Page last updated: 2024-10-22

albendazole and Pregnancy

albendazole has been researched along with Pregnancy in 88 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"A randomized open-label trial, including 834 pregnant women, examined efficacy and recorded adverse events of ivermectin (ivc) and albendazole (alb) alone and combined (comb) on soil-transmitted helminth infections (STHs) in the second trimester of pregnancy."9.13Efficacy of ivermectin and albendazole alone and in combination for treatment of soil-transmitted helminths in pregnancy and adverse events: a randomized open label controlled intervention trial in Masindi district, western Uganda. ( Kabatereine, N; Magnussen, P; Ndyomugyenyi, R; Olsen, A, 2008)
"In Entebbe, Uganda, we conducted a randomised, double-blind, placebo-controlled trial of a single dose of 400 mg of albendazole in the second trimester of pregnancy."9.11A randomised controlled trial of the effects of albendazole in pregnancy on maternal responses to mycobacterial antigens and infant responses to Bacille Calmette-Guérin (BCG) immunisation [ISRCTN32849447]. ( Belisle, JT; Elliott, AM; Mawa, PA; Muwanga, M; Nampijja, M; Namujju, PB; Nkurunziza, PM; Quigley, MA; Whitworth, JA, 2005)
" Due to heterogeneity in terms of study design, sample size, deworming drug, dosage and outcomes measured, data from these studies could not be pooled."6.61Systematic review of exposure to albendazole or mebendazole during pregnancy and effects on maternal and child outcomes, with particular reference to exposure in the first trimester. ( Gyorkos, TW; St-Denis, K, 2019)
" During pregnancy, women were randomized, simultaneously, to albendazole vs placebo and to praziquantel vs placebo."5.24Effects of treating helminths during pregnancy and early childhood on risk of allergy-related outcomes: Follow-up of a randomized controlled trial. ( Akello, F; Akurut, H; Elliott, AM; Kabagenyi, J; Kizza, M; Lule, SA; Mpairwe, H; Muhangi, L; Muwanga, M; Namara, B; Nash, S; Nkurunungi, G; Tumusiime, J; Webb, EL, 2017)
"Routine use of albendazole in pregnancy may not always be beneficial, even in tropical developing countries."5.16Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial. ( Akello, F; Akurut, H; Alcock, KJ; Apule, B; Elliott, AM; Kihembo, M; Kizindo, R; Kizito, D; Kizza, M; Lule, SA; Mawa, PA; Mpairwe, H; Muhangi, L; Muwanga, M; Nampijja, M; Naniima, P; Ndibazza, J; Oduru, G; Rutebarika, D; Tweyongere, R; Webb, EL, 2012)
"To investigate the effect of helminth infections and their treatment during pregnancy on HIV load, we conducted a 2 × 2 factorial randomized controlled trial of albendazole versus placebo and praziquantel versus placebo in pregnant women in Entebbe, Uganda."5.16The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda. ( Elliott, AM; Kaleebu, P; Kizito, D; Kyosiimire-Lugemwa, J; Lule, S; Muhangi, L; Muwanga, M; Nkurunziza, P; Webb, EL, 2012)
"A randomised, double-blind, placebo-controlled trial on treatment in pregnancy with albendazole versus placebo and praziquantel versus placebo was conducted in Uganda, with a 2 × 2 factorial design; 2507 women were enrolled; infants' allergy events were recorded prospectively."5.15Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results. ( Akishule, D; Dunne, DW; Elliott, AM; Fitzsimmons, C; Jones, FM; Mpairwe, H; Muhangi, L; Muwanga, M; Nampijja, M; Ndibazza, J; Ngom-wegi, S; Rodrigues, LC; Tumusime, J; Webb, EL, 2011)
"A randomized open-label trial, including 834 pregnant women, examined efficacy and recorded adverse events of ivermectin (ivc) and albendazole (alb) alone and combined (comb) on soil-transmitted helminth infections (STHs) in the second trimester of pregnancy."5.13Efficacy of ivermectin and albendazole alone and in combination for treatment of soil-transmitted helminths in pregnancy and adverse events: a randomized open label controlled intervention trial in Masindi district, western Uganda. ( Kabatereine, N; Magnussen, P; Ndyomugyenyi, R; Olsen, A, 2008)
"In Entebbe, Uganda, we conducted a randomised, double-blind, placebo-controlled trial of a single dose of 400 mg of albendazole in the second trimester of pregnancy."5.11A randomised controlled trial of the effects of albendazole in pregnancy on maternal responses to mycobacterial antigens and infant responses to Bacille Calmette-Guérin (BCG) immunisation [ISRCTN32849447]. ( Belisle, JT; Elliott, AM; Mawa, PA; Muwanga, M; Nampijja, M; Namujju, PB; Nkurunziza, PM; Quigley, MA; Whitworth, JA, 2005)
"A longitudinal study was conducted in Sierra Leone to measure the impact of a single dose anthelminthic (400 mg albendazole) and daily iron-folate supplements (36 g iron and 5 mg folate) on haemoglobin (HG) concentration during pregnancy."5.09Anthelminthic treatment and haemoglobin concentrations during pregnancy. ( Hodges, M; Torlesse, H, 2000)
" Our analysis supports that albendazole in pregnancy has high cure rates for soil-transmitted helminths and is safe for the mother."5.05Treatment of soil-transmitted helminth infections in pregnancy: a systematic review and meta-analysis of maternal outcomes. ( Bhasker, S; Boggild, AK; Chris, RB; Khatib, A; Kopalakrishnan, S; Lau, R; Lecce, C; Mishra, S; Phuong, MS; Raheel, H; Yegorov, S, 2020)
"The 'Informal Consultation on the Use of Praziquantel during Pregnancy/Lactation, and Albendazole/Mebendazole in Children under 24 Months' was held 8-9 April 2002, in Geneva, Switzerland."4.81New policies for using anthelmintics in high risk groups. ( Allen, HE; Crompton, DW; de Silva, N; LoVerde, PT; Olds, GR, 2002)
" The lambs were treated with albendazole (SmithKline Beecham), fenbendazole (Hoechst Roussel) or a vitamin supplement and their weight gains were followed over the next 7 months."3.68Effects of an anthelmintic treatment programme on sheep productivity in the Middle Atlas, Morocco. ( Khallaayoune, K; Stromberg, BE, 1992)
"Albendazole (400mg) was administered to assess efficacy and hookworm re-infection rate."3.11Hookworm re-infection rate and efficacy of single-dose albendazole among pregnant women in Debre Elias District, Northwest Ethiopia: A single-arm trial. ( Abebaw, A; Aschale, Y; Atnaf, A; Kassie, B; Mengist, A; Yihunie, W, 2022)
"Eczema was doctor-diagnosed from birth to age five years."2.79Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda. ( Akurut, H; Apule, B; Dunne, DW; Elliott, AM; Fitzsimmons, CM; Jones, FM; Kakande, M; Kizito, D; Lule, S; Mpairwe, H; Muhangi, L; Muwanga, M; Nampijja, M; Ndibazza, J; Rodrigues, LC; Webb, EL, 2014)
"Albendazole (ABZ) has been used for control of ovine fasciolosis in Sweden for several decades."2.77The field evaluation of albendazole and triclabendazole efficacy against Fasciola hepatica by coproantigen ELISA in naturally infected sheep. ( Averpil, HB; Höglund, J; Novobilský, A, 2012)
"Deworming during pregnancy has therefore been strongly advocated, but its benefits have not been rigorously evaluated."2.75Effects of deworming during pregnancy on maternal and perinatal outcomes in Entebbe, Uganda: a randomized controlled trial. ( Akishule, D; Ameke, C; Duong, T; Elliott, AM; Kiggundu, M; Kizindo, R; Kleinschmidt, I; Muhangi, L; Muwanga, M; Ndibazza, J; Oweka, J, 2010)
"Helminthiasis is an infestation of the human body with parasitic worms."2.72Effect of mass deworming with antihelminthics for soil-transmitted helminths during pregnancy. ( Bhutta, ZA; Das, JK; Salam, RA, 2021)
" Due to heterogeneity in terms of study design, sample size, deworming drug, dosage and outcomes measured, data from these studies could not be pooled."2.61Systematic review of exposure to albendazole or mebendazole during pregnancy and effects on maternal and child outcomes, with particular reference to exposure in the first trimester. ( Gyorkos, TW; St-Denis, K, 2019)
"Helminthiasis is infestation of the human body with parasitic worms and it is estimated to affect 44 million pregnancies, globally, each year."2.52Effect of administration of antihelminthics for soil-transmitted helminths during pregnancy. ( Bhutta, ZA; Haider, BA; Humayun, Q; Salam, RA, 2015)
"Helminthiasis is infestation of the human body with parasitic worms and it is estimated to affect 44 million pregnancies, globally, each year."2.45Effect of administration of antihelminthics for soil transmitted helminths during pregnancy. ( Bhutta, ZA; Haider, BA; Humayun, Q, 2009)
"Albendazole (ABZ) is an effective therapeutic drug for adult T."1.91Treatment of pregnant mice with ABZ had no effect on the immune response of their offspring infected with Trichinella spiralis. ( Cao, X; Fan, S; Huang, H; Jiang, Y; Lu, H; Ma, R; Niu, T; Quan, Y; Shi, C; Wang, C; Wang, J; Wang, N; Wang, Y; Yang, G; Yang, W; Zeng, Y; Zhu, Z; Zou, B, 2023)
"Albendazole has been found more efficient in reducing EPG of helminths in both parity animals as compared to levamisole-treated animals while the cost-benefit ratio of levamisole was greater than albendazole."1.48Anthelmintic Drugs: Their Efficacy and Cost-Effectiveness in Different Parity Cattle. ( Akbar, H; Ali, MS; Ashraf, K; Ijaz, M; Rashid, I; Rashid, M; Saeed, K, 2018)
"Albendazole was not used."1.39Hepatic hydatid disease requiring urgent treatment during pregnancy. ( Alper, A; Bilge, O; Emre, A; Erçetin, C; Güven, K; Iyibozkurt, C; Özden, I; Serin, K; Tekant, Y, 2013)
"A cardiac hydatid cyst in pregnancy is a very rare condition."1.37A pericardial hydatid cyst and pregnancy. ( Altay, H; Erol, T; Tarim, E, 2011)
"Albendazole has teratogenic effects attributed to its active metabolite albendazole sulphoxide."1.37Evaluation of potential embryo toxicity of albendazole sulphoxide in CF1 mice. ( Catalano, R; Dercole, J; Teruel, M, 2011)
"We report a case of right ventricle hydatid cyst detected after syncopal attack in a pregnant woman by using echocardiography."1.35Hydatid cyst of the right ventricle in early pregnancy. ( Abbasi, A; Marzban, M; Sahebjam, M; Shirani, S; Soleimani, A, 2008)
"Hydatid cyst is still an important disease."1.33Primary hydatid cyst of the brain during pregnancy. ( Etlik, O; Kiymaz, N; Yazici, T; Yilmaz, N, 2006)
"Hydatid disease is primarily a disease of sheep and cattle."1.32Hepatic and splenic hydatid cyst during pregnancy: a case report. ( Can, D; Oztekin, O; Sanci, M; Tinar, S, 2003)
"Cystic hydatid disease is a zoonotic infection of humans caused by infection with the larval stage of Echinococcus granulosus."1.32Review of surgical management of cystic hydatid disease in a resource limited setting: Turkana, Kenya. ( Cooney, RM; Flanagan, KP; Zehyle, E, 2004)
"Neurocysticercosis is an infection of the central nervous system with the pork tapeworm's cysticercus."1.30Neurocysticercosis in pregnancy: a case initially diagnosed as eclampsia. ( Iannucci, TA; Suarez, VR, 1999)
" There were no adverse effects of albendazole at a dosage of 10 or 15 mg/kg on developing embryos or fetuses when administered to presumed pregnant cows at various times in early gestation."1.29Safety of albendazole in developing bovine fetuses. ( Carakostas, MC; Colaianne, JJ; Freeman, JF; Page, SW; Theodorides, VJ, 1993)
" Where lambs were weaned by removing ewes from the lambing paddock, administration of the CRC at weaning to lambs whose dams had also been treated with the CRC did not result in improved production when compared with lambs from ewes dosed with CRCs and treated after weaning according to the Wormkill program."1.29Effects of a controlled-release albendazole capsule on parasitism and production from grazing Merino ewes and lambs. ( Barger, IA; Rodden, BR; Steel, JW, 1993)
"The possible correlations between embryotoxicity, plasma kinetics of toxic metabolites and covalent binding of metabolites to foetal tissues were studied using two drugs, albendazole and oxfendazole."1.27A correlation of toxicity of albendazole and oxfendazole with their free metabolites and bound residues. ( Benoit, E; Delatour, P; Garnier, F; Longin, C, 1984)

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-19904 (4.55)18.7374
1990's15 (17.05)18.2507
2000's29 (32.95)29.6817
2010's30 (34.09)24.3611
2020's10 (11.36)2.80

Authors

AuthorsStudies
Hendrixson, DT1
Smith, K1
Lasowski, P1
Callaghan-Gillespie, M1
Weber, J1
Papathakis, P1
Iversen, PO1
Koroma, AS1
Manary, MJ1
Aschale, Y1
Abebaw, A1
Atnaf, A1
Mengist, A1
Kassie, B1
Yihunie, W1
Cunningham, FG1
Twickler, DM1
Fan, S1
Wang, Y3
Ma, R1
Niu, T1
Zou, B1
Quan, Y1
Lu, H2
Zhu, Z1
Shi, C1
Yang, W1
Jiang, Y2
Cao, X2
Wang, J5
Huang, H2
Zeng, Y1
Wang, N1
Yang, G1
Wang, C4
Lau, R1
Chris, RB1
Phuong, MS1
Khatib, A1
Kopalakrishnan, S1
Bhasker, S1
Raheel, H1
Lecce, C1
Yegorov, S1
Mishra, S1
Boggild, AK1
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J2
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Ma, Q1
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y4
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Li, C1
Chen, W2
Hu, X1
Zhang, F1
Wei, H1
Wang, Z1
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q2
Lyu, Y1
Huang, J1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
Ryan, CM1
Bellingham, G1
Singh, M2
Waseem, R1
Eckert, DJ1
Chung, F1
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Liu, SF1
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Turkyilmaz, IB1
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Yanardag, R1
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Alexander, R1
Mondal, A1
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Chakraborty, NK1
Dasgupta, K1
Sharma, AMR1
Hawaldar, R1
Pandey, M1
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Majumdar, K1
Pal, SK1
Adarsh, KV1
Ray, SK1
Karmakar, D1
Ma, Y2
Gao, W1
Ma, S1
Lin, W1
Zhou, T1
Wu, T1
Wu, Q1
Ye, C1
He, X1
Jiang, F1
Yuan, D1
Chen, Q1
Hong, M1
Chen, K1
Hussain, M1
Razi, SS1
Yildiz, EA1
Zhao, J1
Yaglioglu, HG1
Donato, MD1
Jiang, J1
Jamil, MI1
Zhan, X1
Chen, F1
Cheng, D1
Wu, CT1
Utsunomiya, T1
Ichii, T1
Fujinami, S1
Nakajima, K1
Sanchez, DM1
Raucci, U1
Ferreras, KN1
Martínez, TJ1
Mordi, NA1
Mordi, IR1
Singh, JS1
McCrimmon, RJ1
Struthers, AD1
Lang, CC1
Wang, XW1
Yuan, LJ1
Yang, Y1
Chen, WF1
Luo, R1
Yang, K1
Amarasiri, SS1
Attanayake, AP1
Arawwawala, LDAM1
Jayatilaka, KAPW1
Mudduwa, LKB1
Ogunsuyi, O2
Akanni, O1
Alabi, O1
Alimba, C1
Adaramoye, O1
Cambier, S1
Eswara, S1
Gutleb, AC1
Bakare, A1
Gu, Z1
Cong, J1
Pellegrini, M1
Palmieri, S1
Ricci, A1
Serio, A1
Paparella, A1
Lo Sterzo, C1
Jadeja, SD1
Vaishnav, J1
Mansuri, MS1
Shah, C1
Mayatra, JM1
Shah, A1
Begum, R1
Song, H2
Lian, Y1
Wan, T1
Schultz-Lebahn, A1
Skipper, MT1
Hvas, AM1
Larsen, OH1
Hijazi, Z1
Granger, CB1
Hohnloser, SH1
Westerbergh, J1
Lindbäck, J1
Alexander, JH1
Keltai, M1
Parkhomenko, A1
López-Sendón, JL1
Lopes, RD1
Siegbahn, A1
Wallentin, L1
El-Tarabany, MS1
Saleh, AA1
El-Araby, IE1
El-Magd, MA1
van Ginkel, MPH1
Schijven, MP1
van Grevenstein, WMU1
Schreuder, HWR1
Pereira, EDM1
da Silva, J1
Carvalho, PDS1
Grivicich, I1
Picada, JN1
Salgado Júnior, IB1
Vasques, GJ1
Pereira, MADS1
Reginatto, FH1
Ferraz, ABF1
Vasilenko, EA1
Gorshkova, EN1
Astrakhantseva, IV1
Drutskaya, MS1
Tillib, SV1
Nedospasov, SA1
Mokhonov, VV1
Nam, YW1
Cui, M1
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Rahighi, S1
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Kahanovitch, U1
Gonçalves, CM1
Hablitz, JJ1
Staruschenko, A1
Mulkey, DK1
Olsen, ML1
Gu, L1
Mukhtar, A1
Wu, K1
Zhang, YY1
Zhu, Y1
Lu, DZ1
Dong, W1
Bi, WJ1
Feng, XJ1
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Dinh, TK1
Lee, YA1
Wang, FN1
Sung, YC1
Yu, PL1
Chiu, SC1
Shih, YC1
Wu, CY1
Huang, YD1
Lu, TT1
Wan, D1
Sakizadeh, J1
Cline, JP1
Snyder, MA1
Kiely, CJ1
McIntosh, S1
Jiang, X1
Cao, JW1
Zhao, CK1
Yang, R1
Zhang, QY1
Chen, KJ2
Liu, H1
He, Z1
Chen, B1
Wu, J1
Du, X1
Moore, J1
Blank, BR1
Eksterowicz, J1
Sutimantanapi, D1
Yuen, N1
Metzger, T1
Chan, B1
Huang, T1
Chen, X1
Duong, F1
Kong, W1
Chang, JH1
Sun, J1
Zavorotinskaya, T1
Ye, Q1
Junttila, MR1
Ndubaku, C1
Friedman, LS1
Fantin, VR1
Sun, D1
Fei, P1
Xie, Q1
Feng, H1
Chang, Y1
Kang, H1
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Chen, J1
Shao, Z1
Yuan, C1
Wu, Y1
Allan, R1
Canham, K1
Wallace, R1
Singh, D1
Ward, J1
Cooper, A1
Newcomb, C1
Nammour, S1
El Mobadder, M1
Maalouf, E1
Namour, M1
Namour, A1
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Machado, FA1
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Dearman, K1
Kotwal, A1
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Medvedovsky, AT1
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Perlman, GY1
Danenberg, HD1
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Yang, D1
Sarapulova, A1
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Ehrenberg, H1
Kim, CC1
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Nam, KT1
Sun, JY1
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Duan, Z1
Kershaw, SV1
Rogach, AL1
Gao, Z1
Wang, T1
Li, Q1
Cao, T1
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Seeger, ZL1
Izgorodina, EI1
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Beldi-Ferchiou, A1
Bendib, I1
Surenaud, M1
Fourati, S1
Frapard, T1
Rivoal, S1
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Carteaux, G1
Delfau-Larue, MH1
Mekontso-Dessap, A1
Audureau, E1
de Prost, N1
Gao, SS1
Duangthip, D1
Lo, ECM1
Chu, CH1
Roberts, W1
Rosenheck, RA1
Miyake, T1
Kimoto, E1
Luo, L1
Mathialagan, S1
Horlbogen, LM1
Ramanathan, R1
Wood, LS1
Johnson, JG1
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Vourvahis, M1
Rodrigues, AD1
Muto, C1
Furihata, K1
Sugiyama, Y1
Kusuhara, H1
Gong, Q1
Song, W1
Sun, B1
Cao, P1
Gu, S1
Sun, X1
Zhou, G1
Toma, C1
Khandhar, S1
Zalewski, AM1
D'Auria, SJ1
Tu, TM1
Jaber, WA1
Cho, J2
Suwandaratne, NS1
Razek, S1
Choi, YH1
Piper, LFJ1
Watson, DF1
Banerjee, S1
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Lindsay, AP1
Bates, FS1
Lodge, TP1
Hao, Y1
Chapovetsky, A1
Liu, JJ1
Welborn, M1
Luna, JM1
Do, T1
Haiges, R1
Miller Iii, TF1
Marinescu, SC1
Lopez, SA1
Compter, I1
Eekers, DBP1
Hoeben, A1
Rouschop, KMA1
Reymen, B1
Ackermans, L1
Beckervordersantforth, J1
Bauer, NJC1
Anten, MM1
Wesseling, P1
Postma, AA1
De Ruysscher, D1
Lambin, P1
Qiang, L1
Yang, S1
Cui, YH1
He, YY1
Kumar, SK1
Jacobus, SJ1
Cohen, AD1
Weiss, M1
Callander, N1
Singh, AK1
Parker, TL1
Menter, A1
Parsons, B1
Kumar, P1
Kapoor, P1
Rosenberg, A1
Zonder, JA1
Faber, E1
Lonial, S1
Anderson, KC1
Richardson, PG1
Orlowski, RZ1
Wagner, LI1
Rajkumar, SV1
Li, G1
Hou, G1
Cui, J1
Xie, H1
Sun, Z1
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Dunstand-Guzmán, E1
Hallal-Calleros, C1
Hernández-Velázquez, VM1
Canales-Vargas, EJ1
Domínguez-Roldan, R1
Pedernera, M1
Peña-Chora, G1
Flores-Pérez, I1
Kim, MJ1
Han, C1
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Park, HJ1
Ding, D1
Boyd, K1
Rothenberger, C1
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Carmichael, P1
Linser, PJ1
Tanokura, M1
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Divya, KP1
Dharuman, V1
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Ogorodnikova, OL1
Parmon, VN1
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Liao, W1
Zhang, P1
Nabi, M1
Cai, Y1
Li, F1
Alsbou, EM1
Omari, KW1
Adeosun, WA1
Asiri, AM1
Marwani, HM1
Barral, M1
Jemal-Turki, A1
Beuvon, F1
Soyer, P1
Camparo, P1
Cornud, F1
Atwater, BD1
Jones, WS1
Loring, Z1
Friedman, DJ1
Namburath, M1
Papirio, S1
Moscariello, C1
Di Costanzo, N1
Pirozzi, F1
Alappat, BJ1
Sreekrishnan, TR1
Volpin, F1
Woo, YC1
Kim, H1
Freguia, S1
Jeong, N1
Choi, JS2
Phuntsho, S1
Shon, HK1
Domínguez-Zambrano, E1
Pedraza-Chaverri, J1
López-Santos, AL1
Medina-Campos, ON1
Cruz-Rivera, C1
Bueno-Hernández, F1
Espinosa-Cuevas, A1
Bulavaitė, A1
Dalgediene, I1
Michailoviene, V1
Pleckaityte, M1
Sauerbier, P1
Köhler, R1
Renner, G1
Militz, H1
Llanos, O1
Lee, S1
Salinas, JL1
Sanchez, R1
Assy, JGPL1
Esper, HR1
Quiroga, MMM1
Brandão, ADS1
Said, RDC1
Pinheiro, OC1
Ribeiro, APDS1
Santo, MCCDE1
França, FOS1
Campillo, JT1
Chabot, EB1
Awaca-Uvon, NP1
Tambwe, JP1
Kuyangisa-Simuna, G1
Boussinesq, M1
Chesnais, CB1
Pion, SD1
Salam, RA2
Das, JK1
Bhutta, ZA3
Han, JY1
Ahn, HK1
Ryu, HM1
Koren, G1
Namara, B1
Nash, S2
Lule, SA3
Akurut, H4
Mpairwe, H7
Akello, F2
Tumusiime, J1
Kizza, M4
Kabagenyi, J1
Nkurunungi, G1
Muhangi, L10
Webb, EL7
Muwanga, M11
Elliott, AM12
Ali, MS1
Saeed, K1
Rashid, I1
Ijaz, M1
Akbar, H1
Rashid, M1
Ashraf, K1
Persichino, JG1
Miller, LG1
Ridler, AL1
Miller, CM2
Leathwick, DM2
Ganesh, S1
Garland, CB1
Bruce, HM1
Gyorkos, TW3
St-Denis, K1
Erçetin, C1
Özden, I1
Iyibozkurt, C1
Güven, K1
Serin, K1
Bilge, O1
Tekant, Y1
Alper, A1
Emre, A1
Bhattacharyya, SK1
Bhattacharya, S1
Alam, H1
Patua, B1
Chattopadhyay, P1
Ndibazza, J8
Nampijja, M7
Apule, B2
Lule, S2
Kizito, D6
Kakande, M1
Jones, FM2
Fitzsimmons, CM1
Rodrigues, LC2
Dunne, DW2
Mofid, LS2
Casapía, M1
Montresor, A3
Rahme, E1
Fraser, WD1
Marquis, GS1
Vercruysse, J1
Allen, LH1
Haider, BA2
Humayun, Q2
Bal, M1
Sahu, PK1
Mandal, N1
Satapathy, AK1
Ranjit, M1
Kar, SK1
Mentzer, AJ1
Smits, G1
van der Klis, FR1
Henao-Martínez, AF1
Madinger, N1
Scholes, SF1
Reichel, R1
Willmington, J1
Daniel, R1
Soleimani, A1
Sahebjam, M1
Marzban, M1
Shirani, S1
Abbasi, A1
Ndyomugyenyi, R1
Kabatereine, N2
Olsen, A1
Magnussen, P1
Liabsuetrakul, T1
Chaikongkeit, P1
Korviwattanagarn, S1
Petrueng, C1
Chaiya, S1
Hanvattanakul, C1
Kongkitkul, P1
Sinthuuthai, C1
Kalong, N1
Ongsawang, D1
Ungsathapornpon, S1
Ameeroh, A1
Bavonnarongdet, P1
Buadung, A1
Mihrshahi, S2
Casey, GJ2
Phuc, TQ2
Thach, DT1
Tien, NT2
Biggs, BA2
Phu, LB1
Caruana, SR1
Thach, TD1
Asnis, D1
Kazakov, J1
Toronjadze, T1
Bern, C1
Garcia, HH1
McAuliffe, I1
Bishop, H1
Lee, L1
Grossmann, R1
Garcia, MA1
Di John, D1
Akishule, D2
Kiggundu, M1
Ameke, C2
Oweka, J1
Kizindo, R3
Duong, T1
Kleinschmidt, I1
Pallua, K1
Putz, G1
Mitterschiffthaler, G1
Brezinka, C1
Biebl, M1
Paal, P1
Moliner, JV1
Valverde, AG1
Sorolla, JM1
Smith, JL1
Brooker, S2
Mawa, PA3
Namatovu, A1
Kyosiimire-Lugemwa, J2
Nanteza, B1
Woodburn, PW1
Akello, M1
Lyadda, N1
Bukusuba, J1
Kihembo, M2
Nabulime, J1
Namujju, PB3
Tweyongyere, R2
Whitworth, JA4
Ngom-wegi, S1
Tumusime, J1
Fitzsimmons, C1
Teruel, M1
Dercole, J1
Catalano, R1
Erol, T1
Altay, H1
Tarim, E1
Mawa, P1
Acevedo-Ramírez, PM1
Quiroz-Romero, H1
Cruz-Mendoza, I1
Ulloa-Arvizu, R1
Ibarra-Velarde, F1
Voigt, K1
Scheuerle, M1
Hamel, D1
Pfister, K1
Nkurunziza, P1
Kaleebu, P1
Novobilský, A1
Averpil, HB1
Höglund, J1
Urassa, DP1
Nystrom, L1
Carlsted, A1
Rutebarika, D1
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Tweyongere, R1
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Dupouy-Camet, J1
Kociecka, W1
Bruschi, F1
Bolas-Fernandez, F1
Pozio, E1
Allen, HE1
Crompton, DW1
de Silva, N1
LoVerde, PT1
Olds, GR1
Capece, BP2
Navarro, M2
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Castells, G2
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Perez, F2
Carretero, A2
Ruberte, J2
Arboix, M3
Cristòfol, C3
Teruel, MT1
Felipe, AE1
Solana, HD1
Sallovitz, JM1
Lanusse, CE1
Can, D1
Oztekin, O2
Tinar, S1
Sanci, M1
Schellenberg, RS1
Tan, BJ1
Irvine, JD1
Stockdale, DR1
Gajadhar, AA1
Serhir, B1
Botha, J1
Armstrong, CA1
Woods, SA1
Blondeau, JM1
McNab, TL1
Gyapong, JO1
Chinbuah, MA1
Gyapong, M1
Cooney, RM1
Flanagan, KP1
Zehyle, E1
Auer, H3
Aspöck, H2
Quigley, MA3
Oweka-Onyee, J1
Shrimpton, R1
Dalmiya, N1
Darnton-Hill, I1
Gross, R1
Nkurunziza, PM1
Belisle, JT1
Yilmaz, N1
Kiymaz, N1
Etlik, O1
Yazici, T1
Atkinson, DS1
Haack, NA1
Alexander, RA1
Oliver, AM1
Waghorn, TS1
Potter, JF1
Sutherland, IA1
Morison, L1
Delatour, P2
Garnier, F1
Benoit, E1
Longin, C1
Parish, RC1
Gyurik, RJ1
Mezo-Menéndez, M1
Díez-Baños, P1
Morrondo-Pelayo, P1
Díez-Baños, N1
Golaszewski, T1
Susani, M1
Golaszewski, S1
Sliutz, G1
Bischof, G1
Kollaritsch, H1
Jüptner, J1
Theodorides, VJ1
Carakostas, MC1
Colaianne, JJ1
Freeman, JF1
Page, SW1
Liu, LX1
Weller, PF1
Horton, J1
Barger, IA1
Steel, JW1
Rodden, BR1
Gatongi, PM1
Scott, ME1
Ranjan, S1
Gathuma, JM1
Munyua, WK1
Cheruiyot, H1
Prichard, RK1
Franquelo, C1
Valladares, JE1
Filice, C1
Brunetti, E1
van Vliet, W1
Scheele, F1
Sibinga-Mulder, L1
Dekker, GA1
Al-Qudah, KM1
Sharif, LA1
Al-Rawashdeh, OF1
Al-Ani, FK1
Suarez, VR1
Iannucci, TA1
Cowden, J1
Hotez, P1
Torlesse, H1
Hodges, M1
Guyatt, HL1
Peshu, N1
Shulman, CE1
Srour, SF1
Sayfan, J1
Pérez, R1
Andaluz, A1
Garcia, F1
Montes, H1
Soetkino, R1
Carr-Locke, DL1
Khallaayoune, K1
Stromberg, BE1
Ward, JK1
Ferguson, DL1
Parkhurst, AM1
Berthelsen, J1
Nelson, MJ1
Wetzel, H1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Control Trial of the Use of Supplementary Food and Measures to Control Inflammation in Malnourished Pregnant Women to Improve Birth Outcomes[NCT03079388]1,489 participants (Actual)Interventional2017-02-27Completed
S. Japonicum and Pregnancy Outcomes: A Randomized, Double Blind, Placebo Controlled Trial (RCT)[NCT00486863]Phase 2370 participants (Actual)Interventional2007-08-31Completed
Activity of Mefloquine Against Urinary Schistosomiasis[NCT01132248]Phase 265 participants (Actual)Interventional2010-05-31Completed
Postpartum Deworming: Improving Breastfeeding and Optimizing Infant Growth[NCT01748929]Phase 41,010 participants (Actual)Interventional2014-02-24Completed
Alternative Chemotherapies for Lymphatic Filariasis (LF) Treatment and Elimination in Africa [Cote d'Ivoire][NCT02974049]189 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Change in Maternal Hemoglobin From 14 to 32 Weeks Gestation

Hemoglobin concentration in a venous blood sample collected at 14 and 32 weeks gestation was measured using a multi-analyte analyzer. Each participant's change in hemoglobin concentration between the two timepoints was determined, and the mean and standard deviation for each group calculated. (NCT00486863)
Timeframe: 14 weeks and 32 weeks gestation

Interventiongrams/deciliter (Mean)
Placebo Control at 12-16 Weeks Gestation-0.42
Praziquantel at 12-16 Weeks Gestation-0.44

Mean Change in Maternal Thigh Skinfold Thickness From 14 to 32 Weeks Gestation

Maternal fat stores were measured by thigh skinfold thickness obtained using a Holtain skinfold caliper. The thickness increase from 14 to 32 weeks was determined for each participant, and the mean and standard deviation calculated. (NCT00486863)
Timeframe: 14 and 32 weeks gestation

Interventionmillimeters (Mean)
Placebo Control at 12-16 Weeks Gestation0.08
Praziquantel at 12-16 Weeks Gestation0.08

Mean Change in Maternal Weight From 14 to 32 Weeks Gestation

Maternal weight gain was assessed by measuring participants' weight in kilograms. The weight increase from 14 to 32 weeks was determined for each participant, and the mean and standard deviation calculated. (NCT00486863)
Timeframe: 14 and 32 weeks gestation

Interventionkilograms (Mean)
Placebo Control at 12-16 Weeks Gestation0.33
Praziquantel at 12-16 Weeks Gestation0.32

Mean Newborn Birth Weight

Birth weight was collected for live infants at the time of delivery by a trained midwife, or within 24 hours of delivery for participants who chose to deliver at home with a helot, a birth attendant without formal training. (NCT00486863)
Timeframe: Within 24 hours of delivery.

Interventionkilograms (Mean)
Placebo Control at 12-16 Weeks Gestation2.85
Praziquantel at 12-16 Weeks Gestation2.85

Median Change in Maternal Transferrin Receptor:Ferritin Ratio From 14 to 32 Weeks Gestation

To assess total body iron, one needs to assess the storage compartment, which will contain sequestered iron, and the functional compartment, which represents bioavailable iron. Body iron status is defined by the two laboratory measurements that reflect these compartments, ferritin and serum transferrin receptor. The serum transferrin receptor:ferritin ratio has been shown in quantitative phlebotomy studies to provide an accurate assessment of total body iron over the entire range of status. At 14 and 32 weeks gestation, a blood sample was collected for assessment of total body iron by determination of the transferrin receptor:ferritin ratio. Each participant's change in ratio was calculated, and the median and interquartile range were determined for each group. (NCT00486863)
Timeframe: 14 weeks and 32 weeks gestation

Interventionratio (Median)
Placebo Control at 12-16 Weeks Gestation0.0
Praziquantel at 12-16 Weeks Gestation0.0

Median Maternal Hepcidin at 32 Weeks Gestation

Anemia of inflammation was assessed via maternal urine hepcidin levels. In response to inflammation, elevated serum levels of hepcidin is synthesized. Hepcidin causes sequestration of iron from bio-available forms to storage forms such as ferritin and decreases intestinal absorption of iron. Hepcidin was measured in participants' urine at 32 weeks gestation. (NCT00486863)
Timeframe: 32 weeks gestation

Interventionnanograms/milliliter (Median)
Placebo Control at 12-16 Weeks Gestation2.58
Praziquantel at 12-16 Weeks Gestation3.38

Number of Participants Experiencing Fetal Loss by Abortion

Abortion was defined by the protocol as bleeding followed by fetal loss as supported by ultrasound before 20 weeks gestation. Abortion was an important safety outcome measure due to the fact that abortion would occur closer to the time of dosing than miscarriage or stillbirth. Participants were observed in hospital for 24 hours after dosing and asked to return for any bleeding at any time. (NCT00486863)
Timeframe: After dosing and before 20 weeks gestation

Interventionparticipants (Number)
Placebo Control at 12-16 Weeks Gestation0
Praziquantel at 12-16 Weeks Gestation0

Number of Participants Reporting Serious Adverse Events Within 24 Hours of Dosing

Participants were observed in hospital for 24 hours after dosing for serious adverse events. Serious adverse events included any untoward medical occurrence that resulted in death; was life threatening; was a persistent/significant disability/incapacity; required in-patient hospitalization or prolongation thereof (for reasons other than the 24-hour observation period); resulted in a congenital anomaly/birth defect; or may have jeopardized the participant, or required intervention to prevent one of these outcomes. (NCT00486863)
Timeframe: Within 24 hours of dosing

Interventionparticipants (Number)
Placebo Control at 12-16 Weeks Gestation0
Praziquantel at 12-16 Weeks Gestation0

Number of Participants Whose Infant Was Born With Congenital Anomalies

The newborn was examined by the midwife at delivery and within 2-6 days of delivery to assess the presence of congenital anomalies and well-being. The newborn was also examined by study pediatrician at 28 days of life. (NCT00486863)
Timeframe: At delivery, within 2-6 days of delivery, and at 28 days

Interventionparticipants (Number)
Placebo Control at 12-16 Weeks Gestation1
Praziquantel at 12-16 Weeks Gestation1

Number of Participants Whose Pregnancy Resulted in a Live Birth

Each participant was followed until delivery to record if the outcome of the pregnancy was a live birth. Live births were defined as the complete expulsion or extraction from its mother of a product of conception, irrespective of the duration of the pregnancy, which, after such separation, breathes or shows any other evidence of life such as heartbeat, umbilical cord pulsation, or definite movement of voluntary muscles, whether the umbilical cord had been cut or the placenta was attached. (NCT00486863)
Timeframe: At delivery

Interventionparticipants (Number)
Placebo Control at 12-16 Weeks Gestation181
Praziquantel at 12-16 Weeks Gestation181

Number of Participants With Pre-eclampsia

Participants were assessed for the presence of pre-eclampsia at both the 22 and 32 week visits. Pre-eclampsia was defined by the presence of proteinurea (2+ protein on urine dipstick) and a single diastolic blood pressure reading of 100 millimiters of mercury (mm Hg) or above OR more than one reading, four hours apart, of 90 mm Hg or above. (NCT00486863)
Timeframe: 22 weeks and 32 weeks

Interventionparticipants (Number)
Placebo Control at 12-16 Weeks Gestation0
Praziquantel at 12-16 Weeks Gestation0

Number of Subjects With Reduction in S. Japonicum Egg Counts From Screening to 22 Weeks Gestation of Greater Than 90 Percent

Parasitologic response to treatment was evaluated by counting S. japonicum eggs per gram of stool at screening and again at 22 weeks gestation. Success of treatment was pre-specified as greater than 90 percent reduction in egg count from screening to 22 weeks gestation. (NCT00486863)
Timeframe: Screening and 22 weeks gestation

Interventionparticipants (Number)
Placebo Control at 12-16 Weeks Gestation92
Praziquantel at 12-16 Weeks Gestation157

4-hydroxy Praziquantel Pharmacokinetic Concentrations

Since pregnancy is associated with increased cytochrome P450 activity and physiologic changes in the gastrointestinal tract that tend to reduce drug absorption, praziquantel pharmacokinetics may be affected by pregnancy. Thus, the metabolite-to-parent drug ratio may serve as a differential marker to help determine if variability in drug exposure following oral administration during pregnancy is due to altered metabolism or drug absorption. Samples that were collected from subjects who were randomized to receive praziquantel were analyzed for praziquantel and 4-hydroxy praziquantel concentrations. Assays were performed using high performance liquid chromatography-electrospray mass spectrometry in the University of California at San Diego Pediatric Clinical Pharmacology Laboratory. Descriptive statistics were obtained for concentrations at each of the four sparse sampling timepoints. (NCT00486863)
Timeframe: 4.5 and 8 hours after the first praziquantel dose (subjects assigned to an even study number) or 6 and 10 hours after the first praziquantel dose (subjects assigned to an odd study number).

Interventionng/ml (Median)
4.5 Hours, n=506 Hours, n=498 Hours, n=5010 Hours, n=49
Praziquantel at 12-16 Weeks Gestation4020.14590.85373.74304.1

Newborn Median Serum Transferrin Receptor:Ferritin Ratio

To assess total body iron, the serum transferrin receptor:ferritin ratio was assessed in the infant. At delivery, a heel stick blood sample and a cord blood sample were collected for assessment of total body iron by determination of the transferrin receptor:ferritin ratio. (NCT00486863)
Timeframe: 0-6 days after delivery.

,
Interventionratio (Median)
Cord BloodHeel Stick
Placebo Control at 12-16 Weeks Gestation1.760.00
Praziquantel at 12-16 Weeks Gestation1.330.00

Number of Participants Reporting Abnormalities in Clinical Chemistry Assessments Within 24 Hours of Dosing

Toxicity to maternal kidney and liver was assessed by laboratory parameters collected just before and 24 hours after dosing. Specifically, blood was drawn just before the dose at 12-16 weeks gestation to determine baseline blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and bilirubin. Blood was then drawn 24 hours after the second part of the split dose and before discharge from the hospital to assess any changes in these parameters. Any values that were 1.1 times the upper limit of normal or greater for the parameter were considered abnormal. (NCT00486863)
Timeframe: Just before and 24 hours after dosing

,
Interventionparticipants (Number)
Blood Urea Nitrogen (BUN) AbnormalCreatinine AbnormalAspartate Aminotransferase (AST) AbnormalAlanine Aminotransferase (ALT) AbnormalBilirubin Abnormal
Placebo Control at 12-16 Weeks Gestation12723813127
Praziquantel at 12-16 Weeks Gestation13739910137

Number of Participants Reporting Abnormalities in Hematology Assessments Within 24 Hours of Dosing

Toxicity to maternal bone marrow, kidney, and liver was assessed by laboratory parameters collected just before and 24 hours after dosing. Specifically, blood was drawn just before the dose at 12-16 weeks gestation to determine baseline complete blood count, including white blood count (WBC), platelets, and hemoglobin. Blood was then drawn 24 hours after the second part of the split dose and before discharge from the hospital to assess any changes in these parameters. White blood count was abnormal at or above 10,800 or at or below 3500 cells/square millimeter (sq mm), platelets were abnormal at or below 140,000 cells/sq mm, and hemoglobin was abnormal at or below 10.9 grams/deciliter (g/dL). (NCT00486863)
Timeframe: Just before and 24 hours after dosing

,
Interventionparticipants (Number)
White Blood Cell AbnormalPlatelets AbnormalHemoglobin Abnormal
Placebo Control at 12-16 Weeks Gestation69354
Praziquantel at 12-16 Weeks Gestation60056

Praziquantel Pharmacokinetic Concentrations

Two plasma samples were collected during the overnight hospitalization from approximately 200 subjects that remained at the time of study modification to incorporate PK studies. Subjects had samples collected based on one of two sample collection strategies: 4.5 and 8 hr after the first praziquantel dose or 6 and 10 hr after the first praziquantel dose. Subjects randomized to an even study number were assigned to the 4.5 and 8 hour schedule. Subjects randomized to an odd study number were assigned to the 6 and 10 hour schedule. Samples only from subjects randomized to receive praziquantel were analyzed for praziquantel. Samples drawn from subjects randomized to the control group were not analyzed. Praziquantel concentrations (ng/ml) were assayed using high performance liquid chromatography-electrospray mass spectrometry in the University of California at San Diego Pediatric Clinical Pharmacology Laboratory. (NCT00486863)
Timeframe: 4.5 and 8 hours after the first praziquantel dose (subjects assigned to an even study number) or 6 and 10 hours after the first praziquantel dose (subjects assigned to an odd study number).

Interventionng/mL (Median)
4.5 Hours, n=506 Hours, n=498 Hours, n=5010 Hours, n=49
Praziquantel at 12-16 Weeks Gestation814.7945.2687.8422.2

Reviews

12 reviews available for albendazole and Pregnancy

ArticleYear
Treatment of soil-transmitted helminth infections in pregnancy: a systematic review and meta-analysis of maternal outcomes.
    Journal of travel medicine, 2020, 03-13, Volume: 27, Issue:2

    Topics: Albendazole; Animals; Anthelmintics; Female; Helminthiasis; Helminths; Humans; Pregnancy; Soil; Trav

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Effect of mass deworming with antihelminthics for soil-transmitted helminths during pregnancy.
    The Cochrane database of systematic reviews, 2021, 05-17, Volume: 5

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Bias; Female; Helminthiasis; Humans; Intestinal

2021
Effect of mass deworming with antihelminthics for soil-transmitted helminths during pregnancy.
    The Cochrane database of systematic reviews, 2021, 05-17, Volume: 5

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Bias; Female; Helminthiasis; Humans; Intestinal

2021
Effect of mass deworming with antihelminthics for soil-transmitted helminths during pregnancy.
    The Cochrane database of systematic reviews, 2021, 05-17, Volume: 5

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Bias; Female; Helminthiasis; Humans; Intestinal

2021
Effect of mass deworming with antihelminthics for soil-transmitted helminths during pregnancy.
    The Cochrane database of systematic reviews, 2021, 05-17, Volume: 5

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Bias; Female; Helminthiasis; Humans; Intestinal

2021
Systematic review of exposure to albendazole or mebendazole during pregnancy and effects on maternal and child outcomes, with particular reference to exposure in the first trimester.
    International journal for parasitology, 2019, Volume: 49, Issue:7

    Topics: Albendazole; Anthelmintics; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Mebenda

2019
Effect of administration of antihelminthics for soil-transmitted helminths during pregnancy.
    The Cochrane database of systematic reviews, 2015, Jun-18, Issue:6

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Female; Helminthiasis; Humans; Iron Compounds;

2015
Effect of administration of antihelminthics for soil transmitted helminths during pregnancy.
    The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Female; Helminthiasis; Humans; Iron Compounds;

2009
Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review.
    Tropical medicine & international health : TM & IH, 2010, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Aged; Albendazole; Anemia; Anthelmintics; Child; Child, Preschool; Female; Hemogl

2010
Opinion on the diagnosis and treatment of human trichinellosis.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:8

    Topics: Adult; Albendazole; Animals; Anthelmintics; Child; Female; Humans; Pregnancy; Randomized Controlled

2002
New policies for using anthelmintics in high risk groups.
    Trends in parasitology, 2002, Volume: 18, Issue:9

    Topics: Albendazole; Animals; Anthelmintics; Female; Humans; Infant; Lactation; Mebendazole; Pregnancy; Risk

2002
[Nosology and epidemiology of human toxocarosis--the recent situation in Austria].
    Wiener klinische Wochenschrift, 2004, Volume: 116 Suppl 4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anthelmin

2004
Strongyloidiasis and other intestinal nematode infections.
    Infectious disease clinics of North America, 1993, Volume: 7, Issue:3

    Topics: Adult; Albendazole; Animals; Dogs; Female; Humans; Intestinal Diseases, Parasitic; Ivermectin; Male;

1993
Mebendazole and albendazole treatment of geohelminth infections in children and pregnant women.
    The Pediatric infectious disease journal, 2000, Volume: 19, Issue:7

    Topics: Adolescent; Albendazole; Animals; Anthelmintics; Antinematodal Agents; Child; Child, Preschool; Fema

2000

Trials

21 trials available for albendazole and Pregnancy

ArticleYear
A novel intervention combining supplementary food and infection control measures to improve birth outcomes in undernourished pregnant women in Sierra Leone: A randomized, controlled clinical effectiveness trial.
    PLoS medicine, 2021, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Albendazole; Anti-Bacterial Agents; Antiprotozoal Agents; Azithromycin; Dysbiosis

2021
Hookworm re-infection rate and efficacy of single-dose albendazole among pregnant women in Debre Elias District, Northwest Ethiopia: A single-arm trial.
    Tropical doctor, 2022, Volume: 52, Issue:2

    Topics: Albendazole; Ancylostomatoidea; Animals; Anthelmintics; Cross-Sectional Studies; Ethiopia; Female; H

2022
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Effects of treating helminths during pregnancy and early childhood on risk of allergy-related outcomes: Follow-up of a randomized controlled trial.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2017, Volume: 28, Issue:8

    Topics: Albendazole; Anthelmintics; Asthma; Child; Child, Preschool; Double-Blind Method; Female; Follow-Up

2017
Production responses and cost-benefit of long-acting pre-lambing anthelmintic treatment of yearling ewes in two commercial flocks in New Zealand.
    New Zealand veterinary journal, 2019, Volume: 67, Issue:2

    Topics: Albendazole; Animals; Anthelmintics; Cobalt; Cost-Benefit Analysis; Delayed-Action Preparations; Fem

2019
Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2014, Volume: 25, Issue:5

    Topics: Albendazole; Anthelmintics; Child, Preschool; Cohort Studies; Double-Blind Method; Eczema; Female; H

2014
Maternal Deworming Research Study (MADRES) protocol: a double-blind, placebo-controlled randomised trial to determine the effectiveness of deworming in the immediate postpartum period.
    BMJ open, 2015, Jun-17, Volume: 5, Issue:6

    Topics: Adult; Albendazole; Anthelmintics; Breast Feeding; Cost-Benefit Analysis; Double-Blind Method; Femal

2015
The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on antibody responses to routine immunisations given in infancy: Secondary analysis of a randomised controlled trial.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:2

    Topics: Adult; Albendazole; Animals; Anthelmintics; Antibodies, Helminth; Antibody Formation; Female; Helmin

2017
Efficacy of ivermectin and albendazole alone and in combination for treatment of soil-transmitted helminths in pregnancy and adverse events: a randomized open label controlled intervention trial in Masindi district, western Uganda.
    The American journal of tropical medicine and hygiene, 2008, Volume: 79, Issue:6

    Topics: Abortion, Spontaneous; Albendazole; Antiparasitic Agents; Birth Weight; Congenital Abnormalities; Dr

2008
Effects of deworming during pregnancy on maternal and perinatal outcomes in Entebbe, Uganda: a randomized controlled trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Feb-15, Volume: 50, Issue:4

    Topics: Albendazole; Anemia; Animals; Anthelmintics; Birth Weight; Double-Blind Method; Female; Helminthiasi

2010
Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2011, Jan-01, Volume: 377, Issue:9759

    Topics: Adult; Albendazole; Anthelmintics; Communicable Diseases; Dose-Response Relationship, Drug; Double-B

2011
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2011, Volume: 22, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Dermatitis, Atopic; Double-Blind Method; Female; Helminthiasis; H

2011
Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child?
    Parasitology, 2011, Volume: 138, Issue:12

    Topics: Albendazole; Ancylostomatoidea; Anemia; Animals; Anthelmintics; Benzimidazoles; Birth Weight; Child;

2011
The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda.
    Journal of acquired immune deficiency syndromes (1999), 2012, Jul-01, Volume: 60, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Cohort Studies; Double-Blind Method; Female; Helminthiasis; HIV I

2012
The field evaluation of albendazole and triclabendazole efficacy against Fasciola hepatica by coproantigen ELISA in naturally infected sheep.
    Veterinary parasitology, 2012, Nov-23, Volume: 190, Issue:1-2

    Topics: Albendazole; Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Benzimidazoles; Bioma

2012
Effectiveness of routine antihelminthic treatment on anaemia in pregnancy in Rufiji District, Tanzania: a cluster randomised controlled trial.
    East African journal of public health, 2011, Volume: 8, Issue:3

    Topics: Adult; Albendazole; Anemia; Anemia, Iron-Deficiency; Anthelmintics; Antimalarials; Cluster Analysis;

2011
Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Adult; Albendazole; Anthelmintics; Child, Preschool; Double-Blind Method; Eczema; Female; Helminthia

2012
Placental and fetal toxicity of albendazole sulphoxide in Wistar rats.
    Veterinary and human toxicology, 2003, Volume: 45, Issue:3

    Topics: Abnormalities, Multiple; Administration, Oral; Albendazole; Animals; Anthelmintics; Dose-Response Re

2003
A randomised controlled trial of the effects of albendazole in pregnancy on maternal responses to mycobacterial antigens and infant responses to Bacille Calmette-Guérin (BCG) immunisation [ISRCTN32849447].
    BMC infectious diseases, 2005, Dec-21, Volume: 5

    Topics: Adult; Albendazole; Animals; Antigens, Bacterial; BCG Vaccine; Double-Blind Method; Female; Helminth

2005
The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and e
    Clinical trials (London, England), 2007, Volume: 4, Issue:1

    Topics: Albendazole; Animals; Antiparasitic Agents; Child; Double-Blind Method; Female; Helminthiasis; Helmi

2007
Anthelminthic treatment and haemoglobin concentrations during pregnancy.
    Lancet (London, England), 2000, Sep-23, Volume: 356, Issue:9235

    Topics: Adolescent; Adult; Albendazole; Anemia; Anthelmintics; Dietary Supplements; Female; Folic Acid; Helm

2000

Other Studies

56 other studies available for albendazole and Pregnancy

ArticleYear
Neurocysticercosis Complicating Pregnancy.
    Obstetrics and gynecology, 2022, 08-01, Volume: 140, Issue:2

    Topics: Albendazole; Anthelmintics; Female; Headache; Humans; Hydrocephalus; Infant, Newborn; Neurocysticerc

2022
Treatment of pregnant mice with ABZ had no effect on the immune response of their offspring infected with Trichinella spiralis.
    International immunopharmacology, 2023, Volume: 121

    Topics: Albendazole; Animals; Cytokines; Female; Humans; Immunity; Mice; Pregnancy; Trichinella spiralis; Tr

2023
A 28-Year-Old Pregnant Woman With a Lung Abscess and Complicated Pleural Effusion.
    Chest, 2020, Volume: 158, Issue:5

    Topics: Adult; Albendazole; Anthelmintics; Diagnosis, Differential; Drainage; Echinococcosis, Pulmonary; Fem

2020
Unusual case of lagochilascariasis with breast involvement: the first case report in pregnancy.
    Revista do Instituto de Medicina Tropical de Sao Paulo, 2020, Volume: 62

    Topics: Abscess; Adolescent; Adult; Albendazole; Animals; Anti-Bacterial Agents; Antiparasitic Agents; Ascar

2020
Effect of Lymphatic Filariasis and Hookworm Infection on Pregnancy Course and Outcome in Women Living in the Democratic Republic of the Congo.
    The American journal of tropical medicine and hygiene, 2021, 05-03, Volume: 104, Issue:6

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Antigens, Helminth; Democratic Republic of the

2021
Foetal outcomes after exposure to albendazole in early pregnancy.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2017, Volume: 37, Issue:8

    Topics: Adult; Albendazole; Anthelmintics; Case-Control Studies; Female; Humans; Pregnancy; Pregnancy Outcom

2017
Anthelmintic Drugs: Their Efficacy and Cost-Effectiveness in Different Parity Cattle.
    The Journal of parasitology, 2018, Volume: 104, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Cattle; Cattle Diseases; Cost-Benefit Analysis; Fats; Feces; Fe

2018
Pregnancy Screening and Monitoring of Albendazole Therapy for Neurocysticercosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 11-13, Volume: 67, Issue:11

    Topics: Albendazole; Anthelmintics; Humans; Hygiene; Neurocysticercosis; Pregnancy; Tropical Medicine; Unite

2018
Hepatic hydatid disease requiring urgent treatment during pregnancy.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2013, Volume: 19, Issue:2

    Topics: Adult; Albendazole; Anastomosis, Surgical; Anticestodal Agents; Drainage; Echinococcosis, Hepatic; F

2013
Dilemmas encountered while dealing a pregnancy complicated by pelvic Hydatid disease.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:5

    Topics: Adult; Albendazole; Anticestodal Agents; Cesarean Section; Dystocia; Echinococcosis; Female; Humans;

2013
Maternal Infection Is a Risk Factor for Early Childhood Infection in Filariasis.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:7

    Topics: Adult; Aging; Albendazole; Antigens, Helminth; Cohort Studies; Diethylcarbamazine; Female; Filariasi

2015
The Case for Maternal Postpartum Deworming.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Albendazole; Anthelmintics; Drug Administration Schedule; Female; Global Health;

2017
Anemia During Pregnancy-The Enemies Within.
    The American journal of the medical sciences, 2017, Volume: 353, Issue:3

    Topics: Administration, Oral; Adult; Albendazole; Anemia; Animals; Female; Hematocrit; Hemoglobins; Humans;

2017
Malformations including hemimelia and amelia in sheep.
    The Veterinary record, 2008, Jul-19, Volume: 163, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; Ectromelia; Female; Mebendazole; Pregnancy; Sheep; Sheep Diseas

2008
Hydatid cyst of the right ventricle in early pregnancy.
    Echocardiography (Mount Kisco, N.Y.), 2008, Volume: 25, Issue:7

    Topics: Abortion, Spontaneous; Adult; Albendazole; Cardiac Surgical Procedures; Combined Modality Therapy; E

2008
Epidemiology and the effect of treatment of soil-transmitted helminthiasis in pregnant women in southern Thailand.
    The Southeast Asian journal of tropical medicine and public health, 2009, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; Ascariasis; Ascaris lumbr

2009
The effectiveness of 4 monthly albendazole treatment in the reduction of soil-transmitted helminth infections in women of reproductive age in Viet Nam.
    International journal for parasitology, 2009, Jul-15, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Albendazole; Animals; Feces; Female; Fertilizers; Helminthiasis; Hookworm Infecti

2009
Lessons learned from implementation of a demonstration program to reduce the burden of anemia and hookworm in women in Yen Bai Province, Viet Nam.
    BMC public health, 2009, Jul-28, Volume: 9

    Topics: Adolescent; Adult; Albendazole; Anemia, Iron-Deficiency; Anthelmintics; Female; Folic Acid; Guidelin

2009
Neurocysticercosis in the infant of a pregnant mother with a tapeworm.
    The American journal of tropical medicine and hygiene, 2009, Volume: 81, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; Anti-Inflammatory Agents; Anticonvulsants; Carbamazepine; Dexam

2009
Management of hepatic echinococcosis in pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2010, Volume: 109, Issue:2

    Topics: Adult; Albendazole; Cesarean Section; Diphenhydramine; Echinococcosis, Hepatic; Famotidine; Female;

2010
[Loa loa meningoencephalitis secondary to treatment with mebendazol].
    Medicina clinica, 2011, Feb-26, Volume: 136, Issue:5

    Topics: Adolescent; Albendazole; Animals; Anthelmintics; Brain Damage, Chronic; Central Nervous System Helmi

2011
Evaluation of potential embryo toxicity of albendazole sulphoxide in CF1 mice.
    Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2011, Volume: 35, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Blastocyst; Embryo, Mammalian; Female; Humans; Male; Mice; Preg

2011
A pericardial hydatid cyst and pregnancy.
    Acta cardiologica, 2011, Volume: 66, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Echinococcosis; Echinococcosis, Hepatic; Female; Heart Diseases;

2011
Gastrointestinal nematodes in rotationally grazing ewes in the mountainous region of central Mexico.
    Journal of helminthology, 2013, Volume: 87, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Climate; Feces; Female; Gastrointestinal Diseases; Ivermectin;

2013
[High perinatal mortality associated with triple anthelmintic resistance in a German sheep flock].
    Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2012, Apr-24, Volume: 40, Issue:2

    Topics: Abortion, Veterinary; Albendazole; Animals; Animals, Newborn; Anthelmintics; Diarrhea; Drug Resistan

2012
Albendazole sulphoxide enantiomers in pregnant rats' embryo concentrations and developmental toxicity.
    Veterinary journal (London, England : 1997), 2003, Volume: 165, Issue:3

    Topics: Abnormalities, Multiple; Administration, Oral; Albendazole; Animals; Anthelmintics; Bone and Bones;

2003
Hepatic and splenic hydatid cyst during pregnancy: a case report.
    Archives of gynecology and obstetrics, 2003, Volume: 268, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Delivery, Obstetric; Diagnosis, Differential; Echinococcosis; Ech

2003
An outbreak of trichinellosis due to consumption of bear meat infected with Trichinella nativa, in 2 northern Saskatchewan communities.
    The Journal of infectious diseases, 2003, Sep-15, Volume: 188, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anti-Inflammatory Agents; Antinema

2003
Inadvertent exposure of pregnant women to ivermectin and albendazole during mass drug administration for lymphatic filariasis.
    Tropical medicine & international health : TM & IH, 2003, Volume: 8, Issue:12

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adolescent; Adult; Albendazole; Child Developmen

2003
Review of surgical management of cystic hydatid disease in a resource limited setting: Turkana, Kenya.
    European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:11

    Topics: Abdomen; Adolescent; Adult; Aged; Albendazole; Anticestodal Agents; Child; Child, Preschool; Echinoc

2004
Helminth infection during pregnancy and development of infantile eczema.
    JAMA, 2005, Oct-26, Volume: 294, Issue:16

    Topics: Albendazole; Anthelmintics; Eczema; Female; Helminthiasis; Humans; Infant; Infant, Newborn; Poisson

2005
Micronutrient supplementation in pregnancy.
    Lancet (London, England), 2005, Dec-10, Volume: 366, Issue:9502

    Topics: Albendazole; Anthelmintics; Birth Weight; Female; Humans; Infant Mortality; Infant, Newborn; Micronu

2005
Primary hydatid cyst of the brain during pregnancy.
    Neurologia medico-chirurgica, 2006, Volume: 46, Issue:8

    Topics: Adult; Albendazole; Antiprotozoal Agents; Brain; Echinococcosis; Female; Humans; Pregnancy; Pregnanc

2006
Drenching adult ewes: implications of anthelmintic treatments pre- and post-lambing on the development of anthelmintic resistance.
    New Zealand veterinary journal, 2006, Volume: 54, Issue:6

    Topics: Albendazole; Animal Husbandry; Animals; Anthelmintics; Antinematodal Agents; Drug Resistance; Feces;

2006
Albendazole: worms and hydatid disease.
    Lancet (London, England), 1984, Sep-22, Volume: 2, Issue:8404

    Topics: Albendazole; Anthelmintics; Benzimidazoles; Echinococcosis; Female; Humans; Nematode Infections; Pre

1984
A correlation of toxicity of albendazole and oxfendazole with their free metabolites and bound residues.
    Journal of veterinary pharmacology and therapeutics, 1984, Volume: 7, Issue:2

    Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Embryo, Mammalian; Female; Kinetics; Microsomes

1984
Albendazole : a comparison of relay embryotoxicity with embryotoxicity of individual metabolites.
    Annales de recherches veterinaires. Annals of veterinary research, 1981, Volume: 12, Issue:2

    Topics: Abnormalities, Drug-Induced; Albendazole; Animals; Anthelmintics; Benzimidazoles; Cattle; Chemical P

1981
Faecal egg output, contamination of pastures and serum pepsinogen concentrations in heifers with natural gastrointestinal nematode infections in north-west Spain.
    Journal of helminthology, 1995, Volume: 69, Issue:1

    Topics: Albendazole; Animal Feed; Animals; Cattle; Cattle Diseases; Feces; Female; Gastrointestinal Diseases

1995
A large hydatid cyst of the liver in pregnancy.
    Archives of gynecology and obstetrics, 1995, Volume: 256, Issue:1

    Topics: Adult; Albendazole; Echinococcosis, Hepatic; Female; Humans; Pregnancy; Pregnancy Complications, Par

1995
Albendazole and pregnancy.
    Applied parasitology, 1994, Volume: 35, Issue:2

    Topics: Adult; Albendazole; Echinococcosis, Hepatic; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy C

1994
Safety of albendazole in developing bovine fetuses.
    American journal of veterinary research, 1993, Volume: 54, Issue:12

    Topics: Administration, Oral; Albendazole; Animals; Cattle; Embryo, Mammalian; Embryonic and Fetal Developme

1993
The use of antiprotozoan and anthelmintic drugs during pregnancy and contraindications.
    The Journal of infection, 1993, Volume: 26, Issue:1

    Topics: Albendazole; Antimalarials; Drug Approval; Female; Humans; Infant, Newborn; Mutagens; Phenanthrenes;

1993
Effects of a controlled-release albendazole capsule on parasitism and production from grazing Merino ewes and lambs.
    Australian veterinary journal, 1993, Volume: 70, Issue:2

    Topics: Albendazole; Animals; Benzimidazoles; Capsules; Delayed-Action Preparations; Drug Resistance; Feces;

1993
Effects of three nematode anthelmintic treatment regimes on flock performance of sheep and goats under extensive management in semi-arid Kenya.
    Veterinary parasitology, 1997, Volume: 68, Issue:4

    Topics: Albendazole; Animals; Antinematodal Agents; Birth Weight; Desert Climate; Drug Administration Schedu

1997
Disposition of netobimin, albendazole, and its metabolites in the pregnant rat: developmental toxicity.
    Toxicology and applied pharmacology, 1997, Volume: 144, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Area Under Curve; Female; Guanidines; Pregnancy; Rats; Rats, Sp

1997
Percutaneous drainage of hydatid cysts.
    The New England journal of medicine, 1998, Feb-05, Volume: 338, Issue:6

    Topics: Albendazole; Child, Preschool; Drainage; Echinococcosis, Hepatic; Female; Humans; Pregnancy; Pregnan

1998
Echinococcosis of the liver during pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1995, Volume: 49, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Echinococcosis, Hepatic; Emigration and Immigration; Female; Huma

1995
Efficacy of closantel plus albendazole liquid suspension against natural infection of gastrointestinal parasites in camels.
    Veterinary parasitology, 1999, Mar-31, Volume: 82, Issue:2

    Topics: Albendazole; Animals; Anthelmintics; Camelus; Drug Combinations; Feces; Female; Helminthiasis, Anima

1999
Neurocysticercosis in pregnancy: a case initially diagnosed as eclampsia.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:5 Pt 2

    Topics: Adult; Albendazole; Anthelmintics; Brain Diseases; Cerebral Ventricles; Diagnosis, Differential; Ecl

1999
Hookworm and anaemia prevalence.
    Lancet (London, England), 2000, Dec-16, Volume: 356, Issue:9247

    Topics: Albendazole; Anemia; Anthelmintics; Comorbidity; Female; Hookworm Infections; Humans; Pregnancy; Pre

2000
Echinococcosis of the spleen during pregnancy.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:4

    Topics: Abortion, Induced; Adult; Albendazole; Anthelmintics; Echinococcosis, Hepatic; Female; Humans; Lapar

2001
Placental transfer of albendazole sulphoxide enantiomers in sheep.
    Veterinary journal (London, England : 1997), 2002, Volume: 163, Issue:2

    Topics: Administration, Oral; Albendazole; Animals; Anthelmintics; Area Under Curve; Female; Fetus; Gestatio

2002
Hydatid disease in pregnancy.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:6

    Topics: Adult; Albendazole; Anticestodal Agents; Echinococcosis, Hepatic; Female; Humans; Laparotomy; Pregna

2002
Effects of an anthelmintic treatment programme on sheep productivity in the Middle Atlas, Morocco.
    Tropical animal health and production, 1992, Volume: 24, Issue:3

    Topics: Albendazole; Animals; Female; Fenbendazole; Helminthiasis; Helminthiasis, Animal; Male; Morocco; Pre

1992
Internal parasite levels and response to anthelmintic treatment by beef cows and calves.
    Journal of animal science, 1991, Volume: 69, Issue:3

    Topics: Age Factors; Albendazole; Animals; Cattle; Cattle Diseases; Cestode Infections; Coccidiosis; Feces;

1991
[Use of albendazole in pregnant cows. Field studies on its safety in usage].
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1985, Volume: 32, Issue:5

    Topics: Abnormalities, Drug-Induced; Albendazole; Animals; Anthelmintics; Benzimidazoles; Cattle; Cattle Dis

1985