albuterol has been researched along with Acidosis, Lactic in 35 studies
Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Initial severe acidosis consisted of acute respiratory acidosis from ventilation-perfusion mismatch and acute metabolic acidosis resulting from bronchospasm and hypoxia-related lactic acidosis, respectively." | 8.02 | Salbutamol-induced lactic acidosis in status asthmaticus survivor. ( Boonkaya, S; Phoophiboon, V; Singhagowinta, P; Sriprasart, T, 2021) |
| " Laboratory findings showed hypokalemia, hypophosphatemia, and lactic acidosis." | 7.78 | Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. ( Hantson, P; Manara, A; Thys, F; Vanpee, D, 2012) |
| " Initial severe acidosis consisted of acute respiratory acidosis from ventilation-perfusion mismatch and acute metabolic acidosis resulting from bronchospasm and hypoxia-related lactic acidosis, respectively." | 4.02 | Salbutamol-induced lactic acidosis in status asthmaticus survivor. ( Boonkaya, S; Phoophiboon, V; Singhagowinta, P; Sriprasart, T, 2021) |
| " Laboratory findings showed hypokalemia, hypophosphatemia, and lactic acidosis." | 3.78 | Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. ( Hantson, P; Manara, A; Thys, F; Vanpee, D, 2012) |
| "Hypokalemia and lactic acidosis developed following correction of respiratory acidosis in a 5-year-old child who presented with respiratory failure secondary to severe asthma and treated with theophylline, inhaled albuterol, and parenteral methylprednisolone." | 3.67 | Therapy of acute bronchospasm. Complicated by lactic acidosis and hypokalemia. ( Assadi, FK, 1989) |
| "Lactic acidosis is a common complication of status asthmaticus in adults." | 1.62 | Prevalence and risk factors of lactic acidosis in children with acute moderate and severe asthma, a prospective observational study. ( Di Paolo, ER; Gehri, M; Pauchard, JY; Rochat Guignard, I; Ruman-Colombier, M, 2021) |
| "Although lactic acidosis is a rare side effect to β ² agonist treatment, it is important to recog-nize it when present." | 1.43 | [Lactic acidosis in a 24-year-old woman with status asthmaticus]. ( Albertsen, S; Bergmann, TK; Madsen, PH; Ramazan-Yousif, L; Steen, NP, 2016) |
| "Lactic acidosis is commonly used as a clinical marker for sepsis and shock, but in the absence of tissue hypoperfusion and severe hypoxia, alternative aetiologies for elevated levels should be sought to avoid unnecessary and potentially harmful medical interventions." | 1.39 | Inhaled β-agonist therapy and respiratory muscle fatigue as under-recognised causes of lactic acidosis. ( Carino, G; Lau, E; Mazer, J, 2013) |
| "Although lactic acidosis is a rare complication to inhalation of beta-agonists, it is important for the clinicians to recognize this." | 1.39 | [Lactic acidosis in a patient with exercabation of asthma receiving inhalation therapy]. ( Ekelund, K; Følsgaard, S, 2013) |
| " Lactic acidosis improved within 24 h after discontinuation or decrease in the dosage of beta2-agonists." | 1.34 | Lactic acidosis in children with acute exacerbation of severe asthma. ( Koul, PB; Minarik, M; Totapally, BR, 2007) |
| "Shoshin beriberi is an acute, cardiac form of beriberi, which can rapidly result in death due to cardiogenic shock and lactate acidosis." | 1.32 | [Shoshin beriberi provoked by the inhalation of salbutamol]. ( Baur, HJ; Geelhoed-Duijvestijn, PH; Groeneveld, JH; Veldkamp, RF, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.86) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 11 (31.43) | 29.6817 |
| 2010's | 14 (40.00) | 24.3611 |
| 2020's | 4 (11.43) | 2.80 |
| Authors | Studies |
|---|---|
| Colombo, M | 1 |
| Plebani, A | 1 |
| Bosco, A | 1 |
| Agosti, M | 1 |
| Pearmain, L | 1 |
| Gupta, R | 1 |
| Bright-Thomas, RJ | 1 |
| Ruman-Colombier, M | 1 |
| Rochat Guignard, I | 1 |
| Di Paolo, ER | 1 |
| Gehri, M | 1 |
| Pauchard, JY | 1 |
| Phoophiboon, V | 1 |
| Singhagowinta, P | 1 |
| Boonkaya, S | 1 |
| Sriprasart, T | 1 |
| Sharif, Z | 1 |
| Al-Alawi, M | 1 |
| Lau, E | 1 |
| Mazer, J | 1 |
| Carino, G | 1 |
| Moustafa, F | 1 |
| Garrouste, C | 1 |
| Bertrand, PM | 1 |
| Kauffmann, S | 1 |
| Schmidt, J | 1 |
| Senthilkumaran, S | 1 |
| Shah, S | 1 |
| Menezes, RG | 1 |
| Thirumalaikolundusubramanian, P | 1 |
| Isaac, BT | 1 |
| McLellan, T | 1 |
| Samuel, J | 1 |
| Yung, B | 1 |
| Ramazan-Yousif, L | 1 |
| Albertsen, S | 1 |
| Bergmann, TK | 1 |
| Madsen, PH | 1 |
| Steen, NP | 1 |
| Gómez Bustos, MD | 1 |
| García Ron, A | 1 |
| Ibarra de la Rosa, I | 1 |
| Pérez Navero, JL | 1 |
| González Jiménez, D | 1 |
| Concha Torre, A | 1 |
| Menéndez Cuervo, S | 1 |
| García Hernández, I | 1 |
| Kovacevic, A | 1 |
| Schwahn, B | 1 |
| Schuster, A | 1 |
| Mishra, RK | 1 |
| Radhi, S | 1 |
| Nugent, KM | 1 |
| Sturney, S | 1 |
| Suntharalingam, J | 1 |
| Dodda, VR | 1 |
| Spiro, P | 1 |
| Saxena, R | 1 |
| Marais, G | 1 |
| Manara, A | 1 |
| Hantson, P | 1 |
| Vanpee, D | 1 |
| Thys, F | 1 |
| Lauritsen, L | 1 |
| Sahl, C | 1 |
| Thorsen, S | 1 |
| Ekelund, K | 1 |
| Følsgaard, S | 1 |
| Stratakos, G | 1 |
| Kalomenidis, J | 1 |
| Routsi, C | 1 |
| Papiris, S | 1 |
| Roussos, C | 1 |
| Liem, EB | 1 |
| Mnookin, SC | 1 |
| Mahla, ME | 1 |
| Groeneveld, JH | 1 |
| Geelhoed-Duijvestijn, PH | 1 |
| Veldkamp, RF | 1 |
| Baur, HJ | 1 |
| Girgis, M | 1 |
| Milner, Q | 1 |
| Du-Thanh, A | 1 |
| Groleron, S | 1 |
| Le Quellec, A | 1 |
| Sobolev, I | 1 |
| Koul, PB | 1 |
| Minarik, M | 1 |
| Totapally, BR | 1 |
| Chaulier, K | 1 |
| Chalumeau, S | 1 |
| Ber, CE | 1 |
| Bret, M | 1 |
| Rimmelé, T | 1 |
| Creagh-Brown, BC | 1 |
| Ball, J | 1 |
| Gmehlin, U | 1 |
| Stenz, R | 1 |
| Stoz, F | 1 |
| Taboulet, P | 1 |
| Clemessy, JL | 1 |
| Freminet, A | 1 |
| Baud, FJ | 1 |
| Maury, E | 1 |
| Ioos, V | 1 |
| Lepecq, B | 1 |
| Guidet, B | 1 |
| Offenstadt, G | 1 |
| Haffner, CA | 1 |
| Kendall, MJ | 1 |
| Guichenez, P | 1 |
| Girard-Madoux, MH | 1 |
| Coppere, B | 1 |
| Sanson, C | 1 |
| Ninet, J | 1 |
| Assadi, FK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Various Effects of Gaseous Albuterol on Serum Lactate[NCT02073747] | 28 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
We powered our study to detect a difference of 0.5 mmol/L between pre and post-treatment lactate levels, but hypothesize that the difference will be greater than 1.0 mmol/L. (NCT02073747)
Timeframe: Change in serum lactate from baseline to 1 hour
| Intervention | mmol/L (Mean) |
|---|---|
| Normal Saline Control Group | -0.15 |
| Albuterol Trial Group | 0.77 |
2 reviews available for albuterol and Acidosis, Lactic
| Article | Year |
|---|---|
A paradoxical effect of bronchodilators.
Topics: Acidosis, Lactic; Acute Disease; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; | 1997 |
Metabolic effects of beta 2-agonists.
Topics: Acidosis, Lactic; Acute Disease; Adrenergic beta-Agonists; Albuterol; Asthma; Female; Glucose; Human | 1992 |
33 other studies available for albuterol and Acidosis, Lactic
| Article | Year |
|---|---|
Severe lactic acidosis and persistent diastolic hypotension following standard dose of intermittent nebulized salbutamol in a child: a case report.
Topics: Acidosis, Lactic; Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Child; Famil | 2022 |
Lessons of the month 1: Salbutamol induced lactic acidosis: clinically recognised but often forgotten.
Topics: Acidosis, Lactic; Administration, Inhalation; Aged, 80 and over; Albuterol; Asthma; Female; Humans | 2020 |
Prevalence and risk factors of lactic acidosis in children with acute moderate and severe asthma, a prospective observational study.
Topics: Acidosis, Lactic; Adolescent; Albuterol; Asthma; Child; Child, Preschool; Humans; Prevalence; Risk F | 2021 |
Salbutamol-induced lactic acidosis in status asthmaticus survivor.
Topics: Acidosis; Acidosis, Lactic; Acidosis, Respiratory; Adrenergic beta-2 Receptor Agonists; Adult; Albut | 2021 |
Beware of beta! A case of salbutamol-induced lactic acidosis in severe asthma.
Topics: Acidosis, Lactic; Acute Disease; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Al | 2018 |
Inhaled β-agonist therapy and respiratory muscle fatigue as under-recognised causes of lactic acidosis.
Topics: Acidosis, Lactic; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Albuterol; Diagno | 2013 |
[Lactic acidosis after inhaled beta-2 agonists: about 2 cases].
Topics: Acidosis, Lactic; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Albuterol; Asthma | 2014 |
Salmeterol and lactic acidosis: clinical and educational aspects.
Topics: Acidosis, Lactic; Albuterol; Androstadienes; Asthma; Drug Overdose; Female; Humans; Intention; Lacti | 2014 |
Conundrum in an asthma exacerbation.
Topics: Acidosis, Lactic; Adrenal Cortex Hormones; Aged; Albuterol; Asthma; Humans; Male; Prednisolone; Trea | 2016 |
[Lactic acidosis in a 24-year-old woman with status asthmaticus].
Topics: Acidosis, Lactic; Adrenergic beta-2 Receptor Agonists; Albuterol; Asthma; Female; Humans; Lactates; | 2016 |
[Lactic acidosis induced by inhaling high doses of salbutamol].
Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Albuterol; Femal | 2008 |
[Lactic acidosis secondary to inhaled salbutamol in children with acute severe asthma].
Topics: Acidosis, Lactic; Acute Disease; Administration, Inhalation; Adolescent; Albuterol; Asthma; Bronchod | 2009 |
Hyperlactic acidosis as metabolic side-effect of albuterol and theophylline in acute severe asthma.
Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Albuterol; Anti-Asthmatic Agents; Anti-Inf | 2010 |
A 20-year-old woman with severe asthma refractory to Primatene Mist.
Topics: Acidosis, Lactic; Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Cholinergic | 2010 |
Treating acute asthma--salbutamol may not always be the right answer.
Topics: Acidosis, Lactic; Acute Disease; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Al | 2012 |
Can albuterol be blamed for lactic acidosis?
Topics: Acidosis, Lactic; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Bronchodilator Agents; Dise | 2012 |
Salbutamol: beware of the paradox!
Topics: Acidosis, Lactic; Albuterol; Blood Gas Analysis; Bronchodilator Agents; Child; Emergency Service, Ho | 2010 |
Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone.
Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Albut | 2012 |
[Nebulized salbutamol as a possible cause of lactate acidosis in a patient with acute asthma].
Topics: Acidosis, Lactic; Acute Disease; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Al | 2013 |
[Lactic acidosis in a patient with exercabation of asthma receiving inhalation therapy].
Topics: Acidosis, Lactic; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; | 2013 |
Transient lactic acidosis as a side effect of inhaled salbutamol.
Topics: Acidosis, Lactic; Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Humans | 2002 |
Albuterol-induced lactic acidosis.
Topics: Acidosis, Lactic; Administration, Inhalation; Adult; Albuterol; Anesthesia, General; Anti-Asthmatic | 2003 |
[Shoshin beriberi provoked by the inhalation of salbutamol].
Topics: Acidosis, Lactic; Acute Disease; Administration, Inhalation; Albuterol; Beriberi; Bronchodilator Age | 2003 |
A rare side-effect of intravenous salbutamol.
Topics: Acidosis, Lactic; Albuterol; Asthma; Bronchodilator Agents; Humans; Infusions, Intravenous; Male; Mi | 2004 |
[Lactic acidosis occurring after inhaled beta2 agonists during an asthma attack].
Topics: Acidosis, Lactic; Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Asthma; Female; H | 2004 |
A response to 'A rare side-effect of intravenous salbutamol', Girgis M and Milner Q, Anaesthesia 2004; 59: 196-7.
Topics: Acidosis, Lactic; Adult; Albuterol; Asthma; Bronchodilator Agents; Female; Humans | 2004 |
Lactic acidosis in children with acute exacerbation of severe asthma.
Topics: Acidosis, Lactic; Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; Child; Humans; Male; Retr | 2007 |
[Metabolic acidosis in a context of acute severe asthma].
Topics: Acidosis, Lactic; Acute Disease; Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Middle Ag | 2007 |
An under-recognized complication of treatment of acute severe asthma.
Topics: Acidosis, Lactic; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Humans; Male; Respiration, Artifi | 2008 |
[Metabolic acidosis in the 32nd week of pregnancy--uncontrolled diabetes in pregnancy, dehydration or sequela of tocolysis?].
Topics: Acidosis, Lactic; Adult; Albuterol; Blood Glucose; Cesarean Section; Dehydration; Diabetes Mellitus, | 1994 |
A case of life-threatening lactic acidosis after smoke inhalation - interference between beta-adrenergic agents and ethanol?
Topics: Acidosis, Lactic; Adrenergic beta-Agonists; Albuterol; Alcoholic Intoxication; Alcoholism; Bronchial | 1995 |
[Metabolic acidosis related to salbutamol use during treatment of acute bronchospasm].
Topics: Acidosis, Lactic; Aged; Albuterol; Blood Gas Analysis; Bronchial Spasm; Humans; Male; Middle Aged | 1991 |
Therapy of acute bronchospasm. Complicated by lactic acidosis and hypokalemia.
Topics: Acidosis, Lactic; Acute Disease; Albuterol; Bronchial Spasm; Child, Preschool; Drug Therapy, Combina | 1989 |