, PW; Schaffler, K, 1987) |
"IL-1Ra treatment prevented hyperoxia-induced alveolar disruption and airway fibrosis but, surprisingly, not the increase in methacholine-induced airway contraction." | 1.43 | Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist. ( Bourke, JE; Bui, C; Donovan, C; Lam, M; Lamanna, E; Nold, MF; Nold-Petry, CA; Royce, SG; Rudloff, I, 2016) |
" Levcromakalim produced concentration-dependent inhibitory effect on myometrial spontaneity and relaxant effect and the dose-response curve (DRC) was shifted towards right in the presence of glybenclamaide." | 1.36 | Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Mishra, SK; Singh, TU, 2010) |
" CRH with P4 pretreatment caused a 40 +/- 13% (n = 4) reduction in contractility, whereas in matched samples, CRH alone exerted a 26 +/- 6% (n = 4) reduction, with a shift of CRH dose-response curves (P < 0." | 1.35 | Evidence that corticotropin-releasing hormone modulates myometrial contractility during human pregnancy. ( Read, M; Smith, R; Tyson, EK, 2009) |
" The dose-response curve to isoproterenol in naive sphincters or sphincters pre-treated with atropine indicated that muscarinic blockade decreased the EC(50) rather than potentiated maximal beta-adrenergic relaxation." | 1.32 | Muscarinic blockers potentiate beta-adrenergic relaxation of bovine iris sphincter. ( Barilan, A; Geyer, O; Nachman-Rubinstein, R; Oron, Y, 2003) |
"Ibudilast was equipotent to attenuate the precontractions induced by both 0." | 1.31 | Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle. ( Ishii, K; Mitani, A; Moriuchi, H; Nakahara, T; Sakamoto, K; Yunoki, M, 2002) |
"Pretreatment with furosemide diminished relaxation response to salbutamol [87 +/- 3% (n = 11) vs." | 1.30 | Cross-desensitization to furosemide and salbutamol in isolated neonatal guinea pig airways. ( Christ, MJ; Fujiwara, N; Gelber, RP; Iwamoto, LM; Marinkovich, GA; Nakamura, KT, 1999) |
"Siguazodan was 100 fold more active than rolipram in pig tissues indicating the type III isoenzyme may be of greater functional significance in this tissue." | 1.29 | Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes. ( Karlsson, JA; Raeburn, D; Tomkinson, A, 1993) |
"Cromakalim was able to produce an additional relaxation response in the presence of a maximal relaxation induced by salbutamol and theophylline." | 1.29 | [Effects of the potassium channel activator cromakalim on human isolated bronchial smooth muscle]. ( Liu, J; Luo, Y; Zhou, L, 1995) |
"5." | 1.29 | Comparison of the profiles of agonists as stimulants of the beta 3-adrenoceptor in vitro with their gastroprotective effects in the conscious rat. ( Bahl, AK; Clayton, NM; Coates, J; Martin, DP; Oakley, IG; Strong, P; Trevethick, MA, 1996) |
"In our experiments hyperthyroidism has a sensitizing influence on vascular responses induced by the beta-adrenoceptor agonist isoproterenol and the selective beta 2-adrenoceptor agonist salbutamol." | 1.29 | The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries. ( Pfaffendorf, M; van Zwieten, PA; Winkler Prins, EA; Zwaveling, J, 1996) |
"2." | 1.28 | One way cross tolerance between cromakalim and salbutamol in the uterus of the rat in vivo. ( Downing, SJ; Hollingsworth, M, 1992) |
"Theophylline was markedly less potent than any of the other agents." | 1.28 | Evaluation of the bronchodilator properties of Ro 31-6930, a novel potassium channel opener, in the guinea-pig. ( Cowlrick, IS; Paciorek, PM; Perkins, RS; Taylor, JC; Waterfall, JF; Wilkinson, GF, 1990) |
"Pretreatment with reserpine increased the potency of salbutamol at each concentration of carbachol." | 1.27 | The effect of varying carbachol concentration on the slope of Schild plots of selective beta-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea. ( Donahue, JY; Keith, RA; Salama, AI, 1986) |
" Both contractile cholinergic responses and relaxant nonadrenergic noncholinergic dose-response data were obtained for the in vitro bronchial specimens by electrical field stimulation." | 1.27 | Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro. ( Armour, CL; Hogg, JC; Paré, PD; Schellenberg, RR; Taylor, SM, 1985) |
" Dose-response curves to the relaxant effects of isoprenaline, salbutamol, adrenaline and noradrenaline were determined on the partially contracted smooth muscles of the cat nictitating membrane following alpha-adrenoreceptor blockade in order to test the hypothesis of a causal relationship between the inhibition of neuronal uptake and denervation supersensitivity." | 1.26 | Denervation and beta-adrenoreceptors of the cat nictitating membrane. ( Nickerson, M; Varma, DR, 1981) |
" Construction of dose-response curves, however, revealed antagonism of all three parameters by propranolol and different sensitivities of the parameters to isoprenaline." | 1.26 | The beta-adrenoceptors responsible for a direct relaxation of the uncontracted nictitating membrane of the anaesthetized cat. ( Broadley, KJ, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (14.40) | 18.7374 |
1990's | 68 (54.40) | 18.2507 |
2000's | 25 (20.00) | 29.6817 |
2010's | 12 (9.60) | 24.3611 |
2020's | 2 (1.60) | 2.80 |
Authors | Studies |
---|---|
Jen, T | 2 |
Frazee, JS | 2 |
Schwartz, MS | 2 |
Kaiser, C | 2 |
Erhard, KF | 1 |
Buckle, DR | 2 |
Arch, JR | 3 |
Fenwick, AE | 1 |
Houge-Frydrych, CS | 1 |
Pinto, IL | 1 |
Smith, DG | 1 |
Taylor, SG | 2 |
Tedder, JM | 1 |
Carbajal-García, A | 1 |
Reyes-García, J | 1 |
Casas-Hernández, MF | 1 |
Flores-Soto, E | 1 |
Díaz-Hernández, V | 1 |
Solís-Chagoyán, H | 1 |
Sommer, B | 1 |
Montaño, LM | 1 |
Muddle, J | 1 |
Kanabar, V | 1 |
Brown, M | 1 |
Page, C | 1 |
Forbes, B | 1 |
Hegde, SS | 1 |
Hughes, AD | 1 |
Chen, Y | 1 |
Steinfeld, T | 1 |
Jasper, JR | 1 |
Lee, TW | 1 |
McNamara, A | 1 |
Martin, WJ | 1 |
Pulido-Rios, MT | 1 |
Mammen, M | 1 |
Rodríguez-Ramos, F | 1 |
Andrade-Moreno, MÁ | 1 |
Alfaro-Romero, A | 1 |
Balderas-López, JL | 1 |
Navarrete, A | 1 |
Royce, SG | 1 |
Nold, MF | 1 |
Bui, C | 1 |
Donovan, C | 1 |
Lam, M | 1 |
Lamanna, E | 1 |
Rudloff, I | 1 |
Bourke, JE | 1 |
Nold-Petry, CA | 1 |
Angulo, M | 1 |
Taranto, E | 1 |
Soto, JP | 1 |
Malacrida, L | 1 |
Nin, N | 1 |
Hurtado, FJ | 1 |
Píriz, H | 1 |
Delmotte, P | 1 |
Sanderson, MJ | 1 |
Tyson, EK | 1 |
Smith, R | 1 |
Read, M | 1 |
Adner, M | 2 |
Larsson, B | 1 |
Säfholm, J | 2 |
Naya, I | 1 |
Miller-Larsson, A | 1 |
Choudhury, S | 1 |
Garg, SK | 1 |
Singh, TU | 1 |
Mishra, SK | 1 |
Montalvo, F | 1 |
Cantres-Fonseca, O | 1 |
Santos, G | 1 |
Vega, M | 1 |
Torres, I | 1 |
Carmona, J | 1 |
Dexter, D | 1 |
Santacana, G | 1 |
Soriano-Ursúa, MA | 1 |
Correa-Basurto, J | 1 |
Valencia-Hernández, I | 1 |
Amezcua-Gutiérrez, MA | 1 |
Padilla-Martínez, II | 1 |
Trujillo-Ferrara, JG | 1 |
Suárez, L | 1 |
Pipa, M | 1 |
Granda, J | 1 |
Coto, A | 1 |
Bordallo, J | 1 |
Cantabrana, B | 1 |
García de Boto, MJ | 1 |
Sánchez, M | 1 |
Nicholls, DJ | 1 |
Jordan, S | 1 |
Cadogan, E | 1 |
Lawson, M | 1 |
Austin, RP | 2 |
Paine, SW | 1 |
Gardiner, P | 1 |
Bonnert, R | 1 |
Connolly, S | 1 |
Young, A | 2 |
An, SS | 1 |
Wang, WC | 1 |
Koziol-White, CJ | 1 |
Ahn, K | 1 |
Lee, DY | 1 |
Kurten, RC | 1 |
Panettieri, RA | 1 |
Liggett, SB | 1 |
Pulkkinen, V | 1 |
Manson, ML | 1 |
Dahlén, SE | 1 |
Nakahara, T | 5 |
Yunoki, M | 5 |
Moriuchi, H | 5 |
Mitani, A | 1 |
Sakamoto, K | 1 |
Ishii, K | 5 |
Barilan, A | 1 |
Nachman-Rubinstein, R | 1 |
Oron, Y | 2 |
Geyer, O | 2 |
Zijlstra, FJ | 1 |
van Meeteren, ME | 1 |
Garrelds, IM | 1 |
Meijssen, MA | 1 |
Yamanishi, T | 4 |
Chapple, CR | 3 |
Yasuda, K | 4 |
Yoshida, K | 4 |
Chess-Williams, R | 3 |
Barton, P | 1 |
Bonnert, RV | 1 |
Brown, RC | 1 |
Cage, PA | 1 |
Cheshire, DR | 1 |
Davis, AM | 1 |
Dougall, IG | 1 |
Ince, F | 1 |
Pairaudeau, G | 1 |
Koike, K | 5 |
Yamashita, Y | 3 |
Horinouchi, T | 5 |
Yamaki, F | 1 |
Tanaka, Y | 4 |
Dorion, G | 1 |
Israël-Assayag, E | 1 |
Beaulieu, MJ | 1 |
Cormier, Y | 1 |
Badawi, JK | 1 |
Uecelehan, H | 1 |
Hatzinger, M | 1 |
Michel, MS | 1 |
Haferkamp, A | 1 |
Bross, S | 1 |
Vizioli, EO | 1 |
Spadin, MD | 1 |
Corrêa, FM | 1 |
Viaro, F | 1 |
Evora, PR | 1 |
Chies, AB | 1 |
Kitahara, S | 1 |
Nakai, H | 1 |
Iizuka, H | 1 |
Michikawa, H | 1 |
Mendes, ES | 1 |
Horvath, G | 1 |
Rebolledo, P | 1 |
Monzon, ME | 1 |
Casalino-Matsuda, SM | 1 |
Wanner, A | 1 |
Varma, DR | 1 |
Nickerson, M | 1 |
van der Heijden, PJ | 1 |
van Amsterdam, JG | 1 |
Zaagsma, J | 1 |
Grassby, PF | 1 |
Broadley, KJ | 2 |
Tomioka, K | 1 |
Yamada, T | 1 |
Tachikawa, S | 1 |
Sekizawa, K | 1 |
Sasaki, H | 1 |
Okubo, T | 2 |
Shimizu, Y | 1 |
Akaizawa, Y | 1 |
Takishima, T | 1 |
Weissinger, J | 1 |
Bloor, C | 1 |
Marinkovich, GA | 2 |
Pichoff, BE | 1 |
Iwamoto, LM | 2 |
Dressel, MV | 1 |
Nakamura, KT | 2 |
Tamaoki, J | 3 |
Tagaya, E | 2 |
Chiyotani, A | 2 |
Yamawaki, I | 2 |
Konno, K | 2 |
Randall, MD | 1 |
McCulloch, AI | 1 |
Huang, JC | 1 |
Garcia, ML | 2 |
Reuben, JP | 1 |
Kacsorowski, GJ | 1 |
Ohnishi, H | 1 |
Maeda, H | 1 |
Nishimura, Y | 1 |
Takenaka, K | 1 |
Yahata, T | 1 |
Takatsuki, K | 1 |
Nakamura, H | 1 |
Yokoyama, M | 1 |
Baldwin, DR | 1 |
Sivardeen, Z | 1 |
Pavord, ID | 1 |
Knox, AJ | 1 |
Numata, H | 1 |
Suzuki, S | 1 |
Miyashita, A | 1 |
Suzuki, M | 1 |
Miyamoto, K | 1 |
Kurita, M | 1 |
Sakai, R | 1 |
Sanae, F | 1 |
Wakusawa, S | 1 |
Takagi, K | 1 |
Yamauchi, F | 1 |
Takeuchi, S | 1 |
Nials, AT | 3 |
Sumner, MJ | 1 |
Johnson, M | 3 |
Coleman, RA | 3 |
Graves, J | 1 |
Poston, L | 1 |
Jones, TR | 1 |
Charette, L | 1 |
Kaczorowski, GJ | 1 |
Lindén, A | 6 |
Bergendal, A | 3 |
Ullman, A | 1 |
Skoogh, BE | 3 |
Löfdahl, CG | 4 |
Imagawa, J | 1 |
Yoshida, S | 1 |
Koga, T | 1 |
Kamei, K | 1 |
Nabata, H | 1 |
Ball, DI | 2 |
Butchers, PR | 1 |
Humbles, AA | 1 |
Vardey, CJ | 1 |
Tomkinson, A | 1 |
Karlsson, JA | 1 |
Raeburn, D | 1 |
Conroy, DM | 2 |
St-Pierre, S | 1 |
Sirois, P | 1 |
Hashjin, GS | 1 |
Henricks, PA | 1 |
Folkerts, G | 1 |
Nijkamp, FP | 1 |
Luo, Y | 1 |
Liu, J | 1 |
Zhou, L | 1 |
Ellis, KE | 1 |
Mistry, R | 1 |
Boyle, JP | 1 |
Challiss, RA | 1 |
Hirsh, AJ | 1 |
Benishin, CG | 1 |
Jones, RL | 1 |
Pang, PK | 1 |
Man, SF | 1 |
Rabe, KF | 1 |
Johansson, A | 1 |
Bake, B | 1 |
Lötvall, J | 1 |
Bahl, AK | 1 |
Clayton, NM | 1 |
Coates, J | 1 |
Martin, DP | 1 |
Oakley, IG | 1 |
Strong, P | 1 |
Trevethick, MA | 1 |
Redemann, B | 1 |
Vaali, K | 1 |
Li, L | 1 |
Paakkari, I | 1 |
Vapaatalo, H | 1 |
Planquois, JM | 1 |
Ruffin-Morin, Y | 1 |
Lagente, V | 1 |
Payne, AN | 1 |
Dahl, SG | 1 |
Gerspacher, M | 1 |
Anderson, GP | 1 |
Donaldson, LL | 1 |
Myers, AK | 1 |
Zwaveling, J | 1 |
Winkler Prins, EA | 1 |
Pfaffendorf, M | 1 |
van Zwieten, PA | 1 |
Yoshihara, S | 3 |
Kashimoto, K | 3 |
Nagano, Y | 2 |
Ichimura, T | 2 |
Nadel, JA | 2 |
Wachsman, DE | 1 |
Kavaler, JP | 1 |
Sugár, IP | 1 |
Schachter, EN | 1 |
Gonsiorek, W | 1 |
Maayani, S | 1 |
Buchheit, KH | 1 |
Hofmann, A | 1 |
Pfannkuche, HJ | 1 |
Müller-Schweinitzer, E | 1 |
Fozard, JR | 1 |
Mulder, P | 1 |
Compagnon, P | 1 |
Devaux, B | 1 |
Richard, V | 1 |
Henry, JP | 1 |
Elfertak, L | 1 |
Wimart, MC | 1 |
Thibout, E | 1 |
Comoy, E | 1 |
Macé, B | 1 |
Thuillez, C | 1 |
Corompt, E | 1 |
Bessard, G | 1 |
Lantuejoul, S | 1 |
Naline, E | 2 |
Advenier, C | 2 |
Devillier, P | 1 |
Watanabe, S | 1 |
Ichino, T | 1 |
Takayanagi, I | 1 |
Hernández, M | 1 |
Elmedal, B | 1 |
Mulvany, MJ | 1 |
Simonsen, U | 1 |
Bar-Ilan, A | 1 |
Nachman, R | 1 |
Lazar, M | 1 |
Isono, K | 1 |
Nagai, A | 1 |
Törneke, K | 1 |
Ingvast Larsson, C | 1 |
Appelgren, LE | 1 |
Blanc, FX | 1 |
Salmeron, S | 1 |
Coirault, C | 1 |
Bard, M | 1 |
Fadel, E | 1 |
Dulmet, E | 1 |
Dartevelle, P | 1 |
Lecarpentier, Y | 1 |
Yousif, MH | 1 |
Thulesius, O | 1 |
Priest, RM | 1 |
Hucks, D | 1 |
Ward, JP | 1 |
Groeben, H | 1 |
Emala, C | 1 |
Gelber, RP | 1 |
Christ, MJ | 1 |
Fujiwara, N | 1 |
Rong, Y | 1 |
Arbabian, M | 1 |
Thiriot, DS | 1 |
Seibold, A | 1 |
Clark, RB | 1 |
Ruoho, AE | 1 |
Clayton, RA | 1 |
Nally, JE | 1 |
MacLean, MR | 1 |
Thomson, NC | 1 |
McGrath, JC | 1 |
Sakamato, K | 4 |
Small, RC | 1 |
Chiu, P | 1 |
Cook, SJ | 1 |
Foster, RW | 1 |
Isaac, L | 1 |
Kubota, Y | 2 |
Shigenobu, K | 1 |
Bardou, M | 1 |
Loustalot, C | 1 |
Cortijo, J | 1 |
Simon, B | 1 |
Dumas, M | 1 |
Esteve, S | 1 |
Croci, T | 1 |
Chalon, P | 1 |
Frydman, R | 1 |
Sagot, P | 1 |
Manara, L | 1 |
Morcillo, EJ | 1 |
Källström, BL | 2 |
Waldeck, B | 2 |
Fayon, MJ | 1 |
Denis, D | 1 |
Molimard, M | 1 |
Berger, P | 1 |
Choukroun, ML | 1 |
Demarquez, JL | 1 |
Marthan, R | 1 |
Clevel, H | 1 |
Lachaud, JL | 1 |
Martinez, B | 1 |
Téchoueyres, P | 1 |
Lau, YS | 1 |
Lum, BK | 1 |
Kitamura, S | 2 |
Ishihara, Y | 2 |
Kosaka, K | 1 |
Fukushima, Y | 1 |
Downing, SJ | 1 |
Hollingsworth, M | 1 |
Gray, DW | 1 |
Marshall, I | 1 |
Sauder, RA | 1 |
Tobias, JD | 1 |
Hirshman, CA | 1 |
Filbert, MG | 1 |
Moore, DH | 1 |
Adler, M | 1 |
Jeppsson, AB | 1 |
Oztürk, Y | 1 |
Yildizoğlu-Ari, N | 1 |
Altan, N | 1 |
Altan, VM | 1 |
Foster, KA | 1 |
Newson, PN | 1 |
Shaw, D | 1 |
Janssen, LJ | 1 |
Daniel, EE | 1 |
Brittain, RT | 1 |
Denyer, LH | 1 |
Jack, D | 1 |
Lunts, LH | 1 |
Sheldrick, KE | 1 |
Skidmore, IF | 1 |
Kikkawa, H | 1 |
Naito, K | 1 |
Ikezawa, K | 1 |
Colbert, WE | 1 |
Williams, PD | 1 |
Williams, GD | 1 |
Yang, JN | 1 |
Mitzner, W | 1 |
Hirshman, C | 1 |
Bowring, NE | 1 |
Clarke, GD | 1 |
Taylor, JF | 1 |
Bramley, AM | 1 |
Samhoun, MN | 2 |
Piper, PJ | 2 |
Guia, A | 1 |
Bose, R | 1 |
Paciorek, PM | 1 |
Cowlrick, IS | 1 |
Perkins, RS | 1 |
Taylor, JC | 1 |
Wilkinson, GF | 1 |
Waterfall, JF | 1 |
Uchida, Y | 1 |
Takaku, F | 1 |
Olson, LE | 1 |
Perkowski, SZ | 1 |
Mason, DE | 1 |
Muir, WW | 1 |
Keith, RA | 1 |
Donahue, JY | 1 |
Salama, AI | 1 |
Schaffler, K | 1 |
Reeh, PW | 1 |
White, RE | 1 |
Jolly, SR | 1 |
Carrier, GO | 1 |
Rydningen, HT | 1 |
Omland, T | 1 |
Opstad, PK | 1 |
Helle, KB | 1 |
Taylor, SM | 1 |
Paré, PD | 1 |
Armour, CL | 1 |
Hogg, JC | 1 |
Schellenberg, RR | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers[NCT01216735] | 32 participants (Actual) | Interventional | 2008-09-30 | Completed | |||
A Randomized, Controlled,14-Treatment Day, Multicenter Study to Determine the Optimal Efficacious and Safe Dose of CHF 4226 in a Metered Dose Inhaler in Treating Patients With Chronic Obstructive Pulmonary Disease[NCT00605891] | Phase 2 | 278 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
Evaluation of the Effect of 2 Weeks Treatment With CHF 4226 pMDI 2µg and 4µg, Given Once Daily in the Morning, on 24-Hour FEV1 in Patients With COPD[NCT00640484] | Phase 2 | 57 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Airway Blood flow (Qaw) will be measured before and 15 minutes after albuterol inhalation (delta Qaw). (NCT01216735)
Timeframe: 3 weeks treatment period of ICS or placebo
Intervention | % change (Mean) |
---|---|
Fluticasone | 40.9 |
Placebo | 0.0 |
Flow-mediated vasodilation response in the brachial artery will be measured before and 15 minutes.after albuterol inhalation (NCT01216735)
Timeframe: 3 weeks of treatment
Intervention | % change (Mean) |
---|---|
Fluticasone | 3.9 |
Placebo | 4.8 |
1 review available for albuterol and Muscle Relaxation
Article | Year |
---|---|
Pharmacological basis for duration of effect: formoterol and salmeterol versus short-acting beta 2-adrenoceptor agonists.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Bronchodilator Agents; Ethanolamines; Formote | 1996 |
3 trials available for albuterol and Muscle Relaxation
Article | Year |
---|---|
Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo.
Topics: Adult; Albuterol; Asthma; Bronchoconstriction; Cross-Over Studies; Culture Techniques; Dose-Response | 1994 |
Airway effects of salmeterol in healthy individuals.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol; | 1995 |
Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Blood Pressure; Electromyography; Heart Rate; Humans; Is | 1987 |
121 other studies available for albuterol and Muscle Relaxation
Article | Year |
---|---|
Adrenerigic agents. 7.1 Synthesis and beta-adrenergic agonist activity of several 2-pyridylethanolamines.
Topics: Adrenergic beta-Agonists; Animals; Ethanolamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Musc | 1977 |
Adrenergic agents. 8.1 Synthesis and beta-adrenergic agonist activity of some 3-tert-butylamino-2-(substituted phenyl)-1-propanols.
Topics: Adrenergic beta-Agonists; Animals; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation; | 1977 |
Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis.
Topics: Amides; Animals; Benzopyrans; Bronchodilator Agents; Chemical Phenomena; Chemistry; Cromakalim; Guin | 1990 |
Testosterone augments β
Topics: Albuterol; Animals; Cycloheximide; Dactinomycin; Genome; Guinea Pigs; Lung; Male; Muscle Cells; Musc | 2020 |
An in vitro bioassay for evaluating the effect of inhaled bronchodilators on airway smooth muscle.
Topics: Albuterol; Biological Assay; Bronchodilator Agents; Humans; Muscle Relaxation; Muscle, Smooth | 2020 |
Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.
Topics: Adrenergic beta-2 Receptor Antagonists; Albuterol; Animals; Bronchodilator Agents; Carbamates; CHO C | 2014 |
Gnaphaliin A and gnaphaliin B synergize the relaxant effect of salbutamol but not of ipratropium in guinea pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Synergism; Flavono | 2016 |
Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist.
Topics: Airway Remodeling; Albuterol; Animals; Bronchial Hyperreactivity; Bronchopulmonary Dysplasia; Diseas | 2016 |
[Salbutamol improves diaphragmatic contractility in chronic airway obstruction].
Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Alkalosis; Animals; Chronic Disease; Diaphr | 2009 |
Effects of formoterol on contraction and Ca2+ signaling of mouse airway smooth muscle cells.
Topics: Albuterol; Animals; Calcium Signaling; Ethanolamines; Formoterol Fumarate; In Vitro Techniques; Intr | 2010 |
Evidence that corticotropin-releasing hormone modulates myometrial contractility during human pregnancy.
Topics: Adult; Albuterol; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; | 2009 |
Budesonide prevents cytokine-induced decrease of the relaxant responses to formoterol and terbutaline, but not to salmeterol, in mouse trachea.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Bronchodilator Agents; Budesonide; Cyclic A | 2010 |
Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis).
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Albuterol; Animals; Buffaloes; Cromakalim; Female; Glybur | 2010 |
Nitric oxide is involved in the response of the isolated intact and epithelium-denuded rat trachea to the β₂ adrenergic receptor agonist salbutamol.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Carbachol; Cholinergic Agonists; Electric S | 2010 |
Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: a novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Binding Sites; Computer Simulation; Drug De | 2010 |
Sex hormones modulate salbutamol-elicited long-term relaxation in isolated bovine tracheal strips.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; Carba | 2011 |
Characteristics of AZD9708, a novel, selective β2-adrenoceptor agonist with rapid onset and long duration of action.
Topics: Adenosine Monophosphate; Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Asthma; Benzothiaz | 2012 |
TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chloroquine; Humans; In Vitro Techniques; Isoprotereno | 2012 |
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Carbachol; Charybdotoxin; Chloroquine; Cholinergic Agonis | 2012 |
Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle.
Topics: Albuterol; Analysis of Variance; Animals; Atrial Natriuretic Factor; Bronchodilator Agents; Cattle; | 2002 |
Muscarinic blockers potentiate beta-adrenergic relaxation of bovine iris sphincter.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Dose-Response Relationship, Drug; Drug Synergi | 2003 |
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female; | 2003 |
Role of beta-adrenoceptor subtypes in mediating relaxation of the pig bladder trigonal muscle in vitro.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dose-Response Relationshi | 2003 |
QSAR and the rational design of long-acting dual D2-receptor/beta 2-adrenoceptor agonists.
Topics: Adrenergic beta-Agonists; Albuterol; Algorithms; Animals; Biological Transport; Dopamine Agonists; D | 2003 |
The functional role of beta-adrenoceptor subtypes in mediating relaxation of pig urethral smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Ethanolamines; Female; Im | 2003 |
cAMP-independent mechanism is significantly involved in beta2-adrenoceptor-mediated tracheal relaxation.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonist | 2004 |
Effect of 1,1-dimethylphenyl 1,4-piperazinium on mouse tracheal smooth muscle responsiveness.
Topics: Albuterol; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bronchoconstrictor Agents; Bronchodilat | 2005 |
Adrenaline produces the relaxation of guinea-pig airway smooth muscle primarily through the mediation of beta(2)-adrenoceptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dose-Response Relationshi | 2005 |
Relaxant effects of beta-adrenergic agonists on porcine and human detrusor muscle.
Topics: Adrenergic beta-Agonists; Aged; Albuterol; Animals; Dioxoles; Dose-Response Relationship, Drug; Epin | 2005 |
Acetylcholine-induced aortic relaxation studied in salbutamol treated rats.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Aorta, Thoracic; Cyclic AMP; Dose-Respo | 2005 |
Effects of 138-355, a beta3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albutero | 2006 |
Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; A | 2007 |
Effect of an inhaled glucocorticoid on endothelial function in healthy smokers.
Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Androstadienes; Bronchodilator Agents; End | 2008 |
Denervation and beta-adrenoreceptors of the cat nictitating membrane.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Cats; Epinephrine; Female; In Vitro Techniques; Iso | 1981 |
Desensitization of smooth muscle and mast cell beta-adrenoceptors in the airways of the guinea pig.
Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Clenbuterol; Dose-Response Relationship, Drug; Fenote | 1984 |
Characterization of beta-adrenoceptors mediating relaxation of the guinea-pig ileum.
Topics: Albuterol; Animals; Electric Stimulation; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Is | 1984 |
Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats.
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Anaphylaxis; Animals; Cromolyn Sodium; Ethan | 1984 |
Effect of bronchomotor tone on work rate of breathing.
Topics: Adult; Aerosols; Airway Resistance; Albuterol; Bronchi; Humans; Lung Compliance; Male; Methacholine | 1984 |
Heterogeneous response patterns of aortae to norepinephrine.
Topics: Albuterol; Animals; Aorta, Abdominal; Aorta, Thoracic; Epinephrine; Male; Muscle Contraction; Muscle | 1980 |
Acute hyperoxic injury attenuates the relaxing effects of "loop" diuretics and salbutamol on large airways of newborn guinea pigs.
Topics: Albuterol; Animals; Animals, Newborn; Bronchi; Bronchodilator Agents; Diuretics; Ethacrynic Acid; Fe | 1995 |
Role of K+ channel opening and Na(+)-K+ ATPase activity in airway relaxation induced by salbutamol.
Topics: Albuterol; Analysis of Variance; Animals; Apamin; Bronchi; Charybdotoxin; Dogs; Dose-Response Relati | 1994 |
The involvement of ATP-sensitive potassium channels in beta-adrenoceptor-mediated vasorelaxation in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; B | 1995 |
Inhibition of beta-adrenoceptor agonist relaxation of airway smooth muscle by Ca(2+)-activated K+ channel blockers.
Topics: Acetylcholine; Albuterol; Animals; Cadmium; Cadmium Chloride; Calcium; Calcium Channels; Charybdotox | 1993 |
[Bronchial hyperresponsiveness and relaxability in patients with mitral stenosis].
Topics: Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Met | 1994 |
Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Clenbuterol; Diaphragm; Dogs; Dose-Res | 1993 |
Cyclic nucleotide phosphodiesterase isoenzymes in guinea-pig tracheal muscle and bronchorelaxation by alkylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Ag | 1994 |
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; C | 1993 |
Investigations into factors determining the duration of action of the beta 2-adrenoceptor agonist, salmeterol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Electric Stimulation; Gui | 1993 |
Beta-adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Arginine; Colforsin; Cyclic AMP; Dobutamine; Endotheli | 1993 |
Interaction of iberiotoxin with beta-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Drug Interactions; Guinea Pigs; In Vitro Techniques; I | 1993 |
Salmeterol, formoterol, and salbutamol in the isolated guinea pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanolam | 1993 |
The effect of a novel benzopyran derivative, KC 399, on the isolated guinea-pig trachealis and human bronchi.
Topics: Albuterol; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Cromakalim; Guinea Pigs; Humans; In | 1993 |
Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol.
Topics: Albuterol; Animals; Bronchi; Bronchodilator Agents; Cells, Cultured; Dinoprost; Electric Stimulation | 1994 |
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In V | 1993 |
Relaxant effects of pituitary adenylate cyclase activating polypeptide (PACAP) on epithelium-intact and -denuded guinea-pig trachea: a comparison with vasoactive intestinal peptide (VIP).
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Arginine; Bronchi; Cyclooxygenase Inhibitors; Epitheli | 1995 |
Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies.
Topics: Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; Fem | 1995 |
[Effects of the potassium channel activator cromakalim on human isolated bronchial smooth muscle].
Topics: Adult; Albuterol; Benzopyrans; Bronchi; Bronchodilator Agents; Cromakalim; Drug Synergism; Female; H | 1995 |
Correlation of cyclic AMP accumulation and relaxant actions of salmeterol and salbutamol in bovine tracheal smooth muscle.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Cyclic AM | 1995 |
Calcium mobilization and isometric tension in bovine tracheal smooth muscle: effects of salbutamol and histamine.
Topics: Albuterol; Aniline Compounds; Animals; Bronchodilator Agents; Calcium; Cattle; Colforsin; Electrophy | 1996 |
Comparison of the profiles of agonists as stimulants of the beta 3-adrenoceptor in vitro with their gastroprotective effects in the conscious rat.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Ag | 1996 |
Effects of potassium-channel opener HOE 234 in guinea-pig airways.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Bronchodilator Agents; Chromans; Cyclooxygena | 1996 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug S | 1996 |
Extent of salmeterol-mediated reassertion of relaxation in guinea-pig trachea pretreated with aliphatic side chain structural analogues.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Dose-Response Relationship, Dru | 1996 |
Effect of pharmacological agonists on contractile responses in aortic rings derived from endotoxaemic rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Analysis of Variance; | 1996 |
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adren | 1996 |
A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Captopril; Glycopeptides; Guinea Pigs; In Vitro Technique | 1996 |
Kinetic studies of desensitization and resensitization of the relaxation response to beta-2 adrenoceptor agonists in isolated guinea pig trachea.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Guinea | 1997 |
In vitro and in vivo effects of SCA40 on guinea pig airways.
Topics: Albuterol; Animals; Blood Pressure; Bombesin; Bronchoconstriction; Bronchodilator Agents; Guinea Pig | 1997 |
SCA 40: studies of the relaxant effects on cryopreserved human airway and vascular smooth muscle.
Topics: Albuterol; Bronchi; Carbachol; Cryopreservation; Drug Interactions; Humans; Imidazoles; Muscle Relax | 1997 |
Response of large and small vessels to alpha and beta adrenoceptor stimulation in heart failure: effect of angiotensin converting enzyme inhibition.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Angiotensin-Convertin | 1997 |
Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro.
Topics: Albuterol; Animals; Bronchi; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs | 1997 |
Inhibitory effects of large Ca2+-activated K+ channel blockers on beta-adrenergic- and NO-donor-mediated relaxations of human and guinea-pig airway smooth muscles.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Animals; Benzimidazoles; Bronch | 1998 |
A novel long-acting VIP analog in the guinea pig trachea in vitro.
Topics: Albuterol; Amino Acid Sequence; Animals; Captopril; Carbachol; Guinea Pigs; Male; Molecular Sequence | 1998 |
The beta2- and beta3-adrenoceptor-mediated relaxation induced by isoprenaline and salbutamol in guinea pig taenia caecum.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cecum; Dose-Respo | 1997 |
Mechanisms of relaxations of bovine isolated bronchioles by the nitric oxide donor, GEA 3175.
Topics: Albuterol; Aminoquinolines; Animals; Apamin; Bronchi; Bronchodilator Agents; Cattle; Charybdotoxin; | 1998 |
Beta3-adrenergic relaxation of bovine iris sphincter.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bupranolol; Cattle; Colfo | 1998 |
Atypical adrenoceptor-mediated relaxation of canine pulmonary artery through a cAMP-dependent pathway.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cyclic AMP; Dioxoles; Dog | 1998 |
A comparison between clenbuterol, salbutamol and terbutaline in relation to receptor binding and in vitro relaxation of equine tracheal muscle.
Topics: Albuterol; Animals; Binding, Competitive; Bronchodilator Agents; Clenbuterol; Dose-Response Relation | 1998 |
Effects of load and tone on the mechanics of isolated human bronchial smooth muscle.
Topics: Albuterol; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Data Interpretation, Statistic | 1999 |
Forskolin reverses tachyphylaxis to the bronchodilator effects of salbutamol: an in-vitro study on isolated guinea-pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Colforsin; Dose-Response Relationship, Drug; Drug Synergi | 1999 |
Potentiation of cyclic AMP-mediated vasorelaxation by phenylephrine in pulmonary arteries of the rat.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Colforsin | 1999 |
Is beta-adrenergic-mediated airway relaxation of salmeterol antagonized by its solvent xinafoic acid?
Topics: Administration, Inhalation; Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronch | 1999 |
Cross-desensitization to furosemide and salbutamol in isolated neonatal guinea pig airways.
Topics: Acetylcholine; Albuterol; Animals; Animals, Newborn; Bronchodilator Agents; Cyclic AMP; Drug Toleran | 1999 |
Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Albu | 1999 |
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibi | 1999 |
Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Albuterol; Amides; Animals; Bronchoconstrictor Agents; Bronchodilator Agen | 2000 |
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 1993 |
Lidocaine potentiates the relaxant effects of cAMP-elevating agents in bovine tracheal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Anesthetics, Local; Animals; Bupivacaine; Cattle; Colforsin; | 2000 |
Involvement of K(+) channel in procainamide-induced relaxation of bovine tracheal smooth muscle.
Topics: Albuterol; Animals; Anti-Arrhythmia Agents; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle | 2000 |
Functional, biochemical and molecular biological evidence for a possible beta(3)-adrenoceptor in human near-term myometrium.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol; Cyclic AMP; Cyclic GMP; Dos | 2000 |
Functional properties of atypical beta-adrenoceptors on the guinea pig duodenum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprenolol; Animals; Bupranolol; C | 2001 |
Mexiletine inhibits pharmacological actions of salbutamol through blockade of beta2-adrenoceptors in bovine tracheal smooth muscle.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Anti-Arrhythmia Agents; Bronchodilator Agents; Catt | 2001 |
Bronchodilating properties of the VIP receptor agonist Ro 25-1553 compared to those of formoterol on the guinea-pig isolated trachea.
Topics: Albuterol; Amino Acid Sequence; Animals; Bronchodilator Agents; Carbachol; Dose-Response Relationshi | 2001 |
The role of beta(3)-adrenoceptors in mediating relaxation of porcine detrusor muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Binding, Competitive; Dos | 2002 |
Pharmacologically induced relaxation of tracheal smooth muscle is increased in hyperoxia-exposed 15-day-old rats.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Animals, Newborn; Hyperoxia; Muscle Relaxation; Muscle | 2002 |
The beta-adrenoceptors responsible for a direct relaxation of the uncontracted nictitating membrane of the anaesthetized cat.
Topics: Albuterol; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Isop | 1977 |
Role of cyclic AMP in adrenergically induced tracheal smooth muscle relaxation.
Topics: Albuterol; Animals; Cattle; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Muscle Cont | 1977 |
Effect of ACTH on the relaxation of guinea pig trachea with various bronchodilators.
Topics: Adrenocorticotropic Hormone; Airway Resistance; Albuterol; Aminophylline; Animals; Bronchodilator Ag | 1978 |
One way cross tolerance between cromakalim and salbutamol in the uterus of the rat in vivo.
Topics: Albuterol; Animals; Benzopyrans; Cromakalim; Cyclic AMP; Drug Interactions; Drug Tolerance; Female; | 1992 |
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascu | 1992 |
Methylprednisolone restores sensitivity to beta-adrenergic agonists in Basenji-Greyhound dogs.
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Aminophylline; Animals; Dogs; Drug Resistanc | 1992 |
Relaxation of soman-induced contracture of airway smooth muscle in vitro.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Colforsin; Dogs; Dose-Response Relation | 1992 |
Studies on the interaction between formoterol and salmeterol in guinea-pig trachea in vitro.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Drug Interactions; Electric Sti | 1992 |
Effect of lithium on gastro-intestinal complications in alloxan-diabetic rats.
Topics: Albuterol; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Duodenum; Gastrointestinal Disea | 1992 |
Effect of Rb+ on cromakalim-induced relaxation and ion fluxes in guinea pig trachea.
Topics: Albuterol; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Guinea Pigs; In Vitro Techniques | 1992 |
Classification of postjunctional beta adrenoceptors mediating relaxation of canine bronchi.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Calcium; Carbachol; Dogs; Electric Stimulatio | 1991 |
Salmeterol, a novel, long-acting beta 2-adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Dinoprost; Electric Stimulation | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Beta-adrenoceptor profile of ractopamine HCl in isolated smooth and cardiac muscle tissues of rat and guinea-pig.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Female; Guinea Pigs; Heart; In Vitro Techniques; Isopr | 1991 |
Role of the epithelium in airway smooth muscle responses to relaxant agonists.
Topics: Albuterol; Animals; Arachidonic Acid; Bronchodilator Agents; Diffusion; Epithelium; Guinea Pigs; In | 1991 |
Evaluation of the potassium channel activator BRL 38227 as an inhaled bronchodilator in the guinea-pig: contrast with nifedipine and salbutamol.
Topics: Administration, Inhalation; Airway Resistance; Albuterol; Aminophylline; Animals; Benzopyrans; Bronc | 1991 |
The role of the epithelium in modulating the responses of guinea-pig trachea induced by bradykinin in vitro.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bradyk | 1990 |
Effects of extracellular acidosis on the action of smooth muscle relaxants.
Topics: Acidosis; Albuterol; Amiloride; Animals; Carbachol; Dogs; In Vitro Techniques; Isometric Contraction | 1990 |
Relaxations of guinea-pig isolated trachea induced by platelet-activating factor are epithelial-dependent and are antagonised by WEB 2086.
Topics: Albuterol; Animals; Azepines; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Musc | 1990 |
Evaluation of the bronchodilator properties of Ro 31-6930, a novel potassium channel opener, in the guinea-pig.
Topics: Albuterol; Anesthesia; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Decerebrate State; D | 1990 |
Effect of coenzyme Q10, a quinone derivative, on guinea pig lung and tracheal tissue.
Topics: Albuterol; Animals; Coenzymes; Dinoprost; Dinoprostone; Guinea Pigs; Histamine Release; In Vitro Tec | 1985 |
Isoproterenol- and salbutamol-induced relaxation of acetylcholine- and histamine-induced contraction of equine trachealis muscle in vitro.
Topics: Acetylcholine; Albuterol; Analysis of Variance; Animals; Culture Techniques; Histamine; Horses; Isop | 1989 |
The effect of varying carbachol concentration on the slope of Schild plots of selective beta-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Carbachol; Guinea Pigs; In Vitro Techniqu | 1986 |
Enhanced relaxation response of canine coronary artery to isoproterenol and salbutamol after removal of endothelial cells.
Topics: Acetylcholine; Albuterol; Animals; Coronary Vessels; Dogs; Endothelium; In Vitro Techniques; Isoprot | 1986 |
Comparison of VIP and beta 2-adrenoceptor-induced relaxations in the circular and longitudinal smooth muscle layers of the rat portal vein.
Topics: Albuterol; Animals; Apamin; Female; Isoproterenol; Methoxamine; Muscle Contraction; Muscle Relaxatio | 1987 |
Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro.
Topics: Aged; Albuterol; Bronchi; Bronchial Provocation Tests; Colforsin; Diterpenes; Female; Forced Expirat | 1985 |