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albuterol and Hypercapnia

albuterol has been researched along with Hypercapnia in 13 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"5 mg) albuterol (salbutamol) over 1 h in 47 patients admitted to hospital with severe acute asthma defined as a peak expiratory flow (PEF) below 150 L/min and hypercapnia (Pa(CO2) > or = 40 mm Hg)."9.07Nebulized versus intravenous albuterol in hypercapnic acute asthma. A multicenter, double-blind, randomized study. ( Brochard, L; Duroux, P; Henry-Amar, M; Mal, H; Renon, D; Salmeron, S; Simonneau, G; Tenaillon, A, 1994)
"Under stable conditions most subjects with severe COPD and hypercapnia will have a fall in P(a)CO(2) and P(a)O(2) following 10 mg rac-albuterol, suggesting that they maintain capacity to respond to any increase in VCO(2) and prevent a rise in P(a)CO(2)."5.12Effects of rac-albuterol on arterial blood gases in patients with stable hypercapnic chronic obstructive pulmonary disease. ( Cooper, S; Harrison, TW; Mortimer, K; Oborne, J; Sovani, MP; Tattersfield, AE; Whale, CI, 2006)
"5 mg) albuterol (salbutamol) over 1 h in 47 patients admitted to hospital with severe acute asthma defined as a peak expiratory flow (PEF) below 150 L/min and hypercapnia (Pa(CO2) > or = 40 mm Hg)."5.07Nebulized versus intravenous albuterol in hypercapnic acute asthma. A multicenter, double-blind, randomized study. ( Brochard, L; Duroux, P; Henry-Amar, M; Mal, H; Renon, D; Salmeron, S; Simonneau, G; Tenaillon, A, 1994)
"The goal of management of patients with respiratory failure is to restore them to a state of quiet breathing, without complication."2.41Management of respiratory failure in patients with asthma. ( Corbridge, T; Gluckman, TJ, 2000)
" Therefore, we infused salbutamol at a higher dosage (23."1.35Effect of salbutamol on respiratory muscle function and ventilation in awake canines. ( Easton, PA; Holroyde, MC; Johnson, MW; Katagiri, M; Kusuhara, N; Rothwell, BC, 2008)
" Given via the trachea, salbutamol bioavailability was decreased by hypoxia."1.29Influence of hypoxia and hypercapnia on the kinetics and hypokaliaemic effect of salbutamol in the rabbit. ( Du Souich, P; Ong, H; Perreault, S; Saunier, C, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's2 (15.38)18.2507
2000's9 (69.23)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, J1
Cui, Z1
Liu, S1
Gao, X1
Gao, P1
Shi, Y1
Guo, S1
Li, P1
Richie, RC1
Angulo, M1
Taranto, E1
Soto, JP1
Malacrida, L1
Nin, N1
Hurtado, FJ1
Píriz, H1
Gunkel, CI1
Valverde, A1
Robertson, SA1
Thompson, MS1
Keoughan, CG1
Ferrell, EA1
Mazzeo, AT1
Spada, A1
Praticò, C1
Lucanto, T1
Santamaria, LB1
Xu, X1
Zhou, J1
Yang, Q1
Fang, L1
Xie, Q1
Shen, Y1
Udy, A1
Whale, CI1
Sovani, MP1
Mortimer, K1
Oborne, J1
Cooper, S1
Harrison, TW1
Tattersfield, AE1
Easton, PA1
Katagiri, M1
Johnson, MW1
Rothwell, BC1
Holroyde, MC1
Kusuhara, N1
Perreault, S1
Saunier, C1
Ong, H1
Du Souich, P1
Salmeron, S1
Brochard, L1
Mal, H1
Tenaillon, A1
Henry-Amar, M1
Renon, D1
Duroux, P1
Simonneau, G1
Gluckman, TJ1
Corbridge, T1
Lim, TK1
Tan, WC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pulmonary Gas Exchange Response to Indacaterol in Stable Symptomatic Chronic Obstructive Pulmonary Disease Patients[NCT02547558]Phase 420 participants (Anticipated)Interventional2015-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for albuterol and Hypercapnia

ArticleYear
Management of respiratory failure in patients with asthma.
    Current opinion in pulmonary medicine, 2000, Volume: 6, Issue:1

    Topics: Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Calcium Channel Blockers; Gluc

2000

Trials

2 trials available for albuterol and Hypercapnia

ArticleYear
Effects of rac-albuterol on arterial blood gases in patients with stable hypercapnic chronic obstructive pulmonary disease.
    British journal of clinical pharmacology, 2006, Volume: 62, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Area Under Curve; Bronchodilato

2006
Nebulized versus intravenous albuterol in hypercapnic acute asthma. A multicenter, double-blind, randomized study.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:6

    Topics: Acute Disease; Administration, Inhalation; Adolescent; Adult; Aged; Albuterol; Analysis of Variance;

1994

Other Studies

10 other studies available for albuterol and Hypercapnia

ArticleYear
Early use of noninvasive techniques for clearing respiratory secretions during noninvasive positive-pressure ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease and hypercapnic encephalopathy: A prospective cohort stud
    Medicine, 2017, Volume: 96, Issue:12

    Topics: Aged; Albuterol; Ambroxol; Brain Diseases; Equipment Design; Feasibility Studies; Female; Humans; Hy

2017
Assessing mortality risk in COPD.
    Journal of insurance medicine (New York, N.Y.), 2008, Volume: 40, Issue:1

    Topics: Actuarial Analysis; Albuterol; Androstadienes; Body Mass Index; Bronchial Hyperreactivity; Bronchodi

2008
[Salbutamol improves diaphragmatic contractility in chronic airway obstruction].
    Archivos de bronconeumologia, 2009, Volume: 45, Issue:5

    Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Alkalosis; Animals; Chronic Disease; Diaphr

2009
Treatment for a severe reaction to intravenous administration of diatrizoate in an anesthetized horse.
    Journal of the American Veterinary Medical Association, 2004, Apr-01, Volume: 224, Issue:7

    Topics: Aerosols; Albuterol; Anesthesia; Animals; Bronchoconstriction; Bronchodilator Agents; Contrast Media

2004
Hypercapnia: what is the limit in paediatric patients? A case of near-fatal asthma successfully treated by multipharmacological approach.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:7

    Topics: Acidosis, Respiratory; Albuterol; Asthma; Bronchodilator Agents; Child; Drug Therapy, Combination; G

2004
An in vitro rat diaphragmatic fatigue model induced by combined hypoxic and hypercapnic acidosis and the effect of salmeterol.
    Pharmacological research, 2006, Volume: 53, Issue:2

    Topics: Acidosis; Adrenergic beta-Agonists; Albuterol; Aminophylline; Animals; Bronchodilator Agents; Diaphr

2006
A 10-year-old child with status asthmaticus, hypercapnia and a unilateral dilated pupil.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:12

    Topics: Albuterol; Bronchodilator Agents; Child; Humans; Hypercapnia; Ipratropium; Male; Mydriasis; Nebulize

2005
Effect of salbutamol on respiratory muscle function and ventilation in awake canines.
    Respiratory physiology & neurobiology, 2008, May-31, Volume: 161, Issue:3

    Topics: Albuterol; Animals; Bronchodilator Agents; Dogs; Dose-Response Relationship, Drug; Electromyography;

2008
Influence of hypoxia and hypercapnia on the kinetics and hypokaliaemic effect of salbutamol in the rabbit.
    Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:3

    Topics: Administration, Oral; Albuterol; Animals; Half-Life; Hypercapnia; Hypoxia; Infusions, Intravenous; K

1995
Acute carbon dioxide narcosis during inhalational therapy with oxygen powered nebulizers in patients with chronic airflow limitation.
    Annals of the Academy of Medicine, Singapore, 1985, Volume: 14, Issue:3

    Topics: Aerosols; Aged; Albuterol; Female; Humans; Hypercapnia; Lung Diseases, Obstructive; Male; Middle Age

1985