albuterol has been researched along with Bronchiolitis, Viral in 44 studies
Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Bronchiolitis, Viral: An acute inflammatory disease of the lower RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Computerized lung sounds analysis with quantification of wheezing and crackles and a clinical score were used during a double blind, randomized, controlled nebulized treatment pilot study." | 2.73 | Computerized acoustic assessment of treatment efficacy of nebulized epinephrine and albuterol in RSV bronchiolitis. ( Beck, R; Bentur, L; Elias, N; Godfrey, S; Shoval, S; Talmon, G; Tov, N, 2007) |
| " This emphasizes the need for well-designed research to develop optimal dosage regimens in paediatric patients with bronchiolitis." | 1.29 | Pattern of drug usage in bronchiolitis. ( Nahata, MC; Schad, PA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.64) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 15 (34.09) | 29.6817 |
| 2010's | 12 (27.27) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Wall, MA | 1 |
| Brown, MA | 1 |
| Paluch, L | 1 |
| Rodriguez-Martinez, CE | 2 |
| Nino, G | 2 |
| Castro-Rodriguez, JA | 2 |
| Perez, GF | 1 |
| Sossa-Briceño, MP | 2 |
| Buendia, JA | 1 |
| Acuña-Cordero, R | 1 |
| Midulla, F | 1 |
| Kanjanapradap, T | 1 |
| Deerojanawong, J | 1 |
| Sritippayawan, S | 1 |
| Prapphal, N | 1 |
| Bradshaw, ML | 1 |
| Déragon, A | 1 |
| Puligandla, P | 1 |
| Emeriaud, G | 1 |
| Canakis, AM | 1 |
| Fontela, PS | 1 |
| Grewal, S | 1 |
| Klassen, TP | 2 |
| Wu, S | 2 |
| Baker, C | 2 |
| Lang, ME | 1 |
| Schrager, SM | 2 |
| Liley, FF | 1 |
| Papa, C | 1 |
| Mira, V | 1 |
| Balkian, A | 1 |
| Mason, WH | 1 |
| Naz, F | 1 |
| Raza, AB | 1 |
| Ijaz, I | 1 |
| Kazi, MY | 1 |
| Heaton, VL | 1 |
| Tan, NB | 1 |
| Marco, L | 1 |
| Zhang, L | 1 |
| Badgett, RG | 1 |
| Vindhyal, M | 1 |
| Stirnaman, JT | 1 |
| Gibson, CM | 1 |
| Halaby, R | 1 |
| Levin, DL | 1 |
| Garg, A | 1 |
| Hall, LJ | 1 |
| Slogic, S | 1 |
| Jarvis, JD | 1 |
| Leiter, JC | 1 |
| Postiaux, G | 1 |
| Louis, J | 1 |
| Labasse, HC | 1 |
| Gerroldt, J | 1 |
| Kotik, AC | 1 |
| Lemuhot, A | 1 |
| Patte, C | 1 |
| Chavasse, RJ | 1 |
| Bastian-Lee, Y | 1 |
| Seddon, P | 1 |
| Patel, H | 3 |
| Platt, RW | 2 |
| Pekeles, GS | 1 |
| Ducharme, FM | 1 |
| Gouin, S | 1 |
| Troe, JW | 2 |
| Versteegh, FG | 2 |
| Mooi-Kokenberg, EA | 2 |
| Van den Broeck, J | 2 |
| Hartling, L | 1 |
| Wiebe, N | 1 |
| Russell, K | 1 |
| Cox, RG | 1 |
| Saseen, JJ | 1 |
| Barbi, E | 1 |
| Neri, E | 1 |
| Ventura, A | 1 |
| Modl, M | 1 |
| Eber, E | 1 |
| Malle-Scheid, D | 1 |
| Weinhandl, E | 1 |
| Zach, MS | 1 |
| Beck, R | 1 |
| Elias, N | 1 |
| Shoval, S | 1 |
| Tov, N | 1 |
| Talmon, G | 1 |
| Godfrey, S | 2 |
| Bentur, L | 2 |
| Stokes, GM | 1 |
| Milner, AD | 2 |
| Hodges, IG | 1 |
| Henry, RL | 1 |
| Elphick, MC | 1 |
| Lo Iacono, F | 1 |
| Scalisi, D | 1 |
| Pitruzzella, E | 1 |
| Lo Iacono, G | 1 |
| Serwint, J | 1 |
| Chevallier, B | 1 |
| Aegerter, P | 1 |
| Parat, S | 1 |
| Bidat, E | 1 |
| Renaud, C | 1 |
| Lagardère, B | 1 |
| Nahata, MC | 1 |
| Schad, PA | 1 |
| Goodman, BT | 1 |
| Chambers, TL | 1 |
| Torres, A | 1 |
| Anders, M | 1 |
| Anderson, P | 1 |
| Heulitt, MJ | 1 |
| Harrison, AM | 1 |
| Boeing, NM | 1 |
| Domachowske, JB | 1 |
| Piedmonte, MR | 1 |
| Kanter, RK | 1 |
| Ray, MS | 1 |
| Singh, V | 1 |
| Amirav, I | 1 |
| Balanov, I | 1 |
| Gorenberg, M | 1 |
| Luder, AS | 1 |
| Newhouse, MT | 1 |
| Groshar, D | 1 |
| Rutter, N | 1 |
| Hiller, EJ | 1 |
| Ho, L | 1 |
| Collis, G | 1 |
| Landau, LI | 2 |
| Le Souef, PN | 1 |
| Sly, PD | 1 |
| Lanteri, CJ | 1 |
| Raven, JM | 1 |
| Schuh, S | 1 |
| Canny, G | 1 |
| Reisman, JJ | 1 |
| Kerem, E | 1 |
| Petric, M | 1 |
| Levison, H | 1 |
| Hughes, DM | 1 |
| Lesouëf, PN | 1 |
| Beardsmore, CS | 1 |
| Maayan, C | 1 |
| Bar-Yishay, E | 1 |
| Phelan, PD | 1 |
| Stocks, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nebulized Hypertonic Saline for Treatment of Viral Bronchiolitis[NCT00619918] | Phase 2/Phase 3 | 447 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| A Randomized Trial of Nebulized 3% Hypertonic Saline With Salbutamol in the Treatment of Acute Bronchiolitis in Pediatric Hospital[NCT02233985] | Phase 4 | 64 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| "FIBARRIX Clinical Evaluation of the Response to Chest Physiotherapy in Infants With Acute Bronchiolitis"[NCT02458300] | 77 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| Multicenter Randomized Controlled Trial: Evaluation of the Effects of Respiratory Physiotherapy, Placebo-controlled, in Infants With Moderate Acute Bronchiolitis[NCT03753802] | 168 participants (Anticipated) | Interventional | 2019-12-01 | Recruiting | |||
| "Are Steroids Efficacious in Hospitalized Patients With Bronchiolitis Who Show an Objective Clinical Improvement After Albuterol (Albuterol Responders)?"[NCT00798616] | 0 participants (Actual) | Interventional | Withdrawn (stopped due to We were unable to enroll a sufficient number of patients due to manpower.) | ||||
| Acoustic Assessment of Nebulized Epinephrine Versus Albuterol for RSV Bronchiolitis- a Double Blind Study[NCT00361452] | Phase 4 | 30 participants | Interventional | 2000-12-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Length of stay defined as date of discharge minute date of admission. (NCT00619918)
Timeframe: 1 month
| Intervention | Days (Mean) |
|---|---|
| Hypertonic Saline | 2.87 |
| Normal Saline | 2.86 |
Patients enrolled in the ED who required inpatient admission. Patients who required admission but were transferred to another facility due to lack of available beds were considered admitted for this outcome. Note, neither study site has an observation unit. (NCT00619918)
Timeframe: 1 day
| Intervention | participants (Number) | |
|---|---|---|
| Admitted | Discharged | |
| Hypertonic Saline | 55 | 141 |
| Normal Saline | 76 | 107 |
Each patient record the time of entry and measured the total hospital stay time in hours, recording the time of discharge to determine the total stay in hours. The hospital stay will be evaluated in hours. Staying hospitalized until they had mild respiratory stage scale scores for at least 2 hrs. (NCT02233985)
Timeframe: Throughout the stay for each patient until discharge. Follow-up will be continued for a period of 30 days in which they may present readmissions, complications or adverse effects.
| Intervention | hours (Median) |
|---|---|
| Hypertonic Saline Solution 3% (SHS 3%) | 8 |
| Saline Solution 0.9% (SS 0.9%) Group | 39.3 |
It is a validated clinical scale, sufficiently reliable measure of Severity of the respiratory distress. It consists of the summation score of the sibilance / crackling parameters (the largest of them), respiratory effort, pulmonary air inlet, oxygen saturation, heart rate and breathing rate. It is stratified into 3 levels of severity: mild from 0 to 5 points, moderate from 6 to 10 and severe from 10 to 16. (NCT02233985)
Timeframe: Basal, 30 minutes after the end of the first 3 continuous nebulization sessions, at 4 hours, 8 hours and every 24 hours during the entire hospital stay
| Intervention | units on a scale (Median) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Basal | 30 minutes | 4 hours | 8 hours | 12 hours | 24 hours | 48 hours | 72 hours | 96 hours | 120 hours | 144 hours | 196 hours | |
| Hypertonic Saline Solution 3% (HSS 3%) Group | 8 | 6 | 5 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Saline Solution 0.9% (SS 0.9%) Group | 8 | 8 | 8 | 8 | 7 | 7 | 7 | 6 | 5 | 3 | 6 | 4 |
7 reviews available for albuterol and Bronchiolitis, Viral
| Article | Year |
|---|---|
Bronchodilators and steroids should not be given in viral bronchiolitis - CON.
Topics: Adrenal Cortex Hormones; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Child; Child, Presc | 2019 |
Bronchodilators and steroids should not be given in viral bronchiolitis - PRO.
Topics: Adrenal Cortex Hormones; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Child; Child, Presc | 2019 |
Identifying and managing bronchiolitis.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Albuterol; Bronchiolitis, Viral; F | 2020 |
For which infants with viral bronchiolitis could it be deemed appropriate to use albuterol, at least on a therapeutic trial basis?
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Humans; Infant; Nasopharynx; Phenotype; Resp | 2021 |
A meta-analysis of randomized controlled trials evaluating the efficacy of epinephrine for the treatment of acute viral bronchiolitis.
Topics: Acute Disease; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Child Welfare; Child, Prescho | 2003 |
[20 cases of bronchiolitis in infants].
Topics: Albuterol; Ampicillin; Anti-Bacterial Agents; Betamethasone; Bronchiolitis, Viral; Cephalexin; Femal | 1980 |
Effect of RSV bronchiolitis practice guidelines on resource utilization.
Topics: Adrenergic beta-Antagonists; Albuterol; Bronchiolitis, Viral; Enzyme-Linked Immunosorbent Assay; Fem | 2001 |
19 trials available for albuterol and Bronchiolitis, Viral
| Article | Year |
|---|---|
Does nebulized hypertonic saline shorten hospitalization in young children with acute viral wheezing?
Topics: Administration, Inhalation; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Child, Preschool | 2018 |
Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Double-Blind Method; Emergency Medical Servi | 2014 |
Effectiveness of nebulized N-acetylcysteine solution in children with acute bronchiolitis.
Topics: Acetylcysteine; Acute Disease; Administration, Inhalation; Albuterol; Antiviral Agents; Bronchioliti | 2014 |
A prospective randomized controlled blinded study of three bronchodilators in infants with respiratory syncytial virus bronchiolitis on mechanical ventilation.
Topics: Airway Resistance; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Epinephrine; Female; Huma | 2008 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
Evaluation of an alternative chest physiotherapy method in infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Heart Rate; Humans; Infant; Male; Ne | 2011 |
A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis.
Topics: Acute Disease; Adrenergic beta-Agonists; Aerosols; Albuterol; Bronchiolitis, Viral; Double-Blind Met | 2002 |
Randomized, double-blind, placebo-controlled trial of oral albuterol in infants with mild-to-moderate acute viral bronchiolitis.
Topics: Acute Disease; Administration, Oral; Albuterol; Anti-Inflammatory Agents; Bronchiolitis, Viral; Doub | 2003 |
No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Anti-Asthmatic Agents; Bronchiolitis, Viral; Bronchodilator Agents; Cromolyn Sodium; Drug | 2003 |
No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis.
Topics: Albuterol; Anti-Asthmatic Agents; Bronchiolitis, Viral; Bronchodilator Agents; Cromolyn Sodium; Drug | 2003 |
A meta-analysis of randomized controlled trials evaluating the efficacy of epinephrine for the treatment of acute viral bronchiolitis.
Topics: Acute Disease; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Child Welfare; Child, Prescho | 2003 |
Does bronchodilator responsiveness in infants with bronchiolitis depend on age?
Topics: Age Factors; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Forced Expiratory Volum | 2005 |
Computerized acoustic assessment of treatment efficacy of nebulized epinephrine and albuterol in RSV bronchiolitis.
Topics: Administration, Inhalation; Albuterol; Auscultation; Bronchiolitis, Viral; Diagnosis, Computer-Assis | 2007 |
Nebulised therapy in acute severe bronchiolitis in infancy.
Topics: Acute Disease; Aerosols; Albuterol; Atropine Derivatives; Bronchiolitis, Viral; Clinical Trials as T | 1983 |
[Comparative study of nebulized sambutol against placebo in the acute phase of bronchiolitis in 33 infants aged 1 to 6 months].
Topics: Acute Disease; Albuterol; Bronchiolitis, Viral; Double-Blind Method; Drug Evaluation; Drug Tolerance | 1995 |
Efficacy of metered-dose inhaler administration of albuterol in intubated infants.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Albuterol; Bronchiolitis, Viral; Bro | 1997 |
Comparison of nebulized adrenaline versus salbutamol in wheeze associated respiratory tract infection in infants.
Topics: Administration, Inhalation; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Child, Preschool | 2002 |
Effect of salbutamol on oxygen saturation in bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Double-Blind Method; Female; Humans; Infant; Infant, Newborn; Male; | 1991 |
Do wheezy infants recovering from bronchiolitis respond to inhaled salbutamol?
Topics: Acute Disease; Albuterol; Bronchiolitis, Viral; Double-Blind Method; Functional Residual Capacity; H | 1991 |
Nebulized albuterol in acute bronchiolitis.
Topics: Acute Disease; Albuterol; Bronchiolitis, Viral; Double-Blind Method; Female; Heart Rate; Humans; Inf | 1990 |
19 other studies available for albuterol and Bronchiolitis, Viral
| Article | Year |
|---|---|
Cost-effectiveness analysis of phenotypic-guided versus guidelines-guided bronchodilator therapy in viral bronchiolitis.
Topics: Administration, Inhalation; Albuterol; Bronchiolitis; Bronchiolitis, Viral; Bronchodilator Agents; C | 2021 |
Treatment of severe bronchiolitis: A survey of Canadian pediatric intensivists.
Topics: Adult; Albuterol; Anti-Bacterial Agents; Bronchiolitis, Viral; Canada; Cannula; Child; Continuous Po | 2018 |
The tale of 2 trials: disentangling contradictory evidence on hypertonic saline for acute bronchiolitis.
Topics: Albuterol; Bronchiolitis; Bronchiolitis, Viral; Bronchodilator Agents; Female; Humans; Length of Sta | 2014 |
Nebulized hypertonic saline for bronchiolitis.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Humans; Length of Stay; Male; Saline | 2014 |
In reply.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Humans; Length of Stay; Male; Saline | 2014 |
Multiple-dose hypertonic saline decreases bronchiolitis admissions.
Topics: Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Female; Humans; Length of Stay; Male; Saline | 2015 |
A Living Systematic Review of Nebulized Hypertonic Saline for Acute Bronchiolitis in Infants.
Topics: Albuterol; Bronchiolitis; Bronchiolitis, Viral; Bronchodilator Agents; Female; Humans; Length of Sta | 2015 |
How do we treat wheezing infants? Evidence or anecdote.
Topics: Adrenal Cortex Hormones; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Humans; Infant; Ipr | 2002 |
Repair of incarcerated inguinal hernia in an infant with acute viral bronchiolitis.
Topics: Acute Disease; Albuterol; Anesthesia, Epidural; Anesthesia, Inhalation; Bronchiolitis, Viral; Bronch | 2004 |
Epinephrine is efficacious for outpatient treatment of bronchiolitis.
Topics: Acute Disease; Albuterol; Ambulatory Care; Bronchiolitis, Viral; Bronchodilator Agents; Epinephrine; | 2004 |
Nomina sunt consequentia rerum: time for a change in the definition of bronchiolitis?
Topics: Age Factors; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Epinephrine; Humans; Infant; In | 2004 |
Efficacy of albuterol in the management of bronchiolitis.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Albuterol; Bronchiolitis, Viral; Child; | 1995 |
Pattern of drug usage in bronchiolitis.
Topics: Albuterol; Aminophylline; Bronchiolitis, Viral; Drug Utilization; Female; Glucocorticoids; Humans; I | 1994 |
Bronchodilators for bronchiolitis?
Topics: Aerosols; Albuterol; Bronchiolitis, Viral; Bronchodilator Agents; Hospitalization; Humans; Infant; U | 1993 |
Beta-agonist aerosol distribution in respiratory syncytial virus bronchiolitis in infants.
Topics: Acute Disease; Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Albuterol; Bronchioli | 2002 |
Effect of bronchodilators on respiratory resistance in infants and young children with bronchiolitis and wheezy bronchitis.
Topics: Airway Resistance; Albuterol; Bronchiolitis, Viral; Bronchitis; Bronchodilator Agents; Child, Presch | 1975 |
Effect of salbutamol on respiratory mechanics in bronchiolitis.
Topics: Administration, Inhalation; Albuterol; Bronchiolitis, Viral; Female; Forced Expiratory Flow Rates; H | 1987 |
Can thoracic gas volume be measured in infants with airways obstruction?
Topics: Airway Obstruction; Airway Resistance; Albuterol; Bronchiolitis, Viral; Cystic Fibrosis; Functional | 1986 |
Management of severe viral bronchiolitis and severe acute asthma.
Topics: Acute Disease; Airway Obstruction; Albuterol; Aminophylline; Anti-Bacterial Agents; Asthma; Bronchio | 1974 |