albuterol and Airway Obstruction studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

Excerpt	Relevance	Reference
"The pentosidine levels did not significantly differ between the two asthmatic subgroups with and without airway obstruction."	9.16	Association of airway pentosidine levels with bronchodilator response mediated by salbutamol administration in asthmatic patients. ( Hirata, K; Kanazawa, H; Tamagaki, G, 2012)
"Aerosolised albuterol is an effective bronchodilator in horses with recurrent airway obstruction."	9.15	Comparative efficacy of inhaled albuterol between two hand-held delivery devices in horses with recurrent airway obstruction. ( Bertin, FR; Couëtil, LL; Ivester, KM, 2011)
"To determine the onset, magnitude, and duration of bronchodilation after administration of aerosolized salmeterol xinafoate in horses with recurrent airway obstruction."	9.09	Efficacy of salmeterol xinafoate in horses with recurrent airway obstruction. ( Henrikson, SL; Rush, BR, 2001)
"Twenty-one patients with chronic bronchitis and reversible airway obstruction participated in two single-blind, cross-over, placebo-controlled studies in inhaled clenbuterol - a new bronchodilator - and salbutamol."	9.05	A comparison between inhaled clenbuterol and salbutamol in chronic bronchitis with reversible airway obstruction. ( Baronti, A; Grieco, A; Vibelli, C, 1980)
"Indoramin, an alpha adrenoreceptor antagonist, was given in tablet form, in addition to regular salbutamol by aerosol, to 30 patients with airway obstruction."	9.04	Indoramin--an alpha adrenoreceptor antagonist for airway obstruction. ( Campbell, IA; Dyson, AJ, 1977)
"Evaluation of the efficacy of nebulized magnesium sulfate (MgSO4) alone and in combination with salbutamol in acute asthma."	7.83	The efficacy of nebulized magnesium sulfate alone and in combination with salbutamol in acute asthma. ( Ali, MA; El-Garhy, OH; Sarhan, HA; Youssef, NA, 2016)
"In patients with asthma, increased airway obstruction results in greater reductions in R(0) and Edyn after albuterol use."	7.75	Effects of airway obstruction on albuterol-mediated variations in the resistive and elastic properties of the respiratory system of patients with asthma. ( de Melo, PL; Jansen, JM; Lopes, AJ; Veiga, J, 2009)
"Fifty children primarily with moderate-to-severe asthma were followed with measurements of urinary LTE(4), monitoring of FEV(1), and albuterol use."	7.73	Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction. ( Gelfand, EW; Rabinovitch, N; Zhang, L, 2006)
"Inhaled acetaldehyde and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in asthmatics by a mechanism believed to involve histamine release from airway mast cells."	7.71	Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness. ( Cervera, A; Gutiérrez, V; Liñana, J; Prieto, L, 2002)
"To determine whether pulmonary distribution of aerosolized technetium Tc 99m pentetate is improved after inhalation of a single dose of albuterol sulfate in horses susceptible to recurrent airway obstruction (heaves)."	7.70	Pulmonary distribution of aerosolized technetium Tc 99m pentetate after administration of a single dose of aerosolized albuterol sulfate in horses with recurrent airway obstruction. ( Davis, EG; Hakala, JE; Hoskinson, JJ; Matson, CJ; Rush, BR, 1999)
"To determine the dose of aerosolized albuterol sulfate required to cause bronchodilation in horses with recurrent airway obstruction (RAO) and duration of this effect."	7.70	Aerosolized albuterol sulfate used as a bronchodilator in horses with recurrent airway obstruction. ( Berney, C; Derksen, FJ; Hakala, JE; Matson, CJ; Olszewski, MA; Robinson, NE; Ruth, DT, 1999)
"Multiple aspects of lung function were measured in 17 cystic fibrosis (CF) patients on four occasions: without therapy (0); with oral theophylline medication (Th); after inhalation of salbutamol (beta 2); and with combined medication (Th + beta 2)."	7.67	Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics. ( Eber, E; Oberwaldner, B; Zach, MS, 1988)
"Intravenous injections of aminophylline (250 mg) and tablets of theophylline (Neulin) (400 mg) were given, on separate occasions, to 10 patients with partially reversible severe airway obstruction."	7.65	Aminophylline injection and theophylline tablets: Acute response in partially reversible chronic airway obstruction. ( Freitag, A, 1976)
"Both procaterol and albuterol were highly effective in improving pulmonary function and controlling symptoms of asthma; both were well tolerated."	6.67	Evaluation of procaterol and albuterol (salbutamol) aerosol in the treatment of asthma. ( Mazza, JA; Reed, CE; Tashkin, DP, 1992)
"Post hoc descriptive analysis of data stratified by FAO category (screening post-albuterol FEV1/FVC	5.19	Fixed airflow obstruction in asthma: a descriptive study of patient profiles and effect on treatment responses. ( Chipps, BE; Tashkin, DP; Trudo, F; Zangrilli, JG, 2014)
"The pentosidine levels did not significantly differ between the two asthmatic subgroups with and without airway obstruction."	5.16	Association of airway pentosidine levels with bronchodilator response mediated by salbutamol administration in asthmatic patients. ( Hirata, K; Kanazawa, H; Tamagaki, G, 2012)
"Aerosolised albuterol is an effective bronchodilator in horses with recurrent airway obstruction."	5.15	Comparative efficacy of inhaled albuterol between two hand-held delivery devices in horses with recurrent airway obstruction. ( Bertin, FR; Couëtil, LL; Ivester, KM, 2011)
"This study assessed the effect of the leukotriene receptor antagonist montelukast on hypertonic saline-induced airway obstruction."	5.10	Montelukast attenuates the airway response to hypertonic saline in moderate-to-severe COPD. ( Böhme, S; Jörres, RA; Kanniess, F; Magnussen, H; Nielsen-Gode, D; Richter, K; Zühlke, IE, 2003)
"To determine the onset, magnitude, and duration of bronchodilation after administration of aerosolized salmeterol xinafoate in horses with recurrent airway obstruction."	5.09	Efficacy of salmeterol xinafoate in horses with recurrent airway obstruction. ( Henrikson, SL; Rush, BR, 2001)
"The efficacy and safety of orally administered procaterol hydrochloride, a potent beta 2-adrenergic bronchodilator, was compared with that of albuterol in an eight-center, double-blind study conducted in 223 patients with mild to moderate, reversible bronchial airway obstruction."	5.06	A comparison of oral procaterol and albuterol in reversible airflow obstruction. ( Beaupre, A; Boulet, LP; Brandon, ML; Busse, WW; Chervinsky, P; Mazza, J; Petty, TL; Schoenweter, W, 1988)
"Metaproterenol (15 mg) and albuterol (5 mg) solutions were each nebulized and delivered to 20 patients with reversible airway obstruction utilizing intermittent positive pressure ventilation in a double-blind comparison."	5.06	A comparison of albuterol and metaproterenol nebulizer solutions. ( Campbell, SC; Habib, MP; Pinnas, JL; Shon, BY, 1987)
"Twenty-one patients with chronic bronchitis and reversible airway obstruction participated in two single-blind, cross-over, placebo-controlled studies in inhaled clenbuterol - a new bronchodilator - and salbutamol."	5.05	A comparison between inhaled clenbuterol and salbutamol in chronic bronchitis with reversible airway obstruction. ( Baronti, A; Grieco, A; Vibelli, C, 1980)
"Indoramin, an alpha adrenoreceptor antagonist, was given in tablet form, in addition to regular salbutamol by aerosol, to 30 patients with airway obstruction."	5.04	Indoramin--an alpha adrenoreceptor antagonist for airway obstruction. ( Campbell, IA; Dyson, AJ, 1977)
"The indications for heliox during mechanical ventilation are lower-airway obstruction, especially with hypercarbia; need to enhance aerosol delivery to lung periphery; and need to facilitate weaning from mechanical ventilation."	4.83	Heliox during mechanical ventilation. ( Venkataraman, ST, 2006)
"Evaluation of the efficacy of nebulized magnesium sulfate (MgSO4) alone and in combination with salbutamol in acute asthma."	3.83	The efficacy of nebulized magnesium sulfate alone and in combination with salbutamol in acute asthma. ( Ali, MA; El-Garhy, OH; Sarhan, HA; Youssef, NA, 2016)
"In patients with asthma, increased airway obstruction results in greater reductions in R(0) and Edyn after albuterol use."	3.75	Effects of airway obstruction on albuterol-mediated variations in the resistive and elastic properties of the respiratory system of patients with asthma. ( de Melo, PL; Jansen, JM; Lopes, AJ; Veiga, J, 2009)
"Fifty children primarily with moderate-to-severe asthma were followed with measurements of urinary LTE(4), monitoring of FEV(1), and albuterol use."	3.73	Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction. ( Gelfand, EW; Rabinovitch, N; Zhang, L, 2006)
"Inhaled acetaldehyde and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in asthmatics by a mechanism believed to involve histamine release from airway mast cells."	3.71	Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness. ( Cervera, A; Gutiérrez, V; Liñana, J; Prieto, L, 2002)
"To determine whether pulmonary distribution of aerosolized technetium Tc 99m pentetate is improved after inhalation of a single dose of albuterol sulfate in horses susceptible to recurrent airway obstruction (heaves)."	3.70	Pulmonary distribution of aerosolized technetium Tc 99m pentetate after administration of a single dose of aerosolized albuterol sulfate in horses with recurrent airway obstruction. ( Davis, EG; Hakala, JE; Hoskinson, JJ; Matson, CJ; Rush, BR, 1999)
"To determine the dose of aerosolized albuterol sulfate required to cause bronchodilation in horses with recurrent airway obstruction (RAO) and duration of this effect."	3.70	Aerosolized albuterol sulfate used as a bronchodilator in horses with recurrent airway obstruction. ( Berney, C; Derksen, FJ; Hakala, JE; Matson, CJ; Olszewski, MA; Robinson, NE; Ruth, DT, 1999)
" Bronchial challenge tests were carried out with cumulative doses of inhaled carbachol in 10 healthy children (aged 7-14 yrs) and 50 asthmatic children (aged 5-15 yrs)."	3.69	Oscillatory pressure transients after flow interruption during bronchial challenge test in children. ( Frey, U; Kraemer, R, 1997)
"We compared mood variables, symptom severity, albuterol use, and peak expiratory flow rate (PEFR) measured three times daily over a 21-day period in 21 adults with moderate to severe asthma."	3.69	Perception of airway obstruction in asthma: sequential daily analyses of symptoms, peak expiratory flow rate, and mood. ( Affleck, G; Apter, AJ; Barrows, E; Reisine, ST; Tennen, HA; Wells, M; Willard, A; ZuWallack, RL, 1997)
"In guinea pigs passively sensitized to ovalbumin, sustained (6 days) subcutaneous infusion of (+/-)salbutamol (1 mg/kg/day) induced significant airway obstruction and heightened responsivity to airway spasmogens."	3.68	Exacerbation of airway hyperreactivity by (+/-)salbutamol in sensitized guinea pig. ( Hoshiko, K; Morley, J, 1993)
" We conclude that smooth muscle contraction is important in A23187-induced airway obstruction; 5-hydroxytryptamine, thromboxane A2 and lipoxygenase products may be involved in maintaining this response; and that this approach is useful for investigating reversal of ongoing airway constriction."	3.67	Reversal of A23187-induced airway constriction in the guinea pig. ( Silbaugh, SA; Stengel, PW, 1989)
" Inhalation of ovalbumin by sensitized guinea pigs induced three phases of airways obstruction: an early asthmatic response (EAR) peaking at 2 h, a late response (LAR) peaking at 17 h, and a further late response (LLAR) being observed at 72 h."	3.67	The effect of cromolyn sodium and albuterol on early and late phase bronchoconstriction and airway leukocyte infiltration after allergen challenge of nonanesthetized guinea pigs. ( Church, MK; Holgate, ST; Hutson, PA, 1988)
"Multiple aspects of lung function were measured in 17 cystic fibrosis (CF) patients on four occasions: without therapy (0); with oral theophylline medication (Th); after inhalation of salbutamol (beta 2); and with combined medication (Th + beta 2)."	3.67	Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics. ( Eber, E; Oberwaldner, B; Zach, MS, 1988)
"Intravenous injections of aminophylline (250 mg) and tablets of theophylline (Neulin) (400 mg) were given, on separate occasions, to 10 patients with partially reversible severe airway obstruction."	3.65	Aminophylline injection and theophylline tablets: Acute response in partially reversible chronic airway obstruction. ( Freitag, A, 1976)
"Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous disorders encompassing different phenotypes of airflow obstruction, which might differ in their response to treatment."	2.80	Treatment responsiveness of phenotypes of symptomatic airways obstruction in adults. ( Beasley, R; Bowles, D; Charles, T; Fingleton, J; Shirtcliffe, P; Strik, R; Travers, J; Weatherall, M; Williams, M, 2015)
"Data on the onset of action of COPD medications are lacking."	2.73	Fast onset of effect of budesonide/formoterol versus salmeterol/fluticasone and salbutamol in patients with chronic obstructive pulmonary disease and reversible airway obstruction. ( Lindberg, A; Pullerits, T; Radeczky, E; Szalai, Z, 2007)
" Dose-response curves were compared using an analysis of covariance."	2.69	Tolerance to beta-agonists during acute bronchoconstriction. ( Aldridge, RE; Cowan, JO; Flannery, EM; Hancox, RJ; Herbison, GP; McLachlan, CR; Taylor, DR; Town, GI, 1999)
" When parallel and linear cumulative dose-response curves were statistically compared on a logarithmic scale, the dose potency of salbutamol Turbuhaler vs salbutamol Diskhaler was 1."	2.69	Efficacy of cumulative doses of salbutamol administered via Turbuhaler or Diskhaler in patients with reversible airway obstruction. ( Arweström, E; Carlsson, LG; Friberg, K; Källén, A; Löfdahl, CG; Lunde, H, 1998)
" Salmeterol was well tolerated as assessed by pulse, blood pressure, haematological and biochemical variables and number of adverse events."	2.68	The efficacy and safety of inhaled salmeterol 50 microg bd in older patients with reversible airflow obstruction. ( Luce, P; Starke, ID, 1996)
"Finally, baseline airway obstruction correlated with the degree of bronchodilation achieved with MK-571 (r = -0."	2.67	Bronchodilation with a potent and selective leukotriene D4 (LTD4) receptor antagonist (MK-571) in patients with asthma. ( Bush, RK; Busse, WW; Gaddy, JN; Margolskee, DJ; Williams, VC, 1992)
" After each period, dose-response curves were measured on 4 study days with doubling doses of salbutamol, ipratropium, a combination of salbutamol and ipratropium, and placebo until a plateau in FEV1 was reached."	2.67	Separate and combined effects of corticosteroids and bronchodilators on airflow obstruction and airway hyperresponsiveness in asthma. ( Alting-Hebing, D; Breederveld, N; Koëter, GH; Postma, DS; van der Mark, TW; Wempe, JB, 1992)
"Both procaterol and albuterol were highly effective in improving pulmonary function and controlling symptoms of asthma; both were well tolerated."	2.67	Evaluation of procaterol and albuterol (salbutamol) aerosol in the treatment of asthma. ( Mazza, JA; Reed, CE; Tashkin, DP, 1992)
" To determine whether these drugs also protect against excessive airway narrowing, the effect of inhaled salbutamol on the position and shape of the dose-response curves for histamine or methacholine was investigated in 12 patients with asthma and 11 with chronic obstructive lung disease."	2.67	The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease. ( Bel, EH; Dijkman, JH; Sterk, PJ; Timmers, MC; Zwinderman, AH, 1991)
"A double-blind, randomized crossover trial was carried out in 10 patients with reversible airways obstruction to assess dose-response and duration of action of 0."	2.66	A comparison between fenoterol/ipratropium bromide combinations and salbutamol administered as nebulizer solutions assessing dose-response and duration of action. ( McIntosh, D, 1986)
" Increase of dosage did not lead to improved effectiveness."	2.65	[Parasympathicolytic drugs in treatment of obstructive lung diseases (author's transl)]. ( Gonsior, E; Meier-Sydow, J; Schultze-Werninghaus, G, 1979)
"Tremor was recorded with the higher doses of albuterol."	2.64	Albuterol and ephedrine in patients with reversible obstructive airway disease. ( Whitsett, TL, 1977)
"Rimiterol is an acceptable alternative to the short-acting isoprenaline but lacks the cardiovascular effects of isoprenaline and is an alternative to salbutamol where very prolonged action is unnecessary."	2.64	Comparison between the bronchodilator and cardiovascular effects of inhaling 0.5 mg. rimiterol ('Pulmadil') and 0.2 mg. salbutamol. ( Bianco, S; Kamburoff, PL; Prime, FJ, 1975)
"Status asthmaticus is a frequent cause of admission to a pediatric intensive care unit."	2.49	Pediatric status asthmaticus. ( Carroll, CL; Sala, KA, 2013)
"The sensitivity of detecting airway obstruction in these children by FEV1 was 15."	1.43	Assessment of Airway Bronchodilation by Spirometry Compared to Airway Obstruction in Young Children with Asthma. ( Bar-Yoseph, R; Bentur, L; Hakim, F; Livnat, G; Ofek, M; Vilozni, D, 2016)
"Airway obstruction was more severe in COPD patients as compared with controls (mean FEV1 and FEV1% predicted both P<0."	1.43	Characteristics of reversible and nonreversible COPD and asthma and COPD overlap syndrome patients: an analysis of salbutamol Easyhaler data. ( Gálffy, G; Kováts, Z; Müller, V; Odler, B; Orosz, M; Selroos, O; Tamási, L, 2016)
"We evaluated 21 patients with airway obstruction at the Department of Pulmonary Medicine, Samsun Medicalpark Hospital, Samsun, Turkey."	1.40	The relationship between early reversibility test and maximal inspiratory pressure in patients with airway obstruction. ( Bayrak, MG; Bostancı, O; Dirican, A; Ece, F; Karanfil, RC; Kaya, SO; Ozkaya, S, 2014)
"COPD was likely the predominant diagnosis but patients with asthma may have been included."	1.36	Lung hyperinflation and its reversibility in patients with airway obstruction of varying severity. ( Deesomchok, A; Forkert, L; Jensen, D; Lam, YM; O'Donnell, DE; Ofir, D; Webb, KA, 2010)
"Airway emergencies were the most common emergencies seen in the offices."	1.33	Preparedness of selected pediatric offices to respond to critical emergencies in children. ( Gausche-Hill, M; Santillanes, G; Sosa, B, 2006)
" Bronchial lability was characterized by (1) variability in mean daily peak expiratory flow rate and (2) bronchial responsiveness to either carbachol (as assessed by the threshold dose and the slope of the dose-response curve) or salbutamol (as assessed by the threshold dose and maximal response)."	1.28	Relationship between spontaneous dyspnoea and lability of airway obstruction in asthma. ( Lockhart, A; Marsac, J; Peiffer, C; Razzouk, H; Toumi, M, 1992)

Research

Studies (165)

Authors

Clinical Trials (8)

Trial Overview

Trial Outcomes

Absolute Change of Forced Expiratory Volume in 1 Second (FEV1) After Bronchodilators

Timeframe	Studies, this research(%)	All Research%
pre-1990	72 (43.64)	18.7374
1990's	41 (24.85)	18.2507
2000's	29 (17.58)	29.6817
2010's	23 (13.94)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Gelb, AF	1
Yamamoto, A	1
Verbeken, EK	1
Schein, MJ	1
Moridzadeh, R	1
Tran, D	1
Fraser, C	1
Barbers, R	1
Elatre, W	1
Koss, MN	1
Glassy, EF	1
Nadel, JA	1
Rahmel, T	1
Koniusch, A	1
Schwertner, M	1
Oprea, G	1
Adamzik, M	1
Nowak, H	1
Johnson, J	1
Johnson, SR	1
Carroll, CL	1
Sala, KA	1
Yang, J	1
Stanton, J	1
Wang, L	1
Beckert, L	1
Frampton, C	1
Burton, D	1
Swanney, MP	1
Tashkin, DP	2
Chipps, BE	1
Trudo, F	1
Zangrilli, JG	1
Ioan, I	2
Coutier, L	2
Bonabel, C	2
Demoulin, B	2
Marchal, F	3
Schweitzer, C	3
Varechova, S	2
Maneechotesuwan, K	1
Assawabhumi, J	1
Rattanasaengloet, K	1
Suthamsmai, T	1
Pipopsuthipaiboon, S	1
Udompunturak, S	1
Ozkaya, S	1
Dirican, A	1
Kaya, SO	1
Karanfil, RC	1
Bayrak, MG	1
Bostancı, O	1
Ece, F	1
Albrecht, J	1
Fingleton, J	1
Travers, J	1
Williams, M	1
Charles, T	1
Bowles, D	1
Strik, R	1
Shirtcliffe, P	1
Weatherall, M	1
Beasley, R	1
Hansen, M	1
Meckler, G	1
Lambert, W	1
Dickinson, C	1
Dickinson, K	1
Guise, JM	1
Müller, V	1
Gálffy, G	1
Orosz, M	1
Kováts, Z	1
Odler, B	1
Selroos, O	1
Tamási, L	1
Neininger, MP	1
Bertsche, T	1
Sarhan, HA	1
El-Garhy, OH	1
Ali, MA	1
Youssef, NA	1
Vilozni, D	1
Hakim, F	1
Livnat, G	1
Ofek, M	1
Bar-Yoseph, R	1
Bentur, L	1
Sterner, JB	1
Zanders, TB	1
Morris, MJ	1
Cancio, LC	1
Angulo, M	1
Taranto, E	1
Soto, JP	1
Malacrida, L	1
Nin, N	1
Hurtado, FJ	1
Píriz, H	1
Borrill, Z	1
Roy, K	1
Kolsum, U	1
Southworth, T	1
Vestbo, J	2
Singh, D	1
Veiga, J	1
Lopes, AJ	1
Jansen, JM	1
de Melo, PL	1
van Noord, JA	1
Aumann, JL	1
Janssens, E	1
Smeets, JJ	1
Zaagsma, J	1
Mueller, A	1
Cornelissen, PJ	1
Deesomchok, A	1
Webb, KA	1
Forkert, L	1
Lam, YM	1
Ofir, D	1
Jensen, D	1
O'Donnell, DE	1
Bertin, FR	1
Ivester, KM	1
Couëtil, LL	1
Miranda, AD	1
Valdez, TA	1
Pereira, KD	1
Dahlén, B	1
Gómez, FP	1
Casas, A	1
Howarth, PH	1
Dahlén, SE	1
Rodriguez-Roisin, R	1
Mackenzie, SD	1
Blois, S	1
Hayes, G	1
Vince, AR	1
Tamagaki, G	1
Kanazawa, H	1
Hirata, K	1
Moreau-Colson, C	1
Prieto, L	1
Gutiérrez, V	1
Cervera, A	1
Liñana, J	1
Saldien, V	1
Coppejans, HC	1
Vercauteren, MP	1
Corthouts, B	1
Van de Heyning, P	1
Jorens, PG	1
Silvestri, M	1
Sabatini, F	1
Sale, R	1
Defilippi, AC	1
Fregonese, L	1
Battistini, E	1
Biraghi, MG	1
Rossi, GA	1
Lindqvist, A	1
Karjalainen, EM	1
Laitinen, LA	1
Kava, T	1
Altraja, A	1
Pulkkinen, M	1
Halme, M	1
Laitinen, A	1
Cazzola, M	1
Matera, MG	1
Zühlke, IE	1
Kanniess, F	1
Richter, K	1
Nielsen-Gode, D	1
Böhme, S	1
Jörres, RA	1
Magnussen, H	1
Robin, B	1
Kim, YJ	1
Huth, J	1
Klocksieben, J	1
Torres, M	1
Tepper, RS	1
Castile, RG	1
Solway, J	1
Hershenson, MB	1
Goldstein-Filbrun, A	1
Tomari, S	1
Matsuse, H	1
Machida, I	1
Kondo, Y	1
Kawano, T	1
Obase, Y	1
Fukushima, C	1
Shimoda, T	1
Kohno, S	1
Silvanus, MT	1
Groeben, H	1
Peters, J	1
Lødrup Carlsen, KC	1
Pettersen, M	1
Carlsen, KH	1
Ezzahir, N	1
Leske, V	1
Peiffer, C	2
Trang, H	1
Bussamra, MH	1
Cukier, A	1
Stelmach, R	1
Rodrigues, JC	1
Tamura, G	1
Suda, Y	1
Thomas, MR	1
Rafferty, GF	1
Blowes, R	1
Peacock, JL	1
Marlow, N	1
Calvert, S	1
Milner, A	1
Greenough, A	1
Venkataraman, ST	1
Zagdańska, R	1
Grzelewska-Rzymowska, I	1
Rabinovitch, N	1
Zhang, L	1
Gelfand, EW	1
Santillanes, G	1
Gausche-Hill, M	1
Sosa, B	1
Lindberg, A	1
Szalai, Z	1
Pullerits, T	1
Radeczky, E	1
Dyson, AJ	2
Mackay, AD	1
Packe, GE	1
Cayton, RM	1
Mashhoudi, N	1
Kaik, G	1
Kaik, B	1
Laggner, A	1
Firstater, E	1
Mizrachi, E	1
Topilsky, M	1
Giulekas, D	1
Tsakalos, N	1
Christaki-Kukuriku, P	1
Kotsopoulos, T	1
Antoniou, D	1
Carmichael, J	1
Paterson, IC	1
Diaz, P	1
Crompton, GK	2
Kay, AB	1
Grant, IW	1
Hughes, D	1
Mindorff, C	1
Levison, H	1
Dalén, G	1
Kjellman, B	1
Emslander, HP	1
Baronti, A	1
Grieco, A	1
Vibelli, C	1
Surovov, IuA	1
Sil'vestrov, VP	1
Pakulin, IA	1
Sahay, JN	1
Chatterjee, SS	1
Ormerod, LP	1
Thomson, RA	1
Anderson, CM	1
Stableforth, DE	1
Congleton, J	1
Muers, MF	1
Malo, JL	1
L'Archevêque, J	1
Ghezzo, H	1
Cartier, A	1
Fergusson, RJ	1
Stewart, CM	1
Wathen, CG	1
Moffat, R	1
Verberne, AA	1
Hop, WC	1
Bos, AB	1
Kerrebijn, KF	2
Hoshiko, K	1
Morley, J	1
Lundback, B	1
Rawlinson, DW	1
Palmer, JB	1
Clough, JB	1
Starke, ID	1
Luce, P	1
Malerba, M	1
Boni, E	1
Tantucci, C	1
Filippi, B	1
Romagnoni, G	1
Grassi, V	1
Frey, U	2
Schibler, A	1
Kraemer, R	2
Emerman, CL	1
Cydulka, RK	1
Apter, AJ	1
Affleck, G	1
Reisine, ST	1
Tennen, HA	1
Barrows, E	1
Wells, M	1
Willard, A	1
ZuWallack, RL	1
Weersink, EJ	1
van Zomeren, EH	1
Koëter, GH	2
Postma, DS	2
Lin, RY	1
Pesola, GR	1
Westfal, RE	1
Bakalchuk, L	1
Freyberg, CW	1
Cataquet, D	1
Heyl, GT	1
Ragg, MD	1
Nour, MM	1
Mustafa, KY	1
Mousa, K	1
Abul, AT	1
Shuhaibar, H	1
Yousif, AM	1
Carlsson, LG	1
Arweström, E	1
Friberg, K	1
Källén, A	1
Lunde, H	1
Löfdahl, CG	2
Moy, ML	1
Lantin, ML	1
Harver, A	1
Schwartzstein, RM	1
Pellegrino, R	1
Rodarte, JR	1
Brusasco, V	1
Mellén, A	1
Arvidsson, P	1
Palmqvist, M	1
Lötvall, J	1
Brand, PL	1
Duiverman, EJ	1
Waalkens, HJ	1
van Essen-Zandvliet, EE	1
Derksen, FJ	1
Olszewski, MA	1
Robinson, NE	1
Berney, C	1
Hakala, JE	2
Matson, CJ	2
Ruth, DT	1
Rush, BR	2
Hoskinson, JJ	1
Davis, EG	1
Walton, JS	1
Fears, R	1
Burt, N	1
Dorman, BH	1
Hancox, RJ	1
Aldridge, RE	1
Cowan, JO	1
Flannery, EM	1
Herbison, GP	1
McLachlan, CR	1
Town, GI	1
Taylor, DR	1
Fink, J	1
Dhand, R	1
Manthous, CA	1
Lee, T	1
Dennis, S	1
Ziebach, R	1
Pietsch-Breitfeld, B	1
Bichler, M	1
Busch, A	1
Riethmüller, J	1
Stern, M	1
Henrikson, SL	1
Marlin, GE	3
Hartnett, BJ	1
Berend, N	2
Schultze-Werninghaus, G	1
Gonsior, E	1
Meier-Sydow, J	1
Madsen, BW	1
Tandon, MK	1
Paterson, JW	1
Patel, KR	1
Kerr, JW	2
Anderson, SD	1
Silverman, M	1
König, P	2
Godfrey, S	3
Gayrard, P	1
Orehek, J	1
Charpin, J	1
Sly, RM	1
Schindl, R	1
Kamburoff, PL	2
Prime, FJ	3
Schmidt, OP	1
Campbell, IA	3
Whitsett, TL	1
Simonsson, BG	1
Arvidsson, I	1
Haldeborg, M	1
Månsson, A	1
Webster, J	1
Pierce, RJ	1
Allen, CJ	1
Campbell, AH	1
Maneksha, S	2
Knoop, U	1
Nogrady, SG	1
Evans, WV	1
Davies, BH	2
Baur, X	1
Fruhmann, G	1
Lidington, RE	1
Cotton, DJ	1
Graham, BL	1
Dosman, JA	1
Dash, CH	3
McHardy, GJ	2
Shotter, MV	2
Cockcroft, DW	1
Donevan, RE	1
Copland, GM	1
Perko, V	1
Falaschi, C	1
Rubin, AH	1
Mansur, A	1
Schey, G	1
Shahor, Y	1
Bruderman, I	1
Freitag, A	1
Spiro, SG	1
Minette, A	1
Petrie, GR	1
Palmer, KN	2
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Radcliffe, S	1
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Graham, JD	1
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Marsac, J	1
Lockhart, A	1
Flurkey, HG	1
Gromova, OA	1
Gusel', VA	1
Waterhouse, JC	1
Simmons, JL	1
Wray, H	1
Howard, P	1
Gaddy, JN	1
Margolskee, DJ	1
Bush, RK	1
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Dijkman, JH	1
Sterk, PJ	1
Tokuyama, K	1
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Riedler, J	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap[NCT03263130]		60 participants (Anticipated)	Observational [Patient Registry]	2017-01-01	Recruiting
Evaluation of Mechanism(s)Limiting Expiratory Airflow in Chronic, Stable Asthmatics Who Are Non-smokers[NCT01225913]	Phase 4	50 participants (Anticipated)	Interventional	2007-10-31	Recruiting
Evaluation of Mechanism(s)Limiting Expiratory Airflow in Chronic, Stable Asthmatics Who Are Non-smokers[NCT00576069]		60 participants (Anticipated)	Observational	2007-10-25	Recruiting
A 12 Week, Randomized, Double-blind, Double-dummy, Placebo-controlled Trial of Symbicort TM (160/4.5mcg) Versus Its Mono-products (Budesonide and Formoterol) in Adolescents (at Least 12 Years of Age) and Adults With Asthma - SPRUCE 160/4.5[NCT00652002]	Phase 3	450 participants (Anticipated)	Interventional	2002-07-31	Completed
Comparison of Doses of Nebulized Magnesium Sulphate as an Adjuvant Treatment With Salbutamol in Children With Status Asthmaticus[NCT04929626]	Phase 1	126 participants (Actual)	Interventional	2022-01-01	Completed
Static Lung Hyperinflation and Sympathetic Nerve Activity-Associated Large Artery Stiffness in COPD Patients[NCT03611699]	Phase 4	15 participants (Actual)	Interventional	2019-01-24	Completed
Is the Exhaled Nitric Oxide in Infants a Predictive Marker of Asthma?[NCT01239199]		86 participants (Actual)	Interventional	2010-01-31	Completed
Acute Bronchodilator Responsiveness in Obliterative Bronchiolitis (OB) Following Hematopoietic Stem Cell Transplantation[NCT01112241]	Phase 4	17 participants (Actual)	Interventional	2010-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Following albuterol plus tiotropium inhalation, FEV1 increments ≥0.20 liters (L) as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to the American Thoracic Society-European Respiratory Society standard criteria [Pellegrino et al. Eur Respir J 2005; 26: 948-968]. They were calculated as follows: [FEV1 (L) after bronchodilators - FEV1 (L) before bronchodilators]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Absolute Change of Forced Vital Capacity (FVC) After Bronchodilators

Intervention	absolute positive change (liters) (Mean)
	Responsives to bronchodilators (n=4)	Unresponsives to bronchodilators (n=13)
Albuterol Plus Tiotropium	0.26	0.12

Following albuterol plus tiotropium inhalation, FVC increments ≥0.20 liters (L) compared with baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to the American Thoracic Society-European Respiratory Society standard criteria [Pellegrino et al. Eur Respir J 2005; 26: 948-968]. They were calculated as follows: [FVC (L) after bronchodilators - FVC (L) before bronchodilators]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Absolute Change of Functional Residual Capacity (FRC) After Bronchodilators

Intervention	absolute positive change (liters) (Mean)
	Responsives to bronchodilators (n=5)	Unresponsives to bronchodilators (n=12)
Albuterol Plus Tiotropium	0.65	0.07

Following albuterol plus tiotropium inhalation, FRC decrements ≥0.30 liters (L) as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to O'Donnell et al. [Eur Respir J 2001; 18: 914-920]. They were calculated as follows: [FRC (L), before bronchodilators - FRC (L) after bronchodilators]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Absolute Change of Residual Volume (RV) After Bronchodilators

Intervention	absolute negative change (liters) (Mean)
	Responsives to bronchodilators (n=4)	Unresponsives to bronchodilators (n=13)
Albuterol Plus Tiotropium	0.78	0.07

Following albuterol plus tiotropium inhalation, RV decrements ≥0.30 liters (L) as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to O'Donnell et al. [Eur Respir J 2001; 18: 914-920]. They were calculated as follows: [RV (L), before bronchodilators - RV (L) after bronchodilators]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Per Cent Change of Forced Expiratory Volume in 1 Second (FEV1) After Bronchodilators

Intervention	absolute negative change (liters) (Mean)
	Responsives to bronchodilators (n=8)	Unresponsives to bronchodilators (n=9)
Albuterol Plus Tiotropium	0.65	0.00

Following albuterol plus tiotropium inhalation, FEV1 increments ≥12 per cent as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to the American Thoracic Society-European Respiratory Society standard criteria [Pellegrino et al. Eur Respir J 2005; 26: 948-968]. They were calculated as follows: [FEV1, expressed in liters (L), after bronchodilators - FEV1 (L) before bronchodilators/FEV1 (L) before bronchodilators x 100]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Per Cent Change of Forced Vital Capacity (FVC) After Bronchodilators

Intervention	per cent positive change (Mean)
	Responsives to bronchodilators (n=4)	Unresponsives to bronchodilators (n=13)
Albuterol Plus Tiotropium	14	7

Following albuterol plus tiotropium inhalation, FVC increments ≥12 per cent as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to the American Thoracic Society-European Respiratory Society standard criteria [Pellegrino et al. Eur Respir J 2005; 26: 948-968]. They were calculated as follows: [FVC, expressed in liters (L), after bronchodilators - FVC (L) before bronchodilators/FVC (L) before bronchodilators x 100]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Per Cent Change of Functional Residual Capacity (FRC) After Bronchodilators

Intervention	per cent positive change (Mean)
	Responsives to bronchodilators (n=5)	Unresponsives to bronchodilators (n=12)
Albuterol Plus Tiotropium	24	2

Following albuterol plus tiotropium inhalation, FRC decrements ≥10 per cent as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to O'Donnell et al. [Eur Respir J 2001; 18: 914-920]. They were calculated as follows: [FRC, expressed in liters (L), before bronchodilators - FRC (L) after bronchodilators/FRC (L) after bronchodilators x 100]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Per Cent Change of Instantaneous Maximal Forced Expiratory Flow (V'Max) After Bronchodilators

Intervention	per cent negative change (Mean)
	Responsives to bronchodilators (n=4)	Unresponsives to bronchodilators (n=13)
Albuterol Plus Tiotropium	16	2

Following albuterol plus tiotropium inhalation, V'max increments ≥40 per cent as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to Pellegrino et al. [Chest 1998; 114:1607-1612]. They were calculated as follows: [V'max, expressed in liters.second-1 (L.s-1), after bronchodilators - V'max (L.s-1) before bronchodilators/V'max (L.s-1) before bronchodilators x 100]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Per Cent Change of Partial Forced Expiratory Flow (V'Part) After Bronchodilators

Intervention	per cent positive change (Mean)
	Responsives to bronchodilators (n=4)	Unresponsives to bronchodilators (n=13)
Albuterol Plus Tiotropium	66	14

Following albuterol plus tiotropium inhalation, V'part increments ≥40 per cent as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to Pellegrino et al. [Chest 1998; 114:1607-1612]. They were calculated as follows: [V'part, expressed in liters.second-1 (L.s-1), after bronchodilators - V'part (L.s-1) before bronchodilators/V'part (L.s-1) before bronchodilators x 100]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Per Cent Change of Residual Volume (RV) After Bronchodilators

Intervention	per cent positive change (Mean)
	Responsives to bronchodilators (n=9)	Unresponsives to bronchodilators (n=8)
Albuterol Plus Tiotropium	59	17

Following albuterol plus tiotropium inhalation, RV decrements ≥10 per cent as compared to baseline, in an individual subject, were considered as evidence of response to bronchodilators, according to O'Donnell et al. [Eur Respir J 2001; 18: 914-920]. They were calculated as follows: [RV, expressed in liters (L), before bronchodilators - RV (L) after bronchodilators/RV (L) after bronchodilators x 100]. (NCT01112241)
Timeframe: Baseline and 90 min after bronchodilators

Article	Year
Evaluation of inhaled salbutamol effectiveness under supportive use of electrical impedance tomography in ventilated ICU patients: study protocol for a randomised controlled clinical trial. BMJ open, 2019, 03-12, Volume: 9, Issue:3 Topics: Administration, Inhalation; Airway Obstruction; Albuterol; Bronchodilator Agents; Chronic Disease; C	2019
Effect of salbutamol on the measurement of single-breath diffusing capacity. Respirology (Carlton, Vic.), 2013, Volume: 18, Issue:8 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Carbon Monoxide; Fema	2013
Fixed airflow obstruction in asthma: a descriptive study of patient profiles and effect on treatment responses. The Journal of asthma : official journal of the Association for the Care of Asthma, 2014, Volume: 51, Issue:6 Topics: Adolescent; Adult; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Budesonide; Child;	2014
Comparison between the effects of generic and original salmeterol/fluticasone combination (SFC) treatment on airway inflammation in stable asthmatic patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97 Suppl 3 Topics: Adult; Aged; Airway Obstruction; Albuterol; Androstadienes; Anti-Inflammatory Agents; Asthma; Cross-	2014
Treatment responsiveness of phenotypes of symptomatic airways obstruction in adults. The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:3 Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Airway Obstruction; Albuterol; Anti-As	2015
Seretide withdrawal increases airway inflammation in moderate COPD patients. European journal of clinical pharmacology, 2009, Volume: 65, Issue:11 Topics: Aged; Airway Obstruction; Albuterol; Androstadienes; Drug Combinations; Fluticasone-Salmeterol Drug	2009
Combining tiotropium and salmeterol in COPD: Effects on airflow obstruction and symptoms. Respiratory medicine, 2010, Volume: 104, Issue:7 Topics: Adult; Airway Obstruction; Albuterol; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method	2010
Comparative efficacy of inhaled albuterol between two hand-held delivery devices in horses with recurrent airway obstruction. Equine veterinary journal, 2011, Volume: 43, Issue:4 Topics: Administration, Inhalation; Airway Obstruction; Albuterol; Animals; Bronchodilator Agents; Female; H	2011
Salbutamol but not ipratropium abolishes leukotriene D4-induced gas exchange abnormalities in asthma. European journal of clinical pharmacology, 2012, Volume: 68, Issue:10 Topics: Administration, Inhalation; Adult; Airway Obstruction; Albuterol; Arteries; Asthma; Bronchoconstrict	2012
Association of airway pentosidine levels with bronchodilator response mediated by salbutamol administration in asthmatic patients. Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:6 Topics: Adult; Airway Obstruction; Albuterol; Arginine; Asthma; Biomarkers; Bronchial Provocation Tests; Bro	2012
Salmeterol resolves airway obstruction but does not possess anti-eosinophil efficacy in newly diagnosed asthma: a randomized, double-blind, parallel group biopsy study comparing the effects of salmeterol, fluticasone propionate, and disodium cromoglycate. The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:1 Topics: Adult; Airway Obstruction; Albuterol; Androstadienes; Asthma; Biopsy; Bronchi; Cromolyn Sodium; Doub	2003
Montelukast attenuates the airway response to hypertonic saline in moderate-to-severe COPD. The European respiratory journal, 2003, Volume: 22, Issue:6 Topics: Acetates; Administration, Inhalation; Administration, Oral; Aged; Airway Obstruction; Albuterol; Bro	2003
Pulmonary function in bronchopulmonary dysplasia. Pediatric pulmonology, 2004, Volume: 37, Issue:3 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Bronchopulmonary Dysplasia; Child, Preschool;	2004
Corticosteroids and inhaled salbutamol in patients with reversible airway obstruction markedly decrease the incidence of bronchospasm after tracheal intubation. Anesthesiology, 2004, Volume: 100, Issue:5 Topics: Administration, Inhalation; Adrenal Cortex Hormones; Aged; Airway Obstruction; Albuterol; Analysis o	2004
Relevance of a portable spirometer for detection of small airways obstruction. Pediatric pulmonology, 2005, Volume: 39, Issue:2 Topics: Administration, Inhalation; Adolescent; Airway Obstruction; Albuterol; Bronchodilator Agents; Child;	2005
Evaluation of the magnitude of the bronchodilator response in children and adolescents with asthma. Chest, 2005, Volume: 127, Issue:2 Topics: Adolescent; Adult; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bronchodilator Agents;	2005
Fast onset of effect of budesonide/formoterol versus salmeterol/fluticasone and salbutamol in patients with chronic obstructive pulmonary disease and reversible airway obstruction. Respirology (Carlton, Vic.), 2007, Volume: 12, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Aged; Airway Obstruction; Albuterol; Androstadienes; Anti-Asthmatic	2007
Two oral beta-adrenergic stimulant drugs, pirbuterol and salbutamol, in reversible airway obstruction. British journal of diseases of the chest, 1980, Volume: 74, Issue:1 Topics: Adolescent; Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Bronchodilator Agents; Clinical	1980
[Clinical pharmacological trials of a new metered dose inhaler, IK-6, a combination of the bronchodilators fenoterol and ipratropium bromide (author's transl)]. Wiener medizinische Wochenschrift (1946), 1980, Jun-15, Volume: 130, Issue:11 Topics: Aerosols; Airway Obstruction; Albuterol; Asthma; Atropine Derivatives; Drug Combinations; Ethanolami	1980
The immediate effect of sodium cromoglycate on the airway. Annals of allergy, 1982, Volume: 48, Issue:1 Topics: Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Child; Cromolyn Sodium; Female; Humans	1982
A comparison between inhaled clenbuterol and salbutamol in chronic bronchitis with reversible airway obstruction. European journal of respiratory diseases, 1980, Volume: 61, Issue:3 Topics: Aerosols; Aged; Airway Obstruction; Albuterol; Bronchitis; Chronic Disease; Clenbuterol; Clinical Tr	1980
A comparative trial of combination therapy in obstructive airways disease. Current medical research and opinion, 1980, Volume: 7, Issue:1 Topics: Adult; Aged; Airway Obstruction; Albuterol; Aminophylline; Delayed-Action Preparations; Drug Therapy	1980
The incidence of airflow obstruction in bronchial carcinoma, its relation to breathlessness, and response to bronchodilator therapy. Respiratory medicine, 1995, Volume: 89, Issue:4 Topics: Adult; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Carcinoma, Bronchogenic; Drug Com	1995
The reversibility of airway obstruction to an inhaled beta 2-adrenergic agent is less satisfactory after methacholine testing in asthmatic subjects. Chest, 1995, Volume: 107, Issue:5 Topics: Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchial Provocation Tests; Double-Blind Method	1995
Effect of a single dose of inhaled salmeterol on baseline airway caliber and methacholine-induced airway obstruction in asthmatic children. The Journal of allergy and clinical immunology, 1993, Volume: 91, Issue:1 Pt 1 Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Ast	1993
Twelve month comparison of salmeterol and salbutamol as dry powder formulations in asthmatic patients. European Study Group. Thorax, 1993, Volume: 48, Issue:2 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Asthma; Chemistry, Pharmaceutical; Double-Bl	1993
The efficacy and safety of inhaled salmeterol 50 microg bd in older patients with reversible airflow obstruction. Age and ageing, 1996, Volume: 25, Issue:1 Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Aged, 80 and over; Airway Obstruction; A	1996
Ineffectiveness of intravenous beta 2-agonists on improving exercise tolerance in patients with reversible chronic airway obstruction. Respiration; international review of thoracic diseases, 1996, Volume: 63, Issue:1 Topics: Adrenergic beta-Agonists; Aged; Airway Obstruction; Albuterol; Blood Gas Analysis; Chronic Disease;	1996
Effect of different albuterol dosing regimens in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Annals of emergency medicine, 1997, Volume: 29, Issue:4 Topics: Aerosols; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Female; Forced Expiratory Volu	1997
Treatment of nocturnal airway obstruction improves daytime cognitive performance in asthmatics. American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:4 Pt 1 Topics: Administration, Inhalation; Adult; Airway Obstruction; Albuterol; Androstadienes; Anti-Asthmatic Age	1997
Early parenteral corticosteroid administration in acute asthma. The American journal of emergency medicine, 1997, Volume: 15, Issue:7 Topics: Acute Disease; Adult; Aerosols; Airway Obstruction; Albuterol; Anti-Asthmatic Agents; Anti-Inflammat	1997
Reversible airway obstruction in rheumatic mitral valve disease. Respirology (Carlton, Vic.), 1998, Volume: 3, Issue:1 Topics: Adult; Airway Obstruction; Albuterol; Bronchodilator Agents; Female; Forced Expiratory Volume; Human	1998
Efficacy of cumulative doses of salbutamol administered via Turbuhaler or Diskhaler in patients with reversible airway obstruction. Allergy, 1998, Volume: 53, Issue:7 Topics: Administration, Inhalation; Adult; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Cross	1998
Assessing the reversibility of airway obstruction. Chest, 1998, Volume: 114, Issue:6 Topics: Adult; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Chronic Disease; Female; Humans;	1998
Equivalent bronchodilation with salbutamol given via pMDI or turbuhaler. American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:5 Pt 1 Topics: Adult; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Cross-Over Studies; Dose-Response	1999
Peak flow variation in childhood asthma: correlation with symptoms, airways obstruction, and hyperresponsiveness during long-term treatment with inhaled corticosteroids. Dutch CNSLD Study Group. Thorax, 1999, Volume: 54, Issue:2 Topics: Administration, Inhalation; Administration, Topical; Adolescent; Airway Obstruction; Albuterol; Anti	1999
Tolerance to beta-agonists during acute bronchoconstriction. The European respiratory journal, 1999, Volume: 14, Issue:2 Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Airway Obstruction; Albuterol; Asthma; B	1999
Bronchodilatory effects of salbutamol, ipratropium bromide, and their combination: double-blind, placebo-controlled crossover study in cystic fibrosis. Pediatric pulmonology, 2001, Volume: 31, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Airway Obstruction; Albuterol; Bronchodilat	2001
Efficacy of salmeterol xinafoate in horses with recurrent airway obstruction. Journal of the American Veterinary Medical Association, 2001, Jun-15, Volume: 218, Issue:12 Topics: Administration, Inhalation; Airway Obstruction; Albuterol; Animals; Bronchodilator Agents; Cross-Ove	2001
Comparative potencies and beta2-adrenoreceptor selectivities of rimiterol and salbutamol aerosols. British journal of clinical pharmacology, 1977, Volume: 4, Issue:1 Topics: Adult; Aerosols; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Catechols; Forced Expir	1977
[Parasympathicolytic drugs in treatment of obstructive lung diseases (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1979, Aug-03, Volume: 104, Issue:31 Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Asthma; Atropine Derivatives; Cromolyn Sodi	1979
Cross-over study of the efficacy of four beta 2-sympathomimetic bronchodilator aerosols. British journal of clinical pharmacology, 1979, Volume: 8, Issue:1 Topics: Adrenergic beta-Agonists; Adult; Aerosols; Aged; Airway Obstruction; Albuterol; Analysis of Variance	1979
Letter: Alpha-receptor-blocking drugs in bronchial asthma. Lancet (London, England), 1975, Feb-08, Volume: 1, Issue:7902 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Airway Obstruction; Airway Resistance; Albut	1975
The bronchodilator effect of NAB 365. British journal of clinical pharmacology, 1977, Volume: 4, Issue:1 Topics: Adult; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Ethan	1977
Indoramin--an alpha adrenoreceptor antagonist for airway obstruction. British journal of diseases of the chest, 1977, Volume: 71, Issue:2 Topics: Adult; Aged; Airway Obstruction; Albuterol; Clinical Trials as Topic; Drug Therapy, Combination; Fem	1977
Albuterol and ephedrine in patients with reversible obstructive airway disease. Annals of allergy, 1977, Volume: 38, Issue:6 Topics: Airway Obstruction; Albuterol; Blood Pressure; Clinical Trials as Topic; Ephedrine; Forced Expirator	1977
Treatment of airways obstruction by continuous nebulization with and without assisted ventilation. Scandinavian journal of respiratory diseases. Supplementum, 1977, Volume: 101 Topics: Aged; Airway Obstruction; Albuterol; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Inte	1977
Salbutamol by pressure-packed aerosol and by intermittent positive pressure ventilation in chronic obstructive bronchitis. British journal of diseases of the chest, 1978, Volume: 72, Issue:2 Topics: Aerosols; Aged; Airway Obstruction; Albuterol; Bronchitis; Chronic Disease; Clinical Trials as Topic	1978
A comparative study of atropine methonitrate, salbutamol, and their combination in airways obstruction. Thorax, 1979, Volume: 34, Issue:1 Topics: Aerosols; Aged; Airway Obstruction; Albuterol; Asthma; Atropine Derivatives; Clinical Trials as Topi	1979
A clinical trial of choline theophyllinate versus salbutamol with placebo control. The Journal of international medical research, 1979, Volume: 7, Issue:5 Topics: Administration, Oral; Adult; Aged; Airway Obstruction; Albuterol; Bronchodilator Agents; Choline; Cl	1979
A comparative assessment of three bronchodilator preparations in general practice. The Journal of international medical research, 1979, Volume: 7 Suppl 1 Topics: Airway Obstruction; Albuterol; Aminophylline; Delayed-Action Preparations; Humans; Peak Expiratory F	1979
A comparative crossover study of two long-acting bronchodilator preparations. Current medical research and opinion, 1976, Volume: 4, Issue:3 Topics: Adult; Airway Obstruction; Albuterol; Aminophylline; Clinical Trials as Topic; Delayed-Action Prepar	1976
Comparison of salmefamol and salbutamol in patients with chronic airways obstruction. British journal of clinical pharmacology, 1976, Volume: 3, Issue:1 Topics: Adolescent; Adult; Airway Obstruction; Albuterol; Chronic Disease; Clinical Trials as Topic; Drug Ev	1976
Carbuterol: a double-blind clinical trial comparing carbuterol and salbutamol. Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:2 Topics: Adult; Airway Obstruction; Albuterol; Asthma; Blood Pressure; Bronchitis; Bronchodilator Agents; Cli	1976
Inhibition of exercise-induced asthma by different pharmacological pathways. Thorax, 1976, Volume: 31, Issue:2 Topics: Adolescent; Airway Obstruction; Albuterol; Asthma; Atropine Derivatives; Bronchodilator Agents; Chil	1976
Comparison of aerosol ipratropium bromide and salbutamol in chronic bronchitis and asthma. British medical journal, 1975, Feb-22, Volume: 1, Issue:5955 Topics: Aerosols; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Atropine; Atropine Derivatives;	1975
Proceedings: Comparison of two bronchodilators--salmefamol and salbutamol. Tubercle, 1975, Volume: 56, Issue:2 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Clinical Trials as Topic; Ethanolamines; Human	1975
Comparison between the bronchodilator and cardiovascular effects of inhaling 0.5 mg. rimiterol ('Pulmadil') and 0.2 mg. salbutamol. Current medical research and opinion, 1975, Volume: 3, Issue:1 Topics: Adult; Aerosols; Airway Obstruction; Albuterol; Asthma; Blood Pressure; Bronchi; Bronchitis; Broncho	1975
A trial of oral delta-1-(trans)-tetrahydrocannabinol in reversible airways obstruction. Thorax, 1975, Volume: 30, Issue:1 Topics: Administration, Oral; Adult; Aged; Airway Obstruction; Albuterol; Animals; Blood Pressure; Bronchodi	1975
Comparative assessment of a new breath-actuated inhaler in patients with reversible airways obstruction. Respiration; international review of thoracic diseases, 1992, Volume: 59, Issue:3 Topics: Adult; Aged; Airway Obstruction; Albuterol; Asthma; Double-Blind Method; Forced Expiratory Volume; H	1992
Bronchodilation with a potent and selective leukotriene D4 (LTD4) receptor antagonist (MK-571) in patients with asthma. The American review of respiratory disease, 1992, Volume: 146, Issue:2 Topics: Adult; Airway Obstruction; Albuterol; Analysis of Variance; Asthma; Double-Blind Method; Drug Therap	1992
Separate and combined effects of corticosteroids and bronchodilators on airflow obstruction and airway hyperresponsiveness in asthma. The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:3 Topics: Adrenal Cortex Hormones; Adult; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bronchial	1992
Evaluation of procaterol and albuterol (salbutamol) aerosol in the treatment of asthma. Annals of allergy, 1992, Volume: 68, Issue:3 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Child; Dose-R	1992
Time course of bronchodilating effect of inhaled formoterol, a potent and long acting sympathomimetic. Thorax, 1992, Volume: 47, Issue:1 Topics: Adolescent; Adult; Airway Obstruction; Albuterol; Bronchodilator Agents; Drug Administration Schedul	1992
The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease. Thorax, 1991, Volume: 46, Issue:1 Topics: Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchoconstriction; Dose-Response Relationship,	1991
[Effects of ipratropium bromide and salbutamol on isolated lung hyperinflation in symptom-free intervals in asthmatic children]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1990, Volume: 138, Issue:3 Topics: Administration, Inhalation; Adolescent; Airway Obstruction; Albuterol; Asthma; Atropine Derivatives;	1990
[Inhalation bronchodilators in infancy--comparative study between salbutamol and ipratropium bromide]. Pneumologie (Stuttgart, Germany), 1990, Volume: 44, Issue:5 Topics: Airway Obstruction; Albuterol; Atropine Derivatives; Female; Humans; Infant; Infant, Newborn; Ipratr	1990
[The bronchodilator effect of aerosol beta-2-mimetic and anticholinergic agents in patients with chronic bronchitis]. Revue des maladies respiratoires, 1990, Volume: 7, Issue:1 Topics: Aerosols; Airway Obstruction; Albuterol; Bronchi; Bronchitis; Bronchodilator Agents; Chronic Disease	1990
The role of alpha and beta adrenoceptors in airway hyperresponsiveness to histamine. The Journal of allergy and clinical immunology, 1985, Volume: 75, Issue:3 Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Airway Obstruction; Albutero	1985
[Beta-2 specificity of bronchially active sympathomimetics using capillary laser Doppler sonography exemplified by tulobuterol]. Praxis und Klinik der Pneumologie, 1987, Volume: 41, Issue:4 Topics: Adrenergic beta-Agonists; Adult; Airway Obstruction; Albuterol; Double-Blind Method; Female; Humans;	1987
A comparison between fenoterol/ipratropium bromide combinations and salbutamol administered as nebulizer solutions assessing dose-response and duration of action. Pharmatherapeutica, 1986, Volume: 4, Issue:7 Topics: Aerosols; Aged; Airway Obstruction; Albuterol; Atropine Derivatives; Blood Pressure; Dose-Response R	1986
A comparison of oral procaterol and albuterol in reversible airflow obstruction. The American review of respiratory disease, 1988, Volume: 138, Issue:6 Topics: Administration, Oral; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Clinical Trials	1988
Bronchospasmolytic effects of salbutamol as powder inhalation in patients with reversible bronchial obstruction. Arzneimittel-Forschung, 1988, Volume: 38, Issue:10 Topics: Adult; Airway Obstruction; Albuterol; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Fem	1988
A comparison of albuterol and metaproterenol nebulizer solutions. Annals of allergy, 1987, Volume: 58, Issue:6 Topics: Adult; Aged; Airway Obstruction; Albuterol; Clinical Trials as Topic; Double-Blind Method; Humans; I	1987
Effects of the calcium antagonist tiapamil on pulmonary gas exchange in patients with chronic obstructive pulmonary disease who receive salbutamol. Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:1 Topics: Adult; Aged; Airway Obstruction; Albuterol; Double-Blind Method; Drug Evaluation; Drug Interactions;	1985
A clinical trial of long-term oral salbutamol in reversible diffuse airway obstruction. The American review of respiratory disease, 1973, Volume: 108, Issue:6 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchitis; Chronic Disease; Clinica	1973
Comparative trial of a new anticholinergic bronchodilator, Sch 1000, and salbutamol in chronic bronchitis. British medical journal, 1973, Oct-20, Volume: 4, Issue:5885 Topics: Aged; Airway Obstruction; Albuterol; Atropine; Bronchitis; Bronchodilator Agents; Chronic Disease; C	1973
The role of oral bronchodilator therapy as shown by a comparison between salbutamol and terbutaline. Current medical research and opinion, 1973, Volume: 1, Issue:9 Topics: Administration, Oral; Adult; Airway Obstruction; Albuterol; Asthma; Blood Pressure; Clinical Trials	1973
Comparison of cardiorespiratory effects of terbutaline and salbutamol aerosols in patients with reversible airways obstruction. Thorax, 1973, Volume: 28, Issue:5 Topics: Adult; Aerosols; Aged; Airway Obstruction; Albuterol; Cardiac Output; Clinical Trials as Topic; Hear	1973
A comparative trial of salbutamol and isoprenaline in asthma. Annals of clinical research, 1974, Volume: 6, Issue:2 Topics: Adult; Aerosols; Airway Obstruction; Albuterol; Asthma; Carbon Dioxide; Female; Heart Rate; Humans;	1974

Article	Year
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction. Chest, 2018, Volume: 153, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Asthma; Autopsy; Bronchodilator Agent	2018
Cross-sectional study of reversible airway obstruction in LAM: better evidence is needed for bronchodilator and inhaled steroid use. Thorax, 2019, Volume: 74, Issue:10 Topics: Administration, Inhalation; Adult; Airway Obstruction; Albuterol; Bronchodilator Agents; Cross-Secti	2019
Bronchial obstruction and reversibility in children: inspiratory or expiratory resistance? The European respiratory journal, 2014, Volume: 44, Issue:1 Topics: Airway Obstruction; Albuterol; Asthma; Bronchial Diseases; Bronchodilator Agents; Case-Control Studi	2014
The relationship between early reversibility test and maximal inspiratory pressure in patients with airway obstruction. International journal of chronic obstructive pulmonary disease, 2014, Volume: 9 Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Albuterol; Bronchodilator Agents; Forced Expirat	2014
Airway obstruction, upper airway artifact and response to bronchodilator in asthmatic and healthy children. Pediatric pulmonology, 2015, Volume: 50, Issue:11 Topics: Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bronchodilator Agents; Child; Female; Huma	2015
Paramedic assessment and treatment of upper airway obstruction in pediatric patients: an exploratory analysis by the Children's Safety Initiative-Emergency Medical Services. The American journal of emergency medicine, 2016, Volume: 34, Issue:3 Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Agonists; Airway Obstruction; Albu	2016
Characteristics of reversible and nonreversible COPD and asthma and COPD overlap syndrome patients: an analysis of salbutamol Easyhaler data. International journal of chronic obstructive pulmonary disease, 2016, Volume: 11 Topics: Administration, Inhalation; Aged; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Cros	2016
[Risk reduction by pharmaceutical intervention. Medication management using the example of salbutamol]. Medizinische Monatsschrift fur Pharmazeuten, 2016, Volume: 39, Issue:1 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Child; Humans; Medication Therapy Management;	2016
The efficacy of nebulized magnesium sulfate alone and in combination with salbutamol in acute asthma. Drug design, development and therapy, 2016, Volume: 10 Topics: Acute Disease; Administration, Inhalation; Airway Obstruction; Albuterol; Asthma; Double-Blind Metho	2016
Assessment of Airway Bronchodilation by Spirometry Compared to Airway Obstruction in Young Children with Asthma. Canadian respiratory journal, 2016, Volume: 2016 Topics: Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Child; Child, Preschool; Female; Human	2016
[Salbutamol improves diaphragmatic contractility in chronic airway obstruction]. Archivos de bronconeumologia, 2009, Volume: 45, Issue:5 Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Alkalosis; Animals; Chronic Disease; Diaphr	2009
Effects of airway obstruction on albuterol-mediated variations in the resistive and elastic properties of the respiratory system of patients with asthma. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2009, Volume: 35, Issue:7 Topics: Adolescent; Adult; Aged; Airway Obstruction; Airway Resistance; Albuterol; Analysis of Variance; Ast	2009
Lung hyperinflation and its reversibility in patients with airway obstruction of varying severity. COPD, 2010, Volume: 7, Issue:6 Topics: Aged; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Lung Volume Meas	2010
Bacterial tracheitis: a varied entity. Pediatric emergency care, 2011, Volume: 27, Issue:10 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Bronchoscopy; Child; Exudates and Transudates;	2011
Oral thermal injury associated with puncture of a salbutamol metered-dose inhaler in a dog. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2012, Volume: 22, Issue:4 Topics: Airway Obstruction; Albuterol; Animals; Burns; Dog Diseases; Dogs; Female; Metered Dose Inhalers; Mo	2012
Respiratory impedance response to a deep inhalation in asthmatic children with spontaneous airway obstruction. The European respiratory journal, 2002, Volume: 19, Issue:6 Topics: Adolescent; Airway Obstruction; Airway Resistance; Albuterol; Analysis of Variance; Asthma; Bronchod	2002
Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness. Journal of investigational allergology & clinical immunology, 2002, Volume: 12, Issue:2 Topics: Acetaldehyde; Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Airway Obstruc	2002
Acute respiratory distress after upper airway obstruction following palatoplasty. International journal of pediatric otorhinolaryngology, 2003, Volume: 67, Issue:4 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Child; Diuretics; Furosemide; Humans; Male; Pa	2003
Correlations between exhaled nitric oxide levels, blood eosinophilia, and airway obstruction reversibility in childhood asthma are detectable only in atopic individuals. Pediatric pulmonology, 2003, Volume: 35, Issue:5 Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Asthma; Breath Tests; Bronchodilator Agents	2003
Three 20-minute interspaced salbutamol inhalations as a test for the diagnosis of reversible airflow limitation in adult asthmatics. The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:1 Topics: Administration, Inhalation; Administration, Oral; Aged; Airway Obstruction; Albuterol; Anti-Inflamma	2004
Is bronchodilator response in 2-yr-old children associated with asthma risk factors? Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2004, Volume: 15, Issue:4 Topics: Administration, Inhalation; Adrenal Cortex Hormones; Airway Obstruction; Albuterol; Bronchodilator A	2004
Images in clinical medicine. Airway dilatation after inhalation of a beta-agonist. The New England journal of medicine, 2005, Apr-14, Volume: 352, Issue:15 Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Airway Obstruction; Albuterol; Asthma;	2005
Plethysmograph and interrupter resistance measurements in prematurely born young children. Archives of disease in childhood. Fetal and neonatal edition, 2006, Volume: 91, Issue:3 Topics: Airway Obstruction; Airway Resistance; Albuterol; Bronchodilator Agents; Functional Residual Capacit	2006
[FEV1 after three years of observation in patients with bronchial asthma and patients with chronic obstructive pulmonary disease]. Pneumonologia i alergologia polska, 2005, Volume: 73, Issue:2 Topics: Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Female; Follow-Up Studies	2005
Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction. The Journal of allergy and clinical immunology, 2006, Volume: 118, Issue:3 Topics: Acetates; Adolescent; Airway Obstruction; Albuterol; Asthma; Child; Chronic Disease; Cyclopropanes;	2006
Preparedness of selected pediatric offices to respond to critical emergencies in children. Pediatric emergency care, 2006, Volume: 22, Issue:11 Topics: Airway Obstruction; Albuterol; Anticonvulsants; California; Child; Child, Preschool; Data Collection	2006
Nebulised ipratropium bromide and salbutamol causing closed-angle glaucoma. Lancet (London, England), 1984, Sep-22, Volume: 2, Issue:8404 Topics: Acute Disease; Aerosols; Aged; Airway Obstruction; Albuterol; Atropine Derivatives; Drug Therapy, Co	1984
The effect of vagolytic drugs on airway obstruction in patients with bronchial asthma. Annals of allergy, 1981, Volume: 46, Issue:6 Topics: Airway Obstruction; Albuterol; Asthma; Atropine; Forced Expiratory Volume; Humans; Ipratropium; Maxi	1981
Safety and efficacy of salbutamol aerosol on Dermatophagoides farinae induced bronchospasm in asthmatic patients. Annals of allergy, 1984, Volume: 53, Issue:5 Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Airway Obstruction; Albuterol; Antigens; As	1984
Corticosteroid resistance in chronic asthma. British medical journal (Clinical research ed.), 1981, May-02, Volume: 282, Issue:6274 Topics: Adrenal Cortex Hormones; Adult; Airway Obstruction; Albuterol; Asthma; Bronchi; Chronic Disease; Cir	1981
MMEF or FEV1 in estimating bronchial obstruction in asthmatic children. Allergy, 1983, Volume: 38, Issue:3 Topics: Administration, Intranasal; Adolescent; Airway Obstruction; Albuterol; Asthma; Bronchospirometry; Ch	1983
[Use of fiber bronchoscopy in emergency medicine]. Der Internist, 1980, Volume: 21, Issue:1 Topics: Airway Obstruction; Albuterol; Beclomethasone; Bronchoscopy; Emergencies; Female; Fiber Optic Techno	1980
[Significance of reversibility of obstructive respiratory disorders in bronchial asthma for prognosis of the effectiveness of treatment]. Terapevticheskii arkhiv, 1980, Volume: 52, Issue:3 Topics: Aerosols; Airway Obstruction; Albuterol; Asthma; Humans; Prognosis	1980
Reversible airway obstruction in cystic fibrosis. Thorax, 1980, Volume: 35, Issue:10 Topics: Adolescent; Age Factors; Airway Obstruction; Albuterol; Asthma; Child; Child, Preschool; Cystic Fibr	1980
Effectiveness of nebulised salbutamol administered in ambulances to patients with severe acute asthma. Thorax, 1995, Volume: 50, Issue:1 Topics: Acute Disease; Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Airway Obstru	1995
Exacerbation of airway hyperreactivity by (+/-)salbutamol in sensitized guinea pig. Japanese journal of pharmacology, 1993, Volume: 63, Issue:2 Topics: Airway Obstruction; Albuterol; Animals; Bronchial Hyperreactivity; Guinea Pigs; Male; Ovalbumin; Res	1993
Bronchodilators in infancy. Thorax, 1993, Volume: 48, Issue:4 Topics: Airway Obstruction; Albuterol; Child, Preschool; Humans; Infant; Infant, Newborn; Respiratory Sounds	1993
Pressure oscillations after flow interruption in relation to lung mechanics. Respiration physiology, 1995, Volume: 102, Issue:2-3 Topics: Adolescent; Adult; Airway Obstruction; Airway Resistance; Albuterol; Carbachol; Child; Humans; Lung;	1995
Oscillatory pressure transients after flow interruption during bronchial challenge test in children. The European respiratory journal, 1997, Volume: 10, Issue:1 Topics: Acoustics; Adolescent; Air; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bronchial Prov	1997
Perception of airway obstruction in asthma: sequential daily analyses of symptoms, peak expiratory flow rate, and mood. The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:5 Topics: Adolescent; Adult; Affect; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Female; Hum	1997
Choking after inhaling a foreign body through a Ventolin puffer. The Medical journal of Australia, 1998, May-04, Volume: 168, Issue:9 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Foreign Bodies; Humans; Nebulizers and Vaporiz	1998
Language of dyspnea in assessment of patients with acute asthma treated with nebulized albuterol. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3 Topics: Acute Disease; Administration, Inhalation; Adult; Airway Obstruction; Albuterol; Asthma; Bronchodila	1998
Aerosolized albuterol sulfate used as a bronchodilator in horses with recurrent airway obstruction. American journal of veterinary research, 1999, Volume: 60, Issue:6 Topics: Administration, Inhalation; Aerosols; Airway Obstruction; Albuterol; Animals; Bronchodilator Agents;	1999
Pulmonary distribution of aerosolized technetium Tc 99m pentetate after administration of a single dose of aerosolized albuterol sulfate in horses with recurrent airway obstruction. American journal of veterinary research, 1999, Volume: 60, Issue:6 Topics: Administration, Inhalation; Aerosols; Airway Obstruction; Albuterol; Animals; Bronchodilator Agents;	1999
Intraoperative breathing circuit obstruction caused by albuterol nebulization. Anesthesia and analgesia, 1999, Volume: 89, Issue:3 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Child; Epilepsy; Female; Humans; Hysterectomy;	1999
Short-acting beta2-agonists. Lancet (London, England), 2000, Sep-09, Volume: 356, Issue:9233 Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Airway Obstruction; Albuterol; Asthma; Bro	2000
Exercise-induced asthma. British journal of diseases of the chest, 1975, Volume: 69, Issue:1 Topics: Acidosis, Respiratory; Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Airway Obstruction; Air	1975
[Induced beta-adrenergic stimulation and blockade in asthma bronchomotor effects (author's transl)]. Respiration; international review of thoracic diseases, 1975, Volume: 32, Issue:4 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Obstruction; Airway Resistance; Albute	1975
Effect of beta-adrenoreceptor stimulants on exercise-induced asthma. Pediatrics, 1975, Volume: 56, Issue:5 pt-2 sup Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Asthma; Child; Epinephrine; Humans; Isoetha	1975
[Broncholytic aerosols; with special attention to juvenile patients]. Wiener medizinische Wochenschrift. Supplement, 1978, Volume: 51 Topics: Adolescent; Aerosols; Age Factors; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Body He	1978
[Management of severe asthma in childhood (author's transl)]. Monatsschrift fur Kinderheilkunde, 1977, Volume: 125, Issue:11 Topics: Acetylcysteine; Age Factors; Airway Obstruction; Albuterol; Aminophylline; Asthma; Bromhexine; Child	1977
Reversibility of airways obstruction in bronchiectasis. Thorax, 1978, Volume: 33, Issue:5 Topics: Adult; Airway Obstruction; Albuterol; Bronchiectasis; Female; Humans; Hypersensitivity; Male; Middle	1978
[Pathogenesis and prevention of exercise-induced asthma]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Airway Obstruction; Albuterol; Asthma; Humans; Physical Exertion	1978
Peripheral airways obstruction in patients with rhinitis. Annals of allergy, 1979, Volume: 42, Issue:1 Topics: Adult; Airway Obstruction; Albuterol; Female; Forced Expiratory Volume; Humans; Male; Maximal Midexp	1979
[Clinical and functional aspects of obstructive respiratory syndromes following administration of a single dose of salbutamol in aerosol form]. Minerva medica, 1977, Feb-18, Volume: 68, Issue:8 Topics: Aerosols; Aged; Airway Obstruction; Albuterol; Chronic Disease; Female; Humans; Male; Maximal Expira	1977
Reversibility of small airway obstruction after therapy with salbutamol. Studies in asymptomatic asthmatic patients after inhalation of pressurized aerosol. Chest, 1977, Volume: 71, Issue:4 Topics: Adolescent; Adult; Aerosols; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Female; Force	1977
Aminophylline injection and theophylline tablets: Acute response in partially reversible chronic airway obstruction. The Medical journal of Australia, 1976, Apr-03, Volume: 1, Issue:14 Topics: Adult; Airway Obstruction; Albuterol; Aminophylline; Chronic Disease; Female; Humans; Injections, In	1976
Nocturnal asthma and sudden death. American family physician, 1976, Volume: 14, Issue:6 Topics: Adolescent; Adult; Airway Obstruction; Albuterol; Asthma; Bronchodilator Agents; Circadian Rhythm; D	1976
[Epidemiological contribution to the etiology of chronic bronchitis. III. Standardization of methods suitable for the study of bronchial hyperreactivity and allergy in epidemiology]. Revue de l'Institut d'hygiene des mines, 1976, Volume: 31, Issue:1 Topics: Acetylcholine; Airway Obstruction; Albuterol; Bronchial Diseases; Bronchitis; Bronchodilator Agents;	1976
Relationship between spontaneous dyspnoea and lability of airway obstruction in asthma. Clinical science (London, England : 1979), 1992, Volume: 82, Issue:6 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchi; Carbachol; Dyspnea; Female;	1992
Albuterol. Neonatal network : NN, 1992, Volume: 11, Issue:7 Topics: Airway Obstruction; Albuterol; Bronchi; Drug Administration Schedule; Humans; Infant	1992
[Study of circadian rhythm of bronchial patency for timely correction and evaluation of the effectiveness of inhalation powder forms of salbutamol in children with bronchial asthma]. Pediatriia, 1992, Issue:4-6 Topics: Administration, Inhalation; Adolescent; Airway Obstruction; Albuterol; Asthma; Bronchi; Child; Circa	1992
Measures of reversibility in response to bronchodilators in chronic airflow obstruction: relation to airway calibre. Thorax, 1991, Volume: 46, Issue:1 Topics: Airway Obstruction; Albuterol; Bronchodilator Agents; Female; Forced Expiratory Volume; Humans; Ipra	1991
Bronchodilator and corticosteroid reversibility in ambulatory patients with airways obstruction. Danish medical bulletin, 1991, Volume: 38, Issue:6 Topics: Adolescent; Adrenal Cortex Hormones; Adult; Airway Obstruction; Albuterol; Bronchodilator Agents; Dr	1991
Inhaled formoterol inhibits histamine-induced airflow obstruction and airway microvascular leakage. European journal of pharmacology, 1991, Jan-25, Volume: 193, Issue:1 Topics: Administration, Inhalation; Airway Obstruction; Airway Resistance; Albuterol; Animals; Bronchodilato	1991
Reversal of A23187-induced airway constriction in the guinea pig. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Airway Obstruction; Airway Resistance; Albuterol; Animals; Calcimycin; Dose-Response Relationship, D	1989
The effect of cromolyn sodium and albuterol on early and late phase bronchoconstriction and airway leukocyte infiltration after allergen challenge of nonanesthetized guinea pigs. The American review of respiratory disease, 1988, Volume: 138, Issue:5 Topics: Airway Obstruction; Airway Resistance; Albuterol; Allergens; Animals; Asthma; Bronchi; Bronchoalveol	1988
Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics. Pediatric pulmonology, 1988, Volume: 4, Issue:4 Topics: Adolescent; Adult; Airway Obstruction; Albuterol; Child; Cystic Fibrosis; Drug Therapy, Combination;	1988
The perception of asthma. Australian paediatric journal, 1986, Volume: 22, Issue:1 Topics: Adolescent; Airway Obstruction; Albuterol; Asthma; Child; Female; Forced Expiratory Volume; Humans;	1986
Can thoracic gas volume be measured in infants with airways obstruction? The American review of respiratory disease, 1986, Volume: 133, Issue:2 Topics: Airway Obstruction; Airway Resistance; Albuterol; Bronchiolitis, Viral; Cystic Fibrosis; Functional	1986
Measurement of reversibility of airways obstruction: which parameters to use? Respiration; international review of thoracic diseases, 1985, Volume: 48, Issue:1 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Child; Female; Forced Expiratory Volume; Hum	1985
Bronchial asthma. The Practitioner, 1974, Volume: 212, Issue:1269 Topics: Adrenocorticotropic Hormone; Aerosols; Airway Obstruction; Albuterol; Aminophylline; Antigens; Asthm	1974
Changes in specific airways conductance and forced expiratory volume in one second after a bronchodilator in normal subjects and patients with airways obstruction. Thorax, 1974, Volume: 29, Issue:5 Topics: Administration, Oral; Adult; Aerosols; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bro	1974
[Treatment of bronchiolar obstruction]. Minerva medica, 1974, Dec-19, Volume: 65, Issue:91 Topics: Aerosols; Airway Obstruction; Albuterol; Asthma; Bronchial Diseases; Bronchial Spasm; Diagnosis, Dif	1974
A comparison of Berotec (Th1165a) and Salbutamol aerosols. The New Zealand medical journal, 1973, Sep-12, Volume: 78, Issue:498 Topics: Adult; Aerosols; Aged; Airway Obstruction; Albuterol; Blood Pressure; Bronchodilator Agents; Female;	1973
Closing volume, spirometry and nitrogen wash-out in provoked asthma treated with salbutamol. Scandinavian journal of respiratory diseases. Supplementum, 1974, Volume: 85 Topics: Adolescent; Adult; Airway Obstruction; Airway Resistance; Albuterol; Allergens; Asthma; Female; Huma	1974
Effect of salbutamol on the peripheral circulation in man. Chest, 1973, Volume: 64, Issue:4 Topics: Adolescent; Adult; Aerosols; Aged; Airway Obstruction; Albuterol; Blood Circulation; Blood Pressure;	1973
Management of severe viral bronchiolitis and severe acute asthma. Archives of disease in childhood, 1974, Volume: 49, Issue:2 Topics: Acute Disease; Airway Obstruction; Albuterol; Aminophylline; Anti-Bacterial Agents; Asthma; Bronchio	1974
An economical method of comparing inhaled bronchodilators in reversible diffuse airways obstruction. With special reference to a beta-2 stimulant--salmefamol. Thorax, 1974, Volume: 29, Issue:3 Topics: Adult; Aerosols; Airway Obstruction; Albuterol; Analysis of Variance; Bronchodilator Agents; Ethanol	1974

albuterol and Airway Obstruction