Page last updated: 2024-10-22

albuterol and Alkalosis, Respiratory

albuterol has been researched along with Alkalosis, Respiratory in 2 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Alkalosis, Respiratory: A state due to excess loss of carbon dioxide from the body. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We present a 19-month-old boy with a history of asthma who presented to the pediatric emergency department with noisy breathing and tachypnea partially responsive to albuterol."3.76A 19-month-old boy with recurrent respiratory distress. ( Cross, KP; Herr, SM; Randell, KA, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cancado, JE1
Mendes, ES1
Arana, J1
Horvath, G1
Monzon, ME1
Salathe, M1
Wanner, A1
Cross, KP1
Randell, KA1
Herr, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Evidence of pH Dependent ß2 Adrenergic Transport Mechanisms in the Airway[NCT01216748]10 participants (Actual)Interventional2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in Airway Blood Flow After 180μg Albuterol by Inhalation (ΔQaw) vs Baseline

Effect of airway pH on albuterol responsiveness as reflected by the change in airway blood flow after 180μg albuterol by inhalation (ΔQaw) vs baseline. (NCT01216748)
Timeframe: 15 minutes after albuterol inhalation

Interventionchanges from baseline in μl.min-1.ml-1 (Mean)
quiet breathingeucapnic hyperventilationhypocapnic hyperventilationhypercapnic hyperventilation
Health Controls16.814.5-0.22.0

Exhaled Breath Condensate (EBC) pH Variation

"EBC samples were collected at each respiratory maneuver by directing the subject's exhaled breath into a pre-cooled (-10C) tube for 10 min.~pH was measured immediately after collection." (NCT01216748)
Timeframe: 10 minutes after each respiratory manouver.

InterventionpH (Mean)
quiet breathinghypocapnic hyperventilationhypercapnic hyperventilationeucapnic hyperventilation
Health Controls6.396.316.595.88

Trials

1 trial available for albuterol and Alkalosis, Respiratory

ArticleYear
Effect of airway acidosis and alkalosis on airway vascular smooth muscle responsiveness to albuterol.
    BMC pharmacology & toxicology, 2015, Apr-02, Volume: 16

    Topics: Acidosis, Respiratory; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Albut

2015

Other Studies

1 other study available for albuterol and Alkalosis, Respiratory

ArticleYear
A 19-month-old boy with recurrent respiratory distress.
    Pediatric emergency care, 2010, Volume: 26, Issue:2

    Topics: Acid-Base Equilibrium; Albuterol; Alkalosis, Respiratory; Aspirin; Asthma; Bicarbonates; Bites, Huma

2010