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albuterol and Aging

albuterol has been researched along with Aging in 32 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Both drugs are effective bronchodilators in young and old asthmatic subjects, but albuterol results in a greater magnitude of response in both age groups."5.07Effect of age on bronchodilator response. ( Abuan, TH; Driesner, NK; Emmick, G; Kradjan, WA; Schoene, RB, 1992)
"Chronic obstructive pulmonary disease is one of the most common chronic diseases throughout the world affecting prevalently older people."2.46Do we need different treatments for very elderly COPD patients? ( Bernabei, R; Corbo, GM; Pasciuto, G; Valente, S, 2010)
"Insulin resistant type 2 diabetes mellitus in the obese elderly has become a worldwide epidemic."1.38Chronic β2 adrenergic agonist, but not exercise, improves glucose handling in older type 2 diabetic mice. ( Elayan, H; Gharaibeh, M; Milic, M; Sun, P; Ziegler, MG, 2012)
"Both asthma and chronic obstructive pulmonary disease (COPD) are often underdiagnosed and undertreated among the elderly."1.33Treatment of acute bronchospasm in elderly patients. ( Berger, WE, 2005)
"Albuterol was inhaled via dosimeter (initially 7."1.29Impaired bronchodilator response to albuterol in healthy elderly men and women. ( Charan, NB; Connolly, MJ; Crowley, JJ; Nielson, CP; Vestal, RE, 1995)
" The aim of this study was to seek such a relationship in young asthmatic children using dose-response curves (DRC)."1.29The effect of age on bronchodilator responsiveness. ( Landau, LI; LeSouëf, PN; Turner, DJ, 1993)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.88)18.7374
1990's12 (37.50)18.2507
2000's8 (25.00)29.6817
2010's5 (15.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Şakul, A1
Arı, N1
Sotnikova, R1
Ozansoy, G1
Karasu, Ç1
Boudewijn, IM1
Postma, DS1
Telenga, ED1
Ten Hacken, NH1
Timens, W1
Oudkerk, M1
Ross, BD1
Galbán, CJ1
van den Berge, M1
Farrell, SR1
Howlett, SE1
Berger, WE1
Valente, S1
Pasciuto, G1
Bernabei, R1
Corbo, GM1
Thunhorst, RL1
Grobe, CL1
Beltz, TG1
Johnson, AK1
Elayan, H1
Milic, M1
Sun, P1
Gharaibeh, M1
Ziegler, MG1
Chhabra, SK1
Pandey, KK1
Parker, AL1
Darken, PF1
Fayon, M1
Dumas De La Roque, E1
Berger, P1
Begueret, H1
Ousova, O1
Molimard, M1
Marthan, R1
Wykretowicz, A1
Guzik, P1
Bartkowiak, G1
Krauze, T1
Kasinowski, R1
Dziarmaga, M1
Wesseling, KH1
Wysocki, H1
Goubareva, I1
Gkaliagkousi, E1
Shah, A1
Queen, L1
Ritter, J1
Ferro, A1
Reinhardt, D1
Zehmisch, T1
Becker, B1
Nagel-Hiemke, M1
Stessman, J2
Eliakim, R2
Cahan, C1
Ebstein, RP2
Yamazaki, N1
Hosoki, R1
Takayanagi, I1
Ullah, MI1
Newman, GB1
Saunders, KB1
Brink, C1
Duncan, PG1
Midzenski, M1
Douglas, JS1
Connolly, MJ1
Crowley, JJ1
Charan, NB1
Nielson, CP1
Vestal, RE1
Haidet, GC1
Wennberg, PW1
Rector, TS1
Charpentier, F1
Rosen, MR1
Carter, WJ1
Lynch, ME1
Turner, DJ1
Landau, LI1
LeSouëf, PN1
Dikshit, MB1
Vats, HK1
Gupta, CK1
Kamińsky, P1
Skopińska, RE1
Bany, J1
Wasik, M1
Sokolnicka, I1
Barcz, E1
Rogala, E1
Sommer, E1
Brajczewska, W1
Filewska, M1
Balan, B1
Skopiński, P1
Marianowksi, L1
Verbanck, S1
Schuermans, D1
Noppen, M1
Van Muylem, A1
Paiva, M1
Vincken, W1
Collins, JV1
Clark, TJ1
Brown, DJ1
Capuano, CA1
Leibowitz, SF1
Barr, GA1
Nisar, M1
Earis, JE1
Pearson, MG1
Calverley, PM1
Kradjan, WA1
Driesner, NK1
Abuan, TH1
Emmick, G1
Schoene, RB1
Lipworth, BJ1
Tregaskis, BF1
McDevitt, DG1
Menczel, J1

Reviews

1 review available for albuterol and Aging

ArticleYear
Do we need different treatments for very elderly COPD patients?
    Respiration; international review of thoracic diseases, 2010, Volume: 80, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Aging; Albuterol; Bronchodilator Agents; Glucocorticoids;

2010

Trials

4 trials available for albuterol and Aging

ArticleYear
Comparison of acute bronchodilator effects of inhaled ipratropium bromide and salbutamol in bronchial asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2002, Volume: 39, Issue:5

    Topics: Administration, Inhalation; Adult; Aging; Albuterol; Asthma; Bronchodilator Agents; Cross-Over Studi

2002
Helium/oxygen flow volume curves in normal Indian males > 50 year, and the effect of bronchodilator aerosols on airflow variables in this subject group.
    Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:4

    Topics: Aerosols; Aging; Albuterol; Bronchodilator Agents; Helium; Humans; India; Ipratropium; Male; Maximal

1995
Effect of age on bronchodilator response.
    Chest, 1992, Volume: 101, Issue:6

    Topics: Adolescent; Adult; Aging; Albuterol; Asthma; Blood Pressure; Bronchodilator Agents; Dose-Response Re

1992
Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:3

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Aging; Albuterol; Dose-Response Relation

1991

Other Studies

27 other studies available for albuterol and Aging

ArticleYear
A pyridoindole antioxidant SMe1EC2 regulates contractility, relaxation ability, cation channel activity, and protein-carbonyl modifications in the aorta of young and old rats with or without diabetes mellitus.
    GeroScience, 2018, Volume: 40, Issue:4

    Topics: Acetylcholine; Aging; Albuterol; Animals; Antioxidants; Aorta, Thoracic; Diabetes Mellitus, Experime

2018
Effects of ageing and smoking on pulmonary computed tomography scans using parametric response mapping.
    The European respiratory journal, 2015, Volume: 46, Issue:4

    Topics: Adult; Aging; Albuterol; Algorithms; Female; Forced Expiratory Volume; Humans; Inflammation; Linear

2015
The age-related decrease in catecholamine sensitivity is mediated by beta(1)-adrenergic receptors linked to a decrease in adenylate cyclase activity in ventricular myocytes from male Fischer 344 rats.
    Mechanisms of ageing and development, 2008, Volume: 129, Issue:12

    Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Aging; Albuterol;

2008
Treatment of acute bronchospasm in elderly patients.
    Postgraduate medicine, 2005, Volume: 118, Issue:6 Suppl Ac

    Topics: Acute Disease; Adrenal Cortex Hormones; Age Factors; Aged; Aged, 80 and over; Aging; Albuterol; Asth

2005
Effects of β-adrenergic receptor agonists on drinking and arterial blood pressure in young and old rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Albuterol; Animals; Blood Pressure; Dr

2011
Chronic β2 adrenergic agonist, but not exercise, improves glucose handling in older type 2 diabetic mice.
    Cellular and molecular neurobiology, 2012, Volume: 32, Issue:5

    Topics: Adrenergic Agonists; Aging; Albuterol; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diab

2012
Aging does not affect beta-agonist responsiveness after methacholine-induced bronchoconstriction.
    Journal of the American Geriatrics Society, 2004, Volume: 52, Issue:3

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Ag

2004
Evaluating assumptions for least squares analysis using the general linear model: a guide for the pharmaceutical industry statistician.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:3

    Topics: Aging; Albuterol; Androstadienes; Bronchodilator Agents; Data Interpretation, Statistical; Drug Indu

2004
Increased relaxation of immature airways to beta2-adrenoceptor agonists is related to attenuated expression of postjunctional smooth muscle muscarinic M2 receptors.
    Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 98, Issue:4

    Topics: Adrenergic beta-2 Receptor Antagonists; Aging; Albuterol; Animals; Animals, Newborn; Cells, Cultured

2005
Endothelial function and baroreflex sensitivity according to the oral glucose tolerance test in patients with coronary artery disease and normal fasting glucose levels.
    Clinical science (London, England : 1979), 2005, Volume: 109, Issue:4

    Topics: Adult; Aged; Aging; Albuterol; Angioplasty, Balloon, Coronary; Baroreflex; Blood Glucose; Coronary A

2005
Age decreases nitric oxide synthesis and responsiveness in human platelets and increases formation of monocyte-platelet aggregates.
    Cardiovascular research, 2007, Sep-01, Volume: 75, Issue:4

    Topics: Adult; Age Factors; Aging; Albuterol; Atherosclerosis; Blood Platelets; Blotting, Western; Calcium;

2007
Age-dependency of alpha- and beta-adrenoceptors on thrombocytes and lymphocytes of asthmatic and nonasthmatic children.
    European journal of pediatrics, 1984, Volume: 142, Issue:2

    Topics: Adolescent; Adult; Aging; Albuterol; Asthma; Blood Platelets; Child; Child, Preschool; Humans; Infan

1984
Deterioration of beta-receptor-adenylate cyclase function in elderly, hospitalized patients.
    Journal of gerontology, 1984, Volume: 39, Issue:6

    Topics: Adult; Aged; Aging; Albuterol; Blood Pressure; Cyclic AMP; Female; GTP-Binding Proteins; Humans; Inf

1984
Effect of clenbuterol, a new beta 2 selective adrenoceptor stimulant, on the release of histamine and SRS-A from passively sensitized guinea-pig chopped lungs.
    General pharmacology, 1984, Volume: 15, Issue:4

    Topics: Aging; Albuterol; Animals; Chromones; Clenbuterol; Ethanolamines; Guinea Pigs; Histamine Release; In

1984
Influence of age on response to ipratropium and salbutamol in asthma.
    Thorax, 1981, Volume: 36, Issue:7

    Topics: Adult; Aging; Albuterol; Asthma; Atropine Derivatives; Forced Expiratory Volume; Humans; Ipratropium

1981
Response and sensitivity of female guinea-pig respiratory tissues to agonists during ontogenesis.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:2

    Topics: Age Factors; Aging; Albuterol; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomet

1980
Impaired bronchodilator response to albuterol in healthy elderly men and women.
    Chest, 1995, Volume: 108, Issue:2

    Topics: Adult; Aged; Aging; Albuterol; Analysis of Variance; Bronchi; Bronchial Provocation Tests; Bronchoco

1995
Aging and vasoreactivity: in vivo responses in the beagle hindlimb.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Acetylcholine; Aging; Albuterol; Animals; Aorta; Blood Pressure; Dogs; Dose-Response Relationship, D

1995
Beta-adrenergic regulation of action potentials and automaticity in young and adult canine purkinje fibers.
    The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2

    Topics: Action Potentials; Adrenergic beta-Antagonists; Aging; Albuterol; Animals; Cardiac Pacing, Artificia

1994
Comparison of the effects of salbutamol and clenbuterol on skeletal muscle mass and carcass composition in senescent rats.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:9

    Topics: Adrenergic beta-Agonists; Aging; Albuterol; Animals; Body Composition; Body Weight; Clenbuterol; Cre

1994
The effect of age on bronchodilator responsiveness.
    Pediatric pulmonology, 1993, Volume: 15, Issue:2

    Topics: Aging; Albuterol; Asthma; Bronchi; Child; Child, Preschool; Dose-Response Relationship, Drug; Female

1993
The effect of salbutamol treatment on the cellular immunity of the offspring of pregnant mice: spleen cell activity.
    Drugs under experimental and clinical research, 1998, Volume: 24, Issue:2

    Topics: Adrenergic beta-Agonists; Aging; Albuterol; Animals; Animals, Newborn; Female; Immunity, Cellular; I

1998
Evidence of acinar airway involvement in asthma.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:5 Pt 1

    Topics: Adult; Aging; Albuterol; Asthma; Bronchodilator Agents; Female; Forced Expiratory Volume; Functional

1999
Airway function in healthy subjects and patients with left heart disease.
    Clinical science and molecular medicine, 1975, Volume: 49, Issue:3

    Topics: Adult; Aging; Airway Resistance; Albuterol; Female; Forced Expiratory Volume; Heart Diseases; Humans

1975
The pharmaco-ontogeny of the perifornical lateral hypothalamic beta 2-adrenergic and dopaminergic receptor systems mediating epinephrine- and dopamine-induced suppression of feeding in the rat.
    Brain research. Developmental brain research, 1992, Nov-20, Volume: 70, Issue:1

    Topics: Aging; Albuterol; Animals; Apomorphine; Dose-Response Relationship, Drug; Epinephrine; Feeding Behav

1992
Acute bronchodilator trials in chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1992, Volume: 146, Issue:3

    Topics: Aerosols; Aged; Aging; Albuterol; Bronchodilator Agents; Drug Evaluation; Female; Forced Expiratory

1992
The effect of age on beta-adrenergic function in man: a review.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:3

    Topics: Adenylyl Cyclases; Adult; Aged; Aging; Albuterol; Animals; Blood Pressure; Catecholamines; Cyclic AM

1985