Page last updated: 2024-10-22

albuterol and Muscle Relaxation

albuterol has been researched along with Muscle Relaxation in 125 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"Tremor was recorded with a 3-dimensional accelerometer during three different states of hand extensor muscle activity: relaxed, lightly and maximally contracted."6.66Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol. ( Reeh, PW; Schaffler, K, 1987)
" Their airway smooth muscle relaxant potencies and effect on histamine contraction in human bronchi in vitro were compared with their effects on airway calibre and histamine reactivity in asthmatic subjects in vivo."5.07Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo. ( Baldwin, DR; Knox, AJ; Pavord, ID; Sivardeen, Z, 1994)
" Smooth muscle relaxation was obtained by salbutamol and l-phenylephrine, whereas contraction was achieved by carbachol and 1-(3-chlorophenyl)-biguanide."3.72Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis. ( Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ, 2003)
"We examined the effects of four beta 2-agonists, clenbuterol, metaproterenol, procaterol, and albuterol, on the contractility of fatigued canine diaphragm."3.68Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo. ( Miyashita, A; Numata, H; Okubo, T; Suzuki, M; Suzuki, S, 1993)
"Pre-treatment with propranolol totally inhibited the effect of both drugs."2.68Airway effects of salmeterol in healthy individuals. ( Bake, B; Bergendal, A; Johansson, A; Löfdahl, CG; Lötvall, J; Skoogh, BE, 1995)
"Tremor was recorded with a 3-dimensional accelerometer during three different states of hand extensor muscle activity: relaxed, lightly and maximally contracted."2.66Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol. ( Reeh, PW; Schaffler, K, 1987)
"IL-1Ra treatment prevented hyperoxia-induced alveolar disruption and airway fibrosis but, surprisingly, not the increase in methacholine-induced airway contraction."1.43Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist. ( Bourke, JE; Bui, C; Donovan, C; Lam, M; Lamanna, E; Nold, MF; Nold-Petry, CA; Royce, SG; Rudloff, I, 2016)
" Levcromakalim produced concentration-dependent inhibitory effect on myometrial spontaneity and relaxant effect and the dose-response curve (DRC) was shifted towards right in the presence of glybenclamaide."1.36Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Mishra, SK; Singh, TU, 2010)
" CRH with P4 pretreatment caused a 40 +/- 13% (n = 4) reduction in contractility, whereas in matched samples, CRH alone exerted a 26 +/- 6% (n = 4) reduction, with a shift of CRH dose-response curves (P < 0."1.35Evidence that corticotropin-releasing hormone modulates myometrial contractility during human pregnancy. ( Read, M; Smith, R; Tyson, EK, 2009)
" The dose-response curve to isoproterenol in naive sphincters or sphincters pre-treated with atropine indicated that muscarinic blockade decreased the EC(50) rather than potentiated maximal beta-adrenergic relaxation."1.32Muscarinic blockers potentiate beta-adrenergic relaxation of bovine iris sphincter. ( Barilan, A; Geyer, O; Nachman-Rubinstein, R; Oron, Y, 2003)
"Ibudilast was equipotent to attenuate the precontractions induced by both 0."1.31Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle. ( Ishii, K; Mitani, A; Moriuchi, H; Nakahara, T; Sakamoto, K; Yunoki, M, 2002)
"Pretreatment with furosemide diminished relaxation response to salbutamol [87 +/- 3% (n = 11) vs."1.30Cross-desensitization to furosemide and salbutamol in isolated neonatal guinea pig airways. ( Christ, MJ; Fujiwara, N; Gelber, RP; Iwamoto, LM; Marinkovich, GA; Nakamura, KT, 1999)
"Siguazodan was 100 fold more active than rolipram in pig tissues indicating the type III isoenzyme may be of greater functional significance in this tissue."1.29Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes. ( Karlsson, JA; Raeburn, D; Tomkinson, A, 1993)
"Cromakalim was able to produce an additional relaxation response in the presence of a maximal relaxation induced by salbutamol and theophylline."1.29[Effects of the potassium channel activator cromakalim on human isolated bronchial smooth muscle]. ( Liu, J; Luo, Y; Zhou, L, 1995)
"5."1.29Comparison of the profiles of agonists as stimulants of the beta 3-adrenoceptor in vitro with their gastroprotective effects in the conscious rat. ( Bahl, AK; Clayton, NM; Coates, J; Martin, DP; Oakley, IG; Strong, P; Trevethick, MA, 1996)
"In our experiments hyperthyroidism has a sensitizing influence on vascular responses induced by the beta-adrenoceptor agonist isoproterenol and the selective beta 2-adrenoceptor agonist salbutamol."1.29The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries. ( Pfaffendorf, M; van Zwieten, PA; Winkler Prins, EA; Zwaveling, J, 1996)
"2."1.28One way cross tolerance between cromakalim and salbutamol in the uterus of the rat in vivo. ( Downing, SJ; Hollingsworth, M, 1992)
"Theophylline was markedly less potent than any of the other agents."1.28Evaluation of the bronchodilator properties of Ro 31-6930, a novel potassium channel opener, in the guinea-pig. ( Cowlrick, IS; Paciorek, PM; Perkins, RS; Taylor, JC; Waterfall, JF; Wilkinson, GF, 1990)
"Pretreatment with reserpine increased the potency of salbutamol at each concentration of carbachol."1.27The effect of varying carbachol concentration on the slope of Schild plots of selective beta-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea. ( Donahue, JY; Keith, RA; Salama, AI, 1986)
" Both contractile cholinergic responses and relaxant nonadrenergic noncholinergic dose-response data were obtained for the in vitro bronchial specimens by electrical field stimulation."1.27Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro. ( Armour, CL; Hogg, JC; Paré, PD; Schellenberg, RR; Taylor, SM, 1985)
" Dose-response curves to the relaxant effects of isoprenaline, salbutamol, adrenaline and noradrenaline were determined on the partially contracted smooth muscles of the cat nictitating membrane following alpha-adrenoreceptor blockade in order to test the hypothesis of a causal relationship between the inhibition of neuronal uptake and denervation supersensitivity."1.26Denervation and beta-adrenoreceptors of the cat nictitating membrane. ( Nickerson, M; Varma, DR, 1981)
" Construction of dose-response curves, however, revealed antagonism of all three parameters by propranolol and different sensitivities of the parameters to isoprenaline."1.26The beta-adrenoceptors responsible for a direct relaxation of the uncontracted nictitating membrane of the anaesthetized cat. ( Broadley, KJ, 1977)

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-199018 (14.40)18.7374
1990's68 (54.40)18.2507
2000's25 (20.00)29.6817
2010's12 (9.60)24.3611
2020's2 (1.60)2.80

Authors

AuthorsStudies
Jen, T2
Frazee, JS2
Schwartz, MS2
Kaiser, C2
Erhard, KF1
Buckle, DR2
Arch, JR3
Fenwick, AE1
Houge-Frydrych, CS1
Pinto, IL1
Smith, DG1
Taylor, SG2
Tedder, JM1
Carbajal-García, A1
Reyes-García, J1
Casas-Hernández, MF1
Flores-Soto, E1
Díaz-Hernández, V1
Solís-Chagoyán, H1
Sommer, B1
Montaño, LM1
Muddle, J1
Kanabar, V1
Brown, M1
Page, C1
Forbes, B1
Hegde, SS1
Hughes, AD1
Chen, Y1
Steinfeld, T1
Jasper, JR1
Lee, TW1
McNamara, A1
Martin, WJ1
Pulido-Rios, MT1
Mammen, M1
Rodríguez-Ramos, F1
Andrade-Moreno, MÁ1
Alfaro-Romero, A1
Balderas-López, JL1
Navarrete, A1
Royce, SG1
Nold, MF1
Bui, C1
Donovan, C1
Lam, M1
Lamanna, E1
Rudloff, I1
Bourke, JE1
Nold-Petry, CA1
Angulo, M1
Taranto, E1
Soto, JP1
Malacrida, L1
Nin, N1
Hurtado, FJ1
Píriz, H1
Delmotte, P1
Sanderson, MJ1
Tyson, EK1
Smith, R1
Read, M1
Adner, M2
Larsson, B1
Säfholm, J2
Naya, I1
Miller-Larsson, A1
Choudhury, S1
Garg, SK1
Singh, TU1
Mishra, SK1
Montalvo, F1
Cantres-Fonseca, O1
Santos, G1
Vega, M1
Torres, I1
Carmona, J1
Dexter, D1
Santacana, G1
Soriano-Ursúa, MA1
Correa-Basurto, J1
Valencia-Hernández, I1
Amezcua-Gutiérrez, MA1
Padilla-Martínez, II1
Trujillo-Ferrara, JG1
Suárez, L1
Pipa, M1
Granda, J1
Coto, A1
Bordallo, J1
Cantabrana, B1
García de Boto, MJ1
Sánchez, M1
Nicholls, DJ1
Jordan, S1
Cadogan, E1
Lawson, M1
Austin, RP2
Paine, SW1
Gardiner, P1
Bonnert, R1
Connolly, S1
Young, A2
An, SS1
Wang, WC1
Koziol-White, CJ1
Ahn, K1
Lee, DY1
Kurten, RC1
Panettieri, RA1
Liggett, SB1
Pulkkinen, V1
Manson, ML1
Dahlén, SE1
Nakahara, T5
Yunoki, M5
Moriuchi, H5
Mitani, A1
Sakamoto, K1
Ishii, K5
Barilan, A1
Nachman-Rubinstein, R1
Oron, Y2
Geyer, O2
Zijlstra, FJ1
van Meeteren, ME1
Garrelds, IM1
Meijssen, MA1
Yamanishi, T4
Chapple, CR3
Yasuda, K4
Yoshida, K4
Chess-Williams, R3
Barton, P1
Bonnert, RV1
Brown, RC1
Cage, PA1
Cheshire, DR1
Davis, AM1
Dougall, IG1
Ince, F1
Pairaudeau, G1
Koike, K5
Yamashita, Y3
Horinouchi, T5
Yamaki, F1
Tanaka, Y4
Dorion, G1
Israël-Assayag, E1
Beaulieu, MJ1
Cormier, Y1
Badawi, JK1
Uecelehan, H1
Hatzinger, M1
Michel, MS1
Haferkamp, A1
Bross, S1
Vizioli, EO1
Spadin, MD1
Corrêa, FM1
Viaro, F1
Evora, PR1
Chies, AB1
Kitahara, S1
Nakai, H1
Iizuka, H1
Michikawa, H1
Mendes, ES1
Horvath, G1
Rebolledo, P1
Monzon, ME1
Casalino-Matsuda, SM1
Wanner, A1
Varma, DR1
Nickerson, M1
van der Heijden, PJ1
van Amsterdam, JG1
Zaagsma, J1
Grassby, PF1
Broadley, KJ2
Tomioka, K1
Yamada, T1
Tachikawa, S1
Sekizawa, K1
Sasaki, H1
Okubo, T2
Shimizu, Y1
Akaizawa, Y1
Takishima, T1
Weissinger, J1
Bloor, C1
Marinkovich, GA2
Pichoff, BE1
Iwamoto, LM2
Dressel, MV1
Nakamura, KT2
Tamaoki, J3
Tagaya, E2
Chiyotani, A2
Yamawaki, I2
Konno, K2
Randall, MD1
McCulloch, AI1
Huang, JC1
Garcia, ML2
Reuben, JP1
Kacsorowski, GJ1
Ohnishi, H1
Maeda, H1
Nishimura, Y1
Takenaka, K1
Yahata, T1
Takatsuki, K1
Nakamura, H1
Yokoyama, M1
Baldwin, DR1
Sivardeen, Z1
Pavord, ID1
Knox, AJ1
Numata, H1
Suzuki, S1
Miyashita, A1
Suzuki, M1
Miyamoto, K1
Kurita, M1
Sakai, R1
Sanae, F1
Wakusawa, S1
Takagi, K1
Yamauchi, F1
Takeuchi, S1
Nials, AT3
Sumner, MJ1
Johnson, M3
Coleman, RA3
Graves, J1
Poston, L1
Jones, TR1
Charette, L1
Kaczorowski, GJ1
Lindén, A6
Bergendal, A3
Ullman, A1
Skoogh, BE3
Löfdahl, CG4
Imagawa, J1
Yoshida, S1
Koga, T1
Kamei, K1
Nabata, H1
Ball, DI2
Butchers, PR1
Humbles, AA1
Vardey, CJ1
Tomkinson, A1
Karlsson, JA1
Raeburn, D1
Conroy, DM2
St-Pierre, S1
Sirois, P1
Hashjin, GS1
Henricks, PA1
Folkerts, G1
Nijkamp, FP1
Luo, Y1
Liu, J1
Zhou, L1
Ellis, KE1
Mistry, R1
Boyle, JP1
Challiss, RA1
Hirsh, AJ1
Benishin, CG1
Jones, RL1
Pang, PK1
Man, SF1
Rabe, KF1
Johansson, A1
Bake, B1
Lötvall, J1
Bahl, AK1
Clayton, NM1
Coates, J1
Martin, DP1
Oakley, IG1
Strong, P1
Trevethick, MA1
Redemann, B1
Vaali, K1
Li, L1
Paakkari, I1
Vapaatalo, H1
Planquois, JM1
Ruffin-Morin, Y1
Lagente, V1
Payne, AN1
Dahl, SG1
Gerspacher, M1
Anderson, GP1
Donaldson, LL1
Myers, AK1
Zwaveling, J1
Winkler Prins, EA1
Pfaffendorf, M1
van Zwieten, PA1
Yoshihara, S3
Kashimoto, K3
Nagano, Y2
Ichimura, T2
Nadel, JA2
Wachsman, DE1
Kavaler, JP1
Sugár, IP1
Schachter, EN1
Gonsiorek, W1
Maayani, S1
Buchheit, KH1
Hofmann, A1
Pfannkuche, HJ1
Müller-Schweinitzer, E1
Fozard, JR1
Mulder, P1
Compagnon, P1
Devaux, B1
Richard, V1
Henry, JP1
Elfertak, L1
Wimart, MC1
Thibout, E1
Comoy, E1
Macé, B1
Thuillez, C1
Corompt, E1
Bessard, G1
Lantuejoul, S1
Naline, E2
Advenier, C2
Devillier, P1
Watanabe, S1
Ichino, T1
Takayanagi, I1
Hernández, M1
Elmedal, B1
Mulvany, MJ1
Simonsen, U1
Bar-Ilan, A1
Nachman, R1
Lazar, M1
Isono, K1
Nagai, A1
Törneke, K1
Ingvast Larsson, C1
Appelgren, LE1
Blanc, FX1
Salmeron, S1
Coirault, C1
Bard, M1
Fadel, E1
Dulmet, E1
Dartevelle, P1
Lecarpentier, Y1
Yousif, MH1
Thulesius, O1
Priest, RM1
Hucks, D1
Ward, JP1
Groeben, H1
Emala, C1
Gelber, RP1
Christ, MJ1
Fujiwara, N1
Rong, Y1
Arbabian, M1
Thiriot, DS1
Seibold, A1
Clark, RB1
Ruoho, AE1
Clayton, RA1
Nally, JE1
MacLean, MR1
Thomson, NC1
McGrath, JC1
Sakamato, K4
Small, RC1
Chiu, P1
Cook, SJ1
Foster, RW1
Isaac, L1
Kubota, Y2
Shigenobu, K1
Bardou, M1
Loustalot, C1
Cortijo, J1
Simon, B1
Dumas, M1
Esteve, S1
Croci, T1
Chalon, P1
Frydman, R1
Sagot, P1
Manara, L1
Morcillo, EJ1
Källström, BL2
Waldeck, B2
Fayon, MJ1
Denis, D1
Molimard, M1
Berger, P1
Choukroun, ML1
Demarquez, JL1
Marthan, R1
Clevel, H1
Lachaud, JL1
Martinez, B1
Téchoueyres, P1
Lau, YS1
Lum, BK1
Kitamura, S2
Ishihara, Y2
Kosaka, K1
Fukushima, Y1
Downing, SJ1
Hollingsworth, M1
Gray, DW1
Marshall, I1
Sauder, RA1
Tobias, JD1
Hirshman, CA1
Filbert, MG1
Moore, DH1
Adler, M1
Jeppsson, AB1
Oztürk, Y1
Yildizoğlu-Ari, N1
Altan, N1
Altan, VM1
Foster, KA1
Newson, PN1
Shaw, D1
Janssen, LJ1
Daniel, EE1
Brittain, RT1
Denyer, LH1
Jack, D1
Lunts, LH1
Sheldrick, KE1
Skidmore, IF1
Kikkawa, H1
Naito, K1
Ikezawa, K1
Colbert, WE1
Williams, PD1
Williams, GD1
Yang, JN1
Mitzner, W1
Hirshman, C1
Bowring, NE1
Clarke, GD1
Taylor, JF1
Bramley, AM1
Samhoun, MN2
Piper, PJ2
Guia, A1
Bose, R1
Paciorek, PM1
Cowlrick, IS1
Perkins, RS1
Taylor, JC1
Wilkinson, GF1
Waterfall, JF1
Uchida, Y1
Takaku, F1
Olson, LE1
Perkowski, SZ1
Mason, DE1
Muir, WW1
Keith, RA1
Donahue, JY1
Salama, AI1
Schaffler, K1
Reeh, PW1
White, RE1
Jolly, SR1
Carrier, GO1
Rydningen, HT1
Omland, T1
Opstad, PK1
Helle, KB1
Taylor, SM1
Paré, PD1
Armour, CL1
Hogg, JC1
Schellenberg, RR1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers[NCT01216735]32 participants (Actual)Interventional2008-09-30Completed
A Randomized, Controlled,14-Treatment Day, Multicenter Study to Determine the Optimal Efficacious and Safe Dose of CHF 4226 in a Metered Dose Inhaler in Treating Patients With Chronic Obstructive Pulmonary Disease[NCT00605891]Phase 2278 participants (Actual)Interventional2006-10-31Completed
Evaluation of the Effect of 2 Weeks Treatment With CHF 4226 pMDI 2µg and 4µg, Given Once Daily in the Morning, on 24-Hour FEV1 in Patients With COPD[NCT00640484]Phase 257 participants (Actual)Interventional2008-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Albuterol Induced Change in Qaw Before and After Fluticasone or Placebo

Airway Blood flow (Qaw) will be measured before and 15 minutes after albuterol inhalation (delta Qaw). (NCT01216735)
Timeframe: 3 weeks treatment period of ICS or placebo

Intervention% change (Mean)
Fluticasone40.9
Placebo0.0

Flow-mediated Brachial Vasodilation (FMD% Peak Delta)

Flow-mediated vasodilation response in the brachial artery will be measured before and 15 minutes.after albuterol inhalation (NCT01216735)
Timeframe: 3 weeks of treatment

Intervention% change (Mean)
Fluticasone3.9
Placebo4.8

Reviews

1 review available for albuterol and Muscle Relaxation

ArticleYear
Pharmacological basis for duration of effect: formoterol and salmeterol versus short-acting beta 2-adrenoceptor agonists.
    Lung, 1996, Volume: 174, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Bronchodilator Agents; Ethanolamines; Formote

1996

Trials

3 trials available for albuterol and Muscle Relaxation

ArticleYear
Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo.
    Thorax, 1994, Volume: 49, Issue:11

    Topics: Adult; Albuterol; Asthma; Bronchoconstriction; Cross-Over Studies; Culture Techniques; Dose-Response

1994
Airway effects of salmeterol in healthy individuals.
    Pulmonary pharmacology, 1995, Volume: 8, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol;

1995
Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:12

    Topics: Adrenergic beta-Agonists; Adult; Albuterol; Blood Pressure; Electromyography; Heart Rate; Humans; Is

1987

Other Studies

121 other studies available for albuterol and Muscle Relaxation

ArticleYear
Adrenerigic agents. 7.1 Synthesis and beta-adrenergic agonist activity of several 2-pyridylethanolamines.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Ethanolamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Musc

1977
Adrenergic agents. 8.1 Synthesis and beta-adrenergic agonist activity of some 3-tert-butylamino-2-(substituted phenyl)-1-propanols.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation;

1977
Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:11

    Topics: Amides; Animals; Benzopyrans; Bronchodilator Agents; Chemical Phenomena; Chemistry; Cromakalim; Guin

1990
Testosterone augments β
    Molecular and cellular endocrinology, 2020, 06-15, Volume: 510

    Topics: Albuterol; Animals; Cycloheximide; Dactinomycin; Genome; Guinea Pigs; Lung; Male; Muscle Cells; Musc

2020
An in vitro bioassay for evaluating the effect of inhaled bronchodilators on airway smooth muscle.
    Pulmonary pharmacology & therapeutics, 2020, Volume: 63

    Topics: Albuterol; Biological Assay; Bronchodilator Agents; Humans; Muscle Relaxation; Muscle, Smooth

2020
Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:1

    Topics: Adrenergic beta-2 Receptor Antagonists; Albuterol; Animals; Bronchodilator Agents; Carbamates; CHO C

2014
Gnaphaliin A and gnaphaliin B synergize the relaxant effect of salbutamol but not of ipratropium in guinea pig trachea.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:4

    Topics: Albuterol; Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Synergism; Flavono

2016
Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist.
    American journal of respiratory cell and molecular biology, 2016, Volume: 55, Issue:6

    Topics: Airway Remodeling; Albuterol; Animals; Bronchial Hyperreactivity; Bronchopulmonary Dysplasia; Diseas

2016
[Salbutamol improves diaphragmatic contractility in chronic airway obstruction].
    Archivos de bronconeumologia, 2009, Volume: 45, Issue:5

    Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Alkalosis; Animals; Chronic Disease; Diaphr

2009
Effects of formoterol on contraction and Ca2+ signaling of mouse airway smooth muscle cells.
    American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:3

    Topics: Albuterol; Animals; Calcium Signaling; Ethanolamines; Formoterol Fumarate; In Vitro Techniques; Intr

2010
Evidence that corticotropin-releasing hormone modulates myometrial contractility during human pregnancy.
    Endocrinology, 2009, Volume: 150, Issue:12

    Topics: Adult; Albuterol; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism;

2009
Budesonide prevents cytokine-induced decrease of the relaxant responses to formoterol and terbutaline, but not to salmeterol, in mouse trachea.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Bronchodilator Agents; Budesonide; Cyclic A

2010
Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis).
    Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:1

    Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Albuterol; Animals; Buffaloes; Cromakalim; Female; Glybur

2010
Nitric oxide is involved in the response of the isolated intact and epithelium-denuded rat trachea to the β₂ adrenergic receptor agonist salbutamol.
    Respiration; international review of thoracic diseases, 2010, Volume: 80, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Carbachol; Cholinergic Agonists; Electric S

2010
Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: a novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor.
    Bioorganic & medicinal chemistry letters, 2010, Oct-01, Volume: 20, Issue:19

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Binding Sites; Computer Simulation; Drug De

2010
Sex hormones modulate salbutamol-elicited long-term relaxation in isolated bovine tracheal strips.
    Pharmacology, 2011, Volume: 87, Issue:5-6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; Carba

2011
Characteristics of AZD9708, a novel, selective β2-adrenoceptor agonist with rapid onset and long duration of action.
    Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:4

    Topics: Adenosine Monophosphate; Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Asthma; Benzothiaz

2012
TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Aug-15, Volume: 303, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chloroquine; Humans; In Vitro Techniques; Isoprotereno

2012
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Dec-01, Volume: 303, Issue:11

    Topics: Albuterol; Animals; Bronchodilator Agents; Carbachol; Charybdotoxin; Chloroquine; Cholinergic Agonis

2012
Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:3

    Topics: Albuterol; Analysis of Variance; Animals; Atrial Natriuretic Factor; Bronchodilator Agents; Cattle;

2002
Muscarinic blockers potentiate beta-adrenergic relaxation of bovine iris sphincter.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2003, Volume: 241, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Dose-Response Relationship, Drug; Drug Synergi

2003
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
    Mediators of inflammation, 2003, Volume: 12, Issue:1

    Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female;

2003
Role of beta-adrenoceptor subtypes in mediating relaxation of the pig bladder trigonal muscle in vitro.
    Neurourology and urodynamics, 2003, Volume: 22, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dose-Response Relationshi

2003
QSAR and the rational design of long-acting dual D2-receptor/beta 2-adrenoceptor agonists.
    Journal of medicinal chemistry, 2003, Jul-17, Volume: 46, Issue:15

    Topics: Adrenergic beta-Agonists; Albuterol; Algorithms; Animals; Biological Transport; Dopamine Agonists; D

2003
The functional role of beta-adrenoceptor subtypes in mediating relaxation of pig urethral smooth muscle.
    The Journal of urology, 2003, Volume: 170, Issue:6 Pt 1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Ethanolamines; Female; Im

2003
cAMP-independent mechanism is significantly involved in beta2-adrenoceptor-mediated tracheal relaxation.
    European journal of pharmacology, 2004, May-10, Volume: 492, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonist

2004
Effect of 1,1-dimethylphenyl 1,4-piperazinium on mouse tracheal smooth muscle responsiveness.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:6

    Topics: Albuterol; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bronchoconstrictor Agents; Bronchodilat

2005
Adrenaline produces the relaxation of guinea-pig airway smooth muscle primarily through the mediation of beta(2)-adrenoceptors.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2005, Volume: 41, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dose-Response Relationshi

2005
Relaxant effects of beta-adrenergic agonists on porcine and human detrusor muscle.
    Acta physiologica Scandinavica, 2005, Volume: 185, Issue:2

    Topics: Adrenergic beta-Agonists; Aged; Albuterol; Animals; Dioxoles; Dose-Response Relationship, Drug; Epin

2005
Acetylcholine-induced aortic relaxation studied in salbutamol treated rats.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2005, Volume: 41, Issue:5

    Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Aorta, Thoracic; Cyclic AMP; Dose-Respo

2005
Effects of 138-355, a beta3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro.
    Neurourology and urodynamics, 2006, Volume: 25, Issue:7

    Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albutero

2006
Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; A

2007
Effect of an inhaled glucocorticoid on endothelial function in healthy smokers.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:1

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Androstadienes; Bronchodilator Agents; End

2008
Denervation and beta-adrenoreceptors of the cat nictitating membrane.
    Journal of autonomic pharmacology, 1981, Volume: 1, Issue:4

    Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Cats; Epinephrine; Female; In Vitro Techniques; Iso

1981
Desensitization of smooth muscle and mast cell beta-adrenoceptors in the airways of the guinea pig.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Clenbuterol; Dose-Response Relationship, Drug; Fenote

1984
Characterization of beta-adrenoceptors mediating relaxation of the guinea-pig ileum.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: Albuterol; Animals; Electric Stimulation; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Is

1984
Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 267, Issue:1

    Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Anaphylaxis; Animals; Cromolyn Sodium; Ethan

1984
Effect of bronchomotor tone on work rate of breathing.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:1

    Topics: Adult; Aerosols; Airway Resistance; Albuterol; Bronchi; Humans; Lung Compliance; Male; Methacholine

1984
Heterogeneous response patterns of aortae to norepinephrine.
    Artery, 1980, Volume: 7, Issue:2

    Topics: Albuterol; Animals; Aorta, Abdominal; Aorta, Thoracic; Epinephrine; Male; Muscle Contraction; Muscle

1980
Acute hyperoxic injury attenuates the relaxing effects of "loop" diuretics and salbutamol on large airways of newborn guinea pigs.
    Pediatric research, 1995, Volume: 38, Issue:3

    Topics: Albuterol; Animals; Animals, Newborn; Bronchi; Bronchodilator Agents; Diuretics; Ethacrynic Acid; Fe

1995
Role of K+ channel opening and Na(+)-K+ ATPase activity in airway relaxation induced by salbutamol.
    Life sciences, 1994, Volume: 55, Issue:11

    Topics: Albuterol; Analysis of Variance; Animals; Apamin; Bronchi; Charybdotoxin; Dogs; Dose-Response Relati

1994
The involvement of ATP-sensitive potassium channels in beta-adrenoceptor-mediated vasorelaxation in the rat isolated mesenteric arterial bed.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; B

1995
Inhibition of beta-adrenoceptor agonist relaxation of airway smooth muscle by Ca(2+)-activated K+ channel blockers.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Acetylcholine; Albuterol; Animals; Cadmium; Cadmium Chloride; Calcium; Calcium Channels; Charybdotox

1993
[Bronchial hyperresponsiveness and relaxability in patients with mitral stenosis].
    Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:11

    Topics: Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Met

1994
Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo.
    Respiration physiology, 1993, Volume: 94, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Clenbuterol; Diaphragm; Dogs; Dose-Res

1993
Cyclic nucleotide phosphodiesterase isoenzymes in guinea-pig tracheal muscle and bronchorelaxation by alkylxanthines.
    Biochemical pharmacology, 1994, Sep-15, Volume: 48, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Ag

1994
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:1

    Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; C

1993
Investigations into factors determining the duration of action of the beta 2-adrenoceptor agonist, salmeterol.
    British journal of pharmacology, 1993, Volume: 108, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Electric Stimulation; Gui

1993
Beta-adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Arginine; Colforsin; Cyclic AMP; Dobutamine; Endotheli

1993
Interaction of iberiotoxin with beta-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Drug Interactions; Guinea Pigs; In Vitro Techniques; I

1993
Salmeterol, formoterol, and salbutamol in the isolated guinea pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism.
    Thorax, 1993, Volume: 48, Issue:5

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanolam

1993
The effect of a novel benzopyran derivative, KC 399, on the isolated guinea-pig trachealis and human bronchi.
    General pharmacology, 1993, Volume: 24, Issue:6

    Topics: Albuterol; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Cromakalim; Guinea Pigs; Humans; In

1993
Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: Albuterol; Animals; Bronchi; Bronchodilator Agents; Cells, Cultured; Dinoprost; Electric Stimulation

1994
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In V

1993
Relaxant effects of pituitary adenylate cyclase activating polypeptide (PACAP) on epithelium-intact and -denuded guinea-pig trachea: a comparison with vasoactive intestinal peptide (VIP).
    Neuropeptides, 1995, Volume: 29, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Arginine; Bronchi; Cyclooxygenase Inhibitors; Epitheli

1995
Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies.
    Journal of pharmacological and toxicological methods, 1995, Volume: 34, Issue:2

    Topics: Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; Fem

1995
[Effects of the potassium channel activator cromakalim on human isolated bronchial smooth muscle].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1995, Volume: 18, Issue:3

    Topics: Adult; Albuterol; Benzopyrans; Bronchi; Bronchodilator Agents; Cromakalim; Drug Synergism; Female; H

1995
Correlation of cyclic AMP accumulation and relaxant actions of salmeterol and salbutamol in bovine tracheal smooth muscle.
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Cyclic AM

1995
Calcium mobilization and isometric tension in bovine tracheal smooth muscle: effects of salbutamol and histamine.
    Cell calcium, 1996, Volume: 19, Issue:1

    Topics: Albuterol; Aniline Compounds; Animals; Bronchodilator Agents; Calcium; Cattle; Colforsin; Electrophy

1996
Comparison of the profiles of agonists as stimulants of the beta 3-adrenoceptor in vitro with their gastroprotective effects in the conscious rat.
    British journal of pharmacology, 1996, Volume: 117, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Ag

1996
Effects of potassium-channel opener HOE 234 in guinea-pig airways.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:6

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Bronchodilator Agents; Chromans; Cyclooxygena

1996
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug S

1996
Extent of salmeterol-mediated reassertion of relaxation in guinea-pig trachea pretreated with aliphatic side chain structural analogues.
    British journal of pharmacology, 1996, Volume: 117, Issue:6

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Dose-Response Relationship, Dru

1996
Effect of pharmacological agonists on contractile responses in aortic rings derived from endotoxaemic rats.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:5

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Analysis of Variance;

1996
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adren

1996
A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea.
    Annals of the New York Academy of Sciences, 1996, Dec-26, Volume: 805

    Topics: Albuterol; Animals; Bronchodilator Agents; Captopril; Glycopeptides; Guinea Pigs; In Vitro Technique

1996
Kinetic studies of desensitization and resensitization of the relaxation response to beta-2 adrenoceptor agonists in isolated guinea pig trachea.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Guinea

1997
In vitro and in vivo effects of SCA40 on guinea pig airways.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: Albuterol; Animals; Blood Pressure; Bombesin; Bronchoconstriction; Bronchodilator Agents; Guinea Pig

1997
SCA 40: studies of the relaxant effects on cryopreserved human airway and vascular smooth muscle.
    British journal of pharmacology, 1997, Volume: 120, Issue:7

    Topics: Albuterol; Bronchi; Carbachol; Cryopreservation; Drug Interactions; Humans; Imidazoles; Muscle Relax

1997
Response of large and small vessels to alpha and beta adrenoceptor stimulation in heart failure: effect of angiotensin converting enzyme inhibition.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:3

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Angiotensin-Convertin

1997
Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Albuterol; Animals; Bronchi; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs

1997
Inhibitory effects of large Ca2+-activated K+ channel blockers on beta-adrenergic- and NO-donor-mediated relaxations of human and guinea-pig airway smooth muscles.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Animals; Benzimidazoles; Bronch

1998
A novel long-acting VIP analog in the guinea pig trachea in vitro.
    Peptides, 1998, Volume: 19, Issue:3

    Topics: Albuterol; Amino Acid Sequence; Animals; Captopril; Carbachol; Guinea Pigs; Male; Molecular Sequence

1998
The beta2- and beta3-adrenoceptor-mediated relaxation induced by isoprenaline and salbutamol in guinea pig taenia caecum.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1997, Volume: 33, Issue:3

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cecum; Dose-Respo

1997
Mechanisms of relaxations of bovine isolated bronchioles by the nitric oxide donor, GEA 3175.
    British journal of pharmacology, 1998, Volume: 123, Issue:5

    Topics: Albuterol; Aminoquinolines; Animals; Apamin; Bronchi; Bronchodilator Agents; Cattle; Charybdotoxin;

1998
Beta3-adrenergic relaxation of bovine iris sphincter.
    FEBS letters, 1998, Jun-16, Volume: 429, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bupranolol; Cattle; Colfo

1998
Atypical adrenoceptor-mediated relaxation of canine pulmonary artery through a cAMP-dependent pathway.
    Biochemical and biophysical research communications, 1998, Jul-30, Volume: 248, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cyclic AMP; Dioxoles; Dog

1998
A comparison between clenbuterol, salbutamol and terbutaline in relation to receptor binding and in vitro relaxation of equine tracheal muscle.
    Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:5

    Topics: Albuterol; Animals; Binding, Competitive; Bronchodilator Agents; Clenbuterol; Dose-Response Relation

1998
Effects of load and tone on the mechanics of isolated human bronchial smooth muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 86, Issue:2

    Topics: Albuterol; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Data Interpretation, Statistic

1999
Forskolin reverses tachyphylaxis to the bronchodilator effects of salbutamol: an in-vitro study on isolated guinea-pig trachea.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:2

    Topics: Albuterol; Animals; Bronchodilator Agents; Colforsin; Dose-Response Relationship, Drug; Drug Synergi

1999
Potentiation of cyclic AMP-mediated vasorelaxation by phenylephrine in pulmonary arteries of the rat.
    British journal of pharmacology, 1999, Volume: 127, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Colforsin

1999
Is beta-adrenergic-mediated airway relaxation of salmeterol antagonized by its solvent xinafoic acid?
    Chest, 1999, Volume: 115, Issue:6

    Topics: Administration, Inhalation; Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronch

1999
Cross-desensitization to furosemide and salbutamol in isolated neonatal guinea pig airways.
    Biology of the neonate, 1999, Volume: 76, Issue:2

    Topics: Acetylcholine; Albuterol; Animals; Animals, Newborn; Bronchodilator Agents; Cyclic AMP; Drug Toleran

1999
Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol.
    Biochemistry, 1999, Aug-31, Volume: 38, Issue:35

    Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Albu

1999
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
    European journal of pharmacology, 1999, Nov-26, Volume: 385, Issue:1

    Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibi

1999
Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle.
    European journal of pharmacology, 2000, Feb-11, Volume: 389, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Amides; Animals; Bronchoconstrictor Agents; Bronchodilator Agen

2000
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:10

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

1993
Lidocaine potentiates the relaxant effects of cAMP-elevating agents in bovine tracheal smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Anesthetics, Local; Animals; Bupivacaine; Cattle; Colforsin;

2000
Involvement of K(+) channel in procainamide-induced relaxation of bovine tracheal smooth muscle.
    European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2

    Topics: Albuterol; Animals; Anti-Arrhythmia Agents; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle

2000
Functional, biochemical and molecular biological evidence for a possible beta(3)-adrenoceptor in human near-term myometrium.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol; Cyclic AMP; Cyclic GMP; Dos

2000
Functional properties of atypical beta-adrenoceptors on the guinea pig duodenum.
    European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprenolol; Animals; Bupranolol; C

2001
Mexiletine inhibits pharmacological actions of salbutamol through blockade of beta2-adrenoceptors in bovine tracheal smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:5

    Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Anti-Arrhythmia Agents; Bronchodilator Agents; Catt

2001
Bronchodilating properties of the VIP receptor agonist Ro 25-1553 compared to those of formoterol on the guinea-pig isolated trachea.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Albuterol; Amino Acid Sequence; Animals; Bronchodilator Agents; Carbachol; Dose-Response Relationshi

2001
The role of beta(3)-adrenoceptors in mediating relaxation of porcine detrusor muscle.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Binding, Competitive; Dos

2002
Pharmacologically induced relaxation of tracheal smooth muscle is increased in hyperoxia-exposed 15-day-old rats.
    Pediatric pulmonology, 2002, Volume: 33, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Animals, Newborn; Hyperoxia; Muscle Relaxation; Muscle

2002
The beta-adrenoceptors responsible for a direct relaxation of the uncontracted nictitating membrane of the anaesthetized cat.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 226, Issue:2

    Topics: Albuterol; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Isop

1977
Role of cyclic AMP in adrenergically induced tracheal smooth muscle relaxation.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Albuterol; Animals; Cattle; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Muscle Cont

1977
Effect of ACTH on the relaxation of guinea pig trachea with various bronchodilators.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:8

    Topics: Adrenocorticotropic Hormone; Airway Resistance; Albuterol; Aminophylline; Animals; Bronchodilator Ag

1978
One way cross tolerance between cromakalim and salbutamol in the uterus of the rat in vivo.
    British journal of pharmacology, 1992, Volume: 105, Issue:1

    Topics: Albuterol; Animals; Benzopyrans; Cromakalim; Cyclic AMP; Drug Interactions; Drug Tolerance; Female;

1992
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascu

1992
Methylprednisolone restores sensitivity to beta-adrenergic agonists in Basenji-Greyhound dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:2

    Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Aminophylline; Animals; Dogs; Drug Resistanc

1992
Relaxation of soman-induced contracture of airway smooth muscle in vitro.
    Drug and chemical toxicology, 1992, Volume: 15, Issue:3

    Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Colforsin; Dogs; Dose-Response Relation

1992
Studies on the interaction between formoterol and salmeterol in guinea-pig trachea in vitro.
    Pharmacology & toxicology, 1992, Volume: 71, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Drug Interactions; Electric Sti

1992
Effect of lithium on gastro-intestinal complications in alloxan-diabetic rats.
    General pharmacology, 1992, Volume: 23, Issue:4

    Topics: Albuterol; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Duodenum; Gastrointestinal Disea

1992
Effect of Rb+ on cromakalim-induced relaxation and ion fluxes in guinea pig trachea.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Albuterol; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Guinea Pigs; In Vitro Techniques

1992
Classification of postjunctional beta adrenoceptors mediating relaxation of canine bronchi.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Calcium; Carbachol; Dogs; Electric Stimulatio

1991
Salmeterol, a novel, long-acting beta 2-adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Dinoprost; Electric Stimulation

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Beta-adrenoceptor profile of ractopamine HCl in isolated smooth and cardiac muscle tissues of rat and guinea-pig.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:12

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Female; Guinea Pigs; Heart; In Vitro Techniques; Isopr

1991
Role of the epithelium in airway smooth muscle responses to relaxant agonists.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:4

    Topics: Albuterol; Animals; Arachidonic Acid; Bronchodilator Agents; Diffusion; Epithelium; Guinea Pigs; In

1991
Evaluation of the potassium channel activator BRL 38227 as an inhaled bronchodilator in the guinea-pig: contrast with nifedipine and salbutamol.
    Pulmonary pharmacology, 1991, Volume: 4, Issue:2

    Topics: Administration, Inhalation; Airway Resistance; Albuterol; Aminophylline; Animals; Benzopyrans; Bronc

1991
The role of the epithelium in modulating the responses of guinea-pig trachea induced by bradykinin in vitro.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bradyk

1990
Effects of extracellular acidosis on the action of smooth muscle relaxants.
    Proceedings of the Western Pharmacology Society, 1990, Volume: 33

    Topics: Acidosis; Albuterol; Amiloride; Animals; Carbachol; Dogs; In Vitro Techniques; Isometric Contraction

1990
Relaxations of guinea-pig isolated trachea induced by platelet-activating factor are epithelial-dependent and are antagonised by WEB 2086.
    European journal of pharmacology, 1990, Sep-21, Volume: 186, Issue:2-3

    Topics: Albuterol; Animals; Azepines; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Musc

1990
Evaluation of the bronchodilator properties of Ro 31-6930, a novel potassium channel opener, in the guinea-pig.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: Albuterol; Anesthesia; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Decerebrate State; D

1990
Effect of coenzyme Q10, a quinone derivative, on guinea pig lung and tracheal tissue.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:6

    Topics: Albuterol; Animals; Coenzymes; Dinoprost; Dinoprostone; Guinea Pigs; Histamine Release; In Vitro Tec

1985
Isoproterenol- and salbutamol-induced relaxation of acetylcholine- and histamine-induced contraction of equine trachealis muscle in vitro.
    American journal of veterinary research, 1989, Volume: 50, Issue:10

    Topics: Acetylcholine; Albuterol; Analysis of Variance; Animals; Culture Techniques; Histamine; Horses; Isop

1989
The effect of varying carbachol concentration on the slope of Schild plots of selective beta-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:2

    Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Carbachol; Guinea Pigs; In Vitro Techniqu

1986
Enhanced relaxation response of canine coronary artery to isoproterenol and salbutamol after removal of endothelial cells.
    General pharmacology, 1986, Volume: 17, Issue:4

    Topics: Acetylcholine; Albuterol; Animals; Coronary Vessels; Dogs; Endothelium; In Vitro Techniques; Isoprot

1986
Comparison of VIP and beta 2-adrenoceptor-induced relaxations in the circular and longitudinal smooth muscle layers of the rat portal vein.
    Acta physiologica Scandinavica, 1987, Volume: 130, Issue:4

    Topics: Albuterol; Animals; Apamin; Female; Isoproterenol; Methoxamine; Muscle Contraction; Muscle Relaxatio

1987
Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro.
    The American review of respiratory disease, 1985, Volume: 132, Issue:1

    Topics: Aged; Albuterol; Bronchi; Bronchial Provocation Tests; Colforsin; Diterpenes; Female; Forced Expirat

1985