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albuterol and Drug Overdose

albuterol has been researched along with Drug Overdose in 19 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"Presenting a case of acute theophylline and salbutamol overdose with distributive shock."7.96Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose. ( Chandrasekaran, VP; Muruga, B; Parthasarathy, A, 2020)
" Laboratory findings showed hypokalemia, hypophosphatemia, and lactic acidosis."7.78Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. ( Hantson, P; Manara, A; Thys, F; Vanpee, D, 2012)
"Albuterol overdose can lead to tachycardia, hypotension, tremor, hypokalemia, and hyperglycemia in children."7.72Hypoglycemia after albuterol overdose in a pediatric patient. ( Duman, M; Ozdemir, D; Tuncok, Y; Unal, N; Yilmaz, E, 2004)
"The cases of two asthmatic adolescents who overdosed on albuterol are presented."7.68Propranolol treatment of albuterol poisoning in two asthmatic patients. ( Henretig, F; Joffe, M; Ramoska, EA; Spiller, HA, 1993)
" Although transient, the dose-response relationship and duration of effect is unknown."5.29Hypokalemia after pediatric albuterol overdose: a case series. ( Leikin, JB; Linowiecki, KA; Paloucek, F; Soglin, DF, 1994)
"Hypoglycemia has previously been reported in newborns of mothers following prolonged use of sympathomimetics used as tocolytic therapy."5.28Hypoglycemia following albuterol overdose in a child. ( Amitai, Y; Wasserman, D, 1992)
"1) Mean weekly inhaled steroid adherence [(number of actuations/prescribed number of actuations) x 100]; 2) number of days with overuse of inhaled steroids; 3) 24-hour and nighttime albuterol use; 4) included forced expiratory volume in 1 second; and 5) Asthma Quality of Life Questionnaire total score."5.10Direct clinician-to-patient feedback discussion of inhaled steroid use: its effect on adherence. ( Apter, A; Connors, M; Litt, M; McCusker, C; Onyirimba, F; Reisine, S; ZuWallack, R, 2003)
"Presenting a case of acute theophylline and salbutamol overdose with distributive shock."3.96Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose. ( Chandrasekaran, VP; Muruga, B; Parthasarathy, A, 2020)
" Laboratory findings showed hypokalemia, hypophosphatemia, and lactic acidosis."3.78Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. ( Hantson, P; Manara, A; Thys, F; Vanpee, D, 2012)
"Albuterol overdose can lead to tachycardia, hypotension, tremor, hypokalemia, and hyperglycemia in children."3.72Hypoglycemia after albuterol overdose in a pediatric patient. ( Duman, M; Ozdemir, D; Tuncok, Y; Unal, N; Yilmaz, E, 2004)
"The cases of two asthmatic adolescents who overdosed on albuterol are presented."3.68Propranolol treatment of albuterol poisoning in two asthmatic patients. ( Henretig, F; Joffe, M; Ramoska, EA; Spiller, HA, 1993)
" Although transient, the dose-response relationship and duration of effect is unknown."1.29Hypokalemia after pediatric albuterol overdose: a case series. ( Leikin, JB; Linowiecki, KA; Paloucek, F; Soglin, DF, 1994)
"Hypoglycemia has previously been reported in newborns of mothers following prolonged use of sympathomimetics used as tocolytic therapy."1.28Hypoglycemia following albuterol overdose in a child. ( Amitai, Y; Wasserman, D, 1992)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (36.84)18.2507
2000's4 (21.05)29.6817
2010's6 (31.58)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Chandrasekaran, VP2
Parthasarathy, A2
Muruga, B2
Aliaga, CA1
Arizon, LF1
Bermúdez, RM1
Castán, JAB1
Santandreu, AV1
Patel, M1
Pilcher, J1
Reddel, HK1
Pritchard, A1
Corin, A1
Helm, C1
Tofield, C1
Shaw, D1
Black, P1
Weatherall, M1
Beasley, R1
Senthilkumaran, S1
Shah, S1
Menezes, RG1
Thirumalaikolundusubramanian, P1
Schmitt, C1
Kervégant, M1
Ajaltouni, Z1
Tauber, M1
Tichadou, L1
de Haro, L1
Pillmann, F1
Boucher, A1
Payen, C1
Garayt, C1
Ibanez, H1
Dieny, A1
Doche, C1
Chuniaud, C1
Descotes, J1
Manara, A1
Hantson, P1
Vanpee, D1
Thys, F1
Habib, GS1
Saliba, WR1
Cohen, L1
Onyirimba, F1
Apter, A1
Reisine, S1
Litt, M1
McCusker, C1
Connors, M1
ZuWallack, R1
Ozdemir, D1
Yilmaz, E1
Duman, M1
Unal, N1
Tuncok, Y1
Wiley, JF1
Spiller, HA3
Krenzelok, EP1
Borys, DJ1
Leikin, JB1
Linowiecki, KA1
Soglin, DF1
Paloucek, F1
Ramoska, EA2
Henretig, FM1
Joffe, M2
Henretig, F1
Toet, AE1
te Biesebeek, JD1
Vleeming, W1
Wemer, J1
Meulenbelt, J1
de Wildt, DJ1
Wasserman, D1
Amitai, Y1
King, WD1
Holloway, M1
Palmisano, PA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Adherence Feedback for Improving Respiratory Medication Use[NCT00459368]2,698 participants (Actual)Interventional2007-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Patient Adherence to Inhaled Corticosteroids (ICS)

Adherence to ICS medication was measured during the last 3 months of the intervention (i.e., for the time period of 9-12 months post-randomization). Adherence was measured using pharmacy claims data, and represents the percent of prescribed medication taken. The normal range for this value is 0-100%. (NCT00459368)
Timeframe: 1 year

InterventionPercent of ICS medication taken (Mean)
Patient Medication Adherence Feedback21.3
Usual Care23.3

Reviews

1 review available for albuterol and Drug Overdose

ArticleYear
Albuterol overdose: a case report and differential diagnosis.
    Pediatric emergency care, 1992, Volume: 8, Issue:5

    Topics: Albuterol; Diagnosis, Differential; Drug Overdose; Female; Humans; Infant; Poisoning

1992

Trials

2 trials available for albuterol and Drug Overdose

ArticleYear
Metrics of salbutamol use as predictors of future adverse outcomes in asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2013, Volume: 43, Issue:10

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Asthma; Drug Overdose; Female; Humans; Male;

2013
Direct clinician-to-patient feedback discussion of inhaled steroid use: its effect on adherence.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:4

    Topics: Administration, Inhalation; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Drug Overdose; Drug The

2003

Other Studies

16 other studies available for albuterol and Drug Overdose

ArticleYear
Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Acidosis; Albuterol; Bronchodilator Agents; Calcium Gluconate; Charcoal; Drug Combinations; Drug Ove

2020
Lipid emulsion in theophylline and salbutamol overdose: Lipid sink theory (MS 25092).
    The American journal of emergency medicine, 2021, Volume: 45

    Topics: Albuterol; Drug Overdose; Emulsions; Humans; Lipids; Theophylline

2021
Severe hypokalemia secondary to abuse of β-adrenergic agonists in a pediatric patient: Case report.
    Jornal brasileiro de nefrologia, 2019, May-30, Volume: 42, Issue:2

    Topics: Adolescent; Adrenergic beta-Agonists; Albuterol; Drug Overdose; Factitious Disorders; Humans; Hypoka

2019
Salmeterol and lactic acidosis: clinical and educational aspects.
    CJEM, 2014, Volume: 16, Issue:1

    Topics: Acidosis, Lactic; Albuterol; Androstadienes; Asthma; Drug Overdose; Female; Humans; Intention; Lacti

2014
[Clonidine poisoning in a child: a case report].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2014, Volume: 21, Issue:11

    Topics: Adrenergic alpha-2 Receptor Agonists; Albuterol; Antihypertensive Agents; Betaxolol; Blood Pressure;

2014
Complex dream-enacting behavior in sleepwalking.
    Psychosomatic medicine, 2009, Volume: 71, Issue:2

    Topics: Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Consciousness Disorders; Diagnosis, Differential; D

2009
Salbutamol misuse or abuse with fatal outcome: a case-report.
    Human & experimental toxicology, 2011, Volume: 30, Issue:11

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Arrhythmogenic Right Ventricular Dysplasia; A

2011
Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone.
    CJEM, 2012, Volume: 14, Issue:6

    Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Albut

2012
Diabetic ketoacidosis associated with oral salbutamol overdose.
    The American journal of medicine, 2002, Dec-01, Volume: 113, Issue:8

    Topics: Administration, Oral; Adult; Albuterol; Asthma; Diabetic Ketoacidosis; Drug Overdose; Female; Follow

2002
Hypoglycemia after albuterol overdose in a pediatric patient.
    Pediatric emergency care, 2004, Volume: 20, Issue:7

    Topics: Adrenergic beta-Agonists; Albuterol; Charcoal; Child, Preschool; Diseases in Twins; Drug Overdose; F

2004
Unintentional albuterol ingestion in children.
    Pediatric emergency care, 1994, Volume: 10, Issue:4

    Topics: Albuterol; Blood Pressure; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Overdose;

1994
Hypokalemia after pediatric albuterol overdose: a case series.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:1

    Topics: Acute Disease; Albuterol; Child; Child, Preschool; Drug Overdose; Female; Humans; Hypokalemia; Infan

1994
A two-year retrospective study of accidental pediatric albuterol ingestions.
    Pediatric emergency care, 1993, Volume: 9, Issue:6

    Topics: Accidents, Home; Albuterol; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Overdose

1993
Propranolol treatment of albuterol poisoning in two asthmatic patients.
    Annals of emergency medicine, 1993, Volume: 22, Issue:9

    Topics: Adolescent; Albuterol; Asthma; Charcoal; Drug Overdose; Female; Gastric Lavage; Humans; Hypokalemia;

1993
Reduced survival after isoprenaline/dopamine in d,l-propranolol intoxicated rats.
    Human & experimental toxicology, 1996, Volume: 15, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Blood Gas Analysis; Blood

1996
Hypoglycemia following albuterol overdose in a child.
    The American journal of emergency medicine, 1992, Volume: 10, Issue:6

    Topics: Albuterol; Blood Glucose; Child, Preschool; Drug Overdose; Female; Humans; Hypoglycemia

1992