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albuterol and Bronchopulmonary Dysplasia

albuterol has been researched along with Bronchopulmonary Dysplasia in 22 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.

Research Excerpts

ExcerptRelevanceReference
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."9.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"To determine the incidence of cardiotoxicity in infants and children who receive continuous nebulized albuterol (CNA) for bronchospasm."7.68Safety of continuous nebulized albuterol for bronchospasm in infants and children. ( Crowley, MR; Grad, R; Katz, RW; Kelly, HW; McWilliams, BC; Murphy, SJ, 1993)
"Aerosolized albuterol is widely used, but its tolerability and efficacy in infants with severe bronchopulmonary dysplasia (sBPD) is not well established."5.41Tolerability and efficacy of two doses of aerosolized albuterol in ventilated infants with BPD: A randomized controlled crossover trial. ( Dysart, K; Jensen, E; Napolitano, N; Panitch, H; Soorikian, L; Zhang, H, 2021)
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."5.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"To determine the incidence of cardiotoxicity in infants and children who receive continuous nebulized albuterol (CNA) for bronchospasm."3.68Safety of continuous nebulized albuterol for bronchospasm in infants and children. ( Crowley, MR; Grad, R; Katz, RW; Kelly, HW; McWilliams, BC; Murphy, SJ, 1993)
"Albuterol is a specific beta-2 agonist that has been reported to be effective in treating infants and children with bronchospastic pulmonary disease."2.67A randomized placebo-controlled study to evaluate the effects of oral albuterol on pulmonary mechanics in ventilator-dependent infants at risk of developing BPD. ( Bhutani, VK; Fox, WW; Stefano, JL, 1991)
"IL-1Ra treatment prevented hyperoxia-induced alveolar disruption and airway fibrosis but, surprisingly, not the increase in methacholine-induced airway contraction."1.43Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist. ( Bourke, JE; Bui, C; Donovan, C; Lam, M; Lamanna, E; Nold, MF; Nold-Petry, CA; Royce, SG; Rudloff, I, 2016)
"We used a placebo-controlled standardized protocol to define the dose-response relationship to the beta-adrenergic bronchodilator salbutamol (albuterol) in 10 ventilator-dependent premature infants at a postnatal age of 13."1.28Dose-related bronchodilator response to aerosolized salbutamol (albuterol) in ventilator-dependent premature infants. ( Dehan, M; Denjean, A; Gaultier, C; Guimaraes, H; Migdal, M; Miramand, JL, 1992)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.64)18.7374
1990's10 (45.45)18.2507
2000's5 (22.73)29.6817
2010's3 (13.64)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Napolitano, N1
Dysart, K1
Soorikian, L1
Zhang, H1
Panitch, H1
Jensen, E1
Slaughter, JL1
Stenger, MR1
Reagan, PB1
Jadcherla, SR1
Royce, SG1
Nold, MF1
Bui, C1
Donovan, C1
Lam, M1
Lamanna, E1
Rudloff, I1
Bourke, JE1
Nold-Petry, CA1
Durlak, W1
Klimek, M1
Kwinta, P1
Wu, B1
Nielson, DW1
Hayes, D1
Kriss, VM1
Iocono, JA1
Dixon, BJ1
Collins, PB1
Ballard, HO1
Robin, B1
Kim, YJ1
Huth, J1
Klocksieben, J1
Torres, M1
Tepper, RS1
Castile, RG1
Solway, J1
Hershenson, MB1
Goldstein-Filbrun, A1
Halvorsen, T1
Skadberg, BT1
Eide, GE1
Røksund, OD1
Carlsen, KH1
Bakke, P1
Pfenninger, J1
Aebi, C1
Katz, RW1
Kelly, HW1
Crowley, MR1
Grad, R1
McWilliams, BC1
Murphy, SJ1
Fok, TF2
Monkman, S1
Dolovich, M1
Gray, S1
Coates, G1
Paes, B1
Rashid, F1
Newhouse, M1
Kirpalani, H2
De Boeck, K1
Smith, J1
Van Lierde, S1
Devlieger, H1
Lam, K1
Ng, PC1
So, HK1
Cheung, KL1
Wong, W1
So, KW1
Denjean, A2
Paris-Llado, J1
Zupan, V1
Debillon, T1
Kieffer, F1
Magny, JF1
Desfrères, L1
Llanas, B1
Guimaraes, H2
Moriette, G1
Voyer, M1
Dehan, M2
Breart, G1
Pianosi, PT1
Fisk, M1
Migdal, M1
Miramand, JL1
Gaultier, C1
Stefano, JL1
Bhutani, VK1
Fox, WW1
Koren, G1
Schmidt, B1
Tan, Y1
Santos, R1
Soldin, S1
Kraemer, R1
Schöni, MH1
Rotschild, A1
Solimano, A1
Puterman, M1
Smyth, J1
Sharma, A1
Albersheim, S1
Wilkie, RA1
Bryan, MH1
Kasian, GF1
Ninan, A1
Duncan, WJ1
Bingham, WT1
Mersal, A1
Tyrrell, MJ1
Sankaran, K1

Trials

11 trials available for albuterol and Bronchopulmonary Dysplasia

ArticleYear
Tolerability and efficacy of two doses of aerosolized albuterol in ventilated infants with BPD: A randomized controlled crossover trial.
    Pediatric pulmonology, 2021, Volume: 56, Issue:1

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Cross-Over

2021
Pulmonary function in bronchopulmonary dysplasia.
    Pediatric pulmonology, 2004, Volume: 37, Issue:3

    Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Child, Preschool;

2004
Respiratory response to salbutamol (albuterol) in ventilator-dependent infants with chronic lung disease: pressurized aerosol delivery versus intravenous injection.
    Intensive care medicine, 1993, Volume: 19, Issue:5

    Topics: Administration, Inhalation; Aerosols; Albuterol; Blood Gas Analysis; Blood Gas Monitoring, Transcuta

1993
Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebulizer in infants with bronchopulmonary dysplasia.
    Pediatric pulmonology, 1996, Volume: 21, Issue:5

    Topics: Aerosols; Albuterol; Bronchopulmonary Dysplasia; Cross-Over Studies; Dose-Response Relationship, Dru

1996
Response to bronchodilators in clinically stable 1-year-old patients with bronchopulmonary dysplasia.
    European journal of pediatrics, 1998, Volume: 157, Issue:1

    Topics: Administration, Inhalation; Airway Resistance; Albuterol; Bronchodilator Agents; Bronchopulmonary Dy

1998
Randomised crossover trial of salbutamol aerosol delivered by metered dose inhaler, jet nebuliser, and ultrasonic nebuliser in chronic lung disease.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:2

    Topics: Administration, Intranasal; Adrenergic beta-Agonists; Albuterol; Analysis of Variance; Blood Gas Mon

1998
Inhaled salbutamol and beclomethasone for preventing broncho-pulmonary dysplasia: a randomised double-blind study.
    European journal of pediatrics, 1998, Volume: 157, Issue:11

    Topics: Administration, Inhalation; Albuterol; Beclomethasone; Bronchodilator Agents; Bronchopulmonary Dyspl

1998
A randomized placebo-controlled study to evaluate the effects of oral albuterol on pulmonary mechanics in ventilator-dependent infants at risk of developing BPD.
    Pediatric pulmonology, 1991, Volume: 10, Issue:3

    Topics: Albuterol; Bronchopulmonary Dysplasia; Caffeine; Double-Blind Method; Heart Rate; Humans; Infant, Ne

1991
Respiratory response and pharmacokinetics of intravenous salbutamol in infants with bronchopulmonary dysplasia.
    Critical care medicine, 1990, Volume: 18, Issue:12

    Topics: Airway Resistance; Albuterol; Biomechanical Phenomena; Bronchopulmonary Dysplasia; Hemodynamics; Hum

1990
Increased compliance in response to salbutamol in premature infants with developing bronchopulmonary dysplasia.
    The Journal of pediatrics, 1989, Volume: 115, Issue:6

    Topics: Albuterol; Blood Pressure; Bronchopulmonary Dysplasia; Clinical Trials as Topic; Double-Blind Method

1989
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
    The Canadian journal of cardiology, 1988, Volume: 4, Issue:4

    Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertensio

1988

Other Studies

11 other studies available for albuterol and Bronchopulmonary Dysplasia

ArticleYear
Inhaled bronchodilator use for infants with bronchopulmonary dysplasia.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:1

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Cohort Stu

2015
Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist.
    American journal of respiratory cell and molecular biology, 2016, Volume: 55, Issue:6

    Topics: Airway Remodeling; Albuterol; Animals; Bronchial Hyperreactivity; Bronchopulmonary Dysplasia; Diseas

2016
Regional lung ventilation pattern in preschool children with bronchopulmonary dysplasia is modified by bronchodilator response.
    Pediatric pulmonology, 2017, Volume: 52, Issue:3

    Topics: Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Child, Preschool; Electric Impedance;

2017
Should inhaled beta-agonists or lung function testing be routine in prematurely born infants with chronic lung disease?
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2008, Volume: 9, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Bronchopulmonary Dysplasia; Chronic

2008
Varicose bronchiectasis and bronchopulmonary dysplasia.
    Respiratory care, 2009, Volume: 54, Issue:11

    Topics: Albuterol; Bronchiectasis; Bronchodilator Agents; Bronchopulmonary Dysplasia; Chest Wall Oscillation

2009
Pulmonary outcome in adolescents of extreme preterm birth: a regional cohort study.
    Acta paediatrica (Oslo, Norway : 1992), 2004, Volume: 93, Issue:10

    Topics: Adolescent; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchopulmon

2004
Safety of continuous nebulized albuterol for bronchospasm in infants and children.
    Pediatrics, 1993, Volume: 92, Issue:5

    Topics: Acute Disease; Albuterol; Asthma; Bronchial Spasm; Bronchiolitis; Bronchopulmonary Dysplasia; Child,

1993
High frequency ventilation trial. Nine year follow up of lung function.
    Early human development, 2000, Volume: 57, Issue:3

    Topics: Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Child; Female; Follow-Up Studies; High

2000
Dose-related bronchodilator response to aerosolized salbutamol (albuterol) in ventilator-dependent premature infants.
    The Journal of pediatrics, 1992, Volume: 120, Issue:6

    Topics: Aerosols; Albuterol; Bronchoconstriction; Bronchopulmonary Dysplasia; Dose-Response Relationship, Dr

1992
Improvement from pulmonary hyperinflation and bronchial obstruction following sympathomimetics systemically given in infants with broncho-pulmonary diseases.
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1990, Volume: 174, Issue:2

    Topics: Airway Resistance; Albuterol; Bronchitis; Bronchopulmonary Dysplasia; Cystic Fibrosis; Humans; Hyali

1990
Effect of bronchodilators on airway resistance in ventilator-dependent neonates with chronic lung disease.
    The Journal of pediatrics, 1987, Volume: 111, Issue:2

    Topics: Airway Resistance; Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Chronic Disease; Dr

1987