albuterol has been researched along with Altitude Hypoxia in 11 studies
Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Altitude Hypoxia: Low ambient oxygen tension associated with ALTITUDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High altitude pulmonary edema (HAPE) is the leading cause of death from altitude illness and rapid descent is often considered a life-saving foundation of therapy." | 1.34 | Treatment of high altitude pulmonary edema at 4240 m in Nepal. ( Fagenholz, PJ; Gutman, JA; Harris, NS; Murray, AF, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Chen, H | 1 |
| Li, R | 1 |
| Fu, W | 1 |
| Yao, C | 1 |
| Chandramoorthi, GD | 1 |
| Piramanayagam, S | 1 |
| Marimuthu, P | 1 |
| Luks, AM | 1 |
| McIntosh, SE | 1 |
| Grissom, CK | 1 |
| Auerbach, PS | 1 |
| Rodway, GW | 1 |
| Schoene, RB | 1 |
| Zafren, K | 1 |
| Hackett, PH | 1 |
| Cruden, NL | 1 |
| Newby, DE | 1 |
| Webb, DJ | 1 |
| Bärtsch, P | 1 |
| Mairbäurl, H | 1 |
| Basnyat, B | 1 |
| Pandit, A | 1 |
| Fagenholz, PJ | 1 |
| Gutman, JA | 1 |
| Murray, AF | 1 |
| Harris, NS | 1 |
| Hashimoto, F | 1 |
| McWilliams, B | 1 |
| Qualls, C | 1 |
| Voelkel, NF | 1 |
| Sartori, C | 1 |
| Allemann, Y | 1 |
| Duplain, H | 1 |
| Lepori, M | 1 |
| Egli, M | 1 |
| Lipp, E | 1 |
| Hutter, D | 1 |
| Turini, P | 1 |
| Hugli, O | 1 |
| Cook, S | 1 |
| Nicod, P | 1 |
| Scherrer, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness: A Randomized Controlled Trial[NCT02972411] | 30 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| The Effect of Nebulized Albuterol on Donor Oxygenation[NCT00310401] | Phase 2 | 506 participants (Actual) | Interventional | 2007-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome was the change in oxygenation as measured by change in the PaO2/FiO2 ratio from study enrollment to organ procurement (NCT00310401)
Timeframe: Change from enrollment to organ procurement (about ~40h after enrollment)
| Intervention | cmH2O (Median) |
|---|---|
| Albuterol | 49 |
| Saline | 40 |
Number of lungs procured and used for transplantation (NCT00310401)
Timeframe: 72 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Albuterol | 74 |
| Saline | 78 |
Chest radiographs were scored using a radiographic score that scored each quadrant for extent of radiographic infiltrates on a scale of 0 to 4, then summed each quadrant for a total score from 0 (no infiltrates) to 16 (extensive infiltrates in all 4 radiographic quadrants). (NCT00310401)
Timeframe: change from enrollment to organ procurement (about ~40h after enrollment)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Enrollment | at organ procurement (about ~40h after enrollment) | |
| Albuterol | 4.7 | 5.0 |
| Saline | 4.6 | 4.4 |
Static compliance of the respiratory system using plateau pressure (Pplat) measured at end-inspiration and calculated using the equation static compliance = tidal volume/(Pplat - PEEP) (NCT00310401)
Timeframe: baseline and at organ procurement (about ~40h after enrollment)
| Intervention | ml/cmH2O (Mean) | |
|---|---|---|
| baseline | at organ procurement (mean ~40h after enrollment) | |
| Albuterol | 48 | 52 |
| Saline | 50 | 56 |
3 trials available for albuterol and Altitude Hypoxia
| Article | Year |
|---|---|
The effects of respiratory inhaled drugs on the prevention of acute mountain sickness.
Topics: Acute Disease; Adolescent; Adult; Albuterol; Albuterol, Ipratropium Drug Combination; Altitude Sickn | 2018 |
Pulmonary ventilatory function decreases in proportion to increasing altitude.
Topics: Adult; Aged; Albuterol; Altitude; Altitude Sickness; Bronchodilator Agents; Cohort Studies; Female; | 1997 |
Salmeterol for the prevention of high-altitude pulmonary edema.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Altitude Sickness; Biologica | 2002 |
8 other studies available for albuterol and Altitude Hypoxia
| Article | Year |
|---|---|
An insilico approach to high altitude pulmonary edema - Molecular modeling of human beta2 adrenergic receptor and its interaction with Salmeterol & Nifedipine.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Altitude Sickness; Amino Acid Sequence; Binding Site | 2008 |
Wilderness Medical Society consensus guidelines for the prevention and treatment of acute altitude illness.
Topics: Acetazolamide; Acute Disease; Albuterol; Altitude Sickness; Brain Edema; Carbolines; Dexamethasone; | 2010 |
Salmeterol for the prevention of high-altitude pulmonary edema.
Topics: Albuterol; Altitude Sickness; Biological Transport, Active; Epithelium; Hemodynamics; Humans; Nitric | 2002 |
Salmeterol for the prevention of high-altitude pulmonary edema.
Topics: Adrenergic beta-Agonists; Albuterol; Altitude Sickness; Blood Pressure; Bronchodilator Agents; Echoc | 2002 |
Salmeterol for the prevention of high-altitude pulmonary edema.
Topics: Administration, Inhalation; Albuterol; Altitude Sickness; Humans; Pulmonary Edema | 2002 |
The physiologic basis of high-altitude diseases.
Topics: Adrenergic beta-Agonists; Albuterol; Altitude Sickness; Animals; Extravascular Lung Water; Humans; P | 2005 |
Treatment of high altitude pulmonary edema at 4240 m in Nepal.
Topics: Acetazolamide; Adult; Albuterol; Altitude; Altitude Sickness; Bed Rest; Emergency Treatment; Female; | 2007 |
High-altitude pulmonary edema.
Topics: Adrenergic beta-Agonists; Albuterol; Altitude Sickness; Biological Transport, Active; Epithelium; Hu | 2002 |