Page last updated: 2024-10-22

albuterol and Hay Fever

albuterol has been researched along with Hay Fever in 24 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Research Excerpts

ExcerptRelevanceReference
"Safety and efficacy of desloratadine and montelukast each were assessed in a double-blind, placebo-controlled trial of patients with SAR and symptoms of asthma, who were assigned randomly to once-daily treatment with desloratadine 5 mg, montelukast 10 mg, or placebo for 4 weeks."9.10Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma. ( Baena-Cagnani, CE; Berger, WE; Danzig, M; DuBuske, LM; Gurné, SE; Lorber, R; Stryszak, P, 2003)
"This study explored the safety and efficacy of cetirizine for treatment of allergic rhinitis and asthma."9.08Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial. ( Findlay, SR; Glovsky, MM; Grant, JA; Grossman, J; Kaiser, H; Meltzer, EO; Mitchell, DQ; Nicodemus, CF; Pearlman, D; Selner, J, 1995)
"We sought to determine the efficacy and safety of loratadine (5 mg) plus pseudoephedrine (120 mg) (L/P) twice daily in patients with seasonal allergic rhinitis and mild asthma."9.08Efficacy and safety of loratadine plus pseudoephedrine in patients with seasonal allergic rhinitis and mild asthma. ( Aaronson, D; Beaucher, W; Berkowitz, R; Bronsky, E; Chen, R; Chervinsky, P; Cohen, R; Corren, J; Fourre, J; Grossman, J; Harris, AG; Meltzer, E; Pedinoff, A; Stricker, W; Wanderer, A, 1997)
"Allergen-induced sneeze, postnasal drip and nasal obstruction were significantly reduced by fluticasone, but not by salmeterol."5.12Effects of intranasal fluticasone and salmeterol on allergen-induced nasal responses. ( Fanat, A; O'Byrne, PM; Parameswaran, K, 2006)
"AMP nasal provocation produced considerable sneezing and induced a transient increase in histamine and tryptase release with peak values achieved at 3 min after the challenge in all the subjects studied."5.11Effect of salbutamol on nasal symptoms and mast cell degranulation induced by adenosine 5' monophosphate nasal challenge. ( Guarino, F; Polosa, R; Prosperini, G; Russo, C; Spicuzza, L; Zeng, D, 2005)
"Safety and efficacy of desloratadine and montelukast each were assessed in a double-blind, placebo-controlled trial of patients with SAR and symptoms of asthma, who were assigned randomly to once-daily treatment with desloratadine 5 mg, montelukast 10 mg, or placebo for 4 weeks."5.10Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma. ( Baena-Cagnani, CE; Berger, WE; Danzig, M; DuBuske, LM; Gurné, SE; Lorber, R; Stryszak, P, 2003)
"This study explored the safety and efficacy of cetirizine for treatment of allergic rhinitis and asthma."5.08Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial. ( Findlay, SR; Glovsky, MM; Grant, JA; Grossman, J; Kaiser, H; Meltzer, EO; Mitchell, DQ; Nicodemus, CF; Pearlman, D; Selner, J, 1995)
"We sought to determine the efficacy and safety of loratadine (5 mg) plus pseudoephedrine (120 mg) (L/P) twice daily in patients with seasonal allergic rhinitis and mild asthma."5.08Efficacy and safety of loratadine plus pseudoephedrine in patients with seasonal allergic rhinitis and mild asthma. ( Aaronson, D; Beaucher, W; Berkowitz, R; Bronsky, E; Chen, R; Chervinsky, P; Cohen, R; Corren, J; Fourre, J; Grossman, J; Harris, AG; Meltzer, E; Pedinoff, A; Stricker, W; Wanderer, A, 1997)
"Desloratadine is a potent antihistamine."2.73The effect of regular versus on-demand desloratadine treatment in children with allergic rhinitis. ( Adalioglu, G; Dizdar, EA; Dogan, C; Kalayci, O; Keskin, O; Sekerel, BE; Tuncer, A, 2007)
"Blisters were induced, two on each forearm, by gentle suction and heating, and were unroofed 12 h later, after which plastic chambers were placed over the denuded area."2.68Effects of salmeterol and terbutaline on IgE-mediated dermal reactions and inflammatory events in skin chambers in atopic patients. ( Grönneberg, R; Halldén, G; Hed, J; Raud, J; van Hage-Hamsten, M, 1996)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.83)18.7374
1990's8 (33.33)18.2507
2000's10 (41.67)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ramos, MI1
Cubillas, JJ1
Feito, FR1
Prieto, L1
Gutiérrez, V1
Torres, V1
Uixera, S1
Marín, J1
Baena-Cagnani, CE1
Berger, WE1
DuBuske, LM1
Gurné, SE1
Stryszak, P1
Lorber, R1
Danzig, M1
Marogna, M1
Falagiani, P1
Bruno, M1
Massolo, A1
Riva, G1
Asero, R1
Russo, C1
Zeng, D1
Prosperini, G1
Spicuzza, L1
Guarino, F1
Polosa, R1
Parameswaran, K1
Fanat, A1
O'Byrne, PM1
Dizdar, EA1
Sekerel, BE1
Keskin, O1
Kalayci, O1
Adalioglu, G1
Dogan, C1
Tuncer, A1
Kupczyk, M1
Bogacka, E1
Bocheńska-Marciniak, M1
Sterchaluk-Grzyb, E1
Tworek, D1
Kuna, P1
González de Olano, D1
Trujillo Trujillo, MJ1
Santos Magadán, S1
Menéndez-Baltanás, A1
Gandolfo Cano, M1
Ariz Muñoz, S1
Sanz Larruga, ML1
González-Mancebo, E1
Ind, PW1
Miyatake, A1
Brown, MJ1
Dollery, CT1
Svenonius, E1
Arborelius, M1
Kautto, R1
Lilja, B1
Grant, JA1
Nicodemus, CF1
Findlay, SR1
Glovsky, MM1
Grossman, J2
Kaiser, H1
Meltzer, EO1
Mitchell, DQ1
Pearlman, D1
Selner, J1
Di Lorenzo, G1
Morici, G1
Norrito, F1
Mansueto, P1
Melluso, M1
Purello D'Ambrosio, F1
Barbagallo Sangiorgi, G1
O'Connor, J1
Kane, GC1
Tolino, M1
Pollice, M1
Fish, JE2
Peters, SP2
Grönneberg, R1
van Hage-Hamsten, M1
Halldén, G1
Hed, J1
Raud, J1
Hastie, AT1
Everts, KB1
Shaver, JR1
Cirelli, R1
Zangrilli, J1
Pollice, MB1
Leff, AR1
Herrnreiter, A1
Naclerio, RM1
Baroody, FM1
Handley, DA1
Muñoz, NM1
Corren, J1
Harris, AG1
Aaronson, D1
Beaucher, W1
Berkowitz, R1
Bronsky, E1
Chen, R1
Chervinsky, P1
Cohen, R1
Fourre, J1
Meltzer, E1
Pedinoff, A1
Stricker, W1
Wanderer, A1
Proud, D1
Reynolds, CJ1
Lichtenstein, LM1
Kagey-Sobotka, A1
Togias, A1
Cohn, JR1
Sataloff, RT1
Branton, C1
Lidington, RE1
Cotton, DJ1
Graham, BL1
Dosman, JA1
Jorde, W1
Bohlmann, HG1
Linsenmann, P1
Werdermann, K1
Vignale, L1
Parentini, GC1
Rossi, PC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic Rhinitis[NCT00119015]Phase 4102 participants (Actual)Interventional2005-07-31Terminated (stopped due to Difficulty in recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Other Symptom Score Over 2 Week Randomized Treatment Period

"Patients recorded the severity of other symptoms, including itchy nose/eyes and post-nasal drip, twice a day on a scale from 0 to 3 (0 = no symptoms, 1 = mild, 2 = moderate, and 3 = severe). The other symptom score was calculated as the sum of all scores for morning and evening recordings with a range of 0 to 6.~The baseline symptom score used in the analysis was the average of the symptom scores from the last 5 days of fluticasone propionate therapy prior to randomized treatment period.~The change from baseline for each subsequent day of treatment was then calculated for each subject. So that each subject only had one observation, the average of these changes was calculated for each subject, and this summary measure was used in the analysis comparing the two treatment groups. We report the median and full range of these average changes for each group.~A negative value indicates an improvement in symptoms." (NCT00119015)
Timeframe: Baseline and 2 weeks

Interventionunits on a scale (Median)
Fluticasone Propionate + Montelukast-0.24
Fluticasone Propionate + Placebo-0.14

Change From Baseline in Runny Nose Symptom Score Over 2 Week Randomized Treatment Period

"Patients recorded the severity of runny nose twice a day on a scale from 0 to 3 (0 = no symptoms, 1 = mild, 2 = moderate, and 3 = severe). The runny nose symptom score was calculated as the sum of all scores for morning and evening recordings with a range of 0 to 6.~The baseline symptom score used in the analysis was the average of the symptom scores from the last 5 days of fluticasone propionate therapy prior to randomized treatment period.~The change from baseline for each subsequent day of treatment was then calculated for each subject. So that each subject only had one observation, the average of these changes was calculated for each subject, and this summary measure was used in the analysis comparing the two treatment groups. We report the median and full range of these average changes for each group.~A negative value indicates an improvement in symptoms." (NCT00119015)
Timeframe: Baseline and 2 weeks

Interventionunits on a scale (Median)
Fluticasone Propionate + Montelukast-0.52
Fluticasone Propionate + Placebo-0.29

Change From Baseline in Sneezing Symptom Score Over 2 Week Randomized Treatment Period

"Patients recorded the severity of sneezing twice a day on a scale from 0 to 3 (0 = no symptoms, 1 = mild, 2 = moderate, and 3 = severe). The sneezing symptom score was calculated as the sum of all scores for morning and evening recordings with a range of 0 to 6.~The baseline symptom score used in the analysis was the average of the symptom scores from the last 5 days of fluticasone propionate therapy prior to randomized treatment period.~The change from baseline for each subsequent day of treatment was then calculated for each subject. So that each subject only had one observation, the average of these changes was calculated for each subject, and this summary measure was used in the analysis comparing the two treatment groups. We report the median and full range of these average changes for each group.~A negative value indicates an improvement in symptoms." (NCT00119015)
Timeframe: Baseline and 2 weeks

Interventionunits on a scale (Median)
Fluticasone Propionate + Montelukast-0.22
Fluticasone Propionate + Placebo-0.25

Change From Baseline in Stuffy Nose Symptom Score Over 2 Week Randomized Treatment Period

"Patients recorded the severity of stuffy nose twice a day on a scale from 0 to 3 (0 = no symptoms, 1 = mild, 2 = moderate, and 3 = severe). The stuffy nose symptom score was calculated as the sum of all scores for morning and evening recordings with a range of 0 to 6.~The baseline symptom score used in the analysis was the average of the symptom scores from the last 5 days of fluticasone propionate therapy prior to randomized treatment period.~The change from baseline for each subsequent day of treatment was then calculated for each subject. So that each subject only had one observation, the average of these changes was calculated for each subject, and this summary measure was used in the analysis comparing the two treatment groups. We report the median and full range of these average changes for each group.~A negative value indicates an improvement in symptoms." (NCT00119015)
Timeframe: Baseline and 2 weeks

Interventionunits on a scale (Median)
Fluticasone Propionate + Montelukast-0.41
Fluticasone Propionate + Placebo-0.47

Change From Baseline in Total Nasal Symptom Score (TNSS) Over 2 Week Randomized Treatment Period

"Patients recorded the severity of sneezing, runny nose, stuffy nose, and other symptoms (itchy nose/eyes and post-nasal drip) twice a day on a scale from 0 to 3 (0 = no symptoms, 1 = mild, 2 = moderate, and 3 = severe). The TNSS was calculated as the sum of all scores for morning and evening recordings with a range of 0 to 24.~The baseline TNSS used in the analysis was the average of the symptom scores from the last 5 days of fluticasone propionate therapy prior to randomized treatment period.~The change from baseline for each subsequent day of treatment was then calculated for each subject. So that each subject only had one observation, the average of these changes was calculated for each subject, and this summary measure was used in the analysis comparing the two treatment groups. We report the median and full range of these average changes for each group.~A negative value indicates an improvement in symptoms." (NCT00119015)
Timeframe: Baseline and 2 weeks

Interventionunits on a scale (Median)
Fluticasone Propionate + Montelukast-1.66
Fluticasone Propionate + Placebo-2.21

Trials

11 trials available for albuterol and Hay Fever

ArticleYear
Effect of salmeterol on seasonal changes in airway responsiveness and exhaled nitric oxide in pollen-sensitive asthmatic subjects.
    Chest, 2002, Volume: 122, Issue:3

    Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Airway Resistance; Albuterol

2002
Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma.
    International archives of allergy and immunology, 2003, Volume: 130, Issue:4

    Topics: Acetates; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Anti-Asthmatic Agents; Asthm

2003
Effect of salbutamol on nasal symptoms and mast cell degranulation induced by adenosine 5' monophosphate nasal challenge.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:9

    Topics: Adenosine Monophosphate; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Anti-Inflammatory A

2005
Effects of intranasal fluticasone and salmeterol on allergen-induced nasal responses.
    Allergy, 2006, Volume: 61, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Androstadienes; Anti-Allergi

2006
The effect of regular versus on-demand desloratadine treatment in children with allergic rhinitis.
    International journal of pediatric otorhinolaryngology, 2007, Volume: 71, Issue:6

    Topics: Adolescent; Albuterol; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents;

2007
[The effect of desloratadine on use of rescue beta2-agonists and symptoms in patients suffering from seasonal allergic rhinitis and asthma].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2005, Volume: 18, Issue:104

    Topics: Administration, Oral; Adult; Albuterol; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Broncho

2005
Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial.
    The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:5 Pt 1

    Topics: Adolescent; Adult; Albuterol; Asthma; Cetirizine; Double-Blind Method; Ephedrine; Humans; Male; Plac

1995
Comparison of the effects of salmeterol and salbutamol on clinical activity and eosinophil cationic protein serum levels during the pollen season in atopic asthmatics.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:10

    Topics: Adult; Albuterol; Asthma; Blood Proteins; Cell Count; Cross-Over Studies; Eosinophil Granule Protein

1995
Effects of salmeterol and terbutaline on IgE-mediated dermal reactions and inflammatory events in skin chambers in atopic patients.
    Allergy, 1996, Volume: 51, Issue:9

    Topics: Administration, Cutaneous; Adrenergic beta-Agonists; Adult; Albuterol; Blister; Dermatitis, Atopic;

1996
Efficacy and safety of loratadine plus pseudoephedrine in patients with seasonal allergic rhinitis and mild asthma.
    The Journal of allergy and clinical immunology, 1997, Volume: 100, Issue:6 Pt 1

    Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Child; Double-Blind Method; Drug Therapy, Combination; E

1997
Intranasal salmeterol inhibits allergen-induced vascular permeability but not mast cell activation or cellular infiltration.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1998, Volume: 28, Issue:7

    Topics: Administration, Intranasal; Adrenergic beta-Agonists; Albuterol; Asthma; Capillary Permeability; Cel

1998

Other Studies

13 other studies available for albuterol and Hay Fever

ArticleYear
Improvement of the Prediction of Drugs Demand Using Spatial Data Mining Tools.
    Journal of medical systems, 2016, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Bronchodilator Agents; Child; Child, Preschoo

2016
The allergic march in pollinosis: natural history and therapeutic implications.
    International archives of allergy and immunology, 2004, Volume: 135, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Child; Coho

2004
Efficacy of injection immunotherapy with ragweed and birch pollen in elderly patients.
    International archives of allergy and immunology, 2004, Volume: 135, Issue:4

    Topics: Adult; Age Factors; Aged; Albuterol; Allergens; Ambrosia; Asthma; Betula; Bronchodilator Agents; Fem

2004
Anaphylaxis to salbutamol.
    Journal of investigational allergology & clinical immunology, 2008, Volume: 18, Issue:2

    Topics: Adult; Albuterol; Anaphylaxis; Drug Hypersensitivity; Erythema; Female; Humans; Immunoglobulin E; Rh

2008
Do human mast cells possess functional beta adrenoceptors in vivo?
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Adult; Albuterol; Asthma; Female; Histamine; Histamine Release; Humans; Male; Mast Cells; Propranolo

1983
Lung function studies in children with allergic rhinitis.
    Allergy, 1982, Volume: 37, Issue:2

    Topics: Adolescent; Albuterol; Child; Exercise Test; Functional Residual Capacity; Humans; Maximal Midexpira

1982
Inhaled albuterol does not inhibit cellular influx or lung injury produced by segmental antigen challenge in humans.
    Pulmonary pharmacology, 1995, Volume: 8, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Antigens; Asthma; Bronchial

1995
Beta 2-agonist-elevated stress response in human bronchial epithelial cells in vivo and in vitro.
    Lung, 1997, Volume: 175, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Albuterol; Allergens; Asthma; Biopsy; Bronchi; Bronchial Provocatio

1997
Effect of enantiomeric forms of albuterol on stimulated secretion of granular protein from human eosinophils.
    Pulmonary pharmacology & therapeutics, 1997, Volume: 10, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Eosinophil Peroxidase; Eosinophils; Humans; Immunoglobulin E; N

1997
Response of asthma-related voice dysfunction to allergen immunotherapy: a case report of confirmation by methacholine challenge.
    Journal of voice : official journal of the Voice Foundation, 2001, Volume: 15, Issue:4

    Topics: Adult; Albuterol; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Desensitization, Immunol

2001
Peripheral airways obstruction in patients with rhinitis.
    Annals of allergy, 1979, Volume: 42, Issue:1

    Topics: Adult; Airway Obstruction; Albuterol; Female; Forced Expiratory Volume; Humans; Male; Maximal Midexp

1979
[Protective effect of beta-adrenergic substances on the allergic rhinitis (author's transl)].
    Medizinische Klinik, 1975, Aug-08, Volume: 70, Issue:32-33

    Topics: Airway Resistance; Albuterol; Humans; Metaproterenol; Phenols; Rhinitis, Allergic, Seasonal; Time Fa

1975
[Evaluation of the bronchial tonus, basal and following bronchodilators, in subjects with allergic rhinitis].
    Minerva medica, 1989, Volume: 80, Issue:5

    Topics: Adolescent; Adult; Albuterol; Bronchi; Bronchodilator Agents; Female; Forced Expiratory Volume; Huma

1989